zanamivir has been researched along with Grippe in 733 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 61 (8.32) | 18.2507 |
2000's | 280 (38.20) | 29.6817 |
2010's | 341 (46.52) | 24.3611 |
2020's | 51 (6.96) | 2.80 |
Authors | Studies |
---|---|
He, PL; Jiang, H; Li, J; Li, T; Liu, H; Tang, W; Zheng, M; Zhu, W; Zuo, JP | 1 |
Bailey, KW; Barnard, DL; Day, CW; Furuta, Y; Morrey, JD; Sidwell, RW; Smee, DF; Wong, MH | 1 |
Li, YH; Li, ZR; Liu, ZY; Shao, HY; Wang, B; Yi, H; You, XF; Zhao, LX | 1 |
Kakuta, M; Kubo, S; Nasu, H; Tokumitsu, A; Tomozawa, T; Yamashita, M | 1 |
Demmler-Harrison, GJ; Deyde, VM; Gubareva, LV; Klimov, AI; Okomo-Adhiambo, M; Sheu, TG; Xu, X | 1 |
Gubareva, LV; Klimov, AI; Mishin, VP; Nguyen, HT; Sheu, TG | 1 |
Cheng, YS; Fang, JM; Lee, PS; Liu, KC; Wang, SY; Wong, CH | 1 |
Cheng, TJ; Cheng, YS; Fang, JM; Huang, WI; Tsai, KC; Tseng, YC; Wang, PC; Wang, SY; Wong, CH | 1 |
Hao, C; Jiang, T; Wang, W; Yin, R; Yu, R; Zhang, L; Zhang, M | 1 |
Barrett, S; Hader, S; McKimm-Breschkin, JL; Pilling, PA; Streltsov, VA; Watts, AG | 1 |
Chen, F; Chen, Q; Dong, C; Han, X; Jin, M; Lan, K; Liang, J; Liu, X; Wu, S; Xu, Z; Yu, L; Yu, Y; Zhou, HB | 1 |
Feng, IJ; Hua, YM; Shih, MF; Su, HC; Tang, HJ | 1 |
Fujiwara, M; Hara, A; Hara, K; Kobayashi, C; Komeda, T; Miyazawa, S; Ogura, E; Urushihara, H; Yoshida, M | 1 |
Bandera, A; Castelli, V; Gori, A; Lombardi, A; Palomba, E; Renisi, G | 1 |
Jayabalan, T; Joshi, A; Miller, I; Oliver, A; Peppercorn, A; Wang-Jairaj, J; Zammit-Tabona, P | 1 |
Ding, P; Guo, Y; Li, Y; Ping, J; Suzuki, Y; Yu, M; Zhang, H; Zhang, Y; Zheng, Y | 1 |
Chan, KA; Fang, CT; Huang, CT; Su, CP | 1 |
Aziz, A; Barr, IG; Baz, M; Brown, SK; Tseng, YY | 1 |
Bando, T; Chong, Y; Ikematsu, H; Iwaki, N; Kashiwagi, S; Kawai, N; Shindo, S; Takasaki, Y; Tani, N | 1 |
Lai, CC; Wei, JCC | 1 |
Chang, R; Chen, HY; Hung, YM; Sun, CK | 1 |
Tian, Y; Wang, K; Zhang, H | 1 |
Dandekar, T; Sarukhanyan, E; Shanmugam, TA | 1 |
Aziz, A; Barr, IG; Baz, M; Brown, SK; Deng, YM; Kuba, M; Lau, H; O'Neill, G; Peck, H; Soppe, S; Subbarao, K | 1 |
Mehta, N; Peppercorn, AF; Watson, HA; Yates, PJ | 1 |
Adlhoch, C; Bossuyt, N; Brytting, M; Carnahan, A; Delgado-Sanz, C; Domegan, L; Gomes Dias, J; Guiomar, R; Kynčl, J; Larrauri, A; Maistre Melillo, J; Marbus, SD; Melillo, T; O'Donnell, J; Olsen, SJ; Popovici, O; Redlberger-Fritz, M; Slezak, P; Thomas, I; van Gageldonk-Lafeber, AB | 1 |
Chan, KKP; Hui, DSC | 1 |
Aoki, S; Chon, I; Kakuya, F; Kawashima, T; Kitano, A; Kodo, N; Li, J; Minato, M; Nagata, N; Ono, Y; Phyu, WW; Saito, R; Saito, T; Sato, I; Shimada, Y; Sun, Y; Suzuki, E; Tanaka, T; Wagatsuma, K; Watanabe, H | 1 |
Kumar, R; Sagar, R; Tyagi, R; Yadav, Y | 1 |
Angioletti-Uberti, S; Baumgardt, M; Bhatia, S; Haag, R; Herrmann, A; Hocke, AC; Hönzke, K; Khatri, V; Ludwig, K; Nie, C; Parshad, B; Rimondi, A; Schlecht, MN; Schneider, P; Wolff, T | 1 |
Bart Tarbet, E; Bejster, I; Brown, AN; Chadderdon, A; Donnelly, RF; Drusano, GL; Harteg, C; Hidayat Bin Sabri, A; Kurnia Anjani, Q; Lipka, E; Reyna, D; Vora, LK; Westover, J | 1 |
Cuanalo-Contreras, K; Islas, AA; Martinez-Laguna, Y; Scior, T | 1 |
Balligand, T; Carpenet, C; Liu, X; Ploegh, HL | 1 |
Govorkova, EA; Ivachtchenko, AV; Ivanenkov, YA; Ivashchenko, AA; Jones, JC; Karapetian, RN; Pascua, PNQ; Penaflor, MK; Shkil, DO | 1 |
Barr, IG; Bobbitt, ME; Brown, SK; Chanthalavanh, P; Dapat, C; Deng, YM; Diefenbach-Elstob, TR; Peck, H; Rynehart, C; Spirason, N; Subbarao, K | 1 |
Barreca, GS; Bruni, A; Garofalo, E; Giancotti, A; Liberto, MC; Longhini, F; Matera, G; Mazzitelli, M; Navalesi, P; Quirino, A; Serapide, F; Torti, C; Trecarichi, EM | 1 |
Barth, A; Collins, J; Hossain, M; Okour, M; Peppercorn, A; Roberts, G; Shortino, D; Watson, HA; Yates, P; Zuo, P | 1 |
Abed, Y; Boivin, G; Carbonneau, J; Checkmahomed, L; Fage, C; Giannotti, F; Goncalves, AR; Kaiser, L; Schibler, M; Venable, MC | 1 |
Martin-Loeches, I; O'Sullivan, S; Rodriguez, A; Torres, A | 1 |
Han, N; Kim, IW; Oh, JM | 1 |
Miyazaki, C; Momoi, MY; Ohkusa, Y; Okabe, N; Sugawara, T; Taniguchi, K | 1 |
Best, T; Breuer, J; Illingworth, CJR; Lumby, CK; Oporto, M; Shah, D; Tutill, H; Veys, P; Williams, R; Worth, A; Zhao, L | 1 |
Gubareva, L; Mohan, T | 1 |
Barr, IG; Brown, SK; Chow, MK; Patel, M; Peck, H; Price, OH; Rynehart, C; Soppe, S; Spirason, N; Todd, A | 1 |
Cao, R; Dai, Q; Guo, X; Li, W; Li, X; Li, Y; Xia, Q; Xu, K; Yan, Y; Yang, J; Yang, K; Zhao, L; Zhong, W; Zou, G | 1 |
Adams, SE; Bovin, NV; Donnelly, RP; Ilyushina, NA; Kan, A; Lugovtsev, VY | 1 |
Bhatia, S; Cheng, C; Haag, R; Kerkhoff, Y; Nie, C; Oehrl, A; Parshad, B; Stadtmüller, M; Wolff, T | 1 |
Akimoto, M; Fujisaki, S; Hasegawa, H; Kaido, T; Kishida, N; Kuwahara, T; Miura, H; Morita, H; Nagata, S; Nakamura, K; Sato, A; Shirakura, M; Sugawara, H; Takashita, E; Watanabe, S; Yasui, Y | 1 |
Bulgakova, VA; Gorodin, VN; Kareva, EN; Pshenichnaya, NY; Selkova, EP; Volchkova, EV | 1 |
Chung, YS; Kang, C; Kim, HM; Kim, MS; Lee, N | 1 |
Atkins, E; Bao, P; Barclay, WS; Bentham, M; Claridge, JK; Cook, GP; Elderfield, R; Evans, S; Foster, R; Foster, TL; Goldhill, DH; Griffin, S; Kankanala, J; Loundras, E; McKimmie, CS; Pingen, M; Schnell, JR; Scott, C; Simmons, K; Stilwell, PR; Targett-Adams, P; Tathineni, R; Thompson, J | 1 |
Bo, H; Dong, J; Huang, WJ; Li, XY; Liu, J; Tang, J; Wang, DY; Xin, L; Yang, L; Zhang, J; Zhang, SX; Zhou, JF; Zou, SM | 1 |
Slain, D | 1 |
Chen, Y; Chi, YM; Du, JF; Du, WX; Han, GC; Li, M; Liu, F | 1 |
Aaron, JG; DiMango, EA; Laplante, JM; Macesic, N; Miko, BA; Pereira, MR; Reshef, R; St George, K | 1 |
Jansson, M; Rello, J; Solé-Lleonart, C; Tejada, S | 1 |
Botelho-Nevers, E; Cantais, A; Cizeron, A; Gagneux-Brunon, A; Pillet, S; Saunier, F | 1 |
Laghdir, Z; Quach, C; Tadount, F | 1 |
Lee, YG; Liu, X; Low, PS; Luo, W; Shahriar, I; Srinivasarao, M; Zhang, B | 1 |
Chiba, T; Chikada, S; Matsuoka, Y; Nakano, T; Shiosakai, K; Yamaguchi, H | 1 |
Govorkova, EA; Gubareva, LV; Hay, AJ; Hayden, FG; Ison, MG; McKimm-Breschkin, JL; Takashita, E | 1 |
Chiu, HY; Lee, JA; Lin, SH; Liu, JW; Wang, LC | 1 |
Blanchon, T; Charlois-Ou, C; Chevret, S; Duval, X; Flicoteaux, R; Leport, C; Lina, B; Mosnier, A; Protopopescu, C; Tibi, A; Werf, SV | 1 |
Ikematsu, H; Iwaki, N; Kashiwagi, S; Kawai, N | 8 |
Asai, N; Furui, T; Hagihara, M; Kato, H; Kato, Y; Koizumi, Y; Kurumiya, A; Mikamo, H; Nishiyama, N; Sakata, M; Takahashi, T; Yamagishi, Y | 1 |
Besselaar, TG; Daniels, RS; Fry, A; Gregory, V; Gubareva, LV; Huang, W; Hurt, AC; Jorquera, PA; Lackenby, A; Leang, SK; Lo, J; Meijer, A; Odagiri, T; Pereyaslov, D; Rebelo-de-Andrade, H; Siqueira, MM; Takashita, E; Wang, D; Zhang, W | 1 |
Fujii, T; Higashiguchi, M; Matsumoto, T | 1 |
Buettner, I; Chow, MK; Lau, H; Leang, SK; Leung, VK; Spirason, N | 1 |
Baranovich, T; Davis, CT; Gubareva, LV; Guo, Z; Hodges, E; Sleeman, K; Stevens, J; Yang, H | 1 |
Boikos, C; Doll, MK; Gore, G; Kraicer-Melamed, H; Quach, C; Winters, N | 1 |
Ahn, SJ; Baek, YH; Chae, HB; Choi, WS; Choi, YK; Govorkova, EA; Hwang, J; Jeong, JH; Kim, CJ; Kim, MH; Kwon, HI; Kwon, JJ; Lloren, KKS; Song, MS; Webby, RJ | 1 |
Adams, B; Blumer, JL; Bradley, JS; DeBiasi, RL; Hossain, M; Kimberlin, DW; Michaels, MG; Munoz, FM; Pahud, B; Peppercorn, A; Roberts, G; Romero, JR; Shortino, D; Yamamoto, G; Yates, PJ | 1 |
Ishii, H; Ishimoto, H; Kadota, JI; Mukae, H; Nishida, C; Noguchi, S; Sakamoto, N; Umeki, K; Yamasaki, K; Yatera, K | 1 |
Behzadian, F; Kananizadeh, P; Moeini, S; Mozhgani, SH; Pakzad, R; Zarei Ghobadi, M | 1 |
Hasegawa, T; Hirotsu, N; Saisho, Y; Shishido, T | 1 |
Uyeki, TM | 2 |
Christiansen, CB; Fischer, TK; Trebbien, R | 1 |
Bailly, B; Borbás, A; Dirr, L; Dyason, JC; Gao, GF; Hadházi, Á; Li, L; Maggioni, A; Martin, G; Pascolutti, M; Thomson, RJ; Ve, T; von Itzstein, M | 1 |
Akutsu, Y; Aoyagi, H; Ariga, T; Arioka, H; Azuma, K; Furuyama, H; Hatae, Y; Hazama, K; Inagawa, A; Ishiguro, N; Ishizaka, A; Kaiho, M; Kawamura, N; Kikuta, H; Koike, A; Konno, M; Koseki, N; Kumita, Y; Matsuzono, Y; Morita, K; Murashita, M; Nagano, N; Oba, K; Odagawa, Y; Okamura, A; Sawada, Y; Shibata, M; Shida, S; Tabata, Y; Takada, K; Tobise, C; Togashi, T; Tsubakihara, K; Tsuchida, A; Tsuchiyama, A; Uetsuji, K; Watanabe, T; Yamanaka, T; Yamazaki, S; Yasoshima, K; Yasuda, K; Yoshioka, M | 1 |
Fushimi, K; Matsui, H; Michihata, N; Miyairi, I; Morisaki, N; Okubo, Y; Shoji, K; Uda, K; Yasunaga, H | 1 |
Bradbury, N; Lim, WS; Nguyen-Van-Tam, J | 1 |
Chan, KH; Hung, IFN; Kao, RYT; Lee, ACY; Li, C; To, KKW; Yuen, KY; Zhang, AJX; Zhang, RR; Zhu, H | 1 |
Ikematsu, H; Ishikawa, Y; Iwaki, N; Kashiwagi, S; Kawai, N; Shiosakai, K; Yamaguchi, H | 1 |
Bakulina, AY; Durymanov, AG; Goncharova, NI; Ilyicheva, TN; Kolosova, NP; Maksyutov, RA; Marchenko, VY; Pyankova, OG; Ryzhikov, AB; Sobolev, IA; Susloparov, IM; Svyatchenko, SV | 1 |
Albati, F; Chilundo, J; Daniels, R; Gudo, E; Machalele, L; Mateonane, E; Mavale, S; McCauley, J; Mussá, T; Muteto, D; Nacoto, A; Nguenha, N; Pale, M; Salência, J; Tivane, A | 1 |
Cocoros, NM; Haug, N; Maher, C; Panucci, G; Reichman, M; Toh, S | 1 |
Chand, M; Cleary, PR; Crofts, J; Parry-Ford, F; Phin, N | 1 |
Escuret, V; Gaymard, A; Javouhey, E; Josset, L; Lina, B; Malcus, C; Massenavette, B; Millat, G; Monneret, G; Morfin-Sherpa, F; Picard, C; Pichon, M; Renard, C; Simon, B; Valette, M | 1 |
Beard, KR; Brendish, NJ; Clark, TW | 1 |
Ben-Hamouda, N; Jahns, FP; Kirsch, M; Liaudet, L; Roumy, A | 1 |
Asai, K; Fujioka, M; Hirata, K; Kimura, T; Kureya, Y; Shinataku, H; Tocino, Y; Yoshi, N | 1 |
Block, S; Herrmann, A; Lauster, D; Müller, M; Wildenauer, HHK | 1 |
Miyazaki, C; Momoi, M; Ohkusa, Y; Okabe, N; Sugawara, T; Taniguchi, K | 1 |
Calistri, A; Del Vecchio, C; Franchin, E; Marini, G; Nicolè, S; Palù, G; Parolin, C; Salata, C; Sgarabotto, D; Solimbergo, E | 1 |
Arinaga-Hino, T; Hirai, S; Ide, T; Kawaguchi, T; Nagamatsu, H; Shimizu, M; Takata, A; Tanikawa, K; Tateishi, H; Tokushige, T; Torimura, T | 1 |
Bassetti, M; Carnelutti, A; Castaldo, N | 1 |
Betsuyaku, T; Ogawa, T; Ohgino, K; Omori, N; Sayama, K; Tanaka, K | 1 |
Buettner, I; Chow, MK; Iannello, P; Kaye, M; Lau, H; Leung, VK; Roe, M; Tolosa, MX; Zakis, T | 1 |
Cheng, Y; Huang, W; Li, X; Tang, J; Wang, D; Wei, H; Xin, L; Yang, L; Zhang, J; Zhou, J; Zhu, W; Zou, S | 1 |
Abed, Y; Boivin, G; Pizzorno, A; Samson, M | 1 |
Cabral, E; Carratalá, J; Cordero, E; Cruzado, JM; Delgado, JF; Gavaldá, J; Gómez-Bravo, MÁ; López-Medrano, F; Marcos, MÁ; Pérez-Romero, P; Sabé, N | 2 |
Fujisaki, S; Imai, M; Kishida, N; Odagiri, T; Sato, H; Takashita, E; Taniwaki, T; Tashiro, M; Xu, H; Yokoyama, M | 1 |
Coenen, S; Michiels, B; Van Puyenbroeck, K; Verhoeven, V; Vermeire, E | 1 |
Ishizuka, H; Kubo, Y; Yoshihara, K | 1 |
Gubareva, LV; Klimov, AI; Li, Y; Lysén, C; Nguyen, HT; Okomo-Adhiambo, M; Sleeman, K; Xu, X | 1 |
Kubo, T; Minakami, H; Nakai, A; Saito, S; Unno, N; Yoshimura, Y | 1 |
Jones, LS; Lou, Y; Ng-Cashin, J; Peppercorn, A; Weller, S | 1 |
Devalapally, H; Holmes, EH; Li, L; Ostrander, GK; Perdue, ML | 1 |
Booy, R; Dixit, R; Ilgoutz, S; Khandaker, G; Rashid, H | 1 |
Jones, LS; Lou, Y; Ng-Cashin, J; Peppercorn, A; Piscitelli, S; Weller, S | 1 |
Awamura, S; Ikematsu, H; Ishida, K; Kashiwagi, S; Okamoto, T; Uemori, M; Watanabe, A | 1 |
Ihashi, M; Inoue, Y; Kaneno, H; Kase, T; Mizoguchi, Y; Okabe, N; Shimotsuji, T; Yamamoto, K; Yamamoto, T | 1 |
Baranovich, T; Dapat, C; Dapat, IC; Kondo, H; Saito, K; Saito, R; Shobugawa, Y; Suzuki, H; Suzuki, Y | 1 |
Cheung, PP; Choy, KT; Guan, Y; McKimm-Breschkin, JL; Ng, IH; Peiris, JS; Webby, RJ; Webster, RG; Wong, DD; Yen, HL; Zhou, J; Zhu, H | 1 |
Gubareva, LV; Guo, L; Marjuki, H; Mishin, VP; Okomo-Adhiambo, M; Sheu, TG; Sleeman, K; Xu, X | 1 |
Hargraves, J; Patel, DM; Pitts, SR | 1 |
Ariga, T; Ishiguro, N; Kaiho, M; Kikuta, H; Koseki, N; Oba, K; Togashi, T | 1 |
Kakuta, M; Kubo, S; Tanaka, M; Tobiume, S; Tomozawa, T; Yamashita, M | 1 |
Alvarez-Lerma, F; Brealey, D; Francois, B; Garot, D; Lorente, JA; Man, CY; Mánez, R; Marty, FM; Peppercorn, AF; Thamlikitkul, V; van der Horst, C; Weller, S; Yates, PJ; Zhao, HH | 1 |
Baranovich, T; Burnham, AJ; Govorkova, EA | 1 |
Akl, EA; Alonso-Coello, P; Brozek, J; Chen, YL; Cheung, A; Flottorp, SA; Hopkins, JP; Hovhannisyan, G; Hsu, J; Ivanova, L; Mustafa, R; Saeterdal, I; Santesso, N; Schünemann, HJ; Smaill, F; Tian, J; Uyeki, TM; Wong, AD | 2 |
Hubbard, RJ; Li, J; Meyer, AE; Miller, PE; Mounts, AW; Penn, CR; Rambachan, A; Rolfes, MA; Stephens, P | 2 |
Farrukee, R; Hurt, AC; Mosse, J | 1 |
Cao, B; Hayden, FG | 1 |
Kobayashi, N; Makau, JN; Watanabe, K | 1 |
Louie, JK; Samuel, MC; Schechter, R; Uyeki, TM; Yang, S | 1 |
Chong, M; Henry, B; Kendall, P; Marra, F; Patrick, DM | 1 |
Long, B; Malaisree, M; McIntosh-Smith, S; Mulholland, AJ; Woods, CJ | 1 |
Hashimoto, K; Honzumi, K; Hosoya, M; Kawasaki, Y; Miyazaki, K; Sato, M; Sato, T; Watanabe, M | 2 |
Kmietowicz, Z | 2 |
Herxheimer, A; McGettigan, P; Pollock, A | 1 |
Dunstan, HJ; Mill, AC; Stephens, S; Thomas, SH; Yates, LM | 1 |
Chan, JF; To, KK; Yuen, KY | 1 |
Kidd, M | 1 |
Chan, JF; Chan, KH; Cheng, VC; Ho, PL; Sin, WC | 1 |
Kanda, T; Mizuno, S; Mizuno, T | 1 |
Del Mar, CB; Doshi, P; Hama, R; Heneghan, CJ; Howick, J; Jefferson, T; Jones, MA; Mahtani, KR; Nunan, D; Onakpoya, I; Spencer, EA; Thompson, MJ | 2 |
Torjesen, I | 1 |
Doshi, P; Jefferson, T | 2 |
Barr, IG; Hurt, AC; Kelso, A; Kwok, S; Leang, SK; Maurer-Stroh, S; Sullivan, SG | 1 |
Butler, D | 2 |
Godlee, F | 1 |
Nguyen-Van-Tam, JS | 2 |
Leonardi-Bee, J; Myles, PR | 2 |
Jones, M | 1 |
Belluz, J | 1 |
Heneghan, CJ; Jefferson, T; Jones, M; Onakpoya, I; Spencer, EA; Thompson, M | 1 |
Krumholz, HM | 1 |
Fry, AM | 1 |
Al Khuwaitir, TS; Al Mamun, A; Amine, IL; Anovadiya, AP; Azziz-Baumgartner, E; Báez, C; Bassetti, M; Beovic, B; Bertisch, B; Bonmarin, I; Booy, R; Borja-Aburto, VH; Burgmann, H; Cao, B; Carratala, J; Denholm, JT; Dominguez, SR; Duarte, PA; Dubnov-Raz, G; Echavarria, M; Fanella, S; Gao, Z; Gérardin, P; Giannella, M; Gubbels, S; Herberg, J; Hoger, PH; Hu, X; Iglesias, AL; Islam, QT; Jiménez, MF; Kandeel, A; Keijzers, G; Khalili, H; Knight, M; Kudo, K; Kusznierz, G; Kuzman, I; Kwan, AM; Langenegger, E; Lankarani, KB; Leo, YS; Leonardi-Bee, J; Linko, R; Liu, P; Madanat, F; Mayo-Montero, E; McGeer, A; Memish, Z; Metan, G; Mickiene, A; Mikić, D; Mohn, KG; Moradi, A; Muthuri, SG; Myles, PR; Nguyen-Van-Tam, JS; Nymadawa, P; Oliva, ME; Ozkan, M; Parekh, D; Paul, M; Polack, FP; Rath, BA; Rodríguez, AH; Sarrouf, EB; Seale, AC; Sertogullarindan, B; Siqueira, MM; Skręt-Magierło, J; Stephan, F; Talarek, E; Tang, JW; To, KK; Torres, A; Törün, SH; Tran, D; Uyeki, TM; Van Zwol, A; Vaudry, W; Venkatesan, S; Vidmar, T; Yokota, RT; Zarogoulidis, P | 1 |
Asai, T; Ichikawa, M; Ikezoe, I; Matsumoto, J; Miyagawa, S; Takemoto, Y; Yano, T | 1 |
Bamba, M; Ichikawa, M; Ide, Y; Kawakami, C; Kawaoka, Y; Mitamura, K; Sakai-Tagawa, Y; Sugaya, N; Yamaguchi, Y; Yamazaki, M; Yasuhara, R | 1 |
Nguyen-Van-Tam, JS; Nicholson, KG; Openshaw, PJ | 1 |
Moynihan, R | 1 |
Ak, Ö; Alan, S; Aslan, T; Badur, S; Balkan, II; Benzonana, N; Ceylan, B; Ciblak, M; Dokucu, AI; Engin, D; Eraksoy, H; Ergönül, Ö; Fincancı, M; Gencer, S; Göktaş, P; Gulhan, E; Gündüz, A; Inan, A; Kantürk, A; Midilli, K; Nazlıcan, O; Öncül, O; Özer, S; Özgüneş, N; Ozyurt, M; Saltoğlu, N; Sargın, F; Şimşek, F; Uzun, N; Yazıcı, S; Yıldırmak, T | 1 |
Adams, O; Gkioule, C; Grund, S; Kobbe, G; Pfeifer, N; Termos, T; Verheyen, J | 1 |
Cheng, CK; Fang, JM; Shie, JJ; Tsai, CH | 1 |
Antes, G; Meerpohl, JJ | 1 |
Del Mar, C; Hama, R; Jones, M | 1 |
Leonardi-Bee, J; Muthuri, SG; Myles, PR; Nguyen-Van-Tam, JS; Venkatesan, S | 1 |
Schumacher, M; Wolkewitz, M | 1 |
Ebell, MH | 2 |
Cueno, ME; Imai, K; Kamio, N; Ochiai, K; Saito, Y; Shimizu, K; Tamura, M | 1 |
Dhawane, A; Dinh, H; He, Y; Iyer, SS; Sweeney, J; Yang, Y; Zhang, X | 1 |
Calderon, A; Cañizares, A; Casas, I; Cuesta, I; Gonzalez, M; Gonzalez-Velasco, C; Lackenby, A; Lopez-Miragaya, I; Molinero, M; Monzon, S; Perez-Sautu, U; Pozo, F; Rey, S; Rodriguez, G | 1 |
Almeida-Santos, MM; Correia, V; Gíria, M; Rebelo-de-Andrade, H; Santos, LA | 1 |
Besselaar, T; Correia, V; Daniels, RS; Drager-Dayal, R; Fry, A; Gregory, V; Gubareva, L; Hurt, AC; Kageyama, T; Lackenby, A; Lo, J; Meijer, A; Odagiri, T; Pereyaslov, D; Rebelo-de-Andrade, H; Siqueira, MM; Takashita, E; Tashiro, M; Wang, D; Wong, S; Zhang, W | 1 |
Toniolo Neto, J | 1 |
Kubo, T; Minakami, H; Nakai, A; Saito, S; Unno, N | 1 |
Chi, HC; Hsiao, NW; Lin, CY; Shih, KC; Tang, CY; Zhou, J | 1 |
Król, E; Rychłowska, M; Szewczyk, B | 1 |
Brydak, LB; Nitsch-Osuch, A | 2 |
Michiels, B | 1 |
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Blanchon, T; Bouscambert-Duchamp, M; Boutitie, F; Cornu, C; Duval, X; Enouf, V; Escuret, V; Gaillard, S; Gueyffier, F; Leport, C; Lina, B; Mosnier, A; Van Der Werf, S | 1 |
Blanchon, T; Carrat, F; Duval, X; Flahault, A; Leport, C; Mentré, F; Mosnier, A; Tibi, A; Tubach, F; Van der Werf, S | 1 |
Cao, B; Chen, BY; Dong, JP; Gao, Y; Hu, K; Li, XL; Pu, ZH; Shu, YL; Song, SF; Wang, C; Wang, DY; Wang, J; Wei, LQ; Xu, Q; Yu, XM; Yu, YS | 1 |
Kamei, T; Mazda, O; Murata, K; Suzuki, N; Takahashi, I; Toriumi, Y | 1 |
Barbas, CF; Carrillo, N; Crowe, JE; Hayakawa, M; Thornburg, NJ; Toda, N | 1 |
Boivin, G; DePasse, JV; Fitch, A; Ghedin, E; Hamelin, ME; Holmes, EC; Papenburg, J; Pinilla, LT | 1 |
Adams, O; Borkhardt, A; Ghosh, S; Meisel, R; Schuster, FR | 1 |
Bhatt, B; Smee, DF; Tarbet, EB; von Itzstein, M | 1 |
Boucher, CA; Collins, PJ; Gamblin, SJ; Haire, LF; Hay, AJ; Liu, J; Martin, SR; Osterhaus, AD; Schutten, M; Skehel, JJ; Vachieri, SG; van der Vries, E; Walker, PA; Xiong, X | 1 |
Gillissen, A | 1 |
Hurt, AC; Kelso, A | 1 |
Kashiwagi, S; Mitsui, N; Shiosakai, K; Shiozawa, T; Tanigawa, M; Yamaguchi, F; Yamaguchi, H; Yamanouchi, N; Yoshida, S | 1 |
Fraaij, PL; Osterhaus, AD; van der Vries, E | 1 |
Birnkrant, DB; Chan-Tack, KM; Gao, A; Himaya, AC; Singer, ME; Thompson, EG; Uyeki, TM | 1 |
Azuma, T; Nakada, N; Tanaka, H; Yamashita, N | 1 |
Anekthananon, T; Charunwatthana, P; Day, N; Fukuda, C; Jittamala, P; Lawpoolsri, S; Lindegardh, N; Pukritayakamee, S; Pukrittayakamee, S; Puthavathana, P; Ratanasuwan, W; Sapchookul, P; Stepniewska, K; Suwanagool, S; Tarning, J; Taylor, WR; Werarak, P; White, NJ | 1 |
Chen, J; Haldar, J; Klibanov, AM; Lee, CM; Wang, L; Weight, AK | 1 |
Cheng, Y; Gubareva, LV; Huang, W; Klimov, AI; Levine, M; Li, X; Nguyen, HT; Shu, Y; Sleeman, K; Tan, M; Wang, D; Xing, X; Xu, X | 1 |
Cantu, J; Tita, AT | 1 |
Horton, J; Mehta, N; Tisdale, M; Yates, PJ | 1 |
Abed, Y; Boivin, G; Bouhy, X; Pizzorno, A; Rhéaume, C | 1 |
Cordonnier, C; de la Camara, R; Engelhard, D; Ljungman, P; Mohty, B | 1 |
Eda, H; Fukushima, M; Nakano, T; Niwa, S; Okumura, A; Tanabe, T; Tsutsumi, H; Yonemochi, R | 1 |
Prober, CG | 1 |
Englund, JA | 1 |
Leong, MA; Simmen, KA; Wagaman, PC | 1 |
Fleming, DM | 4 |
Clements, DA; Hamilton, JD; Huber, J; Lee, PY; Matchar, DB; Peterson, ED | 1 |
Davidson, HE; Gravenstein, S | 1 |
Bower, DJ; Slawson, JG | 1 |
Sugaya, N | 6 |
Uyeki, T; Winquist, A | 1 |
Asano, T; Fukunaga, Y; Hayakawa, J; Maeda, M; Migita, M; Ueda, T | 1 |
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Bonham, J; Conly, J; Gardam, M; Hawkins, K; Hirji, Z; Law, L; Mak, M; Mazzulli, T; O'Grady, S; Takata-Shewchuk, J | 2 |
Blanckenberg, SJ; Cooper, C; Fleming, DM; Kerr, C; Monto, AS; Pichichero, ME; Ruuskanen, O | 1 |
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Schmidt, RE | 1 |
Ajene, AN; Alfredson, TD; Cole, JA; Cook, SE; Loughlin, JE; Rosenberg, DM; Walker, AM | 1 |
Ajene, AN; Cole, JA; Cook, SE; Loughlin, JE; Rosenberg, DM; Walker, AM | 1 |
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Wutzler, P | 1 |
Carrat, F; Housset, B; Schwarzinger, M | 1 |
Da Silva, PR; Hayward, AC; Nguyen, VT | 1 |
Kudoh, S; Matsumoto, K; Sugaya, N; Suzuki, H | 2 |
Lange, W; Vogel, GE | 1 |
Bazin, H; Cavallo, JD; Hernandez, E; Lhonneux, A; Noury, J; Ramisse, F | 1 |
Dempsey, M; Jormanainen, V; Kerr, C; Lehti, H; Puhakka, T; Pulkkinen, M; Ring, CJ; Sharp, S; Tisdale, M; Vainionpää, R; Ward, C | 1 |
Balasingam, S; Bossuyt, S; Lambkin, R; Mann, A; Novelli, P; Oxford, JS | 1 |
Mitamura, K | 2 |
Calfee, DP; Hayden, FG; Hussey, EK; Lobo, M; Peng, AW | 1 |
Abrams, KR; Cooper, NJ; Nicholson, KG; Sutton, AJ; Turner, D; Wailoo, A | 1 |
Hansen, L | 3 |
Imuta, F; Toyoda, M; Toyoda, T | 1 |
Kirkbride, HA; Watson, J | 1 |
Drinka, PJ; Krause, P; Nest, L | 1 |
Harnden, A; Matheson, NJ; Sheikh, A; Shepperd, S; Symmonds-Abrahams, M | 1 |
Elliott, M; Gnann, JW; Hayden, FG; Ison, MG; Nagy-Agren, S; Paya, C; Steigbigel, R; Treannor, J; Weiss, HL | 1 |
Bellantonio, S; Rose, DN; Rothberg, MB | 1 |
Myers, JW | 1 |
Phillips, TG | 1 |
Ikematsu, H | 1 |
Kashiwagi, S | 3 |
Kaji, M | 2 |
Liedholm, H | 1 |
Pegram, PS; Williamson, JC | 2 |
Cheer, SM; Wagstaff, AJ | 2 |
Beyer, WE; de Jong, JC; Fouchier, RA; Osterhaus, AD; Rimmelzwaan, GF | 1 |
Lu, Q | 1 |
Bauer, TT; Rohde, G; Schultze-Werninghaus, G | 1 |
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Eichelberger, MC; Ottolini, MG; Prince, GA | 1 |
Szucs, TD | 1 |
Barr, IG; Hampson, AW; Hurt, AC; Komadina, N | 1 |
Klimov, A; Mungall, BA; Xu, X | 1 |
Di Natale, R; Guy, RJ; Hampson, AW; Kelly, HA; Lambert, SB; Robinson, PM; Tallis, G; Tobin, S | 1 |
Kossow, KD; Lode, H; Ruf, BR; Scholz, H; Vogel, GE; Wutzler, P | 1 |
Barr, IG; Durrant, CJ; Hampson, AW; Hurt, AC; Shaw, RP; Sjogren, HM | 1 |
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Faughnan, ME; Langley, JM | 1 |
Suzuki, H | 1 |
McKimm-Breschkin, JL | 2 |
Bergemann, R; Gyldmark, M; Hayden, FG; Morris, J; Mueller, E; Sander, B | 1 |
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Colman, PM | 2 |
Ferraris, O; Kessler, N; Lina, B | 1 |
Goto, H; Guo, CT; Hidari, KI; Kawaoka, Y; Miyamoto, D; Suzuki, T; Suzuki, Y; Takahashi, T | 1 |
Moscona, A | 2 |
Hosoya, M; Kato, K; Sato, M; Suzuki, H | 1 |
Goto, H; Horimoto, T; Kawaoka, Y; Kiso, M; Le, QM; Muramoto, Y; Nguyen, KH; Nguyen, TH; Ngyen, HH; Pham, ND; Sakai, YT; Someya, K; Suzuki, T; Suzuki, Y; Takada, A; Yamada, S | 1 |
Groeneveld, K; van der Noordaa, J | 1 |
Buchholz, U | 1 |
Bradley, D | 1 |
Amyard, M; Hampson, A; Hay, A; Hayden, F; Klimov, A; Macken, C; McKimm-Breschkin, J; Monto, A; Tashiro, M; Webster, RG; Zambon, M | 1 |
Mayor, S | 1 |
Aguado, JM; Díaz-Pedrochea, C; Escalante, F; Folgueira, D; Grande, C; Lizasoain, M; López-Medrano, F; Lumbreras, C; Sanz-Gallardo, I | 1 |
Gupta, RK; Nguyen-Van-Tam, JS | 1 |
Barr, IG; Hampson, AW; Hurt, AC; Iannello, P; Jachno, K; Komadina, N; McKimm-Breschkin, JL | 1 |
Davies, T | 1 |
Suzuki, T; Suzuki, Y; Takahashi, T | 1 |
Deray, G; Izzedine, H; Janus, N; Karie, S; Launay-Vacher, V | 1 |
Aymard, M; Hampson, AW; Hay, A; Hayden, FG; Klimov, A; Macken, C; McKimm-Breschkin, JL; Monto, AS; Tashiro, M; Webster, RG; Zambon, M | 1 |
Baccam, P; Beauchemin, C; Hayden, FG; Macken, CA; Perelson, AS | 1 |
Demicheli, V; Di Pietrantonj, C; Jefferson, TO; Jones, M; Rivetti, D | 1 |
Monto, AS; Ohmit, SE | 1 |
Del Mar, C; Jones, M | 1 |
Eng, P; Lam, WK; Liam, CK; Seto, WH; Shim, YS; Tsang, KW; Wong, TK | 1 |
Barr, IG; Deed, N; Hurt, AC; Iannello, P; Komadina, N; Tomasov, C | 1 |
Nau, JY | 1 |
Halloran, ME; Hayden, FG; Longini, IM; Monto, AS; Yang, Y | 1 |
Barr, IG; Brown, L; Hurt, AC; Komadina, N; Selleck, P; Shaw, R | 1 |
Dwyer, DE; Emery, S; Harrod, ME | 1 |
Mossad, SB | 3 |
Hayden, FG; Pavia, AT | 1 |
Monto, AS; Whitley, RJ | 1 |
Harnden, AR; Matheson, NJ; Perera, R; Sheikh, A; Symmonds-Abrahams, M | 1 |
Brydak, LB; Gawryluk, D; Machała, M; Wiatr, E | 1 |
Gras-Masse, H; Willand, N | 1 |
Martini, B | 1 |
Lynch, JP; Walsh, EE | 1 |
Hirotsu, N; Ikematsu, H; Iwaki, N; Kashiwagi, S; Kawai, N; Tanaka, O; Yamanishi, Y | 1 |
Hayden, FG; Ong, AK | 1 |
Wiwanitkit, V | 1 |
Lorin, V; Manuguerra, JC; Medeiros, R; Naffakh, N; Rameix-Welti, MA; Ribaud, P; Scieux, C; Socie, G; van der Werf, S | 1 |
Carrat, F; El Sawi, A; Gaillat, J; Grandmottet, G; Schlemmer, C | 1 |
Sun, XL | 1 |
Bettis, R; Hampel, FC; Harris, J; Henderson, FW; Kudule, L; LaForce, C; Man, CY; McElhaney, JE; Tisdale, M; Webster, A; Yates, P | 1 |
Hirotsu, N; Horii, S; Ikematsu, H; Iwaki, N; Kanazawa, H; Kashiwagi, S; Kawai, N; Kawamura, K; Kawashima, T; Maeda, T; Nagai, T; Tanaka, O; Yamauchi, S | 1 |
Crusat, M; de Jong, MD | 1 |
Wesseling, G | 1 |
von Itzstein, M | 1 |
Bouscambert-Duchamp, M; Escuret, V; Ferraris, O; Frobert, E; Grog, I; Lina, B; Morfin, F; Sabatier, M; Valette, M | 1 |
Worrall, G | 1 |
Panknin, HT; Trautmann, M | 1 |
Bovin, NV; Govorkova, EA; Gray, TE; Ilyushina, NA; Webster, RG | 1 |
Cheng, YS; Fang, JM; Jeng, KS; Shie, JJ; Su, CY; Temperton, NJ; Wang, SY; Wong, CH | 1 |
Collins, PJ; Gamblin, SJ; Haire, LF; Hay, AJ; Lin, YP; Liu, J; Martin, SR; Russell, RJ; Skehel, JJ; Walker, PA | 1 |
Moyad, MA; Robinson, LE | 1 |
Bethell, RC; Coates, JA; Healy, N; Hiscox, SA; Pearson, BA; Ryan, DM; Ticehurst, J; Tilling, J; Walcott, SM; Woods, JM | 1 |
Dyason, JC; Jin, B; Kok, GB; Oliver, SW; Pegg, MS; Smythe, ML; Van Phan, T; von Itzstein, M; White, HF; Wu, WY | 1 |
Jack, DB | 1 |
Aoki, FY; Bohnen, AM; Fleming, DM; Hayden, FG; Hirst, HM; Keene, O; Nicholson, KG; Osterhaus, AD; Treanor, JJ; Wightman, K | 1 |
Couch, RB | 2 |
Wade, RC | 1 |
Hayden, FG; Hussey, EK; Montalvo, A; Treanor, JJ; Walker, JB | 1 |
Adelman, A | 1 |
Matsumoto, K | 2 |
