Page last updated: 2024-08-22

zalcitabine and HIV

zalcitabine has been researched along with HIV in 124 studies

*HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2. [MeSH]

Research

Studies (124)

Timeframe	Studies, this research(%)	All Research%
pre-1990	32 (25.81)	18.7374
1990's	84 (67.74)	18.2507
2000's	8 (6.45)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kalman, TI; Kerr, SG	1
Kaneko, C; Katagiri, N; Nomura, M; Sato, H; Tsuruo, T; Yusa, K	1
Montgomery, JA; Riggs, RM; Secrist, JA; Tiwari, KN	1
Aoki, S; Barchi, JJ; Driscoll, JS; Ford, H; Kelley, JA; Marquez, VE; Mitsuya, H; Shirasaka, T	1
Horwitz, JP; Kessel, D; Meltsner, BR; Palomino, E	1
Brankovan, V; Ghazzouli, I; Mansuri, MM; Martin, JC; Sterzycki, RZ	1
Hua, M; Vince, R	1
Augustyns, K; Balzarini, J; Blaton, N; De Clercq, E; De Ranter, C; Everaert, D; Janssen, G; Jie, L; Peeters, O; Van Aerschot, A	1
Broder, S; Driscoll, JS; Kim, CH; Marquez, VE; Mitsuya, H	1
Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H	1
Chen, MS; Gao, YS; Ghazzouli, I; Lin, TS; McLaren, C; Prusoff, WH	1
Greig, NH; Khamnei, S; Kinjo, J; Torrence, PF	1
Boulanger, WA; Chen, W; Cibulski, M; Flavin, MT; Flavin, TM; Greenwood, EM; Hughes, SH; Khilevich, A; Kucherenko, A; Lin, L; Pengsuparp, T; Pezzuto, JM; Rizzo, JD; Sheinkman, AK; Shone, RL; Vilaychack, V; Xu, ZQ	1
Austin, DJ; Cheng, YC; Chung, R; Dutschman, GE; Fu, L; Gullen, EA; Huang, ES; Lee, Y; Li, Y; Yeo, H; Zhu, JL	1
López Bernaldo de Quirós, JC	1
James, JS	2
Bates, M; Chappey, C; Clair, MS; Fisher, R; Lanier, ER; Parkin, N; Ross, L; Tisdale, M	1
Nelson, MR; Waters, L	1
Carvalho, AT; Fernandes, PA; Ramos, MJ	1
Connell, EV; Hsu, MC; Richman, DD	1
Kim, B; Loeb, LA	1
Domanski, MJ; Egan, D; Follmann, DA; Pizzo, PA; Scalise, PP; Sloas, MM; Tucker, EE	1
Frick, LW; Lambe, CU; Nelson, DJ; St John, L; Taylor, LC	1
Ellis, MN; Felgner, J; Felgner, PL; Gardner, MF; Hostetler, KY; Ricci, J; Richman, DD; Selleseth, DW; Sridhar, CN	1
Ashman, C; Barbeau, D; Cammack, N; Duchaine, J; Gagnon, L; Hamel, M; Hooker, E; Jutras, D; Nordstrom, PA; Tse, A	1
Richman, DD	1
Cohen, J	1
Beauchamp, D; Bergeron, MG; Désormeaux, A; Lessard, C; Makabi-Panzu, B; Perron, S; Poulin, L; Tremblay, M	1
Fischl, MA; Lai, S; Meng, TC; Resnick, L; Richman, DD; Spector, SA	1
Aubertin, AM; Bergogne, MC; Gosselin, G; Imbach, JL; Kirn, A; Mathé, C; Schinazi, RF; Sommadossi, JP	2
Lüthy, R	1
Lipsky, JJ	1
Bergé, P; Mildvan, D; Salgo, M; St Clair, M; Starrett, S	1
Magnuson, T; Mourton, T; Toltzis, P	1
Armbrecht, C; Hengels, KJ; Jablonowski, H; Manegold, C; Mauss, S; Szelenyi, H	1
Jablonowski, H	1
Baruch, A; Bassett, RL; Collier, AC; Coombs, RW; Corey, L; Facey, K; Friedman, HM; Hooper, C; Jones, M; McAuliffe, VJ; Merigan, TC; Reichman, RC; Schoenfeld, DA; Timpone, J; Whitacre, C	1
Boucher, CA; Cammack, N; Hill, A; Ingrand, D; Loveday, C; Robert, C; Weber, J	1
Cheng, YC; Dutschman, GE; Gullen, E; Lin, TS; Liu, MC; Luo, MZ; Zhu, YL	1
Buckheit, R; Decker, W; Elder, C; Grever, M; Hollingshead, M; Malspeis, L; Mayo, J; Roberson, J	1
Bartlett, JA; Benoit, SL; Ehmann, WC; Fallon, MA; Johnson, VA; Quinn, JB; Rubin, M; Self, PL; Sepulveda, GE; Tsoukas, C	1
Rowe, PM	1
Rosenthal, C	1
Ho, DD	1
Skowron, G	1
Farrant, RD; Frick, LW; Lindon, JC; Sanderson, PN; Shockcor, JP; Sweatman, BC; Wurm, RM	1
Collins, DO; Sakamoto, A	1
Bloch, J; Chavance, M	1
Cammack, N; Dissanayeke, SR; Duncan, IB; Gilbert, SM; Moffatt, AR; Race, E; Rose, JS; Sheldon, JG; Sitbon, G	1
Balfour, HH; Erice, A; Fischl, MA; Henry, K; Hirsch, MS; Kahn, JO; Kenton, A; Kmack, A; Liou, SH; Martinez, A; Phair, J; Tierney, C	1
Chen, SH; Cheng, YC; Doyle, TW; Dutschman, GE; Gullen, EA; King, I; Lin, S; Spinka, T	1
Aquilina, C; Bonnet, E; Izopet, J; Marchou, B; Massip, P; Pasquier, C; Puel, J; Sailler, L; Sandres, K	1
Phillips, L	1
Boschini, A; Calista, D	1
Conant, M	1
Mascolini, M	2
Gilden, D	1
Chang, HE	1
Coombs, R; Cotton, D; Hammer, S; Saag, M; van der Horst, C	1
Smart, T	1
Torres, G	2
Doepel, L; Folkers, G	1
Cannon, D; Furman, PA; Lloyd, RM; Mathis, R; McMillan, A; Peck, A; Schinazi, RF; Sommadossi, JP; St Clair, M; Wilson, J	1
Gallo, JM; Mehta, M; Qian, MX; Swagler, AR; Vishwanathan, CT	1
Kahn, J	1
Balzarini, J; Bergamini, A; Calio, R; De Clercq, E; Milanese, G; Pauwels, R; Perno, CF; Rocchi, G; Yarchoan, R	1
Peck, A; Schinazi, RF; Sommadossi, JP	1
Watson, AJ; Wilburn, LM	1
Moosmann, EB	1
Broder, S; Caliò, R; Cooney, DA; Foli, A; Gao, WY; Hao, Z; Hartman, NR; Johns, DG; Perno, CF; Yarchoan, R	1
Boehme, RE; Cameron, JM; Figueiredo, HT; Gray, NM; Hart, GJ; Orr, DC; Penn, CR	1
Rousseau, F; Sereni, D	1
Cameron, JM; Coates, JA; Inggall, HJ; Pearson, BA; Penn, CR; Storer, R; Williamson, C	1
Chimirri, A; Grasso, S; Monforte, AM; Monforte, P; Zappalà, M	1
Gallo, JM; Qian, MX; Swagler, AR	1
Broder, S	2
Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R	1
Broder, S; Mitsuya, H; Perno, CF; Pluda, JM; Yarchoan, R	1
Van Aerschot, A	1
Mahler, W	2
Chen, CH; Cheng, YC; Vazquez-Padua, M	1
Balzarini, J; De Clercq, E; Good, SS; Gosselin, G; Imbach, JL; Puech, F; Rideout, JL	1
Pizzo, PA	1
Broder, S; Mitsuya, H; Yarchoan, R	1
Beard, AR; Butler, PI; Mann, J; Partlett, NK	1
Cheng, YC; Starnes, MC	1
Broder, S; DeVico, AL; Di Marzo Veronese, F; Jarrett, RF; Johns, DG; Matsukura, M; Mitsuya, H; Reitz, MS; Sarngadharan, MG	1
Baba, M; Balzarini, J; De Clercq, E; Desmyter, J; Herdewijn, P; Pauwels, R; Schols, D; Snoeck, R	1
Jeffries, DJ	1
Darby, G; Larder, BA; Richman, DD	1
Fine, RL; Friedmann, RM; Gartner, S; Popovic, M; Skaleric, U; Szebeni, J; Wahl, LM; Wahl, SM; Weinstein, JN	1
Hotta, T; Inoue, T; Itoh, T; Nagai, Y; Ogura, M; Saitoh, H; Saneyoshi, M; Tomoda, Y; Tsushita, K; Yoshida, S	1
Hsia, K; Ripley, D; Spector, SA	1
Bianchi, M; Magnani, M; Rossi, L; Stocchi, V	1
Blair, PC; Fort, MM; Fuchs, BA; Germolec, DR; Luster, MI; McCay, JA; Munson, AE; Thompson, M; Tomaszewski, JE; White, KL	1
Balzarini, J; De Clercq, E; Johns, DG; Matthes, E; Meeus, P	1
Chen, CH; Cheng, YC	1
Agrawal, KC; Beckman, BS; Gogu, SR	1
Balzarini, J; De Clercq, E; Desmyter, J; Goubau, P; Herdewijn, P; Pauwels, R; Vandeputte, M; Vanderhaeghe, H	1
Carson, DA; Kornbluth, RS; Richman, DD	1
Balzarini, J; Broder, S; Cooney, DA; Cupp, JE; Dalal, M; DeClercq, E; Johns, DG; Kang, GJ	1
Baba, M; Balzarini, J; Broder, S; de Clercq, E; Herdewijn, P; Johns, DG; Pauwels, R	1
Birnbaum, GI; Lin, TS; Prusoff, WH	1
Broder, S; Mitsuya, H	1
Baba, M; Balzarini, J; De Clerq, E; Herdewijn, P; Pauwels, R	1
Chou, TC; Coleman, LA; Durno, AG; Hirsch, MS; Kaplan, JC; Paradis, TJ; Schooley, RT; Vogt, MW	1
Cooney, DA; Gartner, S; Gerrard, TL; Hao, Z; Hartman, NR; Johns, DG; Perno, CF; Popovic, M; Wilson, YA; Yarchoan, R	1
Brownell, J; Daluge, S; Hua, M; Kiser, R; Lavelle, GC; Lee, FC; Qualls, J; Shannon, WM; Vince, R; Weislow, OS	1
Allain, JP; Dubinsky, R; Fischl, MA; Klecker, RW; McAtee, N; McNeely, MC; Perno, CF; Thomas, RV; Wills, RJ; Yarchoan, R	1
Balzarini, J; Broder, S; Cooney, DA; Dalal, M; De Clercq, E; Herdewijn, P; Johns, DG; Kang, GJ; Pauwels, R	1
Chen, MS; Kinney-Thomas, E; Lin, TS; Prusoff, WH; Schinazi, RF	1
Hamamoto, Y; Matsuda, A; Matsui, T; Nakashima, H; Ueda, T; Yamamoto, N	1

