yohimbine has been researched along with Allodynia in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (8.00) | 18.2507 |
| 2000's | 18 (36.00) | 29.6817 |
| 2010's | 24 (48.00) | 24.3611 |
| 2020's | 4 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
| Fujimoto, Y; Juri, T; Mori, T; Nishikawa, K; Suehiro, K | 1 |
| Choi, GJ; Kang, H; Kwon, JW; Lee, OH | 1 |
| Chen, H; Chen, SR; Huang, Y; Pan, HL | 1 |
| Matsuura, W; Nakamoto, K; Tokuyama, S | 1 |
| Aktumsek, A; Antoniolli, AR; Araújo, AAS; Araújo-Filho, HG; Brito, RG; Coutinho, HDM; Lucchesi, A; Menezes, IRA; Menezes, PP; Quintans, JSS; Quintans-Júnior, LJ; Santos, PL; Scotti, L; Scotti, MT; Siqueira-Lima, PS; Zengin, G | 1 |
| Lin, B; Lu, Y; Zhong, J | 1 |
| Castor, MGME; Duarte, IDG; Guzzo, LS; Klein, A; Petrocchi, JA; Romero, TRL; Soares Santos, RR | 1 |
| Hickey, L; Hughes, SW; Hulse, RP; Lumb, BM; Pickering, AE | 1 |
| Barry, DM; Du, JQ; Huo, FQ; Qu, CL; Tang, JS; Xu, FY; Xu, WJ; Zhao, Y; Zhu, JX | 1 |
| Bong, DJ; Han, SD; Oh, B; Roh, DH; Yeo, JH; Yoon, SY | 1 |
| Christoph, T; De Vry, J; Schröder, W; Tallarida, RJ; Tzschentke, TM | 1 |
| Caselli, G; Ferrari, F; Lanza, M; Menghetti, I; Tremolada, D | 1 |
| Abed, A; Banafshe, HR; Hajhashemi, V; Mesdaghinia, A; Minaiyan, M | 1 |
| Kimura, M; Sakai, A; Sakamoto, A; Suzuki, H | 1 |
| Castor, MG; Duarte, ID; Romero, TR; Santos, RA | 1 |
| Higuchi, H; Honda, Y; Ishii-Maruhama, M; Maeda, S; Matsuoka, Y; Miyawaki, T; Morimatsu, H; Tomoyasu, Y; Yabuki-Kawase, A | 1 |
| Batisti, AP; Carlesso, MG; Donatello, N; dos Santos, AR; Emer, AA; Martins, DF; Mazzardo-Martins, L; Micke, GA; Piovezan, AP; Pizzolatti, MG; Venzke, D | 1 |
| Beitz, AJ; Kim, SJ; Kwon, SK; Lee, JH; Roh, DH; Yeo, JH; Yoon, SY | 1 |
| Bahr, MH; Hamza, M; Masoud, SI; Saad, SS | 1 |
| Banerjee, T; Holden, JE; Jeong, Y; Wagner, M | 1 |
| Drummond, PD | 1 |
| de Castro Perez, A; de Francischi, JN; Gama Duarte, ID; Romero, TR | 1 |
| An, K; Arita, H; Hanaoka, K; Hayashida, M; Huang, W; Shu, H; Zhang, L | 1 |
| Chen, HS; He, X; Qu, F; Wang, Y; Wen, WW | 1 |
| Hagiwara, S; Iwasaka, H; Noguchi, T; Okuda, K; Takatani, J; Takeshima, N; Uchino, T | 1 |
| Ambriz-Tututi, M; Drucker-Colín, R; Sánchez-González, V | 1 |
| Dong, R; Feng, X; Li, W; Liu, J; Wang, H; Xu, J; Yu, B; Zhang, F | 1 |
| Micov, AM; Paranos, SLj; Stepanović-Petrović, RM; Tomić, MA | 1 |
| Cidral-Filho, FJ; Martins, DF; Mazzardo-Martins, L; Santos, AR; Stramosk, J | 1 |
| Bujalska-Zadrożny, M; Cegielska-Perun, K; Gąsińska, E; Makulska-Nowak, HE; Tatarkiewicz, J | 1 |
| Dickman, JK; Herold, CA; Johnston, NF; King, EW; Radhakrishnan, R; Sluka, KA; Spurgin, ML | 1 |
| Radhakrishnan, R; Rohlwing, JJ; Skyba, DA; Sluka, KA; Wright, A | 1 |
| Honda, M; Kasuya, N; Ono, H; Shimizu, S; Takasu, K; Tanabe, M | 1 |
| Kawamura, M; Miura, T; Namba, H; Okai, H; Okazaki, R; Yoshida, H | 1 |
| Hwang, BG; Kim, JH; Kim, SK; Min, BI; Na, HS; Park, DS; Yoo, GY | 2 |
