Page last updated: 2024-08-20

yohimbine and Drug Withdrawal Symptoms

yohimbine has been researched along with Drug Withdrawal Symptoms in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199011 (31.43)18.7374
1990's11 (31.43)18.2507
2000's9 (25.71)29.6817
2010's4 (11.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belluzzi, JD; Leslie, FM; Malagon, AM; Yasuda, D; Yuan, M; Zaveri, NT1
Edwards, S; Koob, GF; Park, PE; Schlosburg, JE; Schulteis, G; Vendruscolo, LF1
Leri, F; Minhas, M1
Braconi, S; Cannella, N; Ciccocioppo, R; Cippitelli, A; Demopulos, G; Gaitanaris, G; Heilig, M; Kallupi, M; Massi, M; Ruggeri, B; Somaini, L; Stopponi, S1
Hayashi, M; Hoshi, K; Ichihara, K; Nakai, T; Wakabayashi, H1
Aricioglu, F; Dulger, G; Ercil, E1
Aricioglu, F; Utkan, T1
Aviles, M; González-Cuello, A; Laorden, ML; Milanés, MV1
Campanella, S; Dan, B; Hanak, C; Meyvaert, A; Pelc, I; Streel, E; Verbanck, P1
Collier, HO; Tucker, JF1
Axelsson, KL; Rydell, EL1
Fersel, J; Melman, A; Weinstein, P1
Dwoskin, LP; Neal, BS; Sparber, SB1
Baeyens, JM; Barrios, M; Robles, I1
Black, JE; Heninger, GR; Kosten, TR; Malison, RT; McDougle, CJ; Price, LH; Zimmermann, RC1
Aley, KO; Levine, JD1
Hameedi, FA; Kosten, TR; Pearsall, HR; Rosen, MI; Woods, SW1
El-Kadi, AO; Sharif, SI1
Bhattacharya, SK; Chakrabarti, A; Satyan, KS1
Arad, MA; Dehpour, AR; Namiranian, K; Samini, M1
Charney, DS; Kosten, TR; Krystal, JH; Petrakis, IL; Southwick, SM; Stine, SM1
Fayaz-Dastgerdi, M; Homayoun, H; Khavandgar, S; Zarrindast, MR1
Azizi, MR; Dehpour, AR; Farahani, M; Javidan, AN; Namiranian, K; Sadr, SS1
Dunstan, R; Jackson, DM1
Colado, MI; Martin, MI1
Jhamandas, K; Penning, DH1
Garzón, J; Sánchez-Blázquez, P1
Martinelli, B; Morrone, LA; Severini, C; Valeri, P1
Elsworth, JD; Lewis, VO; Pivirotto, P; Redmond, DE; Roth, RH; Taylor, JR1
Chahl, LA1
Jonkman, FA; Man, PW; Thoolen, MJ; van Zwieten, PA1
Kulkarni, SK; Kunchandy, J1
Martinelli, B; Pimpinella, G; Severini, C; Valeri, P1
Idemudia, SO; Lal, H; Mathis, DA1
Brown, OM; DiStefano, PS1

Reviews

1 review(s) available for yohimbine and Drug Withdrawal Symptoms

ArticleYear
Sites and mechanisms of dependence in the myenteric plexus of guinea pig ileum.
    NIDA research monograph, 1984, Volume: 54

    Topics: Acetylcholine; Adenosine; Animals; Clonidine; Cyclic AMP; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Morphine; Morphine Dependence; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Pertussis Vaccine; Scopolamine; Substance P; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Yohimbine

1984

Trials

3 trial(s) available for yohimbine and Drug Withdrawal Symptoms

ArticleYear
Noradrenergic dysregulation during discontinuation of cocaine use in addicts.
    Archives of general psychiatry, 1994, Volume: 51, Issue:9

    Topics: Administration, Intranasal; Adult; Cocaine; Double-Blind Method; Female; Hospitalization; Humans; Hydrocortisone; Infusions, Intravenous; Insufflation; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Panic Disorder; Prospective Studies; Single-Blind Method; Substance Withdrawal Syndrome; Substance-Related Disorders; Yohimbine

