Page last updated: 2024-08-22

zalcitabine and AIDS Seroconversion

zalcitabine has been researched along with AIDS Seroconversion in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's25 (89.29)18.2507
2000's2 (7.14)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Colan, SD; Mittleman, MA; Oleske, JM; Patel, K; Seage, GR; Van Dyke, RB1
Cauda, R; Donelli, G; Landay, AL; Lucia, MB; Malorni, W; Ortona, L1
Daniel, MJ; Donn, KH; Evans, GL; Hall, ST; Harker, AJ; Hussey, EK1
Craib, KJ; Hogg, RS; Montaner, JS; O'Shaughnessy, MV; Schechter, MT; Strathdee, SA1
Evans, GL; Harker, AJ; Hawley, AE; Morris, DM1
Arduino, JM; Chung, R; Crumpacker, CS; Hammer, SM; Japour, AJ; Lane, J; Mayers, DL; McLeod, GX; Reichman, R; Wagner, KF1
Chou, TC; Hirsch, MS; Merrill, DP; Moonis, M1
Boucher, CA; Cammack, N; Hill, A; Ingrand, D; Loveday, C; Robert, C; Weber, J1
Detels, R; Graham, NM; Hoover, DR; Mellors, JW; Park, LP; Phair, JP; Saah, AJ; Stein, DS1
Eron, JJ; Hussey, EK; Martin, D; Moore, KH; Mydlow, PK; Raasch, RH; Yuen, GJ1
Cooper, DA; Harrigan, PR; Kinghorn, I; Lange, JM; Larder, BA; Lavelle, J; Lefkowitz, L; McKinnis, R; Moore, M; Mulder, JW; Pennington, KN; Ramirez-Ronda, C; Rooney, JF; Schooley, RT; St Clair, M; Steel, H1
Massarella, JW; Min, B; Nazareno, LA; Passe, S1
Bloor, S; Harrigan, PR; Kemp, SD; Kinghorn, I; Kohli, A; Larder, BA; Nájera, I1
Bloor, S; Harrigan, PR; Kemp, SD; Kohli, A; Lange, JM; Larder, BA; Pennington, KN; Schooley, RT; St Clair, MH1
Blum, AS; Cornblath, DR; Dal Pan, GJ; Feinberg, J; Mayjo, K; McArthur, JC; Raines, C1
Albrecht, H; Fenner, T; Greten, H; Lichtenberg, G; Stellbrink, HJ; Thiele, HG; van Lunzen, J; Zöller, B1
Bechtel, LM; Starich, GH; Whitfield, RM1
Berthelot, P; Frésard, A; Guglielminotti, C; Lucht, F; Perrot, JL1
Kempf-Durepaire, G; Krantz, V; Lang, JM; Nicolle, M; Partisani, M; Rey, D; Schmitt, AC; Schmitt, MP1
AbdelHameed, MH; Dorr, A; Griffy, K; Jung, D; Teitelbaum, P1
La Seta Catamancio, S; Parker, D; Rusconi, S; Sheridan, F1
Arendt, G; Hefter, H; Theisen, A; von Giesen, HJ1
Harris, R; Kellagher, A; Moyle, GJ; Walker, M; Warburg, M1
Arnó, A; Balaguer, M; Camafort, M; Cervantes, M; Clotet, B; Colomer, J; Gutiérrez, C; Ibáñez, A; Peraire, J; Richart, C; Ruiz, L; Vidal, F; Villalonga, C1
Antunes, F; Bouza, E; Harris, R; Moyle, GJ; Smith, D; Walker, M; Warburg, M1
Molina, JM1
Lane, HC1

Reviews

1 review(s) available for zalcitabine and AIDS Seroconversion

ArticleYear
Current status of therapy for human immunodeficiency virus type 1.
    Current opinion in immunology, 1992, Volume: 4, Issue:4

    Topics: CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; Didanosine; Drug Resistance; HIV Infections; HIV Seropositivity; HIV-1; Humans; T-Lymphocytes, Helper-Inducer; Zalcitabine; Zidovudine

1992

Trials

13 trial(s) available for zalcitabine and AIDS Seroconversion

ArticleYear
Interspecies scaling and pharmacokinetic parameters of 3TC in humans.
    Journal of clinical pharmacology, 1994, Volume: 34, Issue:10

    Topics: Animals; Antiviral Agents; Body Weight; Cross-Over Studies; Dogs; HIV Seropositivity; Humans; Infusions, Intravenous; Lamivudine; Male; Rats; Reverse Transcriptase Inhibitors; Species Specificity; Zalcitabine

1994
Phase I/II study of 3TC (lamivudine) in HIV-positive, asymptomatic or mild AIDS-related complex patients: sustained reduction in viral markers. The Lamivudine European HIV Working Group.
    AIDS (London, England), 1995, Volume: 9, Issue:12

    Topics: Adult; AIDS-Related Complex; Antigen-Antibody Complex; Antiviral Agents; Dose-Response Relationship, Drug; HIV; HIV Core Protein p24; HIV Infections; HIV Seropositivity; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Viremia; Zalcitabine

