Page last updated: 2024-08-22

zalcitabine and ARC

zalcitabine has been researched along with ARC in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19908 (27.59)18.7374
1990's21 (72.41)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cameron, J; Cammack, N; Cooley, TP; Gu, Z; Hirst, HM; McCaffrey, R; Montaner, JS; Ruedy, J; Salomon, H; Wainberg, MA1
Lissen, E1
Khoo, SH; Wilkins, EG1
Dormont, J1
Antoniskis, D; Arezzo, J; Bigley, J; Bozzette, SA; Fischl, MA; Gelb, LD; Gocke, DJ; Grieco, MH; Hirsch, MS; Hyslop, NE; Leedom, JM; Lim, L; LoFaro, ML; McKinley, GF; Merigan, TC; Murphy, RL; Pettinelli, CB; Pottage, JC; Powderly, WG; Ray, G; Reed, N; Richman, DD; Schaumburg, HH; Simon, G; Skowron, G; Soo, W; Spector, SA; Sperber, SJ; Uttamchandani, RB; Zachary, J1
Arduino, JM; Chung, R; Crumpacker, CS; Hammer, SM; Japour, AJ; Lane, J; Mayers, DL; McLeod, GX; Reichman, R; Wagner, KF1
Broder, S; Gao, WY; Johns, DG; Mitsuya, H; Shirasaka, T1
French, MA; Martinez, OP1
Brawley, O; Broder, S; Cohen, RB; Nguyen, BY; Pluda, JM; Shay, LE; Venzon, DJ; Whitcup, SM; Wyvill, KM; Yarchoan, R1
Holazo, AA; Limjuco, R; Massarella, JW; Min, B; Nazareno, LA; Passe, S; Twardy, SK1
Boucher, CA; Cammack, N; Hill, A; Ingrand, D; Loveday, C; Robert, C; Weber, J1
Gries, JM; Jacobson, M; Sheiner, LB; Troconiz, IF; Verotta, D1
Töglhofer, W1
Mahler, W1
Clifford, DB; Klebert, MK; Powderly, WG1
Dunton, AW; Fukuda, EK; Gustavson, LE; Rubio, FA1
Merigan, TC; Skowron, G2
Fischl, MA; Meng, TC; Richman, DD1
Darby, G; Larder, BA; Richman, DD1
Bozzette, SA; Fischl, M; Hirsch, M; Merigan, TC; Pettinelli, C; Richman, D; Schooley, R; Skowron, G; Soo, W; Uttamchandani, R1
Ganser, A; Greher, J; Hoelzer, D; Staszewski, S; Völkers, B1
Broder, S; Dalakas, M; Dubinsky, RM; Yarchoan, R1
Allain, JP; Dubinsky, R; Fischl, MA; Klecker, RW; McAtee, N; McNeely, MC; Perno, CF; Thomas, RV; Wills, RJ; Yarchoan, R1
Offerhaus, L1

Reviews

6 review(s) available for zalcitabine and ARC

ArticleYear
[Anti-HIV therapy (1987-1994): from nothing to confusion].
    Medicina clinica, 1995, Apr-01, Volume: 104, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Time Factors; Zalcitabine; Zidovudine

1995
Controversies in anti-retroviral therapy of adults.
    The Journal of antimicrobial chemotherapy, 1995, Volume: 35, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; AIDS-Related Complex; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Drug Tolerance; HIV Infections; HIV-1; Humans; Zalcitabine; Zidovudine

1995
Future treatment strategies in HIV infection.
    AIDS (London, England), 1994, Volume: 8 Suppl 3

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Antiviral Agents; Biomarkers; CD4 Lymphocyte Count; Didanosine; Forecasting; HIV Infections; Humans; Zalcitabine; Zidovudine

1994
Safety and tolerance of dideoxycytidine as a single agent. Results of early-phase studies in patients with acquired immunodeficiency syndrome (AIDS) or advanced AIDS-related complex. Study Group of the AIDS Clinical Trials Group of the National Institute
    The American journal of medicine, 1990, May-21, Volume: 88, Issue:5B

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Drug Evaluation; Drug Tolerance; Gene Products, gag; HIV Antigens; HIV Core Protein p24; HIV-1; Humans; Viral Core Proteins; Zalcitabine

1990
Alternating and intermittent regimens of zidovudine (3'-azido-3'-deoxythymidine) and dideoxycytidine (2',3'-dideoxycytidine) in the treatment of patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex.
    The American journal of medicine, 1990, May-21, Volume: 88, Issue:5B

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Clinical Protocols; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Zalcitabine; Zidovudine

