y 27632 has been researched along with Blood Pressure, High in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.50) | 18.2507 |
| 2000's | 31 (77.50) | 29.6817 |
| 2010's | 7 (17.50) | 24.3611 |
| 2020's | 1 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Inui, J; Ishizaki, T; Kawahara, T; Maekawa, M; Morishita, T; Narumiya, S; Ono, T; Satoh, H; Tamakawa, H; Uehata, M; Yamagami, K | 1 |
| Beasley, JR; Belanger, L; Black, D; Chan, JH; Dunn, D; Ho, KK; Hu, B; Klon, A; Kultgen, SG; Ohlmeyer, M; Parlato, SM; Pham, Q; Ray, PC; Rong, Y; Roughton, AL; Walker, TL; Webb, M; Wright, J; Xu, K; Xu, Y; Zhang, L | 1 |
| Cho, S; Kim, HJ; Kim, SJ; Oh, SB | 1 |
| Costa, KD; Lee, JJ; Ma, B; Qiu, H; Stoll, S; Zhou, N | 1 |
| Hu, K; Liu, P; Tang, S; Zhang, HM; Zhou, XF | 1 |
| Ark, M; Aypar, E; Demirtaş, A; Gözübüyük, G; Ozdemir, A; Şahan, G; Turan, NN | 1 |
| Chen, HS; Jiang, FY; Li, RS; Li, WJ; Tu, Q; Wang, Y; Yin, RX | 1 |
| Hirooka, Y; Ito, K; Kimura, Y; Sagara, Y; Sunagawa, K | 2 |
| Chan, CK; Mak, JC; Man, RY; Vanhoutte, PM | 1 |
| Dorrance, AM; Leite, R; Linder, AE; Mills, TM; Webb, RC | 1 |
| Eto, M; Freitas, MR; Kirkbride, JA; Sassard, J; Schott, C; Stoclet, JC | 1 |
| Denniss, SG; Jeffery, AJ; Rush, JW | 1 |
| Guan, YY; Li, SY; Ma, MM; Wang, M | 1 |
| Chatterjee, P; Chiasson, VL; Kopriva, SE; Mitchell, BM; Nguyen, H; Young, KJ | 1 |
| Begaye, M; Carter, RW; Kanagy, NL | 1 |
| Hartshorne, DJ; Isaka, N; Ito, M; Kureishi, Y; Moriki, N; Nakano, T; Okamoto, R; Onishi, K; Seko, T | 1 |
| Kadokami, T; Koyanagi, M; Makino, N; Satoh, S; Sugano, M; Ueda, Y; Yoshikawa, Y | 1 |
| Asano, M; Nomura, Y | 1 |
| Hirooka, Y; Ito, K; Kaibuchi, K; Kishi, T; Sakai, K; Shimokawa, H; Takeshita, A | 1 |
| Hirooka, Y; Ito, K; Kaibuchi, K; Kimura, Y; Kishi, T; Shimokawa, H; Takeshita, A | 1 |
| Loberg, RD; Northcott, CA; Watts, SW; Wehrwein, EA | 1 |
| Bernie, J; Rajasekaran, M; Stein, P; White, S; Wilkes, N | 1 |
| Amano, M; Kaibuchi, K; Kawabata, S; Nakayama, M; Takefuji, M | 1 |
| Kobayashi, N; Matsuoka, H; Mita, S; Nakano, S; Yoshida, K | 1 |
| E Albo, M; Kuntz, S; Rajasekaran, M; Wilkes, N | 1 |
| Bae, YM; Cho, S; Choi, WH; Kim, B; Kim, J; Lee, CH; Lee, CK; Lee, YR | 1 |
| Alvarez de Sotomayor, M; Herrera, MD; Marhuenda, E; Márquez-Martín, A; Pérez-Guerrero, C | 1 |
| Jarajapu, YP; Knot, HJ | 1 |
| Ahn, DS; Cho, YE; Choi, SK; Kim, YH; Lee, YH; Morgan, KG; Ryu, SK | 1 |
| Hilgers, RH; Imig, JD; Jin, L; Webb, RC; Yin, J; Ying, Z; Zhao, X | 1 |
| Ahuja, P; Ehler, E; Pedrazzini, T; Perriard, E; Perriard, JC; Satoh, S | 1 |
| Ahn, DS; Cho, YE; Choi, SK; Kim, YH; Lee, YH; Morgan, KG; Shin, HM | 1 |
| Hilgers, RH; Todd, J; Webb, RC | 1 |
| Chrissobolis, S; Sobey, CG | 1 |
| Webb, RC; Weber, DS | 1 |
| Chitaley, K; Dorrance, AM; Mills, TM; Webb, RC | 1 |
| Fujishima, M; Ibayashi, S; Kitayama, J; Kitazono, T; Ooboshi, H; Takada, J | 1 |
| Honda, T; Kobayashi, N; Kobayashi, T; Matsuoka, H; Mita, S; Nakano, S; Tsubokou, Y | 1 |
| Ago, T; Fujishima, M; Ibayashi, S; Kamouchi, M; Kitazono, T; Ooboshi, H; Santa, N | 1 |
1 review(s) available for y 27632 and Blood Pressure, High
| Article | Year |
|---|---|
