Page last updated: 2024-08-23

zidovudine and Adverse Drug Event

zidovudine has been researched along with Adverse Drug Event in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (13.33)18.2507
2000's6 (20.00)29.6817
2010's18 (60.00)24.3611
2020's2 (6.67)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Dollfus, C; Lemoine, A; Michot, J; Tounian, P; Viala, J1
Aweeka, F; Bradford, S; Browning, R; Coletti, A; Costello, D; Graham, B; Hughes, E; Kamthunzi, P; Kawalazira, R; Mmbaga, BT; Moye, J; Musoke, P; Nathoo, K; Norman, J; Owor, M; Purdue, L; Reding, C; Tierney, C; Whalen, ME; Wiesner, L; Ziemba, L1
Adeyeye, CM; Ali, I; Aliu, R; Awodele, O; Oni, Y1
Becker, C; Blohm, M; Hertling, S; Hollwitz, B; Kobbe, R; Kreuels, B; Laws, HJ; Martignoni, F; Neubert, J; Nguyen, TTT; Olah, K; Ole Jensen, BE; Oommen, PT; Schmidtke, S; Schulze-Sturm, U; Vasconcelos, MK1
Anugulruengkitt, S; Chokephaibulkit, K; Cressey, TR; Jantarabenjakul, W; Ounchanum, P; Pancharoen, C; Punnahitanon, S; Puthanakit, T; Sophonphan, J; Srirompotong, U; Suntarattiwong, P1
Anglaret, X; Bohoussou, F; Carrou, JL; Danel, C; Eholie, SP; Gabillard, D; Konan, R; Moh, R; Ouattara, E; Peytavin, G1
An, JH; Jang, HC; Jang, MO; Jung, SI; Kang, SJ; Kim, J; Kim, SE; Park, KH1
Bentaleb, H; Cisse, VM; Dia Badiane, NM; Dieng, AB; Diop, BM; Diop, SA; Diouf, A; Fortes Déguénonvo, L; Ka, D; Lakhe, NA; Leye, MM; Manga, MN; Ndour, CT; Seydi, M; Soumaré, M; Sow, PS1
Havens, PL; Hazra, R1
Arterburn, S; Castaño, E; Cheng, AK; Chuck, SL; Church, J; Deville, J; Enejosa, JV; Estripeaut, D; Gaur, A; Rathore, M; Rhee, MS; Saez-Llorens, X; White, K1
Bereznicki, LR; Bezabhe, WM; Bimirew, MA; Chalmers, L; Gee, P; Kassie, DM; Peterson, GM1
Butler, L; Civitello, L; Crain, MJ; Ellis, A; Hazra, R; Rich, K; Seage, GR; Van Dyke, RB; Williams, PL; Yildirim, C1
Anglaret, X; Danel, C; Eholie, S; Ello, F; Girard, PM; Hoelscher, M; Kroidl, A; Lennemann, T; Maganga, L; Mgaya, J; Moh, R; Pruvost, A; Saathoff, E; von Massow, F; Zuhse, R1
Christie, CD; Evans-Gilbert, T; Moore, J; Palmer, P; Pierre, RB; Pryce, C; Rodriguez, B; Steel-Duncan, J1
Brown, LB; Eron, JJ; Hosseinipour, MC; Kumwenda, JJ; Mhango, B; Mzinganjira, D; Phiri, S; van Oosterhout, JJ; Weigel, R1
Aurpibul, L; Capparelli, E; Chokephaibulkit, K; Cressey, TR; Eksaengsri, A; Hongsiriwon, S; Kabat, B; Limwongse, C; McIntosh, K; Muresan, P; Ngampiyaskul, C; Sirisanthana, V; Smith, ME; Toye, M; Wittawatmongkol, O; Yogev, R1
Agu, KA; Akpoigbe, KJ; Badru, T; Chabikuli, O; Eluwa, GI; Hamelmann, C1
Samuels, DC1
Hasegawa, R; Hirata-Koizumi, M; Miyake, S; Saito, M1
Rustin, P1
Mastroianni, AC1
Astrup, N1
Duesberg, PH1
Gil, A; Lavilla, P; López Dupla, JM; Pintado, V; Valencia, ME1

Reviews

4 review(s) available for zidovudine and Adverse Drug Event

ArticleYear
Computational models of antiviral toxicity.
    Current opinion in drug discovery & development, 2007, Volume: 10, Issue:1

    Topics: Anti-HIV Agents; Computer Simulation; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Lamivudine; Molecular Structure; Stavudine; Zidovudine

2007
Mitochondrial dysfunction in HIV infection: an overview of pathogenesis.
    Journal of HIV therapy, 2001, Volume: 6, Issue:1

    Topics: Anti-HIV Agents; Apoptosis; DNA, Mitochondrial; Drug-Related Side Effects and Adverse Reactions; Electron Transport; HIV Infections; Humans; Mitochondria; Permeability; Phosphorylation; Protease Inhibitors; Reverse Transcriptase Inhibitors; Zidovudine

