zd 7288 has been researched along with Allodynia in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 13 (76.47) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, X; Mai, J; Xie, H; Yang, L; Zeng, X | 1 |
| Fu, B; Huang, T; Liu, SJ; Wang, B; Wang, J; Weng, XC | 1 |
| Fan, S; Jiang, F; Liu, X; Liu, Y; Mao, P; Sun, Y; Wei, X; Yan, H; Yang, L; Yao, K; Yuan, W; Zhang, S | 1 |
| Mazo, I; Rivera-Arconada, I; Roza, C | 1 |
| Chen, AQ; Chen, Y; Lin, C; Liu, CY; Lu, DL; Tang, Y | 1 |
| Dilley, A; Richards, N | 1 |
| Al Otaibi, M; Djouhri, L; Sathish, J; Smith, T | 1 |
| Cordeiro Matos, S; Séguéla, P; Zhang, Z | 1 |
| Chen, L; Mao, J; McCabe, MF; Mi, W; Shen, S; Sun, Y; Wang, S; Yang, J; Yang, L; You, Z; Zhang, S | 1 |
| Chen, L; Ding, W; Mao, J; Shen, S; You, Z; Zhu, S | 1 |
| Duan, J; Hu, S; Lv, X; Niu, C; Tan, C; Wang, S; Wang, W; Wang, X; Wu, Y; Xing, J; Yang, J; Zhang, M | 1 |
| Ono, H; Takasu, K; Tanabe, M | 1 |
| Hu, SJ; Li, HM; Song, XJ; Song, Y; Xie, RG; Xing, JL; Yue, ZF | 1 |
| Cui, J; Du, L; He, WJ; Ruan, HZ; Wang, SJ | 1 |
| Donnelly, DF; LaMotte, RH; Ma, C; Yao, H | 1 |
| Chang, L; Chaplan, SR; Lee, DH; Sorkin, LS | 1 |
| Ao, H; Brown, SM; Chang, L; Chaplan, SR; Dubin, AE; Higuera, ES; Lee, DH; Luo, L | 1 |
17 other study(ies) available for zd 7288 and Allodynia
| Article | Year |
|---|---|
Activation of CB1R alleviates central sensitization by regulating HCN2-pNR2B signaling in a chronic migraine rat model.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Central Nervous System Sensitization; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Migraine Disorders; Potassium Channels; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Cannabinoid; Receptors, N-Methyl-D-Aspartate | 2023 |
[Effects of HCN2 in the development of peripheral neuropathic pain in rats].
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Neuralgia; Potassium Channels; Pyrimidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Nerves | 2017 |
HCN channel antagonist ZD7288 ameliorates neuropathic pain and associated depression.
Topics: Animals; Brain; Cyclic Nucleotide-Gated Cation Channels; Depression; Depressive Disorder; GABAergic Neurons; Glutamate Decarboxylase; Hippocampus; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Neuralgia; Neurons; Pyrimidines; Rats; Rats, Inbred WKY; Thalamus | 2019 |
Axotomy-induced changes in activity-dependent slowing in peripheral nerve fibres: role of hyperpolarization-activated/HCN channel current.
Topics: Animals; Axons; Axotomy; Electric Stimulation; Female; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Mice; Neural Conduction; Neuralgia; Peripheral Nerves; Pyrimidines | 2013 |
ZD 7288, an HCN channel blocker, attenuates chronic visceral pain in irritable bowel syndrome-like rats.
Topics: Analgesics; Animals; Cardiotonic Agents; Chronic Pain; Colon; Disease Models, Animal; Electromyography; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Irritable Bowel Syndrome; Male; Muscle, Skeletal; Pain; Pain Threshold; Pyrimidines; Rats; Rats, Sprague-Dawley; Visceral Pain | 2014 |
Contribution of hyperpolarization-activated channels to heat hypersensitivity and ongoing activity in the neuritis model.
Topics: Action Potentials; Analysis of Variance; Animals; Cardiotonic Agents; Chi-Square Distribution; Functional Laterality; Ganglia, Spinal; Gene Expression Regulation; Hot Temperature; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Nerve Fibers; Neural Conduction; Neuritis; Pain Threshold; Pyrimidines; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells | 2015 |
Increased expression of HCN2 channel protein in L4 dorsal root ganglion neurons following axotomy of L5- and inflammation of L4-spinal nerves in rats.
Topics: Amines; Animals; Axotomy; Cyclohexanecarboxylic Acids; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Lectins; Neuralgia; Pain Threshold; Pyrimidines; Radiculopathy; Rats; Rats, Wistar; Reaction Time; Spinal Nerves | 2015 |
Peripheral Neuropathy Induces HCN Channel Dysfunction in Pyramidal Neurons of the Medial Prefrontal Cortex.
