Page last updated: 2024-09-03

y 27632 and Intraocular Pressure

y 27632 has been researched along with Intraocular Pressure in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (41.67)29.6817
2010's5 (41.67)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Chen, J; Fan, X; Fu, Y; Shao, C; Yu, F; Zhang, W1
Hikage, F; Ida, Y; Ohguro, H; Ota, C1
Bahler, CK; Fautsch, MP; Holman, BH; Roddy, GW; Roy Chowdhury, U; Sheikh-Hamad, D; Stamer, WD; Viker, KB; Winkler, NS1
Bahler, CK; Bertrand, JA; Dosa, PI; Fautsch, MP; Holman, BH; Millar, JC; Overby, DR; Rinkoski, TA; Roy Chowdhury, U; Sherwood, JM; Stoltz, KL1
Castermans, K; Defert, O; Hollanders, K; Leysen, D; Moons, L; Sijnave, D; Stalmans, I; Van Bergen, T; Van de Velde, S; Vandewalle, E1
Chlebowski, A; Freeburg, NF; John, SW; Kizhatil, K; Kokini, AD; Marchant, JK; Ryan, MM; Shaw, NN; Tolman, NG1
Bergkvist, M; Danias, J; Halman, JR; Papke, EL; Sharfstein, ST; Torrejon, KY; Xie, Y1
Abuin, A; Eberhart, DE; Gerhardt, B; Harrison, B; Mixon, T; Rice, DS; Whitlock, NA; Wilson, A; Yu, XQ1
Inatani, M; Katayama, K; Nemoto, S; Sakaki, H; Tanihara, H; Tokushige, H; Uehata, M1
Araie, M; Honjo, M; Kameda, T; Kawaji, T; Tanihara, H; Yoshimura, N1
Honda, Y; Honjo, M; Inatani, M; Kido, N; Narumiya, S; Sawamura, T; Tanihara, H; Yue, BY1
Azuma, M; Oka, T; Waki, M; Yoshida, Y1

Other Studies

12 other study(ies) available for y 27632 and Intraocular Pressure

ArticleYear
Y-27632 Promotes the Repair Effect of Umbilical Cord Blood-Derived Endothelial Progenitor Cells on Corneal Endothelial Wound Healing.
    Cornea, 2021, Feb-01, Volume: 40, Issue:2

    Topics: Amides; Animals; Blotting, Western; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cornea; Corneal Injuries; Culture Media, Conditioned; Disease Models, Animal; Endothelial Progenitor Cells; Endothelium, Corneal; Fetal Blood; Gene Expression Profiling; Gene Expression Regulation; Humans; Immunohistochemistry; Intraocular Pressure; Microscopy, Confocal; Oligonucleotide Array Sequence Analysis; Protein Kinase Inhibitors; Pyridines; Rabbits; Real-Time Polymerase Chain Reaction; rho-Associated Kinases; Stem Cell Transplantation; Transplantation, Heterologous; Wound Healing; Zonula Occludens-1 Protein

2021
ROCK inhibitors beneficially alter the spatial configuration of TGFβ2-treated 3D organoids from a human trabecular meshwork (HTM).
    Scientific reports, 2020, 11-20, Volume: 10, Issue:1

    Topics: Amides; Antihypertensive Agents; Cell Culture Techniques; Cell Line; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Isoquinolines; Microscopy, Electron, Scanning; Optic Nerve Diseases; Organoids; Pyridines; rho-Associated Kinases; Spheroids, Cellular; Sulfonamides; Trabecular Meshwork; Transforming Growth Factor beta2

2020
Stanniocalcin-1 Is an Ocular Hypotensive Agent and a Downstream Effector Molecule That Is Necessary for the Intraocular Pressure-Lowering Effects of Latanoprost.
    Investigative ophthalmology & visual science, 2017, 05-01, Volume: 58, Issue:5

    Topics: Aged; Aged, 80 and over; Amides; Animals; Anterior Eye Segment; Antihypertensive Agents; Blotting, Western; Cell Line; Gene Expression Regulation; Glycoproteins; Humans; Intraocular Pressure; Latanoprost; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron, Transmission; Middle Aged; Ocular Hypotension; Prostaglandins F, Synthetic; Pyridines; Real-Time Polymerase Chain Reaction; rho-Associated Kinases; RNA, Messenger; Signal Transduction; Tonometry, Ocular