| Honda, M; Ono, H; Takasu, K; Tanabe, M | 1 |
| Ide, S; Ikeda, K; Ishihara, K; Minami, M; Sora, I; Uhl, GR | 1 |
| Coskun, I; Dogrul, A; Uzbay, T | 1 |
| Hama, A; Sagen, J | 1 |
| Ono, H; Takasu, K; Takeuchi, Y; Tanabe, M | 1 |
| Bruehl, S; Chung, OY; Diedrich, A; Diedrich, L; Robertson, D | 1 |
| Boskovic, B; Prostran, M; Stepanović-Petrovic, R; Tomić, M; Ugresic, N; Vuckovic, S | 1 |
| Bian, ZX; Leung, WM; Li, Z; Liu, L; Xu, HX; Zhang, XJ | 1 |
| Devissaguet, M; Ferreira, SH; Lesieur, D; Lorenzetti, BB; Tsouderos, Y | 1 |
| Aley, KO; Levine, JD | 1 |
| Hiruma, Y; Matsui, Y; Matsutani, K; Tsuruoka, M | 1 |
| Choi, Y; Grethel, EJ; Meyer, RA; Raja, SN; Ringkamp, M | 1 |
| Kawamata, M; Kawamata, T; Namiki, A; Omote, K; Sonoda, H | 1 |
1 trial(s) available for yohimbine and Allodynia
| Article | Year |
|---|---|
The relationship between resting blood pressure and acute pain sensitivity: effects of chronic pain and alpha-2 adrenergic blockade.
Topics: Adolescent; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Blood Pressure; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Fingers; Hot Temperature; Humans; Hyperalgesia; Male; Middle Aged; Pain; Pressure; Receptors, Adrenergic, alpha-2; Yohimbine; Young Adult | 2008 |
49 other study(ies) available for yohimbine and Allodynia
| Article | Year |
|---|---|
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
Participation of the descending noradrenergic inhibitory system in the anti-hyperalgesic effect of acetaminophen in a rat model of inflammation.
Topics: Acetaminophen; Animals; Carrageenan; Disease Models, Animal; Hyperalgesia; Inflammation; Locus Coeruleus; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Spinal Cord; Yohimbine | 2021 |
Effect of Immature
Topics: Analgesics; Animals; Dexmedetomidine; Hyperalgesia; Interleukin-6; Male; Naloxone; Pain, Postoperative; Plant Extracts; Rats; Rats, Sprague-Dawley; Rubus; Yohimbine | 2023 |
Duloxetine and Amitriptyline Reduce Neuropathic Pain by Inhibiting Primary Sensory Input to Spinal Dorsal Horn Neurons via α1- and α2-Adrenergic Receptors.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Duloxetine Hydrochloride; Hyperalgesia; Neuralgia; Norepinephrine; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Spinal Cord Dorsal Horn; Yohimbine | 2023 |
Involvement of descending pain control system regulated by orexin receptor signaling in the induction of central post-stroke pain in mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Benzoxazoles; Brain; Brain Ischemia; Hyperalgesia; Isoquinolines; Male; Mice; Mitochondrial Proteins; Naphthyridines; Neuralgia; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Piperazines; Pyridines; Serotonin Antagonists; Signal Transduction; Urea; Yohimbine | 2020 |
Anti-hyperalgesic effect of Lippia grata leaf essential oil complexed with β-cyclodextrin in a chronic musculoskeletal pain animal model: Complemented with a molecular docking and antioxidant screening.
