Compounds > zd 7288
Page last updated: 2024-09-03

zd 7288 and Pain

zd 7288 has been researched along with Pain in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, AQ; Chen, Y; Lin, C; Liu, CY; Lu, DL; Tang, Y1
Duan, J; Hu, S; Lv, X; Niu, C; Tan, C; Wang, S; Wang, W; Wang, X; Wu, Y; Xing, J; Yang, J; Zhang, M1
Chen, CC; Cheng, JK; Huang, YJ; Lin, CF; Lin, CS; Tsaur, ML1
Acosta, C; Djouhri, L; Gao, LL; Harper, AA; Lawson, SN; McMullan, S1
Bie, B; Pan, ZZ; Peng, Y; Zhang, Y1
Ao, H; Brown, SM; Chang, L; Chaplan, SR; Dubin, AE; Higuera, ES; Lee, DH; Luo, L1
Hogan, QH; Poroli, M1
Jiang, YQ; Sun, Q; Tu, HY; Wan, Y1

Reviews

1 review(s) available for zd 7288 and Pain

ArticleYear
Characteristics of HCN channels and their participation in neuropathic pain.
    Neurochemical research, 2008, Volume: 33, Issue:10

    Topics: Animals; Axons; Benzazepines; Cyclic Nucleotide-Gated Cation Channels; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ivabradine; Neural Conduction; Nociceptors; Pain; Potassium Channels; Pyrimidines; Synaptic Transmission

2008

Other Studies

7 other study(ies) available for zd 7288 and Pain

ArticleYear
ZD 7288, an HCN channel blocker, attenuates chronic visceral pain in irritable bowel syndrome-like rats.
    World journal of gastroenterology, 2014, Feb-28, Volume: 20, Issue:8

    Topics: Analgesics; Animals; Cardiotonic Agents; Chronic Pain; Colon; Disease Models, Animal; Electromyography; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Irritable Bowel Syndrome; Male; Muscle, Skeletal; Pain; Pain Threshold; Pyrimidines; Rats; Rats, Sprague-Dawley; Visceral Pain

2014
A novel intrinsic analgesic mechanism: the enhancement of the conduction failure along polymodal nociceptive C-fibers.
    Pain, 2016, Volume: 157, Issue:10

    Topics: Animals; Biophysics; Calcium; Disease Models, Animal; Female; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Inflammation; Membrane Potentials; Nerve Fibers, Unmyelinated; Neural Conduction; Neurons; Pain; Pain Threshold; Patch-Clamp Techniques; Pyrimidines; Rats; Rats, Sprague-Dawley

2016
Intrathecal gabapentin does not act as a hyperpolarization-activated cyclic nucleotide-gated channel activator in the rat formalin test.
    European journal of anaesthesiology, 2009, Volume: 26, Issue:10

    Topics: Amines; Analgesics; Animals; Cardiotonic Agents; Cyclic Nucleotide-Gated Cation Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Injections, Spinal; Male; Pain; Potassium Channels; Pyrimidines; Rats; Rats, Sprague-Dawley

2009
Expression and properties of hyperpolarization-activated current in rat dorsal root ganglion neurons with known sensory function.
    The Journal of physiology, 2012, Oct-01, Volume: 590, Issue:19

    Topics: Action Potentials; Animals; Cyclic Nucleotide-Gated Cation Channels; Female; Ganglia, Spinal; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Nociceptors; Pain; Potassium Channels; Pyrimidines; Rats; Rats, Wistar

2012
cAMP-mediated mechanisms for pain sensitization during opioid withdrawal.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Apr-13, Volume: 25, Issue:15

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Animals, Newborn; Behavior, Animal; Blotting, Western; Colforsin; Cyclic AMP; Dose-Response Relationship, Radiation; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Imines; In Vitro Techniques; Isoquinolines; Male; Membrane Potentials; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Oxidoreductases; Pain; Pain Measurement; Patch-Clamp Techniques; Pyrimidines; Raphe Nuclei; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides

2005
Role of peripheral hyperpolarization-activated cyclic nucleotide-modulated channel pacemaker channels in acute and chronic pain models in the rat.
    Neuroscience, 2007, Feb-23, Volume: 144, Issue:4

    Topics: Acute Disease; Animals; Cardiovascular Agents; Chronic Disease; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Mechanoreceptors; Merkel Cells; Nociceptors; Pain; Peripheral Nerves; Potassium Channels; Pyrimidines; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Skin

2007
Hyperpolarization-activated current (I(h)) contributes to excitability of primary sensory neurons in rats.
    Brain research, 2008, May-01, Volume: 1207

    Topics: Animals; Behavior, Animal; Cardiotonic Agents; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Ganglia, Spinal; Ligation; Male; Membrane Potentials; Neurons, Afferent; Pain; Patch-Clamp Techniques; Pyrimidines; Rats; Rats, Sprague-Dawley

2008