Bailey, KW; Barnard, DL; Huffman, JH; Kim, CU; Morrison, A; Sidwell, RW; Syndergaard, T; Wong, MH | 1 |
Bethell, R; Daniel, M; Dines, GD | 1 |
Ambrozaitis, A; Drinka, P; Gravenstein, M; Gravenstein, S; Jones, HH; Krause, P; Povinelli, L; Powers, D; Schilling, M; Shult, P | 1 |
Bethell, RC; Brenner, MK; Gubareva, LV; Matrosovich, MN; Webster, RG | 1 |
Hughes, J; Ostroff, S | 1 |
Calfee, DP; Hayden, FG | 1 |
Bethell, RC; Gubareva, LV; McCullers, JA; Webster, RG | 1 |
Stephenson, J | 2 |
Read, RC | 1 |
Heinzl, S | 1 |
Bricaire, F | 1 |
Silagy, CA | 1 |
Dove, A | 1 |
Calfee, DP; Cass, LM; Hayden, FG; Lobo, M; Peng, AW | 1 |
de Groot, R; Elliott, M; Fleming, DM; Henry, D; Keene, ON; Klein, T; Makela, M; Man, CY; Monto, AS | 1 |
Crisp, A; Elliott, MJ; Herlocher, ML; Hinson, JM; Monto, AS; Robinson, DP | 1 |
Patriarca, PA | 1 |
Aoki, FY; Hayden, FG | 1 |
Alvord, WG; Calfee, DP; Cass, LM; Fritz, RS; Hayden, FG; Peng, AW; Straus, SE; Strober, W | 1 |
Miller, JL | 1 |
Elliott, M; Freund, B; Gravenstein, S; Miller, I | 1 |
Yamey, G | 2 |
Hayden, FG | 3 |
Dunn, CJ; Goa, KL | 1 |
Campion, K; Silagy, CA | 1 |
Deeks, J; Demicheli, V; Jefferson, T; Rivetti, D | 2 |
Le Moing, V | 1 |
Kelly, GD; Laver, WG | 1 |
Barza, M | 1 |
Robb-Nicholson, C | 1 |
Green, ST | 1 |
Koopmans, PP; Simonian, S; van Loon, FP; Voordouw, AC | 1 |
Goldman, MP; Long, JK; Mossad, SB | 1 |
Vallée, JP | 1 |
Arakawa, M; Kashiwagi, S; Kawakami, Y; Kudoh, S; Matsumoto, K; Nagatake, T; Nakajima, S; Nerome, K; Numazaki, Y; Ogawa, N; Shimokata, K; Shirato, K; Yamakido, M | 1 |
Hussey, EK; Moore, KH; Peng, AW | 1 |
Gubareva, LV; Hayden, FG; Kaiser, L | 1 |
Thomas, PD | 1 |
Flack, NP; Hayden, FG; Henry, D; Kaiser, L; Keene, O | 1 |
Anderson, SR | 1 |
Lemon, M; Meade, F | 1 |
Fleming, DM; Keene, ON; Mäkelä, MJ; Man, CY; Pauksens, K; Rostila, T; Webster, A | 1 |
Aoki, F; Boivin, G; Goyette, N; Hardy, I; Trottier, S; Wagner, A | 1 |
Nkoghe, D; Scheen, AJ | 1 |
Barzilai, A; Behre, U; Hammond, J; Hedrick, JA; Henderson, FW; Keene, O; Reilly, L | 1 |
Chapple, KJ; Hendrick, AE; McCarthy, MW | 1 |
Zambon, MC | 1 |
Keene, O; Monto, AS; Webster, A | 1 |
Aoki, FY; Edmundson, S; Fleming, DM; Griffin, AD; Lacey, LA | 1 |
Cates, SC; Griffin, AD; Lamb, SC; Mauskopf, JA; Neighbors, DM; Rutherford, C | 1 |
Elliot, MJ; Gubareva, LV; Hammond, JM; Hayden, FG; Klein, TC; Monto, AS; Ossi, MJ; Sharp, SJ | 1 |
Wright, P | 1 |
Vogel, G; Wutzler, P | 1 |
Elliott, M; Hammond, JM; Hayden, FG; Kaiser, L; Keene, ON | 1 |
Colopy, M; Elliott, M; Gravenstein, S; Monto, AS; Schweinle, J | 1 |
Fearon, M; Lee, C; Li, Y; Loeb, M; Mazzulli, T; McArthur, MA; McGeer, A; Nesbitt, J; Phillips, A; Smith, K | 1 |
Caserta, MT; Hall, CB | 1 |
Monto, AS; Moult, AB; Sharp, SJ | 1 |
Ashley, JV; Gum, KD; Montalto, NJ | 1 |
Conly, JM; Lim, S; Richardson, D | 1 |
Rosen, DS | 1 |
Campion, K; Keene, O; Lalezari, J; Silagy, C | 1 |
Snell, J | 1 |
Briganti, E; Calza, L; Chiodo, F; Manfredi, R | 1 |
McNicholl, IR; McNicholl, JJ | 1 |
Bernsen, RM; van Bentveld, RD; van der Wouden, JC | 1 |
Feder, HM | 1 |
Osterhaus, A; Penn, CR | 1 |
Diggory, P; Fernandez, C; Humphrey, A; Jones, V; Murphy, M | 1 |
Westergren, T | 1 |
Fleming, DM; Griffin, AD; Perry, AS | 1 |
Brocavich, J; Dreitlein, WB; Maratos, J | 1 |
Abad-Santos, F; Gallego Sandín, S; Gálvez Múgica, MA; Martínez Sancho, E; Novalbos Reina, J | 1 |
Groman, E; Hartl, HK; Kunze, U; Vymazal, K | 1 |
Hayden, FG; Zambon, M | 1 |
Cross, J; Wedekind, CA | 1 |
Hall, GH | 1 |
Tooley, P | 1 |
Garman, E; Laver, G | 1 |
Hays, J; Keene, O; Newman, R; Webster, A; Zambon, M | 1 |
Preboth, M | 1 |
Holdiness, MR | 1 |
Aoki, F; Macaulay, A; Martin, B; Orr, P; Van Caeseele, P | 1 |
Gravenstein, S; Johnston, SL; Loeschel, E; Webster, A | 1 |
Elliott, M | 1 |
Barnett, D | 1 |
Roberts, NA | 1 |
Collier, J | 1 |
Pasanen, M; Tokola, O | 1 |
Carrington, D; Clark, A; Johny, AA; Marks, DI; Oakhill, A; Price, N | 1 |
MacConnachie, AM | 1 |
Senior, K | 1 |
Farr, BM; Hall, KK; Hayden, FG; Salgado, CD | 1 |
Pitts, SR | 1 |
Bridges, CB; Cox, NJ; Fukuda, K; Singleton, JA; Uyeki, TM | 1 |
Boivin, G; Goyette, N | 1 |
Bryan, S; Burls, A; Clark, W; Fry-Smith, A; Jefferson, T; Preston, C; Stewart, T | 1 |
195 review(s) available for zanamivir and Grippe
Article | Year |
---|---|
Comparative effectiveness of neuraminidase inhibitors in patients with influenza: A systematic review and network meta-analysis.
Topics: Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Network Meta-Analysis; Neuraminidase; Oseltamivir; Zanamivir | 2022 |
Antiviral Treatments for Influenza.
Topics: Antiviral Agents; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2021 |
The current strategies of optimization of oseltamivir against mutant neuraminidases of influenza A:A review.
Topics: Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Glycoside Hydrolases; Guanidines; Humans; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Zanamivir | 2022 |
Antiviral therapies for influenza.
Topics: Antiviral Agents; COVID-19; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2023 |
Conformationally locked sugar derivatives and analogues as potential neuraminidase inhibitors.
Topics: Antiviral Agents; Cyclohexenes; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Orthomyxoviridae; Oseltamivir; Zanamivir | 2023 |
Influenza management with new therapies.
Topics: Adrenal Cortex Hormones; Amides; Antiviral Agents; Critical Care; Critical Illness; Dibenzothiepins; Enzyme Inhibitors; Humans; Influenza, Human; Morpholines; Neuraminidase; Oseltamivir; Pyrazines; Pyridines; Pyridones; Pyrimidines; Pyrroles; Respiration, Artificial; Triazines; Zanamivir | 2020 |
Antivirals Targeting the Neuraminidase.
Topics: Antibodies, Monoclonal; Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2022 |
Neuraminidase inhibitors are effective and safe in reducing influenza complications: meta-analysis of randomized controlled trials.
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Randomized Controlled Trials as Topic; Zanamivir | 2021 |
Antiviral use in healthcare workers-A systematic review.
Topics: Antiviral Agents; Enzyme Inhibitors; Health Personnel; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2022 |
Influenza polymerase inhibitor resistance: Assessment of the current state of the art - A report of the isirv Antiviral group.
Topics: Animals; Antiviral Agents; Dibenzothiepins; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza, Human; Knowledge; Morpholines; Neuraminidase; Oseltamivir; Pyridones; SARS-CoV-2; Triazines; Virus Replication; Zanamivir | 2021 |
Comparison of Antiviral Agents for Seasonal Influenza Outcomes in Healthy Adults and Children: A Systematic Review and Network Meta-analysis.
Topics: Adolescent; Adult; Antiviral Agents; Child; Dibenzothiepins; Endonucleases; Enzyme Inhibitors; Female; Humans; Influenza A virus; Influenza, Human; Male; Middle Aged; Morpholines; Network Meta-Analysis; Neuraminidase; Pyridones; Randomized Controlled Trials as Topic; Seasons; Triazines; Young Adult; Zanamivir | 2021 |
A meta-analysis of laninamivir octanoate for treatment and prophylaxis of influenza.
Topics: Administration, Inhalation; Antiviral Agents; Betainfluenzavirus; Disease Management; Drug Therapy, Combination; Guanidines; Humans; Influenza A virus; Influenza, Human; Post-Exposure Prophylaxis; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2018 |
Safety and effectiveness of neuraminidase inhibitors for influenza treatment, prophylaxis, and outbreak control: a systematic review of systematic reviews and/or meta-analyses.
Topics: Antiviral Agents; Disease Outbreaks; Enzyme Inhibitors; Hospitalization; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pneumonia; Zanamivir | 2017 |
Prevalence of human influenza virus in Iran: Evidence from a systematic review and meta-analysis.
Topics: Amantadine; Antiviral Agents; Drug Resistance, Viral; Female; Humans; Incidence; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Iran; Male; Oseltamivir; Prevalence; Zanamivir | 2018 |
Treatment of influenza with neuraminidase inhibitors.
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Viral Proteins; Zanamivir | 2018 |
Neuraminidase inhibitors as a strategy for influenza treatment: pros, cons and future perspectives.
Topics: Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Half-Life; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2019 |
Influenza virus resistance to neuraminidase inhibitors.
Topics: Animals; Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Viral Proteins; Zanamivir | 2013 |
Executive summary. Management of influenza infection in solid-organ transplant recipients: consensus statement of the Group for the Study of Infection in Transplant Recipients (GESITRA) of the Spanish Society of Infectious Diseases and Clinical Microbiolo
Topics: Adult; Anti-Bacterial Agents; Antiviral Agents; Child; Cross Infection; Disease Management; Drug Resistance, Viral; Humans; Influenza Vaccines; Influenza, Human; Organ Transplantation; Oseltamivir; Postoperative Complications; Superinfection; Zanamivir | 2013 |
Management of influenza infection in solid-organ transplant recipients: consensus statement of the Group for the Study of Infection in Transplant Recipients (GESITRA) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the
Topics: Adult; Anti-Bacterial Agents; Antiviral Agents; Child; Cross Infection; Diagnosis, Differential; Disease Management; Drug Resistance, Viral; HN Protein; Humans; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Inpatients; Kidney Diseases; Organ Transplantation; Oseltamivir; Outpatients; Pneumonia; Postoperative Complications; Superinfection; Zanamivir | 2013 |
The value of neuraminidase inhibitors for the prevention and treatment of seasonal influenza: a systematic review of systematic reviews.
Topics: Antibiotic Prophylaxis; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Treatment Outcome; Zanamivir | 2013 |
Emergence of oseltamivir resistance: control and management of influenza before, during and after the pandemic.
Topics: Adult; Antibiotic Prophylaxis; Antiviral Agents; Child; Dose-Response Relationship, Drug; Drug Resistance, Viral; Enzyme Inhibitors; Global Health; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation, Missense; Neuraminidase; Oseltamivir; Pandemics; Viral Proteins; Zanamivir | 2013 |
Neuraminidase inhibitors for influenza B virus infection: efficacy and resistance.
Topics: Acids, Carbocyclic; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Viral Proteins; Zanamivir | 2013 |
Antivirals for influenza: a summary of a systematic review and meta-analysis of observational studies.
Topics: Antiviral Agents; Drug-Related Side Effects and Adverse Reactions; Humans; Influenza, Human; Oseltamivir; Survival Analysis; Treatment Outcome; Zanamivir | 2013 |
Supply of neuraminidase inhibitors related to reduced influenza A (H1N1) mortality during the 2009-2010 H1N1 pandemic: summary of an ecological study.
Topics: Antiviral Agents; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Pandemics; Survival Analysis; Treatment Outcome; Viral Proteins; Zanamivir | 2013 |
Review of the clinical effectiveness of the neuraminidase inhibitors against influenza B viruses.
Topics: Antiviral Agents; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Microbial Sensitivity Tests; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2013 |
Antiviral drugs for influenza 2013-2014.
Topics: Animals; Antiviral Agents; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Zanamivir | 2014 |
Viral lung infections: epidemiology, virology, clinical features, and management of avian influenza A(H7N9).
Topics: Animals; Antiviral Agents; China; Commerce; Communicable Disease Control; Communicable Diseases, Emerging; Disease Outbreaks; Drug Resistance, Multiple, Viral; Enzyme Inhibitors; Food Supply; Hong Kong; Humans; Influenza A Virus, H7N9 Subtype; Influenza in Birds; Influenza, Human; Neuraminidase; Poultry; Reverse Transcriptase Polymerase Chain Reaction; Taiwan; Zanamivir; Zoonoses | 2014 |
Influenza viruses: update on epidemiology, clinical features, treatment and vaccination.
Topics: Animals; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza A Virus, H7N9 Subtype; Influenza in Birds; Influenza, Human; Male; Pandemics; Poultry; Seasons; Sentinel Surveillance; Sequence Analysis, DNA; Viral Vaccines; Zanamivir | 2014 |
Neuraminidase inhibitors for preventing and treating influenza in adults and children.
Topics: Adult; Antiviral Agents; Child; Drug Evaluation; Enzyme Inhibitors; Europe; Health Status; Humans; Influenza, Human; Japan; Legislation, Drug; Neuraminidase; Oseltamivir; Pneumonia; Publication Bias; Randomized Controlled Trials as Topic; United Kingdom; United States; Zanamivir | 2014 |
Zanamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments.
Topics: Adult; Antiviral Agents; Child; Humans; Influenza, Human; Randomized Controlled Trials as Topic; Treatment Outcome; Zanamivir | 2014 |
Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data.
Topics: Adolescent; Adult; Antiviral Agents; Child; Enzyme Inhibitors; Female; Hospitalization; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Neuraminidase; Oseltamivir; Pandemics; Proportional Hazards Models; Treatment Outcome; Young Adult; Zanamivir | 2014 |
[Multisystem failure: the story of antinfluenza drugs].
Topics: Antiviral Agents; Clinical Trials as Topic; Evidence-Based Medicine; Global Health; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Italy; Neuraminidase; Oseltamivir; Pandemics; Publication Bias; Randomized Controlled Trials as Topic; Risk Factors; Zanamivir | 2014 |
From neuraminidase inhibitors to conjugates: a step towards better anti-influenza drugs?
Topics: Animals; Antiviral Agents; Drug Design; Enzyme Inhibitors; Humans; Influenza, Human; Molecular Targeted Therapy; Neuraminidase; Orthomyxoviridae; Orthomyxoviridae Infections; Zanamivir | 2014 |
Antivirals--current trends in fighting influenza.
Topics: Amantadine; Antiviral Agents; Disease Outbreaks; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Oseltamivir; Rimantadine; Viral Matrix Proteins; Zanamivir | 2014 |
Influenza viruses resistant to neuraminidase inhibitors.
Topics: Adult; Aged; Antiviral Agents; Child; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2014 |
Developments in the treatment of severe influenza: lessons from the pandemic of 2009 and new prospects for therapy.
Topics: Animals; Antiviral Agents; Birds; Enzyme Inhibitors; Humans; Immunologic Factors; Influenza in Birds; Influenza, Human; Neuraminidase; Oseltamivir; Pandemics; Population Surveillance; Public Health; Randomized Controlled Trials as Topic; Zanamivir | 2014 |
Antiviral drugs for seasonal influenza 2014-2015.
Topics: Administration, Inhalation; Administration, Oral; Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Seasons; Zanamivir | 2014 |
Clinical experience with intravenous zanamivir under an Emergency IND program in the United States (2011-2014).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Investigational New Drug Application; Male; Middle Aged; Oseltamivir; Pregnancy; Retrospective Studies; United States; Young Adult; Zanamivir | 2015 |
Optimizing antiviral therapy for influenza: understanding the evidence.
Topics: Acids, Carbocyclic; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; RNA-Dependent RNA Polymerase; Sialic Acids; Viral Matrix Proteins; Viral Proteins; Zanamivir | 2015 |
Antiviral medications for influenza.
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Treatment Outcome; Zanamivir | 2015 |
Antiviral therapy in seasonal influenza and 2009 H1N1 pandemic influenza: Korean experiences and perspectives.
Topics: Acids, Carbocyclic; Amides; Antiviral Agents; Clinical Trials as Topic; Cyclopentanes; Drug Resistance, Viral; Guanidines; Hospitalization; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Pyrans; Pyrazines; Republic of Korea; Sialic Acids; Zanamivir | 2015 |
Treatment and prophylaxis of influenza and the problem of resistance to neuraminidase inhibitors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Drug Resistance, Viral; Enzyme Inhibitors; Female; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Neuraminidase; Oseltamivir; Young Adult; Zanamivir | 2015 |
Influenza and its treatment during pregnancy: A review.
Topics: Animals; Antiviral Agents; Female; Humans; Influenza Vaccines; Influenza, Human; Membrane Transport Proteins; Oseltamivir; Post-Exposure Prophylaxis; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Vaccination; Zanamivir | 2015 |
Neuraminidase inhibitors for influenza: a systematic review and meta-analysis of regulatory and mortality data.
Topics: Adult; Antiviral Agents; Asthma; Child; Dose-Response Relationship, Drug; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Randomized Controlled Trials as Topic; Zanamivir | 2016 |
Antiviral therapy for respiratory viral infections in immunocompromised patients.
Topics: Acids, Carbocyclic; Amantadine; Antiviral Agents; Coronavirus Infections; Cyclopentanes; Guanidines; Humans; Immunocompromised Host; Influenza, Human; Oseltamivir; Palivizumab; Paramyxoviridae Infections; Picornaviridae Infections; Respiratory Syncytial Virus Infections; Respiratory Tract Infections; Ribavirin; Zanamivir | 2017 |
Safety and effectiveness of neuraminidase inhibitors in situations of pandemic and/or novel/variant influenza: a systematic review of the literature, 2009-15.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Child; Child, Preschool; Clinical Trials as Topic; Disease Outbreaks; Enzyme Inhibitors; Female; Humans; Infant; Infant, Newborn; Influenza, Human; Male; Middle Aged; Neuraminidase; Observational Studies as Topic; Oseltamivir; Pandemics; Pneumonia; Young Adult; Zanamivir | 2017 |
Clinical Mimics: An Emergency Medicine-Focused Review of Influenza Mimics.
Topics: Acids, Carbocyclic; Aged; Aged, 80 and over; Antiviral Agents; Child, Preschool; Cyclopentanes; Emergency Medicine; Guanidines; Humans; Infant; Influenza, Human; Middle Aged; Oseltamivir; Risk Factors; United States; Zanamivir | 2017 |
[Influenza].
Topics: Adolescent; Adult; Age Factors; Aged; Amantadine; Anti-Bacterial Agents; Antiviral Agents; Child; Child, Preschool; Diagnosis, Differential; Female; Follow-Up Studies; France; Humans; Infant; Influenza Vaccines; Influenza, Human; Male; Oseltamivir; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Seasons; Time Factors; Treatment Outcome; Zanamivir | 2008 |
[Antiviral treatment of influenza in humans].
Topics: Amantadine; Animals; Antiviral Agents; Clinical Trials as Topic; Disease Outbreaks; Drug Resistance, Viral; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Oseltamivir; Rimantadine; Virus Replication; Virus Shedding; Zanamivir | 2007 |
Modifying clinical practices to manage influenza in children effectively.
Topics: Adolescent; Animals; Antiviral Agents; Chemoprevention; Child; Child, Preschool; Hospitalization; Humans; Infant; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H2N2 Subtype; Influenza A Virus, H5N1 Subtype; Influenza B virus; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2008 |
[Neuraminidase inhibitors in prophylaxis and treatment of influenza].
Topics: Antiviral Agents; Disease Outbreaks; Drug Administration Schedule; Enzyme Inhibitors; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2008 |
Anti-influenza drugs: the development of sialidase inhibitors.
Topics: Animals; Antiviral Agents; Drug Design; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Neuraminidase; Orthomyxoviridae; Zanamivir | 2009 |
Developing new antiviral agents for influenza treatment: what does the future hold?
Topics: Acids, Carbocyclic; Amides; Animals; Antiviral Agents; Cyclopentanes; Drug Discovery; Drug Resistance, Viral; Drug Therapy, Combination; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza, Human; Neuraminidase; Pyrazines; Recombinant Fusion Proteins; Zanamivir | 2009 |
Amantadine, oseltamivir and zanamivir for the prophylaxis of influenza (including a review of existing guidance no. 67): a systematic review and economic evaluation.
Topics: Amantadine; Antiviral Agents; Cost-Benefit Analysis; Humans; Influenza, Human; Models, Economic; Oseltamivir; Practice Guidelines as Topic; Premedication; Randomized Controlled Trials as Topic; Seasons; Treatment Outcome; Zanamivir | 2009 |
Emerging antiviral targets for influenza A virus.
Topics: Animals; Antiviral Agents; Drug Delivery Systems; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; RNA-Dependent RNA Polymerase; Viral Nonstructural Proteins; Zanamivir | 2009 |
Influenza.
Topics: Acute Disease; Administration, Inhalation; Humans; Incidence; Influenza Vaccines; Influenza, Human; Oseltamivir; Rimantadine; Zanamivir | 2009 |
Antivirals for the treatment and prevention of epidemic and pandemic influenza.
Topics: Amantadine; Antiviral Agents; Chemoprevention; Disease Outbreaks; Drug Resistance, Viral; Humans; Influenza, Human; Oseltamivir; Rimantadine; Zanamivir | 2007 |
Reducing the burden of influenza-associated complications with antiviral therapy.
Topics: Age Factors; Antiviral Agents; Cost of Illness; Enzyme Inhibitors; Health Care Costs; Humans; Influenza, Human; Neuraminidase; Risk Factors; Treatment Outcome; Zanamivir | 2009 |
Safety of neuraminidase inhibitors against novel influenza A (H1N1) in pregnant and breastfeeding women.
Topics: Breast Feeding; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Lactation; Neuraminidase; Oseltamivir; Pregnancy; Pregnancy Complications, Infectious; Treatment Outcome; Viral Vaccines; Zanamivir | 2009 |
Synthetic approaches to the neuraminidase inhibitors zanamivir (Relenza) and oseltamivir phosphate (Tamiflu) for the treatment of influenza.
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2009 |
Systematic review: safety and efficacy of extended-duration antiviral chemoprophylaxis against pandemic and seasonal influenza.
Topics: Antiviral Agents; Disease Outbreaks; Drug Administration Schedule; Humans; Influenza A virus; Influenza, Human; Nausea; Neuraminidase; Oseltamivir; Risk Factors; Vomiting; Zanamivir | 2009 |
Prescription of anti-influenza drugs for healthy adults: a systematic review and meta-analysis.
Topics: Adult; Antiviral Agents; Humans; Influenza, Human; Oseltamivir; Treatment Outcome; United Kingdom; Zanamivir | 2009 |
Neuraminidase inhibitors for treatment and prophylaxis of influenza in children: systematic review and meta-analysis of randomised controlled trials.
Topics: Anti-Bacterial Agents; Antiviral Agents; Asthma; Bias; Child; Child, Preschool; Enzyme Inhibitors; Humans; Infant; Influenza, Human; Neuraminidase; Oseltamivir; Otitis Media; Randomized Controlled Trials as Topic; Risk Factors; Zanamivir | 2009 |
[Pandemic influenza A H1N1 2009 flu during pregnancy: Epidemiology, diagnosis and management].
Topics: Antiviral Agents; Disease Outbreaks; Female; France; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Nasopharynx; Oseltamivir; Pregnancy; Pregnancy Complications, Infectious; Zanamivir | 2009 |
The use of antiviral agents for the management of severe influenza.
Topics: Age Factors; Antiviral Agents; Drug Therapy, Combination; Humans; Immunocompromised Host; Influenza A Virus, H1N1 Subtype; Influenza, Human; Interferons; Length of Stay; Neuraminidase; Oseltamivir; Practice Guidelines as Topic; Ribavirin; Risk Factors; Viral Load; Zanamivir | 2010 |
Antiviral treatment and prophylaxis of influenza virus in children.
Topics: Amantadine; Antiviral Agents; Chemoprevention; Child; Child, Preschool; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Post-Exposure Prophylaxis; Zanamivir | 2009 |
[Research progress of neuraminidase inhibitors for anti-influenza].
Topics: Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2009 |
Neuraminidase inhibitors for preventing and treating influenza in healthy adults.
Topics: Adult; Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Post-Exposure Prophylaxis; Randomized Controlled Trials as Topic; Zanamivir | 2010 |
[Role of neuraminidase inhibitors for the treatment of influenza A virus infections].
Topics: Adult; Antiviral Agents; Child; Clinical Trials as Topic; Disease Outbreaks; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; Humans; Immunocompromised Host; Influenza A virus; Influenza, Human; Male; Models, Molecular; Molecular Structure; Mutation, Missense; Neuraminidase; Oseltamivir; Point Mutation; Pregnancy; Pregnancy Complications, Infectious; Protein Conformation; Viral Proteins; Zanamivir | 2010 |
Targeting pandemic influenza: a primer on influenza antivirals and drug resistance.
Topics: Acids, Carbocyclic; Antiviral Agents; Cyclopentanes; Disease Outbreaks; Drug Resistance, Viral; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Models, Biological; Oseltamivir; Recombinant Fusion Proteins; Zanamivir | 2010 |
[Influenza A, pregnancy and neuraminidase inhibitors].
Topics: Animals; Antiviral Agents; Australia; Centers for Disease Control and Prevention, U.S.; Drug Evaluation, Preclinical; Drug Utilization; Europe; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Neuraminidase; New Zealand; Oseltamivir; Pandemics; Practice Guidelines as Topic; Pregnancy; Pregnancy Outcome; Risk Assessment; United States; Viral Proteins; World Health Organization; Zanamivir | 2011 |
Influenza in the tropics.
