yersiniabactin and Neoplasms

yersiniabactin has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for yersiniabactin and Neoplasms

ArticleYear
An Engineered Probiotic Platform for Cancer Epitope-Independent Targeted Radionuclide Therapy of Solid Tumors.
    Advanced healthcare materials, 2023, Volume: 12, Issue:19

    Targeted radionuclide therapy (TRT) is an emerging therapeutic modality for the treatment of various solid cancers. Current approaches rely on the presence of cancer-specific epitopes and receptors against which a radiolabeled ligand is systemically administered to specifically deliver cytotoxic doses of α and β particles to tumors. In this proof-of-concept study, tumor-colonizing Escherichia coli Nissle 1917 (EcN) is utilized to deliver a bacteria-specific radiopharmaceutical to solid tumors in a cancer-epitope independent manner. In this microbe-based pretargeted approach, the siderophore-mediated metal uptake pathway is leveraged to selectively concentrate copper radioisotopes,

    Topics: Animals; Cell Line, Tumor; Copper; Copper Radioisotopes; Escherichia coli; Mice; Neoplasms; Probiotics; Tumor Microenvironment

2023