Page last updated: 2024-08-20

yohimbine and Allodynia

yohimbine has been researched along with Allodynia in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (8.00)18.2507
2000's18 (36.00)29.6817
2010's24 (48.00)24.3611
2020's4 (8.00)2.80

Authors

AuthorsStudies
Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG1
Fujimoto, Y; Juri, T; Mori, T; Nishikawa, K; Suehiro, K1
Choi, GJ; Kang, H; Kwon, JW; Lee, OH1
Chen, H; Chen, SR; Huang, Y; Pan, HL1
Matsuura, W; Nakamoto, K; Tokuyama, S1
Aktumsek, A; Antoniolli, AR; Araújo, AAS; Araújo-Filho, HG; Brito, RG; Coutinho, HDM; Lucchesi, A; Menezes, IRA; Menezes, PP; Quintans, JSS; Quintans-Júnior, LJ; Santos, PL; Scotti, L; Scotti, MT; Siqueira-Lima, PS; Zengin, G1
Lin, B; Lu, Y; Zhong, J1
Castor, MGME; Duarte, IDG; Guzzo, LS; Klein, A; Petrocchi, JA; Romero, TRL; Soares Santos, RR1
Hickey, L; Hughes, SW; Hulse, RP; Lumb, BM; Pickering, AE1
Barry, DM; Du, JQ; Huo, FQ; Qu, CL; Tang, JS; Xu, FY; Xu, WJ; Zhao, Y; Zhu, JX1
Bong, DJ; Han, SD; Oh, B; Roh, DH; Yeo, JH; Yoon, SY1
Christoph, T; De Vry, J; Schröder, W; Tallarida, RJ; Tzschentke, TM1
Caselli, G; Ferrari, F; Lanza, M; Menghetti, I; Tremolada, D1
Abed, A; Banafshe, HR; Hajhashemi, V; Mesdaghinia, A; Minaiyan, M1
Kimura, M; Sakai, A; Sakamoto, A; Suzuki, H1
Castor, MG; Duarte, ID; Romero, TR; Santos, RA1
Higuchi, H; Honda, Y; Ishii-Maruhama, M; Maeda, S; Matsuoka, Y; Miyawaki, T; Morimatsu, H; Tomoyasu, Y; Yabuki-Kawase, A1
Batisti, AP; Carlesso, MG; Donatello, N; dos Santos, AR; Emer, AA; Martins, DF; Mazzardo-Martins, L; Micke, GA; Piovezan, AP; Pizzolatti, MG; Venzke, D1
Beitz, AJ; Kim, SJ; Kwon, SK; Lee, JH; Roh, DH; Yeo, JH; Yoon, SY1
Bahr, MH; Hamza, M; Masoud, SI; Saad, SS1
Banerjee, T; Holden, JE; Jeong, Y; Wagner, M1
Drummond, PD1
de Castro Perez, A; de Francischi, JN; Gama Duarte, ID; Romero, TR1
An, K; Arita, H; Hanaoka, K; Hayashida, M; Huang, W; Shu, H; Zhang, L1
Chen, HS; He, X; Qu, F; Wang, Y; Wen, WW1
Hagiwara, S; Iwasaka, H; Noguchi, T; Okuda, K; Takatani, J; Takeshima, N; Uchino, T1
Ambriz-Tututi, M; Drucker-Colín, R; Sánchez-González, V1
Dong, R; Feng, X; Li, W; Liu, J; Wang, H; Xu, J; Yu, B; Zhang, F1
Micov, AM; Paranos, SLj; Stepanović-Petrović, RM; Tomić, MA1
Cidral-Filho, FJ; Martins, DF; Mazzardo-Martins, L; Santos, AR; Stramosk, J1
Bujalska-Zadrożny, M; Cegielska-Perun, K; Gąsińska, E; Makulska-Nowak, HE; Tatarkiewicz, J1
Dickman, JK; Herold, CA; Johnston, NF; King, EW; Radhakrishnan, R; Sluka, KA; Spurgin, ML1
Radhakrishnan, R; Rohlwing, JJ; Skyba, DA; Sluka, KA; Wright, A1
Honda, M; Kasuya, N; Ono, H; Shimizu, S; Takasu, K; Tanabe, M1
Kawamura, M; Miura, T; Namba, H; Okai, H; Okazaki, R; Yoshida, H1
Hwang, BG; Kim, JH; Kim, SK; Min, BI; Na, HS; Park, DS; Yoo, GY2
Honda, M; Ono, H; Takasu, K; Tanabe, M1
Ide, S; Ikeda, K; Ishihara, K; Minami, M; Sora, I; Uhl, GR1
Coskun, I; Dogrul, A; Uzbay, T1
Hama, A; Sagen, J1
Ono, H; Takasu, K; Takeuchi, Y; Tanabe, M1
Bruehl, S; Chung, OY; Diedrich, A; Diedrich, L; Robertson, D1
Boskovic, B; Prostran, M; Stepanović-Petrovic, R; Tomić, M; Ugresic, N; Vuckovic, S1
Bian, ZX; Leung, WM; Li, Z; Liu, L; Xu, HX; Zhang, XJ1
Devissaguet, M; Ferreira, SH; Lesieur, D; Lorenzetti, BB; Tsouderos, Y1
Aley, KO; Levine, JD1
Hiruma, Y; Matsui, Y; Matsutani, K; Tsuruoka, M1
Choi, Y; Grethel, EJ; Meyer, RA; Raja, SN; Ringkamp, M1
Kawamata, M; Kawamata, T; Namiki, A; Omote, K; Sonoda, H1