Topics: Animals; Antiviral Agents; Disease Outbreaks; Drug Resistance, Viral; Genetic Variation; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Influenza B virus; Influenza, Human; Oseltamivir; Prevalence; Tropical Climate; Zanamivir | 2010 |
Swine flu.
Topics: Antiviral Agents; Contact Tracing; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Oseltamivir; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Travel; Zanamivir | 2009 |
[Change of strategies for novel and seasonal flu during pregnancy].
Topics: Antiviral Agents; Disease Outbreaks; Female; Humans; Influenza Vaccines; Influenza, Human; Oseltamivir; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Zanamivir | 2010 |
[Present and future in development of new anti-influenza drugs].
Topics: Amantadine; Antiviral Agents; DNA-Directed RNA Polymerases; Drug Design; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2010 |
[Current anti-influenza virus chemotherapy].
Topics: Acids, Carbocyclic; Amantadine; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Drug Utilization; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Infusions, Intravenous; Japan; Oseltamivir; Pandemics; Zanamivir | 2010 |
[Influenza A/H1N1v 2009 during pregnancy and breastfeeding: which antiviral to choose?].
Topics: Adult; Antiviral Agents; Breast Feeding; Female; Fetus; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Oseltamivir; Pregnancy; Zanamivir | 2010 |
Treatment options for H5N1: lessons learned from the H1N1 pandemic.
Topics: Acids, Carbocyclic; Antiviral Agents; Cyclopentanes; Disease Outbreaks; Drug Resistance, Viral; Guanidines; Humans; Immunocompromised Host; Influenza A Virus, H5N1 Subtype; Influenza, Human; Oseltamivir; Pneumonia, Viral; Pyrans; Severity of Illness Index; Sialic Acids; Zanamivir | 2010 |
Oseltamivir, zanamivir and amantadine in the prevention of influenza: a systematic review.
Topics: Amantadine; Antiviral Agents; Disease Outbreaks; Humans; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; Post-Exposure Prophylaxis; Treatment Outcome; Viral Matrix Proteins; Zanamivir | 2011 |
Laninamivir and its prodrug, CS-8958: long-acting neuraminidase inhibitors for the treatment of influenza.
Topics: Animals; Antiviral Agents; Disease Models, Animal; Drug Administration Routes; Drug Administration Schedule; Guanidines; Humans; Influenza, Human; Mice; Neuraminidase; Orthomyxoviridae; Oseltamivir; Pandemics; Prodrugs; Pyrans; Rats; Sialic Acids; Zanamivir | 2010 |
[Research progress of anti-influenza virus agents].
Topics: Acids, Carbocyclic; Amantadine; Antiviral Agents; Cyclopentanes; Guanidines; Humans; Indoles; Influenza, Human; Neuraminidase; Orthomyxoviridae; Oseltamivir; Pyrrolidines; Rimantadine; Structure-Activity Relationship; Viral Matrix Proteins; Zanamivir | 2010 |
Influenza vaccination, diagnosis, and treatment in children.
Topics: Antiviral Agents; Child; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Oseltamivir; Real-Time Polymerase Chain Reaction; Vaccination; Zanamivir | 2011 |
Antiviral drugs for viruses other than human immunodeficiency virus.
Topics: Acyclovir; Adenine; Amantadine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Foscarnet; Ganciclovir; Guanine; Hepatitis; Hepatitis B, Chronic; Hepatitis C; Herpesviridae Infections; HIV Infections; Humans; Influenza, Human; Interferons; Lamivudine; Nucleosides; Oligopeptides; Organophosphonates; Oseltamivir; Proline; Protease Inhibitors; Pyrimidinones; Ribavirin; Telbivudine; Thymidine; Valacyclovir; Valganciclovir; Valine; Virus Replication; Zanamivir | 2011 |
Laninamivir octanoate: a new long-acting neuraminidase inhibitor for the treatment of influenza.
Topics: Administration, Inhalation; Adult; Animals; Antiviral Agents; Birds; Caprylates; Child; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Influenza B virus; Influenza in Birds; Influenza, Human; Japan; Neuraminidase; Oseltamivir; Prodrugs; Pyrans; Sialic Acids; Viral Proteins; Virus Replication; Zanamivir | 2011 |
Antiviral drugs for influenza.
Topics: Adult; Amantadine; Antiviral Agents; Child; Female; Humans; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; Pregnancy; Rimantadine; Zanamivir | 2012 |
Neuraminidase inhibitors for preventing and treating influenza in children.
Topics: Acetamides; Antiviral Agents; Child; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Zanamivir | 2012 |
Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children.
Topics: Adult; Antiviral Agents; Child; Drug Evaluation; Enzyme Inhibitors; Europe; Health Status; Humans; Influenza, Human; Japan; Legislation, Drug; Neuraminidase; Oseltamivir; Publication Bias; Randomized Controlled Trials as Topic; United Kingdom; United States; Zanamivir | 2012 |
Antivirals for treatment of influenza: a systematic review and meta-analysis of observational studies.
Topics: Administration, Inhalation; Administration, Oral; Amantadine; Antiviral Agents; Confounding Factors, Epidemiologic; Hospitalization; Humans; Influenza, Human; Oseltamivir; Rimantadine; Treatment Outcome; Zanamivir | 2012 |
Neuraminidase inhibitors for preventing and treating influenza in children (published trials only).
Topics: Antiviral Agents; Child; Child, Preschool; Enzyme Inhibitors; Guanidines; Humans; Infant; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Zanamivir | 2012 |
Recent advances in neuraminidase inhibitor development as anti-influenza drugs.
Topics: Acids, Carbocyclic; Animals; Antiviral Agents; Benzoic Acid; Cyclopentanes; Drug Design; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza, Human; Models, Molecular; Neuraminidase; Orthomyxoviridae; Orthomyxoviridae Infections; Oseltamivir; Zanamivir | 2012 |
Antiviral drugs for influenza 2012-2013.
Topics: Animals; Antiviral Agents; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2012 |
Management of influenza in pregnancy.
Topics: Antiviral Agents; Female; Humans; Influenza Vaccines; Influenza, Human; Oseltamivir; Patient Isolation; Pregnancy; Pregnancy Complications, Infectious; Zanamivir | 2013 |
European guidelines for prevention and management of influenza in hematopoietic stem cell transplantation and leukemia patients: summary of ECIL-4 (2011), on behalf of ECIL, a joint venture of EBMT, EORTC, ICHS, and ELN.
Topics: Acetamides; Antiviral Agents; Hematopoietic Stem Cell Transplantation; Humans; Influenza, Human; Leukemia; Oseltamivir; Practice Guidelines as Topic; Zanamivir | 2013 |
Antiviral therapy for influenza virus infections.
Topics: Acetamides; Age Factors; Amantadine; Antiviral Agents; Child; Clinical Trials as Topic; Global Health; Guanidines; Humans; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2002 |
Antiviral therapy of influenza.
Topics: Acetamides; Administration, Inhalation; Administration, Oral; Adult; Amantadine; Antiviral Agents; Child; Drug Resistance, Viral; Guanidines; Humans; Infant; Influenza, Human; Orthomyxoviridae; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2002 |
The management of influenza in people of working age.
Topics: Acetamides; Adolescent; Adult; Amantadine; Antiviral Agents; Cost-Benefit Analysis; Guanidines; Humans; Influenza, Human; Middle Aged; Occupational Health; Oseltamivir; Pyrans; Sialic Acids; United Kingdom; Workplace; Zanamivir | 2002 |
[A revolutionary change in the diagnosis and treatment of influenza].
Topics: Acetamides; Antiviral Agents; Encephalitis, Viral; Enzyme Inhibitors; Guanidines; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Immunologic Tests; Influenza Vaccines; Influenza, Human; Neuraminidase; Orthomyxoviridae; Oseltamivir; Pyrans; Sialic Acids; Vaccines, Attenuated; Zanamivir | 2002 |
Influenza.
Topics: Acetamides; Administration, Inhalation; Administration, Oral; Adult; Amantadine; Antiviral Agents; Child; Guanidines; Humans; Influenza, Human; Oseltamivir; Pyrans; Randomized Controlled Trials as Topic; Rimantadine; Sialic Acids; Treatment Outcome; Zanamivir | 2002 |
Antivirals for influenza: what is their role in the older patient?
Topics: Acetamides; Aged; Amantadine; Antiviral Agents; Drug Resistance, Viral; Guanidines; Humans; Influenza, Human; Oseltamivir; Practice Guidelines as Topic; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2002 |
Efficacy and safety of zanamivir in patients with influenza--impact of age, severity of infections and specific risk factors.
Topics: Administration, Oral; Age Factors; Antiviral Agents; Bacterial Infections; Chronic Disease; Double-Blind Method; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Lung Diseases; Pyrans; Risk Factors; Sialic Acids; Time Factors; Treatment Outcome; Zanamivir | 2002 |
Neuraminidase inhibitors in pediatric patients: potential place in influenza therapy.
Topics: Acetamides; Child; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Otitis Media; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Zanamivir | 2003 |
Influenza diagnosis and treatment in children: a review of studies on clinically useful tests and antiviral treatment for influenza.
Topics: Acetamides; Adolescent; Age Distribution; Amantadine; Antiviral Agents; Centers for Disease Control and Prevention, U.S.; Child; Child, Preschool; DNA, Viral; Female; Fluorescent Antibody Technique, Direct; Follow-Up Studies; Guanidines; Humans; Incidence; Infant; Influenza, Human; Male; Orthomyxoviridae; Oseltamivir; Pyrans; Risk Assessment; Severity of Illness Index; Sex Distribution; Sialic Acids; Treatment Outcome; United States; Zanamivir | 2003 |
Treatment of epidemic and pandemic influenza with neuraminidase and M2 proton channel inhibitors.
Topics: Acetamides; Amantadine; Antiviral Agents; Clinical Trials as Topic; Disease Outbreaks; Endemic Diseases; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Viral Matrix Proteins; Zanamivir | 2003 |
[Influenza].
Topics: Acetamides; Amantadine; Antiviral Agents; Diagnosis, Differential; Enzyme Inhibitors; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Reagent Kits, Diagnostic; Sialic Acids; Vaccines, Attenuated; Zanamivir | 2003 |
[Antiviral agents for influenza].
Topics: Acetamides; Age Factors; Amantadine; Antiviral Agents; Drug Resistance, Viral; Guanidines; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Viral Matrix Proteins; Zanamivir | 2003 |
Zanamivir in the treatment of influenza.
Topics: Adult; Animals; Antiviral Agents; Child; Clinical Trials as Topic; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Pyrans; Risk Factors; Sialic Acids; Zanamivir | 2003 |
Effectiveness of neuraminidase inhibitors in treatment and prevention of influenza A and B: systematic review and meta-analyses of randomised controlled trials.
Topics: Acetamides; Adolescent; Adult; Aged; Antiviral Agents; Child; Child, Preschool; Enzyme Inhibitors; Guanidines; Humans; Infant; Infant, Newborn; Influenza A virus; Influenza B virus; Influenza, Human; Middle Aged; Neuraminidase; Oseltamivir; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Zanamivir | 2003 |
Review of the use of neuraminidase inhibitors for prophylaxis of influenza.
Topics: Acetamides; Amantadine; Antiviral Agents; Enzyme Inhibitors; Guanidines; Health Planning; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Practice Guidelines as Topic; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2003 |
Neuraminidase inhibitors for preventing and treating influenza in children.
Topics: Acetamides; Antiviral Agents; Child; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Zanamivir | 2003 |
Influenza therapy.
Topics: Acetamides; Adult; Age Factors; Amantadine; Antiviral Agents; Child; Cost-Benefit Analysis; Creatine; Disease Outbreaks; Drug Resistance, Viral; Guanidines; Humans; Influenza A virus; Influenza, Human; Kidney Failure, Chronic; Metabolic Clearance Rate; Oseltamivir; Patient Selection; Primary Prevention; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2003 |
[Clinical characteristic of the elderly in influenza infection].
Topics: Age Factors; Aged; Amantadine; Antiviral Agents; Chromatography; Enzyme Inhibitors; Guanidines; Humans; Immunoenzyme Techniques; Influenza Vaccines; Influenza, Human; Neuraminidase; Pneumonia, Viral; Prognosis; Pyrans; Reagent Kits, Diagnostic; Risk; Sialic Acids; Zanamivir | 2003 |
[Influenza virus infection in children].
Topics: Acetamides; Age Factors; Child; Child, Preschool; Enzyme Inhibitors; Guanidines; Humans; Infant; Influenza Vaccines; Influenza, Human; Japan; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2003 |
[Criteria for the use of anti-influenza agents].
Topics: Acetamides; Amantadine; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Oseltamivir; Practice Guidelines as Topic; Prodrugs; Pyrans; Sialic Acids; Time Factors; Virus Latency; Zanamivir | 2003 |
[Neuraminidase inhibitor, anti-influenzal agent--mechanism of action, and how to use clinically].
Topics: Acetamides; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Time Factors; Zanamivir | 2003 |
Neuraminidase inhibitors in patients with underlying airways disease.
Topics: Acetamides; Amantadine; Antiviral Agents; Asthma; Bronchial Spasm; Comorbidity; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Product Surveillance, Postmarketing; Pulmonary Disease, Chronic Obstructive; Pyrans; Rimantadine; Risk Factors; Sialic Acids; Zanamivir | 2002 |
Spotlight on zanamivir in influenza.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Antiviral Agents; Child; Clinical Trials as Topic; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Middle Aged; Placebos; Pyrans; Risk Factors; Severity of Illness Index; Sialic Acids; Zanamivir | 2002 |
[Neuraminidase inhibitors oseltamivir and zanamivir: new means of defence against influenza].
Topics: Acetamides; Antiviral Agents; Cost-Benefit Analysis; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Risk Factors; Seasons; Sialic Acids; Zanamivir | 2004 |
[Treatment for viral respiratory infections: Principles of action, strategies, and future prospects].
Topics: Antiviral Agents; Guanidines; Humans; Influenza, Human; Neuraminidase; Practice Patterns, Physicians'; Pyrans; Respiratory Tract Infections; Sialic Acids; Treatment Outcome; Virus Diseases; Zanamivir | 2004 |
Medical economics in the field of influenza--past, present and future.
Topics: Adult; Antiviral Agents; Child; Child, Preschool; Cost of Illness; Cost-Benefit Analysis; Guanidines; Health Care Costs; Humans; Influenza Vaccines; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Vaccination; Zanamivir | 2004 |
Neuraminidase inhibitors for treatment of influenza.
Topics: Acetamides; Antiviral Agents; Child; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2004 |
What is the best antiviral agent for influenza infection?
Topics: Acetamides; Administration, Oral; Adult; Amantadine; Antiviral Agents; Child; Contraindications; Evidence-Based Medicine; Family Practice; Guanidines; Humans; Influenza A virus; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2004 |
Influenza.
Topics: Acetamides; Adult; Amantadine; Antiviral Agents; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2003 |
[Super pathogenic avian influenza].
Topics: Acetamides; Amantadine; Animals; Antiviral Agents; Chickens; Disease Outbreaks; Guanidines; Humans; Influenza A virus; Influenza in Birds; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; Poultry Diseases; Pyrans; Sialic Acids; Zanamivir; Zoonoses | 2004 |
[Zanamivir, oseltamivir].
Topics: Acetamides; Antiviral Agents; Biological Availability; Clinical Trials as Topic; Drug Monitoring; Enzyme Inhibitors; Guanidines; Half-Life; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2004 |
Management of influenza virus infections with neuraminidase inhibitors: detection, incidence, and implications of drug resistance.
Topics: Acetamides; Animals; Drug Resistance; Enzyme Inhibitors; Guanidines; Hemagglutinins; Humans; Influenza Vaccines; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Product Surveillance, Postmarketing; Pyrans; Sialic Acids; Zanamivir | 2005 |
Influenza.
Topics: Acetamides; Adult; Amantadine; Antiviral Agents; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2004 |
Neuraminidase inhibitors for influenza.
Topics: Acetamides; Adamantane; Adult; Aged; Antiviral Agents; Child; Disease Outbreaks; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2005 |
[Anti-virals for influenza virus infection].
Topics: Acetamides; Amantadine; Animals; Antiviral Agents; Drug Utilization; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Japan; National Health Programs; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2005 |
Neuraminidase inhibitor susceptibility network position statement: antiviral resistance in influenza A/H5N1 viruses.
Topics: Acetamides; Computer Communication Networks; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Viral Matrix Proteins; Zanamivir | 2005 |
[Role of influenza virus sialidase].
Topics: Acetamides; Antiviral Agents; Apoptosis; Caspase 3; Caspases; Disease Outbreaks; Guanidines; Humans; Hydrogen-Ion Concentration; Influenza, Human; Neuraminidase; Orthomyxoviridae; Oseltamivir; Pyrans; Sialic Acids; Viral Envelope Proteins; Zanamivir | 2006 |
Neuraminidase inhibitors for preventing and treating influenza in healthy adults.
Topics: Acetamides; Amines; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2006 |
Safety of neuraminidase inhibitors for influenza.
Topics: Acetamides; Adult; Aged; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Infant; Influenza, Human; Nausea; Neuraminidase; Oseltamivir; Pyrans; Safety; Sialic Acids; Zanamivir | 2006 |
Antiviral drugs prophylaxis and treatment of influenza.
Topics: Acetamides; Animals; Antiviral Agents; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2006 |
Antiviral effects on influenza viral transmission and pathogenicity: observations from household-based trials.
Topics: Antiviral Agents; Disease Transmission, Infectious; Family Characteristics; Humans; Influenza, Human; Multicenter Studies as Topic; Oseltamivir; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome; Zanamivir | 2007 |
Antivirals in the management of an influenza pandemic.
Topics: Amantadine; Antiviral Agents; Australia; Community-Acquired Infections; Disease Outbreaks; Drug Resistance, Viral; Government Programs; Humans; Infection Control; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; World Health Organization; Zanamivir | 2006 |
Which agents should we use to treat and prevent influenza in 2006-2007?
Topics: Amantadine; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Rimantadine; Zanamivir | 2006 |
Neuraminidase inhibitors for preventing and treating influenza in children.
Topics: Acetamides; Antiviral Agents; Child; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Randomized Controlled Trials as Topic; Sialic Acids; Zanamivir | 2007 |
[Neuraminidase inhibitors and risk of H5N1 influenza].
Topics: Animals; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2007 |
Antiviral therapy and prophylaxis for influenza in children.
Topics: Adamantane; Amantadine; Antiviral Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infant; Influenza, Human; Male; Oseltamivir; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Rimantadine; Risk Assessment; Severity of Illness Index; Treatment Outcome; Zanamivir | 2007 |
[Antiviral agents for influenza].
Topics: Amantadine; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Viral Matrix Proteins; Zanamivir | 2007 |
Influenza: evolving strategies in treatment and prevention.
Topics: Aged; Amantadine; Antiviral Agents; Centers for Disease Control and Prevention, U.S.; Child, Preschool; Humans; Infant; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Oseltamivir; Practice Guidelines as Topic; Ribavirin; Rimantadine; United States; Zanamivir | 2007 |
[Threat from newly emerging influenza].
Topics: Animals; Antiviral Agents; Birds; Communicable Diseases, Emerging; Disease Outbreaks; Humans; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Influenza, Human; Oseltamivir; Zanamivir | 2007 |
Current research on drugs and vaccines for fighting bird flu.
Topics: Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Oseltamivir; Zanamivir | 2007 |
Neuraminidase inhibitor resistance in influenza viruses.
Topics: Acids, Carbocyclic; Adult; Animals; Antiviral Agents; Catalytic Domain; Child; Clinical Trials as Topic; Cyclopentanes; Drug Administration Schedule; Enzyme Inhibitors; Guanidines; Humans; Immunocompromised Host; Influenza A Virus, H5N1 Subtype; Influenza, Human; Neuraminidase; Orthomyxoviridae; Orthomyxoviridae Infections; Oseltamivir; Seasons; Sentinel Surveillance; Viral Proteins; Virulence; Zanamivir | 2007 |
Recent anti-influenza strategies in multivalent sialyloligosaccharides and sialylmimetics approaches.
Topics: Animals; Antiviral Agents; Hemagglutinins, Viral; Humans; Influenza, Human; Molecular Mimicry; Neuraminidase; Oligosaccharides; Orthomyxoviridae; Virus Attachment; Zanamivir | 2007 |
Neuraminidase inhibitors and their role in avian and pandemic influenza.
Topics: Animals; Antiviral Agents; Birds; Disease Outbreaks; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H5N1 Subtype; Influenza A Virus, H9N2 Subtype; Influenza in Birds; Influenza, Human; Mice; Neuraminidase; Oseltamivir; Zanamivir | 2007 |
Occasional review: influenza in COPD: pathogenesis, prevention, and treatment.
Topics: Amantadine; Antiviral Agents; Humans; Influenza Vaccines; Influenza, Human; Oseltamivir; Pulmonary Disease, Chronic Obstructive; Rimantadine; Zanamivir | 2007 |
The war against influenza: discovery and development of sialidase inhibitors.
Topics: Animals; Antiviral Agents; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2007 |
[Countermeasures for newly-emerging influenza].
Topics: Antiviral Agents; Communicable Diseases, Emerging; Disease Outbreaks; Enzyme Inhibitors; Humans; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2007 |
Lessons learned from the 2007-2008 cold and flu season: what worked and what was worthless.
Topics: Antiviral Agents; Causality; Common Cold; Diagnosis, Differential; Dietary Supplements; Hand Disinfection; Hospitalization; Humans; Infection Control; Influenza Vaccines; Influenza, Human; Morbidity; Nonprescription Drugs; Oseltamivir; Seasons; United States; Vaccination; Zanamivir | 2008 |
'Flu' and structure-based drug design.
Topics: Amines; Antiviral Agents; Binding Sites; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Guanidines; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Influenza, Human; Models, Molecular; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 1997 |
[Emerging infectious diseases--influenza].
Topics: Animals; Antiviral Agents; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Neuraminidase; Orthomyxoviridae; Pyrans; Serotyping; Sialic Acids; Zanamivir | 1997 |
Preclinical development of low toxicity drugs: focus on zanamivir, an anti-influenza drug.
Topics: Administration, Inhalation; Animals; Antiviral Agents; Dogs; Drug Evaluation, Preclinical; Female; Guanidines; Humans; Influenza, Human; Injections, Intravenous; Male; Mice; Pyrans; Rats; Rats, Wistar; Sialic Acids; Zanamivir | 1998 |
New approaches to influenza chemotherapy. Neuraminidase inhibitors.
Topics: Acetamides; Animals; Antiviral Agents; Drug Resistance, Microbial; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 1998 |
Underused options for preventing and treating influenza.
Topics: Adolescent; Adult; Aged; Amantadine; Antiviral Agents; Child; Child, Preschool; Drug Administration Routes; Female; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Orthomyxoviridae; Pyrans; Ribavirin; Rimantadine; Sialic Acids; Zanamivir | 1999 |
Zanamivir. A potent and selective inhibitor of influenza A and B viruses.
Topics: Animals; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 1999 |
Zanamivir: a review of clinical safety.
Topics: Animals; Antiviral Agents; Clinical Trials as Topic; Comorbidity; Drug Interactions; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 1999 |
Update on influenza and rhinovirus infections.
Topics: Acetamides; Amines; Antiviral Agents; Common Cold; Guanidines; Humans; Influenza, Human; Intercellular Adhesion Molecule-1; Neuraminidase; Oseltamivir; Oxadiazoles; Oxazoles; Picornaviridae Infections; Pyrans; Recombinant Proteins; Rhinovirus; Sialic Acids; Zanamivir | 1999 |
Zanamivir: a review of its use in influenza.
Topics: Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Microbial; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 1999 |
Effectiveness and role of zanamivir in the treatment of influenza infection.
Topics: Adult; Aged; Antiviral Agents; Clinical Trials as Topic; Female; Guanidines; Humans; Influenza, Human; Male; Middle Aged; Prognosis; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 1999 |
Prevention and early treatment of influenza in healthy adults.
Topics: Adolescent; Adult; Amantadine; Antiviral Agents; Cost-Benefit Analysis; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Middle Aged; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2000 |
Measures for control of influenza.
Topics: Amantadine; Amines; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza Vaccines; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 1999 |
[Critical review of anti-influenza drugs].
Topics: Acetamides; Adult; Antiviral Agents; Drug Resistance, Microbial; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Netherlands; Neuraminidase; Oseltamivir; Public Health; Pyrans; Sialic Acids; Zanamivir | 2000 |
Antiviral agents for treating influenza.
Topics: Acetamides; Amantadine; Antiviral Agents; Drug Administration Schedule; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2000 |
[symbol: see text] Zanamivir for influenza.
Topics: Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Zanamivir | 1999 |
Influenza virus neuraminidase inhibitors.
Topics: Acetamides; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Orthomyxoviridae; Oseltamivir; Pyrans; Sialic Acids; Treatment Outcome; Virus Replication; Zanamivir | 2000 |
Neuraminidase inhibitors for preventing and treating influenza in healthy adults.
Topics: Adult; Amantadine; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 2000 |
Zanamivir in the treatment and prevention of influenza.
Topics: Clinical Trials as Topic; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 2000 |
Epidemiology and pathogenesis of influenza.
Topics: Animals; Antigenic Variation; Antiviral Agents; Guanidines; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 1999 |
A novel approach to antiviral therapy for influenza.
Topics: Animals; Antiviral Agents; Drug Design; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 1999 |
Neuraminidase inhibitors in the treatment of influenza A and B--overview and case reports.
Topics: Acetamides; Administration, Inhalation; Adult; Aged; Aged, 80 and over; Antiviral Agents; Bronchitis; Clinical Trials as Topic; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Male; Middle Aged; Neuraminidase; Oseltamivir; Pericarditis; Pyrans; Sialic Acids; Zanamivir | 2000 |
Impact of zanamivir on antibiotic use for respiratory events following acute influenza in adolescents and adults.
Topics: Acute Disease; Administration, Inhalation; Administration, Intranasal; Adolescent; Adult; Aged; Anti-Bacterial Agents; Antiviral Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Drug Prescriptions; Guanidines; Humans; Incidence; Influenza, Human; Middle Aged; Multicenter Studies as Topic; Pyrans; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Risk Factors; Sialic Acids; Time Factors; Treatment Outcome; Zanamivir | 2000 |
Updated treatment for influenza A and B.
Topics: Acetamides; Amantadine; Antiviral Agents; Clinical Trials as Topic; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Treatment Outcome; Zanamivir | 2000 |
Influenza virus and rhinovirus-related otitis media: potential for antiviral intervention.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Antiviral Agents; Child; Child, Preschool; Clinical Trials as Topic; Eustachian Tube; Guanidines; Humans; Infant; Influenza A virus; Influenza B virus; Influenza, Human; Interferon-beta; Oseltamivir; Otitis Media; Otitis Media with Effusion; Picornaviridae Infections; Piperidines; Pressure; Pyrans; Pyridazines; Respiratory Tract Infections; Rhinovirus; Rimantadine; Sialic Acids; Superinfection; Virus Replication; Zanamivir | 2000 |
Zanamivir for the treatment of influenza A and B infection in high-risk patients: a pooled analysis of randomized controlled trials.
Topics: Administration, Inhalation; Adult; Aged; Antiviral Agents; Child; Child, Preschool; Double-Blind Method; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Male; Middle Aged; Neuraminidase; Pyrans; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Sialic Acids; Zanamivir | 2001 |
[Influenza].
Topics: Acetamides; Amantadine; Antiviral Agents; Disease Outbreaks; Guanidines; History, 18th Century; History, 19th Century; History, 20th Century; Humans; Influenza, Human; Italy; Orthomyxoviridae; Oseltamivir; Pyrans; Sialic Acids; United States; Zanamivir | 2000 |
Neuraminidase inhibitors: zanamivir and oseltamivir.
Topics: Acetamides; Antiviral Agents; Clinical Trials as Topic; Diarrhea; Enzyme Inhibitors; Guanidines; Headache; Humans; Influenza, Human; Nausea; Neuraminidase; Orthomyxoviridae; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2001 |
Prophylactic and symptomatic treatment of influenza. Current and developing options.
Topics: Acetamides; Adolescent; Adult; Aged; Antiviral Agents; Child; Child, Preschool; Guanidines; Humans; Infant; Influenza Vaccines; Influenza, Human; Middle Aged; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Time Factors; Zanamivir | 2001 |
[Antiinfluenza-drugs and the standard of the use].
Topics: Acetamides; Amantadine; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2000 |
[Neuraminidase inhibitor].
Topics: Acetamides; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2000 |
Zanamivir: a rational approach to influenza B.
Topics: Animals; Antiviral Agents; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 2001 |
Why not [symbol: see text]zanamivir?
Topics: Adult; Aged; Antiviral Agents; Guanidines; Humans; Influenza, Human; Middle Aged; Patient Selection; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2001 |
Zanamivir and oseltamivir: two new options for the treatment and prevention of influenza.
Topics: Acetamides; Animals; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2001 |
[Efficacy of inhaled zanamivir in the treatment and prevention of influenza].
Topics: Administration, Inhalation; Antiviral Agents; Clinical Trials as Topic; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 2001 |
Managing influenza: amantadine, rimantadine and beyond.
Topics: Adolescent; Adult; Aged; Amantadine; Antiviral Agents; Child; Child, Preschool; Guanidines; Humans; Infant; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Middle Aged; Neuraminidase; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2001 |
Position statement: global neuraminidase inhibitor susceptibility network.
Topics: Acetamides; Animals; Antiviral Agents; Drug Resistance; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Mutation; Neuraminidase; Orthomyxoviridae; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2001 |
Adverse cutaneous reactions to influenza vaccinations and chemotherapy.
Topics: Acetamides; Amantadine; Antiviral Agents; Drug Eruptions; Drug-Related Side Effects and Adverse Reactions; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Orthomyxoviridae; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Skin; Zanamivir | 2001 |
Zanamivir: a review of clinical safety in individuals at high risk of developing influenza-related complications.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Controlled Clinical Trials as Topic; Guanidines; Humans; Influenza, Human; Middle Aged; Nursing Homes; Product Surveillance, Postmarketing; Pyrans; Risk Factors; Sialic Acids; Zanamivir | 2001 |
Perspectives on antiviral use during pandemic influenza.
Topics: Acetamides; Amantadine; Antiviral Agents; Chemoprevention; Disease Outbreaks; Drug Resistance, Multiple, Viral; Drug Tolerance; Guanidines; Humans; Influenza A virus; Influenza, Human; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2001 |
Zanamivir: from drug design to the clinic.
Topics: Animals; Antiviral Agents; Chemoprevention; Clinical Trials as Topic; Drug Design; Drug Interactions; Drug Resistance, Multiple, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 2001 |
Treatment of influenza with neuraminidase inhibitors: virological implications.
Topics: Acetamides; Animals; Antiviral Agents; Drug Resistance, Multiple, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2001 |
Zanamivir: an update of its use in influenza.
Topics: Animals; Antiviral Agents; Drug Resistance, Microbial; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 2002 |
Neuraminidase inhibitors for the treatment and prevention of influenza.
Topics: Acetamides; Drug Resistance, Viral; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Treatment Outcome; Zanamivir | 2002 |
Influenza in the acute hospital setting.
Topics: Acetamides; Amantadine; Antiviral Agents; Cross Infection; Disease Outbreaks; Guanidines; Hospitals; Humans; Influenza Vaccines; Influenza, Human; Nursing Staff, Hospital; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Vaccination; Virginia; Zanamivir | 2002 |
Zanamivir for the treatment of influenza in adults: a systematic review and economic evaluation.
Topics: Adult; Antiviral Agents; Cost-Benefit Analysis; Guanidines; Humans; Influenza, Human; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Treatment Outcome; United Kingdom; Zanamivir | 2002 |
67 trial(s) available for zanamivir and Grippe
Article | Year |
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Lessons from resistance analysis in clinical trials of IV zanamivir.
Topics: Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2023 |
Efficacy of oseltamivir compared with zanamivir in COPD patients with seasonal influenza virus infection: a randomized controlled trial.
Topics: Antiviral Agents; Enzyme Inhibitors; Female; Humans; Influenza, Human; Male; Middle Aged; Neuraminidase; Oseltamivir; Pulmonary Disease, Chronic Obstructive; Zanamivir | 2020 |
Factors associated with non-persistence to oral and inhaled antiviral therapies for seasonal influenza: a secondary analysis of a double-blind, multicentre, randomised clinical trial.
Topics: Administration, Inhalation; Administration, Oral; Antiviral Agents; Double-Blind Method; Female; France; Humans; Influenza, Human; Kaplan-Meier Estimate; Lost to Follow-Up; Male; Medication Adherence; Multivariate Analysis; Oseltamivir; Proportional Hazards Models; Treatment Outcome; Zanamivir | 2017 |
Duration of fever and other symptoms after the inhalation of laninamivir octanoate hydrate; comparison of the 2011/12 to 2015/16 Japanese influenza seasons.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Antiviral Agents; Child; Enzyme Inhibitors; Female; Fever; Guanidines; Humans; Influenza, Human; Male; Middle Aged; Neuraminidase; Pregnancy; Product Surveillance, Postmarketing; Pyrans; Sialic Acids; Treatment Outcome; Young Adult; Zanamivir | 2017 |
Intravenous Zanamivir in Hospitalized Patients With Influenza.
Topics: Adolescent; Antiviral Agents; Child; Child, Preschool; Female; Hospitalization; Humans; Infant; Influenza, Human; Infusions, Intravenous; Male; Neutropenia; Viral Load; Zanamivir | 2017 |
Clinical and virologic effects of four neuraminidase inhibitors in influenza A virus-infected children (aged 4-12 years): an open-label, randomized study in Japan.
