y 27632 has been researched along with Invasiveness, Neoplasm in 32 studies
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (3.13) | 18.2507 |
2000's | 11 (34.38) | 29.6817 |
2010's | 18 (56.25) | 24.3611 |
2020's | 2 (6.25) | 2.80 |
Authors | Studies |
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Baron, C; Besson, P; Bon, E; Brisson, L; Chadet, S; Lemoine, R; Lopez-Charcas, O; Moussata, D; Ouaissi, M; Poisson, L; Roger, S | 1 |
Idiris, A; Kumagai, H; Miyagi, Y; Miyazaki, K; Okamoto, R; Togo, S | 1 |
Cutiongco, MF; Gadegaard, N; Jagiełło, A; Kamphorst, JJ; Mackay, G; McGarry, L; Michalopoulou, E; Munro, J; Olson, MF; Pajic, M; Rath, N; Sumpton, D; Timpson, P; Unbekandt, M; Vennin, C | 1 |
Asghar, MY; Kemppainen, K; Lassila, T; Törnquist, K | 1 |
Bei, JX; Chen, L; Chen, MY; Feng, L; Li, X; Lian, YF; Qi, XK; Wang, Z; Xiang, T; Xiao, J; Yuan, J; Zeng, YX; Zhang, J; Zhang, Y | 1 |
Bratton, MR; Carriere, PP; Llopis, SD; Preyan, LC; Skripnikova, E; Tilghman, SL; Townley, I; Wang, G; Williams, CC; Zhang, Q; Zhong, Q; Zou, J | 1 |
Dwinell, MB; Hauser, AD; Roy, I; Williams, CL; Wilson, JM; Zimmerman, NP | 1 |
Chen, R; Cheng, Y; Geng, L; Li, Z; Zhang, Y | 1 |
Kurniawan, NA; Lim, CT; Sun, W | 1 |
Gu, SY; Li, Q; Li, XY; Liu, GL; Wang, YZ; Wu, X; Zhang, JG; Zhang, QD; Zhu, GH | 1 |
Belshaw, S; Bower, J; Crighton, D; Croft, DR; Drysdale, M; McArthur, D; McConnell, P; Mezna, M; Olson, MF; Pannifer, A; Schüttelkopf, AW; Sime, M; Unbekandt, M | 1 |
Jiang, L; Luo, W; Wen, J | 1 |
Liu, HB; Liu, J; Wang, ZM; Yang, DS; Ye, M; Zhang, YF | 1 |
Furukawa, S; Handa, H; Hashimoto, A; Hashimoto, S; Mikami, S; Oikawa, T; Okada, Y; Onodera, Y; Oya, M; Sabe, H; Sugino, H; Yoshikawa, A | 1 |
Bifulco, M; Laezza, C; Malfitano, AM; Pisanti, S | 1 |
Chang, HR; Chen, SL; Huang, HP; Hung, TW; Kao, YL; Lian, JD; Wang, CJ; Wu, SW | 1 |
Astuccio, M; Bryan, B; Callahan, W; Fellows, K; Gleason, D; Goodrow, C; Johnson, A; Lahey, D; Le, L; Monfredo, N; Ouellette, L; Partington, A; Routhier, A; Simone, P; Smith, A; Sullivan, K; Vezuli, B; West, E; Zhidro, S; Zohni, M | 1 |
Besson, A; Concha, C | 1 |
Boakes, A; Crighton, D; Heikkila, T; Kaye, SJ; Mezna, M; Olson, MF; Pang, L; Rushbrooke, M; Schroder, E; Turnbull, A; Wheatley, E | 1 |
Cho, KH; Han, JW; Jeong, KJ; Kang, J; Kim, YK; Lee, HY; Lee, J; Park, CG; Park, SY; Sohn, JS | 1 |
Chang, J; Dang, D; Lee, C; Ramos, DM; Siu, A | 1 |
Dou, KF; Li, KZ; Song, ZS; Wang, DS | 1 |
Bourguignon, LY; Diedrich, F; Gilad, E; Singleton, PA; Stern, R | 1 |
Fukushima, Y; Itoh, K; Miyahara, E; Nakagawa, H; Tamura, M; Yoshioka, K | 1 |
Beaudry, C; Berens, M; Kwan, A; Nakada, M; Rutka, JT; Rutten, F; Salhia, B | 1 |
Foran, E; Kenny, D; Lawler, K; Long, A; O'Sullivan, G | 1 |
Arihiro, K; Asahara, T; Fudaba, Y; Kobayashi, T; Miyata, Y; Ogawa, T; Okajima, M; Tashiro, H; Ushitora, Y | 1 |
Chen, XS; Han, LZ; Li, QG; Qiu, F; Xi, ZF; Xia, Q; Xue, F; Zhang, JJ; Zhang, M | 1 |
Akedo, H; Ishizaki, T; Itoh, K; Narumiya, S; Uehata, M; Yoshioka, K | 1 |
Bradshaw, D; Murphy, C; Myers, CE; Ramos, S; Somlyo, AP; Somlyo, AV | 1 |
Akedo, H; Ayaki, M; Imamura, F; Mukai, M | 1 |
Hirohashi, S; Sakamoto, M; Takamura, M | 1 |
1 review(s) available for y 27632 and Invasiveness, Neoplasm
Article | Year |
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[Recent progress in study of mechanism of invasion and metastasis of hepatocellular carcinoma].
