zalcitabine has been researched along with Acquired Immune Deficiency Syndrome in 237 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (14.77) | 18.7374 |
| 1990's | 193 (81.43) | 18.2507 |
| 2000's | 9 (3.80) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Clercq, E | 1 |
| Broder, S; Driscoll, JS; Kim, CH; Marquez, VE; Mitsuya, H | 1 |
| Buckheit, RW; Flavin, MT; Khilevich, A; Lin, L; Rizzo, JD; Stup, TL; Xu, ZQ; Zembower, DE | 1 |
| Bettendorf, DM; Christopherson, C; D'Aquila, RT; Hammer, SM; Katzenstein, DA; Lathey, JL; Tierney, C | 1 |
| Baker, SG; Fitzmaurice, GM; Freedman, LS; Kramer, BS | 1 |
| Chen, X; Levine, JD | 1 |
| Tastemain, C | 1 |
| Carr, A; Cooper, DA; Loewenthal, M | 1 |
| Leibowitch, J; Liotta, DC; Mathez, D; Schinazi, RF | 1 |
| Mitsuya, H | 2 |
| Chong, KT; Hinshaw, RR; Pagano, PJ | 1 |
| Britton, S; Julander, I | 1 |
| Beardsley, T | 2 |
| Cameron, J; Cammack, N; Cooley, TP; Gu, Z; Hirst, HM; McCaffrey, R; Montaner, JS; Ruedy, J; Salomon, H; Wainberg, MA | 1 |
| Clifford, DB; Fichtenbaum, CJ; Powderly, WG | 1 |
| Stephenson, J | 1 |
| Dalakas, MC; Lewis, W | 1 |
| Domanski, MJ; Egan, D; Follmann, DA; Pizzo, PA; Scalise, PP; Sloas, MM; Tucker, EE | 1 |
| Kamali, F | 1 |
| Lissen, E | 1 |
| Khoo, SH; Wilkins, EG | 1 |
| Cooley, TP; Hirst, HM; Montaner, JS; Pluda, JM; Quinn, JB; Reinhalter, NE; Ruedy, J; Shay, LE; Vicary, CA; Warthan, SN | 1 |
| Böttger, S | 1 |
| Berry, S; Bozzette, SA; Duan, N; Kanouse, DE | 1 |
| Dall, L; Tal, A | 1 |
| Krasinski, K | 1 |
| Abrams, DI | 1 |
| Dormont, J | 1 |
| Cupler, EJ; Dalakas, MC | 1 |
| Cohen, J | 2 |
| Abrams, DI; Crane, LR; Goldman, AI; Grodesky, M; Kornegay, S; Korvick, JA; Launer, C; Muth, K; Neaton, JD; Wakefield, S | 1 |
| Stretcher, B | 1 |
| Picard, O | 1 |
| Craib, KJ; Hogg, RS; Montaner, JS; O'Shaughnessy, MV; Schechter, MT; Strathdee, SA | 1 |
| Roberts, J | 1 |
| Aziz, N; Cumberland, WG; Fahey, JL; Liu, M; Merigan, T; Skowron, G | 1 |
| Allan, JD; Arduino, JM; Collier, AC; Feinberg, JE; Fischl, MA; Goldsmith, JC; Powderly, WG; Stanley, K; Stein, DS | 1 |
| Fong, IW | 1 |
| Portet-Brunet, L | 1 |
| Antoniskis, D; Arezzo, J; Bigley, J; Bozzette, SA; Fischl, MA; Gelb, LD; Gocke, DJ; Grieco, MH; Hirsch, MS; Hyslop, NE; Leedom, JM; Lim, L; LoFaro, ML; McKinley, GF; Merigan, TC; Murphy, RL; Pettinelli, CB; Pottage, JC; Powderly, WG; Ray, G; Reed, N; Richman, DD; Schaumburg, HH; Simon, G; Skowron, G; Soo, W; Spector, SA; Sperber, SJ; Uttamchandani, RB; Zachary, J | 1 |
| Anderson, TD; Feldman, D | 1 |
| Dalakas, MC; Jay, C; Ropka, M | 1 |
| Arduino, JM; Chung, R; Crumpacker, CS; Hammer, SM; Japour, AJ; Lane, J; Mayers, DL; McLeod, GX; Reichman, R; Wagner, KF | 1 |
| Dubin, DT; Farnham, AE; Fitzgibbon, JE; Kim, H; Sperber, SJ | 1 |
| Hobbs, GA; Keilbaugh, SA; Simpson, MV | 1 |
| Baranowski, E; Kaulen, P; Pham, DT; Wollensak, J | 1 |
| Anderson, BD; Broder, S; Husson, RN; Kojima, E; Mitsuya, H; O'Brien, MC; Shimada, T; Shirasaka, T; Yarchoan, R | 1 |
| Dionne, G; Gao, Q; Gu, Z; Hiscott, J; Wainberg, MA | 1 |
| Edelman, K; Hooker, M; Muirhead, GJ; Rousseau, FS; Sereni, D; Williams, PE | 1 |
| Broder, S; Gao, WY; Johns, DG; Mitsuya, H; Shirasaka, T | 1 |
| Butler, KM; Husson, RN; Mitsuya, H; Pizzo, PA; Shirasaka, T | 1 |
| Arts, EJ; Boulerice, F; Geleziunas, R; Goldman, H; Wainberg, MA | 1 |
| Aponte-Cipriani, SL; Teplitz, C; Yancovitz, S | 1 |
| Brawley, O; Broder, S; Cohen, RB; Nguyen, BY; Pluda, JM; Shay, LE; Venzon, DJ; Whitcup, SM; Wyvill, KM; Yarchoan, R | 1 |
| Moosmann, EB | 2 |
| Clumeck, N | 1 |
| MacIlwain, C | 1 |
| Holazo, AA; Limjuco, R; Massarella, JW; Min, B; Nazareno, LA; Passe, S; Twardy, SK | 1 |
| Pinching, AJ | 2 |
| Boswell, W; Buckley, J; Espina, B; Gill, PS; Levine, AM; Nathwani, B; Parker, J; Rasheed, S; Stain, S; Tulpule, A | 1 |
| Boucher, CA; De Boer, RJ | 1 |
| Abrams, D; Collins, G; Crane, L; Hodges, JS; Loveless, MO; Markowitz, N; Pettinelli, C; Reves, R; Saravolatz, LD; Stein, DS; Thompson, M; Winslow, DL | 1 |
| Corey, L; Holmes, KK | 1 |
| Ambetima, N; Blanquet, D; Hallard, M; Mathé, G; Morette, C; Orbach-Arbouys, S; Pontiggia, P; Triana, K | 1 |
| Gries, JM; Jacobson, M; Sheiner, LB; Troconiz, IF; Verotta, D | 1 |
| Zaretsky, MD | 1 |
| De Simone, C; Famularo, G; Longo, A; Marcellini, S; Moretti, S; Santini, G; Trinchieri, V; Tzantzoglou, S | 1 |
| Millard, PS | 1 |
| Bechtel, LM; Starich, GH; Whitfield, RM | 1 |
| Gatell-Artigas, JM | 1 |
| Caruz, A; Leal, M; Lissen, E; Rey, C | 1 |
| Hirschel, B; Rutschmann, O | 1 |
| Heins, JR | 1 |
| Bakshi, SS; Boone, G; Britto, P; Capparelli, E; Fowler, MG; Frank, Y; Jimenez, E; Mofenson, L; Pahwa, SG; Rasheed, S; Salgo, M; Schoenfeld, D; Yogev, R; Zimmer, B | 1 |
| Bürgisser, P; Meylan, PR; Pagani, JL; Spertini, F; Weyrich-Suter, C | 1 |
| Bennett, LL; Parker, WB; Shaddix, SC; Vince, R | 1 |
| al-Attar, I; Burchett, SK; Chatis, P; Fuchs, D; Kornegay, J; McIntosh, K; Orav, J; Wachter, H; Zaknun, D; Zaknun, J | 1 |
| Collins, DO; Sakamoto, A | 1 |
| Baker, J; Böhnlein, E; Junker, U; Kalfoglou, CS; Kaneshima, H; Veres, G | 1 |
| Blanco, JR; Ibarra, V; Oteo, JA | 1 |
| Adams, JM; DeRemer, M; DiFrancesco, R; Grasela, TH; Hewitt, RG; Morse, GD; Shelton, MJ | 1 |
| DeMasi, R; Hill, AM; Montaner, JS | 1 |
| Baldeweg, T; Catalan, J; Gazzard, BG | 1 |
| Balfour, HH; Erice, A; Fischl, MA; Henry, K; Hirsch, MS; Kahn, JO; Kenton, A; Kmack, A; Liou, SH; Martinez, A; Phair, J; Tierney, C | 1 |
| Collier, AC; Coombs, RW; Efron, B; Lawrence, J; Merigan, TC; Schapiro, JM; Speck, R; Winters, MA | 1 |
| Blaschke, TF; Girard, P; Kastrissios, H; Katzenstein, D; Sheiner, LB; Suárez, JR | 1 |
| Blaschke, TF; Hammer, S; Kastrissios, H; Katzenstein, D; Suárez, JR | 1 |
| Andersson, F; Hatziandreu, EJ; Oleksy, I; Shakespeare, A; Simpson, K; Tosteson, AN | 1 |
| Armitage, P | 1 |
| Djomand, G; Lackritz, EM; Mbidde, E; Weidle, PJ | 1 |
| Clotet, B; Gómez-Cano, M; Leal, M; Pérez-Olmeda, M; Puig, T; Rey, C; Rubio, A; Ruiz, L; Soriano, V; Xaus, N; Zamora, L | 1 |
| Briones, C; Soriano, V | 1 |
| Berger, AR; Eng, KT; Liu, ES; Silverman, MS | 1 |
| Betensky, RA; Rabinowitz, D; Tsiatis, AA | 1 |
| Bagnarelli, P; Chauvin, JP; Clementi, M; De Truchis, P; Gorin, I; Katlama, C; Leibowitch, J; Mathez, D; Mills, R; Pialoux, G; Rode, R; Saimot, G; Tubiana, P | 1 |
| Cabrera, C; Clotet, B; Ibáñez, A; Morales, MA; Puig, T; Romeu, J; Ruiz, L; Sirera, G | 1 |
| Anderson, KS; Feng, JY; Johnson, AA; Johnson, KA | 1 |
| Mascolini, M | 1 |
| Poscher, M | 1 |
| King, E | 1 |
| Levin, J | 1 |
| Baker, R | 1 |
| Gilden, D | 1 |
| Torres, G | 2 |
| Smart, T | 2 |
| Coombs, R; Cotton, D; Hammer, S; Saag, M; van der Horst, C | 1 |
| James, JS | 2 |
| Alcorn, K | 1 |
| Folkers, G | 1 |
