zardaverine has been researched along with Asthma in 2 studies
zardaverine: structure given in first source
zardaverine : A pyridazinone derivative in which pyridazin-3(2H)-one is substituted at C-6 with a 4-(difluoromethoxy)-3-methoxyphenyl group. It is a phosphodiesterase inhibitor, selective for PDE3 and 4.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zardaverine is a newly developed selective phosphodiesterase III and IV inhibitor." | 6.67 | Bronchodilatory effect of inhaled zardaverine, a phosphodiesterase III and IV inhibitor, in patients with asthma. ( Brunnée, T; Engelstätter, R; Kunkel, G; Steinijans, VW, 1992) |
| "Zardaverine is a newly developed selective phosphodiesterase III and IV inhibitor." | 2.67 | Bronchodilatory effect of inhaled zardaverine, a phosphodiesterase III and IV inhibitor, in patients with asthma. ( Brunnée, T; Engelstätter, R; Kunkel, G; Steinijans, VW, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kodimuthali, A | 1 |
| Jabaris, SS | 1 |
| Pal, M | 1 |
| Brunnée, T | 1 |
| Engelstätter, R | 1 |
| Steinijans, VW | 1 |
| Kunkel, G | 1 |
1 review available for zardaverine and Asthma
| Article | Year |
|---|---|
Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease.
Topics: Asthma; Humans; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pulmonary Disease, Chr | 2008 |
1 trial available for zardaverine and Asthma
| Article | Year |
|---|---|
Bronchodilatory effect of inhaled zardaverine, a phosphodiesterase III and IV inhibitor, in patients with asthma.
Topics: Administration, Inhalation; Adult; Asthma; Bronchi; Double-Blind Method; Drug Evaluation; Female; Fo | 1992 |