2017
Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents.
    Investigative ophthalmology & visual science, 2017, 11-01, Volume: 58, Issue:13

    Topics: Amides; Animals; Anterior Eye Segment; Antihypertensive Agents; Aqueous Humor; Cromakalim; Drug Synergism; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Male; Mice; Mice, Inbred C57BL; Middle Aged; Ophthalmic Solutions; Prodrugs; Prostaglandins F, Synthetic; Pyridines; Rabbits; Sclera; Timolol; Tonometry, Ocular; Venous Pressure

2017
AMA0076, a novel, locally acting Rho kinase inhibitor, potently lowers intraocular pressure in New Zealand white rabbits with minimal hyperemia.
    Investigative ophthalmology & visual science, 2014, Feb-18, Volume: 55, Issue:2

    Topics: Actins; Amides; Animals; Antihypertensive Agents; Benzoates; Conjunctiva; Disease Models, Animal; Focal Adhesions; Hyperemia; Intraocular Pressure; Male; Ocular Hypertension; Protein Kinase Inhibitors; Pyridines; Rabbits; rho-Associated Kinases; Tonometry, Ocular; Trabecular Meshwork; Vinculin

2014
An In Vitro Perfusion System to Enhance Outflow Studies in Mouse Eyes.
    Investigative ophthalmology & visual science, 2016, Oct-01, Volume: 57, Issue:13

    Topics: Amides; Animals; Antihypertensive Agents; Aqueous Humor; Equipment Design; Intraocular Pressure; Mice; Mice, Inbred C57BL; Perfusion; Pyridines; Trabecular Meshwork

2016
TGFβ2-induced outflow alterations in a bioengineered trabecular meshwork are offset by a rho-associated kinase inhibitor.
    Scientific reports, 2016, 12-07, Volume: 6

    Topics: Actins; alpha-Crystallin B Chain; Amides; Animals; Cytoskeletal Proteins; Epoxy Compounds; Eye Proteins; Gene Expression Regulation; Glycoproteins; Humans; Intraocular Pressure; Models, Biological; Perfusion; Polymers; Pyridines; rho-Associated Kinases; Signal Transduction; Tissue Culture Techniques; Tissue Engineering; Tissue Scaffolds; Trabecular Meshwork; Transforming Growth Factor beta2

2016
Decreased intraocular pressure in mice following either pharmacological or genetic inhibition of ROCK.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2009, Volume: 25, Issue:3

    Topics: Acetazolamide; Administration, Topical; Adrenergic beta-Antagonists; Amides; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Intraocular Pressure; Latanoprost; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscarinic Agonists; Pilocarpine; Prostaglandins F, Synthetic; Pyridines; rho-Associated Kinases; Timolol

2009
Effects of topical administration of y-39983, a selective rho-associated protein kinase inhibitor, on ocular tissues in rabbits and monkeys.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:7

    Topics: Administration, Topical; Amides; Animals; Aqueous Humor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Intraocular Pressure; Macaca fascicularis; Male; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases

2007
Potential role of Rho-associated protein kinase inhibitor Y-27632 in glaucoma filtration surgery.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:12

    Topics: Actins; Amides; Animals; Cell Adhesion; Cell Differentiation; Cell Movement; Cell Proliferation; Cicatrix; Collagen Type I; Connective Tissue Cells; Cytoskeletal Proteins; Enzyme Inhibitors; Female; Fibroblasts; Fibronectins; Filtering Surgery; Glaucoma; Humans; Intraocular Pressure; Postoperative Complications; Pyridines; Rabbits; rho-Associated Kinases; Sclerostomy; Wound Healing

2007
Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility.
    Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:1

    Topics: Actins; Amides; Animals; Anterior Chamber; Aqueous Humor; Blotting, Western; Cells, Cultured; Ciliary Body; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Intracellular Signaling Peptides and Proteins; Intraocular Pressure; Muscle Contraction; Muscle, Smooth; Protein Serine-Threonine Kinases; Pupil; Pyridines; Rabbits; rho-Associated Kinases; Trabecular Meshwork; Vinculin

2001
Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase.
    Current eye research, 2001, Volume: 22, Issue:6

    Topics: Administration, Topical; Amides; Animals; Antihypertensive Agents; Carbachol; Ciliary Body; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Intraocular Pressure; Male; Muscle Contraction; Muscle, Smooth; Ophthalmic Solutions; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; Tonometry, Ocular

2001