Page last updated: 2024-08-22

zalcitabine and Peripheral Nerve Diseases

zalcitabine has been researched along with Peripheral Nerve Diseases in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.71)18.7374
1990's17 (48.57)18.2507
2000's9 (25.71)29.6817
2010's6 (17.14)24.3611
2020's1 (2.86)2.80

Authors

AuthorsStudies
Galeotti, N; Herdegen, T; Manassero, G; Sanna, MD; Vercelli, A1
Galeotti, N; Ghelardini, C; Quattrone, A; Sanna, MD1
Galeotti, N; Ghelardini, C; Mello, T; Quattrone, A; Sanna, MD1
Galeotti, N; Ghelardini, C; Peroni, D; Quattrone, A; Sanna, MD1
Garcia-Perez, E; Serra, J; SolĂ , R; Sumalla, M1
Blackbeard, J; Dickenson, AH; Hasnie, FS; Hosseini, R; Jina, N; Maratou, K; McMahon, SB; Okuse, K; Orengo, C; Pheby, T; Rice, AS; Wallace, VC1
Ferrari, LF; Levine, JD1
Blackbeard, J; Field, MJ; Hasnie, F; O'Dea, KP; Pheby, T; Rice, AS; Segerdahl, A; Takata, M; Wallace, VC1
Mukai, E1
Joseph, EK; Levine, JD1
Chen, X; Levine, JD1
Blackbeard, J; Hasnie, F; McMahon, SB; Pheby, T; Rice, AS; Segerdahl, AR; Wallace, VC1
Bernard, R; Bourgoin, S; Brisorgueil, MJ; Conrath, M; Fischer, J; Gingrich, JA; Hamon, M; Van Steenwinckel, J; Vergé, D1
Arenas-Pinto, A; Bhaskaran, K; Dunn, D; Weller, IV1
Clifford, DB; Fichtenbaum, CJ; Powderly, WG1
Simpson, DM; Tagliati, M1
Cupler, EJ; Dalakas, MC1
Antoniskis, D; Arezzo, J; Bigley, J; Bozzette, SA; Fischl, MA; Gelb, LD; Gocke, DJ; Grieco, MH; Hirsch, MS; Hyslop, NE; Leedom, JM; Lim, L; LoFaro, ML; McKinley, GF; Merigan, TC; Murphy, RL; Pettinelli, CB; Pottage, JC; Powderly, WG; Ray, G; Reed, N; Richman, DD; Schaumburg, HH; Simon, G; Skowron, G; Soo, W; Spector, SA; Sperber, SJ; Uttamchandani, RB; Zachary, J1
Hobbs, GA; Keilbaugh, SA; Simpson, MV1
Arezzo, JC; Berger, AR; Bozzette, S; Merigan, T; Richman, D; Schaumburg, HH; Skowron, G; Soo, W1
French, MA; Martinez, OP1
Boswell, W; Buckley, J; Espina, B; Gill, PS; Levine, AM; Nathwani, B; Parker, J; Rasheed, S; Stain, S; Tulpule, A1
De Simone, C; Famularo, G; Longo, A; Marcellini, S; Moretti, S; Santini, G; Trinchieri, V; Tzantzoglou, S1
Moyle, GJ; Sadler, M1
Cross, A; Dunkle, L; Kelleher, T1
Carey, P1
Conant, M1
Dalakas, MC; Leon-Monzon, M; Semino-Mora, C1
Anderson, TD; Arceo, R; Arezzo, J; Brosnan, C; Davidovich, A; Schaumburg, H1
Anderson, TD; Brosnan, C; Feldman, D1
Keilbaugh, SA; Prusoff, WH; Simpson, MV1
LeLacheur, SF; Simon, GL1
Broder, S; Dalakas, M; Dubinsky, RM; Yarchoan, R2

Reviews

5 review(s) available for zalcitabine and Peripheral Nerve Diseases

ArticleYear
[Neuromuscular diseases associated with HIV-1 infection].
    No to shinkei = Brain and nerve, 2004, Volume: 56, Issue:4

