y 27632 has been researched along with Pregnancy in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 16 (50.00) | 29.6817 |
| 2010's | 13 (40.63) | 24.3611 |
| 2020's | 3 (9.38) | 2.80 |
| Authors | Studies |
|---|---|
| Domokos, D; Falkay, G; Fülöp, F; Gáspár, R | 1 |
| Almeida, CR; Alves, JV; Auxiliadora-Martins, M; Avila-Mesquita, CD; Becari, C; Campos, LCB; Costa, RM; Couto, AES; Lima, JF; Lobato, NS; Louzada-Júnior, P; Machado, MR; Tostes, RC | 1 |
| Al-Jarallah, A; Chacko Verghese, L; Oommen, E; Oriowo, MA | 1 |
| Huang, W; Huang, Z; Li, J; Li, Y; Liao, Z; Liu, Y; Miao, L | 1 |
| Gaynullina, DK; Selivanova, EK; Shilova, LD; Shvetsova, AA; Tarasova, OS | 1 |
| Fujieda, M; Hara, M; Imadome, KI; Matsuda, A; Matsuda, G; Matsumoto, K; Morita, H; Motomura, K; Nagamatsu, T; Okada, N; Orimo, K; Sago, H; Saito, H; Tamari, M | 1 |
| Akutsu, H; Ihara, N; Ikemoto, Y; Kajiwara, K; Karibe, J; Kawasaki, T; Oishi, Y; Okamoto, A; Okamura, K; Sago, H; Samura, O; Takada, S; Tanemoto, T; Umezawa, A; Wada, S | 1 |
| Ishikawa, G; Nakai, A; Ohneda, W; Tachikawa, E; Takeshita, T; Tamura, K; Yoshie, M | 1 |
| Domokos, D; Ducza, E; Gáspár, R | 1 |
| Hsu, SH; Lai, YK; Li, YW; Liou, JY; Wang, CH; Wu, CC; Wu, KK; Yen, BL | 1 |
| Bredow, M; Brünnert, D; Ehrhardt, J; Goyal, P; Piccenini, S; Zygmunt, M | 1 |
| Hutchinson, JL; Norman, JE; Rajagopal, SP; Yuan, M | 1 |
| Ohinata, Y; Tsukiyama, T | 1 |
| Choi, JH; Jung, J; Kim, GJ; Lim, SM; Park, JW; Yoo, YI | 1 |
| Burden, H; Burgess, R; James, SE; Longo, FM; Lu, Q; Massa, SM; Xie, Y; Yang, T | 1 |
| Bueno, C; Catalina, P; Cortes, JL; Elosua, C; García-Pérez, JL; Gutierrez-Aranda, I; Leone, PE; Ligero, G; Maleno, I; Menendez, P; Montes, R; Ramos-Mejía, V; Sanchez, L | 1 |
| Goulopoulou, S; Hannan, JL; Matsumoto, T; Webb, RC | 1 |
| Jiang, M; Li, T; Li, W; Li, X; Liu, L; Liu, Z; Teng, F; Wang, J; Wang, L; Wang, X; Zhao, XY; Zhou, Q | 1 |
| Ahn, DS; Hwang, MK; Kwon, SC; Lee, YH; Oh, JH; Taggart, MJ; You, SK | 1 |
| Taylor, CW; Thornton, S; Woodcock, NA | 1 |
| Kawagishi, R; Morishige, K; Murata, Y; Sakata, M; Sawada, K; Tahara, M; Tasaka, K | 1 |
| Baker, PN; O'Hara, M; Seghier, F; Taggart, MJ; Wareing, M | 1 |
| Katoue, MG; Khan, I; Oriowo, MA | 1 |
| Abman, SH; Grover, TR; Parker, TA; Roe, G | 1 |
| Friel, AM; Morrison, JJ; O'reilly, MW; Sexton, DJ; Smith, TJ | 1 |
| Gao, Y; Longo, LD; Negash, S; Portugal, AD; Usha Raj, J; Zhou, W | 1 |
| Kawamata, M; Kimura, T; Nishimori, K; Sugimoto, Y; Tonomura, Y; Yanagisawa, T | 1 |
| Hashimoto, K; Morishige, K; Murata, Y; Ogata, S; Shimizu, S; Tahara, M; Tasaka, K | 1 |
| Chakraborty, C; Chirpac, A; Lala, PK; Nicola, C | 1 |
| Fafet, P; Maudelonde, T; Rebouissou, C; Vignais, ML | 1 |
| Cairns, M; Friel, AM; Moran, CJ; Morrison, JJ; Smith, TJ | 1 |
| Ikebuchi, Y; Kawagishi, R; Morishige, K; Murata, Y; Sawada, K; Tahara, M; Tasaka, K | 1 |
32 other study(ies) available for y 27632 and Pregnancy
| Article | Year |
|---|---|
Effects of newly synthetized isoquinoline derivatives on rat uterine contractility and ROCK II activity.
