yohimbine and Ache
yohimbine has been researched along with Ache in 106 studies
Research
Studies (106)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (23.58) | 18.7374 |
| 1990's | 21 (19.81) | 18.2507 |
| 2000's | 43 (40.57) | 29.6817 |
| 2010's | 17 (16.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Haubrich, DR; Hlasta, DJ; Luttinger, D; Perrone, MH; Silbernagel, MJ; Ward, SJ | 1 |
| Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
| Micov, A; Pecikoza, U; Stepanović-Petrović, R; Tomić, M | 1 |
| Abelson, KS; Kanui, TI; Makau, CM; Towett, PK | 1 |
| Drummond, PD; Vo, L | 2 |
| Ciciani, G; Cilibrizzi, A; Crocetti, L; Di Cesare Mannelli, L; Ghelardini, C; Giovannoni, MP; Guerrini, G; Iacovone, A; Vergelli, C | 1 |
| Beitz, AJ; Kim, SJ; Kwon, SK; Lee, JH; Roh, DH; Yeo, JH; Yoon, SY | 1 |
| Almeida, RN; Aragão Neto, Hde C; Barbosa Filho, JM; Caldas Filho, MR; Fonsêca, DV; Golzio, AM; Leite, FC; Melo, CG; Piuvezam, MR; Pordeus, LC; Salgado, PR | 1 |
| Drummond, PD; Hood, S; Vo, L | 1 |
| Abelson, KSP; Kanui, TI; Makau, CM; Towett, PK | 1 |
| Hagiwara, S; Iwasaka, H; Noguchi, T; Takeshima, N | 1 |
| Andurkar, SV; Bhalla, S; Gulati, A; Matwyshyn, G; Zhang, Z | 1 |
| Barrot, M; Doridot, S; Freund-Mercier, MJ; Hein, L; Petit-Demoulière, N; Tessier, LH; Yalcin, I | 1 |
| Holden, JE; Jeong, Y | 1 |
| de Castro Perez, A; de Francischi, JN; Gama Duarte, ID; Romero, TR | 1 |
| Ding, Z; Raffa, RB | 1 |
| Bilge, SS; Bostanci, MO; Bozkurt, A; Ciftcioglu, E; Dilek, A; Güldogus, F; Ilkaya, F; Ulger, F | 1 |
| Pettersen, VL; Raimundo, JM; Sudo, RT; Trachez, MM; Zapata-Sudo, G | 1 |
| Mokha, SS; Nag, S | 1 |
| Calasans-Maia, JA; Galdino, SL; Hernandes, MZ; Lima, MC; Pitta, IR; Sudo, RT; Zapata-Sudo, G | 1 |
| Hsu, SF; Huang, YJ; Li, YL; Sun, WZ; Wang, CC; Wen, YR; Yeh, GC | 1 |
| Dukat, M; Scheinin, M; Vainio, M; Young, S | 1 |
| Kanai, T; Maruta, T; Nemoto, T; Satoh, S; Tsuneyoshi, I; Wada, A; Yanagita, T | 1 |
| Li, JX; Winter, JC; Zhang, Y | 1 |
| Andurkar, SV; Gulati, A | 1 |
| Bruce, W; Compton, J; Fonder, H; Garrett, N | 1 |
| Ferraro, G; Gorzalczany, S; Lopez, P; Miño, J; Morucci, F | 1 |
| Abrahão, RQ; Andrade, D; Dale, CS; Franciosi, AC; Giorgi, R; Juliano, L; Juliano, MA | 1 |
| Jain, NK; Kulkarni, SK; Singh, A | 1 |
| Choi, SS; Han, EJ; Han, KJ; Kim, DH; Lee, HK; Lee, JK; Suh, HW | 1 |
| Eger, EI; Laster, MJ; Sonner, JM; Xing, Y | 1 |
| Sahebgharani, M; Vousooghi, N; Zarrindast, MR | 1 |
| Radhakrishnan, R; Rohlwing, JJ; Skyba, DA; Sluka, KA; Wright, A | 1 |
| Kawamura, M; Miura, T; Namba, H; Okai, H; Okazaki, R; Yoshida, H | 1 |
| Daniel, D; Flood, P; Rowley, TJ | 1 |
| Fukuda, Y; Hasue, F; Kuwaki, T; Shimoyama, M; Yamada, H | 1 |
| Angers, P; Dalbó, S; Jürgensen, S; Ribeiro-do-Valle, RM; Santos, AR | 1 |
| Hwang, BG; Kim, JH; Kim, SK; Min, BI; Na, HS; Park, DS; Yoo, GY | 1 |
| David, JM; David, JP; Lima-Júnior, RC; Maia, JL; Rao, VS; Santos, FA | 1 |
| Abdulla, MM; Hegab, MI | 1 |
| Baek, YH; Choi, DY; Huh, JE; Lee, JD; Park, DS | 1 |
| Hossein-Abad, AA; Sahebgharani, M; Zarrindast, MR | 1 |
| Campos, AR; David, JM; David, JP; Lima-Júnior, RC; Maia, JL; Melo, CM; Rao, VS; Santos, FA | 1 |
| Khansefid, N; Ladgevardi, MA; Sabetkasaie, M | 1 |
| Fernández-Guasti, A; Jiménez-Velázquez, G; López-Muñoz, FJ | 1 |
| Hama, A; Sagen, J | 1 |
| Ardenghi, JV; De Souza, MM; Filho, VC; Kanegusuku, M; Monache, FD; Niero, R; Yunes, RA | 1 |
| Li, CL; Li, RT; Sun, Q; Ye, J; Yue, CQ | 1 |
| Goto, F; Ito, N; Obata, H; Saito, S; Sasaki, M | 1 |
| Bruehl, S; Chung, OY; Diedrich, A; Diedrich, L; Robertson, D | 1 |
| Bruehl, S; Chont, M; Chung, OY; Diedrich, A; Diedrich, L; Robertson, D | 1 |
| Boskovic, B; Prostran, M; Stepanović-Petrovic, R; Tomić, M; Ugresic, N; Vuckovic, S | 1 |
| Angelotti, T; Mokha, SS; Nag, S; Thompson, AD | 1 |
| Freire, AC; Leonhardt, JH | 1 |
| Eisenman, LM; Goldstein, FJ; Malseed, RT; Ossipov, MH | 1 |
| Marwaha, J | 1 |
| Proudfit, HK; Sagen, J | 1 |