    Topics: Anti-HIV Agents; Cytomegalovirus Infections; HIV Infections; Humans; Neuritis; Neuromuscular Diseases; Peripheral Nervous System Diseases; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Zalcitabine; Zidovudine

2004
Nucleoside analogue-associated peripheral neuropathy in human immunodeficiency virus infection.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Jun-01, Volume: 9, Issue:2

    Topics: Animals; Didanosine; Dideoxynucleosides; Disease Models, Animal; HIV Infections; Humans; Peripheral Nervous System Diseases; Stavudine; Zalcitabine

1995
Peripheral neuropathy with nucleoside antiretrovirals: risk factors, incidence and management.
    Drug safety, 1998, Volume: 19, Issue:6

    Topics: Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Peripheral Nervous System Diseases; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine

1998
Relation of peripheral neuropathy to HIV treatment in four randomized clinical trials including didanosine.
    Clinical therapeutics, 1999, Volume: 21, Issue:7

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Child, Preschool; Data Collection; Didanosine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Polypharmacy; Randomized Controlled Trials as Topic; Risk Factors; Time Factors; Zalcitabine; Zidovudine

1999
Peripheral neuropathy: zalcitabine reassessed.
    International journal of STD & AIDS, 2000, Volume: 11, Issue:7

    Topics: Anti-HIV Agents; HIV Infections; Humans; Peripheral Nervous System Diseases; Reverse Transcriptase Inhibitors; Risk Factors; Zalcitabine

2000

Trials

5 trial(s) available for zalcitabine and Peripheral Nerve Diseases

ArticleYear
The risk of developing peripheral neuropathy induced by nucleoside reverse transcriptase inhibitors decreases over time: evidence from the Delta trial.
    Antiviral therapy, 2008, Volume: 13, Issue:2

    Topics: Adult; Anti-HIV Agents; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Incidence; Male; Middle Aged; Peripheral Nervous System Diseases; Reverse Transcriptase Inhibitors; Risk Factors; Time Factors; Zalcitabine; Zidovudine

2008
Alternating and intermittent regimens of zidovudine and dideoxycytidine in patients with AIDS or AIDS-related complex.
    Annals of internal medicine, 1993, Mar-01, Volume: 118, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; CD4-Positive T-Lymphocytes; Drug Administration Schedule; Drug Therapy, Combination; Female; Hematologic Diseases; HIV Core Protein p24; Humans; Leukocyte Count; Male; Peripheral Nervous System Diseases; Weight Gain; Zalcitabine; Zidovudine

1993
Low dose methotrexate, bleomycin, doxorubicin, cyclophosphamide, vincristine, and dexamethasone with zalcitabine in patients with acquired immunodeficiency syndrome-related lymphoma. Effect on human immunodeficiency virus and serum interleukin-6 levels ov
    Cancer, 1996, Aug-01, Volume: 78, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bleomycin; Cyclophosphamide; Dexamethasone; Doxorubicin; HIV Core Protein p24; HIV-1; Humans; Interleukin-6; Leucovorin; Lymphoma, AIDS-Related; Male; Methotrexate; Middle Aged; Peripheral Nervous System Diseases; Remission Induction; Vincristine; Zalcitabine

1996
Acetyl-carnitine deficiency in AIDS patients with neurotoxicity on treatment with antiretroviral nucleoside analogues.
    AIDS (London, England), 1997, Volume: 11, Issue:2

    Topics: Acetylcarnitine; Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Axons; Cross-Sectional Studies; Didanosine; Female; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine

1997
Relation of peripheral neuropathy to HIV treatment in four randomized clinical trials including didanosine.
    Clinical therapeutics, 1999, Volume: 21, Issue:7

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Child, Preschool; Data Collection; Didanosine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Polypharmacy; Randomized Controlled Trials as Topic; Risk Factors; Time Factors; Zalcitabine; Zidovudine

