y 27632 has been researched along with Spinal Cord Injuries in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, Y; Chang, S | 1 |
| An, J; Chen, Z; Fan, H; Hao, D; Jiang, C; Ni, S; Tian, F; Wang, X; Wang, Z; Yang, H; Zhang, Y | 1 |
| Chen, C; Chen, X; Guo, X; Li, B; Liang, J; Ren, L; Wang, F; Wang, T; Wang, X; Wang, Z; Yuan, X; Zhao, L; Zhou, B | 1 |
| Cafferty, WB; Duffy, P; Narumiya, S; Schmandke, A; Sigworth, J; Strittmatter, SM | 1 |
| Osterhout, DJ; Siebert, JR | 1 |
| Avedissian, H; Dergham, P; Ellezam, B; Essagian, C; Lubell, WD; McKerracher, L | 1 |
| Calvert, JW; Huang, L; Louis Harkey, H; Miao, L; Sung, JK; Zhang, JH | 1 |
| Fournier, AE; Strittmatter, SM; Takizawa, BT | 1 |
| Henke-Fahle, S; Monnier, PP; Mueller, BK; Schwab, JM; Sierra, A | 1 |
| Abe, H; Fujitani, M; Hata, K; Kitajo, K; Mimura, F; Yamagishi, S; Yamashita, T | 1 |
| Chan, CC; Khodarahmi, K; Liu, J; Oschipok, LW; Steeves, JD; Sutherland, D; Tetzlaff, W | 1 |
11 other study(ies) available for y 27632 and Spinal Cord Injuries
| Article | Year |
|---|---|
The ROCK inhibitor Y-27632 ameliorates blood-spinal cord barrier disruption by reducing tight junction protein degradation via the MYPT1-MLC2 pathway after spinal cord injury in rats.
Topics: Amides; Animals; Blood-Brain Barrier; Cardiac Myosins; Enzyme Inhibitors; Male; Myosin Light Chains; Phosphorylation; Protein Phosphatase 1; Proteolysis; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Spinal Cord Injuries; Tight Junction Proteins; Tight Junctions | 2021 |
Rho Kinase Inhibitor Y27632 Improves Recovery After Spinal Cord Injury by Shifting Astrocyte Phenotype and Morphology via the ROCK/NF-κB/C3 Pathway.
Topics: Animals; Astrocytes; NF-kappa B; Phenotype; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Spinal Cord; Spinal Cord Injuries | 2022 |
miR-30b Promotes spinal cord sensory function recovery via the Sema3A/NRP-1/PlexinA1/RhoA/ROCK Pathway.
Topics: Amides; Animals; Axons; Cell Adhesion Molecules; Female; Gene Expression Regulation; Guanosine Triphosphate; MicroRNAs; Nerve Regeneration; Nerve Tissue Proteins; Neuronal Outgrowth; Neurons; Neuropilin-1; Phosphorylation; Pyridines; Rats; Rats, Wistar; rho GTP-Binding Proteins; rho-Associated Kinases; Semaphorin-3A; Sensation; Sensory Receptor Cells; Signal Transduction; Spinal Cord; Spinal Cord Injuries | 2020 |
Rho-associated kinase II (ROCKII) limits axonal growth after trauma within the adult mouse spinal cord.
Topics: Amides; Analysis of Variance; Animals; Axons; Behavior, Animal; Brain Injuries; CA1 Region, Hippocampal; Cells, Cultured; Cholera Toxin; Enzyme Inhibitors; Ganglia, Spinal; Gene Expression Regulation; Median Neuropathy; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelin Proteins; Nerve Regeneration; Neurons; Nogo Proteins; Pyridines; Receptors, Calcitonin Gene-Related Peptide; Rhizotomy; rho-Associated Kinases; Spinal Cord Injuries; Time Factors; Versicans | 2009 |
The inhibitory effects of chondroitin sulfate proteoglycans on oligodendrocytes.
Topics: Amides; Animals; Cell Adhesion; Cell Differentiation; Cells, Cultured; Chondroitin ABC Lyase; Chondroitin Sulfate Proteoglycans; Enzyme Inhibitors; Image Processing, Computer-Assisted; Immunohistochemistry; Myelin Sheath; Oligodendroglia; Proteoglycans; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Spinal Cord Injuries; Stem Cells | 2011 |
Rho signaling pathway targeted to promote spinal cord repair.
Topics: ADP Ribose Transferases; Amides; Animals; Axons; Behavior, Animal; Botulinum Toxins; Cell Separation; Enzyme Inhibitors; Female; GAP-43 Protein; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred BALB C; Motor Activity; Motor Cortex; Nerve Regeneration; Neurites; Protein Serine-Threonine Kinases; Pyridines; Rats; Recovery of Function; rho GTP-Binding Proteins; rho-Associated Kinases; RNA, Messenger; Signal Transduction; Spinal Cord Injuries; Treatment Outcome | 2002 |
A possible role of RhoA/Rho-kinase in experimental spinal cord injury in rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; ADP Ribose Transferases; Amides; Animals; Blotting, Western; Botulinum Toxins; Enzyme Inhibitors; Female; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Motor Activity; Protein Serine-Threonine Kinases; Proteins; Pyridines; Rats; Rats, Sprague-Dawley; Recovery of Function; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction; Spinal Cord Injuries | 2003 |
Rho kinase inhibition enhances axonal regeneration in the injured CNS.
Topics: ADP Ribose Transferases; Amides; Animals; Axons; Botulinum Toxins; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Female; Ganglia, Spinal; Intracellular Signaling Peptides and Proteins; Motor Activity; Myelin Proteins; Nerve Regeneration; Neurites; Nogo Proteins; PC12 Cells; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Spinal Cord Injuries | 2003 |
The Rho/ROCK pathway mediates neurite growth-inhibitory activity associated with the chondroitin sulfate proteoglycans of the CNS glial scar.
Topics: ADP Ribose Transferases; Amides; Animals; Axons; Botulinum Toxins; Cells, Cultured; Chick Embryo; Chickens; Chondroitin Sulfate Proteoglycans; Cicatrix; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Products, tat; Intracellular Signaling Peptides and Proteins; Nerve Regeneration; Neurites; Neuroglia; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred Lew; Recombinant Fusion Proteins; Retinal Ganglion Cells; rho GTP-Binding Proteins; rho-Associated Kinases; Spinal Cord Injuries | 2003 |
Wallerian degeneration involves Rho/Rho-kinase signaling.
Topics: Amides; Animals; Axons; Enzyme Activation; Enzyme Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Nogo Proteins; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Spinal Cord Injuries; Wallerian Degeneration | 2005 |
Dose-dependent beneficial and detrimental effects of ROCK inhibitor Y27632 on axonal sprouting and functional recovery after rat spinal cord injury.
Topics: Actin Depolymerizing Factors; Amides; Analysis of Variance; Animals; Axons; Behavior, Animal; Biotin; Blotting, Western; Cholera Toxin; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Motor Activity; Myosin-Light-Chain Phosphatase; Nerve Regeneration; Pain Measurement; Phosphorylation; Protein Serine-Threonine Kinases; Psychomotor Performance; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; Reaction Time; Recovery of Function; rho-Associated Kinases; Rotarod Performance Test; Spinal Cord Injuries | 2005 |