Reviews

15 review(s) available for zalcitabine and HIV

Article	Year
[Tenofovir DF in rescue regimens]. Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 8 Topics: Adenine; Anti-HIV Agents; Antimetabolites; Clinical Trials, Phase III as Topic; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV; HIV Infections; HIV Reverse Transcriptase; Humans; Multicenter Studies as Topic; Mutation; Organophosphonates; Randomized Controlled Trials as Topic; Retrospective Studies; Reverse Transcriptase Inhibitors; Salvage Therapy; Selection, Genetic; Tenofovir; Thymidine; Treatment Failure; Viral Load; Zalcitabine	2008
New drugs. HIV medicine, 2005, Volume: 6, Issue:4 Topics: Anti-HIV Agents; Benzophenones; Cytidine Triphosphate; Darunavir; Deoxycytidine; Emtricitabine; HIV; HIV Fusion Inhibitors; HIV Reverse Transcriptase; Humans; Imidazoles; Nitriles; Protease Inhibitors; Pyridazines; Pyridines; Pyrimidines; Pyrones; Reverse Transcriptase Inhibitors; Sulfonamides; Sulfur Compounds; Zalcitabine	2005
Resistance, drug failure, and disease progression. AIDS research and human retroviruses, 1994, Volume: 10, Issue:8 Topics: Antiviral Agents; Disease Progression; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Nevirapine; Pyridines; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine	1994
[Antiretroviral therapy. Current status and perspectives]. Der Internist, 1994, Volume: 35, Issue:10 Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Stavudine; Zalcitabine; Zidovudine	1994
Zalcitabine and didanosine. Lancet (London, England), 1993, Jan-02, Volume: 341, Issue:8836 Topics: Adult; Antiviral Agents; Child; Didanosine; DNA Replication; DNA, Viral; Drug Interactions; HIV; HIV Infections; Humans; Virus Replication; Zalcitabine	1993
[Therapy of HIV infection with nucleoside analogs]. Zeitschrift fur Gastroenterologie, 1993, Volume: 31 Suppl 5 Topics: Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Nucleosides; Zalcitabine; Zidovudine	1993
Studies of zidovudine in combination with didanosine and zalcitabine. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Volume: 10 Suppl 1 Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Disease Progression; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Reverse Transcriptase Inhibitors; Safety; Zalcitabine; Zidovudine	1995
ddC (zalcitabine). Advances in experimental medicine and biology, 1996, Volume: 394 Topics: Antiviral Agents; Drug Therapy, Combination; HIV; HIV Infections; Humans; Zalcitabine; Zidovudine	1996
Anti-human immunodeficiency virus therapeutics: now and the future. Seminars in liver disease, 1992, Volume: 12, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Didanosine; Dideoxynucleosides; HIV; HIV-1; Humans; Trichosanthin; Zalcitabine; Zidovudine	1992
[Treatments of human immunodeficiency virus infection. Current developments]. Annales de medecine interne, 1991, Volume: 142, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Didanosine; HIV; HIV Infections; Humans; Zalcitabine; Zidovudine	1991
Pharmacodynamics of 2',3'-dideoxycytidine: an inhibitor of human immunodeficiency virus. The American journal of medicine, 1990, May-21, Volume: 88, Issue:5B Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; DNA Polymerase II; HIV; Humans; Male; Phosphorylation; RNA-Directed DNA Polymerase; Zalcitabine	1990
Targeted therapy of human immunodeficiency virus-related disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1991, Volume: 5, Issue:10 Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine	1991
Anti-retroviral therapy of human immunodeficiency virus infection: current strategies and challenges for the future. Blood, 1991, Aug-15, Volume: 78, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Resistance; HIV; HIV Infections; Humans; Lymphoma, Non-Hodgkin; Retroviridae; Reverse Transcriptase Inhibitors; T-Lymphocytes, Helper-Inducer; Virus Replication; Zalcitabine; Zidovudine	1991
Treatment of human immunodeficiency virus-infected infants and young children with dideoxynucleosides. The American journal of medicine, 1990, May-21, Volume: 88, Issue:5B Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Child; Child, Preschool; Dideoxynucleosides; Drug Tolerance; HIV; HIV Infections; Humans; Infant; Zalcitabine; Zidovudine	1990
Targets for antiviral therapy of human immunodeficiency virus infection. The Journal of infection, 1989, Volume: 18 Suppl 1 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Dideoxynucleosides; Drug Therapy, Combination; Genes, Regulator; HIV; Humans; Reverse Transcriptase Inhibitors; Virus Replication; Zalcitabine; Zidovudine	1989

