y 27632 has been researched along with Huntington Disease in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, M; Beaumont, V; Cachope, R; Chauhan, A; Dominguez, C; Gallati, C; Haughan, AF; Kempf, G; Ladduwahetty, T; Lee, MR; Luckhurst, CA; Maillard, MC; Matthews, K; McAllister, G; Mitchell, P; Munoz-Sanjuan, I; Patel, H; Rose, M; Saville-Stones, E; Steinbacher, S; Stott, AJ; Thatcher, E; Tierney, J; Todd, D; Urbonas, L | 1 |
| Benicchi, T; Caricasole, A; Diamanti, D; Fecke, W; Federico, C; Heitz, F; La Rosa, S; Lazzeroni, G; Magnoni, L; Massai, L; Porcari, V; Rossini, L | 1 |
| Diamond, MI; Huang, Y; Li, M; Lin, E; Ma, AA | 1 |
| Agrawal, N; Apostol, BL; Bodai, L; Chang, LW; Chiang, AS; Marsh, JL; Pallos, J; Slepko, N; Thompson, LM | 1 |
| Diamond, MI; Shao, J; Welch, WJ | 1 |
5 other study(ies) available for y 27632 and Huntington Disease
| Article | Year |
|---|---|
Identification of a Potent, Selective, and Brain-Penetrant Rho Kinase Inhibitor and its Activity in a Mouse Model of Huntington's Disease.
Topics: Animals; Brain; Disease Models, Animal; Huntingtin Protein; Huntington Disease; Mice; Protein Kinase Inhibitors; rho-Associated Kinases | 2022 |
A phenotypic screening assay for modulators of huntingtin-induced transcriptional dysregulation.
Topics: Amides; Biological Assay; Cell Line, Tumor; CREB-Binding Protein; Gene Expression Regulation; Genes, Reporter; Humans; Huntingtin Protein; Huntington Disease; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Peptides; Protein Binding; Pyridines; Response Elements; rho-Associated Kinases; Signal Transduction; Small Molecule Libraries; Transcription, Genetic | 2013 |
Y-27632 improves rotarod performance and reduces huntingtin levels in R6/2 mice.
Topics: Amides; Animals; Brain; Cell Count; Disease Models, Animal; Dyskinesias; Enzyme Inhibitors; Female; Half-Life; Huntingtin Protein; Huntington Disease; Longevity; Mice; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Pyridines; Random Allocation; rho-Associated Kinases; Time Factors | 2009 |
Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila.
Topics: Amides; Animals; Benzoquinones; Disease Models, Animal; Drosophila; Drug Therapy, Combination; Female; Huntington Disease; Hydroxamic Acids; Lactams, Macrocyclic; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Pyridines; Quinones; Vorinostat | 2005 |
ROCK and PRK-2 mediate the inhibitory effect of Y-27632 on polyglutamine aggregation.
Topics: Amides; Animals; Cell Line; Drosophila; Humans; Huntingtin Protein; Huntington Disease; Muscle Relaxants, Central; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; RNA Interference | 2008 |