| Chipkin, RE; Latranyi, MB | 1 |
| Boucher, F; Dennis, SG; Gutman, S; Melzack, R | 1 |
| Capasso, A; Di Giannuario, A; Loizzo, A; Pieretti, S; Sorrentino, L | 1 |
| Hole, K; Kanui, TI; Lund, A; Mjellem-Joly, N; Tjølsen, A | 1 |
| Dawes, P; Rochford, J; Stewart, J | 1 |
| Choi, YS; Do, JC; Kim, YH; Lee, KH; Son, KH; Song, DK; Suh, HW; Woo, MH | 1 |
| Calixto, JB; Filho, VC; Santos, AR; Yunes, RA | 1 |
| Iwasaki, H; Kawamata, M; Kawamata, T; Namiki, A; Omote, K | 1 |
| Kawamata, M; Kawamata, T; Namiki, A; Omote, K | 1 |
| Kanda, T; Kemmotsu, O; Kida, A; Ohta, Y | 1 |
| Lutz, EA; Shannon, HE | 2 |
| Muir, WW; Skarda, RT | 1 |
| Burton, DD; Camilleri, M; Fett, SL; Kost, L; Malcolm, A; Zinsmeister, AR | 1 |
| Buéno, L; Fioramonti, J; Maggi, C; Toulouse, M | 1 |
| Alguacil, LF; Morales, L; Perez-Garcia, C | 1 |
| Uzbay, IT; Yeşilyurt, O | 1 |
| Sahebgharani, M; Zarrindast, MR | 1 |
| Fu, TC; Guo, L; Liu, HJ; Peng, YI | 1 |
| Besson, JM; Guilbaud, G; Kayser, V | 2 |
| Proudfit, HK; Yeomans, DC | 1 |
| Bojö, L; Cassuto, J; Nellgård, P | 1 |
| Dawes, P; Rochford, J | 1 |
| Reid, A; Sawynok, J | 1 |
| Foo, H; Westbrook, RF | 1 |
| Danzebrink, RM; Gebhart, GF | 1 |
| Miller, JF; Proudfit, HK | 1 |
| Christensen, MK; Smith, DF | 1 |
| Collins, JG; Kitahata, LM; Murata, K; Nakagawa, I; Omote, K | 1 |
| Nance, PW; Sawynok, J | 1 |
| Barber, A; Harting, J; Wolf, HP | 1 |
| Collins, JG; Kitahata, LM; Kumeta, Y; Murata, K; Nakagawa, I | 1 |
| Tang, R; Tseng, LL | 1 |
| Sotgiu, ML | 1 |
| Kobatake, M; Nakamura, A; Shiomi, H; Sugao, T; Yamaue, K | 1 |
| Butkhuzi, SM; Kolchin, VV; Moroz, BT; Sakvarelidze, ZA; Zaĭtsev, AA | 1 |
| Bansinath, M; Puig, MM; Ramabadran, K; Turndorf, H | 1 |
| Jørum, E | 1 |
| Simson, PE; Weiss, JM | 1 |
| Gebhart, GF; Janss, AJ | 1 |
| Barbaro, NM; Fields, HL; Hammond, DL | 1 |
| Davies, J; Quinlan, JE | 1 |
| Rae, GA; Souza, RL; Takahashi, RN | 1 |
| Curtis, AL; Marwah, J | 1 |
| Gebhart, GF; Solomon, RE | 1 |
| Haigler, HJ; O'Neill, TP | 1 |
| Adithan, C; Bapna, JS; Raveendran, R; Sivagnanam, G; Thakur, LC | 1 |
Trials
5 trial(s) available for yohimbine and Ache
| Article | Year |
|---|---|
Involvement of α2-adrenoceptors in inhibitory and facilitatory pain modulation processes.
Topics: Adolescent; Adrenergic alpha-2 Receptor Antagonists; Adult; Blinking; Cold Temperature; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Female; Functional Laterality; Hot Temperature; Humans; Male; Middle Aged; Nociception; Pain; Physical Stimulation; Receptors, Adrenergic, alpha-2; Yohimbine; Young Adult | 2016 |
Involvement of Opioid Receptors and α
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adult; Blood Pressure; Central Nervous System Sensitization; Clonidine; Cross-Over Studies; Double-Blind Method; Drug Administration Routes; Electric Stimulation; Female; Healthy Volunteers; Heart Rate; Humans; Male; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Psychophysics; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Yohimbine; Young Adult | 2016 |
The relationship between resting blood pressure and acute pain sensitivity: effects of chronic pain and alpha-2 adrenergic blockade.
Topics: Adolescent; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Blood Pressure; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Fingers; Hot Temperature; Humans; Hyperalgesia; Male; Middle Aged; Pain; Pressure; Receptors, Adrenergic, alpha-2; Yohimbine; Young Adult | 2008 |
Baroreflex sensitivity associated hypoalgesia in healthy states is altered by chronic pain.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Baroreflex; Chronic Disease; Double-Blind Method; Female; Humans; Male; Pain; Pain Threshold; Receptors, Adrenergic, alpha-2; Yohimbine | 2008 |
Effects of intravenously administered yohimbine on antinociceptive, cardiorespiratory, and postural changes induced by epidural administration of detomidine hydrochloride solution to healthy mares.
