zd 7288 has been researched along with Absence Seizure Disorder in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aydın, B; Çarçak, N; Onat, F; Yavuz, M | 1 |
| Çarçak, N; Chan, CS; Crunelli, V; David, F; Di Giovanni, G; Furdan, S; Gould, T; Hernández, VM; Lőrincz, ML; Mészáros, Á; Onat, F | 1 |
| Bajorat, R; Bräuer, AU; Deisz, RA; Kole, MH; Nitsch, R; Pahnke, J; Rolfs, A; Strauss, U | 1 |
| Abrahamczik, C; Budde, T; Caputi, L; Kanyshkova, T; Munsch, T; Pape, HC; Staak, R | 1 |
| Bräuer, AU; Schridde, U; Strauss, U; van Luijtelaar, G | 1 |
5 other study(ies) available for zd 7288 and Absence Seizure Disorder
| Article | Year |
|---|---|
Decreased Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2 Activity in a Rat Model of Absence Epilepsy and the Effect of ZD7288, an Ih Inhibitor, on the Spike-and-Wave Discharges.
Topics: Animals; Electroencephalography; Epilepsy, Absence; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Potassium Channels; Pyrimidines; Rats; Rats, Wistar | 2022 |
Suppression of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Function in Thalamocortical Neurons Prevents Genetically Determined and Pharmacologically Induced Absence Seizures.
Topics: Animals; Cerebral Cortex; Epilepsy, Absence; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Mice; Neurons; Pyrimidines; Rats; Ventral Thalamic Nuclei | 2018 |
An impaired neocortical Ih is associated with enhanced excitability and absence epilepsy.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blotting, Western; Brain; Disease Models, Animal; Dose-Response Relationship, Radiation; Drug Interactions; Electric Impedance; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Immunohistochemistry; In Situ Hybridization; In Vitro Techniques; Ion Channel Gating; Ion Channels; Male; Membrane Potentials; Neocortex; Nerve Tissue Proteins; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Pyrimidines; Rats; Rats, Inbred Strains; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Species Specificity | 2004 |
Impaired regulation of thalamic pacemaker channels through an imbalance of subunit expression in absence epilepsy.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adenine; Animals; Blotting, Northern; Cerebral Cortex; Cesium; Chlorides; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Electroencephalography; Enzyme Inhibitors; Epilepsy, Absence; Female; Gene Expression Regulation; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Immunohistochemistry; In Situ Hybridization; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Microinjections; Neurons; Patch-Clamp Techniques; Potassium Channels; Protein Isoforms; Pyrimidines; Rats; Rats, Mutant Strains; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thalamus | 2005 |
Environmental manipulations early in development alter seizure activity, Ih and HCN1 protein expression later in life.
Topics: Animals; Animals, Newborn; Behavior, Animal; Cyclic Nucleotide-Gated Cation Channels; Electroencephalography; Environment; Epilepsy, Absence; Female; Handling, Psychological; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Pregnancy; Pyrimidines; Random Allocation; Rats; Rats, Inbred Strains; Rats, Wistar; Seizures; Somatosensory Cortex | 2006 |