1994
Dose dependent effects of yohimbine on methadone maintained patients.
    The American journal of drug and alcohol abuse, 1997, Volume: 23, Issue:2

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; In Vitro Techniques; Male; Methadone; Middle Aged; Naloxone; Narcotic Antagonists; Narcotics; Substance Withdrawal Syndrome; Substance-Related Disorders; Yohimbine

1997
Yohimbine-induced withdrawal and anxiety symptoms in opioid-dependent patients.
    Biological psychiatry, 2002, Apr-15, Volume: 51, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adult; Analgesics, Opioid; Anxiety; Blood Pressure; Double-Blind Method; Female; Humans; Hydrocortisone; Male; Methadone; Methoxyhydroxyphenylglycol; Opioid-Related Disorders; Substance Withdrawal Syndrome; Yohimbine

2002

Other Studies

31 other study(ies) available for yohimbine and Drug Withdrawal Symptoms

ArticleYear
The α3β4 nAChR partial agonist AT-1001 attenuates stress-induced reinstatement of nicotine seeking in a rat model of relapse and induces minimal withdrawal in dependent rats.
    Behavioural brain research, 2017, 08-30, Volume: 333

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Cholinergic Agonists; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oligopeptides; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Stress, Psychological; Substance Withdrawal Syndrome; Tobacco Use Disorder; Yohimbine

2017
Corticotropin-releasing factor (CRF) and α 2 adrenergic receptors mediate heroin withdrawal-potentiated startle in rats.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:8

    Topics: Acoustic Stimulation; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analysis of Variance; Animals; Clonidine; Conditioning, Operant; Corticotropin-Releasing Hormone; Disease Models, Animal; Heroin; Male; Narcotics; Norepinephrine; Psychoacoustics; Pyrimidines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reflex, Startle; Self Administration; Substance Withdrawal Syndrome; Time Factors; Yohimbine

2013
The effect of heroin dependence on resumption of heroin self-administration in rats.
    Drug and alcohol dependence, 2014, May-01, Volume: 138

    Topics: Animals; Dose-Response Relationship, Drug; Extinction, Psychological; Heroin; Heroin Dependence; Male; Naloxone; Rats; Reinforcement Schedule; Self Administration; Substance Withdrawal Syndrome; Yohimbine

2014
Activation of nuclear PPARγ receptors by the antidiabetic agent pioglitazone suppresses alcohol drinking and relapse to alcohol seeking.
    Biological psychiatry, 2011, Apr-01, Volume: 69, Issue:7

    Topics: Adrenergic alpha-2 Receptor Antagonists; Alcohol Drinking; Alcohols; Analysis of Variance; Anilides; Animals; Behavior, Animal; Blood Glucose; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Food Preferences; Gene Expression Regulation; Hypoglycemic Agents; Male; Pioglitazone; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Self Administration; Substance Withdrawal Syndrome; Thiazolidinediones; Yohimbine

2011
Noradrenaline release in rat locus coeruleus is regulated by both opioid and alpha(2) -adrenoceptors.
    Pharmacological research, 2002, Volume: 45, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Injections, Intraventricular; Locus Coeruleus; Male; Microdialysis; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Substance Withdrawal Syndrome; Yohimbine

2002
Agmatine inhibits naloxone-induced contractions in morphine-dependent Guinea pig ileum.
    Annals of the New York Academy of Sciences, 2003, Volume: 1009

    Topics: Adrenergic alpha-Antagonists; Agmatine; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Idazoxan; Ileum; Male; Morphine; Morphine Dependence; Muscle Contraction; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Yohimbine

2003
Inhibitory effect of harmane on morphine-dependent Guinea pig ileum.
    Annals of the New York Academy of Sciences, 2003, Volume: 1009

    Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Guinea Pigs; Harmine; Idazoxan; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle Contraction; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Yohimbine

2003
Changes in c-fos expression in the rat heart during morphine withdrawal. Involvement of alpha2-adrenoceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:1

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Blotting, Western; Body Weight; Drug Administration Schedule; Drug Therapy, Combination; Gene Expression; Genes, fos; Heart Ventricles; Immunohistochemistry; Injections, Subcutaneous; Male; Morphine; Myocytes, Cardiac; Naloxone; Normetanephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Time Factors; Yohimbine