Topics: Adrenergic alpha-Antagonists; Analgesia; Analgesics; Animals; Carbon Dioxide; Cardiac Output; Cross-Over Studies; Diuresis; Electric Stimulation; Female; Heart Rate; Hemodynamics; Horses; Imidazoles; Injections, Epidural; Injections, Intravenous; Oxygen; Pain; Posture; Respiratory Mechanics; Sweating; Yohimbine | 1999 |
Other Studies
101 other study(ies) available for yohimbine and Ache
| Article | Year |
|---|---|
Alpha 2-adrenergic agonists/antagonists: the synthesis and structure-activity relationships of a series of indolin-2-yl and tetrahydroquinolin-2-yl imidazolines.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Imidazoles; Indoles; Male; Mice; Nociceptors; Pain; Prazosin; Quinolines; Rats; Structure-Activity Relationship; Vas Deferens | 1987 |
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
Eslicarbazepine acetate reduces trigeminal nociception: Possible role of adrenergic, cholinergic and opioid receptors.
Topics: Adrenergic Antagonists; Analgesics; Animals; Atropine; Cholinergic Antagonists; Dibenzazepines; Formaldehyde; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Opioid; Trigeminal Neuralgia; Yohimbine | 2018 |
Intrathecal administration of clonidine or yohimbine decreases the nociceptive behavior caused by formalin injection in the marsh terrapin (Pelomedusa subrufa).
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; Injections, Spinal; Methysergide; Pain; Pain Measurement; Random Allocation; Serotonin Antagonists; Turtles; Yohimbine | 2014 |
Synthesis of five and six-membered heterocycles bearing an arylpiperazinylalkyl side chain as orally active antinociceptive agents.
Topics: Acetic Acid; Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Heterocyclic Compounds; Mice; Pain; Pyridazines; Yohimbine | 2015 |
Repetitive Acupuncture Point Treatment with Diluted Bee Venom Relieves Mechanical Allodynia and Restores Intraepidermal Nerve Fiber Loss in Oxaliplatin-Induced Neuropathic Mice.
Topics: Acupuncture Points; Acupuncture Therapy; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Bee Venoms; Disease Models, Animal; Epidermis; Foot; Hyperalgesia; Male; Mice, Inbred C57BL; Nerve Fibers; Organoplatinum Compounds; Oxaliplatin; Pain; Pain Threshold; Peripheral Nervous System Diseases; Random Allocation; Receptors, Adrenergic, alpha-2; Touch; Yohimbine | 2016 |
Ortho-eugenol exhibits anti-nociceptive and anti-inflammatory activities.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Cell Movement; Eugenol; Hot Temperature; Interleukin-1beta; Leukocytes; Male; Mice; Motor Activity; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pain; Tumor Necrosis Factor-alpha; Yohimbine | 2016 |
Modulation of formalin-induced pain-related behaviour by clonidine and yohimbine in the Speke's hinged tortoise (Kiniskys spekii).
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Formaldehyde; Pain; Turtles; Yohimbine | 2017 |
Effect of combined opioid receptor and α
Topics: Adolescent; Adrenergic alpha-2 Receptor Antagonists; Adult; Analgesics, Opioid; Anxiety; Blinking; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Pain; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Reflex, Startle; Yohimbine; Young Adult | 2017 |
Mechanisms of analgesic action of pulsed radiofrequency on adjuvant-induced pain in the rat: roles of descending adrenergic and serotonergic systems.
Topics: Adrenergic alpha-Antagonists; Analgesia; Animals; Brain Stem; Catecholamines; Catheter Ablation; Disease Models, Animal; Efferent Pathways; Freund's Adjuvant; Inflammation; Male; Neural Inhibition; Nociceptors; Pain; Pain Management; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Serotonin; Serotonin Antagonists; Treatment Outcome; Tropanes; Yohimbine | 2009 |
Determination of adrenergic and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by clonidine and BMS182874.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Area Under Curve; Clonidine; Dansyl Compounds; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine | 2009 |
Beta2-adrenoceptors are essential for desipramine, venlafaxine or reboxetine action in neuropathic pain.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amines; Animals; Anticonvulsants; Antidepressive Agents; Cyclohexanecarboxylic Acids; Cyclohexanols; Desipramine; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Mice, Transgenic; Morpholines; Pain; Pain Threshold; Propanolamines; Reboxetine; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Sciatic Nerve; Venlafaxine Hydrochloride; Yohimbine | 2009 |
Lateral hypothalamic-induced alpha-adrenoceptor modulation occurs in a model of inflammatory pain in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Female; Hypothalamic Area, Lateral; Inflammation; Isothiocyanates; Nociceptors; Nursing Research; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Adrenergic, alpha; Tarsus, Animal; Yohimbine | 2009 |
Probable involvement of alpha(2C)-adrenoceptor subtype and endogenous opioid peptides in the peripheral antinociceptive effect induced by xylazine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Idazoxan; Imidazoles; Leucine; Male; Naloxone; Opioid Peptides; Pain; Pain Measurement; Rats; Rats, Wistar; Xylazine; Yohimbine | 2009 |
Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Aminoquinolines; Analgesics, Opioid; Anesthetics, Local; Animals; Benzamides; Brain; Buprenorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fentanyl; GTP-Binding Proteins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Okadaic Acid; Oligonucleotides, Antisense; Opioid Peptides; Pain; Pain Measurement; Pain Threshold; Pertussis Toxin; Phosphoprotein Phosphatases; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Receptors, Opioid; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Yohimbine | 2009 |
The antinociceptive effects of intravenous dexmedetomidine in colorectal distension-induced visceral pain in rats: the role of opioid receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Catheterization; Clonidine; Colon; Data Interpretation, Statistical; Dexmedetomidine; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Physical Stimulation; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Rectum; Yohimbine | 2009 |
The synergistic interaction between morphine and maprotiline after intrathecal injection in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Injections, Spinal; Male; Maprotiline; Morphine; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Selective Serotonin Reuptake Inhibitors; Time Factors; Yohimbine | 2009 |
Testosterone is essential for alpha(2)-adrenoceptor-induced antinociception in the trigeminal region of the male rat.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Catheterization; Clonidine; Estradiol; Estrogens; Hormone Replacement Therapy; Hot Temperature; Male; N-Methylaspartate; Orchiectomy; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Testosterone; Testosterone Propionate; Time Factors; Trigeminal Nuclei; Yohimbine | 2009 |
Interaction of morphine with a new alpha2-adrenoceptor agonist in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Synergism; Imidazoles; Imidazolidines; Isoindoles; Male; Mice; Models, Molecular; Morphine; Pain; Random Allocation; Receptors, Adrenergic, alpha-2; Yohimbine | 2010 |
DNIC-mediated analgesia produced by a supramaximal electrical or a high-dose formalin conditioning stimulus: roles of opioid and alpha2-adrenergic receptors.
Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Analgesia; Analysis of Variance; Animals; Area Under Curve; Conditioning, Psychological; Electric Stimulation; Formaldehyde; Immunohistochemistry; Male; Naloxone; Narcotic Antagonists; Neural Inhibition; Pain; Rats; Rats, Sprague-Dawley; Yohimbine | 2010 |
Antinociceptive synergism of MD-354 and clonidine. Part II. The alpha-adrenoceptor component.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Behavior, Animal; Clonidine; Drug Synergism; Guanidines; Imidazoles; Injections, Subcutaneous; Isoindoles; Male; Mice; Mice, Inbred ICR; Motor Activity; Pain; Pain Measurement; Receptors, Adrenergic, alpha; Tail; Yohimbine | 2010 |
Dexmedetomidine and clonidine inhibit the function of Na(v)1.7 independent of α(2)-adrenoceptor in adrenal chromaffin cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding Sites; Cattle; Cells, Cultured; Chromaffin Cells; Clonidine; Cyclopentanes; Dexmedetomidine; Imidazoles; Lidocaine; Organophosphorus Compounds; Ouabain; Pain; Receptors, Adrenergic, alpha-2; Scorpion Venoms; Sodium; Sodium Channels; Tetrodotoxin; Veratridine; Yohimbine | 2011 |
Morphine-induced antinociception in the rat: supra-additive interactions with imidazoline I₂ receptor ligands.
Topics: Adrenergic alpha-2 Receptor Antagonists; Agmatine; Analgesics; Analgesics, Opioid; Animals; Benzofurans; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoles; Imidazoline Receptors; Ligands; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Yohimbine | 2011 |
Assessment of the analgesic effect of centhaquin in mouse tail flick and hot-plate tests.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Opioid; Animals; Antihypertensive Agents; Body Temperature; Drug Interactions; Endothelin A Receptor Antagonists; Hot Temperature; Idazoxan; Imidazoline Receptors; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Pain; Piperazines; Receptor, Endothelin A; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Yohimbine | 2011 |
Investigation of modulation of the alpha-2 receptor in tetrahydropalmatine (THP) analgesia in male Sprague-Dawley rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesia; Analgesics; Analysis of Variance; Animals; Berberine Alkaloids; Corydalis; Dexmedetomidine; Herb-Drug Interactions; Hot Temperature; Hypnotics and Sedatives; Male; Pain; Pain Threshold; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine | 2009 |
Antinociceptive activity of aqueous extract and isolated compounds of Lithrea molleoides.
Topics: Acetic Acid; Adrenergic alpha-2 Receptor Antagonists; Anacardiaceae; Analgesics; Animals; Behavior, Animal; Dopamine Antagonists; Drug Administration Routes; Female; Formaldehyde; Haloperidol; Hot Temperature; Mice; Mice, Inbred Strains; Pain; Phytotherapy; Plant Extracts; Shikimic Acid; South America; Vanillic Acid; Yohimbine | 2012 |
Oligopeptidases B from Trypanossoma cruzi and Trypanossoma brucei inhibit inflammatory pain in mice by targeting serotoninergic receptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Male; Methysergide; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Receptors, Serotonin; Serine Endopeptidases; Serotonin Antagonists; Trypanosoma brucei brucei; Trypanosoma cruzi; Yohimbine | 2013 |
Modulation of NSAID-induced antinociceptive and anti-inflammatory effects by alpha2-adrenoceptor agonists with gastroprotective effects.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Drug Synergism; Drug Therapy, Combination; Meloxicam; Mice; Naproxen; Pain; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Stomach Ulcer; Sulfonamides; Thiazines; Thiazoles; Yohimbine | 2002 |
Antinociceptive mechanisms of orally administered decursinol in the mouse.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Analgesics; Animals; Benzopyrans; Butyrates; Cyproheptadine; Dose-Response Relationship, Drug; Glutamic Acid; Histamine H2 Antagonists; Interferon-gamma; Interleukin-1; Male; Methysergide; Mice; Mice, Inbred ICR; Models, Chemical; Naloxone; Narcotic Antagonists; Pain; Piperidines; Protein Kinase C; Ranitidine; Receptors, Adrenergic; Receptors, Histamine; Receptors, Purinergic P1; Receptors, Serotonin; Serotonin Antagonists; Substance P; Theobromine; Tumor Necrosis Factor-alpha; Xanthines; Yohimbine | 2003 |
Alpha-2 adrenoreceptors probably do not mediate the immobility produced by inhaled anesthetics.
Topics: Adrenergic alpha-Antagonists; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Imidazoles; Isoflurane; Male; Movement; Pain; Physical Stimulation; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Yohimbine | 2003 |
Imipramine-induced antinociception in the formalin test. Receptor mechanisms involved and effect of swim stress.
Topics: Animals; Dose-Response Relationship, Drug; Imipramine; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Naloxone; Nociceptors; Pain; Pain Measurement; Prazosin; Stress, Physiological; Swimming; Yohimbine | 2003 |
Joint manipulation reduces hyperalgesia by activation of monoamine receptors but not opioid or GABA receptors in the spinal cord.
