zardaverine has been researched along with Airway Hyper-Responsiveness in 1 studies
zardaverine: structure given in first source
zardaverine : A pyridazinone derivative in which pyridazin-3(2H)-one is substituted at C-6 with a 4-(difluoromethoxy)-3-methoxyphenyl group. It is a phosphodiesterase inhibitor, selective for PDE3 and 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zardaverine is a novel phosphodiesterase III/IV inhibitor, developed as a potential therapeutic agent for asthma." | 1.29 | The effect of zardaverine, an inhibitor of phosphodiesterase isoenzymes III and IV, on endotoxin-induced airway changes in rats. ( Joos, GF; Kips, JC; Pauwels, RA; Peleman, RA, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kips, JC | 1 |
| Joos, GF | 1 |
| Peleman, RA | 1 |
| Pauwels, RA | 1 |
1 other study available for zardaverine and Airway Hyper-Responsiveness
| Article | Year |
|---|---|
The effect of zardaverine, an inhibitor of phosphodiesterase isoenzymes III and IV, on endotoxin-induced airway changes in rats.
Topics: Animals; Bronchoalveolar Lavage Fluid; Endotoxins; Escherichia coli; Inflammation; Isoenzymes; Lipop | 1993 |