Topics: Acids, Carbocyclic; Antiviral Agents; Child; Child, Preschool; Cyclopentanes; Female; Guanidines; Humans; Influenza A virus; Influenza, Human; Japan; Male; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Time Factors; Treatment Outcome; Zanamivir | 2018 |
Pharmacokinetics of zanamivir following intravenous administration to subjects with and without renal impairment.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Creatinine; Female; Humans; Influenza, Human; Infusions, Intravenous; Male; Metabolic Clearance Rate; Middle Aged; Renal Insufficiency; Young Adult; Zanamivir | 2013 |
Safety, tolerability and pharmacokinetics of orally inhaled zanamivir: a randomized study comparing Rotacap/Rotahaler and Rotadisk/Diskhaler in healthy adults.
Topics: Administration, Inhalation; Adult; Antiviral Agents; Female; Healthy Volunteers; Humans; Influenza, Human; Male; Young Adult; Zanamivir | 2013 |
Laninamivir octanoate for post-exposure prophylaxis of influenza in household contacts: a randomized double blind placebo controlled trial.
Topics: Administration, Inhalation; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Disease Transmission, Infectious; Double-Blind Method; Family Characteristics; Female; Guanidines; Humans; Infant; Influenza, Human; Male; Middle Aged; Placebos; Post-Exposure Prophylaxis; Pyrans; Sialic Acids; Zanamivir | 2013 |
Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Female; Hospitalization; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Treatment Outcome; Viral Load; Zanamivir | 2014 |
The duration of fever and other symptoms after the initiation of laninamivir octanoate hydrate in the Japanese 2011-2012 influenza season.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Female; Fever; Guanidines; Humans; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Inhibitory Concentration 50; Male; Middle Aged; Pyrans; Sialic Acids; Young Adult; Zanamivir | 2014 |
Clinical effects of oseltamivir, zanamivir, laninamivir and peramivir on seasonal influenza infection in outpatients in Japan during the winter of 2012-2013.
Topics: Acids, Carbocyclic; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Cyclopentanes; Enzyme Inhibitors; Female; Guanidines; Humans; Infant; Influenza, Human; Japan; Male; Middle Aged; Neuraminidase; Oseltamivir; Outpatients; Pyrans; Sialic Acids; Time Factors; Treatment Outcome; Young Adult; Zanamivir | 2013 |
Continued effectiveness of laninamivir octanate hydrate for influenza treatment in Japan: comparison between the 2011-2012 and 2012-2013 influenza seasons.
Topics: Antiviral Agents; Child; Disease Outbreaks; Female; Guanidines; Humans; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Japan; Male; Microbial Sensitivity Tests; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2014 |
Evaluation of safety and efficacy of intravenous zanamivir in the treatment of hospitalized Japanese patients with influenza: an open-label, single-arm study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Injections, Intravenous; Male; Middle Aged; Neuraminidase; Patient Safety; Treatment Outcome; Viral Proteins; Zanamivir | 2015 |
Zanamivir versus trivalent split virus influenza vaccine: a pilot randomized trial.
Topics: Adult; Antiviral Agents; Canada; Female; Hemagglutination Inhibition Tests; Humans; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Pilot Projects; Seasons; Young Adult; Zanamivir | 2015 |
Clinical outcome of laninamivir octanoate hydrate for influenza in the 2013-2014 Japanese season.
Topics: Antiviral Agents; Child; Female; Guanidines; Humans; Influenza A virus; Influenza, Human; Inhibitory Concentration 50; Male; Pyrans; Sialic Acids; Zanamivir | 2015 |
Long-acting Neuraminidase Inhibitor Laninamivir Octanoate as Post-exposure Prophylaxis for Influenza.
Topics: Administration, Inhalation; Adolescent; Adult; Antiviral Agents; Child; Double-Blind Method; Enzyme Inhibitors; Family Characteristics; Female; Guanidines; Humans; Influenza, Human; Male; Middle Aged; Neuraminidase; Post-Exposure Prophylaxis; Pyrans; Sialic Acids; Young Adult; Zanamivir | 2016 |
Phenotypic and genotypic analysis of influenza viruses isolated from adult subjects during a phase II study of intravenous zanamivir in hospitalised subjects.
Topics: Administration, Intravenous; Adult; Drug Resistance, Viral; Genotype; Hemagglutinins; Hospitalization; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Inhibitory Concentration 50; Neuraminidase; Phenotype; Sequence Analysis, DNA; Zanamivir | 2016 |
Clinical efficacy of laninamivir and peramivir in patients with seasonal influenza: a randomized clinical trial.
Topics: Acids, Carbocyclic; Adult; Antiviral Agents; Cyclopentanes; Female; Guanidines; Humans; Influenza, Human; Japan; Male; Middle Aged; Oseltamivir; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2017 |
Inhaled Laninamivir Octanoate as Prophylaxis for Influenza in Children.
Topics: Administration, Inhalation; Age Factors; Antiviral Agents; Child; Child, Preschool; Communicable Disease Control; Confidence Intervals; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Family Characteristics; Follow-Up Studies; Guanidines; Humans; Influenza, Human; Japan; Monitoring, Physiologic; Pyrans; Risk Assessment; Sialic Acids; Treatment Outcome; Zanamivir | 2016 |
Intravenous zanamivir or oral oseltamivir for hospitalised patients with influenza: an international, randomised, double-blind, double-dummy, phase 3 trial.
Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Double-Blind Method; Female; Hospitalization; Humans; Influenza, Human; Male; Middle Aged; Oseltamivir; Treatment Outcome; Young Adult; Zanamivir | 2017 |
Long-acting neuraminidase inhibitor laninamivir octanoate (CS-8958) versus oseltamivir as treatment for children with influenza virus infection.
Topics: Administration, Inhalation; Administration, Oral; Antiviral Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Male; Neuraminidase; Oseltamivir; Treatment Outcome; Virus Shedding; Zanamivir | 2010 |
Long-acting neuraminidase inhibitor laninamivir octanoate versus oseltamivir for treatment of influenza: A double-blind, randomized, noninferiority clinical trial.
Topics: Administration, Inhalation; Administration, Oral; Adult; Aged; Antiviral Agents; Drug Administration Schedule; Female; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Male; Middle Aged; Oseltamivir; Pyrans; Sialic Acids; Viral Load; Zanamivir | 2010 |
Efficacy of oseltamivir-zanamivir combination compared to each monotherapy for seasonal influenza: a randomized placebo-controlled trial.
Topics: Adult; Antiviral Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Influenza, Human; Male; Middle Aged; Oseltamivir; Treatment Outcome; Zanamivir | 2010 |
A randomized, controlled trial comparing traditional herbal medicine and neuraminidase inhibitors in the treatment of seasonal influenza.
Topics: Adult; Antiviral Agents; Cytokines; Drugs, Chinese Herbal; Enzyme Inhibitors; Female; Fever; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Male; Middle Aged; Neuraminidase; Oseltamivir; Statistics, Nonparametric; Treatment Outcome; Zanamivir | 2012 |
Effect of a single inhalation of laninamivir octanoate in children with influenza.
Topics: Administration, Inhalation; Adolescent; Child; Child, Preschool; Female; Fever; Guanidines; Humans; Influenza, Human; Male; Neuraminidase; Pyrans; Sialic Acids; Surveys and Questionnaires; Treatment Outcome; Zanamivir | 2012 |
Clinical effectiveness of neuraminidase inhibitors--oseltamivir, zanamivir, laninamivir, and peramivir--for treatment of influenza A(H3N2) and A(H1N1)pdm09 infection: an observational study in the 2010-2011 influenza season in Japan.
Topics: Acids, Carbocyclic; Antiviral Agents; Child; Child, Preschool; Cyclopentanes; Disease Outbreaks; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Japan; Male; Neuraminidase; Oseltamivir; Treatment Outcome; Zanamivir | 2012 |
A randomized double-blind controlled study of laninamivir compared with oseltamivir for the treatment of influenza in patients with chronic respiratory diseases.
Topics: Adult; Aged; Antiviral Agents; Asthma; Chronic Disease; Double-Blind Method; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2013 |
Oseltamivir-zanamivir bitherapy compared to oseltamivir monotherapy in the treatment of pandemic 2009 influenza A(H1N1) virus infections.
Topics: Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; France; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Nasal Mucosa; Oseltamivir; Treatment Outcome; Virus Shedding; Young Adult; Zanamivir | 2012 |
Effect of oseltamivir, zanamivir or oseltamivir-zanamivir combination treatments on transmission of influenza in households.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Cough; Drug Therapy, Combination; Enzyme Inhibitors; Family Characteristics; Female; Fever; Follow-Up Studies; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Male; Middle Aged; Multivariate Analysis; Neuraminidase; Oseltamivir; Time Factors; Young Adult; Zanamivir | 2012 |
Utility of Maoto in an influenza season where reduced effectiveness of oseltamivir was observed - a clinical, non-randomized study in children.
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Age Factors; Alphainfluenzavirus; Antiviral Agents; Betainfluenzavirus; Child; Child, Preschool; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Humans; Infant; Influenza, Human; Male; Oseltamivir; Seasons; Treatment Outcome; Zanamivir | 2012 |
Oseltamivir and inhaled zanamivir as influenza prophylaxis in Thai health workers: a randomized, double-blind, placebo-controlled safety trial over 16 weeks.
Topics: Administration, Inhalation; Adult; Antiviral Agents; Chemoprevention; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Health Personnel; Humans; Influenza, Human; Male; Middle Aged; Oseltamivir; Placebos; Thailand; Young Adult; Zanamivir | 2013 |
Virus susceptibility analyses from a phase IV clinical trial of inhaled zanamivir treatment in children infected with influenza.
Topics: Amino Acid Substitution; Drug Resistance, Viral; Humans; Influenza, Human; Molecular Sequence Data; Mutation; Neuraminidase; Polymerase Chain Reaction; Viral Proteins; Zanamivir | 2013 |
Utility of zanamivir for chemoprophylaxis of concomitant influenza A and B in a complex continuing care population.
Topics: Aged; Aged, 80 and over; Antiviral Agents; Comorbidity; Cross Infection; Disease Outbreaks; Female; Guanidines; Hospital Bed Capacity, 500 and over; Hospital Units; Hospitals, Urban; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Long-Term Care; Male; Middle Aged; Ontario; Premedication; Pyrans; Rehabilitation Centers; Safety; Sialic Acids; Zanamivir | 2002 |
Zanamivir prophylaxis: an effective strategy for the prevention of influenza types A and B within households.
Topics: Adolescent; Adult; Antiviral Agents; Chemoprevention; Child; Child, Preschool; Disease Transmission, Infectious; Double-Blind Method; Family Characteristics; Female; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Male; Microbial Sensitivity Tests; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2002 |
Neuraminidase inhibitors in the management of influenza--experience of an outpatient practice.
Topics: Acetamides; Aged; Ambulatory Care; Antiviral Agents; Child; Enzyme Inhibitors; Fibrinogen; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2002 |
Drug under test: influenza--Relenza in daily practice. Experience during the influenza season 1999/2000.
Topics: Antiviral Agents; Drug Tolerance; Fever; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Pharyngitis; Pyrans; Respiratory Tract Infections; Risk; Seasons; Sialic Acids; Treatment Outcome; Zanamivir | 2002 |
Zanamivir: a significant reduction in viral load during treatment in military conscripts with influenza.
Topics: Administration, Oral; Adult; Base Sequence; Confidence Intervals; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Finland; Follow-Up Studies; Guanidines; Humans; Influenza, Human; Male; Military Personnel; Molecular Sequence Data; Orthomyxoviridae; Polymerase Chain Reaction; Probability; Pyrans; Reference Values; RNA, Viral; Severity of Illness Index; Sialic Acids; Treatment Outcome; Viral Load; Zanamivir | 2003 |
Safety and efficacy of once daily intranasal zanamivir in preventing experimental human influenza A infection.
Topics: Administration, Intranasal; Adolescent; Adult; Antiviral Agents; Double-Blind Method; Female; Guanidines; Humans; Influenza A virus; Influenza, Human; Male; Pyrans; Sialic Acids; Zanamivir | 1999 |
Safety and efficacy of nebulized zanamivir in hospitalized patients with serious influenza.
Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanidines; Humans; Influenza, Human; Male; Middle Aged; Nebulizers and Vaporizers; Pyrans; Respiratory Therapy; Rimantadine; Sialic Acids; Zanamivir | 2003 |
Viral shedding in children with influenza virus infections treated with neuraminidase inhibitors.
Topics: Acetamides; Animals; Antiviral Agents; Cell Line; Child; Child, Preschool; Chlorocebus aethiops; Guanidines; Humans; Infant; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Treatment Outcome; Vero Cells; Virus Shedding; Zanamivir | 2005 |
Zanamivir treatment is equally effective for both influenza A and influenza B.
Topics: Administration, Inhalation; Adolescent; Adult; Antiviral Agents; Female; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Male; Middle Aged; Treatment Outcome; Zanamivir | 2007 |
Efficacy and safety of inhaled zanamivir in the prevention of influenza in community-dwelling, high-risk adult and adolescent subjects: a 28-day, multicenter, randomized, double-blind, placebo-controlled trial.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Double-Blind Method; Europe; Female; Humans; Influenza, Human; Male; Middle Aged; North America; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Zanamivir | 2007 |
A comparison of the effectiveness of zanamivir and oseltamivir for the treatment of influenza A and B.
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Female; Fever; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Japan; Male; Oseltamivir; Treatment Outcome; Zanamivir | 2008 |
Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenzavirus infections. GG167 Influenza Study Group.
Topics: Administration, Inhalation; Administration, Intranasal; Adolescent; Adult; Antiviral Agents; Double-Blind Method; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Nose; Pyrans; Sialic Acids; Time Factors; Treatment Outcome; Zanamivir | 1997 |
Effects of the neuraminidase inhibitor zanamavir on otologic manifestations of experimental human influenza.
Topics: Administration, Intranasal; Adult; Antiviral Agents; Double-Blind Method; Ear Diseases; Ear, Middle; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Nasal Lavage Fluid; Pressure; Pyrans; Sialic Acids; Zanamivir | 1997 |
Efficacy of zanamivir for chemoprophylaxis of nursing home influenza outbreaks.
Topics: Aged; Antiviral Agents; Disease Outbreaks; Female; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Male; Nursing Homes; Prospective Studies; Pyrans; Random Allocation; Rimantadine; Sialic Acids; Treatment Outcome; Wisconsin; Zanamivir | 1998 |
Randomised trial of efficacy and safety of inhaled zanamivir in treatment of influenza A and B virus infections. The MIST (Management of Influenza in the Southern Hemisphere Trialists) Study Group.
Topics: Administration, Inhalation; Adolescent; Adult; Antiviral Agents; Double-Blind Method; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Pyrans; Safety; Sialic Acids; Treatment Outcome; Zanamivir | 1998 |
Safety and efficacy of intravenous zanamivir in preventing experimental human influenza A virus infection.
Topics: Adolescent; Adult; Antiviral Agents; Double-Blind Method; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza A virus; Influenza, Human; Male; Nasal Mucosa; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 1999 |
Efficacy and safety of the neuraminidase inhibitor zanamivirin the treatment of influenza A and B virus infections.
Topics: Adult; Antiviral Agents; Double-Blind Method; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Male; Neuraminidase; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 1999 |
Zanamivir in the prevention of influenza among healthy adults: a randomized controlled trial.
Topics: Adult; Aged; Antiviral Agents; Double-Blind Method; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza, Human; Male; Middle Aged; Neuraminidase; Pyrans; Seasons; Sialic Acids; Treatment Outcome; Zanamivir | 1999 |
Nasal cytokine and chemokine responses in experimental influenza A virus infection: results of a placebo-controlled trial of intravenous zanamivir treatment.
Topics: Antiviral Agents; Body Temperature; Chemokines; Cytokines; Double-Blind Method; Guanidines; Humans; Influenza A virus; Influenza, Human; Injections, Intravenous; Male; Nasal Lavage Fluid; Neuraminidase; Placebos; Pyrans; Sialic Acids; Time Factors; Zanamivir | 1999 |
[Flu and antiviral agents....].
Topics: Acetamides; Administration, Intranasal; Administration, Oral; Adolescent; Adult; Aged; Antiviral Agents; Double-Blind Method; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Neuraminidase; Oseltamivir; Placebos; Pyrans; Risk Factors; Sialic Acids; Zanamivir | 2000 |
Safety and efficacy of the neuraminidase inhibitor zanamivir in treating influenza virus infection in adults: results from Japan. GG167 Group.
Topics: Adult; Antiviral Agents; Double-Blind Method; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 1999 |
A population pharmacokinetic analysis of zanamivir in subjects with experimental and naturally occurring influenza: effects of formulation and route of administration.
Topics: Administration, Inhalation; Administration, Intranasal; Adult; Algorithms; Antiviral Agents; Double-Blind Method; Female; Guanidines; Humans; Influenza, Human; Male; Models, Biological; Pyrans; Sialic Acids; Zanamivir | 2000 |
Short-term treatment with zanamivir to prevent influenza: results of a placebo-controlled study.
Topics: Administration, Inhalation; Administration, Intranasal; Adolescent; Adult; Aged; Antiviral Agents; Double-Blind Method; Drug Administration Schedule; Female; Guanidines; Humans; Influenza, Human; Male; Middle Aged; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2000 |
Clinical efficacy and safety of the orally inhaled neuraminidase inhibitor zanamivir in the treatment of influenza: a randomized, double-blind, placebo-controlled European study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Double-Blind Method; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Middle Aged; Neuraminidase; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2000 |
Rapid antiviral effect of inhaled zanamivir in the treatment of naturally occurring influenza in otherwise healthy adults.
Topics: Administration, Inhalation; Adult; Antiviral Agents; Canada; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 2000 |
Zanamivir for treatment of symptomatic influenza A and B infection in children five to twelve years of age: a randomized controlled trial.
Topics: Administration, Inhalation; Antiviral Agents; Child; Child, Preschool; Double-Blind Method; Female; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Male; Patient Compliance; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2000 |
Randomized, placebo-controlled studies of inhaled zanamivir in the treatment of influenza A and B: pooled efficacy analysis.
Topics: Antiviral Agents; Double-Blind Method; Fever; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Nebulizers and Vaporizers; Prospective Studies; Pyrans; Sialic Acids; Zanamivir | 1999 |
Impact of zanamivir treatment on productivity, health status and healthcare resource use in patients with influenza. Zanamivir Study Group.
Topics: Adult; Antiviral Agents; Double-Blind Method; Efficiency; Female; Guanidines; Health Care Rationing; Health Status; Humans; Influenza, Human; Male; Pyrans; Sialic Acids; Zanamivir | 2000 |
Cost effectiveness of zanamivir for the treatment of influenza in a high risk population in Australia.
Topics: Antiviral Agents; Cost-Benefit Analysis; Double-Blind Method; Guanidines; Health Care Costs; Humans; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 2000 |
Inhaled zanamivir for the prevention of influenza in families. Zanamivir Family Study Group.
Topics: Administration, Inhalation; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Disease Transmission, Infectious; Double-Blind Method; Drug Resistance, Microbial; Family Health; Female; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Male; Neuraminidase; Prospective Studies; Pyrans; RNA, Viral; Sequence Analysis, RNA; Sialic Acids; Zanamivir | 2000 |
Utility of zanamivir for chemoprophylaxis of concomitant influenza A and B in a complex continuing-care population.
Topics: Administration, Inhalation; Aged; Antiviral Agents; Female; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Male; Pyrans; Sialic Acids; Zanamivir | 2001 |
Comparison of elderly people's technique in using two dry powder inhalers to deliver zanamivir: randomised controlled trial.
Topics: Administration, Inhalation; Aged; Aged, 80 and over; Antiviral Agents; Drug Delivery Systems; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza, Human; Male; Neuraminidase; Powders; Pyrans; Sialic Acids; Zanamivir | 2001 |
Diagnosis of influenza in the community: relationship of clinical diagnosis to confirmed virological, serologic, or molecular detection of influenza.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Antibodies, Viral; Community-Acquired Infections; Double-Blind Method; Female; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Male; Middle Aged; Predictive Value of Tests; Pyrans; Reverse Transcriptase Polymerase Chain Reaction; Sialic Acids; Virus Cultivation; Zanamivir | 2001 |
The use of zanamivir to treat influenza A and B infection after allogeneic stem cell transplantation.
Topics: Adolescent; Adult; Antiviral Agents; Female; Guanidines; Hematologic Neoplasms; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Male; Myelodysplastic Syndromes; Pyrans; Sialic Acids; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome; Zanamivir | 2002 |
471 other study(ies) available for zanamivir and Grippe
Article | Year |
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Syntheses of triazole-modified zanamivir analogues via click chemistry and anti-AIV activities.
Topics: Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Models, Molecular; Neuraminidase; Pyrans; Sialic Acids; Structure-Activity Relationship; Triazoles; Zanamivir | 2006 |
Efficacy of orally administered T-705 on lethal avian influenza A (H5N1) virus infections in mice.
Topics: Amides; Animals; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Lung; Mice; Mice, Inbred BALB C; Oseltamivir; Oxygen; Pyrazines; Survival Analysis; Virus Replication | 2007 |
Synthesis and anti-influenza activities of carboxyl alkoxyalkyl esters of 4-guanidino-Neu5Ac2en (zanamivir).
Topics: Administration, Oral; Animals; Cell Line; Disease Models, Animal; Dogs; Drug Design; Humans; Influenza A virus; Influenza Vaccines; Influenza, Human; Infusions, Parenteral; Inhibitory Concentration 50; Mice; Ribavirin; Zanamivir | 2007 |
CS-8958, a prodrug of the new neuraminidase inhibitor R-125489, shows long-acting anti-influenza virus activity.
Topics: Animals; Antiviral Agents; Cell Line; Dogs; HeLa Cells; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Mice; Neuraminidase; Prodrugs; Zanamivir | 2009 |
Detection of E119V and E119I mutations in influenza A (H3N2) viruses isolated from an immunocompromised patient: challenges in diagnosis of oseltamivir resistance.
Topics: Antiviral Agents; Cells, Cultured; Child, Preschool; Drug Resistance, Viral; Genetic Testing; Humans; Immunocompromised Host; Influenza A Virus, H3N2 Subtype; Influenza, Human; Male; Molecular Sequence Data; Neuraminidase; Oseltamivir; Point Mutation; Sequence Analysis, DNA | 2010 |
Assessment of pandemic and seasonal influenza A (H1N1) virus susceptibility to neuraminidase inhibitors in three enzyme activity inhibition assays.
Topics: Acids, Carbocyclic; Animals; Cell Line; Cyclopentanes; Dogs; Enzyme Assays; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Inhibitory Concentration 50; Neuraminidase; Oseltamivir; Zanamivir | 2010 |
Intramolecular ion-pair prodrugs of zanamivir and guanidino-oseltamivir.
Topics: Administration, Oral; Antiviral Agents; Carbon Dioxide; Cell Line; Drug Evaluation, Preclinical; Enzyme Inhibitors; Esters; Guanidine; Humans; Hydrophobic and Hydrophilic Interactions; Influenza A virus; Influenza, Human; Ions; Molecular Structure; Naphthols; Neuraminidase; Oseltamivir; Prodrugs; Zanamivir | 2011 |
Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors.
Topics: Acids, Carbocyclic; Animals; Antiviral Agents; Cyclopentanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Neuraminidase; Rabbits; Structure-Activity Relationship | 2016 |
Boronic Acid Modifications Enhance the Anti-Influenza A Virus Activities of Novel Quindoline Derivatives.
Topics: Alkaloids; Animals; Antiviral Agents; Boronic Acids; Cell Line; Female; Humans; Indoles; Influenza A virus; Influenza, Human; Mice; NF-kappa B; Orthomyxoviridae Infections; Quinolines; Signal Transduction | 2017 |
Structural and Functional Analysis of Anti-Influenza Activity of 4-, 7-, 8- and 9-Deoxygenated 2,3-Difluoro- N-acetylneuraminic Acid Derivatives.
Topics: Antiviral Agents; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Structure-Activity Relationship | 2018 |
Discovery of Aryl Benzoyl Hydrazide Derivatives as Novel Potent Broad-Spectrum Inhibitors of Influenza A Virus RNA-Dependent RNA Polymerase (RdRp).
Topics: Animals; Antiviral Agents; Humans; Hydrazines; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza, Human; Mice; RNA-Dependent RNA Polymerase; Virus Replication | 2022 |
Comparison of the incidence of bleeding between baloxavir marboxil and other anti-influenza drugs among outpatients with influenza virus infection: A retrospective cohort study using an employment-based health insurance claims database in Japan.
Topics: Antiviral Agents; Communicable Diseases; Dibenzothiepins; Employment; Humans; Incidence; Influenza, Human; Insurance, Health; Japan; Morpholines; Oseltamivir; Outpatients; Pyridones; Retrospective Studies; Triazines; Zanamivir | 2022 |
Zanamivir aqueous solution in severe influenza: A global Compassionate Use Program, 2009-2019.
Topics: Antiviral Agents; Compassionate Use Trials; Enzyme Inhibitors; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2022 |
Genetic and biological properties of H10N3 avian influenza viruses: A potential pandemic candidate?
Topics: Animals; Chick Embryo; Chickens; Humans; Influenza A Virus, H5N1 Subtype; Influenza A Virus, H7N9 Subtype; Influenza in Birds; Influenza, Human; Mammals; Mice; Neuraminidase; Oseltamivir; Pandemics; Phylogeny; Poultry; Rodent Diseases; Zanamivir | 2022 |
Inhaled Zanamivir vs Oral Oseltamivir to Prevent Influenza-related Hospitalization or Death: A Nationwide Population-based Quasi-experimental Study.
Topics: Antiviral Agents; Cohort Studies; Hospitalization; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2022 |
Characterization of influenza B viruses with reduced susceptibility to influenza neuraminidase inhibitors.
Topics: Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2022 |
Duration of fever and other symptoms after the inhalation of laninamivir octanoate hydrate: A study of the 2017/18 and 2018/19 seasons and comparison with the 2011/12 to 2016/17 Japanese influenza seasons.
Topics: Antiviral Agents; Fever; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Japan; Neuraminidase; Pyrans; Seasons; Sialic Acids; Zanamivir | 2022 |
Is Inhaled Zanamivir Non-inferior to Oral Oseltamivir in the Treatment of Outpatients With Influenza?
Topics: Antiviral Agents; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Outpatients; Zanamivir | 2022 |
Response to "Inhaled Zanamivir versus Oral Oseltamivir to Prevent Influenza-related Hospitalization or Death: A Nationwide Population-based Quasi-experimental Study".
Topics: Antiviral Agents; Hospitalization; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2022 |
In Silico Studies Reveal Peramivir and Zanamivir as an Optimal Drug Treatment Even If H7N9 Avian Type Influenza Virus Acquires Further Resistance.
Topics: Acids, Carbocyclic; Antiviral Agents; Arginine; Benserazide; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H7N9 Subtype; Influenza, Human; Molecular Docking Simulation; Mutation; Neuraminidase; Oseltamivir; Zanamivir | 2022 |
Report on influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza during 2020-2021.
Topics: Antiviral Agents; Australia; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; World Health Organization; Zanamivir | 2022 |
Effect of neuraminidase inhibitor (oseltamivir) treatment on outcome of hospitalised influenza patients, surveillance data from 11 EU countries, 2010 to 2020.
Topics: Aged; Antiviral Agents; Enzyme Inhibitors; Guanidines; Hospital Mortality; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Treatment Outcome; Zanamivir | 2023 |
Factors associated with viral RNA shedding and evaluation of potential viral infectivity at returning to school in influenza outpatients after treatment with baloxavir marboxil and neuraminidase inhibitors during 2013/2014-2019/2020 seasons in Japan: an o
Topics: Adult; Antiviral Agents; Child; Enzyme Inhibitors; Humans; Influenza, Human; Japan; Neuraminidase; Oseltamivir; Outpatients; RNA, Viral; Seasons; Zanamivir | 2023 |
Dual-Action Heteromultivalent Glycopolymers Stringently Block and Arrest Influenza A Virus Infection
Topics: Alphainfluenzavirus; Antiviral Agents; Glycosylation; Humans; Influenza, Human; Polymers; Zanamivir | 2023 |
A five-day treatment course of zanamivir for the flu with a single, self-administered, painless microneedle array patch: Revolutionizing delivery of poorly membrane-permeable therapeutics.
Topics: Animals; Antiviral Agents; Gelatin; Humans; Influenza, Human; Rats; Swine; Trehalose; Zanamivir | 2023 |
Targeting the Human Influenza a Virus: The Methods, Limitations, and Pitfalls of Virtual Screening for Drug-like Candidates Including Scaffold Hopping and Compound Profiling.
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Prospective Studies; Zanamivir | 2023 |
An armed anti-immunoglobulin light chain nanobody protects mice against influenza A and B infections.
Topics: Animals; Humans; Immunoglobulin Light Chains; Influenza, Human; Mice; Mice, Inbred BALB C; Neuraminidase; Oseltamivir; Zanamivir | 2023 |
Resistance profiles for the investigational neuraminidase inhibitor AV5080 in influenza A and B viruses.
Topics: Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Guanidine; Guanidines; Herpesvirus 1, Cercopithecine; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Influenza A Virus, H7N9 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2023 |
Report on influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza during 2022.
Topics: Animals; Antiviral Agents; Australia; Chickens; Drug Resistance, Viral; Female; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza Vaccines; Influenza, Human; Oseltamivir; World Health Organization; Zanamivir | 2023 |
Antiviral drugs for influenza for 2023-2024.
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2023 |
Comparison chart: Antiviral drugs for influenza for 2023-2024.
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2023 |
Clinical outcomes of patients treated with intravenous zanamivir for severe influenza A(H1N1)pdm09 infection: a case report series.
Topics: Antiviral Agents; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Zanamivir | 2019 |
Population Pharmacokinetic/Pharmacodynamic Analysis of Intravenous Zanamivir in Healthy Adults and Hospitalized Adult and Pediatric Subjects With Influenza.
Topics: Administration, Intravenous; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Datasets as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glomerular Filtration Rate; Healthy Volunteers; Hospitalization; Humans; Infant; Influenza A virus; Influenza, Human; Male; Middle Aged; Models, Biological; Multicenter Studies as Topic; Neuraminidase; Renal Elimination; Time Factors; United States; Viral Load; Young Adult; Zanamivir | 2020 |
Molecular pathway of influenza pan-neuraminidase inhibitor resistance in an immunocompromised patient.
Topics: Aged; Antiviral Agents; Drug Resistance, Multiple, Viral; Enzyme Inhibitors; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Transplant Recipients; Zanamivir | 2019 |
Assessment of adverse events related to anti-influenza neuraminidase inhibitors using the FDA adverse event reporting system and online patient reviews.
Topics: Acids, Carbocyclic; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Female; Guanidines; Humans; Infant; Infant, Newborn; Influenza, Human; Internet; Male; Middle Aged; Neuraminidase; Odds Ratio; Oseltamivir; Patient Participation; Pyrans; Risk Factors; Sialic Acids; United States; United States Food and Drug Administration; Young Adult; Zanamivir | 2020 |
Association of moderately abnormal behavior and administered neuraminidase inhibitors.
Topics: Acids, Carbocyclic; Adolescent; Antiviral Agents; Child; Cyclopentanes; Enzyme Inhibitors; Guanidines; Humans; Illness Behavior; Influenza, Human; Japan; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Young Adult; Zanamivir | 2020 |
Favipiravir and Zanamivir Cleared Infection with Influenza B in a Severely Immunocompromised Child.
Topics: Amides; Antiviral Agents; Child; Humans; Influenza, Human; Pyrazines; Zanamivir | 2020 |
Report on influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza in 2018.
Topics: Animals; Antigens, Viral; Antiviral Agents; Australia; Chickens; Drug Resistance, Viral; Humans; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Oseltamivir; Phylogeny; World Health Organization; Zanamivir | 2020 |
Development of Novel Anti-influenza Thiazolides with Relatively Broad-Spectrum Antiviral Potentials.
Topics: Antiviral Agents; Drug Resistance, Viral; Humans; Influenza, Human; Orthomyxoviridae; Orthomyxoviridae Infections; Oseltamivir; Zanamivir | 2020 |
Laninamivir-Interferon Lambda 1 Combination Treatment Promotes Resistance by Influenza A Virus More Rapidly than Laninamivir Alone.
Topics: Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Interferons; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 2020 |
Topology-Matching Design of an Influenza-Neutralizing Spiky Nanoparticle-Based Inhibitor with a Dual Mode of Action.
Topics: Animals; Antiviral Agents; Dogs; Drug Design; Glycerol; Humans; Influenza A virus; Influenza, Human; Lactose; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Molecular Structure; Nanoparticles; Particle Size; Polymers; Sialic Acids; Surface Properties; Virus Replication; Zanamivir | 2020 |
Detection of a Peramivir-Resistant Influenza B/Yamagata-Lineage Virus Imported from Indonesia in Aichi, Japan, March 2019.
Topics: Acids, Carbocyclic; Adult; Antiviral Agents; Dibenzothiepins; Drug Resistance, Viral; Guanidines; Humans; Indonesia; Influenza B virus; Influenza, Human; Japan; Male; Microbial Sensitivity Tests; Morpholines; Mutation; Neuraminidase; Pyrans; Pyridones; Sialic Acids; Triazines; Zanamivir | 2020 |
[Review of current and future directions of antiviral therapy of influenza and acute respiratory viral infections in Russia].
Topics: Antiviral Agents; Drug Resistance, Viral; Humans; Influenza, Human; Oseltamivir; Russia; Zanamivir | 2019 |
Characterization of neuraminidase inhibitor-resistant influenza virus isolates from immunocompromised patients in the Republic of Korea.
Topics: Acids, Carbocyclic; Adult; Amino Acid Substitution; Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Female; Guanidines; Humans; Immunocompromised Host; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation; Neuraminidase; Oropharynx; Oseltamivir; Phylogeny; Republic of Korea; Sequence Analysis, DNA; Zanamivir | 2020 |
Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenza.
Topics: Antiviral Agents; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Rimantadine; Viral Matrix Proteins; Zanamivir | 2020 |
Profile and generation of reduced neuraminidase inhibitor susceptibility in highly pathogenic avian influenza H7N9 virus from human cases in Mainland of China, 2016-2019.