Topics: Adrenergic alpha-Antagonists; Animals; Bicuculline; GABA Antagonists; Hyperalgesia; Joints; Male; Methysergide; Naloxone; Narcotic Antagonists; Pain; Pain Management; Physical Stimulation; Physical Therapy Modalities; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, GABA; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord; Yohimbine | 2003 |
Mechanisms of analgesic action of neurotropin on chronic pain in adjuvant-induced arthritic rat: roles of descending noradrenergic and serotonergic systems.
Topics: Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Arthritis, Experimental; Chronic Disease; Clonidine; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Intravenous; Injections, Spinal; Lumbosacral Region; Male; Methysergide; Pain; Pain Threshold; Polysaccharides; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin Antagonists; Time Factors; Tropanes; Yohimbine | 2005 |
The role of adrenergic and cholinergic transmission in volatile anesthetic-induced pain enhancement.
Topics: Adrenergic alpha-Antagonists; Algorithms; Anesthetics, Inhalation; Animals; Benzylamines; Dopamine; Female; Injections, Intraventricular; Injections, Spinal; Isoflurane; Mice; Norepinephrine; Pain; Pain Measurement; Parasympathetic Nervous System; Receptors, Nicotinic; Serotonin; Spinal Cord; Sympathetic Nervous System; Synaptic Transmission; Yohimbine | 2005 |
Inhibitory actions of endothelin-1 on pain processing.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Neural Inhibition; Neural Pathways; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptides, Cyclic; Piperidines; Prazosin; Reaction Time; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Adrenergic, alpha-1; Yohimbine | 2004 |
Involvement of 5-HT2 receptors in the antinociceptive effect of Uncaria tomentosa.
Topics: Acetic Acid; Analgesics; Animals; Arginine; Atropine; Behavior, Animal; Capsaicin; Cat's Claw; Dose-Response Relationship, Drug; Formaldehyde; Ketanserin; Male; Mice; Motor Activity; Naltrexone; Pain; Pain Measurement; Phytotherapy; Plant Preparations; Prazosin; Receptors, Serotonin, 5-HT2; Reserpine; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Yohimbine | 2005 |
Individual differences in the sensitivity of cold allodynia to phentolamine in neuropathic rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Cold Temperature; Disease Models, Animal; Hyperalgesia; Male; Nociceptors; Pain; Pain Threshold; Peripheral Nervous System Diseases; Phentolamine; Prazosin; Rats; Rats, Sprague-Dawley; Spinal Nerves; Time Factors; Yohimbine | 2005 |
Oleanolic Acid, a pentacyclic triterpene attenuates the mustard oil-induced colonic nociception in mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Colonic Diseases; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Mustard Plant; Oleanolic Acid; Pain; Plant Oils; Ruthenium Red; TRPV Cation Channels; Yohimbine | 2006 |
4-Chloro-2,2-disubstituted chromen-3-carboxaldehyde: synthesis of some fused polycyclic heterocycles as anti-inflammatory, analgesic, anticonvulsant, and antiparkinsonian agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Antiparkinson Agents; Benzopyrans; Carrageenan; Dinoprostone; Edema; Heterocyclic Compounds; Male; Mice; Oxotremorine; Pain; Parkinsonian Disorders; Rats; Rats, Wistar; Seizures; Time Factors; Yohimbine | 2006 |
Antinociceptive effect and the mechanism of bee venom acupuncture (Apipuncture) on inflammatory pain in the rat model of collagen-induced arthritis: Mediation by alpha2-Adrenoceptors.
Topics: Acupuncture Points; Adrenergic alpha-Antagonists; Animals; Arthritis, Experimental; Bee Venoms; Behavior, Animal; Collagen; Disease Models, Animal; Drug Administration Routes; Drug Interactions; Male; Naloxone; Narcotic Antagonists; Pain; Pain Management; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Adrenergic, alpha-2; Statistics, Nonparametric; Yohimbine | 2006 |
On the mechanism of carbamazepine-induced antinociception in the formalin test.
Topics: Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Formaldehyde; GABA Antagonists; Male; Mice; Organophosphorus Compounds; Pain; Pain Measurement; Prazosin; Yohimbine | 2006 |
Oleanolic acid, a pentacyclic triterpene attenuates capsaicin-induced nociception in mice: possible mechanisms.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Capsaicin; Coloring Agents; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; KATP Channels; Lamiaceae; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Oleanolic Acid; Pain; Pain Measurement; Postural Balance; Potassium Channels, Inwardly Rectifying; Ruthenium Red; Yohimbine | 2006 |
Possible role of NMDA receptors in antinociception induced by rilmenidine in mice in the formalin test.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Benzofurans; Binding Sites; Binding, Competitive; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Imidazoles; Imidazoline Receptors; Male; Mice; Nervous System; Neurons, Afferent; Nociceptors; Oxazoles; Pain; Pain Measurement; Receptors, Drug; Receptors, N-Methyl-D-Aspartate; Rilmenidine; Yohimbine | 2007 |
Influence of pharmacologically-induced experimental anxiety on nociception and antinociception in rats.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Aspirin; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Pain; Rats; Rats, Wistar; Time Factors; Yohimbine | 2006 |
Altered antinociceptive efficacy of tramadol over time in rats with painful peripheral neuropathy.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Constriction, Pathologic; Dose-Response Relationship, Drug; Hyperalgesia; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Time Factors; Tramadol; Yohimbine | 2007 |
Analysis of the mechanism of antinociceptive action of niga-ichigoside F1 obtained from Rubus imperialis (Rosaceae).
Topics: Analgesics; Animals; Apomorphine; Atropine; Capsaicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glutamic Acid; Haloperidol; Injections, Intraperitoneal; Male; Mice; Molecular Structure; Morphine; Naloxone; Nitroarginine; Pain; Pain Measurement; Plant Extracts; Rosaceae; Saponins; Yohimbine | 2006 |
Antinociceptive effects of the novel spirocyclopiperazinium salt compound LXM-10 in mice.