2001
The role of drugs in the origin of AIDS.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1992, Volume: 46, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Drug-Related Side Effects and Adverse Reactions; Europe; Humans; Risk Factors; Substance-Related Disorders; United States; Zidovudine

1992
[Drug surveillance for adverse reactions in patients with human immunodeficiency virus infection].
    Anales de medicina interna (Madrid, Spain : 1984), 1990, Volume: 7, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Antitubercular Agents; Drug-Related Side Effects and Adverse Reactions; Ganciclovir; HIV Infections; Humans; Opportunistic Infections; Pentamidine; Product Surveillance, Postmarketing; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine

1990

Trials

5 trial(s) available for zidovudine and Adverse Drug Event

ArticleYear
Pharmacokinetics and Safety of Zidovudine, Lamivudine, and Lopinavir/Ritonavir in HIV-infected Children With Severe Acute Malnutrition in Sub-Saharan Africa: IMPAACT Protocol P1092.
    The Pediatric infectious disease journal, 2021, 05-01, Volume: 40, Issue:5

    Topics: Africa South of the Sahara; Anti-HIV Agents; Area Under Curve; Child, Preschool; Chromatography, Liquid; Cohort Studies; Drug Combinations; Drug Elimination Routes; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Lamivudine; Lopinavir; Male; Patient Safety; Ritonavir; Severe Acute Malnutrition; Tandem Mass Spectrometry; Zidovudine

2021
Early upper digestive tract side effects of zidovudine with tenofovir plus emtricitabine in West African adults with high CD4 counts.
    Journal of the International AIDS Society, 2013, Apr-30, Volume: 16

    Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cote d'Ivoire; Deoxycytidine; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Emtricitabine; Female; Gastrointestinal Diseases; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Tenofovir; Zidovudine

2013
A randomized, open-label study of the safety and efficacy of switching stavudine or zidovudine to tenofovir disoproxil fumarate in HIV-1-infected children with virologic suppression.
    The Pediatric infectious disease journal, 2015, Volume: 34, Issue:4

    Topics: Adenine; Adolescent; Anti-HIV Agents; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; RNA, Viral; Stavudine; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2015
Virological efficacy of 24-week fozivudine-based regimen in ART-naive patients from Tanzania and Côte d'Ivoire.
    AIDS (London, England), 2017, 02-20, Volume: 31, Issue:4

    Topics: Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Cote d'Ivoire; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Lipids; Male; Middle Aged; Prospective Studies; Sustained Virologic Response; Tanzania; Treatment Outcome; Zidovudine

2017
Pharmacokinetics and safety of a new paediatric fixed-dose combination of zidovudine/lamivudine/nevirapine in HIV-infected children.
    Antiviral therapy, 2011, Volume: 16, Issue:8

    Topics: Anti-HIV Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biological Availability; Body Weight; Child; Child, Preschool; Cytochrome P-450 CYP2B6; Drug Administration Schedule; Drug Combinations; Drug Dosage Calculations; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; HIV; HIV Infections; Humans; Infant; Lamivudine; Male; Nevirapine; Oxidoreductases, N-Demethylating; Reverse Transcriptase Inhibitors; Tablets; Zidovudine

2011

Other Studies

21 other study(ies) available for zidovudine and Adverse Drug Event

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Antiretroviral Prophylaxis: A Digestive Complication to Know.
    Pediatric emergency care, 2021, Dec-01, Volume: 37, Issue:12

    Topics: Anti-HIV Agents; Child; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Lamivudine; Zidovudine

2021
Patterns of adverse drug reaction signals in NAFDAC pharmacovigilance activities from January to June 2015: safety of drug use in Nigeria.
    Pharmacology research & perspectives, 2018, Volume: 6, Issue:5

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; Anti-HIV Agents; Child; Child, Preschool; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Middle Aged; Nevirapine; Nigeria; Pharmacovigilance; Sex Factors; Young Adult; Zidovudine

2018
Reducing Hematologic Toxicity With Short Course Postexposure Prophylaxis With Zidovudine for HIV-1 Exposed Infants With Low Transmission Risk.
    The Pediatric infectious disease journal, 2019, Volume: 38, Issue:7

    Topics: Anti-HIV Agents; Drug-Related Side Effects and Adverse Reactions; Female; Hematologic Diseases; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Pregnancy; Retrospective Studies; Zidovudine

2019
Safety of 6-week Neonatal Triple-combination Antiretroviral Postexposure Prophylaxis in High-risk HIV-exposed Infants.
    The Pediatric infectious disease journal, 2019, Volume: 38, Issue:10

    Topics: Anti-Retroviral Agents; Chemoprevention; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Nevirapine; Post-Exposure Prophylaxis; Prospective Studies; Thailand; Treatment Outcome; Zidovudine

2019
Clinical experience of raltegravir with abacavir/lamivudine or zidovudine/lamivudine in HIV-infected Korean adults.
    Japanese journal of infectious diseases, 2013, Volume: 66, Issue:4