Topics: Animals; Biophysical Phenomena; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Hyperalgesia; In Vitro Techniques; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Neuralgia; Pain Measurement; Pain Threshold; Prefrontal Cortex; Pyramidal Cells; Pyrimidines; Rats; Rats, Long-Evans; Sodium Channel Blockers; Synaptic Potentials; Tetrodotoxin | 2015 |
Neuropeptide S modulates the amygdaloidal HCN activities (Ih) in rats: Implication in chronic pain.
Topics: Amygdala; Animals; Chronic Pain; gamma-Aminobutyric Acid; Glutamic Acid; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Interneurons; Male; MAP Kinase Signaling System; Neuropeptides; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Pyrimidines; Rats; Rats, Sprague-Dawley; Tachykinins | 2016 |
Inhibition of HCN channel activity in the thalamus attenuates chronic pain in rats.
Topics: Animals; Arthritis, Experimental; Chronic Pain; Freund's Adjuvant; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Neuralgia; Nociception; Potassium Channels; Pyrimidines; Rats; Rats, Sprague-Dawley; Thalamus | 2016 |
A novel intrinsic analgesic mechanism: the enhancement of the conduction failure along polymodal nociceptive C-fibers.
Topics: Animals; Biophysics; Calcium; Disease Models, Animal; Female; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Inflammation; Membrane Potentials; Nerve Fibers, Unmyelinated; Neural Conduction; Neurons; Pain; Pain Threshold; Patch-Clamp Techniques; Pyrimidines; Rats; Rats, Sprague-Dawley | 2016 |
Spinal hyperpolarization-activated cyclic nucleotide-gated cation channels at primary afferent terminals contribute to chronic pain.
Topics: Animals; Cardiotonic Agents; Chronic Disease; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Hyperalgesia; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Neurologic Mutants; Nerve Fibers; Pain Measurement; Patch-Clamp Techniques; Presynaptic Terminals; Pyrimidines; Sciatica; Sodium Channel Blockers; Spinal Cord; Tetrodotoxin | 2010 |
Evoked bursting in injured Aβ dorsal root ganglion neurons: a mechanism underlying tactile allodynia.
Topics: Action Potentials; Animals; Biophysical Phenomena; Biophysics; Cardiovascular Agents; Chi-Square Distribution; Disease Models, Animal; Double-Blind Method; Elapid Venoms; Electric Stimulation; Female; Fourier Analysis; Ganglia, Spinal; Hyperalgesia; Male; Patch-Clamp Techniques; Pyrimidines; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Sodium Channel Blockers; Spinal Cord Compression; Tetrodotoxin; Time Factors | 2012 |
Inhibition of HCN channels within the periaqueductal gray attenuates neuropathic pain in rats.
Topics: Animals; Cyclic Nucleotide-Gated Cation Channels; Hyperalgesia; Neuralgia; Pain Measurement; Periaqueductal Gray; Pyrimidines; Rats; Rats, Sprague-Dawley | 2013 |
Upregulation of the hyperpolarization-activated cation current after chronic compression of the dorsal root ganglion.
Topics: Animals; Cell Separation; Cell Size; Cesium; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Electric Stimulation; Electrophysiology; Female; Ganglia, Spinal; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; In Vitro Techniques; Ion Channels; Membrane Potentials; Models, Neurological; Nerve Compression Syndromes; Neurons; Patch-Clamp Techniques; Potassium Channels; Pyrimidines; Rats; Rats, Sprague-Dawley | 2003 |
Hyperpolarization-activated, cation-nonselective, cyclic nucleotide-modulated channel blockade alleviates mechanical allodynia and suppresses ectopic discharge in spinal nerve ligated rats.
Topics: Animals; Axotomy; Cardiovascular Agents; Cations; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Ion Channels; Ligation; Male; Nerve Fibers, Myelinated; Neuralgia; Neurons, Afferent; Pain Threshold; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Pyrimidines; Rats; Rats, Sprague-Dawley; Spinal Nerve Roots; Spinal Nerves | 2005 |
Role of peripheral hyperpolarization-activated cyclic nucleotide-modulated channel pacemaker channels in acute and chronic pain models in the rat.
Topics: Acute Disease; Animals; Cardiovascular Agents; Chronic Disease; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Mechanoreceptors; Merkel Cells; Nociceptors; Pain; Peripheral Nerves; Potassium Channels; Pyrimidines; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Skin | 2007 |