Topics: Animals; Dose-Response Relationship, Drug; Female; Isoquinolines; Molecular Structure; Pregnancy; Protein Kinase Inhibitors; Rats; rho-Associated Kinases; Structure-Activity Relationship; Uterine Contraction | 2018 |
Inhibition of IL-6 signaling prevents serum-induced umbilical cord artery dysfunction from patients with severe COVID-19.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Arteries; COVID-19; Cytokines; Female; Humans; Interleukin-6; Pregnancy; Reactive Oxygen Species; rho-Associated Kinases; Serotonin; Umbilical Cord | 2023 |
Role of Extracellular Calcium and Calcium Sensitization in the Anti-Contractile Effect of Perivascular Adipose Tissue in Pregnant Rat Aorta.
Topics: Adipose Tissue; Amides; Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Female; Indoles; Maleimides; Nifedipine; Pregnancy; Pyridines; Rats, Sprague-Dawley; Serotonin; Vasoconstriction | 2019 |
Inhibition of RhoA Activity Does Not Rescue Synaptic Development Abnormalities and Long-Term Cognitive Impairment After Sevoflurane Exposure.
Topics: Amides; Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Cognitive Dysfunction; Dendritic Spines; Enzyme Activation; Enzyme Inhibitors; Female; Hippocampus; Long-Term Potentiation; Male; Open Field Test; Pregnancy; Pyridines; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Sevoflurane; Signal Transduction; Synapses | 2021 |
Intrauterine growth restriction weakens anticontractile influence of NO in coronary arteries of adult rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Coronary Vessels; Disease Models, Animal; Female; Fetal Growth Retardation; Male; Mesenteric Arteries; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase Type III; Pregnancy; Pyridines; Rats, Wistar; rho-Associated Kinases | 2021 |
A Rho-associated coiled-coil containing kinases (ROCK) inhibitor, Y-27632, enhances adhesion, viability and differentiation of human term placenta-derived trophoblasts in vitro.
Topics: Amides; Apoptosis; Cell Adhesion; Cell Differentiation; Cell Proliferation; Cells, Cultured; Female; Humans; Placenta; Pregnancy; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Trophoblasts | 2017 |
Fetal Therapy Model of Myelomeningocele with Three-Dimensional Skin Using Amniotic Fluid Cell-Derived Induced Pluripotent Stem Cells.
Topics: Amides; Amniotic Fluid; Animals; Cell Adhesion Molecules; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Cellular Reprogramming; Disease Models, Animal; Down Syndrome; Epidermal Cells; Epidermal Growth Factor; Epidermis; Exome Sequencing; Extracellular Matrix Proteins; Female; Fetal Therapies; Fetofetal Transfusion; Humans; Induced Pluripotent Stem Cells; Karyotyping; Keratin-14; Keratinocytes; Meningomyelocele; Polymorphism, Single Nucleotide; Pregnancy; Pyridines; Rats; Skin; Transcription Factors | 2017 |
Glibenclamide inhibits NLRP3 inflammasome-mediated IL-1β secretion in human trophoblasts.
Topics: Amides; Bucladesine; Caspase 1; Cell Differentiation; Cells, Cultured; Female; Glyburide; Humans; Inflammasomes; Interleukin-1beta; NLR Family, Pyrin Domain-Containing 3 Protein; Potassium Channel Blockers; Potassium Ionophores; Pregnancy; Pyridines; Trophoblasts; U937 Cells | 2017 |
RhoA and Rho-kinase inhibitors modulate cervical resistance: The possible role of RhoA/Rho-kinase signalling pathway in cervical ripening and contractility.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cervical Ripening; Cervix Uteri; Female; In Vitro Techniques; Muscle Contraction; Pregnancy; Pyridines; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; RNA, Messenger; Simvastatin | 2019 |
The role of RhoA kinase inhibition in human placenta-derived multipotent cells on neural phenotype and cell survival.
Topics: Adipogenesis; Amides; Cell Cycle; Cell Differentiation; Cell Proliferation; Cell Shape; Cell Survival; Cytoskeleton; Epithelial Cells; Female; Gene Expression Regulation; Humans; Intermediate Filament Proteins; Microtubule-Associated Proteins; Multipotent Stem Cells; Myosin Type II; Nerve Tissue Proteins; Nestin; Neurons; Osteogenesis; Phenotype; Placenta; Pregnancy; Pyridines; rho-Associated Kinases | 2013 |
Cytokine IL-6 secretion by trophoblasts regulated via sphingosine-1-phosphate receptor 2 involving Rho/Rho-kinase and Rac1 signaling pathways.
