Compounds > y 27632
Page last updated: 2024-09-03

y 27632 and Reperfusion Injury

y 27632 has been researched along with Reperfusion Injury in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (50.00)29.6817
2010's9 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, L; Liu, B1
Goto, T; Kamiyama, I; Kohno, M; Ohtsuka, T; Sawafuji, M; Tasaka, S; Watanabe, M1
Ayaz, L; Canacankatan, N; Cuez, T; Gorur, A; Kacan, M; Kemal Buharalioglu, C; Korkmaz, B; Sahan Firat, S; Sari, AN; Sucu, N; Tamer Gumus, L; Tunctan, B; Unsal, D; Vezir, O1
Akbay, E; Apa, DD; Bozlu, M; Büyükafşar, K; Çayan, S; Çimen, B; Efesoy, O; Saylam, B; Tiftik, N; Ünal, ND1
Grzesk, E; Grzesk, G; Jasinski, M; Slupski, M; Szadujkis-Szadurska, K; Szadujkis-Szadurski, L; Szadujkis-Szadurski, R; Wlodarczyk, Z; Woderska, A1
Amano, H; Hirata, K; Kimura, Y; Kobayashi, T; Kuroda, S; Mikuriya, Y; Ohdan, H; Tanaka, Y; Tashiro, H; Tsutada, M1
Ahnstedt, H; Bishop, N; Cipolla, MJ; Cruden, P; Sweet, J1
Asano, N; Ishiyama, T; Kotoda, M; Matsukawa, T; Sessler, DI; Shintani, N1
de Borst, MH; Klok, PA; Kok, RJ; Lacombe, M; Meijer, DK; Moolenaar, F; Opdam, F; Poelstra, K; Prakash, J; van Goor, H1
Blaauw, N; Di Maggio, F; Groeneveld, AB; Musters, RJ; Sipkema, P; Tangelder, GJ; Versteilen, AM1
Fujita, M; Fukai, M; Furukawa, H; Jin, MB; Nakayama, M; Sakurai, T; Shimamura, T; Suzuki, T; Takeda, K; Taniguchi, M; Todo, S1
Asahara, T; Fudaba, Y; Ito, H; Mizunuma, K; Ohdan, H; Tashiro, H1
Ikeda, F; Kondo, T; Shimahara, Y; Terajima, H; Yamaoka, Y1
Fujimura, A; Kawaguchi, A; Ohmori, M1
Kurata, H; Matsumura, Y; Nakajima, A; Takaoka, M; Teraishi, K1
Atakilit, A; Frank, JA; Godzich, M; Hodnett, M; Huang, XZ; Kim, JK; Kosinski, C; Matthay, MA; Pittet, JF; Sheppard, D; Su, G; Wu, N1
Hirata, A; Honjo, M; Inatani, M; Inomata, Y; Kawaji, T; Tanihara, H; Yonemura, N1
Groeneveld, AB; Musters, RJ; Sipkema, P; van der Heijden, M; van Nieuw Amerongen, GP; Versteilen, AM1

Other Studies

18 other study(ies) available for y 27632 and Reperfusion Injury

ArticleYear
ROCK inhibitor Y‑27632 protects rats against cerebral ischemia/reperfusion‑induced behavioral deficits and hippocampal damage.
    Molecular medicine reports, 2019, Volume: 20, Issue:4

    Topics: Amides; Animals; Apoptosis; Behavior, Animal; Brain Injuries; Hippocampus; Male; Nerve Tissue Proteins; Pyridines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; rho-Associated Kinases

2019
Attenuation of lung ischemia-reperfusion injury by rho-associated kinase inhibition in a rat model of lung transplantation.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2014, Volume: 20, Issue:5

    Topics: Amides; Animals; Bronchoalveolar Lavage Fluid; Chemotaxis; Cytoprotection; Disease Models, Animal; Lung; Lung Injury; Lung Transplantation; Macrophages; Neutrophil Infiltration; Permeability; Protein Kinase Inhibitors; Pulmonary Edema; Pyridines; Rats, Inbred Lew; Reperfusion Injury; rho-Associated Kinases; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha

2014
Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ injury in rats.
    European journal of pharmacology, 2014, Jan-15, Volume: 723

    Topics: Amides; Animals; Catalase; Glutathione; Inflammation; Kidney; Male; Malondialdehyde; MAP Kinase Kinase 1; MAP Kinase Signaling System; Muscle, Skeletal; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Peroxynitrous Acid; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; rho-Associated Kinases; rhoA GTP-Binding Protein; Superoxide Dismutase; Tyrosine

2014
Rho-kinase levels in testicular ischemia-reperfusion injury and effects of its inhibitor, Y-27632, on oxidative stress, spermatogenesis, and apoptosis.
    Urology, 2014, Volume: 83, Issue:3

    Topics: Amides; Animals; Antioxidants; Apoptosis; Enzyme Inhibitors; Humans; Male; Oxidative Stress; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; rho-Associated Kinases; Spermatic Cord Torsion; Spermatogenesis; Testis

2014
Rho-kinase inhibitor reduces hypersensitivity to ANG II in human mesenteric arteries retrieved and conserved under the same conditions as transplanted organs.
    Postepy higieny i medycyny doswiadczalnej (Online), 2014, Aug-22, Volume: 68

    Topics: Amides; Angiotensin II; Cadaver; Calcium; Enzyme Inhibitors; Humans; Hypersensitivity; Mesenteric Arteries; Pyridines; Reperfusion Injury; rho-Associated Kinases; Tissue Preservation

2014
Rho-kinase inhibitor targeting the liver prevents ischemia/reperfusion injury in the steatotic liver without major systemic adversity in rats.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2015, Volume: 21, Issue:1

    Topics: Amides; Animals; Arterial Pressure; Cells, Cultured; Chemistry, Pharmaceutical; Choline Deficiency; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Fatty Liver; Hepatic Stellate Cells; Hypotension; Liposomes; Liver; Liver Circulation; Male; Portal Pressure; Protein Kinase Inhibitors; Pyridines; Rats, Wistar; Reperfusion Injury; rho-Associated Kinases; Time Factors

2015
Effects of Early Post-Ischemic Reperfusion and tPA on Cerebrovascular Function and Nitrosative Stress in Female Rats.
    Translational stroke research, 2016, Volume: 7, Issue:3

    Topics: Actins; Amides; Animals; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Fibrinolytic Agents; Infarction, Middle Cerebral Artery; Middle Cerebral Artery; Muscle, Smooth; Neutrophils; Ovariectomy; Pyridines; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; Tissue Plasminogen Activator; Tyrosine

2016
The effects of Y-27632 on pial microvessels during global brain ischemia and reperfusion in rabbits.
    BMC anesthesiology, 2017, 03-07, Volume: 17, Issue:1

    Topics: Amides; Animals; Blood Glucose; Blood Pressure; Brain Ischemia; Microvessels; Pia Mater; Propofol; Pyridines; Rabbits; Reperfusion Injury; Vasoconstriction

2017
Inhibition of renal rho kinase attenuates ischemia/reperfusion-induced injury.
    Journal of the American Society of Nephrology : JASN, 2008, Volume: 19, Issue:11

    Topics: Actins; Amides; Animals; Cell Adhesion Molecules; Chemokine CCL2; Collagen Type I; Collagen Type I, alpha 1 Chain; Drug Carriers; Gene Expression; Kidney; Male; Muramidase; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; rho-Associated Kinases; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1

2008
ρ-Kinase inhibition reduces early microvascular leukocyte accumulation in the rat kidney following ischemia-reperfusion injury: roles of nitric oxide and blood flow.
    Nephron. Experimental nephrology, 2011, Volume: 118, Issue:4

    Topics: Amides; Animals; Kidney; Leukocytes; Male; Microcirculation; Nitric Oxide; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Renal Circulation; Reperfusion Injury; rho-Associated Kinases