| Dalakas, MC; Leon-Monzon, M; Semino-Mora, C | 1 |
| Blanquet, D; Hage, F; Hallard, M; Mathe, G; Morette, C; Pontiggia, P | 1 |
| Gao, Q; Gu, Z; Li, X; Parniak, MA; Wainberg, MA | 1 |
| Bolton, V; Carlson, JR; Cohen, SH; Dickover, RE; Donovan, RM; Goldstein, E; Huth, RG; Liu, GZ | 1 |
| Molina, JM | 1 |
| Caliò, R; Perno, CF | 1 |
| Dubin, DT; Fitzgibbon, JE; Gocke, DJ; Haberzettl, CA; Howell, RM; Sperber, SJ | 1 |
| Boehme, RE; Cameron, JM; Cammack, N; Coates, JA; Marr, CL; Penn, CR; Reid, PJ; Rouse, P | 1 |
| Amari, JV; Brown, PR; Pivarnik, PE; Sehgal, RK; Turcotte, JG | 1 |
| Johnson, VA | 1 |
| Kahn, J | 1 |
| Hammer, SM; McLeod, GX | 2 |
| Saag, MS | 1 |
| Skowron, G | 1 |
| Meyer, C | 1 |
| Garfunkel, AA; Glick, M | 1 |
| Broder, S; Pluda, JM; Yarchoan, R | 1 |
| Bennett, SM; Jajoo, HK; Kornhauser, DM | 1 |
| Töglhofer, W | 1 |
| Rousseau, F; Sereni, D | 1 |
| Gao, Q; Li, XG; Parniak, MA; Rooke, R; Soudeyns, H; Tremblay, M; Wainberg, MA; Yao, XJ | 1 |
| Goldsmith, MF | 1 |
| Nowak, R | 1 |
| Fischl, MA | 1 |
| Anastasi, JK; Rivera, JL | 1 |
| Alkan, M | 1 |
| Broder, S | 1 |
| Horgan, J | 1 |
| Goto, H; Kimura, S; Oka, S; Shimada, K | 1 |
| Mitsuya, H; Pluda, JM; Yarchoan, R | 1 |
| Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R | 1 |
| Broder, S; Mitsuya, H; Perno, CF; Pluda, JM; Yarchoan, R | 1 |
| Fernández-Cruz, E | 1 |
| Cersosimo, RJ; Matthews, SJ; Spivack, ML | 1 |
| Schaefer, E | 1 |
| Merigan, TC | 1 |
| Mahler, W | 2 |
| Balis, FM; Hawkins, ME; Pizzo, PA; Poplack, DG | 1 |
| Cotton, P | 2 |
| Dunton, AW; Fukuda, EK; Gustavson, LE; Rubio, FA | 1 |
| Merigan, TC; Skowron, G | 2 |
| Pizzo, PA | 1 |
| Fischl, MA; Meng, TC; Richman, DD | 1 |
| Betageri, GV; Black, CD; Gartner, S; Parker, RJ; Popovic, M; Szebeni, J; Wahl, LM; Wahl, SM; Weinstein, JN | 1 |
| Coulston, AM; Dybevik, K; McCorkindale, C; Sucher, KP | 1 |
| Balis, F; Brouwers, E; Butler, K; Eddy, J; Einloth, M; Falloon, J; Hawkins, M; Husson, R; Jarosinski, P; Pizzo, PA | 1 |
| McGowan, J; Merigan, T; Sherwin, S | 1 |
| Hoth, D | 1 |
| Baba, M; Balzarini, J; De Clercq, E; Desmyter, J; Herdewijn, P; Pauwels, R; Schols, D; Snoeck, R | 1 |
| Jeffries, DJ | 1 |
| Darby, G; Larder, BA; Richman, DD | 1 |
| Bozzette, SA; Fischl, M; Hirsch, M; Merigan, TC; Pettinelli, C; Richman, D; Schooley, R; Skowron, G; Soo, W; Uttamchandani, R | 1 |
| Ganser, A; Greher, J; Hoelzer, D; Staszewski, S; Völkers, B | 1 |
| Hill, DL; Hoover, EA; Mullins, JI; Perigo, NA; Quackenbush, SL; Strobel, JD; Zeidner, NS | 1 |
| de Noronha, F; Postie, L; Roneker, C; Tavares, L | 1 |
| Hill, DL; Hoover, EA; Mullins, JI; Perigo, NA; Strobel, JD; Zeidner, NS | 1 |
| Fukushima, S; Kawaguchi, T; Mishima, M; Nakano, M; Ohmura, M | 1 |
| Blair, PC; Fort, MM; Fuchs, BA; Germolec, DR; Luster, MI; McCay, JA; Munson, AE; Thompson, M; Tomaszewski, JE; White, KL | 1 |
| Bianchi, M; Magnani, M; Rossi, L; Stocchi, V | 1 |
| Broder, S; Lawley, TJ; McNeely, MC; Yarchoan, R | 1 |
| Broder, S; Dalakas, M; Dubinsky, RM; Yarchoan, R | 1 |
| Fridland, A; Johns, DG; Johnson, MA | 1 |
| Miller, JL | 1 |
| Brady, RO; O'Neill, RR | 1 |
| Birnbaum, GI; Lin, TS; Prusoff, WH | 1 |
| Balfour, HH; Henry, K; Thurn, JR | 1 |
| Coons, T; McCartan, K; Rockwell, S; Ullman, B | 1 |
| Brownell, J; Daluge, S; Hua, M; Kiser, R; Lavelle, GC; Lee, FC; Qualls, J; Shannon, WM; Vince, R; Weislow, OS | 1 |
| Caiazzo, T; Donahue, R; Groopman, J; Johnson, M; Molina, JM | 1 |
| Stingl, G; Wolff, K | 1 |
| Crews, T; Fukuda, EK; Garland, WA; Rubio, FR | 1 |
| Walz, B | 1 |
| Richman, DD | 1 |
| Broder, S; Collins, JM; Klecker, RW; McAtee, N; Myers, CE; Thomas, R; Yarchoan, RC | 1 |
| Allain, JP; Dubinsky, R; Fischl, MA; Klecker, RW; McAtee, N; McNeely, MC; Perno, CF; Thomas, RV; Wills, RJ; Yarchoan, R | 1 |
| Offerhaus, L | 1 |
38 review(s) available for zalcitabine and Acquired Immune Deficiency Syndrome
| Article | Year |
|---|---|
Chemotherapeutic approaches to the treatment of the acquired immune deficiency syndrome (AIDS).
Topics: Acquired Immunodeficiency Syndrome; Adsorption; Antibodies, Viral; Antigens, Viral; Aurintricarboxylic Acid; Deltaretrovirus; Deoxycytidine; Foscarnet; Genes, Viral; Glycoproteins; Humans; Interferons; Male; Phosphonoacetic Acid; Retroviridae Infections; Reverse Transcriptase Inhibitors; Ribavirin; RNA, Viral; Suramin; Thymidine; Transcription, Genetic; Viral Proteins; Virus Replication; Zalcitabine; Zidovudine | 1986 |
Update on reverse transcriptase inhibitors in HIV disease.
Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Didanosine; Humans; Prognosis; Reverse Transcriptase Inhibitors; Risk Factors; Zalcitabine; Zidovudine | 1993 |
Mitochondrial toxicity of antiviral drugs.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Arabinofuranosyluracil; Didanosine; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Humans; Mitochondria; Zalcitabine; Zidovudine | 1995 |
Clinical pharmacology of zidovudine and other 2',3'-dideoxynucleoside analogues.
Topics: Acquired Immunodeficiency Syndrome; Adult; Child; Didanosine; Dideoxynucleosides; Drug Interactions; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Interferons; Needlestick Injuries; Sarcoma, Kaposi; Zalcitabine; Zidovudine | 1993 |
[Anti-HIV therapy (1987-1994): from nothing to confusion].
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Time Factors; Zalcitabine; Zidovudine | 1995 |
Controversies in anti-retroviral therapy of adults.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; AIDS-Related Complex; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Drug Tolerance; HIV Infections; HIV-1; Humans; Zalcitabine; Zidovudine | 1995 |
Antiretroviral therapy for children.
Topics: Acquired Immunodeficiency Syndrome; Adult; Child; Clinical Trials as Topic; Controlled Clinical Trials as Topic; Didanosine; DNA, Viral; Drug Resistance, Microbial; HIV-1; Humans; Immunity, Cellular; Virus Replication; Zalcitabine; Zidovudine | 1994 |
Future treatment strategies in HIV infection.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Antiviral Agents; Biomarkers; CD4 Lymphocyte Count; Didanosine; Forecasting; HIV Infections; Humans; Zalcitabine; Zidovudine | 1994 |
Management of antiretroviral drug therapy in human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Didanosine; HIV-1; Humans; Retroviridae Infections; Zalcitabine; Zidovudine | 1994 |
Antiretroviral therapy for human immunodeficiency virus infection: hope and despair.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Humans; In Vitro Techniques; Zalcitabine; Zidovudine | 1994 |
Current use of anti-HIV drugs in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine | 1993 |
[Antiretroviral treatment. Present and future of the combinations].