Topics: Amides; Aminoquinolines; Cell Line; Chromones; Cycloheximide; Dactinomycin; Female; Humans; Interleukin-6; Lysophospholipids; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Pregnancy; Pyrazoles; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Receptors, Lysosphingolipid; rho GTP-Binding Proteins; rho-Associated Kinases; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Trophoblasts | 2013 |
Lipopolysaccharide promotes contraction of uterine myocytes via activation of Rho/ROCK signaling pathways.
Topics: Amides; Blotting, Western; Cell Line; Cells, Cultured; Female; Humans; Imidazoles; Infant, Newborn; Lipopolysaccharides; Muscle Cells; Muscle Contraction; Oxadiazoles; Pregnancy; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Uterine Contraction; Uterus | 2014 |
Establishment of trophoblast stem cells under defined culture conditions in mice.
Topics: Activins; Amides; Animals; Blastocyst; Cell Differentiation; Cell Lineage; Culture Media; Ectoderm; Embryo Implantation; Embryonic Development; Embryonic Stem Cells; Female; Fibroblast Growth Factor 2; Heterocyclic Compounds, 3-Ring; Humans; Mice; Placenta; Pregnancy; Pyridines; Trophoblasts | 2014 |
Microenvironmental Interaction Between Hypoxia and Endothelial Cells Controls the Migration Ability of Placenta-Derived Mesenchymal Stem Cells via α4 Integrin and Rho Signaling.
Topics: Amides; Blotting, Western; Cell Hypoxia; Cell Line; Cell Movement; Cells, Cultured; Cellular Microenvironment; Coculture Techniques; Enzyme Inhibitors; Female; Fibroblasts; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Integrin alpha4; Matrix Metalloproteinase 2; Mesenchymal Stem Cells; Placenta; Pregnancy; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; RNA Interference; Signal Transduction | 2016 |
Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants.
Topics: Amides; Aniline Compounds; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Benzimidazoles; Cells, Cultured; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Female; Glutathione Transferase; Hippocampus; Microtubule-Associated Proteins; Neurites; Neurons; Neuroprotective Agents; Pregnancy; Pyridines; Rats; rhoA GTP-Binding Protein; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Mesenchymal stem cells facilitate the derivation of human embryonic stem cells from cryopreserved poor-quality embryos.
Topics: Amides; Animals; Cell Line; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Stem Cells; Female; Humans; Mesenchymal Stem Cells; Mice; Pregnancy; Pyridines; rho-Associated Kinases | 2009 |
Pregnancy reduces RhoA/Rho kinase and protein kinase C signaling pathways downstream of thromboxane receptor activation in the rat uterine artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Enzyme Inhibitors; Female; Indoles; Maleimides; Mesenteric Arteries; Pregnancy; Pregnancy, Animal; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; rho-Associated Kinases; Signal Transduction; Uterine Artery; Uterus; Vasoconstrictor Agents | 2012 |
Derivation of germline competent rat embryonic stem cells from DA rats.
Topics: Amides; Animals; Biomarkers; Blastocyst; Cells, Cultured; Chimera; Culture Media; Culture Media, Serum-Free; Embryonic Stem Cells; Enzyme Inhibitors; Female; Pluripotent Stem Cells; Pregnancy; Pyrazoles; Pyridines; Rats; Rats, Inbred F344; Rats, Inbred Strains; Thiocarbamates; Thiosemicarbazones | 2012 |
Inhibition of rho-associated kinase reduces MLC20 phosphorylation and contractility of intact myometrium and attenuates agonist-induced Ca2+ sensitization of force of permeabilized rat myometrium.
Topics: Amides; Animals; Calcium; Carbachol; Cholinergic Agents; Enzyme Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Myometrium; Myosin Light Chains; Naphthalenes; Permeability; Phosphorylation; Pregnancy; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Uterine Contraction | 2003 |
Effect of an oxytocin receptor antagonist and rho kinase inhibitor on the [Ca++]i sensitivity of human myometrium.
Topics: Adult; Amides; Benzoxazines; Calcium; Calcium Signaling; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Intracellular Membranes; Intracellular Signaling Peptides and Proteins; Myometrium; Osmolar Concentration; Oxazines; Oxytocin; Piperidines; Pregnancy; Protein Serine-Threonine Kinases; Pyridines; Receptors, Oxytocin; rho-Associated Kinases; Uterine Contraction | 2004 |
Tocolytic effect of a Rho-kinase inhibitor in a mouse model of lipopolysaccharide-induced preterm delivery.
Topics: Amides; Animals; Cells, Cultured; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Mice; Mice, Inbred C3H; Obstetric Labor, Premature; Pregnancy; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Tocolytic Agents | 2005 |
The involvement of Rho-associated kinases in agonist-dependent contractions of human maternal and placental arteries at term gestation.
