y 27632 has been researched along with Neoplasm Metastasis in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 7 (46.67) | 29.6817 |
| 2010's | 7 (46.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bell, JL; Haak, AJ; Kirchhoff, PD; Larsen, SD; Neubig, RR; Wade, SM | 1 |
| Hutchinson, RC; Krabbe, LM; Margulis, V; Sanli, O; Woldu, SL | 1 |
| Biemond, I; de Rooij, K; Hardwick, JC; Hommes, DW; Hoogenboom, JP; Jacobs, RJ; Kodach, LL; Liv, N; Morreau, H; Offerhaus, GJ; Peppelenbosch, MP; Ten Dijke, P; van den Brink, GR; van Noesel, CJ; van Wezel, T; Verspaget, HW; Voorneveld, PW; Zonnevylle, AC | 1 |
| Kurniawan, NA; Lim, CT; Sun, W | 1 |
| Bhandary, L; Boggs, AE; Chakrabarti, KR; Charpentier, MS; Martin, SS; Thompson, KN; Vitolo, MI; Whipple, RA | 1 |
| Arbab, AS; Borin, TF; Coimbra, VB; de Oliveira, JG; Fabri, VA; Ferreira, LC; Gelaleti, GB; Iskander, AS; Jardim-Perassi, BV; Moschetta, MG; Shankar, A; Varma, NR; Zuccari, DA | 1 |
| Furukawa, S; Handa, H; Hashimoto, A; Hashimoto, S; Mikami, S; Oikawa, T; Okada, Y; Onodera, Y; Oya, M; Sabe, H; Sugino, H; Yoshikawa, A | 1 |
| Bidaud, A; Grise, F; Moreau, V | 1 |
| Gutkind, JS; Hitsuda, Y; Igishi, T; Matsumoto, S; Mikami, M; Murakami, K; Nakanishi, H; Shigeoka, Y; Shimizu, E; Yasuda, K | 1 |
| Bakker, A; Bronson, RT; Contreras, B; Ewen, ME; Hunt, JL; Iwanaga, T; Loda, M; Noda, M; Takahashi, C; Takegami, Y | 1 |
| Chen, YH; Fang, WG; Li, B; Tan, ZM; Zhao, WD; Zhu, L | 1 |
| Chen, XS; Han, LZ; Li, QG; Qiu, F; Xi, ZF; Xia, Q; Xue, F; Zhang, JJ; Zhang, M | 1 |
| Akedo, H; Ishizaki, T; Itoh, K; Narumiya, S; Uehata, M; Yoshioka, K | 1 |
| Bradshaw, D; Murphy, C; Myers, CE; Ramos, S; Somlyo, AP; Somlyo, AV | 1 |
| Hirohashi, S; Sakamoto, M; Takamura, M | 1 |
3 review(s) available for y 27632 and Neoplasm Metastasis
| Article | Year |
|---|---|
The Rho GTPase signalling pathway in urothelial carcinoma.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Camellia sinensis; Carcinoma, Transitional Cell; Enzyme Inhibitors; Humans; Neoplasm Metastasis; Plant Extracts; Protein Kinase Inhibitors; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Urinary Bladder Neoplasms | 2018 |
Rho GTPases in hepatocellular carcinoma.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Carcinoma, Hepatocellular; Disease Progression; Farnesyltranstransferase; Humans; Liver Neoplasms; Neoplasm Metastasis; Pyridines; rho GTP-Binding Proteins; Signal Transduction | 2009 |
[Recent progress in study of mechanism of invasion and metastasis of hepatocellular carcinoma].
Topics: Amides; Animals; Antigens, CD; Cadherins; Carcinoma, Hepatocellular; Enzyme Inhibitors; Humans; Integrin alpha6beta1; Integrins; Intracellular Signaling Peptides and Proteins; Kangai-1 Protein; Liver Neoplasms; Matrix Metalloproteinases; Membrane Glycoproteins; Monomeric GTP-Binding Proteins; Neoplasm Invasiveness; Neoplasm Metastasis; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pyridines; rho-Associated Kinases; Transcription Factors | 2001 |
12 other study(ies) available for y 27632 and Neoplasm Metastasis
| Article | Year |
|---|---|
Optimization of novel nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents.
