Page last updated: 2024-09-03

zd 7288 and Nerve Pain

zd 7288 has been researched along with Nerve Pain in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (21.43)29.6817
2010's11 (78.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cao, JL; Deisseroth, K; Ding, HL; Guo, XY; Han, MH; Koo, JW; Li, C; Liu, D; Liu, H; Liu, MJ; Mouzon, E; Nestler, EJ; Qian, YL; Wang, L; Wang, XY; Yang, JX; Zachariou, V; Zhang, H; Zhang, S1
Fu, B; Huang, T; Liu, SJ; Wang, B; Wang, J; Weng, XC1
Fan, S; Jiang, F; Liu, X; Liu, Y; Mao, P; Sun, Y; Wei, X; Yan, H; Yang, L; Yao, K; Yuan, W; Zhang, S1
Mazo, I; Rivera-Arconada, I; Roza, C1
Cao, J; Wu, T; Zhang, LC1
Al Otaibi, M; Djouhri, L; Sathish, J; Smith, T1
Nevian, T; Santello, M1
Cordeiro Matos, S; Séguéla, P; Zhang, Z1
Chen, L; Ding, W; Mao, J; Shen, S; You, Z; Zhu, S1
Cui, J; Du, L; He, WJ; Ruan, HZ; Wang, SJ2
Brown, SM; Butler, MP; Chaplan, SR; Dubin, AE; Guo, HQ; Kuei, C; Lee, DH; Liu, C; Luo, L; Velumian, AA1
Han, JS; Sun, Q; Tu, HY; Wan, Y; Xing, GG1
Chang, L; Chaplan, SR; Lee, DH; Sorkin, LS1

Other Studies

14 other study(ies) available for zd 7288 and Nerve Pain

ArticleYear
Brain-Derived Neurotrophic Factor in the Mesolimbic Reward Circuitry Mediates Nociception in Chronic Neuropathic Pain.
    Biological psychiatry, 2017, Oct-15, Volume: 82, Issue:8

    Topics: Animals; Baclofen; Benzazepines; Brain-Derived Neurotrophic Factor; Cardiotonic Agents; Disease Models, Animal; Dopaminergic Neurons; Functional Laterality; GABA-B Receptor Agonists; Limbic System; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Neuralgia; Nociception; Pain Threshold; Proto-Oncogene Proteins c-fos; Pyrimidines; Reward

2017
[Effects of HCN2 in the development of peripheral neuropathic pain in rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2017, Apr-08, Volume: 33, Issue:4

    Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Neuralgia; Potassium Channels; Pyrimidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Nerves

2017
HCN channel antagonist ZD7288 ameliorates neuropathic pain and associated depression.
    Brain research, 2019, 08-15, Volume: 1717

    Topics: Animals; Brain; Cyclic Nucleotide-Gated Cation Channels; Depression; Depressive Disorder; GABAergic Neurons; Glutamate Decarboxylase; Hippocampus; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Neuralgia; Neurons; Pyrimidines; Rats; Rats, Inbred WKY; Thalamus

2019
Axotomy-induced changes in activity-dependent slowing in peripheral nerve fibres: role of hyperpolarization-activated/HCN channel current.
    European journal of pain (London, England), 2013, Volume: 17, Issue:9

    Topics: Animals; Axons; Axotomy; Electric Stimulation; Female; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Mice; Neural Conduction; Neuralgia; Peripheral Nerves; Pyrimidines

2013
[Neuropathic pain enhances expression of HCN2 channel in rat cerebrospinal fluid-contacting nucleus].
    Sheng li xue bao : [Acta physiologica Sinica], 2014, Jun-25, Volume: 66, Issue:3

    Topics: Animals; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Neuralgia; Neurons; Pain Threshold; Potassium Channels; Proto-Oncogene Proteins c-fos; Pyrimidines; Rats; Rats, Sprague-Dawley

2014
Increased expression of HCN2 channel protein in L4 dorsal root ganglion neurons following axotomy of L5- and inflammation of L4-spinal nerves in rats.
    Neuroscience, 2015, Jun-04, Volume: 295