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lipids; Male; Middle Aged; Prospective Studies; Pyrrolidinones; Raltegravir Potassium; Republic of Korea; Retrospective Studies; Treatment Outcome; Viral Load; Young Adult; Zidovudine

2013
[Evaluation of tolerance of zidovudine-lamivudine-nevirapine combination in HIV 1 patients in Fann Teaching Hospital in Dakar].
    Bulletin de la Societe de pathologie exotique (1990), 2013, Volume: 106, Issue:4

    Topics: Adult; Anti-HIV Agents; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Hospitals, Teaching; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Senegal; Zidovudine

2013
Commentary: The place of tenofovir disoproxil fumarate in pediatric antiretroviral therapy.
    The Pediatric infectious disease journal, 2015, Volume: 34, Issue:4

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Utilization; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; Stavudine; Zidovudine

2015
Adverse Drug Reactions and Clinical Outcomes in Patients Initiated on Antiretroviral Therapy: A Prospective Cohort Study From Ethiopia.
    Drug safety, 2015, Volume: 38, Issue:7

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Anti-Retroviral Agents; Body Mass Index; Chi-Square Distribution; Drug-Related Side Effects and Adverse Reactions; Ethiopia; Female; Humans; Incidence; Logistic Models; Male; Medication Adherence; Odds Ratio; Pharmacovigilance; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors; Unemployment; Weight Gain; Zidovudine

2015
Antiretroviral exposure during pregnancy and adverse outcomes in HIV-exposed uninfected infants and children using a trigger-based design.
    AIDS (London, England), 2016, Jan-02, Volume: 30, Issue:1

    Topics: Adult; Anti-Retroviral Agents; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Infant, Newborn; Male; Maternal Exposure; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; United States; Young Adult; Zidovudine

2016
Safety of antiretroviral drug therapy in Jamaican children with HIV/AIDS.
    The West Indian medical journal, 2008, Volume: 57, Issue:3

    Topics: Adolescent; Adult; Anti-HIV Agents; Anti-Retroviral Agents; Child; Child Welfare; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Infant, Newborn; Jamaica; Male; Prospective Studies; Surveys and Questionnaires; Young Adult; Zidovudine

2008
Second-line treatment in the Malawi antiretroviral programme: high early mortality, but good outcomes in survivors, despite extensive drug resistance at baseline.
    HIV medicine, 2010, Volume: 11, Issue:8

    Topics: Adenine; Adolescent; Adult; Anti-Retroviral Agents; Body Mass Index; CD4 Lymphocyte Count; Developing Countries; Drug Resistance, Viral; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Genotype; HIV Infections; HIV-1; Humans; Malawi; Male; Medication Adherence; Middle Aged; National Health Programs; Organophosphonates; Prospective Studies; RNA, Viral; Statistics as Topic; Tenofovir; Treatment Failure; Tuberculosis; Urban Population; Viral Load; Zidovudine

2010
Adverse drug reactions to antiretroviral therapy (ARVs): incidence, type and risk factors in Nigeria.
    BMC clinical pharmacology, 2012, Feb-27, Volume: 12

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Exanthema; Female; HIV Infections; Humans; Incidence; Lamivudine; Male; Middle Aged; Nevirapine; Nigeria; Organophosphonates; Pain; Retrospective Studies; Risk Factors; Stavudine; Tenofovir; Zidovudine

2012
Adverse events caused by drug interactions involving glucuronoconjugates of zidovudine, valproic acid and lamotrigine, and analysis of how such potential events are discussed in package inserts of Japan, UK and USA.
    Journal of clinical pharmacy and therapeutics, 2007, Volume: 32, Issue:2

    Topics: Area Under Curve; Communication; Disclosure; Drug Combinations; Drug Interactions; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Glucuronates; Half-Life; Humans; Japan; Lamotrigine; Triazines; United Kingdom; United States; Valproic Acid; Zidovudine

2007
HIV, women, and access to clinical trials: tort liability and lessons from DES.
    Duke journal of gender law & policy, 1998,Spring, Volume: 5, Issue:1

    Topics: Clinical Trials as Topic; Diethylstilbestrol; Disclosure; Drug-Related Side Effects and Adverse Reactions; Federal Government; Female; Government; Government Regulation; Hazardous Substances; HIV Seropositivity; Human Experimentation; Humans; Informed Consent; Jurisprudence; Liability, Legal; Malpractice; Occupational Exposure; Patient Selection; Pregnancy; Pregnant Women; Prejudice; Radiation; Research Subjects; Risk; Risk Assessment; Social Control, Formal; United States; Women; Women's Health; Wounds and Injuries; Zidovudine

1998
[India: an expensive and dangerous drug].
    Sygeplejersken, 1992, Dec-16, Volume: 92, Issue:51

    Topics: Acquired Immunodeficiency Syndrome; Drug Costs; Drug-Related Side Effects and Adverse Reactions; Health Care Costs; Humans; India; Pharmaceutical Preparations; Zidovudine

1992