1990
AIDS Clinical Trials Group: phase I/II study of combination 2',3'-dideoxycytidine and zidovudine in patients with acquired immunodeficiency syndrome (AIDS) and advanced AIDS-related complex.
    The American journal of medicine, 1990, May-21, Volume: 88, Issue:5B

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Clinical Protocols; Drug Evaluation; Drug Therapy, Combination; Humans; Zalcitabine; Zidovudine

1990

Trials

11 trial(s) available for zalcitabine and ARC

ArticleYear
Development of HIV-1 resistance to (-)2'-deoxy-3'-thiacytidine in patients with AIDS or advanced AIDS-related complex.
    AIDS (London, England), 1995, Volume: 9, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; AIDS-Related Complex; Base Sequence; DNA Primers; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Female; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Lamivudine; Male; Molecular Sequence Data; Mutation; Phenotype; Proviruses; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Zalcitabine

1995
Alternating and intermittent regimens of zidovudine and dideoxycytidine in patients with AIDS or AIDS-related complex.
    Annals of internal medicine, 1993, Mar-01, Volume: 118, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; CD4-Positive T-Lymphocytes; Drug Administration Schedule; Drug Therapy, Combination; Female; Hematologic Diseases; HIV Core Protein p24; Humans; Leukocyte Count; Male; Peripheral Nervous System Diseases; Weight Gain; Zalcitabine; Zidovudine

1993
The effect of food on pharmacokinetics of zalcitabine in HIV-positive patients.
    Pharmaceutical research, 1995, Volume: 12, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Antiviral Agents; Biological Availability; Female; Food; HIV Infections; Humans; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zalcitabine

1995
Phase I/II study of 3TC (lamivudine) in HIV-positive, asymptomatic or mild AIDS-related complex patients: sustained reduction in viral markers. The Lamivudine European HIV Working Group.
    AIDS (London, England), 1995, Volume: 9, Issue:12

    Topics: Adult; AIDS-Related Complex; Antigen-Antibody Complex; Antiviral Agents; Dose-Response Relationship, Drug; HIV; HIV Core Protein p24; HIV Infections; HIV Seropositivity; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Viremia; Zalcitabine

1995
A pooled analysis of CD4 response to zidovudine and zalcitabine treatment in patients with AIDS and AIDS-related complex.
    Clinical pharmacology and therapeutics, 1997, Volume: 61, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Humans; Regression Analysis; Time Factors; Zalcitabine; Zidovudine

1997
A pilot study of the bioavailability and pharmacokinetics of 2',3'-dideoxycytidine in patients with AIDS or AIDS-related complex.
    Journal of acquired immune deficiency syndromes, 1990, Volume: 3, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; AIDS-Related Complex; Biological Availability; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Pilot Projects; Zalcitabine

1990
Alternating and intermittent regimens of zidovudine (3'-azido-3'-deoxythymidine) and dideoxycytidine (2',3'-dideoxycytidine) in the treatment of patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex.
    The American journal of medicine, 1990, May-21, Volume: 88, Issue:5B

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Clinical Protocols; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Zalcitabine; Zidovudine

1990
Circulating p24 antigen levels and responses to dideoxycytidine in human immunodeficiency virus (HIV) infections. A phase I and II study.
    Annals of internal medicine, 1989, Feb-01, Volume: 110, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; AIDS-Related Complex; Dideoxynucleosides; Drug Evaluation; Female; HIV Antigens; HIV Core Protein p24; Humans; Male; Random Allocation; Retroviridae Proteins; Zalcitabine

1989
FDA expands testing of anti-AIDS drugs.
    New York state journal of medicine, 1989, Volume: 89, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Dementia Complex; AIDS-Related Complex; Antiviral Agents; Clinical Trials as Topic; Didanosine; Humans; Infant; Infant, Newborn; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine

1989
New treatment being tested against AIDS and ARC.
    Oncology (Williston Park, N.Y.), 1987, Volume: 1, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Clinical Trials as Topic; HIV; Humans; Virus Replication; Zalcitabine

1987
[Azidothymidine and HIV infection].
    Nederlands tijdschrift voor geneeskunde, 1987, May-30, Volume: 131, Issue:22

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Drug Interactions; Humans; Thymidine; Zalcitabine; Zidovudine

1987

Other Studies

13 other study(ies) available for zalcitabine and ARC

ArticleYear
Dideoxynucleoside resistance emerges with prolonged zidovudine monotherapy. The RV43 Study Group.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Didanosine; Drug Resistance, Microbial; HIV Seropositivity; HIV-1; Humans; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Time Factors; Zalcitabine; Zidovudine