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; HIV-1; Humans; Zalcitabine; Zidovudine | 1996 |
Antiretroviral therapy: a guide to the most important trials.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1997 |
Zidovudine, didanosine, and zalcitabine in the treatment of HIV infection: meta-analyses of the randomised evidence. HIV Trialists' Collaborative Group.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Didanosine; Disease Progression; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Randomized Controlled Trials as Topic; Survival Rate; Time Factors; Zalcitabine; Zidovudine | 1999 |
[New therapeutic trends in AIDS].
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Deoxyadenosines; Didanosine; Dideoxynucleosides; Humans; Poly I-C; Poly U; Randomized Controlled Trials as Topic; Ribavirin; RNA, Double-Stranded; Zalcitabine; Zidovudine | 1992 |
New developments in antiretroviral drug therapy for HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Combinations; Drug Therapy, Combination; Gene Products, tat; HIV Infections; HIV-1; Humans; Protease Inhibitors; tat Gene Products, Human Immunodeficiency Virus; Zalcitabine; Zidovudine | 1992 |
Anti-human immunodeficiency virus therapeutics: now and the future.
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Dideoxynucleosides; HIV; HIV-1; Humans; Trichosanthin; Zalcitabine; Zidovudine | 1992 |
Treatment of HIV infection: the antiretroviral nucleoside analogues. Nucleoside analogues: combination therapy.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Evaluation; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Zalcitabine; Zidovudine | 1992 |
Treatment of HIV infection: the antiretroviral nucleoside analogues. Nucleoside analogues: adverse effects.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Zalcitabine; Zidovudine | 1992 |
Treatment of HIV infection: the antiretroviral nucleoside analogues. Nucleoside analogues: monotherapy.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Resistance, Microbial; HIV Infections; HIV-1; Humans; Time Factors; Zalcitabine; Zidovudine | 1992 |
HIV disease: therapy, related systemic and oral conditions--an update.
Topics: Acquired Immunodeficiency Syndrome; Bacterial Infections; Didanosine; HIV Infections; Humans; Mouth Diseases; Mycoses; Sarcoma, Kaposi; Virus Diseases; Zalcitabine; Zidovudine | 1992 |
Therapy of AIDS and AIDS-associated neoplasms.
Topics: Acquired Immunodeficiency Syndrome; Humans; Lymphoma, AIDS-Related; Sarcoma, Kaposi; Zalcitabine; Zidovudine | 1992 |
[Treatments of human immunodeficiency virus infection. Current developments].
Topics: Acquired Immunodeficiency Syndrome; Didanosine; HIV; HIV Infections; Humans; Zalcitabine; Zidovudine | 1991 |
New developments in dideoxynucleoside antiretroviral therapy for HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Dideoxynucleosides; HIV Infections; Humans; Zalcitabine; Zidovudine | 1991 |
HIV/AIDS pathogenesis and treatment: new twists and turns.
Topics: Acquired Immunodeficiency Syndrome; CD4-Positive T-Lymphocytes; Didanosine; Humans; Lymphocyte Depletion; Trichosanthin; Zalcitabine; Zidovudine | 1991 |
Pharmacodynamics of 2',3'-dideoxycytidine: an inhibitor of human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; DNA Polymerase II; HIV; Humans; Male; Phosphorylation; RNA-Directed DNA Polymerase; Zalcitabine | 1990 |
Hematologic effects of AIDS therapies.
Topics: Acquired Immunodeficiency Syndrome; Bone Marrow; Dideoxynucleosides; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Macrophage Colony-Stimulating Factor; Sarcoma, Kaposi; Zalcitabine; Zidovudine | 1991 |
Targeted therapy of human immunodeficiency virus-related disease.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine | 1991 |
Anti-retroviral therapy of human immunodeficiency virus infection: current strategies and challenges for the future.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Resistance; HIV; HIV Infections; Humans; Lymphoma, Non-Hodgkin; Retroviridae; Reverse Transcriptase Inhibitors; T-Lymphocytes, Helper-Inducer; Virus Replication; Zalcitabine; Zidovudine | 1991 |
Zidovudine and other reverse transcriptase inhibitors in the management of human immunodeficiency virus-related disease.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Child; Didanosine; Female; Foscarnet; HIV Infections; Humans; Phosphonoacetic Acid; Pregnancy; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 1991 |
Treatment of AIDS with combinations of antiretroviral agents.
Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Interferon Type I; Recombinant Proteins; Zalcitabine; Zidovudine | 1991 |
Safety and tolerance of dideoxycytidine as a single agent. Results of early-phase studies in patients with acquired immunodeficiency syndrome (AIDS) or advanced AIDS-related complex. Study Group of the AIDS Clinical Trials Group of the National Institute
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Drug Evaluation; Drug Tolerance; Gene Products, gag; HIV Antigens; HIV Core Protein p24; HIV-1; Humans; Viral Core Proteins; Zalcitabine | 1990 |
Treatment of human immunodeficiency virus-infected infants and young children with dideoxynucleosides.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Child; Child, Preschool; Dideoxynucleosides; Drug Tolerance; HIV; HIV Infections; Humans; Infant; Zalcitabine; Zidovudine | 1990 |
Alternating and intermittent regimens of zidovudine (3'-azido-3'-deoxythymidine) and dideoxycytidine (2',3'-dideoxycytidine) in the treatment of patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Clinical Protocols; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Zalcitabine; Zidovudine | 1990 |
AIDS Clinical Trials Group: phase I/II study of combination 2',3'-dideoxycytidine and zidovudine in patients with acquired immunodeficiency syndrome (AIDS) and advanced AIDS-related complex.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Clinical Protocols; Drug Evaluation; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine | 1990 |
Targets for antiviral therapy of human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Dideoxynucleosides; Drug Therapy, Combination; Genes, Regulator; HIV; Humans; Reverse Transcriptase Inhibitors; Virus Replication; Zalcitabine; Zidovudine | 1989 |
[Therapy of AIDS].
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Dideoxynucleosides; Humans; Opportunistic Infections; Zalcitabine; Zidovudine | 1988 |
The treatment of HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Evaluation; Foscarnet; Humans; Opportunistic Infections; Phosphonoacetic Acid; Zalcitabine; Zidovudine | 1988 |
48 trial(s) available for zalcitabine and Acquired Immune Deficiency Syndrome
| Article | Year |
|---|---|
Prognostic value of baseline human immunodeficiency virus type 1 DNA measurement for disease progression in patients receiving nucleoside therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; DNA, Viral; HIV-1; Humans; Multivariate Analysis; Prognosis; RNA, Viral; Zalcitabine; Zidovudine | 2003 |
Development of HIV-1 resistance to (-)2'-deoxy-3'-thiacytidine in patients with AIDS or advanced AIDS-related complex.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; AIDS-Related Complex; Base Sequence; DNA Primers; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Female; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Lamivudine; Male; Molecular Sequence Data; Mutation; Phenotype; Proviruses; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Zalcitabine | 1995 |
A phase I/II study of 2'-deoxy-3'-thiacytidine (lamivudine) in patients with advanced human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; beta 2-Microglobulin; Female; HIV Core Protein p24; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Time Factors; Zalcitabine | 1995 |
Health status and function with zidovudine or zalcitabine as initial therapy for AIDS. A randomized controlled trial. Roche 3300/ACTG 114 Study Group.
Topics: Acquired Immunodeficiency Syndrome; Adult; Female; Health Status; Humans; Male; Regression Analysis; Severity of Illness Index; Survival Analysis; Treatment Outcome; Zalcitabine; Zidovudine | 1995 |
Treatment options in zidovudine intolerance or failure.
Topics: Acquired Immunodeficiency Syndrome; Adult; Didanosine; Female; Follow-Up Studies; Humans; Male; Survival Rate; Time Factors; Treatment Failure; Zalcitabine; Zidovudine | 1994 |
A comparative trial of didanosine or zalcitabine after treatment with zidovudine in patients with human immunodeficiency virus infection. The Terry Beirn Community Programs for Clinical Research on AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; CD4-Positive T-Lymphocytes; Didanosine; Female; Follow-Up Studies; HIV Infections; Humans; Leukocyte Count; Male; Risk; Zalcitabine; Zidovudine | 1994 |
Zidovudine and dideoxycytidine differ in their effects on human immunodeficiency virus-induced pathologic activation of the immune system. AIDS Clinical Trial Research Group 047.
Topics: Acquired Immunodeficiency Syndrome; beta 2-Microglobulin; Biopterins; HIV Core Protein p24; Humans; Immune System; Neopterin; Zalcitabine; Zidovudine | 1994 |
Combination and monotherapy with zidovudine and zalcitabine in patients with advanced HIV disease. The NIAID AIDS Clinical Trials Group.
