Page last updated: 2024-09-03

y 27632 and Inflammation

y 27632 has been researched along with Inflammation in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (14.29)29.6817
2010's17 (80.95)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Anfossi, R; Carrillo, I; Castillo, C; Catalán, M; Clayton, NS; González-Herrera, F; Guzmán-Rivera, D; Kemmerling, U; Maya, JD; Olea-Azar, C; Quilaqueo, ME; Quintero-Pertuz, H; Ridley, AJ; Rivera-Meza, M; Vivar, R1
Athayde, RM; de Oliveira, VLS; Galvão, I; Gonçalves, WA; Perez, DA; Pinho, V; Reis, AC; Rezende, BM; Rezende, L; Sousa, LP; Teixeira, MM1
Chen, J; Chen, Y; Fan, Y; Gao, C; Li, W; Liu, D; Pan, S; Wang, H1
Cheung, CW; Chung, SK; Lee, UM; Wang, XM; Wong, SSC1
Hasan, Z; Hwaiz, R; Jeppsson, B; Lepsenyi, M; Palani, K; Rahman, M; Syk, I; Thorlacius, H; Zhang, S1
Chen, H; Cui, G; Hu, J; Hua, F; Jin, P; Jing, J; Liu, B; Ye, X; Zhao, H; Zhao, Q; Zhu, J; Zuo, T1
Ayaz, L; Canacankatan, N; Cuez, T; Gorur, A; Kacan, M; Kemal Buharalioglu, C; Korkmaz, B; Sahan Firat, S; Sari, AN; Sucu, N; Tamer Gumus, L; Tunctan, B; Unsal, D; Vezir, O1
Brown, KM; Ham, A; Kim, KY; Kim, M; Lee, HT1
Clemens, MG; Kwok, W1
McGee, DW; Perey, AC; Weishaar, IM1
Chai, Z; Feng, L; Li, YH; Liu, JC; Ma, CG; Xiao, BG; Xin, YL; Yu, JZ; Zhang, GX; Zhang, HZ1
Antunes, MA; dos Santos, AS; Leick, EA; Martins, Mde A; Pigati, PA; Possa, SS; Prado, CM; Righetti, RF; Rocco, PR; Rodrigues, AP; Romanholo, BS; Tibério, Ide F; Xisto, DG1
Cooper, DK; Hara, H; Lee, W; Long, C; Miyagawa, Y; Zhang, M1
Banerjee, S; McGee, DW1
Huang, W; Lai, W; Li, Y; Lou, T; Peng, H; Rao, J; Tang, H; Wang, C; Ye, Z1
Chen, SC; Chiou, SJ; Huang, SY; Liu, CC1
Ahn, JH; Hwang, JY; Jung, CH; Kim, YM; Lee, WJ; Lee, YL; Park, JY; Seol, SM1
Birukov, KG; Birukova, AA; Leff, A; Meliton, A; Tian, Y; Wu, T1
Dunn, G; Kelly, G; Martin, P; Redd, MJ; Way, M1
Bos, IS; Meurs, H; Schaafsma, D; Zaagsma, J; Zuidhof, AB1
Egashira, K; Inoue, S; Kaibuchi, K; Kataoka, C; Kitamoto, S; Koyanagi, M; Ni, W; Shimokawa, H; Takemoto, M; Takeshita, A; Usui, M1

Other Studies

21 other study(ies) available for y 27632 and Inflammation

ArticleYear
Statins change the cytokine profile in
    Frontiers in immunology, 2022, Volume: 13

    Topics: Animals; Atorvastatin; Cardiomyopathies; Chagas Disease; Cytokines; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Macrophages; Mice; NF-kappa B; rho-Associated Kinases; Trypanosoma cruzi; U937 Cells

2022
ROCK Inhibition Drives Resolution of Acute Inflammation by Enhancing Neutrophil Apoptosis.
    Cells, 2019, 08-23, Volume: 8, Issue:9

    Topics: Amides; Animals; Cell Survival; Disease Models, Animal; Gene Expression Regulation; Humans; I-kappa B Proteins; Inflammation; Lipopolysaccharides; Male; Mice; Neutrophils; Pyridines; rho-Associated Kinases

2019
Tetramethylpyrazine alleviates LPS-induced inflammatory injury in HUVECs by inhibiting Rho/ROCK pathway.
    Biochemical and biophysical research communications, 2019, 06-18, Volume: 514, Issue:1

    Topics: Acute Lung Injury; Amides; Apoptosis; Cell Survival; Cell-Derived Microparticles; Cytokines; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lipopolysaccharides; Platelet Endothelial Cell Adhesion Molecule-1; Protective Agents; Pyrazines; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases

2019
Role of DLC2 and RhoA/ROCK pathway in formalin induced inflammatory pain in mice.
    Neuroscience letters, 2019, 09-14, Volume: 709

    Topics: Amides; Animals; Formaldehyde; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle Relaxants, Central; Pain; Pain Measurement; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Tumor Suppressor Proteins

2019
Rho kinase regulates induction of T-cell immune dysfunction in abdominal sepsis.
    Infection and immunity, 2013, Volume: 81, Issue:7

    Topics: Amides; Animals; Apoptosis; Bacterial Load; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cecum; Cell Proliferation; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Forkhead Transcription Factors; HMGB1 Protein; Immunity, Cellular; Inflammation; Interleukin-17; Interleukin-2 Receptor alpha Subunit; Male; Mice; Mice, Inbred C57BL; Pyridines; rho-Associated Kinases; Sepsis; Spleen

2013
ROCK mediates the inflammatory response in thrombin induced microglia.
    Neuroscience letters, 2013, Oct-25, Volume: 554

    Topics: Amides; Animals; Antithrombins; Arginine; Cells, Cultured; Cerebral Cortex; Fluorescein; Fluorescent Dyes; Inflammation; Microglia; Microspheres; Nitric Oxide; Phagocytosis; Pipecolic Acids; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Sulfonamides; Thrombin; Tumor Necrosis Factor-alpha

2013
Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ injury in rats.
    European journal of pharmacology, 2014, Jan-15, Volume: 723

    Topics: Amides; Animals; Catalase; Glutathione; Inflammation; Kidney; Male; Malondialdehyde; MAP Kinase Kinase 1; MAP Kinase Signaling System; Muscle, Skeletal; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Peroxynitrous Acid; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; rho-Associated Kinases; rhoA GTP-Binding Protein; Superoxide Dismutase; Tyrosine

2014
The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Amides; Anesthetics, Inhalation; Animals; Antigens, CD; Cadherins; Cell Line, Transformed; Cell-Derived Microparticles; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Isoflurane; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Myosin-Light-Chain Phosphatase; Pyridines; rho-Associated Kinases; Signal Transduction

2014
Rho-kinase activation contributes to Lps-induced impairment of endothelial nitric oxide synthase activation by endothelin-1 in cultured hepatic sinusoidal endothelial cells.
    Shock (Augusta, Ga.), 2014, Volume: 42, Issue:6

    Topics: Actins; Amides; Animals; Caveolin 1; Cells, Cultured; Cofilin 1; Endothelial Cells; Endothelin-1; Enzyme Activation; Inflammation; Lipopolysaccharides; Liver; Male; Microcirculation; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Sepsis; Serine

2014
The effect of ROCK on TNF-α-induced CXCL8 secretion by intestinal epithelial cell lines is mediated through MKK4 and JNK signaling.
    Cellular immunology, 2015, Volume: 293, Issue:2

    Topics: Amides; Blotting, Western; Caco-2 Cells; Enzyme Inhibitors; Epithelial Cells; Humans; Inflammation; Interleukin-8; Intestines; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Phosphorylation; Pyridines; Real-Time Polymerase Chain Reaction; rho-Associated Kinases; RNA Interference; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha

2015
Protective effect of a novel Rho kinase inhibitor WAR-5 in experimental autoimmune encephalomyelitis by modulating inflammatory response and neurotrophic factors.
    Experimental and molecular pathology, 2015, Volume: 99, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Aminopyridines; Animals; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Immunosorbent Assay; Female; Immunoblotting; Immunoenzyme Techniques; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Microglia; Nerve Growth Factors; Piperidines; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; T-Lymphocytes, Regulatory

2015
Y-27632 is associated with corticosteroid-potentiated control of pulmonary remodeling and inflammation in guinea pigs with chronic allergic inflammation.
    BMC pulmonary medicine, 2015, Aug-12, Volume: 15

    Topics: Airway Remodeling; Amides; Animals; Asthma; Chronic Disease; Disease Models, Animal; Drug Synergism; Enzyme Inhibitors; Glucocorticoids; Guinea Pigs; Inflammation; Lung; Pyridines

2015
Effect of Rho-kinase Inhibitor, Y27632, on Porcine Corneal Endothelial Cell Culture, Inflammation and Immune Regulation.
    Ocular immunology and inflammation, 2016, Volume: 24, Issue:5