Topics: Analgesics; Animals; Atropine; Atropine Derivatives; Body Temperature; Drug Evaluation, Preclinical; Female; Hexamethonium; Male; Mecamylamine; Mice; Mice, Inbred ICR; Motor Activity; Naloxone; Pain; Pain Measurement; Piperazines; Psychomotor Performance; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Receptors, Nicotinic; Receptors, Opioid; Yohimbine | 2007 |
Possible involvement of spinal noradrenergic mechanisms in the antiallodynic effect of intrathecally administered 5-HT2C receptor agonists in the rats with peripheral nerve injury.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Atropine; Injections, Spinal; Ligation; Male; Muscarinic Antagonists; Norepinephrine; Pain; Peripheral Nervous System Diseases; Physical Stimulation; Piperazines; Pyrazines; Rats; Rats, Wistar; Serotonin 5-HT2 Receptor Agonists; Spinal Cord; Spinal Nerves; Touch; Yohimbine | 2007 |
Role of alpha2-adrenoceptors in the local peripheral antinociception by carbamazepine in a rat model of inflammatory mechanical hyperalgesia.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Carbamazepine; Concanavalin A; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Hindlimb; Hyperalgesia; Inflammation; Injections; Male; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine | 2007 |
Sex-specific modulation of spinal nociception by alpha2-adrenoceptors: differential regulation by estrogen and testosterone.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Area Under Curve; Behavior, Animal; Castration; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Estrogens; Female; Male; N-Methylaspartate; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sex Characteristics; Testosterone; Time Factors; Yohimbine | 2008 |
Further studies on the xylazine-yohimbine interaction.
Topics: Abdomen; Acetates; Acetic Acid; Animals; Kinetics; Male; Mice; Muscle Cramp; Pain; Receptors, Adrenergic, alpha; Thiazines; Xylazine; Yohimbine | 1984 |
Effect of alpha 2 adrenergic agents upon central etorphine antinociception in the cat.
Topics: Adrenergic alpha-Agonists; Animals; Cats; Clonidine; Drug Interactions; Etorphine; Guanfacine; Guanidines; Kinetics; Male; Morphinans; Nociceptors; Pain; Phenylacetates; Yohimbine | 1984 |
Supersensitivity of analgesic responses to alpha 2-adrenergic agonists in genetically hypertensive rats.
Topics: Animals; Clonidine; Hypertension; Male; Naphazoline; Pain; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Effect of intrathecally administered noradrenergic antagonists on nociception in the rat.
Topics: Animals; Brain Mapping; Brain Stem; Dioxanes; Efferent Pathways; Injections, Spinal; Male; Norepinephrine; Pain; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Spinal Cord; Yohimbine | 1984 |
Subplantar yeast injection induces a non-naloxone reversible antinociception in spontaneously hypertensive rats.
Topics: Animals; Endorphins; Hypertension; Male; Naloxone; Norepinephrine; Pain; Rats; Rats, Inbred Strains; Reaction Time; Yeast, Dried; Yohimbine | 1984 |
Pain modulation by adrenergic agents and morphine as measured by three pain tests.
Topics: Animals; Drug Interactions; Male; Methods; Morphine; Naloxone; Pain; Rats; Reaction Time; Sympathomimetics; Time Factors; Yohimbine | 1980 |
Effects induced by cysteamine on chemically-induced nociception in mice.
Topics: Amino Acid Sequence; Animals; Cysteamine; Drug Interactions; Locomotion; Male; Mice; Molecular Sequence Data; Naloxone; Organophosphorus Compounds; Pain; Somatostatin; Yohimbine | 1994 |
Antinociceptive effects of intrathecal administration of alpha-adrenoceptor antagonists and clonidine in the formalin test in the mouse.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Body Temperature; Clonidine; Formaldehyde; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain; Pain Measurement; Prazosin; Yohimbine | 1993 |
Naloxone potentiation of novelty-induced hypoalgesia: characterization of the alpha-noradrenergic receptor subtype.
Topics: Animals; Clonidine; Drug Synergism; Habituation, Psychophysiologic; Male; Naloxone; Pain; Phentolamine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1993 |
Antinociceptive effect of smilaxin B administered intracerebroventricularly in the mouse.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Cerebral Ventricles; Dizocilpine Maleate; Glycosides; Injections, Intraventricular; Injections, Spinal; Male; Methysergide; Mice; Mice, Inbred ICR; Muscimol; Naloxone; Pain; Sincalide; Spinal Cord; Spirostans; Yohimbine | 1996 |
Analysis of the mechanisms underlying the antinociceptive effect of the extracts of plants from the genus Phyllanthus.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Arginine; Capsaicin; Clonidine; Male; Mice; Nitroarginine; Pain; Phenylephrine; Plant Extracts; Prazosin; Yohimbine | 1995 |
Antinociceptive interaction of intrathecal alpha2-adrenergic agonists, tizanidine and clonidine, with lidocaine in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Animals; Blood Pressure; Clonidine; Drug Interactions; Heart Rate; Injections, Spinal; Lidocaine; Male; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Yohimbine | 1997 |
Formalin-induced nociception activates a monoaminergic descending inhibitory system.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Biogenic Monoamines; Formaldehyde; Male; Methysergide; Neural Inhibition; Pain; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Yohimbine | 1998 |
The effect of alpha2-adrenergic drugs on the activity of neurons in the rat nucleus raphe magnus in vitro.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain Stem; Clonidine; Dose-Response Relationship, Drug; Neural Inhibition; Neural Pathways; Neurons; Nociceptors; Pain; Raphe Nuclei; Rats; Rats, Wistar; Synaptic Transmission; Yohimbine | 1999 |
Effects of the I(1) imidazoline/alpha(2)-adrenergic receptor agonist moxonidine in comparison with clonidine in the formalin test in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Benzofurans; Clonidine; Dose-Response Relationship, Drug; Formaldehyde; Imidazoles; Imidazoline Receptors; Injections, Subcutaneous; Male; Pain; Pain Measurement; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Drug; Time Factors; Yohimbine | 2000 |
Yohimbine produces antinociception in the formalin test in rats: involvement of serotonin(1A) receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Ergolines; Formaldehyde; Male; Nociceptors; Oxadiazoles; Pain; Pain Measurement; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors; Yohimbine | 2000 |
Towards identifying optimal doses for alpha-2 adrenergic modulation of colonic and rectal motor and sensory function.