Topics: Amides; Anilides; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Molecular Structure; Neoplasm Metastasis; Nipecotic Acids; Oncogene Proteins, Fusion; Prostatic Neoplasms; rhoA GTP-Binding Protein; Serum Response Factor; Structure-Activity Relationship; Trans-Activators | 2013 |
Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK.
Topics: Aged; Amides; Animals; Bone Morphogenetic Proteins; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Disease Models, Animal; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Female; Heterografts; Humans; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Metastasis; Pyridines; rho-Associated Kinases; Signal Transduction; Smad4 Protein; Survival Rate | 2014 |
Mechanistic adaptability of cancer cells strongly affects anti-migratory drug efficacy.
Topics: Amides; Antineoplastic Agents; Breast Neoplasms; Cell Movement; Cytochalasin D; Dipeptides; Extracellular Matrix; Female; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Microscopy, Confocal; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplastic Cells, Circulating; Nocodazole; Pyridines; Statistics, Nonparametric; Time-Lapse Imaging | 2014 |
ROCK inhibition promotes microtentacles that enhance reattachment of breast cancer cells.
Topics: Actomyosin; Amides; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cytoskeleton; Female; Humans; Neoplasm Metastasis; Neoplastic Cells, Circulating; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases | 2015 |
Melatonin decreases breast cancer metastasis by modulating Rho-associated kinase protein-1 expression.
Topics: Amides; Animals; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Melatonin; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Proteins; Pyridines; rho-Associated Kinases; Single Photon Emission Computed Tomography Computed Tomography; Xenograft Model Antitumor Assays | 2016 |
Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Adult; Aged; Aged, 80 and over; Amides; Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Female; GTP-Binding Protein alpha Subunits, G12-G13; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Immunohistochemistry; Indoles; Isoxazoles; Kidney Neoplasms; Lysophospholipids; Male; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Nerve Tissue Proteins; Propionates; Pyridines; Pyrroles; Receptors, Lysophosphatidic Acid; Signal Transduction; Sirolimus; Sunitinib; Triazoles | 2016 |
Enhancement of cisplatin-induced cytotoxicity by ROCK inhibitor through suppression of focal adhesion kinase-independent mechanism in lung carcinoma cells.
Topics: Amides; Blotting, Western; Carcinoma; Cell Line, Tumor; Cisplatin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Neoplasm Metastasis; Phosphorylation; Plasmids; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; rho-Associated Kinases; Signal Transduction; Time Factors; Transfection; Tyrosine | 2003 |
Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor.
Topics: Adenocarcinoma; Adenoma; Adrenocorticotropic Hormone; Amides; Animals; Carcinoma, Medullary; Enzyme Inhibitors; Genes, ras; Heterozygote; Mice; Mice, Mutant Strains; Mice, Nude; Neoplasm Metastasis; Neuroendocrine Tumors; Proto-Oncogene Mas; Pyridines; Retinoblastoma Protein; rhoA GTP-Binding Protein; Signal Transduction; Thyroid Neoplasms | 2006 |
Involvement of Rho/ROCK signalling in small cell lung cancer migration through human brain microvascular endothelial cells.
Topics: Amides; Brain Neoplasms; Carcinoma, Small Cell; Cell Line, Tumor; Cell Movement; Cytoskeleton; Endothelial Cells; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Dominant; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Neoplasm Metastasis; Neoplasm Proteins; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Signal Transduction | 2006 |
Rho signaling inhibitor, Y-27632, inhibits invasiveness of metastastic hepatocellular carcinoma in a mouse model.
Topics: Actins; Amides; Animals; Apoptosis; Cytoskeleton; Enzyme Inhibitors; Female; Liver Neoplasms, Experimental; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Pyridines; ras Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; rhoC GTP-Binding Protein | 2007 |
An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.
Topics: Amides; Animals; Cell Adhesion; Cell Transformation, Neoplastic; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases; Transfection; Tumor Cells, Cultured | 1999 |
Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells.
Topics: Amides; Animals; Azepines; Cattle; Cell Division; Cells, Cultured; Chemotaxis; Endothelium, Vascular; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Transgenic; Myosin-Light-Chain Kinase; Myosin-Light-Chain Phosphatase; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Physiologic; Phosphoprotein Phosphatases; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |