zardaverine has been researched along with Muscle Contraction in 4 studies
zardaverine: structure given in first source
zardaverine : A pyridazinone derivative in which pyridazin-3(2H)-one is substituted at C-6 with a 4-(difluoromethoxy)-3-methoxyphenyl group. It is a phosphodiesterase inhibitor, selective for PDE3 and 4.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pre-treatment with motapizone, RP73401, rolipram or the methylxanthine adenosine receptor antagonist, 8-phenyltheophylline, did not significantly decrease responses to either allergen or LTC(4)." | 1.31 | The effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C(4)-induced contractions in passively sensitized human airways. ( Branscheid, D; Dent, G; Magnussen, H; Rabe, KF; Rühlmann, E; Schmidt, DT; Watson, N, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rogliani, P | 1 |
| Calzetta, L | 1 |
| Capuani, B | 1 |
| Facciolo, F | 1 |
| Cazzola, M | 1 |
| Lauro, D | 1 |
| Matera, MG | 1 |
| Rabe, KF | 2 |
| Tenor, H | 1 |
| Dent, G | 2 |
| Schudt, C | 1 |
| Nakashima, M | 1 |
| Magnussen, H | 2 |
| Schmidt, DT | 1 |
| Watson, N | 1 |
| Rühlmann, E | 1 |
| Branscheid, D | 1 |
| Spicuzza, L | 1 |
| Belvisi, MG | 1 |
| Birrell, MA | 1 |
| Barnes, PJ | 1 |
| Hele, DJ | 1 |
| Giembycz, MA | 1 |
4 other studies available for zardaverine and Muscle Contraction
| Article | Year |
|---|---|
Glucagon-Like Peptide 1 Receptor: A Novel Pharmacological Target for Treating Human Bronchial Hyperresponsiveness.
Topics: Adenylyl Cyclases; Bronchial Hyperreactivity; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Exen | 2016 |
Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Antihypertensive Agents; Carbachol; Colforsin; Cytosol; Di | 1994 |
The effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C(4)-induced contractions in passively sensitized human airways.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Antigens, Dermatophagoides; Benzam | 2000 |
Evidence that the anti-spasmogenic effect of the beta-adrenoceptor agonist, isoprenaline, on guinea-pig trachealis is not mediated by cyclic AMP-dependent protein kinase.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Ty | 2001 |