Topics: Analgesics; Animals; Antioxidants; beta-Cyclodextrins; Chronic Pain; Disease Models, Animal; Hyperalgesia; Lippia; Male; Methysergide; Mice; Molecular Docking Simulation; Musculoskeletal Pain; Naloxone; Oils, Volatile; Plant Leaves; Proto-Oncogene Proteins c-fos; Spinal Cord Dorsal Horn; Yohimbine | 2017 |
The Therapeutic Effect of Dexmedetomidine on Rat Diabetic Neuropathy Pain and the Mechanism.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Cytokines; Dexmedetomidine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glutamic Acid; Hyperalgesia; Inflammation; Interleukin-1beta; Male; Microglia; Pain Threshold; Rats, Sprague-Dawley; Spinal Cord; Tumor Necrosis Factor-alpha; Yohimbine | 2017 |
Noradrenaline induces peripheral antinociception by endogenous opioid release.
Topics: Analgesics; Animals; Cinnamates; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Leucine; Male; Morphine Derivatives; Naltrexone; Norepinephrine; Opioid Peptides; Pain Measurement; Prazosin; Propranolol; Rats; Yohimbine | 2018 |
Endogenous analgesic action of the pontospinal noradrenergic system spatially restricts and temporally delays the progression of neuropathic pain following tibial nerve injury.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Analysis of Variance; Animals; Disease Models, Animal; Dopamine beta-Hydroxylase; Electromyography; Functional Laterality; Hyperalgesia; Male; Neuralgia; Pain Measurement; Pain Threshold; Pons; Prazosin; Rats; Rats, Wistar; Spinal Cord; Tibial Neuropathy; Time Factors; Yohimbine | 2013 |
The role of α₂ adrenoceptor in mediating noradrenaline action in the ventrolateral orbital cortex on allodynia following spared nerve injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Bicuculline; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; GABA Antagonists; Hyperalgesia; Male; Norepinephrine; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sciatic Nerve; Sciatic Neuropathy; Yohimbine | 2013 |
Diluted bee venom injection reduces ipsilateral mechanical allodynia in oxaliplatin-induced neuropathic mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Bee Venoms; Hyperalgesia; Injections; Male; Mice; Mice, Inbred C57BL; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Receptors, Adrenergic, alpha-2; Yohimbine | 2013 |
Spinal-supraspinal and intrinsic μ-opioid receptor agonist-norepinephrine reuptake inhibitor (MOR-NRI) synergy of tapentadol in diabetic heat hyperalgesia in mice.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Analgesics, Opioid; Animals; Data Interpretation, Statistical; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Hot Temperature; Hyperalgesia; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Pain Measurement; Phenols; Receptors, Opioid, mu; Spinal Cord; Tapentadol; Yohimbine | 2013 |
Modulation of imidazoline I2 binding sites by CR4056 relieves postoperative hyperalgesia in male and female rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Opioid; Animals; Benzofurans; Binding Sites; Drug Synergism; Female; Hyperalgesia; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Morphine; Naloxone; Narcotic Antagonists; Pain, Postoperative; Quinazolines; Rats, Sprague-Dawley; Yohimbine | 2014 |
Antinociceptive effects of venlafaxine in a rat model of peripheral neuropathy: role of alpha2-adrenergic receptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Behavior, Animal; Cyclohexanols; Hyperalgesia; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Venlafaxine Hydrochloride; Yohimbine | 2014 |
Glial cell line-derived neurotrophic factor-mediated enhancement of noradrenergic descending inhibition in the locus coeruleus exerts prolonged analgesia in neuropathic pain.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Neurons; Analgesics; Animals; Butadienes; Enzyme Inhibitors; Glial Cell Line-Derived Neurotrophic Factor; Hyperalgesia; Injections, Spinal; Locus Coeruleus; Male; MAP Kinase Signaling System; Microinjections; Neuralgia; Nitriles; Rats; Sciatic Nerve; Yohimbine | 2015 |
Angiotensin-(1-7) through Mas receptor activation induces peripheral antinociception by interaction with adrenoreceptors.