[Involvement of small GTPase Rho and Rho-kinase in the pathogenesis of hypertension and hypertensive target organ damage].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Angina Pectoris; Animals; Arteriosclerosis; Calcium; Enzyme Inhibitors; Humans; Hypertension; Intracellular Signaling Peptides and Proteins; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Kinase; Protein Serine-Threonine Kinases; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases | 2004 |
39 other study(ies) available for y 27632 and Blood Pressure, High
| Article | Year |
|---|---|
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension.
Topics: Amides; Animals; Antihypertensive Agents; Calcium; Cell Adhesion; COS Cells; Enzyme Inhibitors; Guinea Pigs; Humans; Hypertension; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Pyridines; Rabbits; Radioligand Assay; Rats; Rats, Wistar; Recombinant Proteins; rho-Associated Kinases; Swine | 1997 |
Triazine and pyrimidine based ROCK inhibitors with efficacy in spontaneous hypertensive rat model.
Topics: Animals; Antihypertensive Agents; Binding Sites; Computer Simulation; Disease Models, Animal; Hypertension; Protein Kinase Inhibitors; Pyrimidines; Rats; rho-Associated Kinases; Structure-Activity Relationship; Triazines | 2009 |
T18/S19 diphosphorylation of myosin regulatory light chain impairs pulmonary artery relaxation in monocrotaline-induced pulmonary hypertensive rats.
Topics: Animals; Hypertension; Monocrotaline; Myosin Light Chains; Pulmonary Artery; Rats; rho-Associated Kinases | 2023 |
Rho Kinase Regulates Aortic Vascular Smooth Muscle Cell Stiffness Via Actin/SRF/Myocardin in Hypertension.
Topics: Actins; Amides; Animals; Aorta, Thoracic; Blood Pressure; Cytoskeletal Proteins; Echocardiography; Hypertension; Male; Microscopy, Atomic Force; Muscle Proteins; Muscle, Smooth, Vascular; Myosin Heavy Chains; Nipecotic Acids; Nuclear Proteins; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; Serum Response Factor; Trans-Activators; Ultrasonography; Up-Regulation; Vascular Stiffness | 2017 |
Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia.
Topics: Amides; Animals; Apoptosis; Blood Pressure; Carotid Body; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Hypertension; Hypoxia; Male; NADPH Oxidases; Neuronal Plasticity; Onium Compounds; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; rho-Associated Kinases; Signal Transduction | 2019 |
Chronic ouabain treatment induces Rho kinase activation.
Topics: Amides; Animals; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Male; Myosin-Light-Chain Phosphatase; Ouabain; Phenylephrine; Potassium Chloride; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases | 2015 |
TMEM16A contributes to angiotensin II-induced cerebral vasoconstriction via the RhoA/ROCK signaling pathway.
Topics: Amides; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anoctamin-1; Basilar Artery; Cells, Cultured; Chloride Channels; Disease Models, Animal; Evoked Potentials; Hypertension; Male; Muscle, Smooth, Vascular; Protein Phosphatase 1; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Vasoconstriction | 2016 |
Activation of Rho-kinase in the brainstem enhances sympathetic drive in mice with heart failure.