Topics: Amino Acid Substitution; Animals; Antiviral Agents; Birds; Drug Resistance, Viral; Enzyme Inhibitors; Gene Expression; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H7N9 Subtype; Influenza in Birds; Influenza, Human; Microbial Sensitivity Tests; Models, Molecular; Mutation; Neuraminidase; Oseltamivir; Protein Conformation; Reassortant Viruses; Viral Proteins; Zanamivir | 2020 |
Intravenous Zanamivir: A Viable Option for Critically Ill Patients With Influenza.
Topics: Antiviral Agents; Critical Illness; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2021 |
Baloxavir treatment of oseltamivir-resistant influenza A/H1pdm09 in two immunocompromised patients.
Topics: Alphainfluenzavirus; Antiviral Agents; Dibenzothiepins; Drug Resistance, Viral; Humans; Immunocompromised Host; Influenza, Human; Morpholines; Neuraminidase; Oseltamivir; Pyridones; Triazines; Zanamivir | 2021 |
Low rate of oseltamivir prescription among adults and children with confirmed influenza illness in France during the 2018-19 influenza season.
Topics: Adult; Antiviral Agents; Child; Enzyme Inhibitors; Female; France; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pregnancy; Prescriptions; Prospective Studies; Seasons; Zanamivir | 2021 |
Design of Neuraminidase-Targeted Imaging and Therapeutic Agents for the Diagnosis and Treatment of Influenza Virus Infections.
Topics: Animals; Enzyme Inhibitors; HEK293 Cells; Humans; Influenza A virus; Influenza, Human; Mice; Neuraminidase; Optical Imaging; Orthomyxoviridae Infections; Viral Proteins; Zanamivir | 2021 |
The safety and efficacy of the long-acting neuraminidase inhibitor laninamivir octanoate hydrate for Inhalation Suspension Set in children under the age of 5 in a post-marketing surveillance.
Topics: Administration, Inhalation; Antiviral Agents; Child, Preschool; Guanidines; Humans; Influenza, Human; Neuraminidase; Product Surveillance, Postmarketing; Pyrans; Sialic Acids; Zanamivir | 2021 |
Adverse events of prophylactic anti-influenza agents in medical staffs.
Topics: Adult; Antiviral Agents; Drug-Related Side Effects and Adverse Reactions; Humans; Influenza, Human; Medical Staff; Middle Aged; Oseltamivir; Post-Exposure Prophylaxis; Retrospective Studies; Zanamivir | 2017 |
Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2015-2016.
Topics: Acids, Carbocyclic; Amino Acid Substitution; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Enzyme Inhibitors; Epidemiological Monitoring; Global Health; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza B virus; Influenza, Human; Inhibitory Concentration 50; Microbial Sensitivity Tests; Neuraminidase; Oseltamivir; Pyrans; Seasons; Sialic Acids; World Health Organization; Zanamivir | 2017 |
Influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza annual report, 2015.
Topics: Africa; Annual Reports as Topic; Antigens, Viral; Antiviral Agents; Asia; Australia; Drug Resistance, Viral; Genotype; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza Vaccines; Influenza, Human; Oseltamivir; Phylogeny; World Health Organization; Zanamivir | 2017 |
Drug Susceptibility Evaluation of an Influenza A(H7N9) Virus by Analyzing Recombinant Neuraminidase Proteins.
Topics: Acids, Carbocyclic; Antiviral Agents; Cyclopentanes; Databases, Genetic; Drug Resistance, Multiple, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H7N9 Subtype; Influenza, Human; Inhibitory Concentration 50; Neuraminidase; Oseltamivir; Protein Conformation; Pyrans; Recombinant Proteins; Sialic Acids; Viral Proteins; Zanamivir | 2017 |
Screening for Neuraminidase Inhibitor Resistance Markers among Avian Influenza Viruses of the N4, N5, N6, and N8 Neuraminidase Subtypes.
Topics: Acids, Carbocyclic; Amino Acid Substitution; Animals; Antiviral Agents; Birds; Cyclopentanes; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza in Birds; Influenza, Human; Madin Darby Canine Kidney Cells; Mutagenesis; Neuraminidase; Orthomyxoviridae; Oseltamivir; Reverse Genetics; Zanamivir | 2018 |
The additive effect of clarithromycin on influenza A infection in the elderly patients and patients with comorbid diseases.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antiviral Agents; Clarithromycin; Cohort Studies; Comorbidity; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Influenza A virus; Influenza, Human; Male; Middle Aged; Neuraminidase; Oseltamivir; Phosphorous Acids; Pneumonia; Prospective Studies; Treatment Outcome; Zanamivir | 2017 |
Oseltamivir Treatment of Influenza in Children.
Topics: Child; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Randomized Controlled Trials as Topic; Zanamivir | 2018 |
Antiviral resistance due to deletion in the neuraminidase gene and defective interfering-like viral polymerase basic 2 RNA of influenza A virus subtype H3N2.
Topics: Animals; Antiviral Agents; Defective Viruses; Denmark; Dogs; Drug Resistance, Viral; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Madin Darby Canine Kidney Cells; Neuraminidase; Oseltamivir; Respiratory System; RNA-Dependent RNA Polymerase; RNA, Viral; Sequence Deletion; Treatment Outcome; Viral Proteins; Zanamivir | 2018 |
A Sulfonozanamivir Analogue Has Potent Anti-influenza Virus Activity.
Topics: Antiviral Agents; Arylsulfonates; Catalytic Domain; Crystallography, X-Ray; Humans; Influenza A virus; Influenza, Human; Molecular Docking Simulation; Neuraminidase; Virus Replication; Zanamivir | 2018 |
Clinical effectiveness of four neuraminidase inhibitors (oseltamivir, zanamivir, laninamivir, and peramivir) for children with influenza A and B in the 2014-2015 to 2016-2017 influenza seasons in Japan.
Topics: Acids, Carbocyclic; Adolescent; Betainfluenzavirus; Child; Child, Preschool; Cyclopentanes; Enzyme Inhibitors; Female; Guanidines; Humans; Infant; Infant, Newborn; Influenza A virus; Influenza, Human; Japan; Male; Neuraminidase; Oseltamivir; Pyrans; Seasons; Sialic Acids; Treatment Outcome; Zanamivir | 2018 |
Trends of neuraminidase inhibitors use in children with influenza related respiratory infections.
Topics: Acids, Carbocyclic; Antiviral Agents; Child; Child, Preschool; Cyclopentanes; Drug Utilization; Enzyme Inhibitors; Female; Guanidines; Hospitalization; Humans; Infant; Influenza, Human; Japan; Male; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2018 |
Clinicians' attitude towards a placebo-controlled randomised clinical trial investigating the effect of neuraminidase inhibitors in adults hospitalised with influenza.
Topics: Adult; Antiviral Agents; Attitude of Health Personnel; Glycoside Hydrolase Inhibitors; Hospitalization; Humans; Influenza, Human; Medical Staff, Hospital; Neuraminidase; Oseltamivir; Randomized Controlled Trials as Topic; Research Personnel; Surveys and Questionnaires; United Kingdom; Zanamivir | 2018 |
Triple combination of FDA-approved drugs including flufenamic acid, clarithromycin and zanamivir improves survival of severe influenza in mice.
Topics: Animals; Antiviral Agents; Clarithromycin; Drug Approval; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Flufenamic Acid; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Interleukin-1beta; Lung; Mice; Mice, Inbred BALB C; Tumor Necrosis Factor-alpha; United States; United States Food and Drug Administration; Zanamivir | 2018 |
Duration of fever and other symptoms after the inhalation of laninamivir octanoate hydrate in the 2016/17 Japanese influenza season; comparison with the 2011/12 to 2015/16 seasons.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Female; Fever; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Inhibitory Concentration 50; Male; Middle Aged; Pyrans; Seasons; Sialic Acids; Young Adult; Zanamivir | 2018 |
Humoral immunity to influenza in an at-risk population and severe influenza cases in Russia in 2016-2017.
Topics: Animals; Antibodies, Viral; Antiviral Agents; Birds; Epidemics; Humans; Immunity, Herd; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Influenza A Virus, H5N8 Subtype; Influenza B virus; Influenza in Birds; Influenza, Human; Oseltamivir; Poultry; Poultry Diseases; Russia; Zanamivir | 2018 |
Antigenic and genetic characterization of influenza viruses isolated in Mozambique during the 2015 season.
Topics: Animals; Antiviral Agents; Child; Child, Preschool; Dogs; Female; Hemagglutination Inhibition Tests; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Infant; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Madin Darby Canine Kidney Cells; Male; Mozambique; Neuraminidase; Oseltamivir; Phylogeny; Viral Proteins; Zanamivir | 2018 |
Outpatient influenza antivirals in a distributed data network for influenza surveillance.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Drug Utilization; Epidemiological Monitoring; Female; Humans; Infant; Infant, Newborn; Influenza, Human; Male; Middle Aged; Oseltamivir; Outpatients; Prescriptions; Young Adult; Zanamivir | 2018 |
Characteristics and mortality of severe influenza cases treated with parenteral aqueous zanamivir, United Kingdom, October 2009 to January 2011.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Child; Child, Preschool; Female; Hospitalization; Humans; Infant; Infant, Newborn; Influenza, Human; Infusions, Parenteral; Male; Middle Aged; Pandemics; Retrospective Studies; Treatment Outcome; United Kingdom; Young Adult; Zanamivir | 2019 |
Clinical management and viral genomic diversity analysis of a child's influenza A(H1N1)pdm09 infection in the context of a severe combined immunodeficiency.
Topics: Antiviral Agents; Child; Cord Blood Stem Cell Transplantation; Drug Resistance, Viral; Genetic Variation; Humans; Immunoglobulins, Intravenous; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation, Missense; Neuraminidase; Oseltamivir; Real-Time Polymerase Chain Reaction; Severe Combined Immunodeficiency; Viral Load; Viral Proteins; Zanamivir | 2018 |
Intravenous zanamivir for influenza myocarditis and enteral malabsorption.
Topics: Administration, Intravenous; Adult; Antiviral Agents; Catecholamines; Female; Humans; Influenza, Human; Malabsorption Syndromes; Middle Aged; Myocarditis; Oseltamivir; Zanamivir | 2018 |
Comparison of the Clinical Courses of Patients with Influenza after Neuraminidase Inhibitors Treatment: A Postcard Survey of the 2013-2014 Influenza Season in Osaka.
Topics: Acids, Carbocyclic; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Cyclopentanes; Disease Outbreaks; Enzyme Inhibitors; Female; Guanidines; Humans; Infant; Influenza, Human; Japan; Male; Middle Aged; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Surveys and Questionnaires; Treatment Outcome; Zanamivir | 2016 |
Mobility-Based Quantification of Multivalent Virus-Receptor Interactions: New Insights Into Influenza A Virus Binding Mode.
Topics: Cell Membrane; G(M1) Ganglioside; Hemagglutinins; Humans; Influenza A virus; Influenza, Human; Lipid Bilayers; Neuraminidase; Receptors, Virus; Zanamivir | 2019 |
Association of severe abnormal behavior and acetaminophen with/without neuraminidase inhibitors.
Topics: Acetaminophen; Adolescent; Age Factors; Antiviral Agents; Behavioral Symptoms; Child; Drug Therapy, Combination; Enzyme Inhibitors; Female; Guanidines; Humans; Incidence; Influenza, Human; Japan; Male; Neuraminidase; Oseltamivir; Pyrans; Risk Factors; Sialic Acids; Zanamivir | 2019 |
Antiviral treatment and virological monitoring of oseltamivir-resistant influenza virus A(H1N1)pdm09 in a patient with chronic B lymphocytic leukemia.
Topics: Aged; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Leukemia, Lymphocytic, Chronic, B-Cell; Oseltamivir; Pneumonia, Viral; Treatment Outcome; Virus Shedding; Zanamivir | 2019 |
Immune-mediated Drug-induced Liver Injury Caused by Laninamivir Octanoate Hydrate.
Topics: Adolescent; Antiviral Agents; Azathioprine; Chemical and Drug Induced Liver Injury; Female; Guanidines; Hepatitis, Autoimmune; Humans; Immunosuppressive Agents; Influenza A virus; Influenza, Human; Jaundice; Pyrans; Sialic Acids; Zanamivir | 2019 |
Drug-induced pneumonitis following the administration of laninamivir octanoate: The first two reported cases.
Topics: Administration, Inhalation; Adult; Antiviral Agents; Bronchoalveolar Lavage; Female; Glucocorticoids; Guanidines; Humans; Influenza A virus; Influenza, Human; Lung; Neuraminidase; Pneumonia; Pyrans; Respiration, Artificial; Sialic Acids; Tomography, X-Ray Computed; Treatment Outcome; Viral Proteins; Young Adult; Zanamivir | 2019 |
Report on influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza in 2017
Topics: Animals; Antigens, Viral; Antiviral Agents; Australia; Chickens; Dogs; Drug Resistance, Viral; Eggs; Female; Humans; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Madin Darby Canine Kidney Cells; Neuraminidase; Oseltamivir; Phylogeny; World Health Organization; Zanamivir | 2019 |
Highly pathogenic avian influenza H7N9 viruses with reduced susceptibility to neuraminidase inhibitors showed comparable replication capacity to their sensitive counterparts.
Topics: Amino Acid Substitution; Animals; Antiviral Agents; Chickens; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H7N9 Subtype; Influenza in Birds; Influenza, Human; Madin Darby Canine Kidney Cells; Neuraminidase; Oseltamivir; Virus Replication; Zanamivir | 2019 |
Mutations at the monomer-monomer interface away from the active site of influenza B virus neuraminidase reduces susceptibility to neuraminidase inhibitor drugs.
Topics: Animals; Antiviral Agents; Catalytic Domain; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza B virus; Influenza, Human; Japan; Madin Darby Canine Kidney Cells; Models, Molecular; Mutation; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Viral Proteins; Zanamivir | 2013 |
Population pharmacokinetics of laninamivir and its prodrug laninamivir octanoate in healthy subjects and in adult and pediatric patients with influenza virus infection.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza, Human; Male; Middle Aged; Neuraminidase; Prodrugs; Pyrans; Sialic Acids; Zanamivir | 2013 |
Neuraminidase inhibitor susceptibility surveillance of influenza viruses circulating worldwide during the 2011 Southern Hemisphere season.
Topics: Acids, Carbocyclic; Africa; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Enzyme Inhibitors; Global Health; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Neuraminidase; Oceania; Oseltamivir; Pyrans; Seasons; Sentinel Surveillance; Sialic Acids; South America; Zanamivir | 2013 |
Outcomes of infants exposed to oseltamivir or zanamivir in utero during pandemic (H1N1) 2009.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Antiviral Agents; Female; Humans; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Pandemics; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prospective Studies; Time Factors; Zanamivir | 2013 |
Permeability enhancers dramatically increase zanamivir absolute bioavailability in rats: implications for an orally bioavailable influenza treatment.
Topics: Absorption; Administration, Oral; Animals; Biological Availability; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Enzyme Inhibitors; Humans; Influenza, Human; Male; Neuraminidase; Orthomyxoviridae Infections; Rats; Rats, Sprague-Dawley; Time Factors; Zanamivir | 2013 |
Value of pharmacy-based influenza surveillance - Ontario, Canada, 2009.
Topics: Adolescent; Adult; Antiviral Agents; Drug Prescriptions; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Ontario; Oseltamivir; Population Surveillance; Reproducibility of Results; Retrospective Studies; Time Factors; Young Adult; Zanamivir | 2013 |
Early therapy with neuraminidase inhibitors for influenza A (H1N1) pdm 2009 infection.
Topics: Child; Early Medical Intervention; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Zanamivir | 2013 |
Neuraminidase inhibitor susceptibility profile of pandemic and seasonal influenza viruses during the 2009-2010 and 2010-2011 influenza seasons in Japan.
Topics: Acids, Carbocyclic; Adult; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Japan; Microbial Sensitivity Tests; Neuraminidase; Pandemics; Pyrans; Seasons; Sialic Acids; Viral Proteins; Zanamivir | 2013 |
Resistance to neuraminidase inhibitors conferred by an R292K mutation in a human influenza virus H7N9 isolate can be masked by a mixed R/K viral population.
Topics: Acids, Carbocyclic; Amino Acid Substitution; Antiviral Agents; China; Coinfection; Cyclopentanes; Drug Resistance, Viral; Guanidines; Humans; Influenza A Virus, H7N9 Subtype; Influenza, Human; Microbial Sensitivity Tests; Mutation, Missense; Neuraminidase; Oseltamivir; Viral Plaque Assay; Viral Proteins; Zanamivir | 2013 |
Bioluminescence-based neuraminidase inhibition assay for monitoring influenza virus drug susceptibility in clinical specimens.
Topics: Antiviral Agents; Drug Resistance, Viral; Enzyme Assays; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Kinetics; Luminescent Measurements; Microbial Sensitivity Tests; Neuraminidase; Oseltamivir; Protein Binding; Viral Proteins; Zanamivir | 2013 |
Should neuraminidase inhibitors be prescribed for patients with influenza?
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2014 |
Comparison of the clinical effectiveness of zanamivir and laninamivir octanoate for children with influenza A(H3N2) and B in the 2011-2012 season.
Topics: Adolescent; Antiviral Agents; Child; Child, Preschool; Chromatography, Affinity; Female; Fever; Guanidines; Humans; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Male; Prospective Studies; Pyrans; Sialic Acids; Time Factors; Treatment Outcome; Zanamivir | 2014 |
Efficacy of a single intravenous administration of laninamivir (an active metabolite of laninamivir octanoate) in an influenza virus infection mouse model.
Topics: Administration, Intravenous; Animals; Antiviral Agents; Disease Models, Animal; Female; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza B virus; Influenza, Human; Mice; Mice, Inbred BALB C; Pyrans; Sialic Acids; Zanamivir | 2013 |
Therapy of H7N9 pneumonia: current perspectives.
Topics: Acids, Carbocyclic; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Guanidines; Humans; Influenza A Virus, H7N9 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Pulmonary Ventilation; Zanamivir | 2013 |
Anti-influenza activity of Alchemilla mollis extract: possible virucidal activity against influenza virus particles.
Topics: Alchemilla; Animals; Antiviral Agents; Chickens; Dogs; Drug Synergism; Erythrocytes; Hemagglutination Inhibition Tests; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N2 Subtype; Influenza, Human; Madin Darby Canine Kidney Cells; Medicine, Traditional; Orthomyxoviridae; Plant Extracts; Virus Replication; Zanamivir | 2013 |
Neuraminidase inhibitors for critically ill children with influenza.
Topics: Acids, Carbocyclic; Adolescent; Betainfluenzavirus; California; Child; Child, Preschool; Critical Care; Critical Illness; Cyclopentanes; Drug Administration Schedule; Enzyme Inhibitors; Guanidines; Hospitalization; Humans; Infant; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza, Human; Logistic Models; Multivariate Analysis; Neuraminidase; Odds Ratio; Oseltamivir; Pandemics; Population Surveillance; Treatment Outcome; Zanamivir | 2013 |
Effectiveness of neuraminidase inhibitors in preventing hospitalization during the H1N1 influenza pandemic in British Columbia, Canada.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; British Columbia; Child; Child, Preschool; Cohort Studies; Female; Hospitalization; Humans; Infant; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Neuraminidase; Oseltamivir; Retrospective Studies; Treatment Outcome; Young Adult; Zanamivir | 2014 |
Computational assay of H7N9 influenza neuraminidase reveals R292K mutation reduces drug binding affinity.
Topics: Acids, Carbocyclic; Antiviral Agents; Computational Biology; Cyclopentanes; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H7N9 Subtype; Influenza, Human; Molecular Dynamics Simulation; Mutation; Neuraminidase; Oseltamivir; Protein Binding; Zanamivir | 2013 |
Sequential influenza B viral load and susceptibility in children treated with oseltamivir and zanamivir.
Topics: Antiviral Agents; Child; Child, Preschool; Female; Humans; Infant; Influenza B virus; Influenza, Human; Microbial Sensitivity Tests; Nasal Cavity; Oseltamivir; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Viral Load; Zanamivir | 2014 |
Critics attack chief medical officer's advice to use antivirals for flu.
Topics: Antiviral Agents; Evidence-Based Medicine; Humans; Influenza, Human; Oseltamivir; Practice Guidelines as Topic; State Medicine; United Kingdom; Zanamivir | 2014 |
Department of Health's misguided alert recommending neuraminidase inhibitors for flu.
Topics: England; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Practice Guidelines as Topic; Zanamivir | 2014 |
Pregnancy outcome following maternal use of zanamivir or oseltamivir during the 2009 influenza A/H1N1 pandemic: a national prospective surveillance study.
Topics: Adolescent; Adult; Antiviral Agents; Epidemiological Monitoring; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Middle Aged; Oseltamivir; Pandemics; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prospective Studies; United Kingdom; Young Adult; Zanamivir | 2014 |
Study claiming Tamiflu saved lives was based on "flawed" analysis.
Topics: Antiviral Agents; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pandemics; Zanamivir | 2014 |
Severe influenza A H7N9 pneumonia with rapid virological response to intravenous zanamivir.
Topics: Adult; Antiviral Agents; Female; Humans; Influenza A Virus, H7N9 Subtype; Influenza, Human; Pneumonia, Viral; Respiration Disorders; Time Factors; Treatment Outcome; Zanamivir | 2014 |
Effects of vaccination and the new neuraminidase inhibitor, laninamivir, on influenza infection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Female; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Japan; Male; Middle Aged; Neuraminidase; Orthomyxoviridae; Pyrans; Sialic Acids; Vaccination; Young Adult; Zanamivir | 2014 |
Cochrane review questions effectiveness of neuraminidase inhibitors.
Topics: Antiviral Agents; Humans; Influenza, Human; Oseltamivir; Zanamivir | 2014 |
Multisystem failure: the story of anti-influenza drugs.
Topics: Antiviral Agents; Drug and Narcotic Control; Evidence-Based Medicine; History, 20th Century; History, 21st Century; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pandemics; Policy Making; Zanamivir | 2014 |
Peramivir and laninamivir susceptibility of circulating influenza A and B viruses.
Topics: Acids, Carbocyclic; Africa; Antiviral Agents; Asia; Cyclopentanes; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Japan; Microbial Sensitivity Tests; Mutation, Missense; Neuraminidase; Oceania; Pyrans; Sialic Acids; Viral Proteins; Zanamivir | 2014 |
Tamiflu report comes under fire.
Topics: Antiviral Agents; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Neuraminidase; Observational Studies as Topic; Oseltamivir; Randomized Controlled Trials as Topic; Strategic Stockpile; Zanamivir | 2014 |
Editor in chief's reply to Nguyen-Van-Tam.
Topics: Antiviral Agents; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pandemics; Zanamivir | 2014 |
Principal author of PRIDE study responds to news story in The BMJ claiming that the study was based on "flawed" analysis.
Topics: Antiviral Agents; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pandemics; Zanamivir | 2014 |
Authors' reply to Mark Jones's second critique of the study by Muthuri and colleagues reported in The BMJ.
Topics: Antiviral Agents; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pandemics; Zanamivir | 2014 |
Authors' reply to Mark Jones's critique of the study by Muthuri and colleagues reported in The BMJ.
Topics: Antiviral Agents; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pandemics; Zanamivir | 2014 |
Mark Jones's reply to Myles and Leonardi-Bee's response to his critique of their paper reported in The BMJ.
Topics: Antiviral Agents; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pandemics; Zanamivir | 2014 |
Tug of war for antiviral drugs data.
Topics: Antiviral Agents; Clinical Trials as Topic; Dissent and Disputes; Drug Industry; Humans; Influenza, Human; Information Dissemination; Oseltamivir; Research Design; Zanamivir | 2014 |
Neuraminidase inhibitors for influenza.
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Risk Assessment; Zanamivir | 2014 |
Effectiveness of neuraminidase inhibitors for severe influenza.
Topics: Antiviral Agents; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pandemics; Zanamivir | 2014 |
Comparison between virus shedding and fever duration after treating children with pandemic A H1N1/09 and children with A H3N2 with a neuraminidase inhibitor.
Topics: Acids, Carbocyclic; Antiviral Agents; Child; Child, Preschool; Cyclopentanes; Enzyme Inhibitors; Female; Fever; Guanidines; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pyrans; Severity of Illness Index; Sialic Acids; Time Factors; Treatment Outcome; Viral Proteins; Virus Shedding; Zanamivir | 2015 |
Antivirals for influenza: where now for clinical practice and pandemic preparedness?
Topics: Antiviral Agents; Child; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pandemics; Zanamivir | 2014 |
Was the flu drug zanamivir a breakthrough or money for old rope?
Topics: Antiviral Agents; Drug Approval; Drugs, Investigational; Enzyme Inhibitors; Humans; Influenza, Human; United States; United States Food and Drug Administration; Zanamivir | 2014 |
Anti-viral drugs in flu: not that good?
Topics: Adult; Antiviral Agents; Child, Preschool; Humans; Influenza, Human; Oseltamivir; Treatment Outcome; Zanamivir | 2014 |
Predictors of fatality in pandemic influenza A (H1N1) virus infection among adults.
Topics: Adult; Antiviral Agents; Cross Infection; Disease Outbreaks; Female; Hospitalization; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Multivariate Analysis; Neuraminidase; Odds Ratio; Oseltamivir; Pregnancy; Turkey; Zanamivir | 2014 |
Primarily oseltamivir-resistant influenza A (H1N1pdm09) virus evolving into a multidrug-resistant virus carrying H275Y and I223R neuraminidase substitutions.
Topics: Amino Acid Substitution; Antiviral Agents; Drug Resistance, Multiple, Viral; Evolution, Molecular; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Middle Aged; Mutation; Myelodysplastic Syndromes; Neuraminidase; Oseltamivir; Viral Proteins; Zanamivir | 2015 |
Statistical and methodological concerns about the beneficial effect of neuraminidase inhibitors on mortality.
Topics: Antiviral Agents; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pandemics; Zanamivir | 2014 |
Statistical and methodological concerns about the beneficial effect of neuraminidase inhibitors on mortality.
Topics: Antiviral Agents; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pandemics; Zanamivir | 2014 |
Statistical and methodological concerns about the beneficial effect of neuraminidase inhibitors on mortality.
Topics: Antiviral Agents; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pandemics; Zanamivir | 2014 |
Statistical and methodological concerns about the beneficial effect of neuraminidase inhibitors on mortality.
Topics: Antiviral Agents; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pandemics; Zanamivir | 2014 |
Oseltamivir and zanamivir have limited effect on symptoms and do not reduce hospitalisation or serious complications of influenza.
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2014 |
Neuraminidase-producing oral mitis group streptococci potentially contribute to influenza viral infection and reduction in antiviral efficacy of zanamivir.
Topics: Analysis of Variance; Antiviral Agents; Blotting, Western; Fluorescent Antibody Technique, Indirect; Humans; Influenza, Human; Neuraminidase; Streptococcus mitis; Streptococcus oralis; Zanamivir | 2015 |
Glycan based detection and drug susceptibility of influenza virus.
Topics: Antiviral Agents; Biosensing Techniques; Drug Resistance, Viral; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Limit of Detection; Microarray Analysis; Microbial Sensitivity Tests; Oseltamivir; Polysaccharides; Zanamivir | 2014 |
Y155H amino acid substitution in influenza A(H1N1)pdm09 viruses does not confer a phenotype of reduced susceptibility to neuraminidase inhibitors.
Topics: Amino Acid Substitution; Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Female; Humans; Immunoenzyme Techniques; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Microbial Sensitivity Tests; Neuraminidase; Oseltamivir; Pandemics; Phenotype; RNA, Viral; Seasons; Sequence Analysis, DNA; Spain; Viral Proteins; Zanamivir | 2014 |
Influenza A(H1N1)pdm09 resistance and cross-decreased susceptibility to oseltamivir and zanamivir antiviral drugs.
Topics: Adult; Antiviral Agents; Drug Resistance, Viral; Female; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza, Human; Inhibitory Concentration 50; Male; Middle Aged; Mutation, Missense; Neuraminidase; Oseltamivir; Portugal; Viral Proteins; Zanamivir | 2015 |
Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2012-2013.
Topics: Acids, Carbocyclic; Amino Acid Substitution; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2014 |
Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children.
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2014 |
Pregnancy outcomes of women exposed to laninamivir during pregnancy.
Topics: Adolescent; Adult; Antiviral Agents; Female; Guanidines; Humans; Infant, Newborn; Influenza, Human; Japan; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Pyrans; Retrospective Studies; Sialic Acids; Young Adult; Zanamivir | 2014 |
Development of 3D-QSAR combination approach for discovering and analysing neuraminidase inhibitors in silico.
Topics: Algorithms; Binding Sites; Computational Biology; Drug Design; Humans; Influenza, Human; Inhibitory Concentration 50; Least-Squares Analysis; Models, Molecular; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Quantitative Structure-Activity Relationship; Software; Technology, Pharmaceutical; Zanamivir | 2014 |
Zanamivir for influenza in adults and children shows limited benefit for treatment of symptomatic influenza and no effect on relevant complications.
Topics: Antiviral Agents; Humans; Influenza, Human; Zanamivir | 2015 |
Multiple influenza A (H3N2) mutations conferring resistance to neuraminidase inhibitors in a bone marrow transplant recipient.
Topics: Acids, Carbocyclic; Adult; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Enzyme Inhibitors; Fatal Outcome; Female; Guanidines; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Immunosuppressive Agents; Influenza A Virus, H3N2 Subtype; Influenza, Human; Leukemia, B-Cell; Models, Molecular; Mutation; Neuraminidase; Oseltamivir; Transplantation, Homologous; Viral Proteins; Zanamivir | 2014 |
[Drug susceptibility of wild-type and mutant H7N9 neuraminidase to zanamivir and oseltamivir].
Topics: Antiviral Agents; Humans; Influenza A Virus, H7N9 Subtype; Influenza, Human; Microbial Sensitivity Tests; Mutation; Neuraminidase; Oseltamivir; Viral Proteins; Zanamivir | 2014 |
In vitro neuraminidase inhibitory activity of four neuraminidase inhibitors against clinical isolates of influenza virus in the Japanese 2012-2013 season.
Topics: Acids, Carbocyclic; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antiviral Agents; Child; Child, Preschool; Cyclopentanes; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Infant; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Inhibitory Concentration 50; Japan; Madin Darby Canine Kidney Cells; Middle Aged; Neuraminidase; Oseltamivir; Young Adult; Zanamivir | 2015 |
Characterization of human Influenza Viruses in Lebanon during 2010-2011 and 2011-2012 post-pandemic seasons.
Topics: Acids, Carbocyclic; Amantadine; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Lebanon; Microbial Sensitivity Tests; Mutation; Neuraminidase; Oseltamivir; Pandemics; Phylogeny; Pyrans; Sialic Acids; Zanamivir | 2014 |
Organocatalytic and scalable synthesis of the anti-influenza drugs zanamivir, laninamivir, and CS-8958.
Topics: Antiviral Agents; Catalysis; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 2014 |
Review: Neuraminidase inhibitors reduce symptomatic influenza; oseltamivir does not reduce hospitalizations.
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2014 |
Do we need a replacement medication for influenza with good efficacy?
Topics: Antiviral Agents; Drug Combinations; Drug Synergism; Humans; Indoles; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Plant Extracts; Treatment Outcome; Zanamivir | 2014 |
Neuraminidase inhibitors, superinfection and corticosteroids affect survival of influenza patients.
Topics: Acids, Carbocyclic; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Beijing; Cohort Studies; Cyclopentanes; Enzyme Inhibitors; Female; Guanidines; Hong Kong; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Influenza, Human; Male; Middle Aged; Multivariate Analysis; Neuraminidase; Oseltamivir; Pneumonia, Bacterial; Proportional Hazards Models; Prospective Studies; Protective Factors; Respiratory Insufficiency; Retrospective Studies; Risk Factors; Singapore; Superinfection; Young Adult; Zanamivir | 2015 |
A surface plasmon resonance assay for measurement of neuraminidase inhibition, sensitivity of wild-type influenza neuraminidase and its H274Y mutant to the antiviral drugs zanamivir and oseltamivir.
Topics: Animals; Antiviral Agents; Cell Line; Enzyme Inhibitors; Humans; Influenza, Human; Inhibitory Concentration 50; Insecta; Mutation; Neuraminidase; Oseltamivir; Surface Plasmon Resonance; Zanamivir | 2015 |
Emergence of Multidrug-Resistant Influenza A(H1N1)pdm09 Virus Variants in an Immunocompromised Child Treated With Oseltamivir and Zanamivir.
Topics: Acids, Carbocyclic; Amino Acid Substitution; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Immunocompromised Host; Infant; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Mutation, Missense; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Viral Proteins; Zanamivir | 2015 |
E119D Neuraminidase Mutation Conferring Pan-Resistance to Neuraminidase Inhibitors in an A(H1N1)pdm09 Isolate From a Stem-Cell Transplant Recipient.
Topics: Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Mutation; Nasal Cavity; Neuraminidase; Stem Cell Transplantation; Zanamivir | 2015 |
Quantitative analysis of influenza A (H3N2) E119V and R292K variants in clinical specimens by real-time reverse transcription polymerase chain reaction.
Topics: Amino Acid Substitution; Antiviral Agents; Bodily Secretions; Child; Child, Preschool; Drug Resistance, Viral; Female; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Male; Microbial Sensitivity Tests; Molecular Sequence Data; Mutant Proteins; Mutation, Missense; Nasal Cavity; Oseltamivir; Real-Time Polymerase Chain Reaction; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Zanamivir | 2015 |
In vitro neuraminidase inhibitory activity of four neuraminidase inhibitors against clinical isolates of the influenza virus circulating in the Japanese 2013-2014 season.
Topics: Acids, Carbocyclic; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cyclopentanes; Enzyme Inhibitors; Female; Guanidines; Humans; Infant; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Inhibitory Concentration 50; Japan; Male; Middle Aged; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Time Factors; Young Adult; Zanamivir | 2015 |
Outcomes and Susceptibility to Neuraminidase Inhibitors in Individuals Infected With Different Influenza B Lineages: The Influenza Resistance Information Study.
Topics: Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Drug Resistance, Viral; Humans; Infant; Influenza B virus; Influenza, Human; Middle Aged; Neuraminidase; Oseltamivir; Young Adult; Zanamivir | 2016 |
WHO Global Influenza Surveillance and Response System working group on surveillance of influenza antiviral susceptibility.
