Page last updated: 2024-09-03

y 27632 and Cardiomegaly

y 27632 has been researched along with Cardiomegaly in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (75.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, J; Chen, XM; Hou, JW; Li, G; Li, W; Li, YG; Wang, H; Wang, Q; Wang, YP; Wei, SS; Xu, WP; Zhou, Q1
Chang, L; Guo, B; Jin, X; Li, Y; Liu, S; Miao, C; Wang, Y; Yan, J; Yang, R; Zhang, H1
Hunter, JC; Javadov, S; Karmazyn, M; Kilić, A; Rajapurohitam, V; Zeidan, A1
Bauer, NR; Fagan, KA; Gebb, SA; Ivy, DD; McMurtry, IF; Morris, KG; Oka, M1
Adachi, S; Isobe, M; Ito, H; Kitajima, S; Maejima, Y; Morikawa-Futamatsu, K; Suzuki, J; Tamamori-Adachi, M1
Jiang, WP; Jing, HM; Liu, ZH; Pan, M; Yang, XJ; Zhu, JH1
Ahuja, P; Ehler, E; Pedrazzini, T; Perriard, E; Perriard, JC; Satoh, S1
Kass, DA; McKinsey, TA1

Reviews

1 review(s) available for y 27632 and Cardiomegaly

ArticleYear
Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface.
    Nature reviews. Drug discovery, 2007, Volume: 6, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cardiomegaly; Cardiovascular Agents; Humans; Models, Biological; Molecular Structure; Pyridines; Receptors, Cell Surface; Signal Transduction

2007

Other Studies

7 other study(ies) available for y 27632 and Cardiomegaly

ArticleYear
Crucial Role of ROCK2-Mediated Phosphorylation and Upregulation of FHOD3 in the Pathogenesis of Angiotensin II-Induced Cardiac Hypertrophy.
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 69, Issue:6

    Topics: Amides; Analysis of Variance; Angiotensin II; Animals; Blotting, Western; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Formins; Male; Microfilament Proteins; Myocytes, Cardiac; Phosphorylation; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; rho-Associated Kinases; Signal Transduction; Up-Regulation

2017
Angiotensin II increases secreted frizzled-related protein 5 (sFRP5) expression through AT1 receptor/Rho/ROCK1/JNK signaling in cardiomyocytes.
    Molecular and cellular biochemistry, 2015, Volume: 408, Issue:1-2

    Topics: Adipokines; Amides; Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Eye Proteins; Myocytes, Cardiac; Pyridines; Rats; Tumor Necrosis Factor-alpha

2015
Nitric oxide inhibits endothelin-1-induced neonatal cardiomyocyte hypertrophy via a RhoA-ROCK-dependent pathway.
    Journal of molecular and cellular cardiology, 2009, Volume: 47, Issue:6

    Topics: Actins; Amides; Animals; Animals, Newborn; Cardiomegaly; Cofilin 2; Cyclic GMP; Endothelin-1; Isoenzymes; Models, Biological; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Protein Transport; Pyridines; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Time Factors; Transcription Factors

2009
Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 287, Issue:4

    Topics: Amides; Animals; Cardiomegaly; Enzyme Inhibitors; Hematocrit; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Lung; Male; Mice; Mice, Inbred C57BL; Perfusion; Protein Serine-Threonine Kinases; Pulmonary Circulation; Pyridines; rho-Associated Kinases; Vasoconstriction; Ventricular Dysfunction, Right; Ventricular Function, Right

2004
HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1.
    Life sciences, 2006, Aug-29, Volume: 79, Issue:14

    Topics: Adenoviridae Infections; Amides; Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Cyclin D1; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoblotting; Indoles; Intracellular Signaling Peptides and Proteins; Leucine; Male; Mevalonic Acid; Myocardium; Myocytes, Cardiac; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; RNA, Messenger

2006
Rho-kinase inhibitor may exert a role in preventing cardiac hypertrophy, independent of antihypertensive effects.
    Medical hypotheses, 2007, Volume: 68, Issue:1

    Topics: Amides; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Models, Cardiovascular; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases

2007
Re-expression of proteins involved in cytokinesis during cardiac hypertrophy.
    Experimental cell research, 2007, Apr-01, Volume: 313, Issue:6

    Topics: Actomyosin; Amides; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; Calpain; Cardiomegaly; Cell Nucleus Division; Cullin Proteins; Cytokinesis; Heart; Hypertension; Intracellular Signaling Peptides and Proteins; Mice; Myocytes, Cardiac; Myofibrils; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred Dahl; rho GTP-Binding Proteins; rho-Associated Kinases; Up-Regulation

2007