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zaleplon and Drug Withdrawal Symptoms

zaleplon has been researched along with Drug Withdrawal Symptoms in 8 studies

zaleplon: an azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; a hypnotic with less marked effect on psychomotor functions compared to lorazepam
zaleplon : A pyrazolo[1,5-a]pyrimidine having a nitrile group at position 3 and a 3-(N-ethylacetamido)phenyl substituent at the 7-position.

Research Excerpts

ExcerptRelevanceReference
"Zaleplon is a short-acting pyrazolopyrimidine hypnotic with a rapid onset of action."2.69Sleep latency is shortened during 4 weeks of treatment with zaleplon, a novel nonbenzodiazepine hypnotic. Zaleplon Clinical Study Group. ( Elie, R; Emilien, G; Farr, I; Rüther, E; Salinas, E, 1999)
"Zaleplon is a pyrazolopyrimidine hypnotic agent which is indicated for the short term (2 to 4 weeks) management of insomnia."2.41Zaleplon: a review of its use in the treatment of insomnia. ( Dooley, M; Plosker, GL, 2000)
"Transient and chronic insomnia are common problems that should be clinically evaluated and appropriately treated."2.41Safety of zaleplon in the treatment of insomnia. ( Israel, AG; Kramer, JA, 2002)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's6 (75.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Marsden, J1
White, M1
Annand, F1
Burkinshaw, P1
Carville, S1
Eastwood, B1
Kelleher, M1
Knight, J1
O'Connor, R1
Tran, A1
Willey, P1
Greaves, F1
Taylor, S1
Biggio, F2
Gorini, G1
Caria, S1
Murru, L1
Sanna, E1
Follesa, P2
Belleville, G1
Morin, CM1
Siriwardena, AN1
Qureshi, MZ1
Dyas, JV1
Middleton, H1
Orner, R1
Elie, R1
Rüther, E1
Farr, I1
Emilien, G1
Salinas, E1
Dooley, M1
Plosker, GL1
Mancuso, L1
Cagetti, E1
Franco, M1
Trapani, G1
Biggio, G1
Israel, AG1
Kramer, JA1

Reviews

3 reviews available for zaleplon and Drug Withdrawal Symptoms

ArticleYear
Medicines associated with dependence or withdrawal: a mixed-methods public health review and national database study in England.
    The lancet. Psychiatry, 2019, Volume: 6, Issue:11

    Topics: Acetamides; Adolescent; Adult; Aged; Analgesics; Analgesics, Opioid; Antidepressive Agents; Azabicyc

2019
Zaleplon: a review of its use in the treatment of insomnia.
    Drugs, 2000, Volume: 60, Issue:2

    Topics: Acetamides; Drug Interactions; Humans; Hypnotics and Sedatives; Memory; Psychomotor Performance; Pyr

2000
Safety of zaleplon in the treatment of insomnia.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:5

    Topics: Acetamides; Benzodiazepines; Half-Life; Humans; Hypnotics and Sedatives; Psychomotor Disorders; Pyri

2002

Trials

2 trials available for zaleplon and Drug Withdrawal Symptoms

ArticleYear
Hypnotic discontinuation in chronic insomnia: impact of psychological distress, readiness to change, and self-efficacy.
    Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2008, Volume: 27, Issue:2

    Topics: Acetamides; Adaptation, Psychological; Adult; Aged; Anxiety; Attitude to Health; Azabicyclo Compound

2008
Sleep latency is shortened during 4 weeks of treatment with zaleplon, a novel nonbenzodiazepine hypnotic. Zaleplon Clinical Study Group.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:8

    Topics: Acetamides; Adolescent; Adult; Aged; Ambulatory Care; Dose-Response Relationship, Drug; Double-Blind

1999

Other Studies

3 other studies available for zaleplon and Drug Withdrawal Symptoms

ArticleYear
Flumazenil selectively prevents the increase in alpha(4)-subunit gene expression and an associated change in GABA(A) receptor function induced by ethanol withdrawal.
    Journal of neurochemistry, 2007, Volume: 102, Issue:3

    Topics: Acetamides; Alcohol-Induced Disorders, Nervous System; Animals; Animals, Newborn; Anticonvulsants; C

2007
Magic bullets for insomnia? Patients' use and experiences of newer (Z drugs) versus older (benzodiazepine) hypnotics for sleep problems in primary care.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2008, Volume: 58, Issue:551

    Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Attitude to Health; Azabicyclo Compounds; Be

2008
Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, zaleplon or zolpidem.
    Neuropharmacology, 2002, Volume: 42, Issue:2

    Topics: Acetamides; Animals; Cells, Cultured; Diazepam; GABA Modulators; Hypnotics and Sedatives; Nuclease P

2002