Topics: Acquired Immunodeficiency Syndrome; Adult; CD4-Positive T-Lymphocytes; Combined Modality Therapy; Disease Progression; Double-Blind Method; Female; HIV Core Protein p24; Humans; Lymphocyte Count; Male; Zalcitabine; Zidovudine | 1995 |
Hair loss associated with lamivudine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Alopecia; Antiviral Agents; Female; Humans; Lamivudine; Male; Middle Aged; Zalcitabine | 1994 |
Alternating and intermittent regimens of zidovudine and dideoxycytidine in patients with AIDS or AIDS-related complex.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; CD4-Positive T-Lymphocytes; Drug Administration Schedule; Drug Therapy, Combination; Female; Hematologic Diseases; HIV Core Protein p24; Humans; Leukocyte Count; Male; Peripheral Nervous System Diseases; Weight Gain; Zalcitabine; Zidovudine | 1993 |
Cytomegalovirus retinitis under combination therapy with zidovudine and dideoxycytidine in advanced human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; CD4-CD8 Ratio; Cytomegalovirus Retinitis; Drug Therapy, Combination; HIV Infections; Humans; Incidence; Male; Prospective Studies; Zalcitabine; Zidovudine | 1993 |
Pharmacokinetics of 2-fluorodideoxycytidine (2FddC) in patients infected with human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adolescent; Adult; Antiviral Agents; Biological Availability; Drug Administration Schedule; HIV Infections; Humans; Injections, Intravenous; Male; Middle Aged; Zalcitabine | 1993 |
The effect of food on pharmacokinetics of zalcitabine in HIV-positive patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Antiviral Agents; Biological Availability; Female; Food; HIV Infections; Humans; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zalcitabine | 1995 |
Low dose methotrexate, bleomycin, doxorubicin, cyclophosphamide, vincristine, and dexamethasone with zalcitabine in patients with acquired immunodeficiency syndrome-related lymphoma. Effect on human immunodeficiency virus and serum interleukin-6 levels ov
Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bleomycin; Cyclophosphamide; Dexamethasone; Doxorubicin; HIV Core Protein p24; HIV-1; Humans; Interleukin-6; Leucovorin; Lymphoma, AIDS-Related; Male; Methotrexate; Middle Aged; Peripheral Nervous System Diseases; Remission Induction; Vincristine; Zalcitabine | 1996 |
Zidovudine alone or in combination with didanosine or zalcitabine in HIV-infected patients with the acquired immunodeficiency syndrome or fewer than 200 CD4 cells per cubic millimeter. Investigators for the Terry Beirn Community Programs for Clinical Rese
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Disease-Free Survival; Drug Therapy, Combination; Female; Humans; Male; Risk; Survival Analysis; Zalcitabine; Zidovudine | 1996 |
AIDS therapy with two, three or four agent combinations, applied in short sequences, differing from each other by drug rotation. I. First of two parts: a phase I trial equivalent, concerning five virostatics: AZT, ddI, ddC, acriflavine and an ellipticine
Topics: Acquired Immunodeficiency Syndrome; Acriflavine; Adult; Anti-Infective Agents; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Ellipticines; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Zalcitabine; Zidovudine | 1996 |
A pooled analysis of CD4 response to zidovudine and zalcitabine treatment in patients with AIDS and AIDS-related complex.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Humans; Regression Analysis; Time Factors; Zalcitabine; Zidovudine | 1997 |
Acetyl-carnitine deficiency in AIDS patients with neurotoxicity on treatment with antiretroviral nucleoside analogues.
Topics: Acetylcarnitine; Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Axons; Cross-Sectional Studies; Didanosine; Female; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine | 1997 |
[Effect of treatment with nucleoside analogues in subjects with primary genotypic resistance to zidovudine].
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance; Drug Therapy, Combination; Genotype; HIV-1; Humans; Zalcitabine; Zidovudine | 1996 |
Evaluation of pharmacokinetics, safety, tolerance, and activity of combination of zalcitabine and zidovudine in stable, zidovudine-treated pediatric patients with human immunodeficiency virus infection. AIDS Clinical Trials Group Protocol 190 Team.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cause of Death; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Incidence; Infant; Male; Neutropenia; Survival Rate; Time Factors; Zalcitabine; Zidovudine | 1997 |
Monitoring responses to antiretroviral treatment in human immunodeficiency virus type 1 (HIV-1)-infected patients by serial lymph node aspiration.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Biopsy, Needle; CD4 Lymphocyte Count; CD4-CD8 Ratio; Double-Blind Method; Drug Monitoring; Drug Therapy, Combination; HIV-1; Humans; Lymph Nodes; Polymerase Chain Reaction; Regression Analysis; RNA Splicing; RNA, Viral; Saquinavir; Single-Blind Method; Viremia; Zalcitabine; Zidovudine | 1997 |
Randomised trial of addition of lamivudine or lamivudine plus loviride to zidovudine-containing regimens for patients with HIV-1 infection: the CAESAR trial.
Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Health Services; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 1997 |
The effects of lamivudine treatment on HIV-1 disease progression are highly correlated with plasma HIV-1 RNA and CD4 cell count.
Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; RNA, Viral; Treatment Outcome; Viral Load; Zalcitabine; Zidovudine | 1998 |
A randomized, controlled, double-blind study comparing the survival benefit of four different reverse transcriptase inhibitor therapies (three-drug, two-drug, and alternating drug) for the treatment of advanced AIDS. AIDS Clinical Trial Group 193A Study T
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease-Free Survival; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV; Humans; Male; Nevirapine; Placebos; Reverse Transcriptase Inhibitors; RNA, Viral; Survival Rate; Time Factors; Zalcitabine; Zidovudine | 1998 |
Resistance mutations to zidovudine and saquinavir in patients receiving zidovudine plus saquinavir or zidovudine and zalcitabine plus saquinavir in AIDS clinical trials group 229.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Codon; Cohort Studies; Double-Blind Method; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Protease; HIV-1; Humans; Mutation; RNA, Viral; Saquinavir; Time Factors; Zalcitabine; Zidovudine | 1999 |
Characterizing patterns of drug-taking behavior with a multiple drug regimen in an AIDS clinical trial.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Anti-HIV Agents; Didanosine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Patient Compliance; Reverse Transcriptase Inhibitors; Time Factors; Zalcitabine; Zidovudine | 1998 |
The extent of non-adherence in a large AIDS clinical trial using plasma dideoxynucleoside concentrations as a marker.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Anti-HIV Agents; Didanosine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Patient Compliance; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 1998 |
FDA Committee recommends clearance for HIVID combination therapy.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; HIV Infections; Humans; Reverse Transcriptase Inhibitors; Time Factors; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1996 |
Merck protease inhibitor trial seeks persons with CD4 count under 50.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4 Lymphocyte Count; Drug Industry; Drug Therapy, Combination; HIV Protease Inhibitors; Hotlines; Humans; Indinavir; Lamivudine; Patient Selection; Pyridines; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine | 1995 |
New protease inhibitor studies.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Pyridines; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine | 1995 |
Observations of HIV-1 genotypic drug resistance in a trial of four reverse transcriptase inhibitors (Quattro Trial).
Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Viral Load; Zalcitabine; Zidovudine | 2002 |
[Efficacy and tolerance of dideoxynucleosides in HIV infection].
Topics: Acquired Immunodeficiency Syndrome; HIV Seropositivity; Humans; Zalcitabine; Zidovudine | 1992 |
Therapy of AIDS and AIDS-associated neoplasms.
Topics: Acquired Immunodeficiency Syndrome; Humans; Lymphoma, AIDS-Related; Sarcoma, Kaposi; Zalcitabine; Zidovudine | 1992 |
WSU part of national study to test AIDS therapies.
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; Michigan; Zalcitabine | 1991 |
Henry Ford begins clinical trial of two new AIDS therapies.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Humans; Zalcitabine | 1991 |
Treatment of AIDS with combinations of antiretroviral agents.
Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Interferon Type I; Recombinant Proteins; Zalcitabine; Zidovudine | 1991 |
A pilot study of the bioavailability and pharmacokinetics of 2',3'-dideoxycytidine in patients with AIDS or AIDS-related complex.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; AIDS-Related Complex; Biological Availability; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Pilot Projects; Zalcitabine | 1990 |
Alternating and intermittent regimens of zidovudine (3'-azido-3'-deoxythymidine) and dideoxycytidine (2',3'-dideoxycytidine) in the treatment of patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Clinical Protocols; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Zalcitabine; Zidovudine | 1990 |
Inhibition of HIV-1 in monocyte/macrophage cultures by 2',3'-dideoxycytidine-5'-triphosphate, free and in liposomes.
Topics: Acquired Immunodeficiency Syndrome; Antibodies; Antiviral Agents; Capsules; Cells, Cultured; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Deoxycytosine Nucleotides; Dideoxynucleotides; Drug Carriers; HIV-1; Humans; Immunoglobulin G; Kinetics; Liposomes; Macrophages; Monocytes; Virus Replication; Zalcitabine | 1990 |
Nutritional status of HIV-infected patients during the early disease stages.
Topics: Acquired Immunodeficiency Syndrome; Adult; Diet; Double-Blind Method; Energy Intake; Hematocrit; Hemoglobins; Humans; Male; Middle Aged; Nutritional Requirements; Nutritional Status; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine | 1990 |
Dideoxycytidine alone and in an alternating schedule with zidovudine in children with symptomatic human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adolescent; Age Factors; Antigens, CD; CD4 Antigens; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Male; Neuropsychological Tests; Time Factors; Zalcitabine; Zidovudine | 1990 |
Circulating p24 antigen levels and responses to dideoxycytidine in human immunodeficiency virus (HIV) infections. A phase I and II study.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; AIDS-Related Complex; Dideoxynucleosides; Drug Evaluation; Female; HIV Antigens; HIV Core Protein p24; Humans; Male; Random Allocation; Retroviridae Proteins; Zalcitabine | 1989 |
FDA expands testing of anti-AIDS drugs.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Dementia Complex; AIDS-Related Complex; Antiviral Agents; Clinical Trials as Topic; Didanosine; Humans; Infant; Infant, Newborn; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1989 |
Progress in antiviral drug and vaccine development assessed at international AIDS conference.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Drug Evaluation; Drug Therapy, Combination; Humans; Ribavirin; Thymidine; Viral Vaccines; Zalcitabine; Zidovudine | 1987 |
AIDS. Treatment strategies and the Minnesota AIDS Clinical Trials Unit.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Humans; Opportunistic Infections; Thymidine; Zalcitabine; Zidovudine | 1988 |
The treatment of HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Evaluation; Foscarnet; Humans; Opportunistic Infections; Phosphonoacetic Acid; Zalcitabine; Zidovudine | 1988 |
New treatment being tested against AIDS and ARC.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Clinical Trials as Topic; HIV; Humans; Virus Replication; Zalcitabine | 1987 |
[Azidothymidine and HIV infection].
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Drug Interactions; Humans; Thymidine; Zalcitabine; Zidovudine | 1987 |
155 other study(ies) available for zalcitabine and Acquired Immune Deficiency Syndrome
| Article | Year |
|---|---|
Potential anti-AIDS drugs. 2',3'-Dideoxycytidine analogues.
