zerumbone has been researched along with Abdominal-Pain* in 1 studies
1 other study(ies) available for zerumbone and Abdominal-Pain
Article | Year |
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Preliminary analysis of the antinociceptive activity of zerumbone.
We have investigated the antinociceptive activity of zerumbone (1), a natural cyclic sesquiterpene isolated from Zingiber zerumbet Smith, in acetic acid-induced abdominal writhing test and hot plate test in mice. 1 given by intraperitoneal route produced significant dose-dependent antinociceptive effect in all the test models used. In addition, the antinociceptive effect of 1 in the hot plate test was reversed by the non-selective opioid receptor antagonist naloxone, suggesting that the opioid system is involved in its analgesic mechanism of action. Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Dose-Response Relationship, Drug; Hot Temperature; Male; Mice; Mice, Inbred BALB C; Naloxone; Narcotic Antagonists; Phytotherapy; Plant Extracts; Sesquiterpenes; Zingiberaceae | 2009 |