1999

Other Studies

26 other study(ies) available for zalcitabine and Peripheral Nerve Diseases

ArticleYear
The isoform-specific functions of the c-Jun N-terminal kinase (JNK) in a mouse model of antiretroviral-induced painful peripheral neuropathy.
    European journal of pharmacology, 2020, Aug-05, Volume: 880

    Topics: Animals; Anti-Retroviral Agents; Disease Models, Animal; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mice, Knockout; Pain; Peripheral Nervous System Diseases; Zalcitabine

2020
PKC-mediated HuD-GAP43 pathway activation in a mouse model of antiretroviral painful neuropathy.
    Pharmacological research, 2014, Volume: 81

    Topics: Animals; Anti-HIV Agents; Brain; Disease Models, Animal; ELAV Proteins; ELAV-Like Protein 4; GAP-43 Protein; Hyperalgesia; Male; Mice; Pain; Peripheral Nervous System Diseases; Protein Kinase C; Reverse Transcriptase Inhibitors; Zalcitabine

2014
The RNA-binding protein HuD promotes spinal GAP43 overexpression in antiretroviral-induced neuropathy.
    Experimental neurology, 2014, Volume: 261

    Topics: Animals; Anti-Retroviral Agents; Cells, Cultured; Disease Models, Animal; ELAV Proteins; GAP-43 Protein; Gene Expression Regulation; Hyperalgesia; Male; Mice; Neurons; Oligodeoxyribonucleotides, Antisense; Pain; Peripheral Nervous System Diseases; Phosphopyruvate Hydratase; Protein Kinase C; Spinal Cord; Time Factors; Zalcitabine

2014
Spinal RyR2 pathway regulated by the RNA-binding protein HuD induces pain hypersensitivity in antiretroviral neuropathy.
    Experimental neurology, 2015, Volume: 267

    Topics: Analgesics, Non-Narcotic; Animals; Anti-HIV Agents; Apomorphine; Calcium Channel Blockers; Cell Line, Tumor; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; ELAV Proteins; ELAV-Like Protein 4; Exploratory Behavior; Gene Expression Regulation; Hyperalgesia; Male; Mice; Motor Activity; Neuroblastoma; Pain; Pain Threshold; Peripheral Nervous System Diseases; Ryanodine Receptor Calcium Release Channel; Spinal Cord; Zalcitabine

2015
Behavioral and electrophysiological abnormalities in two rat models of antiretroviral drug-induced neuropathy.
    Pain, 2015, Volume: 156, Issue:9

    Topics: Action Potentials; Animals; Anti-HIV Agents; Disease Models, Animal; Male; Nerve Fibers, Unmyelinated; Neural Conduction; Neurophysiology; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stavudine; Zalcitabine

2015
Comparison of dorsal root ganglion gene expression in rat models of traumatic and HIV-associated neuropathic pain.
    European journal of pain (London, England), 2009, Volume: 13, Issue:4

    Topics: Animals; Denervation; Disease Models, Animal; Ganglia, Spinal; Gene Expression Regulation; HIV Envelope Protein gp120; HIV Infections; Male; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Reverse Transcriptase Inhibitors; RNA, Messenger; Sensory Receptor Cells; Spinal Nerves; Transfection; Zalcitabine

2009
Alcohol consumption enhances antiretroviral painful peripheral neuropathy by mitochondrial mechanisms.
    The European journal of neuroscience, 2010, Volume: 32, Issue:5

    Topics: Alcoholic Neuropathy; Animals; Anti-HIV Agents; Disease Models, Animal; Drug Interactions; Electron Transport Chain Complex Proteins; Ethanol; Hyperalgesia; Male; Mitochondria; Oligodeoxyribonucleotides, Antisense; Peripheral Nervous System Diseases; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Zalcitabine

2010
The correlation between pain-related behaviour and spinal microgliosis in four distinct models of peripheral neuropathy.
    European journal of pain (London, England), 2012, Volume: 16, Issue:10