Trials

1 trial(s) available for yohimbine and Allodynia

ArticleYear
The relationship between resting blood pressure and acute pain sensitivity: effects of chronic pain and alpha-2 adrenergic blockade.
    Journal of behavioral medicine, 2008, Volume: 31, Issue:1

    Topics: Adolescent; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Blood Pressure; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Fingers; Hot Temperature; Humans; Hyperalgesia; Male; Middle Aged; Pain; Pressure; Receptors, Adrenergic, alpha-2; Yohimbine; Young Adult

2008

Other Studies

49 other study(ies) available for yohimbine and Allodynia

ArticleYear
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
    Journal of medicinal chemistry, 2008, Nov-27, Volume: 51, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship

2008
Participation of the descending noradrenergic inhibitory system in the anti-hyperalgesic effect of acetaminophen in a rat model of inflammation.
    Life sciences, 2021, Dec-01, Volume: 286

    Topics: Acetaminophen; Animals; Carrageenan; Disease Models, Animal; Hyperalgesia; Inflammation; Locus Coeruleus; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Spinal Cord; Yohimbine

2021
Effect of Immature
    Medicina (Kaunas, Lithuania), 2023, Jan-30, Volume: 59, Issue:2

    Topics: Analgesics; Animals; Dexmedetomidine; Hyperalgesia; Interleukin-6; Male; Naloxone; Pain, Postoperative; Plant Extracts; Rats; Rats, Sprague-Dawley; Rubus; Yohimbine

2023
Duloxetine and Amitriptyline Reduce Neuropathic Pain by Inhibiting Primary Sensory Input to Spinal Dorsal Horn Neurons via α1- and α2-Adrenergic Receptors.
    ACS chemical neuroscience, 2023, 04-05, Volume: 14, Issue:7

    Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Duloxetine Hydrochloride; Hyperalgesia; Neuralgia; Norepinephrine; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Spinal Cord Dorsal Horn; Yohimbine

2023
Involvement of descending pain control system regulated by orexin receptor signaling in the induction of central post-stroke pain in mice.
    European journal of pharmacology, 2020, May-05, Volume: 874

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Benzoxazoles; Brain; Brain Ischemia; Hyperalgesia; Isoquinolines; Male; Mice; Mitochondrial Proteins; Naphthyridines; Neuralgia; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Piperazines; Pyridines; Serotonin Antagonists; Signal Transduction; Urea; Yohimbine

2020
Anti-hyperalgesic effect of Lippia grata leaf essential oil complexed with β-cyclodextrin in a chronic musculoskeletal pain animal model: Complemented with a molecular docking and antioxidant screening.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 91

    Topics: Analgesics; Animals; Antioxidants; beta-Cyclodextrins; Chronic Pain; Disease Models, Animal; Hyperalgesia; Lippia; Male; Methysergide; Mice; Molecular Docking Simulation; Musculoskeletal Pain; Naloxone; Oils, Volatile; Plant Leaves; Proto-Oncogene Proteins c-fos; Spinal Cord Dorsal Horn; Yohimbine

2017
The Therapeutic Effect of Dexmedetomidine on Rat Diabetic Neuropathy Pain and the Mechanism.
    Biological & pharmaceutical bulletin, 2017, Sep-01, Volume: 40, Issue:9

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Cytokines; Dexmedetomidine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glutamic Acid; Hyperalgesia; Inflammation; Interleukin-1beta; Male; Microglia; Pain Threshold; Rats, Sprague-Dawley; Spinal Cord; Tumor Necrosis Factor-alpha; Yohimbine

2017
Noradrenaline induces peripheral antinociception by endogenous opioid release.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:4

    Topics: Analgesics; Animals; Cinnamates; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Leucine; Male; Morphine Derivatives; Naltrexone; Norepinephrine; Opioid Peptides; Pain Measurement; Prazosin; Propranolol; Rats; Yohimbine

2018
Endogenous analgesic action of the pontospinal noradrenergic system spatially restricts and temporally delays the progression of neuropathic pain following tibial nerve injury.
    Pain, 2013, Volume: 154, Issue:9

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Analysis of Variance; Animals; Disease Models, Animal; Dopamine beta-Hydroxylase; Electromyography; Functional Laterality; Hyperalgesia; Male; Neuralgia; Pain Measurement; Pain Threshold; Pons; Prazosin; Rats; Rats, Wistar; Spinal Cord; Tibial Neuropathy; Time Factors; Yohimbine

2013
The role of α₂ adrenoceptor in mediating noradrenaline action in the ventrolateral orbital cortex on allodynia following spared nerve injury.
    Experimental neurology, 2013, Volume: 248

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Bicuculline; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; GABA Antagonists; Hyperalgesia; Male; Norepinephrine; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sciatic Nerve; Sciatic Neuropathy; Yohimbine

2013
Diluted bee venom injection reduces ipsilateral mechanical allodynia in oxaliplatin-induced neuropathic mice.
    Biological & pharmaceutical bulletin, 2013, Volume: 36, Issue:11

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Bee Venoms; Hyperalgesia; Injections; Male; Mice; Mice, Inbred C57BL; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Receptors, Adrenergic, alpha-2; Yohimbine

2013
Spinal-supraspinal and intrinsic μ-opioid receptor agonist-norepinephrine reuptake inhibitor (MOR-NRI) synergy of tapentadol in diabetic heat hyperalgesia in mice.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 347, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Analgesics, Opioid; Animals; Data Interpretation, Statistical; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Hot Temperature; Hyperalgesia; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Pain Measurement; Phenols; Receptors, Opioid, mu; Spinal Cord; Tapentadol; Yohimbine

2013
Modulation of imidazoline I2 binding sites by CR4056 relieves postoperative hyperalgesia in male and female rats.
    British journal of pharmacology, 2014, Volume: 171, Issue:15

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Opioid; Animals; Benzofurans; Binding Sites; Drug Synergism; Female; Hyperalgesia; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Morphine; Naloxone; Narcotic Antagonists; Pain, Postoperative; Quinazolines; Rats, Sprague-Dawley; Yohimbine

2014
Antinociceptive effects of venlafaxine in a rat model of peripheral neuropathy: role of alpha2-adrenergic receptors.
    European journal of pharmacology, 2014, Sep-05, Volume: 738

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Behavior, Animal; Cyclohexanols; Hyperalgesia; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Venlafaxine Hydrochloride; Yohimbine

