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zardaverine and Asthma

zardaverine has been researched along with Asthma in 2 studies

zardaverine: structure given in first source
zardaverine : A pyridazinone derivative in which pyridazin-3(2H)-one is substituted at C-6 with a 4-(difluoromethoxy)-3-methoxyphenyl group. It is a phosphodiesterase inhibitor, selective for PDE3 and 4.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Zardaverine is a newly developed selective phosphodiesterase III and IV inhibitor."6.67Bronchodilatory effect of inhaled zardaverine, a phosphodiesterase III and IV inhibitor, in patients with asthma. ( Brunnée, T; Engelstätter, R; Kunkel, G; Steinijans, VW, 1992)
"Zardaverine is a newly developed selective phosphodiesterase III and IV inhibitor."2.67Bronchodilatory effect of inhaled zardaverine, a phosphodiesterase III and IV inhibitor, in patients with asthma. ( Brunnée, T; Engelstätter, R; Kunkel, G; Steinijans, VW, 1992)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kodimuthali, A1
Jabaris, SS1
Pal, M1
Brunnée, T1
Engelstätter, R1
Steinijans, VW1
Kunkel, G1

Reviews

1 review available for zardaverine and Asthma

ArticleYear
Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease.
    Journal of medicinal chemistry, 2008, Sep-25, Volume: 51, Issue:18

    Topics: Asthma; Humans; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pulmonary Disease, Chr

2008

Trials

1 trial available for zardaverine and Asthma

ArticleYear
Bronchodilatory effect of inhaled zardaverine, a phosphodiesterase III and IV inhibitor, in patients with asthma.
    The European respiratory journal, 1992, Volume: 5, Issue:8

    Topics: Administration, Inhalation; Adult; Asthma; Bronchi; Double-Blind Method; Drug Evaluation; Female; Fo

1992