1995
Survival in HIV-infected patients who have received zidovudine: comparison of combination therapy with sequential monotherapy and continued zidovudine monotherapy. Multicenter AIDS Cohort Study Group.
    Annals of internal medicine, 1996, Jun-15, Volume: 124, Issue:12

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Drug Administration Schedule; Drug Therapy, Combination; HIV Seropositivity; Humans; Longitudinal Studies; Male; Proportional Hazards Models; Zalcitabine; Zidovudine

1996
Pharmacokinetics of lamivudine administered alone and with trimethoprim-sulfamethoxazole.
    Clinical pharmacology and therapeutics, 1996, Volume: 59, Issue:5

    Topics: Administration, Oral; Adult; Analysis of Variance; Anti-Infective Agents; Antiviral Agents; CD4 Lymphocyte Count; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Interactions; Female; HIV Seropositivity; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Trimethoprim, Sulfamethoxazole Drug Combination; Zalcitabine

1996
Virologic and immunologic benefits of initial combination therapy with zidovudine and zalcitabine or didanosine compared with zidovudine monotherapy. Wellcome Resistance Study Collaborative Group.
    The Journal of infectious diseases, 1996, Volume: 173, Issue:6

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Male; Middle Aged; Phenotype; RNA, Viral; Zalcitabine; Zidovudine

1996
The effect of probenecid on the pharmacokinetics of zalcitabine in HIV-positive patients.
    Pharmaceutical research, 1996, Volume: 13, Issue:3

    Topics: Administration, Oral; Adult; Antiviral Agents; Cross-Over Studies; Drug Administration Schedule; Drug Interactions; Female; Half-Life; HIV Seropositivity; Humans; Kidney Tubules; Male; Middle Aged; Probenecid; Uricosuric Agents; Zalcitabine

1996
Human immunodeficiency virus type 1 drug susceptibility during zidovudine (AZT) monotherapy compared with AZT plus 2',3'-dideoxyinosine or AZT plus 2',3'-dideoxycytidine combination therapy. The protocol 34,225-02 Collaborative Group.
    Journal of virology, 1996, Volume: 70, Issue:9

    Topics: Antigens, CD; Antiviral Agents; CD4 Antigens; Coculture Techniques; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HeLa Cells; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Lymphocytes; Microbial Sensitivity Tests; Phenotype; Point Mutation; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine

1996
Low-dose zalcitabine-related toxic neuropathy: frequency, natural history, and risk factors.
    Neurology, 1996, Volume: 46, Issue:4

    Topics: Adult; Cohort Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; HIV Seropositivity; Humans; Incidence; Male; Middle Aged; Nervous System Diseases; Risk Factors; Sensation Disorders; Survival Analysis; Zalcitabine

1996
Rapid plasma virus and CD4+ T-cell turnover in HIV-1 infection: evidence for an only transient interruption by treatment.
    AIDS (London, England), 1996, Volume: 10, Issue:8

    Topics: Adult; Anti-HIV Agents; beta 2-Microglobulin; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV Core Protein p24; HIV Seropositivity; HIV-1; Humans; Kinetics; Male; RNA, Viral; Saquinavir; Viral Load; Zalcitabine; Zidovudine

1996
The pharmacokinetics and safety profile of oral ganciclovir combined with zalcitabine or stavudine in asymptomatic HIV- and CMV-seropositive patients.
    Journal of clinical pharmacology, 1999, Volume: 39, Issue:5

    Topics: Administration, Oral; Anti-HIV Agents; Antiviral Agents; Area Under Curve; Cross-Over Studies; Cytomegalovirus Retinitis; Drug Interactions; Female; Ganciclovir; HIV Seropositivity; Humans; Male; Stavudine; Zalcitabine

1999
Therapeutic effects of nucleoside analogues on psychomotor slowing in HIV infection.
    AIDS (London, England), 2001, Mar-09, Volume: 15, Issue:4

    Topics: Adult; Anti-HIV Agents; Central Nervous System Diseases; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Middle Aged; Motor Skills; Stavudine; Zalcitabine; Zidovudine

2001
Zidovudine monotherapy versus zidovudine plus zalcitabine combination therapy in HIV-positive persons with CD4 cell counts 300-500 cells/mm3: a double-blind controlled trial. The M50003 Study Group Coordinating and Writing Committee.
    Antiviral therapy, 1997, Volume: 2, Issue:4

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV Seropositivity; Humans; Male; Middle Aged; Quality of Life; Zalcitabine; Zidovudine

1997
[Efficacy and tolerance of dideoxynucleosides in HIV infection].
    Pathologie-biologie, 1992, Volume: 39, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; HIV Seropositivity; Humans; Zalcitabine; Zidovudine

1992

Other Studies

14 other study(ies) available for zalcitabine and AIDS Seroconversion

ArticleYear
The impact of HAART on cardiomyopathy among children and adolescents perinatally infected with HIV-1.
    AIDS (London, England), 2012, Oct-23, Volume: 26, Issue:16