Topics: Adrenergic beta-Antagonists; Analgesics; Angiotensin I; Animals; Dinoprostone; Hyperalgesia; Norepinephrine; Pain Measurement; Peptide Fragments; Prazosin; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, Adrenergic, beta; Receptors, G-Protein-Coupled; Yohimbine | 2015 |
The inhibitory effect of locally injected dexmedetomidine on carrageenan-induced nociception in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Carrageenan; Dexmedetomidine; Hyperalgesia; Injections; Male; Nociception; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine | 2015 |
Inhalation of Cedrus atlantica essential oil alleviates pain behavior through activation of descending pain modulation pathways in a mouse model of postoperative pain.
Topics: Administration, Inhalation; Adrenergic alpha-2 Receptor Antagonists; alpha-Methyltyrosine; Analgesics; Animals; Behavior, Animal; Cedrus; Disease Models, Animal; Dopamine Antagonists; Fenclonine; Foot; Haloperidol; Hyperalgesia; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Oils, Volatile; Pain, Postoperative; Phytotherapy; Serotonin Antagonists; Yohimbine | 2015 |
Repetitive Acupuncture Point Treatment with Diluted Bee Venom Relieves Mechanical Allodynia and Restores Intraepidermal Nerve Fiber Loss in Oxaliplatin-Induced Neuropathic Mice.
Topics: Acupuncture Points; Acupuncture Therapy; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Bee Venoms; Disease Models, Animal; Epidermis; Foot; Hyperalgesia; Male; Mice, Inbred C57BL; Nerve Fibers; Organoplatinum Compounds; Oxaliplatin; Pain; Pain Threshold; Peripheral Nervous System Diseases; Random Allocation; Receptors, Adrenergic, alpha-2; Touch; Yohimbine | 2016 |
Nitric oxide is involved in ibuprofen preemptive analgesic effect in the plantar incisional model of postsurgical pain in mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Arginine; Hindlimb; Hyperalgesia; Ibuprofen; Male; Mice; Nitric Oxide; Pain, Postoperative; Physical Stimulation; Receptors, Adrenergic, alpha-2; Spinal Cord; Touch; Yohimbine | 2016 |
Sex differences in hypothalamic-mediated tonic norepinephrine release for thermal hyperalgesia in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Cobalt; Constriction, Pathologic; Dioxanes; Disease Models, Animal; Female; Hot Temperature; Hyperalgesia; Hypothalamus; Male; Neuralgia; Nociceptive Pain; Norepinephrine; Random Allocation; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Sciatic Nerve; Sex Characteristics; Yohimbine | 2016 |
alpha(1)-Adrenoceptors augment thermal hyperalgesia in mildly burnt skin.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Burns; Clonidine; Female; Hot Temperature; Humans; Hyperalgesia; Iontophoresis; Male; Nociceptors; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Sensory Receptor Cells; Skin; Yohimbine; Young Adult | 2009 |
Probable involvement of alpha(2C)-adrenoceptor subtype and endogenous opioid peptides in the peripheral antinociceptive effect induced by xylazine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Idazoxan; Imidazoles; Leucine; Male; Naloxone; Opioid Peptides; Pain; Pain Measurement; Rats; Rats, Wistar; Xylazine; Yohimbine | 2009 |
Anti-hypersensitivity effects of Shu-jing-huo-xue-tang, a Chinese herbal medicine, in CCI-neuropathic rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Behavior, Animal; Constriction; Drugs, Chinese Herbal; Hot Temperature; Hyperalgesia; Magnoliopsida; Male; Methysergide; Neuralgia; Phytotherapy; Pressure; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sciatic Neuropathy; Serotonin Antagonists; Yohimbine | 2010 |
Chemical or surgical sympathectomy prevents mechanical hyperalgesia induced by intraplantar injection of bee venom in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Bee Venoms; Disease Models, Animal; Foot; Guanethidine; Hyperalgesia; Male; Motor Activity; Norepinephrine; Oxidopamine; Pain Threshold; Phentolamine; Prazosin; Rats; Rats, Sprague-Dawley; Reaction Time; Sympathectomy; Sympatholytics; Time Factors; Yohimbine | 2010 |
The antinociceptive effects of estradiol on adjuvant-induced hyperalgesia in rats involve activation of adrenergic and serotonergic systems.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Estradiol; Freund's Adjuvant; Hyperalgesia; Injections, Spinal; Male; Methysergide; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Yohimbine | 2011 |
Chromaffin cell transplant in spinal cord reduces secondary allodynia induced by formalin in the rat. Role of opioid receptors and α₂-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Cell Survival; Chromaffin Cells; Female; Formaldehyde; Hyperalgesia; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Spinal Cord; Yohimbine | 2011 |
Effects of clonidine on bilateral pain behaviors and inflammatory response in rats under the state of neuropathic pain.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analysis of Variance; Animals; Clonidine; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Functional Laterality; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hyperalgesia; Inflammation; Macrophage-1 Antigen; Male; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sciatica; Time Factors; Yohimbine | 2011 |
The mechanisms of antihyperalgesic effect of topiramate in a rat model of inflammatory hyperalgesia.