Topics: Amides; Animals; Antigens, CD; Cadherins; Carcinoma, Hepatocellular; Enzyme Inhibitors; Humans; Integrin alpha6beta1; Integrins; Intracellular Signaling Peptides and Proteins; Kangai-1 Protein; Liver Neoplasms; Matrix Metalloproteinases; Membrane Glycoproteins; Monomeric GTP-Binding Proteins; Neoplasm Invasiveness; Neoplasm Metastasis; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pyridines; rho-Associated Kinases; Transcription Factors | 2001 |
31 other study(ies) available for y 27632 and Invasiveness, Neoplasm
Article | Year |
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Rock inhibition promotes Na
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Humans; NAV1.5 Voltage-Gated Sodium Channel; Neoplasm Invasiveness; Protein Serine-Threonine Kinases; Pyridines; Signal Transduction | 2020 |
Collective cancer cell invasion in contact with fibroblasts through integrin-α5β1/fibronectin interaction in collagen matrix.
Topics: A549 Cells; Adenocarcinoma; Amides; Benzamides; Cancer-Associated Fibroblasts; Cell Adhesion; Cell Line, Tumor; Cell Movement; Chromones; Collagen; Colonic Neoplasms; Connective Tissue; Dioxoles; Epidermal Growth Factor; Fibroblasts; Fibronectins; Humans; Immunohistochemistry; Integrin alpha5beta1; MCF-7 Cells; Morpholines; Neoplasm Invasiveness; Pyridines; Spheroids, Cellular; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2020 |
Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarcinoma Invasion and Tumor Growth.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Hydroxyphenethylamine; Amides; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Female; HEK293 Cells; Humans; Male; Mice; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Pyrazoles; Pyridines; rho-Associated Kinases; Signal Transduction | 2018 |
Sphingosine 1-phosphate attenuates MMP2 and MMP9 in human anaplastic thyroid cancer C643 cells: Importance of S1P2.
Topics: Amides; Calpain; Cell Line, Tumor; Cell Movement; Gene Expression Regulation, Neoplastic; Humans; Lysophospholipids; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Pyridines; Receptors, Lysosphingolipid; rho-Associated Kinases; Sphingosine; Thyroid Carcinoma, Anaplastic | 2018 |
SHROOM2 inhibits tumor metastasis through RhoA-ROCK pathway-dependent and -independent mechanisms in nasopharyngeal carcinoma.
Topics: Amides; Animals; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Female; Gene Knockdown Techniques; HEK293 Cells; Heterografts; Humans; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Transfection; Tumor Burden | 2019 |
Proteomic signatures of acquired letrozole resistance in breast cancer: suppressed estrogen signaling and increased cell motility and invasiveness.
Topics: Actin Cytoskeleton; Amides; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Shape; Drug Resistance, Neoplasm; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Letrozole; Mesoderm; Neoplasm Invasiveness; Neoplasm Proteins; Nitriles; Protein Kinase Inhibitors; Proteomics; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Triazoles; Vimentin | 2013 |
Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells.
Topics: 1-Methyl-3-isobutylxanthine; Amides; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Deoxycytidine; Enzyme Inhibitors; Gemcitabine; Humans; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphodiesterase Inhibitors; Pyridines; Quinolones; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; rhoC GTP-Binding Protein; Vasodilator Agents | 2015 |
RhoC mediates invasion and migration of CaSki cells through the Rho-associated serine-threonine protein kinase 1 signaling pathway.
Topics: Amides; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Female; Humans; Neoplasm Invasiveness; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; rhoC GTP-Binding Protein; Signal Transduction; Uterine Cervical Neoplasms | 2014 |
Mechanistic adaptability of cancer cells strongly affects anti-migratory drug efficacy.