2004
A pharmacological modulation of opiate withdrawal using an up-/down-regulation of the noradrenergic system in opiate-dependent rats.
    The international journal of neuropsychopharmacology, 2006, Volume: 9, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Male; Morphine; Morphine Dependence; Narcotics; Norepinephrine; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Up-Regulation; Yohimbine

2006
Adrenaline toxicity in mice: sensitization of alpha 1 adrenoreceptors by nitroglycerin.
    Acta pharmacologica et toxicologica, 1984, Volume: 55, Issue:1

    Topics: Angina Pectoris; Animals; Coronary Vessels; Epinephrine; Humans; Male; Mice; Mice, Inbred Strains; Nitroglycerin; Prazosin; Receptors, Adrenergic, alpha; Substance Withdrawal Syndrome; Yohimbine

1984
Further studies on the effect of chronic alpha-methyldopa administration upon the central nervous system and sexual function in male rats.
    The Journal of urology, 1984, Volume: 132, Issue:4

    Topics: Animals; Carbidopa; Central Nervous System; Erectile Dysfunction; Humans; Libido; Male; Methyldopa; Norepinephrine; Penis; Rats; Reflex; Sexual Behavior, Animal; Substance Withdrawal Syndrome; Yohimbine

1984
Yohimbine exacerbates and clonidine attenuates acute morphine withdrawal in rats.
    European journal of pharmacology, 1983, Jun-03, Volume: 90, Issue:2-3

    Topics: Animals; Behavior, Animal; Clonidine; Drug Interactions; Humans; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reinforcement Schedule; Substance Withdrawal Syndrome; Yohimbine

1983
Role of L-type calcium channels on yohimbine-precipitated clonidine withdrawal in vivo and in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Behavior, Animal; Calcium Channels; Clonidine; Diltiazem; Dose-Response Relationship, Drug; Drug Implants; Female; Ileum; In Vitro Techniques; Isomerism; Mice; Muscle Contraction; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Verapamil; Yohimbine

1993
Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jan-15, Volume: 17, Issue:2

    Topics: Adenosine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Analgesics, Opioid; Animals; Clonidine; Dinoprostone; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hyperalgesia; Male; Models, Biological; Naloxone; Narcotic Antagonists; Oligonucleotides, Antisense; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Receptors, Purinergic P1; Second Messenger Systems; Substance Withdrawal Syndrome; Substance-Related Disorders; Xanthines; Yohimbine

1997
The influence of chronic treatment with clonidine, yohimbine and idazoxan on morphine withdrawal.
    Psychopharmacology, 1997, Volume: 132, Issue:1

    Topics: Adrenergic Agents; Animals; Clonidine; Drug Interactions; Idazoxan; Male; Mice; Morphine; Narcotics; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Yohimbine

1997
Anxiogenic action of caffeine: an experimental study in rats.
    Journal of psychopharmacology (Oxford, England), 1997, Volume: 11, Issue:3

    Topics: Animals; Anxiety; Caffeine; Central Nervous System Stimulants; Drug Tolerance; Exploratory Behavior; Male; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Social Behavior; Substance Withdrawal Syndrome; Yohimbine

1997
Clonidine attenuates naloxone-induced opioid-withdrawal syndrome in cholestatic mice.
    Pharmacology & toxicology, 2001, Volume: 89, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cholestasis; Clonidine; Disease Models, Animal; Male; Mice; Naloxone; Narcotic Antagonists; Opioid Peptides; Substance Withdrawal Syndrome; Yohimbine

2001
The effects of simultaneous administration of alpha(2) -adrenergic agents with L-NAME or L-arginine on the development and expression of morphine dependence in mice.
    Behavioural pharmacology, 2002, Volume: 13, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arginine; Clonidine; Enzyme Inhibitors; Male; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Substance Withdrawal Syndrome; Yohimbine

2002
Lithium inhibits the development of physical dependence to clonidine in mice.
    Pharmacology & toxicology, 2002, Volume: 90, Issue:2

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Animals; Clonidine; Injections, Intraperitoneal; Lithium; Male; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Substance-Related Disorders; Yohimbine