Topics: Acquired Immunodeficiency Syndrome; Cell Line; Chemical Phenomena; Chemistry; Deoxycytidine; HIV; Structure-Activity Relationship; T-Lymphocytes, Helper-Inducer; Zalcitabine | 1987 |
In vitro anti-human immunodeficiency virus (HIV) activity of the chromanone derivative, 12-oxocalanolide A, a novel NNRTI.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cell Line; Chromones; Coumarins; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Leukocytes; Macrophages; Monocytes; Pyranocoumarins; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Structure-Activity Relationship; Virus Replication | 1998 |
Simple adjustments for randomized trials with nonrandomly missing or censored outcomes arising from informative covariates.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Humans; Likelihood Functions; Longitudinal Studies; Models, Statistical; Nevirapine; Proportional Hazards Models; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome; Zalcitabine; Zidovudine | 2006 |
Mechanically-evoked C-fiber activity in painful alcohol and AIDS therapy neuropathy in the rat.
Topics: Acquired Immunodeficiency Syndrome; Alcoholic Neuropathy; Animals; Comorbidity; Disease Models, Animal; Ethanol; Mechanics; Mechanotransduction, Cellular; Nerve Fibers, Unmyelinated; Pain; Peripheral Nervous System Diseases; Rats; Zalcitabine | 2007 |
Confusion reigns over compassionate use of AIDS drug.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; France; Humans; Lamivudine; Zalcitabine | 1995 |
Infectious amplification of wild-type human immunodeficiency virus from patients' lymphocytes and modulation by reverse transcriptase inhibitors in vitro.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cells, Cultured; Dideoxynucleosides; Drug Interactions; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Lymphocyte Activation; Lymphocytes; Models, Biological; Reproducibility of Results; Reverse Transcriptase Inhibitors; Virus Replication; Zalcitabine; Zidovudine | 1993 |
[AIDS therapy with reverse transcriptase inhibitors].
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Drug Therapy, Combination; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 1993 |
Bisheteroarylpiperazine reverse transcriptase inhibitor in combination with 3'-azido-3'-deoxythymidine or 2',3'-dideoxycytidine synergistically inhibits human immunodeficiency virus type 1 replication in vitro.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Delavirdine; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Leukocytes, Mononuclear; Piperazines; Reverse Transcriptase Inhibitors; Virus Replication; Zalcitabine; Zidovudine | 1994 |
[Anti-HIV-therapy. Monotherapy with drugs delaying the course of the disease has limited effect].
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV Infections; Humans; Palliative Care; Zalcitabine; Zidovudine | 1994 |
Fighting all the time.
Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Virus Replication; Zalcitabine; Zidovudine | 1995 |
Risk factors for dideoxynucleoside-induced toxic neuropathy in patients with the human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Incidence; Male; Middle Aged; Peripheral Nervous System Diseases; Retrospective Studies; Risk Factors; Zalcitabine | 1995 |
Other AIDS drug regimens beat AZT alone, reduce clinical progression and mortality.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 1995 |
Drugs for AIDS and associated infections.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiprotozoal Agents; Antiviral Agents; Atovaquone; Candidiasis, Oral; Clindamycin; Clotrimazole; Cryptosporidiosis; Cytomegalovirus Infections; Dapsone; Didanosine; Drug Combinations; Drug Therapy, Combination; Fluconazole; Flucytosine; Folic Acid Antagonists; Foscarnet; Glucuronates; Herpes Simplex; Herpes Zoster; Humans; Isoniazid; Itraconazole; Ketoconazole; Lamivudine; Mycobacterium avium-intracellulare Infection; Naphthoquinones; Nystatin; Pentamidine; Pneumocystis Infections; Pneumonia, Pneumocystis; Prednisone; Primaquine; Reverse Transcriptase Inhibitors; Stavudine; Syphilis; Toxoplasmosis; Trimetrexate; Tuberculosis; Zalcitabine; Zidovudine | 1995 |
AZT combination trial shows positive results.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine | 1995 |
Confirmation for combination AIDS therapy.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Controlled Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Multicenter Studies as Topic; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 1995 |
Effect of zidovudine and didanosine treatment on heart function in children infected with human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Cardiomyopathies; CD4 Lymphocyte Count; Child, Preschool; Didanosine; Dose-Response Relationship, Drug; Echocardiography; Female; Heart; HIV; Humans; Infant; Infant, Newborn; Male; Medical Records; Retrospective Studies; Severity of Illness Index; Zalcitabine; Zidovudine | 1995 |
[AIDS: combination drug partner for AZT. HIV infection--new nucleoside analog].
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine | 1994 |
Didanosine-induced hypertriglyceridemia.
Topics: Acquired Immunodeficiency Syndrome; Adult; Didanosine; Humans; Hypertriglyceridemia; Male; Zalcitabine | 1995 |
Exacerbation of peripheral neuropathy by lamivudine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Humans; Lamivudine; Male; Peripheral Nervous System Diseases; Zalcitabine | 1995 |
AIDS mood upbeat--for a change.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; Gene Products, nef; Herpesviridae; HIV; Humans; Lamivudine; nef Gene Products, Human Immunodeficiency Virus; Sarcoma, Kaposi; Simian Immunodeficiency Virus; Virus Replication; Zalcitabine; Zidovudine | 1995 |
Lower socioeconomic status and shorter survival following HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; British Columbia; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Health Services; HIV Infections; HIV Seropositivity; Homosexuality, Male; Humans; Income; Male; Pneumonia, Pneumocystis; Regression Analysis; Socioeconomic Factors; Survival Rate; Zalcitabine; Zidovudine | 1994 |
US AIDS activists urge caution on new anti-HIV drugs.
Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Drug Approval; Humans; Politics; United States; Zalcitabine | 1994 |
[The anti-viral agents used in the treatment of AIDS].
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; Zalcitabine; Zidovudine | 1994 |
Schwann cell mitochondrial alterations in peripheral nerves of rabbits treated with 2',3'-dideoxycytidine.
Topics: Acquired Immunodeficiency Syndrome; Animals; Ganglia, Spinal; Humans; Microscopy, Electron; Mitochondria; Neurotoxins; Rabbits; Reference Values; Schwann Cells; Sciatic Nerve; Tibial Nerve; Zalcitabine | 1994 |
The drugs 2',3'-dideoxyinosine (ddI) and 2',3'-dideoxycytidine (ddC) are safe alternatives in people with AIDS with zidovudine-induced myopathy.
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; Male; Muscular Diseases; Zalcitabine; Zidovudine | 1994 |
Dideoxynucleoside resistance emerges with prolonged zidovudine monotherapy. The RV43 Study Group.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Didanosine; Drug Resistance, Microbial; HIV Seropositivity; HIV-1; Humans; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Time Factors; Zalcitabine; Zidovudine | 1994 |
Human immunodeficiency virus type 1 pol gene mutations in an AIDS patient treated with multiple antiretroviral drugs.
Topics: Acquired Immunodeficiency Syndrome; Amino Acid Sequence; Base Sequence; Consensus Sequence; Didanosine; Genes, pol; Genotype; HIV-1; Humans; Leukocytes, Mononuclear; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Point Mutation; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Time Factors; Viral Plaque Assay; Zalcitabine; Zidovudine | 1993 |
Anti-human immunodeficiency virus type 1 therapy and peripheral neuropathy: prevention of 2',3'-dideoxycytidine toxicity in PC12 cells, a neuronal model, by uridine and pyruvate.
Topics: Acquired Immunodeficiency Syndrome; Animals; Cell Survival; DNA Replication; DNA, Mitochondrial; HIV-1; Models, Biological; Neurons; PC12 Cells; Peripheral Nervous System Diseases; Pyruvates; Pyruvic Acid; Uridine; Zalcitabine | 1993 |
Changes in drug sensitivity of human immunodeficiency virus type 1 during therapy with azidothymidine, dideoxycytidine, and dideoxyinosine: an in vitro comparative study.
Topics: Acquired Immunodeficiency Syndrome; Amino Acid Sequence; Base Sequence; Didanosine; Dose-Response Relationship, Drug; Genetic Variation; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Homology, Amino Acid; Zalcitabine; Zidovudine | 1993 |
Generation of drug-resistant variants of human immunodeficiency virus type 1 by in vitro passage in increasing concentrations of 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Resistance; HIV Infections; HIV-1; Humans; Lamivudine; Zalcitabine | 1993 |
Differential phosphorylation of azidothymidine, dideoxycytidine, and dideoxyinosine in resting and activated peripheral blood mononuclear cells.
Topics: 5'-Nucleotidase; Acquired Immunodeficiency Syndrome; Adenosine Kinase; AIDS-Related Complex; Chromatography, High Pressure Liquid; Deoxycytidine Kinase; Deoxyribonucleotides; Didanosine; HIV-1; Humans; Kinetics; Microbial Sensitivity Tests; Monocytes; Phosphorylation; Thymidine Kinase; Uridine Kinase; Zalcitabine; Zidovudine | 1993 |
Somber news from the AIDS front.
Topics: Acquired Immunodeficiency Syndrome; AIDS Vaccines; Drug Therapy, Combination; Female; Humans; Immunity, Cellular; Male; Sexually Transmitted Diseases; Zalcitabine; Zidovudine | 1993 |
High-level resistance to zidovudine but not to zalcitabine or didanosine in human immunodeficiency virus from children receiving antiretroviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Child; Child, Preschool; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV-1; Humans; Infant; Microbial Sensitivity Tests; Mutation; Polymerase Chain Reaction; Time Factors; Zalcitabine; Zidovudine | 1993 |
Effect of 3'-azido-3'-deoxythymidine on human immunodeficiency virus type 1 replication in human fetal brain macrophages.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Brain; Cells, Cultured; DNA, Viral; Fetus; HIV Core Protein p24; HIV-1; Humans; Lamivudine; Macrophages; RNA, Messenger; Stereoisomerism; Time Factors; Virus Replication; Zalcitabine; Zidovudine | 1993 |
Pancreatitis possibly related to 2'-3'-dideoxycytidine.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; Female; Humans; Pancreatitis; Zalcitabine | 1993 |
A pilot study of sequential therapy with zidovudine plus acyclovir, dideoxyinosine, and dideoxycytidine in patients with severe human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; AIDS-Related Complex; Antigens, CD; Biomarkers; Body Weight; CD4 Antigens; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; HIV Core Protein p24; Humans; Male; Middle Aged; Pilot Projects; T-Lymphocyte Subsets; Time Factors; Zalcitabine; Zidovudine | 1993 |
Preliminary study analysis suggests similar efficacy for didanosine and zalcitabine.