2014
Glial cell line-derived neurotrophic factor-mediated enhancement of noradrenergic descending inhibition in the locus coeruleus exerts prolonged analgesia in neuropathic pain.
    British journal of pharmacology, 2015, Volume: 172, Issue:10

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Neurons; Analgesics; Animals; Butadienes; Enzyme Inhibitors; Glial Cell Line-Derived Neurotrophic Factor; Hyperalgesia; Injections, Spinal; Locus Coeruleus; Male; MAP Kinase Signaling System; Microinjections; Neuralgia; Nitriles; Rats; Sciatic Nerve; Yohimbine

2015
Angiotensin-(1-7) through Mas receptor activation induces peripheral antinociception by interaction with adrenoreceptors.
    Peptides, 2015, Volume: 69

    Topics: Adrenergic beta-Antagonists; Analgesics; Angiotensin I; Animals; Dinoprostone; Hyperalgesia; Norepinephrine; Pain Measurement; Peptide Fragments; Prazosin; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, Adrenergic, beta; Receptors, G-Protein-Coupled; Yohimbine

2015
The inhibitory effect of locally injected dexmedetomidine on carrageenan-induced nociception in rats.
    European journal of pharmacology, 2015, Oct-05, Volume: 764

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Carrageenan; Dexmedetomidine; Hyperalgesia; Injections; Male; Nociception; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine

2015
Inhalation of Cedrus atlantica essential oil alleviates pain behavior through activation of descending pain modulation pathways in a mouse model of postoperative pain.
    Journal of ethnopharmacology, 2015, Dec-04, Volume: 175

    Topics: Administration, Inhalation; Adrenergic alpha-2 Receptor Antagonists; alpha-Methyltyrosine; Analgesics; Animals; Behavior, Animal; Cedrus; Disease Models, Animal; Dopamine Antagonists; Fenclonine; Foot; Haloperidol; Hyperalgesia; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Oils, Volatile; Pain, Postoperative; Phytotherapy; Serotonin Antagonists; Yohimbine

2015
Repetitive Acupuncture Point Treatment with Diluted Bee Venom Relieves Mechanical Allodynia and Restores Intraepidermal Nerve Fiber Loss in Oxaliplatin-Induced Neuropathic Mice.
    The journal of pain, 2016, Volume: 17, Issue:3

    Topics: Acupuncture Points; Acupuncture Therapy; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Bee Venoms; Disease Models, Animal; Epidermis; Foot; Hyperalgesia; Male; Mice, Inbred C57BL; Nerve Fibers; Organoplatinum Compounds; Oxaliplatin; Pain; Pain Threshold; Peripheral Nervous System Diseases; Random Allocation; Receptors, Adrenergic, alpha-2; Touch; Yohimbine

2016
Nitric oxide is involved in ibuprofen preemptive analgesic effect in the plantar incisional model of postsurgical pain in mice.
    Neuroscience letters, 2016, Feb-12, Volume: 614

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Arginine; Hindlimb; Hyperalgesia; Ibuprofen; Male; Mice; Nitric Oxide; Pain, Postoperative; Physical Stimulation; Receptors, Adrenergic, alpha-2; Spinal Cord; Touch; Yohimbine

2016
Sex differences in hypothalamic-mediated tonic norepinephrine release for thermal hyperalgesia in rats.
    Neuroscience, 2016, Jun-02, Volume: 324

    Topics: Adrenergic alpha-Antagonists; Animals; Cobalt; Constriction, Pathologic; Dioxanes; Disease Models, Animal; Female; Hot Temperature; Hyperalgesia; Hypothalamus; Male; Neuralgia; Nociceptive Pain; Norepinephrine; Random Allocation; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Sciatic Nerve; Sex Characteristics; Yohimbine

2016
alpha(1)-Adrenoceptors augment thermal hyperalgesia in mildly burnt skin.
    European journal of pain (London, England), 2009, Volume: 13, Issue:3

    Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Burns; Clonidine; Female; Hot Temperature; Humans; Hyperalgesia; Iontophoresis; Male; Nociceptors; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Sensory Receptor Cells; Skin; Yohimbine; Young Adult

2009
Probable involvement of alpha(2C)-adrenoceptor subtype and endogenous opioid peptides in the peripheral antinociceptive effect induced by xylazine.
    European journal of pharmacology, 2009, Apr-17, Volume: 608, Issue:1-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Idazoxan; Imidazoles; Leucine; Male; Naloxone; Opioid Peptides; Pain; Pain Measurement; Rats; Rats, Wistar; Xylazine; Yohimbine

2009
Anti-hypersensitivity effects of Shu-jing-huo-xue-tang, a Chinese herbal medicine, in CCI-neuropathic rats.
    Journal of ethnopharmacology, 2010, Sep-15, Volume: 131, Issue:2

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Behavior, Animal; Constriction; Drugs, Chinese Herbal; Hot Temperature; Hyperalgesia; Magnoliopsida; Male; Methysergide; Neuralgia; Phytotherapy; Pressure; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sciatic Neuropathy; Serotonin Antagonists; Yohimbine

2010
Chemical or surgical sympathectomy prevents mechanical hyperalgesia induced by intraplantar injection of bee venom in rats.
    Brain research, 2010, Sep-24, Volume: 1353

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Bee Venoms; Disease Models, Animal; Foot; Guanethidine; Hyperalgesia; Male; Motor Activity; Norepinephrine; Oxidopamine; Pain Threshold; Phentolamine; Prazosin; Rats; Rats, Sprague-Dawley; Reaction Time; Sympathectomy; Sympatholytics; Time Factors; Yohimbine

2010
The antinociceptive effects of estradiol on adjuvant-induced hyperalgesia in rats involve activation of adrenergic and serotonergic systems.
    Journal of anesthesia, 2011, Volume: 25, Issue:3

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Estradiol; Freund's Adjuvant; Hyperalgesia; Injections, Spinal; Male; Methysergide; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Yohimbine

2011
Chromaffin cell transplant in spinal cord reduces secondary allodynia induced by formalin in the rat. Role of opioid receptors and α₂-adrenoceptors.
    European journal of pharmacology, 2011, Oct-01, Volume: 668, Issue:1-2

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Cell Survival; Chromaffin Cells; Female; Formaldehyde; Hyperalgesia; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Spinal Cord; Yohimbine

2011
Effects of clonidine on bilateral pain behaviors and inflammatory response in rats under the state of neuropathic pain.
    Neuroscience letters, 2011, Nov-21, Volume: 505, Issue:3

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analysis of Variance; Animals; Clonidine; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Functional Laterality; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hyperalgesia; Inflammation; Macrophage-1 Antigen; Male; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sciatica; Time Factors; Yohimbine

2011
The mechanisms of antihyperalgesic effect of topiramate in a rat model of inflammatory hyperalgesia.
    Fundamental & clinical pharmacology, 2013, Volume: 27, Issue:3

    Topics: Analgesics; Animals; Bicuculline; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Fructose; Hyperalgesia; Inflammation; Male; Naloxone; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, GABA-A; Receptors, Opioid; Topiramate; Yohimbine

2013
Ankle joint mobilization affects postoperative pain through peripheral and central adenosine A1 receptors.
    Physical therapy, 2013, Volume: 93, Issue:3

    Topics: Adenosine; Analysis of Variance; Animals; Ankle Joint; Caffeine; Clonidine; Disease Models, Animal; Fenclonine; Hyperalgesia; Male; Mice; Morphine; Pain, Postoperative; Receptor, Adenosine A1; Xanthines; Yohimbine

2013
Venlafaxine and neuropathic pain.
    Pharmacology, 2013, Volume: 91, Issue:1-2

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Cyclohexanols; Diabetes Mellitus, Experimental; Hyperalgesia; Male; Naloxone; Narcotic Antagonists; Neuralgia; p-Chloroamphetamine; Pain Threshold; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Venlafaxine Hydrochloride; Yohimbine