Topics: Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Global Health; Humans; Influenza A Virus, H10N7 Subtype; Influenza, Human; Microbial Sensitivity Tests; Neuraminidase; Oseltamivir; Polymorphism, Single Nucleotide; Population Surveillance; Practice Guidelines as Topic; World Health Organization; Zanamivir | 2015 |
[Susceptibility of human influenza A (H3N2) viruses to neuraminidase inhibitors isolated during 2011-2012 in China].
Topics: Antiviral Agents; China; Drug Resistance, Viral; Enzyme Inhibitors; Epidemiological Monitoring; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2015 |
Knowledge gaps about Tamiflu and Relenza for pandemic flu are blamed on research failure.
Topics: Antiviral Agents; Biomedical Research; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Pandemics; Zanamivir | 2015 |
Influenza A H1N1 pdm09-associated myocarditis during zanamivir therapy.
Topics: Antiviral Agents; Child; DNA, Viral; Echocardiography; Electrocardiography; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Myocarditis; Zanamivir | 2015 |
[Haut Conseil de la Santé Publique (HCSP). Guidance on the prioritization of antiviral drugs in case of seasonal influenza epidemics (March 3, 2015)].
Topics: Adult; Age Factors; Aged; Antiviral Agents; Child; Comorbidity; Disease Management; Disease Susceptibility; Drug Utilization; Epidemics; Female; France; Humans; Influenza Vaccines; Influenza, Human; Male; Meta-Analysis as Topic; Oseltamivir; Pregnancy; Pregnancy Complications, Infectious; Seasons; Vulnerable Populations; Zanamivir | 2015 |
Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets.
Topics: Animals; Antiviral Agents; Drug Resistance, Viral; Ferrets; Gene Deletion; Genetic Fitness; Guanidines; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Mutation; Neuraminidase; Orthomyxoviridae Infections; Pyrans; RNA, Viral; Sialic Acids; Virus Replication; Zanamivir | 2016 |
Zanamivir-resistant influenza viruses with Q136K or Q136R neuraminidase residue mutations can arise during MDCK cell culture creating challenges for antiviral susceptibility monitoring.
Topics: Animals; Antiviral Agents; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Neuraminidase; Reverse Transcriptase Polymerase Chain Reaction; Viral Proteins; Zanamivir | 2015 |
The accuracy and timeliness of neuraminidase inhibitor dispensing data for predicting laboratory-confirmed influenza.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Drug Utilization; Epidemiological Monitoring; Female; Humans; Infant; Infant, Newborn; Influenza, Human; Male; Middle Aged; Oseltamivir; Quebec; Young Adult; Zanamivir | 2016 |
Relenza-Induced Acute Myopia Change.
Topics: Acute Disease; Antiviral Agents; Female; Glucocorticoids; Histamine Antagonists; Humans; Influenza, Human; Middle Aged; Myopia; Refraction, Ocular; Zanamivir | 2016 |
NAIplot: An opensource web tool to visualize neuraminidase inhibitor (NAI) phenotypic susceptibility results using kernel density plots.
Topics: Antiviral Agents; Computer Graphics; Enzyme Assays; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza B virus; Influenza, Human; Inhibitory Concentration 50; Internet; Microbial Sensitivity Tests; Neuraminidase; Oseltamivir; Zanamivir | 2016 |
[Evidence under scrutiny. Neuraminidase inhibitors in severe influenza: yes or no?].
Topics: Ambulatory Care; Antiviral Agents; Cause of Death; Evidence-Based Medicine; Germany; Hospitalization; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Survival Analysis; Zanamivir | 2015 |
Influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza annual report, 2014.
Topics: Animals; Antigens, Viral; Antiviral Agents; Australia; Chickens; Drug Resistance, Viral; Epidemiological Monitoring; Hemagglutinins, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza Vaccines; Influenza, Human; International Cooperation; Oseltamivir; Phylogeny; Retrospective Studies; Zanamivir; Zygote | 2015 |
Influenza Virus Shedding in Laninamivir-Treated Children upon Returning to School.
Topics: Antiviral Agents; Child; Demography; Female; Guanidines; Health; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Male; Neuraminidase; Pyrans; RNA, Viral; Schools; Sialic Acids; Virus Shedding; Zanamivir | 2016 |
ECDC expert opinion on efficacy and effectiveness of neuraminidase inhibitors published for public consultation.
Topics: Antiviral Agents; Clinical Trials as Topic; Enzyme Inhibitors; European Union; Expert Testimony; Health Policy; Humans; Influenza, Human; Meta-Analysis as Topic; Neuraminidase; Treatment Outcome; Zanamivir | 2016 |
Clinical Pearls.
Topics: Acute Disease; Antiviral Agents; Humans; Influenza, Human; Myopia; Retina; Retinal Diseases; Tissue Adhesions; Vitreous Body; Vitreous Detachment; Zanamivir | 2016 |
Within-Host Models of High and Low Pathogenic Influenza Virus Infections: The Role of Macrophages.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Viral; Antiviral Agents; B-Lymphocytes; Cell Death; Epithelial Cells; Host-Pathogen Interactions; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza, Human; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Models, Immunological; Orthomyxoviridae; Orthomyxoviridae Infections; Oseltamivir; Viral Load; Virulence; Zanamivir | 2016 |
[Comparison of the clinical effectiveness of three neuraminidase inhibitors for Japanese pediatric patients with influenza in the 2013/2014 season].
Topics: Antiviral Agents; Child; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Japan; Medication Adherence; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Time Factors; Zanamivir | 2015 |
In vitro neuraminidase inhibitory concentration (IC50) of four neuraminidase inhibitors against clinical isolates of the influenza viruses circulating in the 2010-2011 to 2014-2015 Japanese influenza seasons.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Drug Resistance, Viral; Enzyme Inhibitors; Female; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza B virus; Influenza, Human; Inhibitory Concentration 50; Japan; Male; Middle Aged; Neuraminidase; Product Surveillance, Postmarketing; Young Adult; Zanamivir | 2016 |
ECDC public consultation on the use of neuraminidase inhibitors.
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2016 |
Oseltamivir resistance in an influenza A (H3N2) virus isolated from an immunocompromised patient during the 2014-2015 influenza season in Alberta, Canada.
Topics: Alberta; Antiviral Agents; Drug Resistance, Viral; Humans; Immunocompromised Host; Influenza A Virus, H3N2 Subtype; Influenza, Human; Male; Middle Aged; Mutation; Nasopharynx; Neuraminidase; Oseltamivir; Seasons; Viral Load; Zanamivir | 2016 |
Duration of fever and other symptoms after the inhalation of laninamivir octanoate hydrate for influenza treatment; comparison among the four Japanese influenza seasons from 2011-2012 to 2014-2015.
Topics: Administration, Inhalation; Antiviral Agents; Child; Female; Fever; Guanidines; Humans; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Japan; Kaplan-Meier Estimate; Male; Product Surveillance, Postmarketing; Proportional Hazards Models; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2016 |
Total Synthesis of Anti-Influenza Agents Zanamivir and Zanaphosphor via Asymmetric Aza-Henry Reaction.
Topics: Antiviral Agents; Aza Compounds; Humans; Influenza, Human; Microbial Sensitivity Tests; Molecular Conformation; Orthomyxoviridae; Zanamivir | 2016 |
Recommendations for Prevention and Control of Influenza in Children, 2016-2017.
Topics: Antiviral Agents; Child; Drug Storage; Egg Hypersensitivity; Health Personnel; Hospitalization; Humans; Immunization Schedule; Infectious Disease Transmission, Patient-to-Professional; Infectious Disease Transmission, Professional-to-Patient; Influenza Vaccines; Influenza, Human; Oseltamivir; United States; Zanamivir | 2016 |
Droplet digital PCR to investigate quasi-species at codons 119 and 275 of the A(H1N1)pdm09 neuraminidase during zanamivir and oseltamivir therapies.
Topics: Antiviral Agents; Codon; Drug Resistance, Viral; Genetic Variation; Genotyping Techniques; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Neuraminidase; Oseltamivir; Polymerase Chain Reaction; Sensitivity and Specificity; Zanamivir | 2017 |
Antiviral susceptibility profile of influenza A viruses; keep an eye on immunocompromised patients under prolonged treatment.
Topics: Aged; Antiviral Agents; Drug Resistance, Viral; Female; Genotype; Greece; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Immunocompromised Host; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Inhibitory Concentration 50; Male; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Neuraminidase; Oseltamivir; Viral Proteins; Zanamivir | 2017 |
Fate of new three anti-influenza drugs and one prodrug in the water environment.
Topics: Acids, Carbocyclic; Amides; Antiviral Agents; Biodegradation, Environmental; Cyclopentanes; Environmental Monitoring; Fresh Water; Guanidines; Half-Life; Humans; Influenza, Human; Japan; Prodrugs; Pyrans; Pyrazines; Rivers; Seasons; Sewage; Sialic Acids; Water Pollutants, Chemical; Zanamivir | 2017 |
Molecular Basis for Differential Patterns of Drug Resistance in Influenza N1 and N2 Neuraminidase.
Topics: Antiviral Agents; Binding Sites; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Hydrogen Bonding; Influenza A virus; Influenza, Human; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Neuraminidase; Oseltamivir; Protein Binding; Protein Structure, Quaternary; Static Electricity; Substrate Specificity; Thermodynamics; Zanamivir | 2016 |
Development of oseltamivir and zanamivir resistance in influenza A(H1N1)pdm09 virus, Denmark, 2014.
Topics: Antiviral Agents; Denmark; Drug Resistance, Viral; Genotype; Humans; Immunocompromised Host; Influenza A Virus, H1N1 Subtype; Influenza, Human; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Mutation; Neuraminidase; Oseltamivir; Reverse Transcriptase Polymerase Chain Reaction; Treatment Outcome; Zanamivir | 2017 |
Molecular modeling and lead design of substituted zanamivir derivatives as potent anti-influenza drugs.
Topics: Antiviral Agents; Catalytic Domain; Drug Design; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Molecular Dynamics Simulation; Neuraminidase; Zanamivir | 2016 |
Stockpile, use during outbreaks, restock, repeat.
Topics: Antiviral Agents; Humans; Influenza Vaccines; Influenza, Human; Oseltamivir; Post-Exposure Prophylaxis; Strategic Stockpile; Zanamivir | 2017 |
In silico prediction of drug resistance due to S247R mutation of Influenza H1N1 neuraminidase protein.
Topics: Catalytic Domain; Computer Simulation; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Ligands; Mutation; Neuraminidase; Oseltamivir; Protein Binding; Viral Proteins; Zanamivir | 2018 |
Comparison of the clinical effectiveness of oseltamivir and zanamivir against influenza virus infection in children.
Topics: Adolescent; Antiviral Agents; Child; Child, Preschool; Fever; Humans; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Oseltamivir; Retrospective Studies; Treatment Outcome; Zanamivir | 2008 |
Editorial commentary: viral susceptibility and the choice of influenza antivirals.
Topics: Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Practice Patterns, Physicians'; Zanamivir | 2008 |
Evaluation of intravenous zanamivir against experimental influenza A (H5N1) virus infection in cynomolgus macaques.
Topics: Animals; Antiviral Agents; Disease Models, Animal; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Macaca; Male; Zanamivir | 2008 |
Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2008.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Female; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Oseltamivir; Pregnancy; Seasons; United States; Zanamivir | 2008 |
Statement on influenza vaccination for the 2008-2009 season. An Advisory Committee Statement (ACS).
Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Canada; Female; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza Vaccines; Influenza, Human; Oseltamivir; Pregnancy; Zanamivir | 2008 |
Antivirals and influenza: frequency of resistance.
Topics: Amantadine; Antiviral Agents; Disease Outbreaks; Drug Resistance, Viral; Humans; Influenza A virus; Influenza A Virus, H5N1 Subtype; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Rimantadine; Zanamivir | 2008 |
Insights into inflammation and influenza.
Topics: Animals; Antiviral Agents; Celecoxib; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Humans; Immunologic Factors; Influenza A Virus, H5N1 Subtype; Influenza, Human; Mesalamine; Mice; Orthomyxoviridae Infections; Pyrazoles; Sulfonamides; Zanamivir | 2008 |
Antiinfluenza medication kits need work, FDA advisers conclude.
Topics: Antiviral Agents; Disease Outbreaks; First Aid; Humans; Influenza, Human; Oseltamivir; United States; United States Food and Drug Administration; Zanamivir | 2008 |
Detection of molecular markers of antiviral resistance in influenza A (H5N1) viruses using a pyrosequencing method.
Topics: Amantadine; Animals; Antiviral Agents; Birds; Drug Resistance, Viral; Genetic Markers; Humans; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Influenza, Human; Neuraminidase; Oseltamivir; Reverse Transcriptase Polymerase Chain Reaction; Rimantadine; RNA, Viral; Sensitivity and Specificity; Sequence Analysis, RNA; Zanamivir | 2009 |
Neuropsychiatric concerns related to influenza treatment.
Topics: Antiviral Agents; Humans; Influenza Vaccines; Influenza, Human; Mental Disorders; Nervous System Diseases; Oseltamivir; Zanamivir | 2009 |
Comparison of the effectiveness of Zanamivir and Oseltamivir against influenza A/H1N1, A/H3N2, and B.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Middle Aged; Oseltamivir; Treatment Outcome; Young Adult; Zanamivir | 2009 |
Update: infections with a swine-origin influenza A (H1N1) virus--United States and other countries, April 28, 2009.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Disease Outbreaks; Female; Humans; Infection Control; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Mexico; Middle Aged; Oseltamivir; Travel; United States; Zanamivir | 2009 |
Swine flu outbreak. What role for antiviral drugs?
Topics: Antiviral Agents; Disease Outbreaks; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Zanamivir | 2009 |
How severe will the flu outbreak be?
Topics: Animals; Antiviral Agents; Disease Outbreaks; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Oseltamivir; Time Factors; Zanamivir | 2009 |
Different neuraminidase inhibitor susceptibilities of human H1N1, H1N2, and H3N2 influenza A viruses isolated in Germany from 2001 to 2005/2006.
Topics: Animals; Cell Line; Dogs; Enzyme Inhibitors; Germany; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Microbial Sensitivity Tests; Mutation; Neuraminidase; Oseltamivir; Phylogeny; Viral Proteins; Zanamivir | 2009 |
Zanamivir: new indication. Influenza: in children as in adults, symptom relief or vaccination.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Drug Approval; Drug Resistance, Viral; Europe; Humans; Influenza Vaccines; Influenza, Human; Zanamivir | 2008 |
Emergence and spread of oseltamivir-resistant A(H1N1) influenza viruses in Oceania, South East Asia and South Africa.
Topics: Acids, Carbocyclic; Amino Acid Substitution; Antiviral Agents; Asia, Southeastern; Cluster Analysis; Cyclopentanes; Drug Resistance, Viral; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Microbial Sensitivity Tests; Mutation, Missense; Neuraminidase; Oceania; Oseltamivir; Phylogeny; RNA, Viral; Sequence Analysis, DNA; Sequence Homology; South Africa; Viral Proteins; Zanamivir | 2009 |
Basic rules of influenza: how to combat the H1N1 influenza (swine flu) virus.
Topics: Antiviral Agents; Disease Outbreaks; Health Planning; Humans; Infectious Disease Incubation Period; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation; Oseltamivir; United States; Vaccination; Zanamivir | 2009 |
Telephone triage of patients with influenza.
Topics: Antiviral Agents; Clinical Protocols; Disease Outbreaks; Family Practice; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mass Screening; Nursing Care; Oseltamivir; Telephone; Triage; Zanamivir | 2009 |
FDA notifications. EUA issued for treating novel 2009 H1N1 flu.
Topics: Antiviral Agents; Child; Child, Preschool; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; United States; United States Food and Drug Administration; Zanamivir | 2009 |
Apropos "vaccines in a hurry".
Topics: Antiviral Agents; Disease Outbreaks; Drug Industry; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Microbial Sensitivity Tests; Oseltamivir; Zanamivir | 2009 |
Swine influenza: nephrologist's perspective.
Topics: Antiviral Agents; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Nephrology; Oseltamivir; Renal Insufficiency, Chronic; Zanamivir | 2009 |
Zanamivir-resistant influenza viruses with a novel neuraminidase mutation.
Topics: Animals; Antiviral Agents; Asia, Southeastern; Australasia; Cell Line; Drug Resistance, Viral; Female; Ferrets; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Microbial Sensitivity Tests; Mutation; Neuraminidase; Orthomyxoviridae Infections; Oseltamivir; Zanamivir | 2009 |
Clinical features of cases of influenza A (H1N1)v in Osaka prefecture, Japan, May 2009.
Topics: Adolescent; Adult; Antigens, Viral; Antiviral Agents; Child; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Japan; Male; Middle Aged; Oseltamivir; Reagent Kits, Diagnostic; Reverse Transcriptase Polymerase Chain Reaction; Schools; Sensitivity and Specificity; Treatment Outcome; Young Adult; Zanamivir | 2009 |
Summary of the Australasian Society for Infectious Diseases and the Thoracic Society of Australia and New Zealand guidelines: treatment and prevention of H1N1 influenza 09 (human swine influenza) with antiviral agents.
Topics: Adult; Antiviral Agents; Child; Child, Preschool; Enzyme Inhibitors; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2009 |
Q&A: What have we found out about the influenza A (H1N1) 2009 pandemic virus?
Topics: Animals; Antiviral Agents; Disease Outbreaks; Drug Resistance, Viral; Humans; Immunity, Active; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Oseltamivir; Time Factors; Virulence; Zanamivir | 2009 |
Why are oseltamivir and zanamivir effective against the newly emerged influenza A virus (A/H1N1)?
Topics: Antiviral Agents; Base Sequence; Binding Sites; Computer Simulation; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza, Human; Molecular Sequence Data; Oseltamivir; Zanamivir | 2009 |
[Inquired of the President of the.Robert Koch Institute. How dangerous is Mexican influenza?].
Topics: Animals; Antiviral Agents; Disease Outbreaks; Enzyme Inhibitors; Germany; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mexico; Orthomyxoviridae Infections; Oseltamivir; Swine; World Health Organization; Zanamivir | 2009 |
[New influenza A (H1N1): advised indication and prescription of antiviral drugs].
Topics: Antiviral Agents; Drug Resistance, Viral; Drug Utilization; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Netherlands; Oseltamivir; Zanamivir | 2009 |
Inhibition of neuraminidase inhibitor-resistant influenza virus by DAS181, a novel sialidase fusion protein.
Topics: Animals; Antiviral Agents; Binding Sites; Caco-2 Cells; Cell Proliferation; Dogs; Humans; Influenza, Human; Mutation; N-Acetylneuraminic Acid; Neuraminidase; Orthomyxoviridae; Oseltamivir; Recombinant Fusion Proteins; Zanamivir | 2009 |
Clinical effectiveness of oseltamivir and zanamivir for treatment of influenza A virus subtype H1N1 with the H274Y mutation: a Japanese, multicenter study of the 2007-2008 and 2008-2009 influenza seasons.
Topics: Adult; Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Female; Fever; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Mutation; Neuraminidase; Oseltamivir; Time Factors; Zanamivir | 2009 |
Host cell selection of influenza neuraminidase variants: implications for drug resistance monitoring in A(H1N1) viruses.
Topics: Acids, Carbocyclic; Amino Acid Substitution; Animals; Antiviral Agents; Cell Line; Cyclopentanes; Dogs; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Inhibitory Concentration 50; Molecular Sequence Data; Mutation, Missense; Neuraminidase; Oseltamivir; RNA, Viral; Sequence Analysis, DNA; Viral Proteins; Zanamivir | 2010 |
Oseltamivir resistance and the H274Y neuraminidase mutation in seasonal, pandemic and highly pathogenic influenza viruses.
Topics: Cross Infection; Drug Resistance, Viral; Global Health; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza B virus; Influenza Vaccines; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Population Surveillance; Rimantadine; Zanamivir | 2009 |
H1N1 influenza in pregnancy: cause for concern.
Topics: Antiviral Agents; Compassionate Use Trials; Extracorporeal Membrane Oxygenation; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Pregnancy; Pregnancy Complications, Infectious; Zanamivir | 2010 |
Intravenous zanamivir for oseltamivir-resistant 2009 H1N1 influenza.
Topics: Antiviral Agents; Child; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Infusions, Intravenous; Investigational New Drug Application; Oseltamivir; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Zanamivir | 2010 |
Homology modeling, docking, and molecular dynamics reveal HR1039 as a potent inhibitor of 2009 A(H1N1) influenza neuraminidase.
Topics: Amino Acid Sequence; Binding Sites; Disaccharides; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Molecular Dynamics Simulation; Molecular Sequence Data; Neuraminidase; Oseltamivir; Plant Extracts; Sequence Alignment; Triterpenes; Zanamivir | 2010 |
Clinical presentation and response to treatment of novel influenza A H1N1 in a university-based summer camp population.
Topics: Adolescent; Antiviral Agents; Disease Outbreaks; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Oseltamivir; Time Factors; Treatment Outcome; United States; Zanamivir | 2010 |
The truth about Tamiflu? Zanamivir should be inhaled, not nebulised.
Topics: Administration, Inhalation; Antiviral Agents; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Nebulizers and Vaporizers; Off-Label Use; Oseltamivir; Zanamivir | 2010 |
Administration of neuraminidase inhibitors for the treatment of Japanese patients infected with the novel influenza A (H1N1).
Topics: Adolescent; Adult; Antiviral Agents; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Japan; Male; Neuraminidase; Oseltamivir; Treatment Outcome; Young Adult; Zanamivir | 2010 |
H1N1 influenza in pregnancy: risks, vaccines, and antivirals.
Topics: Antiviral Agents; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Oseltamivir; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Zanamivir | 2009 |
Fatal respiratory events caused by zanamivir nebulization.
Topics: Adult; Equipment Failure; Fatal Outcome; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Nebulizers and Vaporizers; Oxygen; Pregnancy; Pregnancy Complications, Infectious; Ventilators, Mechanical; Zanamivir | 2010 |
Influenza A/H1N1 (2009) infection in pregnancy--an Asian perspective.
Topics: Administration, Oral; Adolescent; Adult; Antiviral Agents; Cohort Studies; Female; Hospitalization; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Prospective Studies; Singapore; Time Factors; Young Adult; Zanamivir | 2010 |
A two-year survey of the oseltamivir-resistant influenza A(H1N1) virus in Yamagata, Japan and the clinical effectiveness of oseltamivir and zanamivir.
Topics: Adolescent; Amino Acid Substitution; Animals; Antiviral Agents; Cell Line; Child, Preschool; Dogs; Drug Resistance, Viral; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza, Human; Japan; Molecular Epidemiology; Molecular Sequence Data; Mutation, Missense; Neuraminidase; Oseltamivir; Phylogeny; Sequence Analysis, DNA; Treatment Outcome; Viral Proteins; Virulence; Zanamivir | 2010 |
Rare influenza A (H3N2) variants with reduced sensitivity to antiviral drugs.
Topics: Amantadine; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A Virus, H3N2 Subtype; Influenza, Human; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Myanmar; Neuraminidase; Phylogeny; Sequence Analysis, DNA; Viral Matrix Proteins; Viral Proteins; Zanamivir | 2010 |
A close-up view of flu.
Topics: Antiviral Agents; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Nurse Practitioners; Young Adult; Zanamivir | 2010 |
[Controversies about neuraminidase inhibitor. Is the influenza drug less effective than assumed?].
Topics: Adolescent; Adult; Age Factors; Antiviral Agents; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Infant; Influenza A virus; Influenza, Human; Male; Meta-Analysis as Topic; Middle Aged; Neuraminidase; Oseltamivir; Pregnancy; Risk Factors; Seasons; Zanamivir | 2010 |
Oseltamivir-induced resistant pandemic A/H1N1 influenza virus in a child with cystic fibrosis and Pseudomonas aeruginosa infection.
Topics: Antiviral Agents; Child; Cystic Fibrosis; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Mutation; Oseltamivir; Pseudomonas aeruginosa; Pseudomonas Infections; Zanamivir | 2010 |
Intravenous zanamivir for patients with pneumonitis due to pandemic (H1N1) 2009 influenza virus.
Topics: Adult; Antiviral Agents; Critical Illness; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Injections, Intravenous; Male; Middle Aged; Pneumonia; Respiratory Distress Syndrome; Treatment Outcome; Zanamivir | 2010 |
Use of intravenous zanamivir after development of oseltamivir resistance in a critically Ill immunosuppressed child infected with 2009 pandemic influenza A (H1N1) virus.
Topics: Antiviral Agents; Compassionate Use Trials; Critical Illness; Drug Resistance, Viral; Female; Humans; Immunocompromised Host; Infant; Influenza A Virus, H1N1 Subtype; Influenza, Human; Injections, Intravenous; Oseltamivir; Treatment Outcome; Viral Load; Zanamivir | 2010 |
In silico identification of the potential drug resistance sites over 2009 influenza A (H1N1) virus neuraminidase.
Topics: Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Molecular Dynamics Simulation; Neuraminidase; Oseltamivir; Zanamivir | 2010 |
Reduced effectiveness of oseltamivir in children infected with oseltamivir-resistant influenza A (H1N1) viruses with His275Tyr mutation.
Topics: Adolescent; Amino Acid Substitution; Antiviral Agents; Child; Child, Preschool; Drug Resistance, Viral; Female; Fever; Humans; Infant; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza, Human; Japan; Male; Microbial Sensitivity Tests; Mutation, Missense; Nasopharynx; Neuraminidase; Oseltamivir; Treatment Outcome; Viral Proteins; Zanamivir | 2010 |
[Fatal pneumonitis due to oseltamivir-resistant new influenza A(H1N1) in the case of an intensive care patient].
Topics: Antiviral Agents; Drug Resistance, Viral; Fatal Outcome; Humans; Immunocompromised Host; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Oseltamivir; Pneumonia; Zanamivir | 2010 |
Oseltamivir-resistant influenza viruses A (H1N1) during 2007-2009 influenza seasons, Japan.
Topics: Amantadine; Amino Acid Substitution; Antiviral Agents; Drug Resistance, Viral; Hemagglutination Inhibition Tests; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Japan; Neuraminidase; Oseltamivir; Phylogeny; Seasons; Sequence Analysis, Protein; Time Factors; Viral Matrix Proteins; Zanamivir | 2010 |
Antiviral drug susceptibilities of seasonal human influenza viruses in Lebanon, 2008-09 season.
Topics: Amantadine; Animals; Antiviral Agents; Cell Line; Child, Preschool; Dogs; Drug Resistance, Viral; Environmental Monitoring; Epidemiological Monitoring; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Lebanon; Male; Microbial Sensitivity Tests; Oseltamivir; Phylogeny; Seasons; Zanamivir | 2010 |
Fatal respiratory events caused by zanamivir nebulization.
Topics: Administration, Inhalation; Adult; Antiviral Agents; Drug Compounding; Fatal Outcome; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Lactose; Nebulizers and Vaporizers; Pregnancy; Pregnancy Complications, Infectious; Product Labeling; Ventilators, Mechanical; Zanamivir | 2010 |
Influenza A(H1N1) outbreak in a long-term care facility for severely handicapped residents, Slovenia, March-April 2009.
Topics: Adolescent; Adult; Antiviral Agents; Disabled Persons; Disease Outbreaks; Drug Resistance; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Oseltamivir; Residential Facilities; Severity of Illness Index; Slovenia; Young Adult; Zanamivir | 2010 |
An unusual cause of fever in a neonate: influenza A (H1N1) virus pneumonia.
Topics: Antiviral Agents; Fever; Gentamicins; Humans; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Oseltamivir; Pneumonia, Viral; Reverse Transcriptase Polymerase Chain Reaction; Treatment Outcome; Zanamivir | 2010 |
Severe H1N1 infection in a pediatric liver transplant recipient treated with intravenous zanamivir: efficiency and complications.
Topics: Antiviral Agents; Child, Preschool; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Infusions, Intravenous; Liver Transplantation; Respiratory Distress Syndrome; RNA, Viral; Treatment Outcome; Zanamivir | 2010 |
Antiviral susceptibility of avian and swine influenza virus of the N1 neuraminidase subtype.
Topics: Acids, Carbocyclic; Animals; Antiviral Agents; Birds; Catalytic Domain; Cyclopentanes; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza in Birds; Influenza, Human; Models, Molecular; Mutation; Neuraminidase; Orthomyxoviridae Infections; Oseltamivir; Protein Conformation; Species Specificity; Swine; Swine Diseases; Viral Proteins; Zanamivir | 2010 |
Neuraminidase inhibitors for influenza treatment and prevention in healthy adults.
Topics: Adult; Antiviral Agents; Disease Transmission, Infectious; Enzyme Inhibitors; Family; Female; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Primary Prevention; Zanamivir | 2010 |
[Naturally occurring oseltamivir resistance in influenza A].
Topics: Amantadine; Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Zanamivir | 2010 |
Foreword: this issue of the Seton Hall Law Review presents contributions to Preparing for Pharmaceutical Response to Pandemic Influenza, a two-day Symposium held at Seton hall University School of Law in the fall of 2008.
Topics: Animals; Antiviral Agents; Birds; Disease Outbreaks; Global Health; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Influenza Vaccines; Influenza, Human; Oseltamivir; United States; Zanamivir | 2009 |
[Influenza A H1N1v treated with extracorporeal membrane oxygenation].
Topics: Adult; Antiviral Agents; Extracorporeal Membrane Oxygenation; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Pneumonia, Viral; Zanamivir | 2010 |
Influenza antiviral prescribing practices during the 2007-08 and 2008-09 influenza seasons in the setting of increased resistance to oseltamivir among circulating influenza viruses.
Topics: Adamantane; Antiviral Agents; Disease Outbreaks; Drug Resistance, Viral; Drug Utilization; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Oseltamivir; Practice Guidelines as Topic; Practice Patterns, Physicians'; Retrospective Studies; Rimantadine; Seasons; Surveys and Questionnaires; Zanamivir | 2010 |
Oseltamivir-resistant variants of the 2009 pandemic H1N1 influenza A virus are not attenuated in the guinea pig and ferret transmission models.
Topics: Animals; Disease Models, Animal; Drug Resistance, Viral; Ferrets; Guinea Pigs; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation, Missense; Orthomyxoviridae Infections; Oseltamivir; Zanamivir | 2010 |
Successful salvage therapy with inhaled zanamivir in a patient with peramivir-resistant pandemic influenza A (H1N1) 2009 virus.
Topics: Acids, Carbocyclic; Administration, Inhalation; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Multiple Myeloma; Salvage Therapy; Treatment Outcome; Virus Shedding; Zanamivir | 2011 |
Emergence of a multidrug-resistant pandemic influenza A (H1N1) virus.
Topics: Amino Acid Substitution; Antiviral Agents; Child, Preschool; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Fatal Outcome; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Mutation; Neuraminidase; Oseltamivir; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Viral Load; Zanamivir | 2010 |
Feasibility of diagnosing influenza within 24 hours of symptom onset in children 1-3 years of age.
Topics: Antigens, Viral; Antiviral Agents; Child, Preschool; Early Diagnosis; Feasibility Studies; Fluoroimmunoassay; Humans; Infant; Influenza A virus; Influenza B virus; Influenza, Human; Oseltamivir; Point-of-Care Systems; Polymerase Chain Reaction; Reagent Kits, Diagnostic; Sensitivity and Specificity; Zanamivir | 2011 |
Oseltamivir-resistant pandemic (H1N1) 2009 treated with nebulized zanamivir.
Topics: Child, Preschool; Dosage Forms; Drug Resistance, Viral; Humans; Immunocompromised Host; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Mutation; Nebulizers and Vaporizers; Oseltamivir; Pandemics; Zanamivir | 2010 |
Genotypic and phenotypic resistance of pandemic A/H1N1 influenza viruses circulating in Germany.
Topics: Adult; Amino Acid Substitution; Antiviral Agents; Child; Child, Preschool; Drug Resistance, Viral; Female; Germany; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Neuraminidase; Oseltamivir; Viral Matrix Proteins; Viral Proteins; Young Adult; Zanamivir | 2011 |
Resistance and virulence mutations in patients with persistent infection by pandemic 2009 A/H1N1 influenza.
Topics: Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Female; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Immunocompromised Host; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Molecular Sequence Data; Mutation; Neuraminidase; Oseltamivir; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Virulence; Zanamivir | 2011 |
Surfactant therapy and intravenous zanamivir in severe respiratory failure due to persistent influenza A/H1N1 2009 virus infection.
Topics: Acute Disease; Biological Products; Bronchoscopy; Child; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Infusions, Intravenous; Phospholipids; Pulmonary Surfactants; Respiratory Insufficiency; Zanamivir | 2010 |
Peri-operative novel 2009 H1N1 influenza virus infection successfully treated with oseltamivir and zanamivir in a lung transplant recipient.
Topics: Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Lung Transplantation; Oseltamivir; Perioperative Care; Treatment Outcome; Young Adult; Zanamivir | 2011 |
Comparison of the clinical symptoms and the effectiveness of neuraminidase inhibitors for patients with pandemic influenza H1N1 2009 or seasonal H1N1 influenza in the 2007-2008 and 2008-2009 seasons.
Topics: Adolescent; Adult; Antiviral Agents; Enzyme Inhibitors; Female; Fever; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pandemics; Seasons; Young Adult; Zanamivir | 2011 |
Generation and characterization of recombinant pandemic influenza A(H1N1) viruses resistant to neuraminidase inhibitors.
Topics: Acids, Carbocyclic; Amino Acid Substitution; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Microbial Sensitivity Tests; Mutation, Missense; Neuraminidase; Oseltamivir; Pyrrolidines; Recombination, Genetic; Viral Plaque Assay; Viral Proteins; Virus Replication; Zanamivir | 2011 |
Comprehensive assessment of 2009 pandemic influenza A (H1N1) virus drug susceptibility in vitro.
