Page last updated: 2024-11-05

zaleplon and Long Sleeper Syndrome

zaleplon has been researched along with Long Sleeper Syndrome in 9 studies

zaleplon: an azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; a hypnotic with less marked effect on psychomotor functions compared to lorazepam
zaleplon : A pyrazolo[1,5-a]pyrimidine having a nitrile group at position 3 and a 3-(N-ethylacetamido)phenyl substituent at the 7-position.

Research Excerpts

ExcerptRelevanceReference
"To assess the effects of zolpidem and zaleplon on nocturnal sleep and breathing patterns at altitude, as well as on daytime attention, fatigue, and sleepiness."5.12Zaleplon and zolpidem objectively alleviate sleep disturbances in mountaineers at a 3,613 meter altitude. ( Batéjat, D; Beaumont, M; Jouanin, JC; Léger, D; Philippe, M; Piérard, C; Savourey, G; Van Beers, P, 2007)
"Sleep disturbance is common in dementia and often treated with Z-drugs (zopiclone, zaleplon, and zolpidem)."3.96Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study. ( Aldus, C; Arthur, A; Ballard, C; Boyd, PJ; Fox, C; Howard, R; Loke, YK; Maidment, I; Richardson, K; Savva, GM; Steel, N, 2020)
"For the symptomatic drug treatment of insomnias, the specific metabolic and pharmacokinetic, as well as possible interactions, should be considered."2.42[Drug treatment of sleep disorders in the elderly]. ( Wiegand, MH, 2003)
"Zaleplon (ZLP) was used as a model drug intended to induce sleep and to treat middle of night insomnia."1.48Zaleplon loaded bi-layered chronopatch: A novel buccal chronodelivery approach to overcome circadian rhythm related sleep disorder. ( Abd El Malak, NS; Farag, MM; Yehia, SA, 2018)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's3 (33.33)29.6817
2010's4 (44.44)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Choi, Y1
Raymer, BK1
Richardson, K1
Loke, YK1
Fox, C1
Maidment, I1
Howard, R1
Steel, N1
Arthur, A1
Boyd, PJ1
Aldus, C1
Ballard, C1
Savva, GM1
Farag, MM1
Abd El Malak, NS1
Yehia, SA1
Molina, SM1
Joshi, KG1
Verster, JC1
Roth, T1
Wiegand, MH1
Beaumont, M1
Batéjat, D1
Piérard, C1
Van Beers, P1
Philippe, M1
Léger, D1
Savourey, G1
Jouanin, JC1
Yamadera, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of High-altitude Sleep Disturbance: A Double-blind Comparison of Temazepam Versus Acetazolamide.[NCT01519544]34 participants (Actual)Interventional2012-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for zaleplon and Long Sleeper Syndrome

ArticleYear
Sleep modulating agents.
    Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16

    Topics: Animals; Humans; Sleep; Sleep Aids, Pharmaceutical; Sleep Wake Disorders; Wakefulness-Promoting Agen

2019
Gender differences in highway driving performance after administration of sleep medication: a review of the literature.
    Traffic injury prevention, 2012, Volume: 13, Issue:3

    Topics: Acetamides; Automobile Driving; Azabicyclo Compounds; Environment Design; Female; Flurazepam; Humans

2012
[Drug treatment of sleep disorders in the elderly].
    Der Internist, 2003, Volume: 44, Issue:9

    Topics: Acetamides; Aged; Aged, 80 and over; Antidepressive Agents; Antipsychotic Agents; Azabicyclo Compoun

2003
[Recent progress in development of hypnotic drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56, Issue:2

    Topics: Acetamides; Animals; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Female; Humans;

1998

Trials

1 trial available for zaleplon and Long Sleeper Syndrome

ArticleYear
Zaleplon and zolpidem objectively alleviate sleep disturbances in mountaineers at a 3,613 meter altitude.
    Sleep, 2007, Volume: 30, Issue:11

    Topics: Acetamides; Altitude; Attention; Cross-Over Studies; Disorders of Excessive Somnolence; Double-Blind

2007

Other Studies

4 other studies available for zaleplon and Long Sleeper Syndrome

ArticleYear
Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study.
    BMC medicine, 2020, 11-24, Volume: 18, Issue:1

    Topics: Acetamides; Aged, 80 and over; Azabicyclo Compounds; Cohort Studies; Dementia; Female; Humans; Male;

2020
Zaleplon loaded bi-layered chronopatch: A novel buccal chronodelivery approach to overcome circadian rhythm related sleep disorder.
    International journal of pharmaceutics, 2018, May-05, Volume: 542, Issue:1-2

    Topics: Acetamides; Administration, Buccal; Animals; Biological Availability; Capsules; Delayed-Action Prepa

2018
A case of zaleplon-induced amnestic sleep-related eating disorder.
    The Journal of clinical psychiatry, 2010, Volume: 71, Issue:2

    Topics: Acetamides; Amnesia; Dose-Response Relationship, Drug; Feeding and Eating Disorders; Female; Humans;

2010
Sleeping pills without regrets. They've long been the risky quick fixes of sleep medicine. Soon some sleeping pills may be sold as long-term solutions.
    Harvard health letter, 2004, Volume: 29, Issue:10

    Topics: Acetamides; Age Factors; Azabicyclo Compounds; Benzodiazepines; Humans; Hypnotics and Sedatives; Pip

2004