Trials

12 trial(s) available for zalcitabine and HIV

Article	Year
Resistance, drug failure, and disease progression. AIDS research and human retroviruses, 1994, Volume: 10, Issue:8 Topics: Antiviral Agents; Disease Progression; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Nevirapine; Pyridines; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine	1994
Resistance to AZT and ddC during long-term combination therapy in patients with advanced infection with human immunodeficiency virus. Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:2 Topics: CD4-Positive T-Lymphocytes; Drug Resistance, Microbial; Drug Therapy, Combination; HeLa Cells; HIV; HIV Infections; Humans; Leukocyte Count; Time Factors; Zalcitabine; Zidovudine	1994
Treatment of human immunodeficiency virus infection with saquinavir, zidovudine, and zalcitabine. AIDS Clinical Trials Group. The New England journal of medicine, 1996, Apr-18, Volume: 334, Issue:16 Topics: Adult; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Male; Quinolines; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Treatment Outcome; Zalcitabine; Zidovudine	1996
Phase I/II study of 3TC (lamivudine) in HIV-positive, asymptomatic or mild AIDS-related complex patients: sustained reduction in viral markers. The Lamivudine European HIV Working Group. AIDS (London, England), 1995, Volume: 9, Issue:12 Topics: Adult; AIDS-Related Complex; Antigen-Antibody Complex; Antiviral Agents; Dose-Response Relationship, Drug; HIV; HIV Core Protein p24; HIV Infections; HIV Seropositivity; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Viremia; Zalcitabine	1995
Lamivudine plus zidovudine compared with zalcitabine plus zidovudine in patients with HIV infection. A randomized, double-blind, placebo-controlled trial. North American HIV Working Party. Annals of internal medicine, 1996, Aug-01, Volume: 125, Issue:3 Topics: Adult; Antiviral Agents; beta 2-Microglobulin; Biopterins; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV; HIV Core Protein p24; HIV Infections; Humans; Lamivudine; Male; Neopterin; Polymerase Chain Reaction; RNA, Viral; Severity of Illness Index; Time Factors; Treatment Outcome; Zalcitabine; Zidovudine	1996
Hplc-nmr identification of the human urinary metabolites of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analogue active against human immunodeficiency virus (HIV). Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:2 Topics: Antiviral Agents; Biotransformation; Chromatography, High Pressure Liquid; Emtricitabine; Glucuronates; HIV; Humans; Magnetic Resonance Spectroscopy; Spectrophotometry, Ultraviolet; Stereoisomerism; Sulfoxides; Zalcitabine	1996
Correlation of response to treatment and HIV genotypic changes during phase III trials with saquinavir and reverse transcriptase inhibitor combination therapy. AIDS (London, England), 1998, Aug-20, Volume: 12, Issue:12 Topics: Amino Acid Sequence; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV; HIV Infections; HIV Protease; HIV Protease Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Phenotype; Proviruses; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Treatment Outcome; Zalcitabine; Zidovudine	1998
A randomized, controlled, double-blind study comparing the survival benefit of four different reverse transcriptase inhibitor therapies (three-drug, two-drug, and alternating drug) for the treatment of advanced AIDS. AIDS Clinical Trial Group 193A Study T Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Dec-01, Volume: 19, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease-Free Survival; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV; Humans; Male; Nevirapine; Placebos; Reverse Transcriptase Inhibitors; RNA, Viral; Survival Rate; Time Factors; Zalcitabine; Zidovudine	1998
Intermittent selection pressure with zidovudine plus zalcitabine treatment reduces the emergence in vivo of zidovudine resistance HIV mutations. Journal of medical virology, 1999, Volume: 57, Issue:2 Topics: Adult; Amino Acid Substitution; Anti-HIV Agents; CD4 Lymphocyte Count; DNA Mutational Analysis; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Reverse Transcriptase; Humans; Male; Mutation; RNA, Viral; Zalcitabine; Zidovudine	1999
Major study shows AZT monotherapy inferior. AIDS treatment news, 1995, Sep-29, Issue:no 231 Topics: CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine	1995
Dideoxycytidine (ddC): a potent antiretroviral agent for human immunodeficiency virus infection. An introduction. The American journal of medicine, 1990, May-21, Volume: 88, Issue:5B Topics: Clinical Trials as Topic; Drug Therapy, Combination; HIV; HIV Infections; Humans; Zalcitabine; Zidovudine	1990
New treatment being tested against AIDS and ARC. Oncology (Williston Park, N.Y.), 1987, Volume: 1, Issue:7 Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Clinical Trials as Topic; HIV; Humans; Virus Replication; Zalcitabine	1987

