Compounds > y 27632
Page last updated: 2024-09-03

y 27632 and Erectile Dysfunction

y 27632 has been researched along with Erectile Dysfunction in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (81.25)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Albersen, M; Bivalacqua, TJ; Bollen, I; Brône, B; De Ridder, DJ; Falter, M; Linsen, L; Sandner, P; Tinel, H; Uvin, P; Van der Aa, F; Van Renterghem, K; Weyne, E1
Thoma, C1
Dorrance, AM; Leite, R; Linder, AE; Mills, TM; Webb, RC1
Albersen, M; Bivalacqua, TJ; Burnett, AL; Gratzke, C; Hannan, JL; Hedlund, P; Kutlu, O; Lysiak, JJ; Stief, CG1
Holmes, A; Johnson, JA; Prikosh, A; Wingard, CJ1
Dai, YT; Lewis, RW; Mills, TM; Webb, RC1
Jin, L; Linder, AE; Mills, TM; Webb, RC1
Andersson, KE1
Hopps, CV; Mulhall, JP1
Bivalacqua, TJ; Cellek, S; Champion, HC; Chitaley, K; Hellstrom, WJ; Kadowitz, PJ; Lewis, RL; Mills, TM; Usta, MF; Webb, RC1
Bivalacqua, TJ; Burnett, AL; Champion, HC; Jin, L; Lagoda, GA; Liu, T1
Aslan, G; Demir, O; Esen, AA; Gidener, S; Murat, N1
Ambrosini, S; Filippi, S; Forti, G; Luconi, M; Maggi, M; Mancina, R; Morelli, A; Mungai, S; Vannelli, GB; Vignozzi, L; Zhang, XH1
Gao, BH; Liu, YQ; Meng, FW; Shi, BK; Xu, ZS; Zhao, ST1
Gur, S; Hellstrom, WJ; Kadowitz, PJ; Trost, L1
Weitzman, J1

Reviews

3 review(s) available for y 27632 and Erectile Dysfunction

ArticleYear
Inhibition of the tonic contraction in the treatment of erectile dysfunction.
    Expert opinion on therapeutic targets, 2003, Volume: 7, Issue:2

    Topics: Adrenergic Agonists; Adult; Aged; Aging; Amides; Angiotensin II; Calcium Signaling; Cyclic AMP; Endothelin-1; Erectile Dysfunction; Forecasting; Humans; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Penis; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasoactive Intestinal Peptide

2003
Erectile physiological and pathophysiological pathways involved in erectile dysfunction.
    The Journal of urology, 2003, Volume: 170, Issue:2 Pt 2

    Topics: Amides; Animals; Diabetes Mellitus; Endothelin-1; Erectile Dysfunction; Humans; Hypothalamus; Male; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Nitric Oxide; Norepinephrine; Penile Erection; Phosphorylation; Pyridines; Receptors, Endothelin; rho GTP-Binding Proteins

2003
Novel agents for sexual dysfunction.
    BJU international, 2003, Volume: 92, Issue:6

    Topics: Administration, Topical; Adrenergic alpha-Antagonists; Alprostadil; Amides; Calcium Channels; Dopamine Agonists; Drug Therapy, Combination; Endothelial Growth Factors; Enzyme Inhibitors; Erectile Dysfunction; Humans; Intercellular Signaling Peptides and Proteins; Lymphokines; Male; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Pyridines; Receptors, Corticotropin; Receptors, Melanocortin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003

Other Studies

13 other study(ies) available for y 27632 and Erectile Dysfunction

ArticleYear
Additive effects of the Rho kinase inhibitor Y-27632 and vardenafil on relaxation of the corpus cavernosum tissue of patients with erectile dysfunction and clinical phosphodiesterase type 5 inhibitor failure.
    BJU international, 2017, Volume: 119, Issue:2

    Topics: Amides; Drug Synergism; Enzyme Inhibitors; Erectile Dysfunction; Humans; Male; Middle Aged; Penis; Phosphodiesterase 5 Inhibitors; Pyridines; rho-Associated Kinases; Treatment Failure; Vardenafil Dihydrochloride

2017
Erectile dysfunction: Too much ROCK - erection block.
    Nature reviews. Urology, 2017, Volume: 14, Issue:1

    Topics: Amides; Cyclic Nucleotide Phosphodiesterases, Type 5; Erectile Dysfunction; Humans; Male; Penile Erection; Phosphodiesterase 5 Inhibitors; Pyridines; rho-Associated Kinases; Vardenafil Dihydrochloride