    Topics: Amides; Animals; Antibody Formation; Apoptosis; Cell Proliferation; Cells, Cultured; Cytokines; Endothelium, Corneal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Inflammation; Keratitis; Monocytes; Phosphorylation; Pyridines; Real-Time Polymerase Chain Reaction; rho-Associated Kinases; Swine; Transcription Factor RelA; Vascular Endothelial Growth Factor A; Wound Healing

2016
ROCK activity affects IL-1-induced signaling possibly through MKK4 and p38 MAPK in Caco-2 cells.
    In vitro cellular & developmental biology. Animal, 2016, Volume: 52, Issue:8

    Topics: Amides; Caco-2 Cells; Gene Expression Regulation; Humans; Inflammation; Interleukin-1; Interleukin-8; MAP Kinase Kinase 4; MAP Kinase Kinase 7; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; rho-Associated Kinases; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha

2016
The RhoA/ROCK Pathway Ameliorates Adhesion and Inflammatory Infiltration Induced by AGEs in Glomerular Endothelial Cells.
    Scientific reports, 2017, 01-05, Volume: 7

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cell Adhesion; Cell Movement; Cells, Cultured; Chemokine CCL2; Diabetic Nephropathies; Disease Models, Animal; Endothelial Cells; Glycation End Products, Advanced; Inflammation; Intercellular Adhesion Molecule-1; Kidney Glomerulus; Mice; Mice, Mutant Strains; Protein Kinase Inhibitors; Pyridines; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Small Interfering; Signal Transduction

2017
Vascular hyperpermeability in response to inflammatory mustard oil is mediated by Rho kinase in mice systemically exposed to arsenic.
    Microvascular research, 2011, Volume: 82, Issue:2

    Topics: Amides; Animals; Arsenic; Blood Pressure; Capillary Permeability; Carbon; Evans Blue; Inflammation; Male; Mice; Microcirculation; Mustard Plant; Plant Oils; Pyridines; rho-Associated Kinases

2011
The role of Rho/Rho-kinase pathway in the expression of ICAM-1 by linoleic acid in human aortic endothelial cells.
    Inflammation, 2012, Volume: 35, Issue:3

    Topics: Acute-Phase Proteins; Amides; Aorta; Cells, Cultured; DNA-Binding Proteins; Endothelial Cells; Endothelium, Vascular; Humans; Inflammation; Intercellular Adhesion Molecule-1; Linoleic Acid; Myosin-Light-Chain Phosphatase; NF-kappa B; Phosphorylation; Pyridines; rho-Associated Kinases; RNA Interference; RNA, Small Interfering; Signal Transduction

2012
Stimulation of Rho signaling by pathologic mechanical stretch is a "second hit" to Rho-independent lung injury induced by IL-6.
    American journal of physiology. Lung cellular and molecular physiology, 2012, May-01, Volume: 302, Issue:9

    Topics: Actin Cytoskeleton; Acute Lung Injury; Amides; Animals; Cells, Cultured; Cytoskeletal Proteins; Electric Impedance; Endothelial Cells; Humans; Inflammation; Interleukin-6; Intracellular Signaling Peptides and Proteins; Lung; Male; Mice; Mice, Inbred C57BL; Permeability; Proteolysis; Pulmonary Artery; Pyridines; Random Allocation; Respiration, Artificial; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Stress, Mechanical; Stress, Physiological

2012
Imaging macrophage chemotaxis in vivo: studies of microtubule function in zebrafish wound inflammation.
    Cell motility and the cytoskeleton, 2006, Volume: 63, Issue:7

    Topics: Amides; Animals; Chemotaxis; Embryo, Nonmammalian; Enzyme Inhibitors; Green Fluorescent Proteins; Inflammation; Intracellular Signaling Peptides and Proteins; Macrophages; Microscopy, Video; Microtubules; Nocodazole; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Wounds and Injuries; Yolk Sac; Zebrafish

2006
The inhaled Rho kinase inhibitor Y-27632 protects against allergen-induced acute bronchoconstriction, airway hyperresponsiveness, and inflammation.
    American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 295, Issue:1

    Topics: Acute Disease; Allergens; Amides; Animals; Asthma; Disease Models, Animal; Enzyme Inhibitors; Guinea Pigs; Inflammation; Male; Neutrophils; Pyridines; rho-Associated Kinases; Time Factors

2008
Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:2

    Topics: Actins; Amides; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Chemokine CCL2; Coronary Vessels; Enzyme Inhibitors; Hydralazine; Immunohistochemistry; Inflammation; Intracellular Signaling Peptides and Proteins; Kidney Glomerulus; Muscle, Smooth; Myosins; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred WKY; rho-Associated Kinases; RNA, Messenger; Superoxide Dismutase; Tetrazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1

2002