    Topics: Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cardiomyopathies; Cardiotonic Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Cohort Studies; Digoxin; Female; Follow-Up Studies; HIV Seropositivity; Humans; Infant; Infectious Disease Transmission, Vertical; Male; Pregnancy; Prenatal Exposure Delayed Effects; Proportional Hazards Models; Prospective Studies; Treatment Outcome; United States; Zalcitabine; Zidovudine

2012
Transmembrane P-glycoprotein (P-gp/P-170) in HIV infection: analysis of lymphocyte surface expression and drug-unrelated function.
    AIDS research and human retroviruses, 1995, Volume: 11, Issue:8

    Topics: Adult; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Didanosine; Female; HIV Seropositivity; Humans; Immunophenotyping; Interleukin-2; Lymphocyte Activation; Lymphocytes; Male; Phytohemagglutinins; Zalcitabine; Zidovudine

1995
Lower socioeconomic status and shorter survival following HIV infection.
    Lancet (London, England), 1994, Oct-22, Volume: 344, Issue:8930

    Topics: Acquired Immunodeficiency Syndrome; Adult; British Columbia; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Health Services; HIV Infections; HIV Seropositivity; Homosexuality, Male; Humans; Income; Male; Pneumonia, Pneumocystis; Regression Analysis; Socioeconomic Factors; Survival Rate; Zalcitabine; Zidovudine

1994
High-performance liquid chromatographic assay for 2'-deoxy-3'-thiacytidine in human serum.
    Journal of chromatography. B, Biomedical applications, 1994, Jul-01, Volume: 657, Issue:1

    Topics: Antiviral Agents; Autoanalysis; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV Seropositivity; Hot Temperature; Humans; Lamivudine; Quality Control; Sensitivity and Specificity; Zalcitabine

1994
Dideoxynucleoside resistance emerges with prolonged zidovudine monotherapy. The RV43 Study Group.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Didanosine; Drug Resistance, Microbial; HIV Seropositivity; HIV-1; Humans; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Time Factors; Zalcitabine; Zidovudine

1994
Lamivudine or stavudine in two- and three-drug combinations against human immunodeficiency virus type 1 replication in vitro.
    The Journal of infectious diseases, 1996, Volume: 173, Issue:2

    Topics: Antiviral Agents; Drug Combinations; Drug Synergism; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Virus Replication; Zalcitabine

1996
Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility.
    Journal of virology, 1996, Volume: 70, Issue:9

    Topics: Antiviral Agents; Codon; Drug Therapy, Combination; Genetic Variation; HeLa Cells; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Lamivudine; Point Mutation; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Virus Replication; Zalcitabine; Zidovudine

1996
The impact of ethanol and Marinol/marijuana usage on HIV+/AIDS patients undergoing azidothymidine, azidothymidine/dideoxycytidine, or dideoxyinosine therapy.
    Alcoholism, clinical and experimental research, 1997, Volume: 21, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Alcohol Drinking; Amylases; Anti-HIV Agents; Appetite Stimulants; CD4 Lymphocyte Count; Didanosine; Dronabinol; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Seropositivity; Humans; Liver Function Tests; Male; Marijuana Smoking; Middle Aged; Pancreatitis, Alcoholic; Zalcitabine; Zidovudine

1997
Dramatic cutaneous psoriasis improvement in a patient with the human immunodeficiency virus treated with 2',3'-dideoxy,3'-thyacytidine [correction of 2',3'-dideoxycytidine] and ritonavir.
    Archives of dermatology, 1997, Volume: 133, Issue:4

    Topics: Adult; Anti-HIV Agents; HIV Seropositivity; Humans; Male; Psoriasis; Remission Induction; Ritonavir; Zalcitabine

1997
[Weak antiviral effect of changing two nucleoside analogues combined with antiretroviral agents. 3TC and d4T after ZDU and ddi or ddc].
    Presse medicale (Paris, France : 1983), 1998, Feb-28, Volume: 27, Issue:8

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Retrospective Studies; Stavudine; Viral Load; Zalcitabine; Zidovudine

1998
A genotypic analysis of patients receiving Zidovudine with either Lamivudine, Didanosine or Zalcitabine dual therapy using the LiPA point mutation assay to detect genotypic variation at codons 41, 69, 70, 74, 184 and 215.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2000, Volume: 19, Issue:3

    Topics: Anti-HIV Agents; Codon; Didanosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Genotype; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Nucleic Acid Hybridization; Point Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine

2000
Safety and activity of zalcitabine and zidovudine combination in HIV-positive people with CD4 cell counts < or = 300 cells/mm3. The Roche M50002 Study Group.
    Antiviral therapy, 1996, Volume: 1, Issue:3

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Seropositivity; Humans; Male; Middle Aged; Zalcitabine; Zidovudine

1996
Immunological and virological activity of zalcitabine and zidovudine in combination in HIV-positive people with CD4 cell counts of between 200-500 cells/mm3.
    Antiviral therapy, 1997, Volume: 2, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Seropositivity; Humans; RNA, Viral; Zalcitabine; Zidovudine

1997
Potent new AIDS drugs underscore promise of combination therapy.
    AIDS alert, 1996, Volume: 11, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Drug Approval; Drug Resistance; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Seropositivity; Humans; Isoquinolines; Lamivudine; Quinolines; Saquinavir; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine

1996