2011
A novel inhibitor of Rho-associated protein kinase, Y-27632, ameliorates hepatic ischemia and reperfusion injury in rats.
    Surgery, 2003, Volume: 133, Issue:2

    Topics: Alanine Transaminase; Amides; Animals; Blood Pressure; Endothelin-1; Enzyme Inhibitors; Heart Rate; Hyaluronic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Intracellular Signaling Peptides and Proteins; Liver; Liver Circulation; Male; Malondialdehyde; Peroxidase; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; rho-Associated Kinases; Survival Rate

2003
Prevention of ischemia-reperfusion-induced hepatic microcirculatory disruption by inhibiting stellate cell contraction using rock inhibitor.
    Transplantation, 2003, Mar-15, Volume: 75, Issue:5

    Topics: Amides; Animals; Cells, Cultured; Endothelin-1; Endothelium; Enzyme Inhibitors; Enzymes; Intracellular Signaling Peptides and Proteins; Ischemia; Liver; Liver Circulation; Liver Failure; Liver Transplantation; Male; Microcirculation; Mitochondria, Liver; Oxygen Consumption; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; rho-Associated Kinases

2003
Reduction of hepatic ischemia/reperfusion-induced injury by a specific ROCK/Rho kinase inhibitor Y-27632.
    The Journal of surgical research, 2003, Volume: 109, Issue:2

    Topics: Amides; Animals; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Liver; Male; Microcirculation; Models, Animal; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; rho-Associated Kinases; Transaminases

2003
Partial protective effect of Y-27632, a Rho kinase inhibitor, against hepatic ischemia-reperfusion injury in rats.
    European journal of pharmacology, 2004, Jun-16, Volume: 493, Issue:1-3

    Topics: Alanine Transaminase; Amides; Animals; Aspartate Aminotransferases; Blood Pressure; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Injections, Intravenous; Intracellular Signaling Peptides and Proteins; Liver; Liver Diseases; Male; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; rho-Associated Kinases; Time Factors

2004
Preventive effect of Y-27632, a selective Rho-kinase inhibitor, on ischemia/reperfusion-induced acute renal failure in rats.
    European journal of pharmacology, 2004, Nov-28, Volume: 505, Issue:1-3

    Topics: Acute Kidney Injury; Amides; Animals; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Function Tests; Male; Peroxidase; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; rho-Associated Kinases; Time Factors

2004
Integrin alphavbeta5 regulates lung vascular permeability and pulmonary endothelial barrier function.
    American journal of respiratory cell and molecular biology, 2007, Volume: 36, Issue:3

    Topics: Amides; Animals; Antibodies; Blood-Air Barrier; Capillary Permeability; Cattle; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Humans; Integrins; Intracellular Signaling Peptides and Proteins; Lung Diseases; Mice; Protein Serine-Threonine Kinases; Pulmonary Artery; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Vitronectin; Reperfusion Injury; rho-Associated Kinases; Stress Fibers; Ventilators, Mechanical

2007
Y-27632, a Rho-associated protein kinase inhibitor, attenuates neuronal cell death after transient retinal ischemia.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2008, Volume: 246, Issue:1

    Topics: Amides; Animals; Cell Death; Cell Survival; Endothelium, Vascular; Enzyme Inhibitors; Immunoenzyme Techniques; In Situ Nick-End Labeling; Leukocytes; Male; Neuroprotective Agents; Pyridines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Retinal Diseases; Retinal Ganglion Cells; Retinal Vessels; rho-Associated Kinases; Silver Staining

2008
Rho-kinase-dependent F-actin rearrangement is involved in the inhibition of PI3-kinase/Akt during ischemia-reperfusion-induced endothelial cell apoptosis.
    Apoptosis : an international journal on programmed cell death, 2008, Volume: 13, Issue:3

    Topics: Actins; Amides; Androstadienes; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cytochalasin D; Depsipeptides; Endothelium, Vascular; Humans; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; Reperfusion Injury; rho-Associated Kinases; Thiazolidines; Wortmannin

2008