zidovudine has been researched along with Acute Liver Injury, Drug-Induced in 39 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (2.56) | 18.7374 |
1990's | 11 (28.21) | 18.2507 |
2000's | 10 (25.64) | 29.6817 |
2010's | 16 (41.03) | 24.3611 |
2020's | 1 (2.56) | 2.80 |
Authors | Studies |
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Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Abongwa, LE; Bella, S; Charles, F; Domkam, I; Emmanuel, N; Eyongetah, M; Jude, B; Moungang, EC; Mua, FH; Ngum, V; Nyamache, AK; Okemo, P; Tamboh, TC; Torimiro, J | 1 |
Chen, X; Fairley, CK; He, J; Jing, J; Mao, L; Sasadeusz, J; Su, S; Wei, X; Zeng, H; Zhang, L | 1 |
Davis, K; Fabian, E; Greenhaw, J; Groeters, S; Herold, M; Kamp, H; Looser, R; Marxfeld, H; Mattes, W; Mellert, W; Moeller, N; Montoya-Parra, G; Prokoudine, A; Strauss, V; van Ravenzwaay, B; Walk, T | 1 |
Bekolo, CE; Bekoule, PS; Djidjou, H; Kollo, B; Sonkoue, C | 1 |
Bhavani, G; Ezhilarasan, D; Jesudas, B; Karthikeyan, S; Raghu, R | 1 |
Karthikeyan, S; Raghu, R | 1 |
Bazarbachi, A; de Thé, H; El Hajj, H; Farid, R; Hatoum, H; Hermine, O; Kchour, G; Kooshyar, MM; Mahmoudi, M; Maleki, M; Rafatpanah, H; Rahimi, H; Rezaee, SA; Shirdel, A; Tarhini, M; Wattel, E; Yazdi, MT | 1 |
Adesina, EA; Agbaje, EO; Akintonwa, A; Awodele, O | 1 |
Brunet, C; Bui, E; De Saint Martin, L; Jovelin, T; Le Moal, G; Perfezou, P; Raffi, F; Reliquet, V; Venisse, N; Winer, N | 1 |
Agbaji, O; Ekong, E; Graham, C; Hawkins, C; Idoko, J; Kanki, P; Meloni, S; Muazu, M; Murphy, R; Nimzing, L; Sankalé, JL; Thio, CL | 1 |
Bouhour, D; Dumouchel-Champagne, H; Durupt, F; Ferry, T; Granier, P | 1 |
Girault, V | 1 |
Bentley, AT; Lynx, MD; McKee, EE | 1 |
Abdoulaye, D; André, C; André, E; Bernard, L; Sandrine, PF; Sylvie, A | 1 |
Ali, IY; Gaikwad, AB; Gupta, J; Tamta, A; Tikoo, K | 1 |
Amato, DA; DeGruttola, V; Eyster, ME; Gjerset, GF; Ho, M; Kessler, CM; LoFaro, ML; Parenti, DM; Ragni, MV; Van Der Horst, C | 1 |
Ameer, B | 1 |
Chapnick, EK; Gradon, JD; Sepkowitz, DV | 2 |
Acosta, EP; Henry, K; Jochimsen, E | 1 |
Borucki, MJ; Haque, AK; Olano, JP; Wen, JW | 1 |
Abad, M; Alonso, MJ; Corcuera, T; Gómez, F; López-Bravo, A; Muñoz, E; Picazo, A; Roldán, M | 1 |
Aoki, M; Genka, I; Kikuchi, Y; Oka, S; Tachikawa, N; Teruya, K; Yamaguchi, M; Yamamoto, Y; Yasuoka, A; Yasuoka, C | 1 |
Koranyi, K; Nahata, MC; Pai, VB | 1 |
Espiridião SKulay, L; Mamede, JA; Mora, OA; Oliveira-Filho, RM; Simo s, MJ | 1 |
Carr, A; Mallon, P; Morey, A; Thorburn, DR; Williams, D | 1 |
Goetz, MB; Shriner, K | 1 |
Barker, SM; Chen, SC; Cunningham, AL; Mitchell, DH; O'Neill, P; Stevens, SM | 1 |
Bozzette, S; Connor, JD; Dieterich, D; Hochster, H; Liebes, L; Pettinelli, C; Reichman, RC; Sonke, RL; Spector, SA; Valentine, F | 1 |
Braffman, MN; Dubin, G | 1 |
2 review(s) available for zidovudine and Acute Liver Injury, Drug-Induced
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[The treatment of HIV infection].