2002
Further evidence for a change in central alpha-adrenergic receptor sensitivity after withdrawal from long-term haloperidol treatment.
    Naunyn-Schmiedeberg's archives of pharmacology, 1978, Volume: 303, Issue:2

    Topics: Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Drug Interactions; Haloperidol; Humans; Male; Methyltyrosines; Mice; Motor Activity; Phenoxybenzamine; Phentolamine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Substance Withdrawal Syndrome; Yohimbine

1978
Effects of opioid and alpha 2-adrenoceptor agonists on the isolated ileum of morphine-dependent guinea-pigs during withdrawal and after clonidine treatment.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Drug Tolerance; Electric Stimulation; Guinea Pigs; Ileum; Male; Morphine; Morphine Dependence; Myenteric Plexus; Naloxone; Narcotics; Neuromuscular Junction; Substance Withdrawal Syndrome; Yohimbine

1992
Yohimbine-precipitated clonidine withdrawal: an experimental model of the antihypertensive drug withdrawal syndrome.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:6

    Topics: Animals; Antihypertensive Agents; Atropine; Blood Pressure; Central Nervous System; Choline; Clonidine; Ganglia, Sympathetic; Ganglionic Blockers; Heart Rate; Hexamethonium; Hexamethonium Compounds; Injections, Intravenous; Injections, Intraventricular; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Yohimbine

1992
alpha N-acetyl human beta-endorphin-(1-31) alleviates the morphine withdrawal syndrome in rodents: a comparative study with clonidine.
    Life sciences, 1992, Volume: 50, Issue:26

    Topics: Animals; beta-Endorphin; Clonidine; Disease Models, Animal; Male; Mice; Morphine; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Yohimbine

1992
Reproducible withdrawal contractions of isolated guinea-pig ileum after brief morphine exposure: effects of clonidine and nifedipine.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nifedipine; Substance Withdrawal Syndrome; Yohimbine

1990
Yohimbine co-treatment during chronic morphine administration attenuates naloxone-precipitated withdrawal without diminishing tail-flick analgesia in rats.
    Psychopharmacology, 1991, Volume: 103, Issue:3

    Topics: Analgesics; Animals; Behavior, Animal; Drug Implants; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reaction Time; Substance Withdrawal Syndrome; Yohimbine

1991
The properties of the clonidine withdrawal response of guinea-pig isolated ileum.
    British journal of pharmacology, 1985, Volume: 85, Issue:2

    Topics: Animals; Atropine; Clonidine; Drug Interactions; Enkephalin, Methionine; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Muscle Contraction; Norepinephrine; Phentolamine; Substance P; Substance Withdrawal Syndrome; Yohimbine

1985
Location of the mechanism of the clonidine withdrawal tachycardia in rats.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:8

    Topics: Animals; Blood Pressure; Clonidine; Injections, Intraventricular; Injections, Subcutaneous; Male; Oxymetazoline; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Tachycardia; Time Factors; Yohimbine

1985
Reversal by alpha-2 agonists of diazepam withdrawal hyperactivity in rats.
    Psychopharmacology, 1986, Volume: 90, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Clonidine; Diazepam; Guanfacine; Guanidines; Male; Motor Activity; Phenylacetates; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Yohimbine

1986
Effects of dapiprazole, clonidine and yohimbine on the development of dependence and withdrawal behaviour in mice.
    Drug and alcohol dependence, 1989, Volume: 23, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Clonidine; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Morphine Dependence; Naloxone; Piperazines; Substance Withdrawal Syndrome; Triazoles; Yohimbine

1989
Enhancement of a diazepam withdrawal symptom by bicuculline and yohimbine.
    Neuropharmacology, 1987, Volume: 26, Issue:12

    Topics: Animals; Bicuculline; Diazepam; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; Male; Rats; Substance Withdrawal Syndrome; Yohimbine

1987
Biochemical correlates of morphine withdrawal. 2. Effects of clonidine.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:2

    Topics: Adrenal Glands; Animals; Clonidine; Denervation; Dose-Response Relationship, Drug; Epinephrine; Humans; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Yohimbine

1985