Topics: Analgesics; Animals; Bicuculline; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Fructose; Hyperalgesia; Inflammation; Male; Naloxone; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, GABA-A; Receptors, Opioid; Topiramate; Yohimbine | 2013 |
Ankle joint mobilization affects postoperative pain through peripheral and central adenosine A1 receptors.
Topics: Adenosine; Analysis of Variance; Animals; Ankle Joint; Caffeine; Clonidine; Disease Models, Animal; Fenclonine; Hyperalgesia; Male; Mice; Morphine; Pain, Postoperative; Receptor, Adenosine A1; Xanthines; Yohimbine | 2013 |
Venlafaxine and neuropathic pain.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Cyclohexanols; Diabetes Mellitus, Experimental; Hyperalgesia; Male; Naloxone; Narcotic Antagonists; Neuralgia; p-Chloroamphetamine; Pain Threshold; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Venlafaxine Hydrochloride; Yohimbine | 2013 |
Spinal 5-HT(2) and 5-HT(3) receptors mediate low, but not high, frequency TENS-induced antihyperalgesia in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Carrageenan; Hyperalgesia; Injections, Spinal; Kaolin; Male; Methysergide; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Spinal Cord; Transcutaneous Electric Nerve Stimulation; Yohimbine | 2003 |
Joint manipulation reduces hyperalgesia by activation of monoamine receptors but not opioid or GABA receptors in the spinal cord.
Topics: Adrenergic alpha-Antagonists; Animals; Bicuculline; GABA Antagonists; Hyperalgesia; Joints; Male; Methysergide; Naloxone; Narcotic Antagonists; Pain; Pain Management; Physical Stimulation; Physical Therapy Modalities; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, GABA; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord; Yohimbine | 2003 |
Role of descending noradrenergic system and spinal alpha2-adrenergic receptors in the effects of gabapentin on thermal and mechanical nociception after partial nerve injury in the mouse.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Foot; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hot Temperature; Hyperalgesia; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain Measurement; Prazosin; Receptors, Adrenergic, alpha-2; Sciatic Nerve; Touch; Yohimbine | 2005 |
Mechanisms of analgesic action of neurotropin on chronic pain in adjuvant-induced arthritic rat: roles of descending noradrenergic and serotonergic systems.
Topics: Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Arthritis, Experimental; Chronic Disease; Clonidine; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Intravenous; Injections, Spinal; Lumbosacral Region; Male; Methysergide; Pain; Pain Threshold; Polysaccharides; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin Antagonists; Time Factors; Tropanes; Yohimbine | 2005 |
Effects of alpha1- and alpha2-adrenoreceptor antagonists on cold allodynia in a rat tail model of neuropathic pain.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Cold Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Male; Nociceptors; Pain Threshold; Prazosin; Rats; Rats, Sprague-Dawley; Spinal Nerves; Tail; Yohimbine | 2005 |
Individual differences in the sensitivity of cold allodynia to phentolamine in neuropathic rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Cold Temperature; Disease Models, Animal; Hyperalgesia; Male; Nociceptors; Pain; Pain Threshold; Peripheral Nervous System Diseases; Phentolamine; Prazosin; Rats; Rats, Sprague-Dawley; Spinal Nerves; Time Factors; Yohimbine | 2005 |
Spinal alpha(2)-adrenergic and muscarinic receptors and the NO release cascade mediate supraspinally produced effectiveness of gabapentin at decreasing mechanical hypersensitivity in mice after partial nerve injury.