Topics: Amides; Antineoplastic Agents; Breast Neoplasms; Cell Movement; Cytochalasin D; Dipeptides; Extracellular Matrix; Female; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Microscopy, Confocal; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplastic Cells, Circulating; Nocodazole; Pyridines; Statistics, Nonparametric; Time-Lapse Imaging | 2014 |
ROCK is involved in vasculogenic mimicry formation in hepatocellular carcinoma cell line.
Topics: Amides; Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Liver Neoplasms; Neoplasm Invasiveness; Neovascularization, Pathologic; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein | 2014 |
A novel small-molecule MRCK inhibitor blocks cancer cell invasion.
Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Humans; Myotonin-Protein Kinase; Neoplasm Invasiveness; Protein Kinase Inhibitors; Pyrazoles; Pyridines; rho-Associated Kinases | 2014 |
Rho‑associated kinase inhibitor, Y‑27632, inhibits the invasion and proliferation of T24 and 5367 bladder cancer cells.
Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Myosin-Light-Chain Kinase; Neoplasm Invasiveness; Phosphorylation; Protein Processing, Post-Translational; Pyridines; rho-Associated Kinases; Signal Transduction; Urinary Bladder Neoplasms | 2015 |
ROCK inhibitor Y-27632 inhibits the growth, migration, and invasion of Tca8113 and CAL-27 cells in tongue squamous cell carcinoma.
Topics: Amides; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Shape; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Humans; Neoplasm Invasiveness; Pyridines; rho-Associated Kinases; Time Factors; Tongue Neoplasms | 2016 |
Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Adult; Aged; Aged, 80 and over; Amides; Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Female; GTP-Binding Protein alpha Subunits, G12-G13; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Immunohistochemistry; Indoles; Isoxazoles; Kidney Neoplasms; Lysophospholipids; Male; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Nerve Tissue Proteins; Propionates; Pyridines; Pyrroles; Receptors, Lysophosphatidic Acid; Signal Transduction; Sirolimus; Sunitinib; Triazoles | 2016 |
The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway.
Topics: Actins; Amides; Arachidonic Acids; Blotting, Western; Breast Neoplasms; Cannabinoids; Cell Membrane; Cell Movement; Cytoskeleton; Cytosol; Female; Fluorescent Antibody Technique; Humans; Mevalonic Acid; Neoplasm Invasiveness; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2008 |
The suppressive effect of Rho kinase inhibitor, Y-27632, on oncogenic Ras/RhoA induced invasion/migration of human bladder cancer TSGH cells.
Topics: Aged; Aged, 80 and over; Amides; Cell Line, Tumor; Cell Movement; Cytoskeleton; Female; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Neoplasm Invasiveness; NF-kappa B; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; ras Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Transfection; Urinary Bladder Neoplasms | 2010 |
Pharmacological inhibition of Rho-kinase signaling with Y-27632 blocks melanoma tumor growth.
Topics: Amides; Animals; Cell Line, Tumor; Humans; Injections, Intraperitoneal; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases | 2010 |
p27Kip1 is needed...for glioma invasion.
Topics: Amides; Animals; Cell Line, Tumor; Cell Movement; Cyclin-Dependent Kinase Inhibitor p27; Glioma; Neoplasm Invasiveness; Platelet-Derived Growth Factor; Protein Structure, Tertiary; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein | 2010 |
Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasion.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Catalytic Domain; Cell Line, Tumor; Collagen; Crystallography, X-Ray; Drug Combinations; Extracellular Matrix; Humans; Inhibitory Concentration 50; Laminin; Models, Molecular; Myotonin-Protein Kinase; Neoplasm Invasiveness; Protein Kinase Inhibitors; Protein Multimerization; Protein-Tyrosine Kinases; Proteoglycans; Pyridines; rho-Associated Kinases; Thiophenes | 2011 |
The Rho/ROCK pathway for lysophosphatidic acid-induced proteolytic enzyme expression and ovarian cancer cell invasion.
Topics: Amides; Cell Line, Tumor; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Lysophospholipids; Neoplasm Invasiveness; NF-kappa B; Nitriles; Ovarian Neoplasms; Peptide Hydrolases; Pyridines; rho-Associated Kinases; Sulfones; Urokinase-Type Plasminogen Activator | 2012 |
Alphavbeta3 suppresses the RhoA-LIMK1 pathway in K1735 melanoma.