Topics: Acids, Carbocyclic; Adamantane; Amino Acid Substitution; Animals; Antiviral Agents; Cell Line; Cyclopentanes; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Microbial Sensitivity Tests; Mutation, Missense; Neuraminidase; Oseltamivir; Pyrans; Pyrrolidines; Sialic Acids; Viral Plaque Assay; Zanamivir | 2010 |
Antivirals in treatment of H1N1 infection: are they really effective?
Topics: Antiviral Agents; Child; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Treatment Outcome; Zanamivir | 2011 |
Pooled human immunoglobulin therapy in critically Ill patients with pandemic 2009 influenza A(H1N1) pneumonitis and immunoglobulin G2 subclass (IgG2) deficiency.
Topics: Adult; Antiviral Agents; Common Variable Immunodeficiency; Critical Illness; Female; Humans; Immunoglobulin G; Immunoglobulins, Intravenous; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Pneumonia; Pregnancy; Salvage Therapy; Treatment Outcome; Zanamivir | 2011 |
Antiviral treatment of influenza A (H1N1-09) guided by molecular resistance testing in aplasia after allo-SCT.
Topics: Antiviral Agents; Drug Resistance, Viral; Female; Hematopoietic Stem Cell Transplantation; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Middle Aged; Oseltamivir; Zanamivir | 2011 |
Prone position ventilation, recruitment maneuver and intravenous zanamivir in severe refractory hypoxemia caused by influenza A (H1N1).
Topics: Antiviral Agents; Female; Humans; Hypoxia; Influenza A Virus, H1N1 Subtype; Influenza, Human; Middle Aged; Prone Position; Respiration, Artificial; Zanamivir | 2010 |
Resistance to neuraminidase inhibitors.
Topics: Adolescent; Antiviral Agents; Child; Child, Preschool; Drug Resistance, Viral; Humans; Influenza, Human; Neuraminidase; Orthomyxoviridae; Oseltamivir; Virus Shedding; Zanamivir | 2011 |
Frequency of drug-resistant viruses and virus shedding in pediatric influenza patients treated with neuraminidase inhibitors.
Topics: Adolescent; Antiviral Agents; Child; Child, Preschool; Drug Resistance, Viral; Female; Humans; Influenza, Human; Male; Microbial Sensitivity Tests; Nasal Mucosa; Neuraminidase; Orthomyxoviridae; Oseltamivir; Pharynx; RNA, Viral; Sequence Analysis, DNA; Treatment Outcome; Virus Shedding; Zanamivir | 2011 |
Quantification of the anti-influenza drug zanamivir in plasma using high-throughput HILIC-MS/MS.
Topics: Antiviral Agents; Chromatography, Liquid; Humans; Influenza, Human; Plasma; Reference Standards; Tandem Mass Spectrometry; Zanamivir | 2011 |
[In vitro and in vivo effects of a long-acting anti-influenza agent CS-8958 (laninamivir octanoate, Inavir) against pandemic (H1N1) 2009 influenza viruses].
Topics: Administration, Intranasal; Animals; Antiviral Agents; Cells, Cultured; Delayed-Action Preparations; Disease Models, Animal; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Japan; Lung; Mice; Mice, Inbred BALB C; Neuraminidase; Pandemics; Viral Load; Virus Replication; Zanamivir | 2010 |
Oseltamivir-resistant pandemic (H1N1) 2009 virus, Mexico.
Topics: Adamantane; Antiviral Agents; Drug Resistance, Viral; Female; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mexico; Microbial Sensitivity Tests; Neuraminidase; Oseltamivir; Pandemics; Point Mutation; Reverse Transcriptase Polymerase Chain Reaction; Zanamivir | 2011 |
Failure of combination oral oseltamivir and inhaled zanamivir antiviral treatment in ventilator- and ECMO-treated critically ill patients with pandemic influenza A (H1N1)v.
Topics: Administration, Inhalation; Administration, Oral; Adult; Aged; Antiviral Agents; Child; Critical Illness; Drug Therapy, Combination; Extracorporeal Membrane Oxygenation; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Oseltamivir; Respiration, Artificial; Time Factors; Treatment Failure; Virus Shedding; Zanamivir | 2011 |
Safety of influenza immunizations and treatment during pregnancy: the Vaccines and Medications in Pregnancy Surveillance System.
Topics: Adverse Drug Reaction Reporting Systems; Antiviral Agents; Case-Control Studies; Congenital Abnormalities; Female; Humans; Immunization; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Oseltamivir; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Prospective Studies; Risk Assessment; Societies, Medical; United States; Zanamivir | 2011 |
Extracorporeal membrane oxygenation for severe refractory respiratory failure secondary to 2009 H1N1 influenza A.
Topics: Adolescent; Adult; Antiviral Agents; Child; Critical Illness; Extracorporeal Membrane Oxygenation; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Intensive Care Units, Pediatric; Male; Oseltamivir; Respiratory Insufficiency; Retrospective Studies; Young Adult; Zanamivir | 2011 |
Comparison of the efficacies of amantadine treatment of swine-origin influenza virus A H1N1 and seasonal influenza H1N1 and H3N2 in Japan (2008-2009).
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Amantadine; Amino Acid Sequence; Analysis of Variance; Antiviral Agents; Body Temperature; Child; Child, Preschool; Disease Outbreaks; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Japan; Middle Aged; Molecular Sequence Data; Mutation; Oseltamivir; Seasons; Sequence Alignment; Treatment Outcome; Viral Matrix Proteins; Zanamivir | 2011 |
Influenza A virus hemagglutinin antibody escape promotes neuraminidase antigenic variation and drug resistance.
Topics: Amino Acid Substitution; Antibodies, Viral; Antigenic Variation; Antiviral Agents; Drug Resistance, Viral; Hemagglutinins; Humans; Immune Evasion; Influenza A virus; Influenza, Human; Models, Molecular; Mutation; Neuraminidase; Oseltamivir; Zanamivir | 2011 |
Real-time estimation and prediction for pandemic A/H1N1(2009) in Japan.
Topics: Antiviral Agents; Databases, Factual; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Japan; Models, Statistical; Oseltamivir; Pandemics; Population Surveillance; Predictive Value of Tests; Zanamivir | 2011 |
Computational analysis and modeling the effectiveness of 'Zanamivir' targeting neuraminidase protein in pandemic H1N1 strains.
Topics: Antigens, Viral; Antiviral Agents; Computer Simulation; Genetic Drift; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Models, Biological; Neuraminidase; Phylogeny; Zanamivir | 2011 |
Mixed influenza A and B infections complicate the detection of influenza viruses with altered sensitivities to neuraminidase inhibitors.
Topics: Animals; Antiviral Agents; Cell Line; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H2N2 Subtype; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2011 |
Rapid discrimination of oseltamivir-resistant 275Y and -susceptible 275H substitutions in the neuraminidase gene of pandemic influenza A/H1N1 2009 virus by duplex one-step RT-PCR assay.
Topics: Amino Acid Substitution; Animals; Antiviral Agents; Cell Line; Dogs; Drug Resistance, Viral; Genetic Testing; Genotype; Hemagglutination Inhibition Tests; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Japan; Molecular Typing; Mutation, Missense; Neuraminidase; Oseltamivir; Pandemics; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Sequence Analysis, DNA; Viral Proteins; Zanamivir | 2011 |
Online monitoring of flu in Belgium.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Belgium; Child; Child, Preschool; Disease Notification; Hospitalization; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Online Systems; Oseltamivir; Pandemics; Population Surveillance; Young Adult; Zanamivir | 2011 |
Household transmission of influenza (H1N1-2009) in Japan: age-specificity and reduction of household transmission risk by zanamivir treatment.
Topics: Adolescent; Adult; Age Distribution; Antiviral Agents; Child; Child, Preschool; Family Characteristics; Female; Humans; Infant; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza, Human; Japan; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Risk Factors; Time Factors; Young Adult; Zanamivir | 2011 |
Increased detection in Australia and Singapore of a novel influenza A(H1N1)2009 variant with reduced oseltamivir and zanamivir sensitivity due to a S247N neuraminidase mutation.
Topics: Antiviral Agents; Australia; Drug Resistance; Genetic Predisposition to Disease; Genetic Variation; Humans; Incidence; Influenza A Virus, H1N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Polymorphism, Single Nucleotide; Population Surveillance; Risk Assessment; Risk Factors; Singapore; Zanamivir | 2011 |
Severe H1N1-infection during pregnancy.
Topics: Abortion, Spontaneous; Antiviral Agents; Extracorporeal Membrane Oxygenation; Fatal Outcome; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Pregnancy; Pregnancy Complications, Infectious; Respiration, Artificial; Severity of Illness Index; Young Adult; Zanamivir | 2011 |
Use of intravenous neuraminidase inhibitors during the 2009 pandemic: results from population-based surveillance.
Topics: Acids, Carbocyclic; Adult; Child; Child, Preschool; Cyclopentanes; Drug Utilization; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Infusions, Intravenous; Inpatients; Middle Aged; Population Surveillance; Practice Patterns, Physicians'; United States; Zanamivir | 2011 |
Surveillance of illness associated with pandemic (H1N1) 2009 virus infection among adults using a global clinical site network approach: the INSIGHT FLU 002 and FLU 003 studies.
Topics: Adult; Age Distribution; Female; Hospitalization; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Oseltamivir; Pandemics; Population Surveillance; Seasons; Zanamivir | 2011 |
Birth outcomes among women exposed to neuraminidase inhibitors during pregnancy.
Topics: Adult; Antiviral Agents; Cohort Studies; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Enzyme Inhibitors; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Influenza, Human; Male; Maternal Age; Maternal-Fetal Exchange; Neuraminidase; Oseltamivir; Parity; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Risk Factors; Young Adult; Zanamivir | 2011 |
[Etiotropic therapy of influenza: lessons from the last pandemic].
Topics: Antiviral Agents; Communicable Diseases, Emerging; Drug Resistance, Viral; Early Diagnosis; Hemagglutination, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Oseltamivir; Pandemics; Pneumonia, Viral; Prognosis; Severity of Illness Index; Viral Interference; Viral Tropism; Zanamivir | 2011 |
[Clinical features and contagiousness of influenza A(H1N1) in health care workers and hospitalized patients in a Mexico City hospital].
Topics: Adult; Aged; Antiviral Agents; Comorbidity; Contact Tracing; Cross Infection; Disease Outbreaks; Female; Hospital Mortality; Hospitals, Urban; Humans; Immunocompromised Host; Infectious Disease Transmission, Patient-to-Professional; Infectious Disease Transmission, Professional-to-Patient; Influenza A Virus, H1N1 Subtype; Influenza, Human; Inpatients; Male; Mexico; Middle Aged; Neoplasms; Occupational Diseases; Oseltamivir; Personnel, Hospital; Virulence; Zanamivir | 2011 |
Multidrug-resistant pandemic (H1N1) 2009 infection in immunocompetent child.
Topics: Adolescent; Antiviral Agents; Drug Resistance, Multiple, Viral; Enzyme Inhibitors; Female; Humans; Immunocompetence; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Pandemics; Zanamivir | 2011 |
Influenza-associated monophasic neuromyelitis optica.
Topics: Adolescent; Anti-Inflammatory Agents; Antiviral Agents; Aquaporin 4; Autoantibodies; Female; Humans; Influenza A virus; Influenza, Human; Magnetic Resonance Imaging; Methylprednisolone; Neuromyelitis Optica; Prednisolone; Zanamivir | 2011 |
Intravenous zanamivir in critically ill patients due to pandemic 2009 (H1N1) influenza A virus.
Topics: Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Oseltamivir; Pneumonia, Viral; Singapore; Survival Analysis; Zanamivir | 2011 |
Evaluation of the antiviral response to zanamivir administered intravenously for treatment of critically ill patients with pandemic influenza A (H1N1) infection.
Topics: Adolescent; Adult; Child, Preschool; Critical Illness; Drug Therapy, Combination; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza, Human; Infusions, Intravenous; Middle Aged; Netherlands; Oseltamivir; Retrospective Studies; Time Factors; Treatment Outcome; Viral Load; Zanamivir | 2011 |
Novel antiviral activity of neuraminidase inhibitors against an avian influenza a virus.
Topics: Animals; Antiviral Agents; Cell Line; Chickens; Dogs; Humans; Influenza A virus; Influenza in Birds; Influenza, Human; Microscopy, Electron, Scanning; Neuraminidase; Oseltamivir; Virion; Virus Assembly; Zanamivir | 2011 |
Description of antiviral treatment among adults hospitalized with influenza before and during the 2009 pandemic: United States, 2005-2009.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amantadine; Antiviral Agents; Drug Therapy, Combination; Female; Guideline Adherence; Hospitalization; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Odds Ratio; Oseltamivir; Pandemics; Practice Guidelines as Topic; Practice Patterns, Physicians'; Pregnancy; Pregnancy Complications, Infectious; Rimantadine; United States; Young Adult; Zanamivir | 2011 |
Alopecia areata triggered or exacerbated by swine flu virus infection.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Alopecia Areata; Antiviral Agents; Child; Child, Preschool; Cyclobutanes; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Zanamivir | 2012 |
Oseltamivir and early deterioration leading to death: a proportional mortality study for 2009A/H1N1 influenza.
Topics: Adolescent; Adult; Age Distribution; Aged; Antiviral Agents; Child; Child, Preschool; Death, Sudden; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza, Human; Japan; Middle Aged; Oseltamivir; Young Adult; Zanamivir | 2011 |
Drugs: Lines of defence.
Topics: Acids, Carbocyclic; Antiviral Agents; Cyclopentanes; Drug Resistance, Viral; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2011 |
Impact of mutations at residue I223 of the neuraminidase protein on the resistance profile, replication level, and virulence of the 2009 pandemic influenza virus.
Topics: Acids, Carbocyclic; Amino Acid Substitution; Animals; Antiviral Agents; Cell Line; Cyclopentanes; Dogs; Drug Resistance, Viral; Ferrets; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Inhibitory Concentration 50; Male; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Neuraminidase; Orthomyxoviridae Infections; Oseltamivir; Pandemics; Reverse Genetics; Viral Proteins; Virus Replication; Zanamivir | 2012 |
Factors associated with clinical and virological response in patients treated with oseltamivir or zanamivir for influenza A during the 2008-2009 winter.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Bacterial Agents; Antiviral Agents; Female; Humans; Influenza, Human; Male; Middle Aged; Oseltamivir; Severity of Illness Index; Treatment Outcome; Viral Load; Young Adult; Zanamivir | 2013 |
Acute encephalopathy in childhood associated with novel influenza a h1n1 virus infection: clinical and neuroimaging findings.
Topics: Antiviral Agents; Child, Preschool; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Immunoglobulin G; Influenza A Virus, H1N1 Subtype; Influenza, Human; Leukoencephalitis, Acute Hemorrhagic; Neuroimaging; Zanamivir | 2011 |
Virological surveillance and antiviral resistance of human influenza virus in Argentina, 2005-2008.
Topics: Amantadine; Animals; Antiviral Agents; Argentina; Cell Line; Dogs; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza B virus; Influenza, Human; Morbidity; Mutation, Missense; Neuraminidase; Oseltamivir; Point Mutation; Population Surveillance; Seasons; Virus Cultivation; Zanamivir | 2011 |
In vitro neuraminidase inhibitory activities of four neuraminidase inhibitors against influenza viruses isolated in the 2010-2011 season in Japan.
Topics: Acids, Carbocyclic; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Cyclopentanes; Enzyme Inhibitors; Female; Guanidines; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Inhibitory Concentration 50; Japan; Male; Microbial Sensitivity Tests; Middle Aged; Neuraminidase; Oseltamivir; Zanamivir | 2012 |
[Clinical trials and intensive therapy of the swine flu (H1N1)].
Topics: Administration, Inhalation; Adult; Aged; Bilirubin; Disease Outbreaks; Female; Georgia (Republic); Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Intensive Care Units; Male; Middle Aged; Oseltamivir; Zanamivir | 2012 |
Single-dose inhaled laninamivir: registered in Japan and its potential role in control of influenza epidemics.
Topics: Administration, Inhalation; Antiviral Agents; Epidemics; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Japan; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 2013 |
The chemiluminescent neuraminidase inhibition assay: a functional method for detection of influenza virus resistance to the neuraminidase inhibitors.
Topics: Antiviral Agents; Biological Assay; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Kinetics; Luminescence; Luminescent Measurements; Neuraminidase; Oseltamivir; Sequence Analysis, RNA; Software; Viral Proteins; Zanamivir | 2012 |
The fluorescence neuraminidase inhibition assay: a functional method for detection of influenza virus resistance to the neuraminidase inhibitors.
Topics: Antiviral Agents; Biological Assay; Drug Resistance, Viral; Enzyme Inhibitors; Fluorescence; Humans; Influenza, Human; Kinetics; Neuraminidase; Orthomyxoviridae; Oseltamivir; Sequence Analysis, RNA; Software; Spectrometry, Fluorescence; Viral Proteins; Zanamivir | 2012 |
Recovery of influenza B virus with the H273Y point mutation in the neuraminidase active site from a human patient.
Topics: Acids, Carbocyclic; Adult; Antiviral Agents; Catalytic Domain; Cyclopentanes; Drug Resistance, Viral; Guanidines; Humans; Influenza B virus; Influenza, Human; Male; Molecular Sequence Data; Mutation, Missense; Neuraminidase; Oseltamivir; Point Mutation; RNA, Viral; Sequence Analysis, DNA; Zanamivir | 2012 |
Long time scale GPU dynamics reveal the mechanism of drug resistance of the dual mutant I223R/H275Y neuraminidase from H1N1-2009 influenza virus.
Topics: Amino Acid Substitution; Antiviral Agents; Computer Graphics; Computer Simulation; Crystallography, X-Ray; Drug Resistance, Multiple, Viral; Enzyme Inhibitors; History, 21st Century; Humans; Hydrogen Bonding; Influenza A Virus, H1N1 Subtype; Influenza, Human; Models, Molecular; Molecular Dynamics Simulation; Neuraminidase; Oseltamivir; Pandemics; Point Mutation; Protein Conformation; Protein Structure, Secondary; Static Electricity; Zanamivir | 2012 |
Postexposure prophylaxis for influenza in pediatric wards oseltamivir or zanamivir after rapid antigen detection.
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Antigens, Viral; Antiviral Agents; Child; Child, Preschool; Drug Resistance, Viral; Health Personnel; Humans; Infant; Influenza, Human; Inpatients; Orthomyxoviridae; Oseltamivir; Young Adult; Zanamivir | 2012 |
U.S. utilization patterns of influenza antiviral medications during the 2009 H1N1 influenza pandemic.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Drug Prescriptions; Drug Utilization; Female; Humans; Infant; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Oseltamivir; United States; Young Adult; Zanamivir | 2012 |
Increased symptom severity but unchanged neuraminidase inhibitor effectiveness for A(H1N1)pdm09 in the 2010-2011 season: comparison with the previous season and with seasonal A(H3N2) and B.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Enzyme Inhibitors; Female; Fever; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Inhibitory Concentration 50; Male; Middle Aged; Neuraminidase; Oseltamivir; Seasons; Severity of Illness Index; Treatment Outcome; Young Adult; Zanamivir | 2013 |
An uncontrolled open-label, multicenter study to monitor the antiviral activity and safety of inhaled zanamivir (as Rotadisk via Diskhaler device) among Chinese adolescents and adults with influenza-like illness.
Topics: Adolescent; Adult; Antiviral Agents; Female; Humans; Influenza, Human; Male; Middle Aged; Treatment Outcome; Zanamivir | 2012 |
A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase.
Topics: Animals; Antibodies, Monoclonal; Antiviral Agents; Click Chemistry; Fructose-Bisphosphate Aldolase; Humans; Immunoconjugates; Influenza A virus; Influenza, Human; Mice; Models, Molecular; Neuraminidase; Orthomyxoviridae Infections; Zanamivir | 2012 |
Presence of oseltamivir-resistant pandemic A/H1N1 minor variants before drug therapy with subsequent selection and transmission.
Topics: Adolescent; Antiviral Agents; Child, Preschool; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Neuraminidase; Oseltamivir; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Zanamivir | 2012 |
Supply of neuraminidase inhibitors related to reduced influenza A (H1N1) mortality during the 2009-2010 H1N1 pandemic: an ecological study.
Topics: Antiviral Agents; Enzyme Inhibitors; Geography; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Pandemics; Poisson Distribution; Regression Analysis; Socioeconomic Factors; World Health Organization; Zanamivir | 2012 |
Efficient control of pandemic 2009 H1N1 virus infection with intravenous zanamivir despite the lack of immune function.
Topics: Adolescent; Antineoplastic Agents; Antiviral Agents; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Influenza A Virus, H1N1 Subtype; Influenza, Human; Pandemics; Zanamivir | 2012 |
Exacerbation of influenza virus infections in mice by intranasal treatments and implications for evaluation of antiviral drugs.
Topics: Administration, Intranasal; Animals; Antiviral Agents; Dose-Response Relationship, Drug; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Lung; Mice; Mice, Inbred BALB C; N-Acetylneuraminic Acid; Virus Replication; Zanamivir | 2012 |
H1N1 2009 pandemic influenza virus: resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis.
Topics: Adamantane; Amino Acid Substitution; Antiviral Agents; Binding Sites; Crystallography, X-Ray; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Pandemics; Protein Conformation; Zanamivir | 2012 |
[Neuraminidase inhibitors: effects still unclear].
Topics: Administration, Inhalation; Antiviral Agents; Bias; Conflict of Interest; Double-Blind Method; Drug Industry; Humans; Influenza, Human; Length of Stay; Neuraminidase; Oseltamivir; Publication Bias; Randomized Controlled Trials as Topic; Research Design; Zanamivir | 2012 |
The ongoing battle against influenza: Drug-resistant influenza viruses: why fitness matters.
Topics: Antiviral Agents; Drug Resistance, Viral; Genetic Fitness; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Zanamivir | 2012 |
Clinical efficacy of long-acting neuraminidase inhibitor laninamivir octanoate hydrate in postmarketing surveillance.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Child; Female; Fever; Guanidines; Humans; Influenza, Human; Japan; Kaplan-Meier Estimate; Male; Middle Aged; Neuraminidase; Product Surveillance, Postmarketing; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2013 |
Reply to Chan-Tack et al.
Topics: Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Zanamivir | 2013 |
Clinical experience with intravenous zanamivir under an emergency investigational new drug program in the United States.
Topics: Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Zanamivir | 2013 |
Synchronous dynamics of observed and predicted values of anti-influenza drugs in environmental waters during a seasonal influenza outbreak.
Topics: Amantadine; Antiviral Agents; Disease Outbreaks; Environmental Monitoring; Humans; Influenza, Human; Japan; Oseltamivir; Rivers; Sewage; Water Pollutants, Chemical; Zanamivir | 2012 |
Polymer-attached zanamivir inhibits synergistically both early and late stages of influenza virus infection.
Topics: Animals; Antiviral Agents; Dogs; Drug Synergism; Endocytosis; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Madin Darby Canine Kidney Cells; Microscopy, Electron, Transmission; Neuraminidase; Orthomyxoviridae Infections; Peptides; Zanamivir | 2012 |
Neuraminidase inhibitor susceptibility testing of influenza type B viruses in China during 2010 and 2011 identifies viruses with reduced susceptibility to oseltamivir and zanamivir.
Topics: Antiviral Agents; China; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza B virus; Influenza, Human; Microbial Sensitivity Tests; Mutation, Missense; Neuraminidase; Oseltamivir; Zanamivir | 2013 |
Evaluation of recombinant 2009 pandemic influenza A (H1N1) viruses harboring zanamivir resistance mutations in mice and ferrets.
Topics: Animals; Antiviral Agents; Drug Resistance, Viral; Female; Ferrets; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neuraminidase; Viral Proteins; Virus Replication; Zanamivir | 2013 |
Safety evaluation of laninamivir octanoate hydrate through analysis of adverse events reported during early post-marketing phase vigilance.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Antiviral Agents; Child; Delirium; Female; Guanidines; Humans; Influenza, Human; Male; Middle Aged; Pyrans; Sialic Acids; Syncope; Zanamivir | 2013 |
Development of a novel influenza A antiviral assay.
Topics: Animals; Antiviral Agents; Branched DNA Signal Amplification Assay; Cell Line; Dogs; Guanidines; Humans; Influenza A virus; Influenza, Human; Microbial Sensitivity Tests; Nucleocapsid Proteins; Nucleoproteins; Oligonucleotide Probes; Pyrans; Rimantadine; RNA, Viral; Sialic Acids; Viral Core Proteins; Virus Replication; Zanamivir | 2002 |
Economic analysis of influenza vaccination and antiviral treatment for healthy working adults.
Topics: Acetamides; Adolescent; Adult; Antiviral Agents; Computer Simulation; Cost of Illness; Cost-Benefit Analysis; Decision Trees; Drug Costs; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Middle Aged; Oseltamivir; Pyrans; Rimantadine; Sensitivity and Specificity; Sialic Acids; Vaccination; Zanamivir | 2002 |
Summaries for patients. Influenza vaccination or antiviral treatment for healthy working adults: an economic analysis.
Topics: Acetamides; Adolescent; Adult; Antiviral Agents; Computer Simulation; Cost of Illness; Cost-Benefit Analysis; Drug Costs; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Middle Aged; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; Vaccination; Zanamivir | 2002 |
Current strategies for management of influenza in the elderly population.
Topics: Acetamides; Aged; Aged, 80 and over; Chemoprevention; Complementary Therapies; Cost-Benefit Analysis; Disease Management; Guanidines; Health Services for the Aged; Humans; Influenza, Human; Institutionalization; Oseltamivir; Patient Compliance; Population Surveillance; Prevalence; Pyrans; Rimantadine; Sialic Acids; Vaccination; Zanamivir | 2002 |
Influenza prevention 2002-2003.
Topics: Acetamides; Aged; Antiviral Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Guanidines; Headache; Humans; Infant; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; Pregnancy; Pyrans; Sialic Acids; Zanamivir | 2002 |
Zanamivir in the prevention of influenza among healthy adults.
Topics: Administration, Inhalation; Adult; Aged; Antiviral Agents; Evidence-Based Medicine; Guanidines; Humans; Influenza, Human; Middle Aged; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Zanamivir | 1999 |
Zanamivir is an effective treatment for influenza in children undergoing therapy for acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Child; Child, Preschool; Female; Follow-Up Studies; Guanidines; Humans; Influenza, Human; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrans; Risk Assessment; Sialic Acids; Treatment Outcome; Zanamivir | 2002 |
Cost-effectiveness of newer treatment strategies for influenza.
Topics: Acetamides; Adult; Age Distribution; Aged; Aged, 80 and over; Amantadine; Antiviral Agents; Cost-Benefit Analysis; Decision Trees; Diagnostic Tests, Routine; Drug Costs; Female; Guanidines; Humans; Influenza, Human; Male; Middle Aged; Monte Carlo Method; Neuraminidase; Oseltamivir; Pennsylvania; Pyrans; Quality-Adjusted Life Years; Sialic Acids; Zanamivir | 2002 |
[Neuraminidase inhibitor permitted. The first pill against influenza].
Topics: Acetamides; Administration, Inhalation; Administration, Oral; Aged; Antiviral Agents; Child; Child, Preschool; Guanidines; Humans; Infant; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Time Factors; Zanamivir | 2002 |
Risk for respiratory events in a cohort of patients receiving inhaled zanamivir: a retrospective study.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Antiviral Agents; Bronchial Diseases; Child; Cohort Studies; Constriction, Pathologic; Emergency Service, Hospital; Female; Guanidines; Hospitalization; Humans; Influenza, Human; Insurance Claim Reporting; Male; Middle Aged; Pyrans; Retrospective Studies; Risk; Seasons; Sialic Acids; Zanamivir | 2002 |
The effect of zanamivir treatment on influenza complications: a retrospective cohort study.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Cardiovascular Diseases; Child; Child, Preschool; Cohort Studies; Female; Guanidines; Humans; Influenza, Human; Insurance Claim Reporting; Male; Middle Aged; Otitis Media; Pyrans; Respiratory Tract Diseases; Retrospective Studies; Risk; Seasons; Sialic Acids; Zanamivir | 2002 |
[New diagnostic possibilities and medications. Fit for influenza?].
Topics: Acetamides; Administration, Inhalation; Administration, Oral; Aged; Antiviral Agents; Child; Enzyme Inhibitors; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Time Factors; Zanamivir | 2002 |
Bedside rapid flu test and zanamivir prescription in healthy working adults: a cost-benefit analysis.
Topics: Adult; Antiviral Agents; Cost-Benefit Analysis; Decision Trees; Economics, Pharmaceutical; Female; Guanidines; Humans; Influenza, Human; Male; Middle Aged; Pyrans; Sialic Acids; Zanamivir | 2003 |
Logistic issues and potential prescribing costs associated with use of neuraminidase inhibitors for the treatment of influenza in primary care.
Topics: Acetamides; Adolescent; Adult; Aged; Antiviral Agents; Child; Family Practice; Guanidines; Humans; Influenza, Human; Middle Aged; Neuraminidase; Oseltamivir; Patient Acceptance of Health Care; Pyrans; Sialic Acids; State Medicine; United Kingdom; Zanamivir | 2003 |
[Patient assessment for zanamivir therapy (second report) -- a survey of patients with influenza who were prescribed zanamivir during the 2001/2002 season in Japan].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; Female; Guanidines; Humans; Infant; Influenza, Human; Male; Middle Aged; Patient Satisfaction; Pyrans; Sialic Acids; Zanamivir | 2002 |
[Oral neuraminidase inhibitor and an early warning system. New weapons against influenza].
Topics: Acetamides; Adult; Aged; Antiviral Agents; Female; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Neuraminidase; Oseltamivir; Pyrans; Sentinel Surveillance; Sialic Acids; Zanamivir | 2003 |
Compared protective effect of nasal immunoprophylaxis using a new human monoclonal IgM antibody, human polyclonal antibodies, F(ab')2, amantadine, and zanamivir for prophylaxis of influenza A virus pneumonia in mice.
Topics: Amantadine; Animals; Antibodies, Monoclonal; Antiviral Agents; Female; Guanidines; Humans; Immunization, Passive; Immunoglobulin Fab Fragments; Immunoglobulin M; Immunoglobulins, Intravenous; Influenza A virus; Influenza, Human; Mice; Mice, Inbred BALB C; Pneumonia, Viral; Pyrans; Sialic Acids; Zanamivir | 2003 |
We need to determine who benefits most from flu treatments.
Topics: Acetamides; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2003 |
New application method of zanamivir with a straw.
Topics: Administration, Oral; Antiviral Agents; Child; Child, Preschool; Guanidines; Humans; Infant; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 2003 |
Clinical features of influenza a virus infection in older hospitalized persons.
Topics: Aged; Antiviral Agents; Guanidines; Humans; Influenza A virus; Influenza, Human; Inpatients; Pyrans; Sensitivity and Specificity; Sialic Acids; Zanamivir | 2003 |
Management of influenza in adults older than 65 years of age: cost-effectiveness of rapid testing and antiviral therapy.
Topics: Acetamides; Aged; Amantadine; Antiviral Agents; Computer Simulation; Cost-Benefit Analysis; Decision Support Techniques; Guanidines; Humans; Influenza, Human; Oseltamivir; Pyrans; Quality-Adjusted Life Years; Rimantadine; Sensitivity and Specificity; Sialic Acids; Zanamivir | 2003 |
Summaries for patients. Cost-effective management of flu in adults older than 65 years of age.
Topics: Acetamides; Aged; Amantadine; Antiviral Agents; Computer Simulation; Cost-Benefit Analysis; Decision Support Techniques; Guanidines; Humans; Influenza, Human; Oseltamivir; Pyrans; Quality-Adjusted Life Years; Rimantadine; Sensitivity and Specificity; Sialic Acids; Zanamivir | 2003 |
Neuraminidase inhibitors slightly beneficial for shortening flu symptoms.
Topics: Acetamides; Adolescent; Adult; Aged; Antiviral Agents; Child; Double-Blind Method; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Middle Aged; Neuraminidase; Oseltamivir; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Time Factors; Treatment Outcome; Zanamivir | 2003 |
[English meta-analysis on zanamivir and oseltamivir. Knowledge of effects of influenza agents still not sufficient].
Topics: Acetamides; Antiviral Agents; Guanidines; Humans; Influenza, Human; Meta-Analysis as Topic; Oseltamivir; Practice Guidelines as Topic; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2003 |
[Treatment of influenza in children].
Topics: Adamantane; Amantadine; Antiviral Agents; Child; Guanidines; Humans; Influenza, Human; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2003 |
Changes in in vitro susceptibility of influenza A H3N2 viruses to a neuraminidase inhibitor drug during evolution in the human host.
Topics: Animals; Antiviral Agents; Cell Line; Chickens; Cloning, Molecular; Disease Progression; Enzyme Inhibitors; Guanidines; Hemagglutination Tests; Humans; Influenza A virus; Influenza A Virus, H3N2 Subtype; Influenza, Human; Neuraminidase; Plasmids; Pyrans; Reverse Transcriptase Polymerase Chain Reaction; Sialic Acids; Species Specificity; Turkeys; United Kingdom; Viral Plaque Assay; Zanamivir | 2004 |
Influenza-induced tachypnea is prevented in immune cotton rats, but cannot be treated with an anti-inflammatory steroid or a neuraminidase inhibitor.
Topics: Albuterol; Animals; Anti-Inflammatory Agents; Antiviral Agents; Bronchodilator Agents; Disease Models, Animal; Female; Glucocorticoids; Guanidines; Humans; Influenza A virus; Influenza, Human; Male; Neuraminidase; Pyrans; Respiration Disorders; Sialic Acids; Sigmodontinae; Triamcinolone Acetonide; Zanamivir | 2004 |
A novel means of identifying the neuraminidase type of currently circulating human A(H1) influenza viruses.
Topics: Acetamides; Antiviral Agents; Fluorescence; Guanidines; Humans; Influenza A virus; Influenza, Human; Microbial Sensitivity Tests; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Virology; Zanamivir | 2004 |
Surveillance of influenza isolates for susceptibility to neuraminidase inhibitors during the 2000-2002 influenza seasons.