Topics: Adrenergic alpha-2 Receptor Antagonists; Amines; Analgesics; Animals; Atropine; Cholinesterases; Cyclohexanecarboxylic Acids; Enzyme Activation; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Idazoxan; Injections, Intraventricular; Male; Mice; Muscarinic Antagonists; Narcotic Antagonists; Neostigmine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Sciatic Nerve; Spinal Cord; Touch; Yohimbine | 2006 |
Mu opioid receptor-dependent and independent components in effects of tramadol.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Conditioning, Psychological; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Hyperalgesia; Methysergide; Mice; Mice, Knockout; Narcotics; Pain Measurement; Reaction Time; Receptors, Opioid, mu; Reward; Serotonin Antagonists; Time Factors; Tramadol; Yohimbine | 2006 |
The contribution of alpha-1 and alpha-2 adrenoceptors in peripheral imidazoline and adrenoceptor agonist-induced nociception.
Topics: Adrenergic alpha-Agonists; Agmatine; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoline Receptors; Male; Mice; Mice, Inbred BALB C; Norepinephrine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine | 2006 |
Altered antinociceptive efficacy of tramadol over time in rats with painful peripheral neuropathy.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Constriction, Pathologic; Dose-Response Relationship, Drug; Hyperalgesia; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Time Factors; Tramadol; Yohimbine | 2007 |
Pregabalin, S-(+)-3-isobutylgaba, activates the descending noradrenergic system to alleviate neuropathic pain in the mouse partial sciatic nerve ligation model.
Topics: Adrenergic Agents; Afferent Pathways; Analgesics; Animals; Behavior, Animal; Brain Stem; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; gamma-Aminobutyric Acid; Hyperalgesia; Locomotion; Male; Methoxyhydroxyphenylglycol; Mice; Norepinephrine; Oxidopamine; Pain Measurement; Pregabalin; Sciatic Neuropathy; Spinal Cord; Time Factors; Yohimbine | 2007 |
Role of alpha2-adrenoceptors in the local peripheral antinociception by carbamazepine in a rat model of inflammatory mechanical hyperalgesia.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Carbamazepine; Concanavalin A; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Hindlimb; Hyperalgesia; Inflammation; Injections; Male; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine | 2007 |
The analgesic effect of paeoniflorin on neonatal maternal separation-induced visceral hyperalgesia in rats.
Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bridged-Ring Compounds; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Enzyme Inhibitors; Female; Glucosides; Hyperalgesia; Male; Maternal Deprivation; Monoterpenes; Naltrexone; Narcotic Antagonists; Pain Measurement; Pain Threshold; Pregnancy; Rats; Rats, Sprague-Dawley; Yohimbine | 2008 |
S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance.
Topics: Adrenalectomy; Analgesics; Animals; Arginine; Dipyrone; Drug Tolerance; Edema; Endorphins; Fever; Hyperalgesia; Indomethacin; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Pain Measurement; Rats; Rats, Wistar; Thiazoles; Yohimbine | 1995 |
Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal.
Topics: Adenosine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Analgesics, Opioid; Animals; Clonidine; Dinoprostone; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hyperalgesia; Male; Models, Biological; Naloxone; Narcotic Antagonists; Oligonucleotides, Antisense; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Receptors, Purinergic P1; Second Messenger Systems; Substance Withdrawal Syndrome; Substance-Related Disorders; Xanthines; Yohimbine | 1997 |
Effects of yohimbine on naloxone-induced antinociception in a rat model of inflammatory hyperalgesia.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Carrageenan; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Yohimbine | 1998 |
Mechanical hyperalgesia after spinal nerve ligation in rat is not reversed by intraplantar or systemic administration of adrenergic antagonists.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Hyperalgesia; Injections, Intradermal; Ligation; Male; Pain Measurement; Phentolamine; Prazosin; Rats; Rats, Sprague-Dawley; Spinal Nerves; Yohimbine | 1999 |
Analgesic mechanisms of ketamine in the presence and absence of peripheral inflammation.
Topics: Adrenergic alpha-Antagonists; Analgesia; Analgesics; Animals; Carrageenan; Drug Administration Schedule; Drug Interactions; Hot Temperature; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Injections, Spinal; Ketamine; Male; Methysergide; Microdialysis; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Yohimbine | 2000 |