1994
Differential phosphorylation of azidothymidine, dideoxycytidine, and dideoxyinosine in resting and activated peripheral blood mononuclear cells.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:5

    Topics: 5'-Nucleotidase; Acquired Immunodeficiency Syndrome; Adenosine Kinase; AIDS-Related Complex; Chromatography, High Pressure Liquid; Deoxycytidine Kinase; Deoxyribonucleotides; Didanosine; HIV-1; Humans; Kinetics; Microbial Sensitivity Tests; Monocytes; Phosphorylation; Thymidine Kinase; Uridine Kinase; Zalcitabine; Zidovudine

1993
Acoustic neuropathy associated with zalcitabine-induced peripheral neuropathy.
    AIDS (London, England), 1993, Volume: 7, Issue:6

    Topics: AIDS-Related Complex; Hearing Loss, Sensorineural; Humans; Hypesthesia; Male; Middle Aged; Peripheral Nervous System Diseases; Tinnitus; Vestibulocochlear Nerve Diseases; Zalcitabine

1993
A pilot study of sequential therapy with zidovudine plus acyclovir, dideoxyinosine, and dideoxycytidine in patients with severe human immunodeficiency virus infection.
    The Journal of infectious diseases, 1993, Volume: 168, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; AIDS-Related Complex; Antigens, CD; Biomarkers; Body Weight; CD4 Antigens; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; HIV Core Protein p24; Humans; Male; Middle Aged; Pilot Projects; T-Lymphocyte Subsets; Time Factors; Zalcitabine; Zidovudine

1993
[New, in Austria registered specialty drugs. Hivid (2',3'-dideoxycytidine; ddC)].
    Wiener klinische Wochenschrift, 1992, Volume: 104, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Animals; Antiviral Agents; Austria; CD4-Positive T-Lymphocytes; Humans; Leukocyte Count; Zalcitabine; Zidovudine

1992
Treatment IND for dideoxycytidine.
    American family physician, 1991, Volume: 44, Issue:3

    Topics: AIDS-Related Complex; Clinical Protocols; Humans; United States; United States Food and Drug Administration; Zalcitabine

1991
[AIDS: initial results of combination therapy. AIDS and ARC--alternating or intermittent medication].
    Fortschritte der Medizin, 1991, Jan-15, Volume: 109, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; CD4 Antigens; Combined Modality Therapy; HIV; Humans; Immunotherapy, Adoptive; Interferon Type I; Recombinant Proteins; Zalcitabine; Zidovudine

1991
Expanded access for AIDS drug.
    Iowa medicine : journal of the Iowa Medical Society, 1991, Volume: 81, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Humans; Zalcitabine

1991
Ototoxicity associated with dideoxycytidine.
    Lancet (London, England), 1990, May-05, Volume: 335, Issue:8697

    Topics: Adult; AIDS-Related Complex; Drug Administration Schedule; Hearing Loss, Sensorineural; Hearing Tests; Humans; Male; Zalcitabine

1990
HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy.
    Science (New York, N.Y.), 1989, Mar-31, Volume: 243, Issue:4899

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Dideoxynucleosides; Drug Resistance; Foscarnet; HeLa Cells; HIV; HIV Core Protein p24; Humans; Microbial Sensitivity Tests; Phosphonoacetic Acid; Retroviridae Proteins; Reverse Transcriptase Inhibitors; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine

1989
Inhibitory effect of azidothymidine, 2'-3'-dideoxyadenosine, and 2'-3'-dideoxycytidine on in vitro growth of hematopoietic progenitor cells from normal persons and from patients with AIDS.
    Experimental hematology, 1989, Volume: 17, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Bone Marrow; Colony-Forming Units Assay; Deoxyribonucleosides; Dideoxyadenosine; Dideoxynucleosides; Dose-Response Relationship, Drug; Growth Inhibitors; Hematopoiesis; Hematopoietic Stem Cells; Humans; Zalcitabine; Zidovudine

1989
Reversible axonal neuropathy from the treatment of AIDS and related disorders with 2',3'-dideoxycytidine (ddC).
    Muscle & nerve, 1989, Volume: 12, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Axons; Dose-Response Relationship, Drug; Electromyography; Humans; Pain; Peripheral Nervous System Diseases; Zalcitabine

1989
Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT).
    Lancet (London, England), 1988, Jan-16, Volume: 1, Issue:8577

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Deoxycytidine; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; HIV; Humans; Male; Middle Aged; Thymidine; Zalcitabine; Zidovudine

1988