2013
Spinal 5-HT(2) and 5-HT(3) receptors mediate low, but not high, frequency TENS-induced antihyperalgesia in rats.
    Pain, 2003, Volume: 105, Issue:1-2

    Topics: Adrenergic alpha-Antagonists; Animals; Carrageenan; Hyperalgesia; Injections, Spinal; Kaolin; Male; Methysergide; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Spinal Cord; Transcutaneous Electric Nerve Stimulation; Yohimbine

2003
Joint manipulation reduces hyperalgesia by activation of monoamine receptors but not opioid or GABA receptors in the spinal cord.
    Pain, 2003, Volume: 106, Issue:1-2

    Topics: Adrenergic alpha-Antagonists; Animals; Bicuculline; GABA Antagonists; Hyperalgesia; Joints; Male; Methysergide; Naloxone; Narcotic Antagonists; Pain; Pain Management; Physical Stimulation; Physical Therapy Modalities; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, GABA; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord; Yohimbine

2003
Role of descending noradrenergic system and spinal alpha2-adrenergic receptors in the effects of gabapentin on thermal and mechanical nociception after partial nerve injury in the mouse.
    British journal of pharmacology, 2005, Volume: 144, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Foot; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hot Temperature; Hyperalgesia; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain Measurement; Prazosin; Receptors, Adrenergic, alpha-2; Sciatic Nerve; Touch; Yohimbine

2005
Mechanisms of analgesic action of neurotropin on chronic pain in adjuvant-induced arthritic rat: roles of descending noradrenergic and serotonergic systems.
    Journal of pharmacological sciences, 2005, Volume: 97, Issue:3

    Topics: Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Arthritis, Experimental; Chronic Disease; Clonidine; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Intravenous; Injections, Spinal; Lumbosacral Region; Male; Methysergide; Pain; Pain Threshold; Polysaccharides; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin Antagonists; Time Factors; Tropanes; Yohimbine

2005
Effects of alpha1- and alpha2-adrenoreceptor antagonists on cold allodynia in a rat tail model of neuropathic pain.
    Brain research, 2005, Mar-28, Volume: 1039, Issue:1-2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Cold Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Male; Nociceptors; Pain Threshold; Prazosin; Rats; Rats, Sprague-Dawley; Spinal Nerves; Tail; Yohimbine

2005
Individual differences in the sensitivity of cold allodynia to phentolamine in neuropathic rats.
    European journal of pharmacology, 2005, Oct-31, Volume: 523, Issue:1-3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Cold Temperature; Disease Models, Animal; Hyperalgesia; Male; Nociceptors; Pain; Pain Threshold; Peripheral Nervous System Diseases; Phentolamine; Prazosin; Rats; Rats, Sprague-Dawley; Spinal Nerves; Time Factors; Yohimbine

2005
Spinal alpha(2)-adrenergic and muscarinic receptors and the NO release cascade mediate supraspinally produced effectiveness of gabapentin at decreasing mechanical hypersensitivity in mice after partial nerve injury.
    British journal of pharmacology, 2006, Volume: 148, Issue:2

    Topics: Adrenergic alpha-2 Receptor Antagonists; Amines; Analgesics; Animals; Atropine; Cholinesterases; Cyclohexanecarboxylic Acids; Enzyme Activation; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Idazoxan; Injections, Intraventricular; Male; Mice; Muscarinic Antagonists; Narcotic Antagonists; Neostigmine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Sciatic Nerve; Spinal Cord; Touch; Yohimbine

2006
Mu opioid receptor-dependent and independent components in effects of tramadol.
    Neuropharmacology, 2006, Volume: 51, Issue:3

    Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Conditioning, Psychological; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Hyperalgesia; Methysergide; Mice; Mice, Knockout; Narcotics; Pain Measurement; Reaction Time; Receptors, Opioid, mu; Reward; Serotonin Antagonists; Time Factors; Tramadol; Yohimbine

2006
The contribution of alpha-1 and alpha-2 adrenoceptors in peripheral imidazoline and adrenoceptor agonist-induced nociception.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:2