Other Studies

98 other study(ies) available for zalcitabine and HIV

Article	Year
Highly water-soluble lipophilic prodrugs of the anti-HIV nucleoside analogue 2',3'-dideoxycytidine and its 3'-fluoro derivative. Journal of medicinal chemistry, 1992, May-29, Volume: 35, Issue:11 Topics: Antiviral Agents; Chemical Phenomena; Chemistry, Physical; Drug Stability; HIV; Hydrolysis; Lipids; Prodrugs; Solubility; Structure-Activity Relationship; Water; Zalcitabine	1992
Synthesis and anti-HIV activity of 9-[c-4,t-5-bis(hydroxymethyl)cyclopent-2-en-r-1-yl]-9H-adenine. Journal of medicinal chemistry, 1992, May-15, Volume: 35, Issue:10 Topics: Adenine; Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Stereoisomerism	1992
Synthesis and anti-HIV activity of 4'-thio-2',3'-dideoxynucleosides. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Antiviral Agents; Dideoxynucleosides; HIV	1992
Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs. Journal of medicinal chemistry, 1991, Volume: 34, Issue:5 Topics: Adenosine Deaminase; Antiviral Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV; Kinetics; Prodrugs; Structure-Activity Relationship	1991
Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders. Journal of medicinal chemistry, 1990, Volume: 33, Issue:1 Topics: AIDS Dementia Complex; Animals; Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Chemistry, Physical; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Kinetics; Molecular Structure; Phosphorylation; Pyrimidine Nucleosides; Rabbits; Stavudine; T-Lymphocytes; Thymidine Kinase; Thymus Gland; Zidovudine	1990
Synthesis and anti-HIV activity of several 2'-fluoro-containing pyrimidine nucleosides. Journal of medicinal chemistry, 1990, Volume: 33, Issue:8 Topics: Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Survival; Chemical Phenomena; Chemistry; Fluorine; Gene Products, gag; HIV; HIV Antigens; HIV Core Protein p24; Humans; Macrophages; Molecular Structure; Monocytes; Pyrimidine Nucleosides; T-Lymphocytes; Tumor Cells, Cultured; Viral Core Proteins; Zalcitabine; Zidovudine	1990
Synthesis and anti-HIV activity of carbocyclic 2',3'-didehydro-2',3'-dideoxy 2,6-disubstituted purine nucleosides. Journal of medicinal chemistry, 1990, Volume: 33, Issue:1 Topics: Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Dideoxyadenosine; Dideoxynucleosides; HIV; Leukemia P388; Molecular Structure; Purine Nucleosides; Structure-Activity Relationship; Tumor Cells, Cultured; Virus Replication; Zidovudine	1990
Synthesis and anti-HIV evaluation of 2',3'-dideoxyribo-5-chloropyrimidine analogues: reduced toxicity of 5-chlorinated 2',3'-dideoxynucleosides. Journal of medicinal chemistry, 1990, Volume: 33, Issue:6 Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; HIV; Humans; Molecular Conformation; X-Ray Diffraction	1990
Potential anti-AIDS drugs. 2',3'-Dideoxycytidine analogues. Journal of medicinal chemistry, 1987, Volume: 30, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Cell Line; Chemical Phenomena; Chemistry; Deoxycytidine; HIV; Structure-Activity Relationship; T-Lymphocytes, Helper-Inducer; Zalcitabine	1987
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents. Journal of medicinal chemistry, 1987, Volume: 30, Issue:8 Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication	1987
Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses. Journal of medicinal chemistry, 1987, Volume: 30, Issue:2 Topics: Antiviral Agents; Cell Line; HIV; Indicators and Reagents; Magnetic Resonance Spectroscopy; Moloney murine leukemia virus; Pyrimidine Nucleosides; Spectrophotometry; Structure-Activity Relationship	1987
Synthesis and pharmacokinetics of a dihydropyridine chemical delivery system for the antiimmunodeficiency virus agent dideoxycytidine. Journal of medicinal chemistry, 1993, Mar-05, Volume: 36, Issue:5 Topics: Animals; Biotransformation; Brain; Cytosine; Cytosol; Dihydropyridines; Drug Carriers; HIV; HIV-1; Hydrolysis; Kinetics; Male; Oxidation-Reduction; Prodrugs; Rats; Rats, Wistar; Zalcitabine	1993
Synthesis, chromatographic resolution, and anti-human immunodeficiency virus activity of (+/-)-calanolide A and its enantiomers. Journal of medicinal chemistry, 1996, Mar-15, Volume: 39, Issue:6 Topics: Antiviral Agents; Chromatography, High Pressure Liquid; Coumarins; HIV; HIV Reverse Transcriptase; Nucleic Acid Synthesis Inhibitors; Pyranocoumarins; RNA-Directed DNA Polymerase; Stereoisomerism	1996
Synthesis and antiviral activity of helioxanthin analogues. Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2 Topics: Antiviral Agents; Benzofurans; Cytomegalovirus; Dioxoles; Hepacivirus; Hepatitis B virus; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 4, Human; HIV; Lactones; Lignans; Naphthalenes; Structure-Activity Relationship	2005
Antiretroviral pipeline: new-drug reports from retroviruses conference. AIDS treatment news, 2004, Feb-27, Issue:398 Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Cytidine Triphosphate; Drug Resistance, Viral; HIV; HIV Fusion Inhibitors; Membrane Fusion; Zalcitabine	2004
Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance. AIDS (London, England), 2004, Aug-20, Volume: 18, Issue:12 Topics: Adenine; Algorithms; Anti-HIV Agents; Databases, Genetic; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV; HIV Infections; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zalcitabine; Zidovudine	2004
Insights on resistance to reverse transcriptase: the different patterns of interaction of the nucleoside reverse transcriptase inhibitors in the deoxyribonucleotide triphosphate binding site relative to the normal substrate. Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26 Topics: Binding Sites; Computer Simulation; Deoxyribonucleotides; Drug Resistance, Multiple, Viral; HIV; HIV Reverse Transcriptase; Humans; Molecular Conformation; Nucleosides; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Zalcitabine	2006
Combinative interactions of a human immunodeficiency virus (HIV) Tat antagonist with HIV reverse transcriptase inhibitors and an HIV protease inhibitor. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:2 Topics: Antiviral Agents; Benzodiazepines; Didanosine; Drug Synergism; Gene Products, tat; HeLa Cells; HIV; HIV Protease Inhibitors; Humans; Isoquinolines; Nevirapine; Pyridines; Pyrroles; Quinolines; Reverse Transcriptase Inhibitors; Saquinavir; tat Gene Products, Human Immunodeficiency Virus; Zalcitabine; Zidovudine	1994
A screen in Escherichia coli for nucleoside analogs that target human immunodeficiency virus (HIV) reverse transcriptase: coexpression of HIV reverse transcriptase and herpes simplex virus thymidine kinase. Journal of virology, 1995, Volume: 69, Issue:10 Topics: Antiviral Agents; Cloning, Molecular; Cytarabine; DNA Polymerase I; Drug Evaluation, Preclinical; Escherichia coli; Gene Expression; HIV; Kinetics; Phosphorylation; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Simplexvirus; Thymidine Kinase; Zalcitabine; Zidovudine	1995
