Compounds > y 27632
Page last updated: 2024-09-03

y 27632 and Bronchial Hyperreactivity

y 27632 has been researched along with Bronchial Hyperreactivity in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (81.82)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aimbire, F; Castro-Faria-Neto, HC; de Oliveira, AP; Marcondes, P; Silva, M; Silva, VR; Vieira, RP; Villaverde, AB1
Chiba, Y; Hanazaki, M; Misawa, M; Sakai, H; Sato, S1
Aimbire, F; Albertini, R; Bjordal, JM; de Lima, FM; Santos, FV1
Goldie, RG; Henry, PJ; Mann, TS1
Chiba, Y; Misawa, M; Sakai, H; Yu, Y1
Janssen, LJ; Liu, C; Tazzeo, T1
Bos, IS; Meurs, H; Schaafsma, D; Zaagsma, J; Zuidhof, AB1
Honjo, H; Ito, S; Kamiya, K; Kondo, M; Kume, H; Makino, Y; Oguma, T; Shimokata, K1
Ahrens, B; Hamelmann, E; Hippenstiel, S; Kube, SM; Rosseau, S; Schmeck, B; Schütte, H; Suttorp, N; Witzenrath, M1
Chiba, Y; Misawa, M; Sakai, H1
Fang, YI; Hashimoto, T; Momose, K; Nakano, Y; Ohata, H; Yamashita, M1

Other Studies

11 other study(ies) available for y 27632 and Bronchial Hyperreactivity

ArticleYear
Low-level laser therapy inhibits bronchoconstriction, Th2 inflammation and airway remodeling in allergic asthma.
    Respiratory physiology & neurobiology, 2014, Apr-01, Volume: 194

    Topics: Airway Remodeling; Amides; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Cytokines; Enzyme Inhibitors; Hypersensitivity; Low-Level Light Therapy; Lung; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth; Ovalbumin; Pneumonia; Pyridines; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; STAT6 Transcription Factor

2014
Inhibition of geranylgeranyltransferase inhibits bronchial smooth muscle hyperresponsiveness in mice.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 297, Issue:5

    Topics: Alkyl and Aryl Transferases; Amides; Animals; Bronchial Hyperreactivity; Enzyme Inhibitors; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Muscle Relaxation; Muscle, Smooth; Prenylation; Pyridines; rhoA GTP-Binding Protein

2009
Low-level laser therapy (LLLT) attenuates RhoA mRNA expression in the rat bronchi smooth muscle exposed to tumor necrosis factor-alpha.
    Lasers in medical science, 2010, Volume: 25, Issue:5

    Topics: Amides; Animals; Bronchi; Bronchial Hyperreactivity; Calcium Signaling; Gene Expression; In Vitro Techniques; Low-Level Light Therapy; Male; Muscle, Smooth; Pyridines; Rats; Rats, Wistar; rhoA GTP-Binding Protein; RNA, Messenger; Tumor Necrosis Factor-alpha

2010
A rho kinase inhibitor, Y-27632 inhibits pulmonary eosinophilia, bronchoconstriction and airways hyperresponsiveness in allergic mice.
    Pulmonary pharmacology & therapeutics, 2005, Volume: 18, Issue:1

    Topics: Administration, Intranasal; Aluminum Hydroxide; Amides; Animals; Australia; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Bronchoconstriction; Disease Models, Animal; Female; Hypersensitivity; Injections, Intraperitoneal; Intracellular Signaling Peptides and Proteins; Lung; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Protein Serine-Threonine Kinases; Pulmonary Eosinophilia; Pyridines; rho-Associated Kinases

2005
Effects of repeated antigen exposure on endothelin-1-induced bronchial smooth muscle contraction and activation of RhoA in sensitized rats.
    Journal of biochemistry, 2005, Volume: 137, Issue:6

    Topics: Amides; Animals; Antigens; Bronchi; Bronchial Hyperreactivity; Calcium; Dose-Response Relationship, Drug; Endothelin-1; Male; Muscle Contraction; Muscle, Smooth; Pyridines; Rats; Rats, Wistar; rhoA GTP-Binding Protein; Time Factors

2005
Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca2+ handling and Rho/ROCK signaling.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 291, Issue:6

    Topics: Amides; Animals; Bronchial Hyperreactivity; Calcium; Carbachol; Cattle; Dinoprostone; Enzyme Inhibitors; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoprostanes; Muscle, Smooth; Protein Serine-Threonine Kinases; Pyridines; Respiratory System; rho-Associated Kinases; Signal Transduction; Trachea

2006
Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction.
    Respiratory research, 2006, Sep-26, Volume: 7

    Topics: Administration, Inhalation; Amides; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Enzyme Inhibitors; Guinea Pigs; Intracellular Signaling Peptides and Proteins; Male; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Treatment Outcome

2006
Roles of P2X receptors and Ca2+ sensitization in extracellular adenosine triphosphate-induced hyperresponsiveness in airway smooth muscle.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2007, Volume: 37, Issue:6

    Topics: Adenosine Triphosphate; Amides; Animals; Bronchi; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Calcium; Calcium Signaling; Cells, Cultured; Drug Synergism; Enzyme Inhibitors; Guinea Pigs; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Male; Methacholine Chloride; Myocytes, Smooth Muscle; Organ Culture Techniques; Phosphoprotein Phosphatases; Protein Serine-Threonine Kinases; Pulmonary Disease, Chronic Obstructive; Purinergic P2 Receptor Agonists; Pyridines; Receptors, Purinergic P2; Receptors, Purinergic P2X; Respiratory Mucosa; rho-Associated Kinases; src-Family Kinases; Time Factors

2007
Rho-kinase and contractile apparatus proteins in murine airway hyperresponsiveness.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2008, Volume: 60, Issue:1

    Topics: Amides; Animals; Asthma; Blotting, Western; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Enzyme Inhibitors; Female; Lung; Mice; Mice, Inbred BALB C; Muscle, Smooth; Myosin Light Chains; Myosin-Light-Chain Kinase; Ovalbumin; Perfusion; Phosphorylation; Pyridines; rho-Associated Kinases

2008
Augmented acetylcholine-induced translocation of RhoA in bronchial smooth muscle from antigen-induced airway hyperresponsive rats.
    British journal of pharmacology, 2001, Volume: 133, Issue:6

    Topics: Acetylcholine; Amides; Animals; Antigens; Biological Transport; Bronchi; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Enzyme Inhibitors; Muscle Contraction; Muscle, Smooth; Papaverine; Pyridines; Rats; Rats, Wistar; rhoA GTP-Binding Protein; Time Factors; Vasodilator Agents

2001
Role of Rho-associated protein kinase and histamine in lysophosphatidic acid-induced airway hyperresponsiveness in guinea pigs.
    Japanese journal of pharmacology, 2002, Volume: 88, Issue:3

    Topics: Acetylcholine; Amides; Animals; Bronchial Hyperreactivity; Enzyme Inhibitors; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine Release; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Ketotifen; Lung; Lysophospholipids; Male; Muscle Contraction; Muscle, Smooth; Protein Serine-Threonine Kinases; Pyridines; Pyrilamine; rho-Associated Kinases; Structure-Activity Relationship

2002