2017
Erectile function in two-kidney, one-clip hypertensive rats is maintained by a potential increase in nitric oxide production.
    The journal of sexual medicine, 2009, Volume: 6 Suppl 3

    Topics: Amides; Animals; Antihypertensive Agents; Erectile Dysfunction; Ganglion Cysts; Hypertension; Indomethacin; Kidney; Male; Nitric Oxide; Nitroprusside; Penis; Phenylephrine; Pressure; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases

2009
Inhibition of Rho-kinase improves erectile function, increases nitric oxide signaling and decreases penile apoptosis in a rat model of cavernous nerve injury.
    The Journal of urology, 2013, Volume: 189, Issue:3

    Topics: Amides; Animals; Apoptosis; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Erectile Dysfunction; Male; Nitric Oxide; Penile Erection; Penis; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Up-Regulation

2013
Improved erectile function after Rho-kinase inhibition in a rat castrate model of erectile dysfunction.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:6

    Topics: Amides; Animals; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Erectile Dysfunction; Gene Expression Regulation; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Muscle, Smooth; Orchiectomy; Penis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Testosterone; Time Factors

2003
[Inhibition of tonic contraction of smooth muscle: a new approach to achieve erection dysfunction].
    Zhonghua nan ke xue = National journal of andrology, 2002, Volume: 8, Issue:6

    Topics: Amides; Animals; Disease Models, Animal; Erectile Dysfunction; Humans; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth, Vascular; Penile Erection; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein

2002
RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: a mechanism for diabetes-associated erectile dysfunction.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Jun-15, Volume: 101, Issue:24

    Topics: Adenoviridae; Amides; Animals; Blood Glucose; Body Weight; Cyclic GMP; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Erectile Dysfunction; Gene Expression; Intracellular Signaling Peptides and Proteins; Male; Muscle Relaxants, Central; Myosin-Light-Chain Phosphatase; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Penis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Transfection

2004
Elevated RhoA/Rho-kinase activity in the aged rat penis: mechanism for age-associated erectile dysfunction.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:3

    Topics: Aging; Amides; Amino Acid Substitution; Animals; Dependovirus; Erectile Dysfunction; Genetic Therapy; Genetic Vectors; Intracellular Signaling Peptides and Proteins; Isoenzymes; Male; Muscle Contraction; Muscle, Smooth, Vascular; Mutation, Missense; Myosin-Light-Chain Phosphatase; Penis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred F344; Recombinant Fusion Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasodilation

2006
Effect of doxazosin with and without rho-kinase inhibitor on human corpus cavernosum smooth muscle in the presence of bladder outlet obstruction.
    The Journal of urology, 2006, Volume: 175, Issue:6

    Topics: Adrenergic alpha-Antagonists; Aged; Amides; Dose-Response Relationship, Drug; Doxazosin; Erectile Dysfunction; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Penis; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Urinary Bladder Neck Obstruction

2006
Testosterone regulates RhoA/Rho-kinase signaling in two distinct animal models of chemical diabetes.
    The journal of sexual medicine, 2007, Volume: 4, Issue:3

    Topics: Alloxan; Amides; Animals; Blotting, Western; Diabetes Mellitus, Experimental; Disease Models, Animal; Erectile Dysfunction; Hypogonadism; Intracellular Signaling Peptides and Proteins; Male; Penis; Protein Serine-Threonine Kinases; Pyridines; Rabbits; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; Streptozocin; Testosterone; Up-Regulation

2007
Y-27632 improves the erectile dysfunction with ageing in SD rats through adjusting the imbalance between nNo and the Rho-kinase pathways.
    Andrologia, 2007, Volume: 39, Issue:4

    Topics: Aging; Amides; Animals; Erectile Dysfunction; Intracellular Signaling Peptides and Proteins; Male; Models, Molecular; Nitric Oxide Synthase Type I; Penile Erection; Penis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases

2007
Optimizing nitric oxide production by time dependent L-arginine administration in isolated human corpus cavernosum.
    The Journal of urology, 2007, Volume: 178, Issue:4 Pt 1

    Topics: Aged; Amides; Arginine; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Erectile Dysfunction; Humans; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Penile Erection; Penis; Piperazines; Purines; Pyridines; Sildenafil Citrate; Sulfones

2007
Alternatives to Viagra.
    Trends in molecular medicine, 2001, Volume: 7, Issue:3

    Topics: Amides; Animals; Enzyme Inhibitors; Erectile Dysfunction; Intracellular Signaling Peptides and Proteins; Male; Nitric Oxide; Penile Erection; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases

2001