Topics: Actin Depolymerizing Factors; Amides; Animals; Blotting, Western; Cell Line, Tumor; Cell Membrane; Cell Nucleus; Cytoskeleton; Enzyme Activation; Enzyme Inhibitors; Genetic Vectors; Humans; Immunoprecipitation; Integrin alphaVbeta3; Lim Kinases; Melanoma; Mice; Microscopy, Fluorescence; Neoplasm Invasiveness; Phosphoprotein Phosphatases; Phosphorylation; Pyridines; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Signal Transduction; Transfection | 2012 |
Enhancement of migration and invasion of hepatoma cells via a Rho GTPase signaling pathway.
Topics: Amides; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Lysophospholipids; Neoplasm Invasiveness; Protein Serine-Threonine Kinases; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction | 2004 |
CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion.
Topics: Amides; Amiloride; Animals; Breast Neoplasms; Cathepsin B; Caveolin 1; Caveolins; Cell Line, Tumor; Endosomes; Enzyme Inhibitors; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Hydrogen-Ion Concentration; Immunoglobulin G; Intracellular Signaling Peptides and Proteins; Lysosomes; Membrane Microdomains; Membrane Proteins; Neoplasm Invasiveness; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases; RNA, Small Interfering; Sodium-Hydrogen Exchangers | 2004 |
Intrathecal administration of Y-27632, a specific rho-associated kinase inhibitor, for rat neoplastic meningitis.
Topics: Actins; Agar; Amides; Animals; Brain; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cells, Cultured; Chemotaxis; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Floxuridine; GTP-Binding Proteins; Injections, Spinal; Mammary Neoplasms, Animal; Meningeal Neoplasms; Meningitis; Mice; Microscopy, Fluorescence; Myosin Light Chains; Neoplasm Invasiveness; Neoplasm Transplantation; Neurons; Osmosis; Phosphorylation; Pyridines; Rats; Rats, Wistar; rho GTP-Binding Proteins; Signal Transduction; Time Factors | 2005 |
Inhibition of Rho-kinase affects astrocytoma morphology, motility, and invasion through activation of Rac1.
Topics: Actins; Amides; Astrocytoma; Cell Line, Tumor; Cell Movement; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Mutation; Neoplasm Invasiveness; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; rac1 GTP-Binding Protein; rho-Associated Kinases; Transfection | 2005 |
Mobility and invasiveness of metastatic esophageal cancer are potentiated by shear stress in a ROCK- and Ras-dependent manner.
Topics: Actins; Amides; Cell Adhesion; Cell Movement; Cells, Cultured; Cytoskeleton; Enzyme Inhibitors; Esophageal Neoplasms; Fibronectins; Humans; Integrin alphaVbeta3; Intracellular Signaling Peptides and Proteins; Neoplasm Invasiveness; Protein Serine-Threonine Kinases; Pyridines; ras Proteins; rho-Associated Kinases; Signal Transduction; Stress, Mechanical; Tissue Distribution; Tubulin | 2006 |
Rho-associated kinase inhibitor reduces tumor recurrence after liver transplantation in a rat hepatoma model.
Topics: Amides; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Immunosuppressive Agents; Intracellular Signaling Peptides and Proteins; Liver Neoplasms, Experimental; Liver Transplantation; Male; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred BUF; rho-Associated Kinases; Signal Transduction; Tacrolimus | 2007 |
Rho signaling inhibitor, Y-27632, inhibits invasiveness of metastastic hepatocellular carcinoma in a mouse model.
Topics: Actins; Amides; Animals; Apoptosis; Cytoskeleton; Enzyme Inhibitors; Female; Liver Neoplasms, Experimental; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Pyridines; ras Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; rhoC GTP-Binding Protein | 2007 |
An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.
Topics: Amides; Animals; Cell Adhesion; Cell Transformation, Neoplastic; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases; Transfection; Tumor Cells, Cultured | 1999 |
Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells.
Topics: Amides; Animals; Azepines; Cattle; Cell Division; Cells, Cultured; Chemotaxis; Endothelium, Vascular; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Transgenic; Myosin-Light-Chain Kinase; Myosin-Light-Chain Phosphatase; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Physiologic; Phosphoprotein Phosphatases; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Y-27632, an inhibitor of rho-associated protein kinase, suppresses tumor cell invasion via regulation of focal adhesion and focal adhesion kinase.
Topics: Actins; Amides; Animals; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Cytoskeletal Proteins; Drug Interactions; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Lysophospholipids; Neoplasm Invasiveness; Paxillin; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Rats; rho-Associated Kinases; Tumor Cells, Cultured; Tyrosine | 2000 |