Effect of zidovudine and didanosine treatment on heart function in children infected with human immunodeficiency virus. The Journal of pediatrics, 1995, Volume: 127, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Cardiomyopathies; CD4 Lymphocyte Count; Child, Preschool; Didanosine; Dose-Response Relationship, Drug; Echocardiography; Female; Heart; HIV; Humans; Infant; Infant, Newborn; Male; Medical Records; Retrospective Studies; Severity of Illness Index; Zalcitabine; Zidovudine	1995
Pharmacokinetics, oral bioavailability, and metabolism in mice and cynomolgus monkeys of (2'R,5'S-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, an agent active against human immunodeficiency virus and human hepatitis B virus. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:12 Topics: Administration, Oral; Animals; Antiviral Agents; Biological Availability; Emtricitabine; Hepatitis B virus; HIV; Macaca fascicularis; Male; Mice; Mice, Inbred ICR; Species Specificity; Zalcitabine	1994
Phosphatidylazidothymidine and phosphatidyl-ddC: assessment of uptake in mouse lymphoid tissues and antiviral activities in human immunodeficiency virus-infected cells and in Rauscher leukemia virus-infected mice. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:12 Topics: Animals; Female; HIV; Lymphoid Tissue; Mice; Mice, Inbred BALB C; Phospholipids; Prodrugs; Rauscher Virus; Zalcitabine; Zidovudine	1994
Immunomodulatory and antiviral activities of 2',3'-dideoxy-beta-L-cytidine and 2',3'-dideoxy-beta-L-5-fluorocytidine. Immunopharmacology and immunotoxicology, 1995, Volume: 17, Issue:1 Topics: Animals; Antiviral Agents; Cell Cycle; Cell Line; Chlorocebus aethiops; Hepatitis B virus; HIV; Humans; Immunosuppressive Agents; Lymphocyte Activation; Mice; Simplexvirus; T-Lymphocytes; Tumor Cells, Cultured; Vero Cells; Zalcitabine	1995
AIDS mood upbeat--for a change. Science (New York, N.Y.), 1995, Feb-17, Volume: 267, Issue:5200 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; Gene Products, nef; Herpesviridae; HIV; Humans; Lamivudine; nef Gene Products, Human Immunodeficiency Virus; Sarcoma, Kaposi; Simian Immunodeficiency Virus; Virus Replication; Zalcitabine; Zidovudine	1995
Comparison of cellular accumulation, tissue distribution, and anti-HIV activity of free and liposomal 2',3'-dideoxycytidine. AIDS research and human retroviruses, 1994, Volume: 10, Issue:11 Topics: Animals; Biological Transport, Active; Cell Line; Drug Carriers; Female; HIV; Humans; Liposomes; Macrophages; Mononuclear Phagocyte System; Rats; Rats, Sprague-Dawley; Tissue Distribution; Zalcitabine	1994
Enantiomeric 2',3'-dideoxycytidine derivatives are potent human immunodeficiency virus inhibitors in cell cultures. Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1994, Volume: 317, Issue:1 Topics: Cells, Cultured; HIV; HIV-1; HIV-2; Molecular Conformation; Stereoisomerism; Zalcitabine	1994
Anti-human immunodeficiency virus activities of the beta-L enantiomer of 2',3'-dideoxycytidine and its 5-fluoro derivative in vitro. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:6 Topics: Antiviral Agents; Bone Marrow; Cell Line; Drug Resistance; HIV; Humans; Stereoisomerism; Zalcitabine	1994
Prophylactic zalcitabine and interferon-alpha for a large-bore needlestick exposure to human immunodeficiency virus. Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:4 Topics: Adult; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Interferon alpha-2; Interferon-alpha; Needlestick Injuries; Recombinant Proteins; Zalcitabine; Zidovudine	1994
Comparative embryonic cytotoxicity of antiretroviral nucleosides. The Journal of infectious diseases, 1994, Volume: 169, Issue:5 Topics: Animals; Antiviral Agents; Culture Techniques; Didanosine; Embryo, Mammalian; HIV; Mice; Nucleosides; Stavudine; Zalcitabine; Zidovudine	1994
Design and synthesis of 2',3'-dideoxy-2',3'-didehydro-beta-L-cytidine (beta-L-d4C) and 2',3'-dideoxy 2',3'-didehydro-beta-L-5-fluorocytidine (beta-L-Fd4C), two exceptionally potent inhibitors of human hepatitis B virus (HBV) and potent inhibitors of human Journal of medicinal chemistry, 1996, Apr-26, Volume: 39, Issue:9 Topics: Antiviral Agents; Drug Design; Hepatitis B virus; HIV; Humans; Zalcitabine	1996
In vivo drug screening applications of HIV-infected cells cultivated within hollow fibers in two physiologic compartments of mice. Antiviral research, 1995, Volume: 28, Issue:3 Topics: Animals; Antiviral Agents; Cells, Cultured; Drug Evaluation, Preclinical; HIV; HIV Core Protein p24; Humans; Mice; Mice, SCID; RNA-Directed DNA Polymerase; Virus Cultivation; Virus Replication; Zalcitabine; Zidovudine	1995
New guidelines set for occupational HIV exposure. Lancet (London, England), 1996, Jul-06, Volume: 348, Issue:9019 Topics: Accidents, Occupational; Antiviral Agents; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Practice Guidelines as Topic; Pyridines; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine	1996
[Resistance and combined use of anti-HIV drugs]. Revista da Sociedade Brasileira de Medicina Tropical, 1995, Volume: 28 Suppl 2 Topics: Antiviral Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Mutation; Zalcitabine; Zidovudine	1995
Therapy of HIV infections: problems and prospects. Bulletin of the New York Academy of Medicine, 1996,Summer, Volume: 73, Issue:1 Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Stavudine; Urban Health; Zalcitabine; Zidovudine	1996
[HIV: to administer protease inhibitors early]. Deutsche medizinische Wochenschrift (1946), 1996, Dec-06, Volume: 121, Issue:49 Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Time Factors; Zalcitabine; Zidovudine	1996
[Zalcitabine]. Enfermedades infecciosas y microbiologia clinica, 1997, Volume: 15, Issue:3 Topics: Adult; Anti-HIV Agents; Digestive System Diseases; Drug Synergism; HIV; HIV Infections; Humans; Peripheral Nervous System Diseases; Retroviridae; Reverse Transcriptase Inhibitors; Zalcitabine	1997
Cure or control of HIV/AIDS? Medical hypotheses, 1997, Volume: 48, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Models, Biological; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine	1997
A mixed model for repeated dilution assays. Biometrics, 1998, Volume: 54, Issue:2 Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Models, Statistical; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Reproducibility of Results; Viral Load; Zalcitabine; Zidovudine	1998
Synthesis and comparative evaluation of two antiviral agents: beta-L-Fd4C and beta-D-Fd4C. Bioorganic & medicinal chemistry letters, 1998, Nov-17, Volume: 8, Issue:22 Topics: Animals; Antiviral Agents; Hepatitis B virus; HIV; Mice; Rats; Stereoisomerism; Zalcitabine	1998