    Topics: Animals; Anti-HIV Agents; Behavior, Animal; Disease Models, Animal; Flow Cytometry; Gliosis; Herpes Zoster; Herpesvirus 3, Human; HIV Envelope Protein gp120; HIV Infections; Hyperalgesia; Immunohistochemistry; Male; Microglia; Peripheral Nerve Injuries; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Spinal Cord; Spinal Nerves; Zalcitabine

2012
Caspase signalling in neuropathic and inflammatory pain in the rat.
    The European journal of neuroscience, 2004, Volume: 20, Issue:11

    Topics: Animals; Caspase Inhibitors; Caspases; Ceramides; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Epinephrine; Hyperalgesia; Male; Neuralgia; Neurogenic Inflammation; Neuroprotective Agents; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Time Factors; Tumor Necrosis Factor-alpha; Vincristine; Zalcitabine

2004
Mechanically-evoked C-fiber activity in painful alcohol and AIDS therapy neuropathy in the rat.
    Molecular pain, 2007, Feb-23, Volume: 3

    Topics: Acquired Immunodeficiency Syndrome; Alcoholic Neuropathy; Animals; Comorbidity; Disease Models, Animal; Ethanol; Mechanics; Mechanotransduction, Cellular; Nerve Fibers, Unmyelinated; Pain; Peripheral Nervous System Diseases; Rats; Zalcitabine

2007
Characterization of rodent models of HIV-gp120 and anti-retroviral-associated neuropathic pain.
    Brain : a journal of neurology, 2007, Volume: 130, Issue:Pt 10

    Topics: Animals; Anti-Bacterial Agents; Anti-HIV Agents; Chemokine CCL2; Cold Temperature; Disease Models, Animal; Epidermis; Ganglia, Spinal; Gliosis; HIV Envelope Protein gp120; Hot Temperature; Hyperalgesia; Male; Minocycline; Motor Activity; Nerve Fibers; Nerve Tissue Proteins; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Wistar; Reverse Transcriptase Inhibitors; Zalcitabine

2007
Role of spinal serotonin 5-HT2A receptor in 2',3'-dideoxycytidine-induced neuropathic pain in the rat and the mouse.
    Pain, 2008, Volume: 137, Issue:1

    Topics: Animals; Ganglia, Spinal; Male; Mice; Mice, Knockout; Neuralgia; Nociceptors; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Species Specificity; Spinal Cord; Zalcitabine

2008
Risk factors for dideoxynucleoside-induced toxic neuropathy in patients with the human immunodeficiency virus infection.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Oct-01, Volume: 10, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Incidence; Male; Middle Aged; Peripheral Nervous System Diseases; Retrospective Studies; Risk Factors; Zalcitabine

1995
Exacerbation of peripheral neuropathy by lamivudine.
    Lancet (London, England), 1995, Feb-18, Volume: 345, Issue:8947

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Humans; Lamivudine; Male; Peripheral Nervous System Diseases; Zalcitabine

1995
Anti-human immunodeficiency virus type 1 therapy and peripheral neuropathy: prevention of 2',3'-dideoxycytidine toxicity in PC12 cells, a neuronal model, by uridine and pyruvate.
    Molecular pharmacology, 1993, Volume: 44, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Animals; Cell Survival; DNA Replication; DNA, Mitochondrial; HIV-1; Models, Biological; Neurons; PC12 Cells; Peripheral Nervous System Diseases; Pyruvates; Pyruvic Acid; Uridine; Zalcitabine

1993
2',3'-dideoxycytidine (ddC) toxic neuropathy: a study of 52 patients.
    Neurology, 1993, Volume: 43, Issue:2

    Topics: HIV Infections; Humans; Peripheral Nervous System Diseases; Time Factors; Zalcitabine

1993
Acoustic neuropathy associated with zalcitabine-induced peripheral neuropathy.
    AIDS (London, England), 1993, Volume: 7, Issue:6

    Topics: AIDS-Related Complex; Hearing Loss, Sensorineural; Humans; Hypesthesia; Male; Middle Aged; Peripheral Nervous System Diseases; Tinnitus; Vestibulocochlear Nerve Diseases; Zalcitabine