    Topics: Adrenergic alpha-Agonists; Agmatine; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoline Receptors; Male; Mice; Mice, Inbred BALB C; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine

2006
Altered antinociceptive efficacy of tramadol over time in rats with painful peripheral neuropathy.
    European journal of pharmacology, 2007, Mar-15, Volume: 559, Issue:1

    Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Constriction, Pathologic; Dose-Response Relationship, Drug; Hyperalgesia; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Time Factors; Tramadol; Yohimbine

2007
Pregabalin, S-(+)-3-isobutylgaba, activates the descending noradrenergic system to alleviate neuropathic pain in the mouse partial sciatic nerve ligation model.
    Neuropharmacology, 2007, Volume: 53, Issue:7

    Topics: Adrenergic Agents; Afferent Pathways; Analgesics; Animals; Behavior, Animal; Brain Stem; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; gamma-Aminobutyric Acid; Hyperalgesia; Locomotion; Male; Methoxyhydroxyphenylglycol; Mice; Norepinephrine; Oxidopamine; Pain Measurement; Pregabalin; Sciatic Neuropathy; Spinal Cord; Time Factors; Yohimbine

2007
Role of alpha2-adrenoceptors in the local peripheral antinociception by carbamazepine in a rat model of inflammatory mechanical hyperalgesia.
    Methods and findings in experimental and clinical pharmacology, 2007, Volume: 29, Issue:10

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Carbamazepine; Concanavalin A; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Hindlimb; Hyperalgesia; Inflammation; Injections; Male; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine

2007
The analgesic effect of paeoniflorin on neonatal maternal separation-induced visceral hyperalgesia in rats.
    The journal of pain, 2008, Volume: 9, Issue:6

    Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bridged-Ring Compounds; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Enzyme Inhibitors; Female; Glucosides; Hyperalgesia; Male; Maternal Deprivation; Monoterpenes; Naltrexone; Narcotic Antagonists; Pain Measurement; Pain Threshold; Pregnancy; Rats; Rats, Sprague-Dawley; Yohimbine

2008
S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance.
    British journal of pharmacology, 1995, Volume: 114, Issue:2

    Topics: Adrenalectomy; Analgesics; Animals; Arginine; Dipyrone; Drug Tolerance; Edema; Endorphins; Fever; Hyperalgesia; Indomethacin; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Pain Measurement; Rats; Rats, Wistar; Thiazoles; Yohimbine

1995
Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jan-15, Volume: 17, Issue:2

    Topics: Adenosine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Analgesics, Opioid; Animals; Clonidine; Dinoprostone; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hyperalgesia; Male; Models, Biological; Naloxone; Narcotic Antagonists; Oligonucleotides, Antisense; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Receptors, Purinergic P1; Second Messenger Systems; Substance Withdrawal Syndrome; Substance-Related Disorders; Xanthines; Yohimbine

1997
Effects of yohimbine on naloxone-induced antinociception in a rat model of inflammatory hyperalgesia.
    European journal of pharmacology, 1998, May-08, Volume: 348, Issue:2-3

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Carrageenan; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Yohimbine

1998
Mechanical hyperalgesia after spinal nerve ligation in rat is not reversed by intraplantar or systemic administration of adrenergic antagonists.
    Pain, 1999, Volume: 79, Issue:2-3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Hyperalgesia; Injections, Intradermal; Ligation; Male; Pain Measurement; Phentolamine; Prazosin; Rats; Rats, Sprague-Dawley; Spinal Nerves; Yohimbine

1999
Analgesic mechanisms of ketamine in the presence and absence of peripheral inflammation.
    Anesthesiology, 2000, Volume: 93, Issue:2

    Topics: Adrenergic alpha-Antagonists; Analgesia; Analgesics; Animals; Carrageenan; Drug Administration Schedule; Drug Interactions; Hot Temperature; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Injections, Spinal; Ketamine; Male; Methysergide; Microdialysis; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Yohimbine

2000