Topics: Acetamides; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Luminescent Measurements; Microbial Sensitivity Tests; Neuraminidase; Oseltamivir; Population Surveillance; Pyrans; Sialic Acids; Zanamivir | 2004 |
Influenza outbreaks in aged-care facilities: staff vaccination and the emerging use of antiviral therapy.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Amantadine; Antiviral Agents; Disease Outbreaks; Female; Guanidines; Homes for the Aged; Humans; Infection Control; Infectious Disease Transmission, Patient-to-Professional; Influenza A virus; Influenza, Human; Middle Aged; Oseltamivir; Pyrans; Sialic Acids; Vaccination; Victoria; Zanamivir | 2004 |
Antiviral treatment and prophylaxis of influenza in primary care: German recommendations.
Topics: Acetamides; Amantadine; Antiviral Agents; Drug Resistance, Viral; Germany; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Oseltamivir; Primary Health Care; Pyrans; Sialic Acids; Zanamivir | 2004 |
Avian influenza should be ruffling our feathers.
Topics: Acetamides; Amantadine; Animals; Antiviral Agents; Asia, Eastern; Asia, Southeastern; Birds; Disease Outbreaks; Guanidines; Humans; Influenza in Birds; Influenza Vaccines; Influenza, Human; International Cooperation; Neuraminidase; Oseltamivir; Pyrans; Rimantadine; Sialic Acids; World Health Organization; Zanamivir | 2004 |
Surveillance for neuraminidase inhibitor resistance in human influenza viruses from Australia.
Topics: Acetamides; Antiviral Agents; Australia; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Microbial Sensitivity Tests; Neuraminidase; Oseltamivir; Population Surveillance; Pyrans; Sialic Acids; Zanamivir | 2003 |
Prevention of influenza in the general population: recommendation statement from the Canadian Task Force on Preventive Health Care.
Topics: Acetamides; Aged; Canada; Guanidines; Health Policy; Humans; Infant; Influenza Vaccines; Influenza, Human; Middle Aged; Neuraminidase; Oseltamivir; Preventive Medicine; Public Health; Pyrans; Risk Factors; Sialic Acids; Zanamivir | 2004 |
Influenza treatment with neuraminidase inhibitors: cost-effectiveness and cost-utility in healthy adults in the United Kingdom.
Topics: Acetamides; Adolescent; Adult; Antiviral Agents; Cost-Benefit Analysis; Decision Support Techniques; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Middle Aged; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; United Kingdom; Zanamivir | 2005 |
Avian flu special: what's in the medicine cabinet?
Topics: Acetamides; Animals; Antiviral Agents; Guanidines; Humans; Influenza, Human; Internationality; Neuraminidase; Orthomyxoviridae; Oseltamivir; Pyrans; Sialic Acids; World Health Organization; Zanamivir | 2005 |
Zanamivir: an influenza virus neuraminidase inhibitor.
Topics: Antiviral Agents; Child; Child, Preschool; Clinical Trials as Topic; Guanidines; Humans; Influenza, Human; Neuraminidase; Orthomyxoviridae; Pyrans; Sialic Acids; Zanamivir | 2005 |
Sensitivity of influenza viruses to zanamivir and oseltamivir: a study performed on viruses circulating in France prior to the introduction of neuraminidase inhibitors in clinical practice.
Topics: Acetamides; Enzyme Inhibitors; France; Guanidines; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2005 |
Sialidase activity of influenza A virus in an endocytic pathway enhances viral replication.
Topics: Animals; Cell Line; Dogs; Endocytosis; Enzyme Inhibitors; Enzyme Stability; Guanidines; Humans; Hydrogen-Ion Concentration; Influenza A virus; Influenza, Human; Male; Mice; Mice, Inbred C57BL; Neuraminidase; Pyrans; Sialic Acids; Transfection; Virus Replication; Zanamivir | 2005 |
Avian flu: isolation of drug-resistant H5N1 virus.
Topics: Acetamides; Adolescent; Adult; DNA Mutational Analysis; Drug Resistance, Viral; Female; Ferrets; Guanidines; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Influenza A Virus, H5N1 Subtype; Influenza, Human; Inhibitory Concentration 50; Mutation; Neuraminidase; Oseltamivir; Polymerase Chain Reaction; Pyrans; Sialic Acids; Zanamivir | 2005 |
Use of antiviral agents and other measures in an influenza pandemic.
Topics: Acetamides; Antiviral Agents; Disease Outbreaks; Guanidines; Humans; Influenza A virus; Influenza, Human; Netherlands; Neuraminidase; Oseltamivir; Practice Guidelines as Topic; Pyrans; Risk; Sialic Acids; Zanamivir | 2005 |
[Influenza prevention in your practice (interview by Waldtraud Paukstadt)].
Topics: Acetamides; Adult; Antiviral Agents; Child; Child, Preschool; Disease Outbreaks; Drug Resistance, Viral; Guanidines; Humans; Infant; Influenza Vaccines; Influenza, Human; Oseltamivir; Pyrans; Sialic Acids; Treatment Outcome; Zanamivir | 2005 |
Star role for bacteria in controlling flu pandemic?
Topics: Acetamides; Animals; Antiviral Agents; Birds; Chemistry, Pharmaceutical; Disease Outbreaks; Drugs, Generic; Escherichia coli; Genetic Engineering; Global Health; Guanidines; Humans; Illicium; Influenza in Birds; Influenza, Human; Oseltamivir; Pyrans; Shikimic Acid; Sialic Acids; Technology, Pharmaceutical; Zanamivir | 2005 |
Oseltamivir resistance--disabling our influenza defenses.
Topics: Acetamides; Binding Sites; Child; Drug Resistance, Viral; Guanidines; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Pyrans; Self Administration; Sialic Acids; Zanamivir | 2005 |
Review says oseltamivir and zanamivir should be kept for epidemics of flu.
Topics: Acetamides; Antiviral Agents; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2006 |
[Nosocomial outbreak of influenza in high-risk hematological patients. Efficacy of control measures and the use of zanamivir].
Topics: Antiviral Agents; Cross Infection; Guanidines; Hematologic Neoplasms; Humans; Immunocompromised Host; Infection Control; Influenza A virus; Influenza, Human; Pyrans; Risk Factors; Sialic Acids; Zanamivir | 2006 |
Oseltamivir resistance in influenza A (H5N1) infection.
Topics: Acetamides; Administration, Inhalation; Administration, Oral; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanidines; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2006 |
Neuraminidase inhibitor-resistant and -sensitive influenza B viruses isolated from an untreated human patient.
Topics: Acetamides; Acids, Carbocyclic; Amino Acid Substitution; Antiviral Agents; Baculoviridae; Base Sequence; Cyclopentanes; Drug Resistance, Viral; Enzyme Inhibitors; Female; Guanidines; Humans; Infant; Influenza B virus; Influenza, Human; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Sequence Data; Neuraminidase; Oseltamivir; Pyrans; Recombinant Proteins; Sialic Acids; Zanamivir | 2006 |
Non-voluntary licensing of antivirals under patent: options the Australian Government should consider in light of a potential bird flu pandemic.
Topics: Acetamides; Animals; Antiviral Agents; Australia; Birds; Drugs, Generic; Guanidines; Health Services Needs and Demand; Humans; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Influenza, Human; Legislation, Drug; Oseltamivir; Patents as Topic; Public Health; Pyrans; Sialic Acids; Zanamivir | 2006 |
Pharmacokinetics and dosage adjustment of oseltamivir and zanamivir in patients with renal failure.
Topics: Antiviral Agents; Enzyme Inhibitors; Humans; Influenza, Human; Kidney Failure, Chronic; Oseltamivir; Zanamivir | 2006 |
Detection of influenza viruses resistant to neuraminidase inhibitors in global surveillance during the first 3 years of their use.
Topics: Antiviral Agents; Drug Resistance, Viral; Enzyme Inhibitors; Global Health; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Neuraminidase; Orthomyxoviridae; Population Surveillance; Pyrans; Sialic Acids; World Health Organization; Zanamivir | 2006 |
Kinetics of influenza A virus infection in humans.
Topics: Administration, Intranasal; Adult; Antiviral Agents; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Interferons; Kinetics; Models, Theoretical; Nose; Pyrans; Sialic Acids; Zanamivir | 2006 |
Symptomatic predictors of influenza virus positivity in children during the influenza season.
Topics: Acetamides; Aging; Antiviral Agents; Child; Child, Preschool; Cough; Fever; Guanidines; Headache; Humans; Infant; Influenza, Human; Logistic Models; Muscular Diseases; Odds Ratio; Oseltamivir; Pyrans; Risk Factors; Seasons; Sialic Acids; Zanamivir | 2006 |
Possible case scenarios and logistic issues in H5N1 pandemic.
Topics: Antiviral Agents; Disease Outbreaks; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Oseltamivir; Severe Acute Respiratory Syndrome; Zanamivir | 2006 |
Increased adamantane resistance in influenza A(H3) viruses in Australia and neighbouring countries in 2005.
Topics: Adamantane; Antiviral Agents; Australia; Drug Resistance, Viral; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Influenza, Human; Mutation; Neuraminidase; Oseltamivir; Phylogeny; Rimantadine; Zanamivir | 2007 |
[Avian influenza pandemic prevention - current research].
Topics: Acetamides; Animals; Antiviral Agents; Disease Outbreaks; Guanidines; Humans; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Models, Animal; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2006 |
Susceptibility of highly pathogenic A(H5N1) avian influenza viruses to the neuraminidase inhibitors and adamantanes.
Topics: Acids, Carbocyclic; Amantadine; Animals; Antiviral Agents; Base Sequence; Birds; Cyclopentanes; Drug Resistance, Viral; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2007 |
Antiviral management of seasonal and pandemic influenza.
Topics: Amantadine; Animals; Antiviral Agents; Clinical Trials as Topic; Disease Outbreaks; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Influenza, Human; Mice; Neuraminidase; Oseltamivir; Rimantadine; Seasons; Zanamivir | 2006 |
Prevention and treatment of influenza in high-risk groups: children, pregnant women, immunocompromised hosts, and nursing home residents.
Topics: Adolescent; Adult; Aged; Animals; Child; Child, Preschool; Clinical Trials as Topic; Disease Outbreaks; Enzyme Inhibitors; Female; Homes for the Aged; Humans; Immunocompromised Host; Infant; Influenza Vaccines; Influenza, Human; Leukemia; Middle Aged; Nursing Homes; Oseltamivir; Pregnancy; Pregnancy Complications, Infectious; Rats; Risk; United States; Vaccination; Zanamivir | 2006 |
[Significance of virological diagnostics for the effective treatment of hospitalized patients infected with influenza virus].
Topics: Adult; Amantadine; Antiviral Agents; Diagnosis, Differential; Fluorescent Antibody Technique; Hospitalization; Humans; Influenza A virus; Influenza, Human; Middle Aged; Oseltamivir; Respiratory Tract Diseases; Reverse Transcriptase Polymerase Chain Reaction; Rimantadine; Treatment Outcome; Zanamivir | 2006 |
Oseltamivir: new indication. Prevention of influenza in at-risk children: vaccination is best.
Topics: Amantadine; Antiviral Agents; Child; Drug Approval; Drug Resistance; Europe; Humans; Influenza Vaccines; Influenza, Human; Oseltamivir; Vaccination; Zanamivir | 2007 |
[Zanamivir for prevention of influenza and in children].
Topics: Adult; Animals; Antiviral Agents; Child; Disease Outbreaks; Enzyme Inhibitors; Humans; Influenza, Human; Neuraminidase; Orthomyxoviridae; Zanamivir | 2007 |
Monitoring of neuraminidase inhibitor resistance among clinical influenza virus isolates in Japan during the 2003-2006 influenza seasons.
Topics: Antiviral Agents; Drug Resistance, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza, Human; Japan; Neuraminidase; Orthomyxoviridae; Oseltamivir; Zanamivir | 2007 |
John F. Enders lecture 2006: antivirals for influenza.
Topics: Antiviral Agents; Drug Design; Drug Resistance, Viral; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Zanamivir | 2007 |
Failure of zanamivir therapy for pneumonia in a bone-marrow transplant recipient infected by a zanamivir-sensitive influenza A (H1N1) virus.
Topics: Antiviral Agents; Bone Marrow Transplantation; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Pneumonia, Viral; Recurrence; Treatment Failure; Zanamivir | 2007 |
General practitioners' management of influenza with or without neuraminidase inhibitors.
Topics: Adolescent; Adult; Antiviral Agents; Cohort Studies; Enzyme Inhibitors; Female; France; Humans; Influenza, Human; Male; Middle Aged; Neuraminidase; Oseltamivir; Physicians, Family; Practice Patterns, Physicians'; Prospective Studies; Time Factors; Zanamivir | 2007 |
Detection of human influenza A (H1N1) and B strains with reduced sensitivity to neuraminidase inhibitors.
Topics: Amino Acid Substitution; Antiviral Agents; Drug Resistance, Viral; France; Humans; Influenza A Virus, H1N1 Subtype; Influenza B virus; Influenza, Human; Inhibitory Concentration 50; Microbial Sensitivity Tests; Mutation, Missense; Neuraminidase; Oseltamivir; Sequence Analysis, DNA; Viral Proteins; Zanamivir | 2008 |
Influenza.
Topics: Amantadine; Antiviral Agents; Humans; Influenza Vaccines; Influenza, Human; Mass Vaccination; Oseltamivir; Rimantadine; Zanamivir | 2008 |
[Influenza in children: what should be considered in prevention and treatment?].
Topics: Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cross-Sectional Studies; Female; Germany; Humans; Infant; Infectious Disease Transmission, Professional-to-Patient; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Neuraminidase; Oseltamivir; Seasons; Zanamivir | 2008 |
Human-like receptor specificity does not affect the neuraminidase-inhibitor susceptibility of H5N1 influenza viruses.
Topics: Animals; Antiviral Agents; Cell Line; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Microbial Sensitivity Tests; Mutation; Neuraminidase; Oseltamivir; Receptors, Virus; Recombination, Genetic; Respiratory Mucosa; Species Specificity; Viral Proteins; Virus Replication; Zanamivir | 2008 |
In vitro evaluation of neuraminidase inhibitors using the neuraminidase-dependent release assay of hemagglutinin-pseudotyped viruses.
Topics: Animals; Antiviral Agents; Cell Line; Chick Embryo; Drug Evaluation, Preclinical; Enzyme Inhibitors; Genes, Reporter; Genetic Engineering; Hemagglutinins, Viral; Humans; Influenza, Human; Leukemia Virus, Murine; Neuraminidase; Orthomyxoviridae; Oseltamivir; Virus Shedding; Zanamivir | 2008 |
Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Topics: Binding Sites; Crystallography, X-Ray; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza, Human; Kinetics; Models, Molecular; Molecular Conformation; Mutation; Neuraminidase; Oseltamivir; Protein Binding; Zanamivir | 2008 |
4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitro.
Topics: Animals; Antiviral Agents; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Mice; Neuraminidase; Pyrans; Sialic Acids; Thymidine; Tritium; Viral Plaque Assay; Virus Replication; Zanamivir | 1993 |
Rational design of potent sialidase-based inhibitors of influenza virus replication.
Topics: Animals; Antiviral Agents; Cell Line; Computer-Aided Design; Disease Models, Animal; Drug Design; Female; Ferrets; Guanidines; Humans; Influenza A virus; Influenza, Human; Mice; Models, Molecular; Neuraminidase; Pyrans; Sheep; Sialic Acids; Viral Plaque Assay; Virus Replication; Zanamivir | 1993 |
Getting ready for the next influenza pandemic.
Topics: Animals; Antigens, Viral; Antiviral Agents; Disease Outbreaks; Guanidines; Humans; Influenza, Human; Neuraminidase; Orthomyxoviridae; Pyrans; Sialic Acids; Zanamivir | 1996 |
A new antiviral agent for influenza--is there a clinical niche?
Topics: Amantadine; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 1997 |
Zanamivir for influenza virus infections.
Topics: Adult; Antiviral Agents; Double-Blind Method; Female; Guanidines; Humans; Influenza, Human; Male; Multicenter Studies as Topic; Pyrans; Randomized Controlled Trials as Topic; Reproducibility of Results; Sialic Acids; Treatment Outcome; Zanamivir | 1998 |
Inhibition of influenza virus infections in mice by GS4104, an orally effective influenza virus neuraminidase inhibitor.
Topics: Acetamides; Administration, Intranasal; Administration, Oral; Amines; Animals; Antiviral Agents; Cell Line; Disease Models, Animal; Dogs; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Lung Diseases; Mice; Mice, Inbred BALB C; Molecular Structure; Neuraminidase; Oseltamivir; Pyrans; Ribavirin; Sialic Acids; Zanamivir | 1998 |
Evidence for zanamivir resistance in an immunocompromised child infected with influenza B virus.
Topics: Amino Acid Substitution; Animals; Antiviral Agents; Bone Marrow Transplantation; Cell Line; Chlorocebus aethiops; Dogs; Drug Resistance, Microbial; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Ferrets; Guanidines; Hemagglutination Inhibition Tests; Humans; Immunosuppression Therapy; Infant; Influenza B virus; Influenza, Human; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mutation; Neuraminidase; Orthomyxoviridae Infections; Pyrans; Receptors, Virus; RNA, Viral; Sialic Acids; Vero Cells; Zanamivir | 1998 |
New ways to tackle influenza highlighted at ICAAC. Interscience Conference on Antimicrobial Agents and Chemotherapy.
Topics: Adolescent; Amines; Child; Child, Preschool; Clinical Trials as Topic; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 1998 |
Characterization of influenza A/HongKong/156/97 (H5N1) virus in a mouse model and protective effect of zanamivir on H5N1 infection in mice.
Topics: Animals; Antiviral Agents; Chick Embryo; Female; Guanidines; Hong Kong; Humans; Influenza A virus; Influenza A Virus, H5N1 Subtype; Influenza, Human; Lung; Mice; Mice, Inbred BALB C; Organ Specificity; Pyrans; Sialic Acids; Virulence; Virus Replication; Zanamivir | 1998 |
Progress treating, preventing influenza.
Topics: Amines; Antiviral Agents; Disease Outbreaks; Enzyme Inhibitors; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 1998 |
Treating influenza with zanamivir.
Topics: Administration, Inhalation; Adult; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 1998 |
The relentless flu drug.
Topics: Antiviral Agents; Clinical Trials as Topic; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Orthomyxoviridae; Pyrans; Sialic Acids; Zanamivir | 1998 |
[A grip grippe?].
Topics: Antiviral Agents; Guanidines; Humans; Incidence; Influenza, Human; Pyrans; Sialic Acids; United States; Zanamivir | 1998 |
[Influenza: new therapeutic perspectives].
Topics: Administration, Intranasal; Animals; Antiviral Agents; Disease Models, Animal; Guanidines; Humans; Influenza A virus; Influenza Vaccines; Influenza, Human; Mice; Prospective Studies; Pyrans; Rodentia; Sialic Acids; Vaccination; Zanamivir | 1998 |
[HIV, hepatitis, influenza: new antiviral agents].
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antiviral Agents; Child; Clinical Trials as Topic; Dideoxynucleosides; Enzyme Inhibitors; Guanidines; Hepatitis B; Humans; Influenza, Human; Lamivudine; Neuraminidase; Pyrans; Reverse Transcriptase Inhibitors; Sialic Acids; Zanamivir | 1999 |
Treating influenza with zanamivir. Management of Influenza in the Southern Hemisphere Trialists.
Topics: Administration, Inhalation; Amantadine; Antiviral Agents; Drug Resistance, Microbial; Guanidines; Humans; Influenza, Human; Orthomyxoviridae; Pyrans; Rimantadine; Sialic Acids; Time Factors; Zanamivir | 1999 |
Treating influenza with zanamivir.
Topics: Administration, Inhalation; Amantadine; Antiviral Agents; Biological Availability; Drug Resistance, Microbial; Guanidines; Humans; Influenza, Human; Orthomyxoviridae; Pyrans; Sialic Acids; Time Factors; Zanamivir | 1999 |
Glaxo's antiviral ills not deemed contagious.
Topics: Antiviral Agents; Drug Approval; Guanidines; Humans; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; United States; United States Food and Drug Administration; Zanamivir | 1999 |
New options for prevention and control of influenza.
Topics: Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 1999 |
Zanamivir for influenza: a public health perspective. Its use will require careful management by GPs.
Topics: Antiviral Agents; Guanidines; Humans; Influenza, Human; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Zanamivir | 1999 |
Inhaled zanamivir approved for influenza treatment.
Topics: Administration, Inhalation; Antiviral Agents; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 1999 |
NICE to rule on influenza flu drug zanamivir.
Topics: Academies and Institutes; Antiviral Agents; Guanidines; Humans; Influenza, Human; National Health Programs; Pyrans; Sialic Acids; Zanamivir | 1999 |
Dobson backed NICE ruling on flu drug.
Topics: Antiviral Agents; Guanidines; Humans; Influenza, Human; Legislation, Drug; Organizational Policy; Pyrans; Sialic Acids; Zanamivir | 1999 |
Flu treatment. A new member of the armamentarium.
Topics: Antiviral Agents; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 1999 |
A nasty start for NICE.
Topics: Aged; Antiviral Agents; Drug Approval; Drug Industry; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; State Medicine; United Kingdom; Zanamivir | 1999 |
Two neuraminidase inhibitors for treatment of influenza.
Topics: Acetamides; Administration, Inhalation; Administration, Oral; Amantadine; Amines; Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Microbial; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Prodrugs; Pyrans; Sialic Acids; Zanamivir | 1999 |
[Neuraminidase inhibitors against influenza].
Topics: Amines; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 1999 |
NICE advises against prescribing zanamivir until further evidence emerges.
Topics: Antiviral Agents; Guanidines; Humans; Influenza, Human; Practice Guidelines as Topic; Pyrans; Risk Factors; Sialic Acids; Zanamivir | 1999 |
[New antivirals for respiratory tract viruses].
Topics: Antiviral Agents; Drug Approval; France; Guanidines; Humans; Influenza, Human; Neuraminidase; Oxadiazoles; Oxazoles; Picornaviridae Infections; Pyrans; Respiratory Tract Infections; Sialic Acids; Zanamivir | 1999 |
Influenza--a new problem?
Topics: Amines; Antiviral Agents; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 1999 |
Do the new flu drugs measure up?
Topics: Acetamides; Antiviral Agents; Guanidines; Humans; Influenza, Human; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 1999 |
Neuraminidase inhibitors for treatment of influenza A and B infections.
Topics: Acetamides; Adolescent; Adult; Antiviral Agents; Drug Interactions; Drug Resistance, Microbial; Enzyme Inhibitors; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 1999 |
By the way, doctor. I am 68 years old and healthy. For the past two years, I've gotten a flu shot in October. Nonetheless, both winters I experienced what felt like influenza. I was thrilled to read about a new flu treatment. If I get the flu again this y
Topics: Aged; Antiviral Agents; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 2000 |
Zanamivir. 4-guanidino Neu5Ac2en, GG 167, GR 121167, GR 121167X, Relenza.
Topics: Antiviral Agents; Clinical Trials as Topic; Drug Interactions; Guanidines; Humans; Influenza, Human; Orthomyxoviridae; Pyrans; Sialic Acids; Zanamivir | 1999 |
Zanamivir, influenza, and meningococcal disease. Zanamivir may help to fight potential flu epidemic.
Topics: Antiviral Agents; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 2000 |
Respiratory distress associated with zanamivir.
Topics: Antiviral Agents; Bronchial Spasm; Guanidines; Humans; Influenza, Human; Lung Diseases, Obstructive; Male; Middle Aged; Neuraminidase; Pyrans; Respiratory Insufficiency; Sialic Acids; Zanamivir | 2000 |
Zanamivir, influenza, and meningococcal disease. NHS regulations are of questionable legality.
Topics: Antiviral Agents; Guanidines; Humans; Influenza, Human; Legislation, Drug; Pyrans; Sialic Acids; State Medicine; United Kingdom; Zanamivir | 2000 |
Implications of the Relenza ruling.
Topics: Antiviral Agents; Decision Making; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; State Medicine; United Kingdom; Zanamivir | 2000 |
Neuraminidase inhibitors and relief of influenza symptoms.
Topics: Acetamides; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2000 |
[Influenza: from vaccine prevention to antiviral therapy].
Topics: Administration, Inhalation; Antiviral Agents; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 2000 |
[New flu therapy. Progress or burden for the budget?].
Topics: Acetamides; Antiviral Agents; Cost-Benefit Analysis; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2000 |
New influenza drug offers some help.
Topics: Antiviral Agents; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 1999 |
Influenza in the family.
Topics: Administration, Inhalation; Antiviral Agents; Disease Transmission, Infectious; Family Health; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 2000 |
Clinical signs and symptoms predicting influenza infection.
Topics: Adolescent; Adult; Antiviral Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cough; Diagnosis, Differential; Double-Blind Method; Female; Fever; Guanidines; Humans; Influenza, Human; Male; Middle Aged; Multicenter Studies as Topic; Multivariate Analysis; Pharyngitis; Predictive Value of Tests; Pyrans; Retrospective Studies; Sialic Acids; Time Factors; Zanamivir | 2000 |
Zanamivir use during transmission of amantadine-resistant influenza A in a nursing home.
Topics: Activities of Daily Living; Administration, Inhalation; Aged; Aged, 80 and over; Amantadine; Antiviral Agents; Disease Outbreaks; Drug Resistance, Microbial; Guanidines; Homes for the Aged; Humans; Influenza A virus; Influenza, Human; Middle Aged; Nursing Homes; Ontario; Patient Compliance; Pyrans; Sialic Acids; Zanamivir | 2000 |
Antiviral agents for influenza.
Topics: Acetamides; Adolescent; Adult; Aged; Amantadine; Antiviral Agents; Child; Child, Preschool; Guanidines; Guidelines as Topic; Humans; Infant; Influenza, Human; Middle Aged; Oseltamivir; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Treatment Outcome; Zanamivir | 2000 |
Effect of zanamivir on duration and resolution of influenza symptoms.
Topics: Administration, Inhalation; Adult; Aged; Antiviral Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Guanidines; Humans; Influenza, Human; Middle Aged; Neuraminidase; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Zanamivir | 2000 |
Guidance on the use of the anti-influenza drug, zanamivir.
Topics: Adult; Enzyme Inhibitors; Female; Guanidines; Guidelines as Topic; Humans; Influenza, Human; Male; Pyrans; Sensitivity and Specificity; Sialic Acids; Treatment Outcome; United Kingdom; Zanamivir | 2000 |
Influenza and the new antivirals: potential for misdiagnosis and possible misuse of antivirals.
Topics: Antiviral Agents; Canada; Diagnostic Errors; Guanidines; Health Services Misuse; Humans; Influenza, Human; Male; Middle Aged; Pyrans; Sialic Acids; Zanamivir | 2000 |
Study allays therapy concern, finds new flu drug safe for patients with asthma, COPD.
Topics: Antiviral Agents; Asthma; Guanidines; Humans; Influenza, Human; Lung Diseases, Obstructive; Pyrans; Risk; Sialic Acids; Zanamivir | 2000 |
Flu-fighting options: decisions, decisions....
Topics: Acetamides; Amantadine; Antiviral Agents; Guanidines; Humans; Influenza, Human; Oseltamivir; Pneumonia; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2000 |
Zanamivir. No noticeable progress against influenza.
Topics: Amantadine; Antiviral Agents; Cost-Benefit Analysis; Drug Costs; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 2000 |
Flu drugs. Have I got news for flu.
Topics: Acetamides; Drug Approval; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; United Kingdom; Zanamivir | 2000 |
Zanamivir to prevent influenza.
Topics: Antiviral Agents; Family; Guanidines; Humans; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 2001 |
Zanamivir to prevent influenza.
Topics: Antiviral Agents; Cost-Benefit Analysis; Family; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Pyrans; Sialic Acids; Zanamivir | 2001 |
[New preparations against influenza].
Topics: Antiviral Agents; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 2001 |
Cost-effectiveness analysis of inhaled zanamivir in the treatment of influenza A and B in high-risk patients.
Topics: Administration, Inhalation; Adult; Aged; Antiviral Agents; Cost-Benefit Analysis; Female; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Male; Middle Aged; Pyrans; Sialic Acids; Zanamivir | 2001 |
Does the availability of a neuraminidase inhibitor impair influenza vaccination? A report from Austria.
Topics: Antiviral Agents; Austria; Enzyme Inhibitors; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Vaccination; Zanamivir | 2001 |
Advances in pharmacology. New treatments for influenza: neuraminidase inhibitors.
Topics: Acetamides; Antiviral Agents; Drug Approval; Guanidines; Humans; Influenza, Human; Neuraminidase; Oseltamivir; Pyrans; Sensitivity and Specificity; Sialic Acids; United States; Zanamivir | 2001 |
Elderly people's technique in using dry powder inhalers. Zanamivir and unreason seem to go together.
Topics: Aged; Antiviral Agents; Enzyme Inhibitors; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Nebulizers and Vaporizers; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 2001 |
Unprepared for an influenza pandemic.
Topics: Acetamides; Amantadine; Antiviral Agents; Disease Outbreaks; Drug Resistance, Microbial; Guanidines; Humans; Influenza, Human; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2001 |
Virology. The origin and control of pandemic influenza.
Topics: Animals; Antiviral Agents; Chickens; Drug Industry; Drug Resistance, Microbial; Enzyme Inhibitors; Guanidines; HN Protein; Hong Kong; Humans; Influenza A virus; Influenza Vaccines; Influenza, Human; Models, Molecular; Mutation; Neuraminidase; Protein Conformation; Pyrans; Reassortant Viruses; RNA, Viral; Sialic Acids; Zanamivir | 2001 |
ACIP releases guidelines on the prevention and control of influenza. Advisory Committee on Immunization Practices.
Topics: Acetamides; Age Factors; Amantadine; Antiviral Agents; Drug Administration Schedule; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Oseltamivir; Patient Selection; Pyrans; Rimantadine; Sialic Acids; Zanamivir | 2001 |
[Patient assessment for zanamivir therapy--a survey of patients with influenza who were prescribed zanamivir during the 2000/2001 season in Japan].
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Antiviral Agents; Guanidines; Humans; Influenza, Human; Middle Aged; Patient Satisfaction; Pyrans; Sialic Acids; Surveys and Questionnaires; Zanamivir | 2001 |
Rapid pharmacotherapeutic intervention for an influenza A outbreak in the Canadian Arctic: lessons from the Sanikiluaq experience.
Topics: Adult; Aged; Antiviral Agents; Arctic Regions; Canada; Disease Outbreaks; Female; Guanidines; Humans; Influenza A virus; Influenza, Human; Middle Aged; Pregnancy; Pyrans; Reagent Kits, Diagnostic; Sialic Acids; Zanamivir | 2001 |
Clinical effectiveness and cost effectiveness of zanamivir (Relenza): translating the evidence into clinical practice, a National Institute for Clinical Excellence view.
Topics: Antiviral Agents; Evidence-Based Medicine; Government Agencies; Guanidines; Health Care Costs; Humans; Influenza, Human; Organizational Objectives; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; United Kingdom; Zanamivir | 2001 |
Zanamivir: an alternative translation.
Topics: Antiviral Agents; Evidence-Based Medicine; Government Agencies; Guanidines; Humans; Influenza, Human; Practice Guidelines as Topic; Pyrans; Sialic Acids; United Kingdom; Zanamivir | 2001 |
[Drug regulatory agency comments on the editorial about the new influenza drugs].
Topics: Antiviral Agents; Drug Approval; Enzyme Inhibitors; Finland; Guanidines; Humans; Influenza, Human; Neuraminidase; Pyrans; Sialic Acids; Zanamivir | 2000 |
Influenza vaccine, anti-influenza drugs, and rapid diagnosis in Japan.
Topics: Amantadine; Antiviral Agents; Child; Child, Preschool; Guanidines; Humans; Influenza Vaccines; Influenza, Human; Male; Neuraminidase; Pyrans; Reagent Kits, Diagnostic; Sialic Acids; Vaccination; Zanamivir | 2000 |
Zanamivir (Relenza )--a new treatment for influenza.
Topics: Age Factors; Aged; Antiviral Agents; Child; Drug Prescriptions; Guanidines; Humans; Influenza, Human; Patient Selection; Public Health; Pyrans; Sialic Acids; United Kingdom; Vaccination; Zanamivir | 1999 |
Are we ready for the next flu pandemic?
Topics: Acetamides; Adult; Antiviral Agents; Disease Outbreaks; Enzyme Inhibitors; Global Health; Guanidines; Humans; Influenza, Human; Neuraminidase; Orthomyxoviridae; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2001 |
[Pneumonia diagnosis in the practice on the test-bench: how much diagnosis is necessary?].
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Diagnosis, Differential; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza, Human; Male; Neuraminidase; Oseltamivir; Pneumonia; Pyrans; Research; Sialic Acids; Time Factors; Zanamivir | 2002 |
Evidence-based emergency medicine/systematic review abstract. Use of the neuraminidase inhibitor class of antiviral drugs for treatment of healthy adults with an acute influenza-like illness.
Topics: Acetamides; Adolescent; Adult; Age Factors; Antiviral Agents; Confidence Intervals; Emergency Medicine; Enzyme Inhibitors; Evidence-Based Medicine; Guanidines; Humans; Influenza, Human; Middle Aged; Neuraminidase; Oseltamivir; Pyrans; Randomized Controlled Trials as Topic; Sialic Acids; Systematic Reviews as Topic; Time Factors; Treatment Outcome; Zanamivir | 2002 |
Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP).
Topics: Acetamides; Adolescent; Adult; Aged; Amantadine; Antiviral Agents; Child; Child, Preschool; Cost-Benefit Analysis; Guanidines; Humans; Infant; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Middle Aged; Oseltamivir; Pyrans; Rimantadine; Risk Factors; Sialic Acids; United States; Vaccination; Zanamivir | 2002 |
Susceptibility of recent Canadian influenza A and B virus isolates to different neuraminidase inhibitors.
Topics: Acetamides; Acids, Carbocyclic; Canada; Cyclopentanes; Drug Resistance, Viral; Enzyme Inhibitors; Fluorometry; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Inhibitory Concentration 50; Luminescent Measurements; Neuraminidase; Oseltamivir; Pyrans; Sialic Acids; Zanamivir | 2002 |