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; Treatment Outcome; Zalcitabine; Zidovudine | 1993 |
[Is early combined AIDS treatment an advantage? Nucleoside analogs--study will bring enlightenment].
Topics: Acquired Immunodeficiency Syndrome; Drug Therapy, Combination; Humans; Leukocyte Count; T-Lymphocytes, Helper-Inducer; Zalcitabine; Zidovudine | 1993 |
Activists now urge caution on approval of new AIDS drug.
Topics: Acquired Immunodeficiency Syndrome; Drug Approval; Federal Government; Government Regulation; Humans; Politics; Therapeutic Human Experimentation; United States; United States Food and Drug Administration; Zalcitabine | 1993 |
A new HIV/AIDS drug.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Zalcitabine; Zidovudine | 1996 |
Managing HIV disease after Delta.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Combinations; HIV Infections; Humans; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine | 1996 |
Lamivudine as adjunct therapy in HIV.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zalcitabine; Zidovudine | 1996 |
HIV's Achilles' heel. Drugs and education are starting to slow the AIDS virus.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; Health Education; Humans; Indinavir; Lamivudine; Pyridines; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 1996 |
Anti-CD4 therapy for AIDS suggested by mathematical models.
Topics: Acquired Immunodeficiency Syndrome; Antigens, CD; Antiviral Agents; CD4 Antigens; CD4 Lymphocyte Count; HIV-1; Host-Parasite Interactions; Humans; Lamivudine; Models, Theoretical; Zalcitabine | 1996 |
Therapy for human immunodeficiency virus infection -- what have we learned?
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Zalcitabine; Zidovudine | 1996 |
[HIV: to administer protease inhibitors early].
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Time Factors; Zalcitabine; Zidovudine | 1996 |
The Delta trial.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Zalcitabine; Zidovudine | 1997 |
Treatment of late-state HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Combinations; HIV Infections; Humans; Randomized Controlled Trials as Topic; Reproducibility of Results; Reverse Transcriptase Inhibitors; Treatment Outcome; Zalcitabine; Zidovudine | 1997 |
The impact of ethanol and Marinol/marijuana usage on HIV+/AIDS patients undergoing azidothymidine, azidothymidine/dideoxycytidine, or dideoxyinosine therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Alcohol Drinking; Amylases; Anti-HIV Agents; Appetite Stimulants; CD4 Lymphocyte Count; Didanosine; Dronabinol; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Seropositivity; Humans; Liver Function Tests; Male; Marijuana Smoking; Middle Aged; Pancreatitis, Alcoholic; Zalcitabine; Zidovudine | 1997 |
Treatment options for human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Child; Didanosine; Drug Approval; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Lamivudine; Male; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1996 |
[Therapeutic strategies against HIV: status in 1994 and future prospectives].
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Forecasting; HIV Infections; Humans; Male; Zalcitabine; Zidovudine | 1994 |
Lack of mitochondrial toxicity in CEM cells treated with carbovir.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cell Line; Dideoxynucleosides; DNA, Mitochondrial; Drug Evaluation, Preclinical; Humans; Lactic Acid; Mitochondria; Prodrugs; Zalcitabine | 1997 |
Correlation of ribonucleic acid polymerase chain reaction, acid dissociated p24 antigen, and neopterin with progression of disease. A retrospective, longitudinal study of vertically acquired human immunodeficiency virus type 1 infection in children.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Biopterins; CD4 Lymphocyte Count; Child; Child, Preschool; Female; HIV Core Protein p24; HIV-1; Humans; Infant; Longitudinal Studies; Male; Neopterin; Polymerase Chain Reaction; Retrospective Studies; RNA, Viral; Viral Load; Zalcitabine; Zidovudine | 1997 |
Cure or control of HIV/AIDS?
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Models, Biological; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1997 |
Antiviral potency of drug-gene therapy combinations against human immunodeficiency virus type 1.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cell Line; Combined Modality Therapy; DNA, Recombinant; Dose-Response Relationship, Drug; Gene Products, gag; Gene Products, rev; Genetic Therapy; Genetic Vectors; Genome, Viral; HIV Core Protein p24; HIV-1; Humans; Indinavir; rev Gene Products, Human Immunodeficiency Virus; RNA, Antisense; T-Lymphocytes; Zalcitabine; Zidovudine | 1997 |
[Esophageal ulcer in a patient with AIDS].
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Diagnosis, Differential; Esophageal Diseases; Esophagitis; Humans; Male; Ulcer; Zalcitabine | 1997 |
[Initial administration of a protease inhibitor delays the progression of AIDS by half time].
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Disease Progression; HIV Infections; HIV Protease Inhibitors; Humans; Time Factors; Zalcitabine; Zidovudine | 1997 |
Zalcitabine population pharmacokinetics: application of radioimmunoassay.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Female; Humans; Male; Radioimmunoassay; Zalcitabine | 1998 |
Risk of HIV dementia and opportunistic brain disease in AIDS and zidovudine therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Dementia Complex; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Brain Diseases; Didanosine; Female; Follow-Up Studies; Humans; Longitudinal Studies; Male; Retrospective Studies; Risk; Stavudine; Treatment Outcome; Zalcitabine; Zidovudine | 1998 |
Cost effectiveness of antiviral treatment with zalcitabine plus zidovudine for AIDS patients with CD4+ counts less than 300/microliters in 5 European countries.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Cost-Benefit Analysis; Cross-Cultural Comparison; Drug Costs; Europe; Follow-Up Studies; Humans; Zalcitabine; Zidovudine | 1994 |
Data and safety monitoring in the Delta trial.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Double-Blind Method; Drug Therapy, Combination; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Survival Analysis; Zalcitabine; Zidovudine | 1999 |
Relevance of AIDS treatment with two nucleoside analogues alone.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Humans; Survival Rate; Zalcitabine; Zidovudine | 1999 |
Presence of genotypic resistance in nucleoside analogue-treated HIV-1-infected patients with undetectable viral load.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance; Genes, pol; Genotype; HIV-1; Humans; Lamivudine; Point Mutation; RNA, Viral; Zalcitabine; Zidovudine | 1999 |
Different outcome in the first two patients with an HIV-1 multinucleoside drug-resistant T69SSS insertion in Spain.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Didanosine; Drug Resistance, Multiple; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mutation; Spain; Zalcitabine; Zidovudine | 1999 |
Lipemia retinalis in acquired immunodeficiency syndrome treated with protease inhibitors.
Topics: Acquired Immunodeficiency Syndrome; Adult; Cholesterol; Delavirdine; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Hyperlipidemias; Male; Retinal Diseases; Retinal Vessels; Ritonavir; Saquinavir; Triglycerides; Viral Load; Zalcitabine | 2000 |
Using conditional logistic regression to fit proportional odds models to interval censored data.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Biometry; CD4 Lymphocyte Count; Drug Therapy, Combination; Humans; Likelihood Functions; Models, Statistical; Regression Analysis; Statistics, Nonparametric; Survival Analysis; Zalcitabine; Zidovudine | 2000 |
Reductions in viral load and increases in T lymphocyte numbers in treatment-naive patients with advanced HIV-1 infection treated with ritonavir, zidovudine and zalcitabine triple therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Female; HIV-1; Humans; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; Ritonavir; RNA, Viral; Zalcitabine; Zidovudine | 1997 |
Plasma HIV-1 RNA as a predictor of the efficacy of adding zalcitabine to a previous regimen with zidovudine.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV-1; Humans; Male; Prospective Studies; RNA, Viral; Zalcitabine; Zidovudine | 1996 |
Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA; DNA Polymerase gamma; DNA Replication; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Exodeoxyribonucleases; Humans; Kinetics; Lamivudine; Mitochondria; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Zalcitabine | 2001 |
AIDS task force grapples with faster access to protease drugs.
Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; Drug Approval; Drug Design; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Pyridines; Treatment Outcome; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1995 |
Drug companies seek trial participants.
Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Drug Industry; Drug Therapy, Combination; HIV Protease Inhibitors; Hotlines; Humans; Patient Selection; United States; Zalcitabine; Zidovudine | 1995 |
Combination treatment and single drugs: interview with Margaret Poscher, M.D. Interview by John S. James.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Approval; Drug Combinations; Drug Therapy, Combination; Health Services Accessibility; Humans; Insurance, Health; Lamivudine; Managed Care Programs; United States; Zalcitabine; Zidovudine | 1995 |
3TC: now available again up to CD4 of 300.
Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; Drug Industry; Drug Therapy, Combination; Humans; Lamivudine; Patient Selection; United States; Zalcitabine; Zidovudine | 1995 |
AZT delta study: major European/Australian study finds combinations better than AZT alone.
Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine | 1995 |
Protease inhibitors and prevention of cross resistance.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Carbamates; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Isoquinolines; Lamivudine; Nelfinavir; Pyridines; Quinolines; Saquinavir; Sulfonamides; Zalcitabine; Zidovudine | 1995 |
Glaxo broadens access to 3TC.
Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Zalcitabine | 1995 |
Roaches of inner space.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Lamivudine; Mutation; T-Lymphocytes, Cytotoxic; Virulence; Virus Replication; Zalcitabine; Zidovudine | 1995 |
ACTG 175 and Delta.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Evaluation Studies as Topic; Humans; Treatment Outcome; Zalcitabine; Zidovudine | 1995 |
Making sense of 175 and Delta.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Approval; Drug Resistance, Microbial; Drug Therapy, Combination; Evaluation Studies as Topic; Humans; Zalcitabine; Zidovudine | 1995 |
New trials reach same conclusion: two drugs are better than AZT alone.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Data Interpretation, Statistical; Didanosine; Drug Therapy, Combination; Humans; Treatment Outcome; Zalcitabine; Zidovudine | 1995 |
Study results at a glance.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine | 1995 |
FDA triple header. Food and Drug Administration.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Mutation; Quinolines; Salvage Therapy; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1995 |
FDA antiviral advisory hearings on lamivudine (Epivir, 3TC), saquinavir (Invirase), stavudine (Zerit, d4T), November 6-8. Food and Drug Administration.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Drug Resistance, Microbial; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Quinolines; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine | 1995 |
To treat or not to treat--approaches to antiretroviral therapy. Interview by Anthony J. Japour.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Didanosine; Drug Therapy, Combination; HIV; Humans; Lamivudine; Practice Patterns, Physicians'; RNA, Viral; Zalcitabine; Zidovudine | 1996 |
Major protease inhibitor triple combination trial begins soon: CD4 under 200, AZT experienced, 3TC naive.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Zalcitabine; Zidovudine | 1995 |
Potent new AIDS drugs underscore promise of combination therapy.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Drug Approval; Drug Resistance; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Seropositivity; Humans; Isoquinolines; Lamivudine; Quinolines; Saquinavir; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1996 |
Protease inhibitors shine in triple combinations.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Pyridines; Ritonavir; Thiazoles; Valine; Zalcitabine; Zidovudine | 1996 |
AZT, ddI, and ddC combinations at FDA advisory hearing. Food and Drug Administration.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine | 1996 |
Europe out of step with the US.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Costs; Europe; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Quinolines; Ritonavir; Saquinavir; Thiazoles; United States; Valine; Zalcitabine; Zidovudine | 1996 |
ACTG 175: new insights into treating patients with intermediate-stage HIV disease.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine | 1995 |
Saquinavir plus ddC reduces deaths by more than two-thirds.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Isoquinolines; Quinolines; Saquinavir; Survival Rate; Zalcitabine | 1996 |
Top AIDS researchers' strategy for antiretroviral treatment.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Patient Compliance; Practice Guidelines as Topic; RNA, Viral; Stavudine; Zalcitabine; Zidovudine | 1996 |
Outdated yet out-of-reach: AIDS society treatment guidelines at the International Conference.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Decision Making; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Practice Guidelines as Topic; Zalcitabine; Zidovudine | 1996 |
Mitochondrial alterations with mitochondrial DNA depletion in the nerves of AIDS patients with peripheral neuropathy induced by 2'3'-dideoxycytidine (ddC).
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; DNA, Mitochondrial; Humans; Microscopy, Electron; Middle Aged; Mitochondria; Peripheral Nervous System Diseases; Schwann Cells; Sural Nerve; Zalcitabine | 2001 |
Viral and immunologic follow up of 4 to 9 years of AIDS treatments by quadruple combinations of virostatics including integrase inhibitors applied in short sequences differing by drug rotation.
Topics: Acquired Immunodeficiency Syndrome; Acriflavine; Adult; Anti-HIV Agents; Antiviral Agents; CD4-CD8 Ratio; Didanosine; Drug Therapy, Combination; Ellipticines; Female; Follow-Up Studies; HIV-1; Humans; Integrase Inhibitors; Male; Middle Aged; Protease Inhibitors; Stavudine; Vitamin B 12; Zalcitabine; Zidovudine | 2002 |
Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine.
Topics: Acquired Immunodeficiency Syndrome; Base Sequence; Cell Line; Cloning, Molecular; Didanosine; Drug Resistance, Microbial; Genetic Variation; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Restriction Mapping; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine | 1992 |
Decreases in unintegrated HIV DNA are associated with antiretroviral therapy in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; DNA, Viral; Drug Resistance, Microbial; HIV-1; Humans; Leukocytes, Mononuclear; Molecular Weight; Polymerase Chain Reaction; Virus Integration; Zalcitabine; Zidovudine | 1992 |
FDA warns quality of underground zalcitabine is poor; Roche expands premarketing access programs.
Topics: Acquired Immunodeficiency Syndrome; Drug Industry; Humans; Quality Control; United States; United States Food and Drug Administration; Zalcitabine | 1992 |
Human immunodeficiency virus type 1 pol gene mutations which cause decreased susceptibility to 2',3'-dideoxycytidine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amino Acid Sequence; Base Sequence; Drug Resistance, Microbial; Genes, pol; HIV-1; Humans; Hybridization, Genetic; Male; Molecular Sequence Data; Mutation; Zalcitabine | 1992 |
FDA urges buyers' clubs to stop sales of underground ddC; Roche expands premarketing access programs.
Topics: Acquired Immunodeficiency Syndrome; Drug Industry; Humans; Quality Control; United States; United States Food and Drug Administration; Zalcitabine | 1992 |
Cellular metabolism of (-) enantiomeric 2'-deoxy-3'-thiacytidine.
Topics: Acquired Immunodeficiency Syndrome; Blood Platelets; Cells, Cultured; Humans; Lamivudine; Lymphocytes; Pentosyltransferases; Phosphorylation; Pyrimidine Phosphorylases; Stereoisomerism; Thymidine Phosphorylase; Zalcitabine; Zidovudine | 1992 |
Isolation of experimental anti-AIDS glycerophospholipids by micro-preparative reversed-phase high-performance liquid chromatography.
Topics: Acquired Immunodeficiency Syndrome; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dideoxynucleotides; Phosphatidic Acids; Spectrophotometry, Ultraviolet; Zalcitabine; Zidovudine | 1992 |
AIDS drug made available.
Topics: Acquired Immunodeficiency Syndrome; Drug Industry; Drug Therapy, Combination; Humans; United States; Zalcitabine; Zidovudine | 1992 |
Treatment of HIV infection: the antiretroviral nucleoside analogues. Introduction.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Evaluation; HIV Infections; HIV-1; Humans; Nucleosides; Zalcitabine; Zidovudine | 1992 |
AIDS file. ddC gets FDA nod.
Topics: Acquired Immunodeficiency Syndrome; Humans; United States; United States Food and Drug Administration; Zalcitabine | 1992 |
Thermospray liquid chromatographic-mass spectrometric analysis of anti-AIDS nucleosides: quantification of 2',3'-dideoxycytidine in plasma samples.
Topics: Acquired Immunodeficiency Syndrome; Chromatography, Liquid; Humans; Mass Spectrometry; Reproducibility of Results; Zalcitabine | 1992 |
FDA approves new AIDS drug.
Topics: Acquired Immunodeficiency Syndrome; Drug Therapy, Combination; Humans; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1992 |
FDA approves AIDS drug.
Topics: Acquired Immunodeficiency Syndrome; Drug Approval; Drugs, Investigational; Humans; United States; United States Food and Drug Administration; Zalcitabine | 1992 |
[New AIDS drug: dideoxycytidine (DDC)].
Topics: Acquired Immunodeficiency Syndrome; Austria; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine | 1992 |
AZT and ddC work better together than alone.
Topics: Acquired Immunodeficiency Syndrome; CD4-Positive T-Lymphocytes; Drug Synergism; Humans; T-Lymphocytes; Zalcitabine; Zidovudine | 1992 |
[New, in Austria registered specialty drugs. Hivid (2',3'-dideoxycytidine; ddC)].
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Animals; Antiviral Agents; Austria; CD4-Positive T-Lymphocytes; Humans; Leukocyte Count; Zalcitabine; Zidovudine | 1992 |
[Another AIDS drug. Azidothymidine--dideoxycytidine].
Topics: Acquired Immunodeficiency Syndrome; CD4-Positive T-Lymphocytes; HIV; Humans; Leukocyte Count; Virus Replication; Zalcitabine; Zidovudine | 1992 |
Biological comparison of wild-type and zidovudine-resistant isolates of human immunodeficiency virus type 1 from the same subjects: susceptibility and resistance to other drugs.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytosine; Drug Resistance, Microbial; HIV-1; Humans; Lamivudine; Nucleosides; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine | 1991 |
Therapeutic options expand, take new directions.
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; United States; Zalcitabine; Zidovudine | 1991 |
AIDS. Conditional approval touted.
Topics: Acquired Immunodeficiency Syndrome; CD4 Antigens; Drug Therapy, Combination; Humans; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1991 |
Better AIDS treatments.
Topics: Acquired Immunodeficiency Syndrome; Drug Therapy, Combination; Humans; Opportunistic Infections; Pneumonia; Trimethoprim, Sulfamethoxazole Drug Combination; Zalcitabine; Zidovudine | 1991 |
AIDS drug update: DDI and DDC.
Topics: Acquired Immunodeficiency Syndrome; Adult; Didanosine; Humans; Male; Patient Education as Topic; Zalcitabine | 1991 |
[Dideoxycytidine and dideoxyinosine: new therapy for acquired immunodeficiency syndrome?].
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; Zalcitabine | 1991 |
Strength in numbers. Researchers begin combining compounds to fight AIDS.
Topics: Acquired Immunodeficiency Syndrome; CD4 Antigens; Didanosine; Drug Therapy, Combination; Humans; Interferons; Zalcitabine; Zidovudine | 1990 |
[Current practice and future prospects of AIDS-therapy].
Topics: Acquired Immunodeficiency Syndrome; Benzodiazepines; Drug Therapy, Combination; Humans; Imidazoles; Interferons; Thiones; Tumor Necrosis Factor-alpha; Zalcitabine; Zidovudine | 1990 |
[Inhibitors of HIV-1 reverse transcriptase and protease as chemotherapeutics for AIDS].
Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Didanosine; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Reverse Transcriptase Inhibitors; Thymine; Zalcitabine; Zidovudine | 1991 |
[Combination therapies with anti-retroviral agents in HIV and AIDS infections].