1993
[Zalcitabine].
    Enfermedades infecciosas y microbiologia clinica, 1997, Volume: 15, Issue:3

    Topics: Adult; Anti-HIV Agents; Digestive System Diseases; Drug Synergism; HIV; HIV Infections; Humans; Peripheral Nervous System Diseases; Retroviridae; Reverse Transcriptase Inhibitors; Zalcitabine

1997
New antiretroviral strategies: interview with Marcus Conant, M.D. Interview by John S. James.
    AIDS treatment news, 1995, Aug-04, Issue:no 228

    Topics: Antiviral Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Therapy, Combination; HIV; HIV Infections; Humans; Isoquinolines; Lamivudine; Peripheral Nervous System Diseases; Protease Inhibitors; Quinolines; Saquinavir; Stavudine; Zalcitabine; Zidovudine

1995
Mitochondrial alterations with mitochondrial DNA depletion in the nerves of AIDS patients with peripheral neuropathy induced by 2'3'-dideoxycytidine (ddC).
    Laboratory investigation; a journal of technical methods and pathology, 2001, Volume: 81, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; DNA, Mitochondrial; Humans; Microscopy, Electron; Middle Aged; Mitochondria; Peripheral Nervous System Diseases; Schwann Cells; Sural Nerve; Zalcitabine

2001
Peripheral neuropathy induced by 2',3'-dideoxycytidine. A rabbit model of 2',3'-dideoxycytidine neurotoxicity.
    Laboratory investigation; a journal of technical methods and pathology, 1992, Volume: 66, Issue:1

    Topics: Administration, Oral; Animals; Axons; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophysiology; Female; Male; Myelin Sheath; Neural Conduction; Paresis; Peripheral Nerves; Peripheral Nervous System Diseases; Rabbits; Sciatic Nerve; Zalcitabine

1992
Ultrastructure of peripheral neuropathy induced in rabbits by 2',3'-dideoxycytidine.
    Laboratory investigation; a journal of technical methods and pathology, 1992, Volume: 66, Issue:1

    Topics: Animals; Axons; Dose-Response Relationship, Drug; Edema; Microscopy, Electron; Myelin Proteins; Myelin Sheath; Peripheral Nerves; Peripheral Nervous System Diseases; Rabbits; Schwann Cells; Zalcitabine

1992
The PC12 cell as a model for studies of the mechanism of induction of peripheral neuropathy by anti-HIV-1 dideoxynucleoside analogs.
    Biochemical pharmacology, 1991, Jun-21, Volume: 42, Issue:1

    Topics: Animals; Axons; Bone Marrow; Cell Division; Cell Line, Transformed; Didanosine; Dideoxynucleosides; Dose-Response Relationship, Drug; Peripheral Nervous System Diseases; Stavudine; Tumor Cells, Cultured; Zalcitabine; Zidovudine

1991
Exacerbation of dideoxycytidine-induced neuropathy with dideoxyinosine.
    Journal of acquired immune deficiency syndromes, 1991, Volume: 4, Issue:5

    Topics: Adult; AIDS-Associated Nephropathy; Antiviral Agents; Didanosine; Drug Synergism; Drug Therapy, Combination; HIV Infections; Humans; Male; Peripheral Nervous System Diseases; Zalcitabine

1991
Reversible axonal neuropathy from the treatment of AIDS and related disorders with 2',3'-dideoxycytidine (ddC).
    Muscle & nerve, 1989, Volume: 12, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Axons; Dose-Response Relationship, Drug; Electromyography; Humans; Pain; Peripheral Nervous System Diseases; Zalcitabine

1989
Follow-up of neuropathy from 2',3'-dideoxycytidine.
    Lancet (London, England), 1988, Apr-09, Volume: 1, Issue:8589

    Topics: Deoxycytidine; Drug Administration Schedule; Follow-Up Studies; Humans; Peripheral Nervous System Diseases; Zalcitabine

1988