Topics: Amides; Arteries; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Female; Humans; Intracellular Signaling Peptides and Proteins; Marine Toxins; Muscle Relaxants, Central; Muscle, Smooth, Vascular; Myometrium; Omentum; Oxazoles; Phosphoprotein Phosphatases; Placenta; Pregnancy; Pregnancy Trimester, Third; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Vasoconstriction | 2005 |
Pregnancy-induced modulation of calcium mobilization and down-regulation of Rho-kinase expression contribute to attenuated vasopressin-induced contraction of the rat aorta.
Topics: Amides; Animals; Aorta; Arginine Vasopressin; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Nifedipine; Pregnancy; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents | 2006 |
Rho kinase activation maintains high pulmonary vascular resistance in the ovine fetal lung.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Lung; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pregnancy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pulmonary Circulation; Pyridines; rho-Associated Kinases; Sheep; Signal Transduction; Vascular Resistance | 2006 |
Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre eclamptic pregnancies and functional role in isoprostane-induced vasoconstriction.
Topics: Acute-Phase Proteins; Amides; Analysis of Variance; Case-Control Studies; Dinoprost; Dinoprostone; Female; Humans; Intracellular Signaling Peptides and Proteins; Isoprostanes; Muscle, Smooth, Vascular; Pre-Eclampsia; Pregnancy; Protein Isoforms; Protein Serine-Threonine Kinases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; RNA, Messenger; Tissue Culture Techniques; Umbilical Arteries; Vasoconstrictor Agents | 2006 |
Role of Rho kinases in PKG-mediated relaxation of pulmonary arteries of fetal lambs exposed to chronic high altitude hypoxia.
Topics: Amides; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Fetus; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Hypoxia; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Oxygen; Pregnancy; Protein Serine-Threonine Kinases; Pulmonary Artery; Pulmonary Circulation; Pyridines; rho-Associated Kinases; RNA, Messenger; Sheep; Vasodilation | 2007 |
Oxytocin-induced phasic and tonic contractions are modulated by the contractile machinery rather than the quantity of oxytocin receptor.
Topics: Amides; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calpain; Diestrus; Enzyme Inhibitors; Estrus; Female; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxytocin; Pregnancy; Protein Serine-Threonine Kinases; Pyridines; Receptors, Oxytocin; Receptors, Prostaglandin; rho-Associated Kinases; RNA, Messenger; Uterine Contraction; Uterus; Verapamil | 2007 |
Involvement of nuclear factor-kB activation through RhoA/Rho-kinase pathway in LPS-induced IL-8 production in human cervical stromal cells.
Topics: ADP Ribose Transferases; Adult; Amides; Botulinum Toxins; Cells, Cultured; Cervical Ripening; Cervix Uteri; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Humans; I-kappa B Proteins; Interleukin-1beta; Interleukin-8; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; NF-kappa B; NF-KappaB Inhibitor alpha; Nitriles; Phosphorylation; Pregnancy; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA Interference; RNA, Small Interfering; Stromal Cells; Sulfones; Time Factors; Transcription, Genetic | 2007 |
Roles of Rho guanosine 5'-triphosphatase A, Rho kinases, and extracellular signal regulated kinase (1/2) in prostaglandin E2-mediated migration of first-trimester human extravillous trophoblast.
Topics: Amides; Butadienes; Cell Line; Cell Movement; Chorionic Villi; Dinoprostone; Enzyme Inhibitors; Female; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Pregnancy; Pregnancy Trimester, First; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Small Interfering; Trophoblasts | 2008 |
Opposite effects of transforming growth factor-beta activation and rho-associated kinase inhibition on human trophoblast migration in a reconstituted placental-endometrial coculture system.
Topics: Adult; Amides; Cell Adhesion; Cell Movement; Cells, Cultured; Coculture Techniques; Decidua; Endometrium; Enzyme Inhibitors; Female; Humans; Placenta; Pregnancy; Pyridines; rho-Associated Kinases; Signal Transduction; Transforming Growth Factor beta; Trophoblasts | 2008 |
Expression and modulation of Rho kinase in human pregnant myometrium.
Topics: Adult; Amides; Calcium Channel Blockers; Enzyme Inhibitors; Female; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Myometrium; Nifedipine; Pregnancy; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein | 2002 |
RhoA/Rho-kinase cascade is involved in oxytocin-induced rat uterine contraction.
Topics: Amides; Animals; Calcium; Enzyme Inhibitors; Female; Immunoblotting; In Vitro Techniques; Indicators and Reagents; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Myosin Light Chains; Oxytocin; Phosphorylation; Pregnancy; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Transcription, Genetic; Uterine Contraction; Uterus | 2002 |