Topics: Adenine; Anti-Retroviral Agents; Carbamates; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Therapy, Combination; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Organophosphates; Organophosphonates; Risk Factors; Sulfonamides; Tenofovir; Zidovudine | 2005 |
4 trial(s) available for zidovudine and Acute Liver Injury, Drug-Induced
Article | Year |
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Phase 2 study of the efficacy and safety of the combination of arsenic trioxide, interferon alpha, and zidovudine in newly diagnosed chronic adult T-cell leukemia/lymphoma (ATL).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Chemical and Drug Induced Liver Injury; Drug Eruptions; Drug Synergism; Female; Gastrointestinal Diseases; Hematologic Diseases; Human T-lymphotropic virus 1; Humans; Interferon-alpha; Leukemia-Lymphoma, Adult T-Cell; Male; Middle Aged; Oxides; Proviruses; Remission Induction; Viral Load; Zidovudine | 2009 |
Effectiveness and safety of saquinavir/ritonavir in HIV-infected pregnant women: INEMA cohort.
Topics: Adult; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Cohort Studies; Delivery, Obstetric; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; HIV-2; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prospective Studies; Ritonavir; Saquinavir; Treatment Outcome; Viral Load; Viremia; Young Adult; Zidovudine | 2012 |
Randomized study of didanosine monotherapy and combination therapy with zidovudine in hemophilic and nonhemophilic subjects with asymptomatic human immunodeficiency virus-1 infection. AIDS Clinical Trial Groups.
Topics: Adult; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Didanosine; Drug Therapy, Combination; Female; Hemophilia A; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Male; Safety; Treatment Outcome; Viremia; Zidovudine | 1995 |
Toxicity of combined ganciclovir and zidovudine for cytomegalovirus disease associated with AIDS. An AIDS Clinical Trials Group Study.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Anemia; Chemical and Drug Induced Liver Injury; Cytomegalovirus Infections; Drug Therapy, Combination; Female; Ganciclovir; Humans; Leukopenia; Male; Middle Aged; Multicenter Studies as Topic; Neutropenia; Prospective Studies; Time Factors; Vomiting; Zidovudine | 1990 |
33 other study(ies) available for zidovudine and Acute Liver Injury, Drug-Induced
Article | Year |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Risk factors of severe hepatotoxicity among HIV-1 infected individuals initiated on highly active antiretroviral therapy in the Northwest Region of Cameroon.
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cameroon; Chemical and Drug Induced Liver Injury; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Risk Factors; Young Adult; Zidovudine | 2022 |
HBV, HCV, and HBV/HCV co-infection among HIV-positive patients in Hunan province, China: Regimen selection, hepatotoxicity, and antiretroviral therapy outcome.
Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Cohort Studies; Coinfection; Cyclopropanes; Female; Hepatitis B; Hepatitis C; HIV; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Retrospective Studies; Treatment Outcome; Viral Load; Zidovudine | 2018 |
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma.
Topics: Animals; Atropine; Captopril; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Flutamide; Lamivudine; Liver; Male; Mannitol; Metabolomics; Methotrexate; Neomycin; Oxidative Stress; Phenytoin; Piperazines; Propylthiouracil; Rats; Rats, Wistar; Streptomycin; Triazoles; Valproic Acid; Vancomycin; Zidovudine | 2014 |
Evaluating the utility of early laboratory monitoring of antiretroviral-induced haematological and hepatic toxicity in HIV-infected persons in Cameroon.
Topics: Adult; Anemia; Anti-HIV Agents; Cameroon; Chemical and Drug Induced Liver Injury; Early Diagnosis; Female; HIV Infections; Humans; Male; Middle Aged; Prevalence; Retrospective Studies; Stavudine; Zidovudine | 2014 |
Silibinin mitigates zidovudine-induced hepatocellular degenerative changes, oxidative stress and hyperlipidaemia in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Anti-HIV Agents; Catalase; Chemical and Drug Induced Liver Injury; Fatty Acids, Nonesterified; Female; Hyperlipidemias; Lipid Peroxidation; Liver; Male; Oxidative Stress; Protective Agents; Rats, Wistar; Silybin; Silymarin; Zidovudine | 2015 |
Zidovudine and isoniazid induced liver toxicity and oxidative stress: Evaluation of mitigating properties of silibinin.
Topics: Animals; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury; Drug Synergism; Female; Isoniazid; Liver Function Tests; Male; Oxidative Stress; Rats, Wistar; Silybin; Silymarin; Zidovudine | 2016 |
Hepatoprotective role of neutrosecR on hepatic damage induced by combination of zidovudine and combined anti-tuberculous agents in rats.
Topics: Amino Acids; Animals; Anti-HIV Agents; Antioxidants; Antitubercular Agents; Catalase; Chemical and Drug Induced Liver Injury; Dietary Supplements; Drug Combinations; Drug Therapy, Combination; Liver; Liver Function Tests; Protective Agents; Rats; Vitamins; Zidovudine | 2011 |
Impact of hepatitis C virus on HIV response to antiretroviral therapy in Nigeria.
Topics: Adult; Alanine Transaminase; Alkynes; Anti-Retroviral Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Coinfection; Cyclopropanes; Deoxycytidine; Drug Combinations; Drug Therapy, Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Nevirapine; Nigeria; Organophosphorus Compounds; RNA, Viral; Stavudine; Zidovudine | 2013 |
[Hypersensitive reaction to abacavir or syphilitic hepatitis?].