Topics: Adrenergic alpha-Agonists; Adult; Autonomic Nervous System; Clonidine; Colon; Colonic Diseases, Functional; Female; Gases; Gastrointestinal Motility; Humans; Male; Pain; Perception; Receptors, Adrenergic, alpha-2; Rectum; Yohimbine | 2000 |
Role of NK2 receptors in gastric barosensitivity and in experimental ileus in rats.
Topics: Adrenergic alpha-Antagonists; Air Pressure; Animals; Behavior, Animal; Electromyography; Injections, Intramuscular; Injections, Intravenous; Intestinal Obstruction; Jejunum; Male; Pain; Peptides, Cyclic; Rats; Rats, Wistar; Receptors, Neurokinin-2; Stomach; Yohimbine | 2001 |
Effects of yohimbine on the antinociceptive and place conditioning effects of opioid agonists in rodents.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Conditioning, Psychological; Drug Synergism; Hot Temperature; Male; Mice; Morphine; Motor Activity; Pain; Pain Measurement; Piperazines; Rats; Rats, Sprague-Dawley; Reaction Time; Tail; Yohimbine | 2001 |
Agmatine potentiates the analgesic effect of morphine by an alpha(2)-adrenoceptor-mediated mechanism in mice.
Topics: Adrenergic alpha-Antagonists; Agmatine; Analgesics, Opioid; Animals; Central Nervous System; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Male; Mice; Morphine; Nociceptors; Pain; Pain Measurement; Rats; Receptors, Adrenergic, alpha-2; Yohimbine | 2001 |
Effect of alpha-adrenoceptor agonists and antagonists on imipramine-induced antinociception in the rat formalin test.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Clonidine; Dose-Response Relationship, Drug; Formaldehyde; Imipramine; Injections, Intraventricular; Male; Nociceptors; Pain; Pain Measurement; Prazosin; Rats; Rats, Wistar; Yohimbine | 2002 |
Mechanisms of adrenaline-induced antinociception in mice.
Topics: Analgesics; Animals; Epinephrine; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naloxone; Pain; Prazosin; Propranolol; Sensory Thresholds; Yohimbine | 1992 |
Evidence for a noradrenergic component in the antinociceptive effect of the analgesic agent tramadol in an animal model of clinical pain, the arthritic rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arthritis; Dioxanes; Drug Interactions; Idazoxan; Injections, Intravenous; Norepinephrine; Pain; Pain Measurement; Rats; Receptors, Opioid; Tramadol; Yohimbine | 1992 |
Potent antinociceptive effects of clonidine systemically administered in an experimental model of clinical pain, the arthritic rat.
Topics: Adrenergic beta-Antagonists; Analgesics; Analysis of Variance; Animals; Arthritis, Experimental; Clonidine; Dioxanes; Idazoxan; Injections, Intravenous; Male; Pain; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Vocalization, Animal; Yohimbine | 1992 |
Antinociception induced by microinjection of substance P into the A7 catecholamine cell group in the rat.
Topics: Afferent Pathways; Analgesics; Animals; Blood Pressure; Catecholamines; Dioxanes; Female; Hot Temperature; Idazoxan; Injections, Spinal; Microinjections; Models, Neurological; Neurons; Norepinephrine; Pain; Pons; Rats; Rats, Inbred Strains; Reflex; Serotonin; Skin Temperature; Stereotaxic Techniques; Substance P; Tyrosine 3-Monooxygenase; Yohimbine | 1992 |
Pain-induced inhibition of gastric motility is mediated by adrenergic and vagal non-adrenergic reflexes in the rat.
Topics: Anesthesia; Animals; Autonomic Nervous System; Gastrointestinal Motility; Male; Muscle Relaxation; Neural Pathways; Pain; Prazosin; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vagotomy; Vagus Nerve; Yohimbine | 1992 |
Clonidine and yohimbine modulate the effects of naloxone on novelty-induced hypoalgesia.
Topics: Animals; Clonidine; Environment; Male; Naloxone; Pain; Rats; Rats, Inbred Strains; Reaction Time; Yohimbine | 1992 |
Noradrenergic and purinergic involvement in spinal antinociception by 5-hydroxytryptamine and 2-methyl-5-hydroxytryptamine.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Oxidopamine; Pain; Phentolamine; Prazosin; Purinergic Antagonists; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Purinergic; Serotonin; Spinal Cord; Theophylline; Yohimbine | 1991 |
Naloxone-induced hypoalgesia: effects of noradrenergic antagonists and agonist.
Topics: Animals; Clonidine; Hot Temperature; Male; Naloxone; Norepinephrine; Pain; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Sensory Thresholds; Yohimbine | 1991 |
Antinociceptive effects of intrathecal adrenoceptor agonists in a rat model of visceral nociception.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxanes; Idazoxan; Male; Pain; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1990 |
Antagonism of stimulation-produced antinociception from ventrolateral pontine sites by intrathecal administration of alpha-adrenergic antagonists and naloxone.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dopamine beta-Hydroxylase; Electric Stimulation; Female; Injections, Spinal; Methysergide; Microinjections; Naloxone; Neurons; Pain; Phentolamine; Pons; Propranolol; Rats; Rats, Inbred Strains; Reaction Time; Yohimbine | 1990 |
Antinociceptive effects of the stereoisomers of nicotine given intrathecally in spinal rats.
Topics: Analgesia; Animals; Injections, Spinal; Male; Mecamylamine; Nicotine; Pain; Pain Measurement; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism; Yohimbine | 1990 |
Serotonergic mediation of spinal analgesia and its interaction with noradrenergic systems.