    Topics: Amines; Animals; Axotomy; Cyclohexanecarboxylic Acids; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Lectins; Neuralgia; Pain Threshold; Pyrimidines; Radiculopathy; Rats; Rats, Wistar; Reaction Time; Spinal Nerves

2015
Dysfunction of cortical dendritic integration in neuropathic pain reversed by serotoninergic neuromodulation.
    Neuron, 2015, Apr-08, Volume: 86, Issue:1

    Topics: Animals; Cardiovascular Agents; Cerebral Cortex; Dendrites; Disease Models, Animal; Excitatory Postsynaptic Potentials; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Lysine; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Neuralgia; Neurons; Pain Measurement; Potassium Channels; Pyrimidines; Receptors, Serotonin; Serotonin; Serotonin Agents; Time Factors

2015
Peripheral Neuropathy Induces HCN Channel Dysfunction in Pyramidal Neurons of the Medial Prefrontal Cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Sep-23, Volume: 35, Issue:38

    Topics: Animals; Biophysical Phenomena; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Hyperalgesia; In Vitro Techniques; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Neuralgia; Pain Measurement; Pain Threshold; Prefrontal Cortex; Pyramidal Cells; Pyrimidines; Rats; Rats, Long-Evans; Sodium Channel Blockers; Synaptic Potentials; Tetrodotoxin

2015
Inhibition of HCN channel activity in the thalamus attenuates chronic pain in rats.
    Neuroscience letters, 2016, Sep-19, Volume: 631

    Topics: Animals; Arthritis, Experimental; Chronic Pain; Freund's Adjuvant; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Neuralgia; Nociception; Potassium Channels; Pyrimidines; Rats; Rats, Sprague-Dawley; Thalamus

2016
The role of HCN channels within the periaqueductal gray in neuropathic pain.
    Brain research, 2013, Mar-15, Volume: 1500

    Topics: Action Potentials; Animals; Cyclic Nucleotide-Gated Cation Channels; Excitatory Postsynaptic Potentials; Neuralgia; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Pyrimidines; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy

2013
Inhibition of HCN channels within the periaqueductal gray attenuates neuropathic pain in rats.
    Behavioral neuroscience, 2013, Volume: 127, Issue:2

    Topics: Animals; Cyclic Nucleotide-Gated Cation Channels; Hyperalgesia; Neuralgia; Pain Measurement; Periaqueductal Gray; Pyrimidines; Rats; Rats, Sprague-Dawley

2013
Neuronal hyperpolarization-activated pacemaker channels drive neuropathic pain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Feb-15, Volume: 23, Issue:4

    Topics: Action Potentials; Animals; Cell Line; Cell Membrane; Cells, Cultured; Cyclic Nucleotide-Gated Cation Channels; Electric Conductivity; Ganglia, Spinal; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Kinetics; Male; Nerve Tissue Proteins; Neuralgia; Neurons; Potassium Channels; Pyrimidines; Rats; Rats, Sprague-Dawley; RNA, Messenger

2003
Inhibition of hyperpolarization-activated current by ZD7288 suppresses ectopic discharges of injured dorsal root ganglion neurons in a rat model of neuropathic pain.
    Brain research, 2005, Jan-25, Volume: 1032, Issue:1-2

    Topics: Action Potentials; Animals; Cardiovascular Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Ganglia, Spinal; Male; Neural Inhibition; Neuralgia; Neurons; Pyrimidines; Rats; Rats, Sprague-Dawley; Time Factors

2005
Hyperpolarization-activated, cation-nonselective, cyclic nucleotide-modulated channel blockade alleviates mechanical allodynia and suppresses ectopic discharge in spinal nerve ligated rats.
    The journal of pain, 2005, Volume: 6, Issue:7

    Topics: Animals; Axotomy; Cardiovascular Agents; Cations; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Ion Channels; Ligation; Male; Nerve Fibers, Myelinated; Neuralgia; Neurons, Afferent; Pain Threshold; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Pyrimidines; Rats; Rats, Sprague-Dawley; Spinal Nerve Roots; Spinal Nerves

2005