Topics: Adult; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Ethylenediamines; HIV Seropositivity; Humans; Lamivudine; Male; Syphilis; Zidovudine | 2003 |
3'-Azido-3'-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity.
Topics: Animals; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; In Vitro Techniques; Kinetics; Liver Diseases; Mitochondria, Liver; Phosphorylation; Rats; Rats, Sprague-Dawley; Thymidine; Zidovudine | 2006 |
Nodular regenerative hyperplasia: a new serious antiretroviral drugs side effect?
Topics: Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Chemical and Drug Induced Liver Injury; Didanosine; Female; HIV Infections; HIV-1; Humans; Hyperplasia; Liver; Liver Diseases; Liver Regeneration; Middle Aged; Nevirapine; Zidovudine | 2007 |
Tannic acid prevents azidothymidine (AZT) induced hepatotoxicity and genotoxicity along with change in expression of PARG and histone H3 acetylation.
Topics: Acetylation; Alanine Transaminase; Alkaline Phosphatase; Animals; Anti-HIV Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; DNA Damage; Glycoside Hydrolases; Histones; Liver; Liver Diseases; Malondialdehyde; Mice; Micronucleus Tests; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Tannins; Zidovudine | 2008 |
Acetaminophen hepatotoxicity augmented by zidovudine.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Drug Synergism; Humans; Rats; Zidovudine | 1993 |
Immunosuppressive effect of zidovudine.
Topics: Chemical and Drug Induced Liver Injury; Humans; Zidovudine | 1993 |
Hepatotoxicity and rash associated with zidovudine and zalcitabine chemoprophylaxis.
Topics: Chemical and Drug Induced Liver Injury; Erythema; Female; HIV Infections; Humans; Middle Aged; Zalcitabine; Zidovudine | 1996 |
Massive hepatic steatosis and lactic acidosis in a patient with AIDS who was receiving zidovudine.
Topics: Acidosis, Lactic; Acquired Immunodeficiency Syndrome; Adult; Alanine Transaminase; Bilirubin; Chemical and Drug Induced Liver Injury; Fat Necrosis; Fatal Outcome; Female; Humans; L-Lactate Dehydrogenase; Liver Diseases; Zidovudine | 1995 |
Hepatic Morphological alterations induced by zidovudine (ZDV) in an experimental model.
Topics: Animals; Chemical and Drug Induced Liver Injury; Liver; Liver Diseases; Microscopy, Electron; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Time Factors; Zidovudine | 1996 |
Mitigation of hepato-cellular injury caused by HAART with glycyrrhizin compound in patients co-infected with HIV and HCV.
Topics: Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug Combinations; Drug Therapy, Combination; Glycine; Glycyrrhetinic Acid; Hemophilia A; Hepatitis C; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1999 |
Acute hepatitis and bleeding possibly induced by zidovudine and ritonavir in an infant with HIV infection.
Topics: Acute Disease; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Fatal Outcome; Hemorrhage; HIV Infections; Humans; Infant; Male; Ritonavir; Zidovudine | 2000 |
Serious adverse events attributed to nevirapine regimens for postexposure prophylaxis after HIV exposures--worldwide, 1997-2000.
Topics: Adult; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; HIV Infections; Humans; Lamivudine; Liver Failure; Male; Nevirapine; Occupational Exposure; Reverse Transcriptase Inhibitors; Rhabdomyolysis; Zidovudine | 2001 |
Hepatic and renal effects of azidothymidine and acyclovir on pregnant rats.
Topics: Abortion, Spontaneous; Acyclovir; Animals; Antiviral Agents; Chemical and Drug Induced Liver Injury; Drug Synergism; Female; Kidney; Kidney Diseases; Liver; Liver Diseases; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; Zidovudine | 2000 |
Fatal portal hypertension, liver failure, and mitochondrial dysfunction after HIV-1 nucleoside analogue-induced hepatitis and lactic acidaemia.
Topics: Acute Disease; Aged; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Didanosine; Fatal Outcome; Fatty Liver; HIV Infections; HIV-1; Humans; Hypertension, Portal; Male; Mitochondria, Liver; Stavudine; Zidovudine | 2001 |
Zidovudine-induced hepatitis.
Topics: Adult; Chemical and Drug Induced Liver Injury; HIV Infections; Humans; Male; Zidovudine | 1992 |
Severe hepatotoxicity in a patient receiving both acetaminophen and zidovudine.
Topics: Acetaminophen; Acquired Immunodeficiency Syndrome; Adult; Chemical and Drug Induced Liver Injury; Humans; Liver; Male; Zidovudine | 1992 |
Concurrent zidovudine-induced myopathy and hepatoxicity in patients treated for human immunodeficiency virus (HIV) infection.
Topics: Adult; Chemical and Drug Induced Liver Injury; HIV Infections; Humans; Male; Muscular Diseases; Zidovudine | 1992 |
Zidovudine-induced hepatotoxicity.
Topics: Adult; Chemical and Drug Induced Liver Injury; Cholestasis; Humans; Liver Function Tests; Male; Zidovudine | 1989 |