Antiretroviral drugs: new agents, new combinations line up against HIV. Hospital technology series, 1996, Volume: 15, Issue:1 Topics: Antiviral Agents; Australia; Didanosine; Drug Therapy, Combination; Europe; HIV; HIV Infections; Humans; Lamivudine; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Ritonavir; Thiazoles; United States; Valine; Zalcitabine; Zidovudine	1996
Cutaneous side effects induced by indinavir. European journal of dermatology : EJD, 2000, Volume: 10, Issue:4 Topics: Adult; Alopecia; Didanosine; Drug Eruptions; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lipodystrophy; Male; Middle Aged; Pruritus; Pyoderma Gangrenosum; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Scalp Dermatoses; Skin; Stavudine; Zalcitabine; Zidovudine	2000
New antiretroviral strategies: interview with Marcus Conant, M.D. Interview by John S. James. AIDS treatment news, 1995, Aug-04, Issue:no 228 Topics: Antiviral Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Therapy, Combination; HIV; HIV Infections; Humans; Isoquinolines; Lamivudine; Peripheral Nervous System Diseases; Protease Inhibitors; Quinolines; Saquinavir; Stavudine; Zalcitabine; Zidovudine	1995
A Lisbon traviata. Are clinicians ready to sing addio to monotherapy and libiamo to combinations? Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:8 Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; HIV; HIV Infections; Humans; Hydroxyurea; Indinavir; Interleukin-2; Lamivudine; Mutation; Pyridines; RNA, Viral; Zalcitabine; Zidovudine	1995
Roaches of inner space. GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:10 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Lamivudine; Mutation; T-Lymphocytes, Cytotoxic; Virulence; Virus Replication; Zalcitabine; Zidovudine	1995
Conference looks at HIV drug resistance. GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:9 Topics: Antiviral Agents; Carbamates; CD4 Lymphocyte Count; Drug Resistance, Microbial; Furans; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Sulfonamides; Thiazoles; Valine; Viremia; Zalcitabine; Zidovudine	1995
Closing the circle on HIV--or not. Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:9 Topics: Antiviral Agents; Biomarkers; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Interleukin-2; Nelfinavir; Prognosis; RNA, Viral; Zalcitabine; Zidovudine	1995
To treat or not to treat--approaches to antiretroviral therapy. Interview by Anthony J. Japour. AIDS clinical care, 1996, Volume: 8, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Didanosine; Drug Therapy, Combination; HIV; Humans; Lamivudine; Practice Patterns, Physicians'; RNA, Viral; Zalcitabine; Zidovudine	1996
Nipping HIV in the bud. GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:8 Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Stavudine; Thiazoles; Valine; Virus Replication; Zalcitabine; Zidovudine	1996
3TC treatment may slow HIV mutations, development of drug resistance. NIAID AIDS agenda, 1996 Topics: Drug Resistance, Microbial; HIV; HIV Infections; Humans; Lamivudine; Mutation; Zalcitabine	1996
Outdated yet out-of-reach: AIDS society treatment guidelines at the International Conference. GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:9 Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Decision Making; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Practice Guidelines as Topic; Zalcitabine; Zidovudine	1996
NIAID researchers present new findings at retrovirus meeting. National Institute of Allergy and Infectious Diseases. NIAID AIDS agenda, 1997 Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Chemokines; Clinical Trials as Topic; Clone Cells; Dendritic Cells; Didanosine; Disease Progression; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Interleukin-10; Killer Cells, Natural; Lamivudine; Male; Nevirapine; Pyridines; Receptors, Cytokine; Reverse Transcriptase Inhibitors; Ritonavir; Virus Replication; Zalcitabine; Zidovudine	1997
Hydroxyurea, a potential new anti-HIV agent. GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:1 Topics: Didanosine; DNA Replication; Drug Therapy, Combination; HIV; HIV Infections; Humans; Hydroxyurea; Leukocytes, Mononuclear; Virus Replication; Zalcitabine; Zidovudine	1995
Zalcitabine (Hivid). Research initiative, treatment action : RITA, 2000, Volume: 6, Issue:1 Topics: Drug Resistance, Microbial; HIV; HIV Infections; Humans; Practice Guidelines as Topic; Reverse Transcriptase Inhibitors; Zalcitabine	2000
Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11 Topics: Antiviral Agents; Emtricitabine; HIV; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stereoisomerism; Zalcitabine; Zidovudine	1992
Pharmacokinetic evaluation of drug interactions with anti-human immunotrophic virus (HIV) Drugs. III. 2',3'-Dideoxycytidine (ddC) and zidovudine in monkeys. Pharmaceutical research, 1992, Volume: 9, Issue:2 Topics: Animals; Antiviral Agents; Drug Interactions; HIV; Macaca fascicularis; Male; Zalcitabine; Zidovudine	1992
Different pattern of activity of inhibitors of the human immunodeficiency virus in lymphocytes and monocyte/macrophages. Antiviral research, 1992, Volume: 17, Issue:4 Topics: Adenine; Antibodies, Viral; Antiviral Agents; Benzodiazepines; CD4 Antigens; Cytokines; Didanosine; Doxorubicin; Drug Interactions; HIV; HIV Infections; Humans; Imidazoles; Leukocytes, Mononuclear; Lymphocytes; Macrophages; Monocytes; Organ Specificity; Organophosphonates; Zalcitabine; Zidovudine	1992
Substrate specificity of Escherichia coli thymidine phosphorylase for pyrimidine nucleosides with anti-human immunodeficiency virus activity. Biochemical pharmacology, 1992, Jul-22, Volume: 44, Issue:2 Topics: Antiviral Agents; Biological Availability; Deoxyuridine; Dideoxynucleosides; Emtricitabine; Escherichia coli; HIV; Pyrimidine Nucleosides; Stavudine; Substrate Specificity; Thymidine Phosphorylase; Zalcitabine	1992
Inhibition of HIV infection of resting peripheral blood lymphocytes by nucleosides. AIDS research and human retroviruses, 1992, Volume: 8, Issue:7 Topics: Base Sequence; Cells, Cultured; Didanosine; DNA, Viral; HIV; Humans; Lymphocyte Activation; Molecular Sequence Data; Polymerase Chain Reaction; Proviruses; T-Lymphocytes; Virus Replication; Zalcitabine; Zidovudine	1992
[Another AIDS drug. Azidothymidine--dideoxycytidine]. Fortschritte der Medizin, 1992, Jun-30, Volume: 110, Issue:18 Topics: Acquired Immunodeficiency Syndrome; CD4-Positive T-Lymphocytes; HIV; Humans; Leukocyte Count; Virus Replication; Zalcitabine; Zidovudine	1992
Effects of bone marrow stimulatory cytokines on human immunodeficiency virus replication and the antiviral activity of dideoxynucleosides in cultures of monocyte/macrophages. Blood, 1992, Aug-15, Volume: 80, Issue:4 Topics: Antiviral Agents; Bone Marrow; Cells, Cultured; Cytokines; Didanosine; Dideoxynucleosides; Erythropoietin; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; HIV; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Virus Replication; Zalcitabine; Zidovudine	1992