Topics: Acquired Immunodeficiency Syndrome; Anti-Bacterial Agents; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Interferons; Zalcitabine; Zidovudine | 1991 |
US drug regulation. AIDS politics change rules.
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Humans; Legislation, Drug; United States; United States Food and Drug Administration; Zalcitabine | 1991 |
[AIDS: initial results of combination therapy. AIDS and ARC--alternating or intermittent medication].
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; CD4 Antigens; Combined Modality Therapy; HIV; Humans; Immunotherapy, Adoptive; Interferon Type I; Recombinant Proteins; Zalcitabine; Zidovudine | 1991 |
Expanded access for AIDS drug.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Humans; Zalcitabine | 1991 |
High-performance liquid chromatographic method for the analysis of 2',3'-dideoxycytidine in human plasma.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Chromatography, High Pressure Liquid; Humans; Male; Regression Analysis; Zalcitabine | 1990 |
Surrogate markers of disease studied as means of determining AIDS drugs' effectiveness.
Topics: Acquired Immunodeficiency Syndrome; CD4-Positive T-Lymphocytes; Didanosine; Humans; Leukocyte Count; Zalcitabine | 1990 |
New AIDS drug.
Topics: Acquired Immunodeficiency Syndrome; Humans; Zalcitabine | 1990 |
Wider access provided to AIDS drugs with actions against HIV, CMV infections.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; HIV Infections; Humans; Phosphonoacetic Acid; Zalcitabine | 1990 |
Clinical trials of combination therapies for HIV infection. Discussion.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; Humans; Zalcitabine; Zidovudine | 1990 |
Clinical trials of combination therapies for HIV infection. Rationale for development of multidrug therapy.
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine | 1990 |
Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cell Line, Transformed; Colorimetry; Cytopathogenic Effect, Viral; Dextran Sulfate; Dextrans; Dideoxynucleosides; Drug Evaluation, Preclinical; Heparin; HIV; Humans; Tetrazolium Salts; Thiazoles; Zalcitabine; Zidovudine | 1988 |
HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Dideoxynucleosides; Drug Resistance; Foscarnet; HeLa Cells; HIV; HIV Core Protein p24; Humans; Microbial Sensitivity Tests; Phosphonoacetic Acid; Retroviridae Proteins; Reverse Transcriptase Inhibitors; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine | 1989 |
Inhibitory effect of azidothymidine, 2'-3'-dideoxyadenosine, and 2'-3'-dideoxycytidine on in vitro growth of hematopoietic progenitor cells from normal persons and from patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Bone Marrow; Colony-Forming Units Assay; Deoxyribonucleosides; Dideoxyadenosine; Dideoxynucleosides; Dose-Response Relationship, Drug; Growth Inhibitors; Hematopoiesis; Hematopoietic Stem Cells; Humans; Zalcitabine; Zidovudine | 1989 |
Feline leukemia virus-induced immunodeficiency syndrome in cats as a model for evaluation of antiretroviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Animals; Cats; Cell Line; Cytopathogenic Effect, Viral; Delayed-Action Preparations; Dideoxynucleosides; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Implants; Drug Therapy, Combination; Immunologic Deficiency Syndromes; Injections, Intravenous; Injections, Subcutaneous; Leukemia Virus, Feline; Leukemia, Experimental; Retroviridae Infections; Specific Pathogen-Free Organisms; Tetrahydrouridine; Viremia; Zalcitabine | 1989 |
Testing of nucleoside analogues in cats infected with feline leukemia virus: a model.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antibodies, Viral; Antiviral Agents; Cats; Cell Line; Didanosine; Dideoxyadenosine; Dideoxynucleosides; Disease Models, Animal; Drug Evaluation, Preclinical; Immunologic Deficiency Syndromes; Leukemia Virus, Feline; Leukemia, Experimental; Nucleosides; Specific Pathogen-Free Organisms; Virus Replication; Zalcitabine; Zidovudine | 1989 |
Treatment of FeLV-induced immunodeficiency syndrome (FeLV-FAIDS) with controlled release capsular implantation of 2',3'-dideoxycytidine.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antibodies, Monoclonal; Capsules; Cats; Dideoxynucleosides; Disease Models, Animal; Drug Implants; Drug Therapy, Combination; Gene Products, gag; Immunologic Deficiency Syndromes; Infusions, Intravenous; Injections, Subcutaneous; Interferon Type I; Leukemia Virus, Feline; Retroviridae Proteins; Tetrahydrouridine; Tumor Necrosis Factor-alpha; Virus Replication; Zalcitabine | 1989 |
Enzymatic and chemical stability of 2',3'-dideoxy-2',3'-didehydropyrimidine nucleosides: potential anti-acquired immunodeficiency syndrome agents.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Cytarabine; Dideoxynucleosides; Drug Stability; Humans; Mice; Stavudine; Zalcitabine | 1989 |
[AIDS: small, life-prolonging steps. Antiviral therapy is more efficient--a decrease in side effects].
Topics: Acquired Immunodeficiency Syndrome; HIV; Humans; Zalcitabine; Zidovudine | 1989 |
A comparison of three nucleoside analogs with anti-retroviral activity on immune and hematopoietic functions in mice: in vitro toxicity to precursor cells and microstromal environment.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antigen-Antibody Reactions; Antiviral Agents; Bone Marrow; Dideoxyadenosine; Female; Hematopoiesis; HIV; Immunity, Cellular; Macrophages; Mice; Mice, Inbred C57BL; Spleen; Stem Cells; T-Lymphocytes; Virus Replication; Zalcitabine; Zidovudine | 1989 |
2',3'-dideoxycytidine permeation of the human erythrocyte membrane.
Topics: Acquired Immunodeficiency Syndrome; Biological Transport; Diffusion; Dipyridamole; Erythrocyte Membrane; Hot Temperature; Humans; In Vitro Techniques; Thioinosine; Zalcitabine | 1989 |
Dermatologic complications associated with administration of 2',3'-dideoxycytidine in patients with human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Administration Schedule; Drug Eruptions; Drug Evaluation; HIV Antigens; Humans; Male; Middle Aged; Mouth Diseases; T-Lymphocytes, Helper-Inducer; Ulcer; Zalcitabine | 1989 |
Reversible axonal neuropathy from the treatment of AIDS and related disorders with 2',3'-dideoxycytidine (ddC).
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Axons; Dose-Response Relationship, Drug; Electromyography; Humans; Pain; Peripheral Nervous System Diseases; Zalcitabine | 1989 |
AZT/ddC combination may benefit AIDS sufferers.
Topics: Acquired Immunodeficiency Syndrome; Drug Combinations; Humans; Zalcitabine; Zidovudine | 1989 |
Several new AIDS drugs being tested.
Topics: 1-Deoxynojirimycin; Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; CD4 Antigens; Drug Therapy, Combination; Glucosamine; Humans; Interferon Type I; Sarcoma, Kaposi; Zalcitabine; Zidovudine | 1989 |
2',3'-Dideoxynucleoside phosphorylation by deoxycytidine kinase from normal human thymus extracts: activation of potential drugs for AIDS therapy.
Topics: Acquired Immunodeficiency Syndrome; Coformycin; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Dideoxyadenosine; Humans; Kinetics; Pentostatin; Phosphorylation; Phosphotransferases; Structure-Activity Relationship; Thymus Extracts; Thymus Gland; Zalcitabine | 1987 |
Therapy for neurological involvement in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Blood-Brain Barrier; Central Nervous System Diseases; Deoxycytidine; Humans; Immunotherapy; Molecular Biology; Retroviridae; Thymidine; Zalcitabine; Zidovudine | 1988 |
Unusual structural features of 2',3'-dideoxycytidine, an inhibitor of the HIV (AIDS) virus.
Topics: Acquired Immunodeficiency Syndrome; Chemical Phenomena; Chemistry; Crystallography; Deoxycytidine; HIV; Models, Molecular; Molecular Conformation; Zalcitabine | 1988 |
Genetic analysis of 2',3'-dideoxycytidine incorporation into cultured human T lymphoblasts.
Topics: Acquired Immunodeficiency Syndrome; Biological Transport; Cell Division; Cell Survival; Deoxycytidine; Deoxycytidine Kinase; Dipyridamole; Humans; Kinetics; Leukemia, Lymphoid; Mutation; Nucleosides; Phosphorylation; Phosphotransferases; T-Lymphocytes; Thioinosine; Tumor Cells, Cultured; Zalcitabine | 1988 |
Potent and selective activity of a new carbocyclic nucleoside analog (carbovir: NSC 614846) against human immunodeficiency virus in vitro.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Molecular Structure; Structure-Activity Relationship; Virus Replication; Zalcitabine; Zidovudine | 1988 |
Inhibition of bone marrow myelopoiesis and erythropoiesis in vitro by anti-retroviral nucleoside derivatives.
Topics: Acquired Immunodeficiency Syndrome; Bone Marrow; Cells, Cultured; Colony-Forming Units Assay; Depression, Chemical; Dideoxynucleosides; Erythropoiesis; Humans; Zalcitabine; Zidovudine | 1988 |
Quantification of dideoxycytidine in human plasma by gas chromatography/mass spectrometry.
Topics: Acquired Immunodeficiency Syndrome; Dideoxynucleosides; Gas Chromatography-Mass Spectrometry; Humans; Zalcitabine | 1988 |
[HIV infection. Zidovudine and 2',3'-dideoxycytidine in AIDS].
Topics: Acquired Immunodeficiency Syndrome; Dideoxynucleosides; Drug Administration Schedule; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine | 1988 |
Pharmacokinetics of 2',3'-dideoxycytidine in patients with AIDS and related disorders.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Antiviral Agents; Biological Availability; Chromatography, High Pressure Liquid; Dideoxynucleosides; Humans; Injections, Intravenous; Zalcitabine; Zidovudine | 1988 |
Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT).
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Deoxycytidine; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; HIV; Humans; Male; Middle Aged; Thymidine; Zalcitabine; Zidovudine | 1988 |