Topics: Anesthesia, Spinal; Animals; Cats; Female; Injections, Intravenous; Injections, Spinal; Male; Methysergide; Naloxone; Neurons; Pain; Serotonin; Serotonin Antagonists; Yohimbine | 1990 |
Substance P-induced long-term blockade of spinal adrenergic analgesia: reversal by morphine and naloxone.
Topics: Analgesia; Animals; Clonidine; Kinetics; Male; Morphine; Naloxone; Norepinephrine; Pain; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Time Factors; Yohimbine | 1987 |
Antinociceptive effects of the 5-HT2 antagonist ritanserin in rats: evidence for an activation of descending monoaminergic pathways in the spinal cord.
Topics: Animals; Methysergide; Nociceptors; Pain; Piperidines; Rats; Receptors, Serotonin; Ritanserin; Spinal Cord; Yohimbine | 1989 |
Intrathecal clonidine suppresses noxiously evoked activity of spinal wide dynamic range neurons in cats.
Topics: Analgesics; Animals; Blood Pressure; Cats; Clonidine; Decerebrate State; Drug Combinations; Female; Injections, Spinal; Male; Morphine; Neurons; Pain; Receptors, Adrenergic, alpha; Spinal Cord; Spinothalamic Tracts; Synaptic Transmission; Yohimbine | 1989 |
Differential actions of the blockade of spinal opioid, adrenergic and serotonergic receptors on the tail-flick inhibition induced by morphine microinjected into dorsal raphe and central gray in rats.
Topics: Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mesencephalon; Methysergide; Morphine; Naloxone; Pain; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Receptors, Serotonin; Spinal Cord; Yohimbine | 1989 |
Effects of alpha 2-adrenoceptors blockade on the inhibition of the nociceptive jaw-opening reflex by the lateral reticular nucleus in rabbits.
Topics: Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Medulla Oblongata; Pain; Rabbits; Receptors, Adrenergic, alpha; Reflex; Yohimbine | 1989 |
Involvement of spinal noradrenergic system in the mechanism of an antinociceptive effect of delta-sleep-inducing peptide (DSIP).
Topics: Adrenergic Fibers; Analgesia; Animals; Delta Sleep-Inducing Peptide; Male; Mice; Pain; Phentolamine; Spinal Cord; Time Factors; Yohimbine | 1989 |
[Effects of clopheline on impulse activity of neurons in the midbrain and dorsal horn of the spinal cord].
Topics: Animals; Cats; Clonidine; Mesencephalon; Naloxone; Neurons; Nociceptors; Pain; Prazosin; Spinal Cord; Yohimbine | 1989 |
Effect of yohimbine on nociceptive threshold in normoglycemic and streptozotocin-treated hyperglycemic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male; Mice; Naloxone; Pain; Reaction Time; Sensory Thresholds; Temperature; Yohimbine | 1989 |
Noradrenergic mechanisms in mediation of stress-induced hyperalgesia in rats.
Topics: Analgesia; Animals; Clonidine; Diazepam; Norepinephrine; Pain; Rats; Receptors, Adrenergic, alpha; Stress, Physiological; Vibration; Yohimbine | 1988 |
Alpha-2 receptor blockade increases responsiveness of locus coeruleus neurons to excitatory stimulation.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Idazoxan; Injections, Intravenous; Locus Coeruleus; Male; Neurons; Nicotine; Pain; Physical Stimulation; Rats; Rats, Inbred Strains; Yohimbine | 1987 |
Spinal monoaminergic receptors mediate the antinociception produced by glutamate in the medullary lateral reticular nucleus.
Topics: Animals; Electric Stimulation; Glutamates; Glutamic Acid; Hot Temperature; Male; Methysergide; Microinjections; Naloxone; Nociceptors; Pain; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Reticular Formation; Yohimbine | 1987 |
Effects of intrathecally administered methysergide and yohimbine on microstimulation-produced antinociception in the rat.
Topics: Animals; Electric Stimulation; Foot; Male; Methysergide; Pain; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Reticular Formation; Tail; Yohimbine | 1985 |
Selective inhibition of responses of feline dorsal horn neurones to noxious cutaneous stimuli by tizanidine (DS103-282) and noradrenaline: involvement of alpha 2-adrenoceptors.
Topics: Animals; Cats; Clonidine; Female; Male; Neurons, Afferent; Norepinephrine; Pain; Receptors, Adrenergic, alpha; Sensation; Skin; Spinal Cord; Yohimbine | 1985 |
Methylnalorphinium fails to reverse naloxone-sensitive stress-induced analgesia in mice.
Topics: Analgesia; Animals; Cold Temperature; Endorphins; Male; Mice; Nalorphine; Naloxone; Nervous System; Pain; Restraint, Physical; Stress, Physiological; Synaptic Transmission; Yohimbine | 1986 |
Evidence for alpha adrenoceptor modulation of the nociceptive jaw-opening reflex in rats and rabbits.
Topics: Analgesia; Animals; Clonidine; Dental Pulp; Electromyography; Jaw; Male; Pain; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reflex; Yohimbine | 1986 |
Intrathecal morphine and clonidine: antinociceptive tolerance and cross-tolerance and effects on blood pressure.
Topics: Animals; Blood Pressure; Clonidine; Drug Administration Schedule; Drug Tolerance; Injections, Spinal; Male; Morphine; Naloxone; Pain; Rats; Rats, Inbred Strains; Reference Values; Spinal Cord; Yohimbine | 1988 |
Effects of clonidine on neuronal firing evoked by a noxious stimulus.
Topics: Animals; Clonidine; Electrophysiology; Isoquinolines; Male; Neurons; Norepinephrine; Pain; Physical Stimulation; Piperazines; Piperoxan; Rats; Rats, Inbred Strains; Stimulation, Chemical; Yohimbine | 1985 |
Alphamethyldopa analgesia: its possible mechanism of action.
Topics: Analgesics; Animals; Male; Methyldopa; Mice; Naloxone; Pain; Physostigmine; Reaction Time; Time Factors; Yohimbine | 1985 |