Effects of (-)-2'-deoxy-3'-thiacytidine (3TC) 5'-triphosphate on human immunodeficiency virus reverse transcriptase and mammalian DNA polymerases alpha, beta, and gamma. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:8 Topics: Antiviral Agents; Base Sequence; DNA Polymerase I; DNA Polymerase II; DNA Polymerase III; DNA-Directed DNA Polymerase; HIV; Kinetics; Lamivudine; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Nucleotides; Peptide Chain Termination, Translational; Polyribonucleotides; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zalcitabine	1992
Carbovir: the (-) enantiomer is a potent and selective antiviral agent against human immunodeficiency virus in vitro. Antiviral research, 1991, Volume: 15, Issue:2 Topics: CD4-Positive T-Lymphocytes; Cell Line; Cell Survival; Dideoxynucleosides; Giant Cells; HIV; Humans; Viral Core Proteins; Virus Replication; Zalcitabine; Zidovudine	1991
Anti-HIV agents. I: Synthesis and in vitro anti-HIV evaluation of novel 1H,3H-thiazolo[3,4-a]benzimidazoles. Farmaco (Societa chimica italiana : 1989), 1991, Volume: 46, Issue:6 Topics: Antiviral Agents; Benzimidazoles; CD4-Positive T-Lymphocytes; Cell Line; Cytopathogenic Effect, Viral; HIV; Humans; Thiazoles; Zalcitabine; Zidovudine	1991
Pharmacokinetics of anti-HIV nucleosides in microswine. The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:12 Topics: Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Didanosine; Half-Life; HIV; Male; Nucleosides; Swine; Swine, Miniature; Zalcitabine; Zidovudine	1991
[Synthesis and anti-retroviral activity of various new 2',3'-dideoxynucleoside analogs]. Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1991, Volume: 53, Issue:4 Topics: Dideoxynucleosides; HIV; Humans; Reverse Transcriptase Inhibitors; Zalcitabine	1991
[AIDS: initial results of combination therapy. AIDS and ARC--alternating or intermittent medication]. Fortschritte der Medizin, 1991, Jan-15, Volume: 109, Issue:1 Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; CD4 Antigens; Combined Modality Therapy; HIV; Humans; Immunotherapy, Adoptive; Interferon Type I; Recombinant Proteins; Zalcitabine; Zidovudine	1991
Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity. Molecular pharmacology, 1991, Volume: 39, Issue:5 Topics: Antiviral Agents; Cell Line; Cytarabine; Didanosine; Dideoxynucleosides; DNA, Mitochondrial; HIV; Humans; Lymphocyte Activation; Nucleosides; Stavudine; T-Lymphocytes; Zalcitabine; Zidovudine	1991
Synthesis and biological evaluation of dinucleoside methylphosphonates of 3'-azido-3'-deoxythymidine and 2', 3'-dideoxycytidine. Antiviral research, 1990, Volume: 14, Issue:1 Topics: Animals; Antineoplastic Agents; Deoxycytosine Nucleotides; Drug Evaluation, Preclinical; HIV; Hydrolysis; Mice; Mice, Inbred C3H; Moloney murine sarcoma virus; Thymine Nucleotides; Tumor Cells, Cultured; Virus Replication; Zalcitabine; Zidovudine	1990
Dideoxycytidine (ddC): a potent antiretroviral agent for human immunodeficiency virus infection. A symposium. February 3, 1990, San Francisco, California. Proceedings. The American journal of medicine, 1990, May-21, Volume: 88, Issue:5B Topics: Animals; HIV; HIV Infections; Humans; Zalcitabine	1990
Strategies for the combination therapy of HIV infection. Journal of acquired immune deficiency syndromes, 1990, Volume: 3 Suppl 2 Topics: Acyclovir; Antiviral Agents; Drug Therapy, Combination; HIV; HIV Infections; Humans; Virus Replication; Zalcitabine; Zidovudine	1990
Synthesis of 2',3'-dideoxy-2',3'-alpha-methanocytidine. Carbohydrate research, 1990, Sep-19, Volume: 205 Topics: Antiviral Agents; HIV; Magnetic Resonance Spectroscopy; Molecular Structure; Zalcitabine	1990
Cellular metabolism of 2',3'-dideoxycytidine, a compound active against human immunodeficiency virus in vitro. The Journal of biological chemistry, 1987, Jan-25, Volume: 262, Issue:3 Topics: Cell Line; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA; HIV; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Phosphorylation; RNA; T-Lymphocytes; Zalcitabine	1987
Long-term inhibition of human T-lymphotropic virus type III/lymphadenopathy-associated virus (human immunodeficiency virus) DNA synthesis and RNA expression in T cells protected by 2',3'-dideoxynucleosides in vitro. Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:7 Topics: Antiviral Agents; Base Sequence; Cell Line; Deoxyadenosines; Deoxycytidine; Dideoxyadenosine; DNA Replication; HIV; Humans; RNA-Directed DNA Polymerase; RNA, Messenger; T-Lymphocytes; Transcription, Genetic; Zalcitabine	1987
Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds. Journal of virological methods, 1988, Volume: 20, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cell Line, Transformed; Colorimetry; Cytopathogenic Effect, Viral; Dextran Sulfate; Dextrans; Dideoxynucleosides; Drug Evaluation, Preclinical; Heparin; HIV; Humans; Tetrazolium Salts; Thiazoles; Zalcitabine; Zidovudine	1988
HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy. Science (New York, N.Y.), 1989, Mar-31, Volume: 243, Issue:4899 Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Dideoxynucleosides; Drug Resistance; Foscarnet; HeLa Cells; HIV; HIV Core Protein p24; Humans; Microbial Sensitivity Tests; Phosphonoacetic Acid; Retroviridae Proteins; Reverse Transcriptase Inhibitors; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine	1989
Dipyridamole potentiates the inhibition by 3'-azido-3'-deoxythymidine and other dideoxynucleosides of human immunodeficiency virus replication in monocyte-macrophages. Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:10 Topics: Antiviral Agents; Biological Transport; Bone Marrow; Bone Marrow Cells; Cell Survival; Dideoxynucleosides; Dipyridamole; Drug Synergism; HIV; Humans; In Vitro Techniques; Interferon Type I; Macrophages; Monocytes; Virus Replication; Zalcitabine; Zidovudine	1989
In vitro bone marrow toxicity of nucleoside analogs against human immunodeficiency virus. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:4 Topics: Antiviral Agents; Bone Marrow Diseases; Colony-Forming Units Assay; Dideoxynucleosides; HIV; Humans; Nucleosides; Zalcitabine; Zidovudine	1989
Human immunodeficiency virus inhibition is prolonged by 3'-azido-3'-deoxythymidine alternating with 2',3'-dideoxycytidine compared with 3'-azido-3'-deoxythymidine alone. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:6 Topics: Antiviral Agents; Cells, Cultured; Dideoxynucleosides; DNA, Viral; HIV; Humans; Time Factors; Virus Replication; Zalcitabine; Zidovudine	1989
Human red blood cells as bioreactors for the release of 2',3'-dideoxycytidine, an inhibitor of HIV infectivity. Biochemical and biophysical research communications, 1989, Oct-16, Volume: 164, Issue:1 Topics: Drug Administration Routes; Erythrocytes; HIV; Humans; Phosphorylation; Zalcitabine	1989
