zardaverine has been researched along with Bronchial Diseases in 1 studies
zardaverine: structure given in first source
zardaverine : A pyridazinone derivative in which pyridazin-3(2H)-one is substituted at C-6 with a 4-(difluoromethoxy)-3-methoxyphenyl group. It is a phosphodiesterase inhibitor, selective for PDE3 and 4.
Bronchial Diseases: Diseases involving the BRONCHI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zardaverine is shown to inhibit selectively two out of five isoenzyme classes of phosphodiesterases, namely PDE III from human platelets and PDE IV from human polymorphonuclear leucocytes (PMN) with IC50 values of 0." | 2.38 | Zardaverine: a cyclic AMP specific PDE III/IV inhibitor. ( Beume, R; Eltze, M; Kilian, U; Schudt, C; Winder, S, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schudt, C | 1 |
| Winder, S | 1 |
| Eltze, M | 1 |
| Kilian, U | 1 |
| Beume, R | 1 |
1 review available for zardaverine and Bronchial Diseases
| Article | Year |
|---|---|
Zardaverine: a cyclic AMP specific PDE III/IV inhibitor.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Allergens; Animals; Bronchial Diseases; Eosinophilia; Humans; I | 1991 |