y 27632 and Muscle Relaxation

Topics: Acetanilides; Adenylyl Cyclase Inhibitors; Aged; Amides; Animals; Carbachol; Cyclic AMP; Female; Humans; Indoles; Isoquinolines; Male; Maleimides; Muscle Relaxation; Muscle, Smooth; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Signal Transduction; Sulfonamides; Swine; Thiazoles; Urinary Bladder; Urological Agents

Topics: Amides; Animals; Calcium; Enzyme Inhibitors; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Pyridines; Rabbits; Renal Artery; rho-Associated Kinases

Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Adult; Aged; Amides; Animals; Female; Humans; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Male; Middle Aged; Muscle Relaxation; Peptides; Phosphorylation; Pyridines; Rats, Wistar; Receptors, Adrenergic, beta-3; rho-Associated Kinases; Species Specificity; Thiazoles; Urinary Bladder

Topics: Acetylcholine; Amides; Anesthetics, Inhalation; Animals; Asthma; Bronchi; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Isoflurane; Male; Muscle Relaxation; Muscle, Smooth; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction

Topics: Adenine; Amides; Animals; Enzyme Activation; Gastric Fundus; Glyburide; Hydrogen Sulfide; In Vitro Techniques; Male; Marine Toxins; Mice; Muscle Relaxation; Myosin-Light-Chain Phosphatase; NG-Nitroarginine Methyl Ester; omega-Conotoxins; Oxazoles; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Tetrodotoxin

Topics: Amides; Diabetes Mellitus; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth; Penis; Pyridines; rho-Associated Kinases; Serotonin

Topics: Amides; Animals; Calcium Signaling; Carbachol; Cholinergic Agonists; Colon; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; In Vitro Techniques; Jejunum; Marine Toxins; Membrane Proteins; Mice; Mice, Knockout; Muscle Relaxation; Muscle, Smooth; Mutation; Myosin-Light-Chain Kinase; Myosin-Light-Chain Phosphatase; Oxazoles; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Pyridines; rho-Associated Kinases; Time Factors

Topics: Alkyl and Aryl Transferases; Amides; Animals; Bronchial Hyperreactivity; Enzyme Inhibitors; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Muscle Relaxation; Muscle, Smooth; Prenylation; Pyridines; rhoA GTP-Binding Protein

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Penis; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Species Specificity; Up-Regulation

Topics: Amides; Animals; Carotid Artery, Common; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; Hypertension; In Vitro Techniques; Muscle Contraction; Muscle Proteins; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Contraction; Peroxides; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Thromboxane; rho-Associated Kinases; Signal Transduction

Topics: Amides; Animals; Asthma; Azepines; Calcium; Imidazoles; In Vitro Techniques; Molecular Targeted Therapy; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myosin-Light-Chain Kinase; Naphthalenes; Phosphorylation; Pyridines; rho-Associated Kinases; Sheep; Signal Transduction; Trachea

Topics: Amides; Calcium; Carbachol; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Maleimides; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Protein Kinase C; Pyridines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; rho-Associated Kinases; Signal Transduction; Urinary Bladder

Topics: Amides; Animals; Clitoris; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Guanylate Cyclase; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle Relaxation; Protein Serine-Threonine Kinases; Pyrazoles; Pyridines; Rabbits; Receptors, Cytoplasmic and Nuclear; rho-Associated Kinases; Soluble Guanylyl Cyclase; Vagina

Topics: Adrenergic alpha-Agonists; Amides; Animals; Calcium; Enzyme Inhibitors; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Male; Maleimides; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Penis; Phenylephrine; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; Type C Phospholipases

Topics: Amides; Animals; Enzyme Inhibitors; Hypertrophy; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoenzymes; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocytes, Smooth Muscle; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; RNA, Messenger; Urinary Bladder; Urinary Bladder Neck Obstruction

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Muscle Relaxation; Penis; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases

Topics: Aging; Amides; Animals; Animals, Newborn; Enzyme Inhibitors; Female; Fetus; Gene Expression Regulation, Developmental; Intracellular Signaling Peptides and Proteins; Muscle Relaxation; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Myosin-Light-Chain Phosphatase; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Protein Subunits; Pulmonary Artery; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases

Topics: Actins; Amides; Animals; Aorta, Thoracic; Blotting, Western; Hot Temperature; HSP72 Heat-Shock Proteins; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myosin Light Chains; Phenylephrine; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Shock; Vasoconstrictor Agents

Topics: Amides; Anal Canal; Animals; Disease Models, Animal; Enzyme Inhibitors; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle Hypertonia; Muscle Relaxation; Muscle, Smooth; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Tetrodotoxin; Treatment Outcome

Topics: ADP Ribose Transferases; Amides; Anal Canal; Animals; Botulinum Toxins; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Guanine Nucleotide Dissociation Inhibitors; Indoles; Intracellular Signaling Peptides and Proteins; Male; Maleimides; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocytes, Smooth Muscle; Myosin Light Chains; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Rectum; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction

Topics: Aged; Amides; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Erectile Dysfunction; Humans; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Penile Erection; Penis; Piperazines; Purines; Pyridines; Sildenafil Citrate; Sulfones

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenergic alpha-Agonists; Amides; Animals; Antihypertensive Agents; Calcium Channel Agonists; Clitoris; Dose-Response Relationship, Drug; Endothelin-1; Female; Isometric Contraction; Models, Animal; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Oligopeptides; Peptides, Cyclic; Phenylephrine; Piperidines; Potassium; Pyridines; Rabbits; Urinary Bladder, Overactive; Vasodilator Agents

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Amides; Animals; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Propofol; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases

Topics: Adrenergic beta-Agonists; Albuterol; Amides; Animals; Bronchoconstrictor Agents; Bronchodilator Agents; Cattle; Intracellular Signaling Peptides and Proteins; Methacholine Chloride; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth; Protein Serine-Threonine Kinases; Pyridines; Receptors, Adrenergic, beta-2; rho-Associated Kinases; Terbutaline; Trachea