[AIDS: small, life-prolonging steps. Antiviral therapy is more efficient--a decrease in side effects]. Fortschritte der Medizin, 1989, Sep-10, Volume: 107, Issue:26 Topics: Acquired Immunodeficiency Syndrome; HIV; Humans; Zalcitabine; Zidovudine	1989
A comparison of three nucleoside analogs with anti-retroviral activity on immune and hematopoietic functions in mice: in vitro toxicity to precursor cells and microstromal environment. Toxicology and applied pharmacology, 1989, Volume: 101, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Animals; Antigen-Antibody Reactions; Antiviral Agents; Bone Marrow; Dideoxyadenosine; Female; Hematopoiesis; HIV; Immunity, Cellular; Macrophages; Mice; Mice, Inbred C57BL; Spleen; Stem Cells; T-Lymphocytes; Virus Replication; Zalcitabine; Zidovudine	1989
The antiretroviral and cytostatic activity, and metabolism of 3'-azido-2',3'-dideoxythymidine, 3'-fluoro-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly cell type-dependent. Advances in experimental medicine and biology, 1989, Volume: 253B Topics: Antiviral Agents; Cell Division; Cell Line; Dideoxynucleosides; HIV; Humans; Virus Replication; Zalcitabine; Zidovudine	1989
Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2',3'-dideoxycytidine. The Journal of biological chemistry, 1989, Jul-15, Volume: 264, Issue:20 Topics: Antiviral Agents; Cell Line; Cell Survival; Deoxyribonuclease BamHI; Dideoxynucleosides; DNA, Mitochondrial; Electrophoresis, Agar Gel; HIV; Lactates; Lactic Acid; Zalcitabine	1989
Anti-HIV drugs: comparative toxicities in murine fetal liver and bone marrow erythroid progenitor cells. Life sciences, 1989, Volume: 45, Issue:4 Topics: Animals; Antiviral Agents; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Dideoxynucleosides; Fetus; Hematopoietic Stem Cells; HIV; Liver; Mice; Ribavirin; Zalcitabine; Zidovudine	1989
Sensitive and rapid assay on MT-4 cells for detection of antiviral compounds against the AIDS virus. Journal of virological methods, 1987, Volume: 16, Issue:3 Topics: Antigens, Viral; Antiviral Agents; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Deoxycytidine; Flow Cytometry; Fluorescent Antibody Technique; HIV; Humans; Thymidine; Zalcitabine; Zidovudine	1987
Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages. The Journal of experimental medicine, 1987, Oct-01, Volume: 166, Issue:4 Topics: Adenosine Kinase; Cell Line; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Dideoxyadenosine; HIV; Humans; Macrophages; Phosphorylation; T-Lymphocytes; Thymidine; Thymidine Kinase; Uridine Kinase; Virus Replication; Zalcitabine; Zidovudine	1987
2',3'-Dideoxycytidine: regulation of its metabolism and anti-retroviral potency by natural pyrimidine nucleosides and by inhibitors of pyrimidine nucleotide synthesis. Molecular pharmacology, 1987, Volume: 32, Issue:6 Topics: Animals; Antiviral Agents; Deoxycytidine; Deoxycytosine Nucleotides; HIV; Humans; Leukemia L1210; Mice; Phosphorylation; Pyrimidine Nucleosides; Pyrimidine Nucleotides; Pyrimidines; Thymidine; Tritium; Tumor Cells, Cultured; Zalcitabine	1987
The in vitro and in vivo anti-retrovirus activity, and intracellular metabolism of 3'-azido-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly dependent on the cell species. Biochemical pharmacology, 1988, Mar-01, Volume: 37, Issue:5 Topics: Animals; Antiviral Agents; Cell Line; Deoxycytidine; HIV; Humans; Mice; Mice, Inbred C3H; Moloney murine sarcoma virus; Retroviridae; Thymidine; Zalcitabine; Zidovudine	1988
Unusual structural features of 2',3'-dideoxycytidine, an inhibitor of the HIV (AIDS) virus. Biochemical and biophysical research communications, 1988, Feb-29, Volume: 151, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Chemical Phenomena; Chemistry; Crystallography; Deoxycytidine; HIV; Models, Molecular; Molecular Conformation; Zalcitabine	1988
Inhibition of infectivity and replication of HIV-2 and SIV in helper T-cells by 2',3'-dideoxynucleosides in vitro. AIDS research and human retroviruses, 1988, Volume: 4, Issue:2 Topics: Cytopathogenic Effect, Viral; Deoxyadenosines; Deoxycytidine; Dideoxyadenosine; HIV; In Vitro Techniques; Nucleosides; Retroviridae; T-Lymphocytes, Helper-Inducer; Thymidine; Viral Proteins; Virus Replication; Zalcitabine; Zidovudine	1988
Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues. Biochemical pharmacology, 1988, Jul-15, Volume: 37, Issue:14 Topics: Animals; Antimetabolites; Antiviral Agents; Cell Division; Deoxycytidine; Deoxycytidine Kinase; Dideoxynucleosides; DNA; HIV; Kinetics; Mice; Phosphorylation; Pyrimidine Nucleosides; Retroviridae; Thymidine; Thymidine Kinase; Zalcitabine	1988
Synergistic interaction of 2',3'-dideoxycytidine and recombinant interferon-alpha-A on replication of human immunodeficiency virus type 1. The Journal of infectious diseases, 1988, Volume: 158, Issue:2 Topics: Antiviral Agents; Cell Line; Deoxycytidine; Drug Synergism; HIV; Humans; Interferon Type I; Leukocytes; Recombinant Proteins; Thymidine; Virus Replication; Zalcitabine; Zidovudine	1988
Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides. The Journal of experimental medicine, 1988, Sep-01, Volume: 168, Issue:3 Topics: Antiviral Agents; Deoxycytidine Kinase; Dideoxyadenosine; Dideoxynucleosides; HIV; Humans; In Vitro Techniques; Macrophages; Monocytes; Phosphorylation; Thymidine Kinase; Time Factors; Virus Replication; Zalcitabine; Zidovudine	1988
Potent and selective activity of a new carbocyclic nucleoside analog (carbovir: NSC 614846) against human immunodeficiency virus in vitro. Biochemical and biophysical research communications, 1988, Oct-31, Volume: 156, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Molecular Structure; Structure-Activity Relationship; Virus Replication; Zalcitabine; Zidovudine	1988
Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT). Lancet (London, England), 1988, Jan-16, Volume: 1, Issue:8577 Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Deoxycytidine; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; HIV; Humans; Male; Middle Aged; Thymidine; Zalcitabine; Zidovudine	1988
Potent and selective anti-HTLV-III/LAV activity of 2',3'-dideoxycytidinene, the 2',3'-unsaturated derivative of 2',3'-dideoxycytidine. Biochemical and biophysical research communications, 1986, Oct-30, Volume: 140, Issue:2 Topics: Animals; Antigens, Viral; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Deoxycytidine; Deoxycytidine Kinase; HIV; Humans; Mice; Zalcitabine	1986
Antiviral activity of 2',3'-dideoxycytidin-2'-ene (2',3'-dideoxy-2',3'-didehydrocytidine) against human immunodeficiency virus in vitro. Biochemical pharmacology, 1987, Feb-01, Volume: 36, Issue:3 Topics: Antiviral Agents; Deoxycytidine; Fluorescence; HIV; Humans; In Vitro Techniques; Monocytes; Thymidine; Zalcitabine; Zidovudine	1987
Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:6 Topics: Antigens, Viral; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Thymidine; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine	1987