zerumbone has been researched along with Edema* in 1 studies
1 other study(ies) available for zerumbone and Edema
Article | Year |
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Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice.
The anti-inflammatory activity of zerumbone (1), a natural cyclic sesquiterpene isolated from Zingiber zerumbet Smith was investigated using carrageenan-induced paw edema and cotton pellet-induced granuloma tissue formation test in mice. It was demonstrated that intraperitoneal administration of 1 at a dose of 5, 10, 50 and 100 mg/kg produced significant dose-dependent inhibition of paw edema induced by carrageenan. It was also demonstrated that 1 at similar doses significantly suppressed granulomatous tissue formation in cotton pellet-induced granuloma test. Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Edema; Gossypium; Granuloma; Inflammation; Male; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Rhizome; Sesquiterpenes; Zingiberaceae | 2010 |