Topics: Amides; Animals; Autonomic Pathways; Blood Vessels; Brain Stem; Cytoskeletal Proteins; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred ICR; Myocardial Infarction; Norepinephrine; Organ Size; Pyridines; rho-Associated Kinases; Sympathetic Nervous System; Up-Regulation; Vasoconstriction | 2008 |
Rho kinase inhibitors prevent endothelium-dependent contractions in the rat aorta.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Antihypertensive Agents; Aorta, Thoracic; Blotting, Western; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; In Vitro Techniques; Isometric Contraction; Male; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; Species Specificity; Vasoconstriction | 2009 |
Erectile function in two-kidney, one-clip hypertensive rats is maintained by a potential increase in nitric oxide production.
Topics: Amides; Animals; Antihypertensive Agents; Erectile Dysfunction; Ganglion Cysts; Hypertension; Indomethacin; Kidney; Male; Nitric Oxide; Nitroprusside; Penis; Phenylephrine; Pressure; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases | 2009 |
Y27632, a Rho-activated kinase inhibitor, normalizes dysregulation in alpha1-adrenergic receptor-induced contraction of Lyon hypertensive rat artery smooth muscle.
Topics: Amides; Animals; Calcium; Calcium Chloride; Disease Models, Animal; Hypertension; Male; Mesenteric Arteries; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Protein Phosphatase 1; Pyridines; Rats; Receptors, Adrenergic, alpha-1; rho-Associated Kinases; Signal Transduction | 2009 |
RhoA-Rho kinase signaling mediates endothelium- and endoperoxide-dependent contractile activities characteristic of hypertensive vascular dysfunction.
Topics: Amides; Animals; Carotid Artery, Common; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; Hypertension; In Vitro Techniques; Muscle Contraction; Muscle Proteins; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Contraction; Peroxides; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Thromboxane; rho-Associated Kinases; Signal Transduction | 2010 |
Simvastatin attenuated cerebrovascular cell proliferation in the development of hypertension through Rho/Rho-kinase pathway.
Topics: Amides; Animals; Basilar Artery; Blood Pressure; Cell Proliferation; Cerebrovascular Circulation; Disease Models, Animal; Endothelin-1; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Myocytes, Smooth Muscle; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin | 2012 |
Interleukin-17 causes Rho-kinase-mediated endothelial dysfunction and hypertension.
Topics: Amides; Animals; Endothelial Cells; Hypertension; Interleukin-17; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Pyridines; Rats; rho-Associated Kinases | 2013 |
Acute and chronic NOS inhibition enhances alpha(2)- adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta.
Topics: Adrenergic alpha-Agonists; Amides; Animals; Aorta; Brimonidine Tartrate; Enzyme Inhibitors; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Penicillamine; Protein Serine-Threonine Kinases; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasoconstriction | 2002 |
Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Angiotensin II; Animals; Cells, Cultured; Cyclic GMP; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Hypertension; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Muscle Proteins; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; NG-Nitroarginine Methyl Ester; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Threonine | 2003 |
Chronic inhibition of Rho kinase blunts the process of left ventricular hypertrophy leading to cardiac contractile dysfunction in hypertension-induced heart failure.
Topics: Amides; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gq-G11; Heart Failure; Heterotrimeric GTP-Binding Proteins; Hypertension; Hypertrophy, Left Ventricular; Intracellular Signaling Peptides and Proteins; Myocardium; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Ultrasonography | 2003 |
Comparison of inhibitory effects of Y-27632, a Rho kinase inhibitor, in strips of small and large mesenteric arteries from spontaneously hypertensive and normotensive Wistar-Kyoto rats.
Topics: Amides; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Enzyme Inhibitors; Hypertension; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; Vasoconstrictor Agents; Vasodilation | 2003 |
Rho/Rho-kinase pathway in brain stem contributes to blood pressure regulation via sympathetic nervous system: possible involvement in neural mechanisms of hypertension.
Topics: Adenoviridae; Amides; Animals; Blood Pressure; Blotting, Western; Brain Stem; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genetic Vectors; Heart Rate; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Microinjections; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Norepinephrine; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Solitary Nucleus; Sympathetic Nervous System; Transfection | 2003 |
Rho/Rho-kinase pathway in the brainstem contributes to hypertension caused by chronic nitric oxide synthase inhibition.
Topics: Amides; Animals; Blood Pressure; Enzyme Inhibitors; Hydralazine; Hypertension; Injections; Intracellular Signaling Peptides and Proteins; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred WKY; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Solitary Nucleus | 2004 |
Rho/Rho kinase and phosphoinositide 3-kinase are parallel pathways in the development of spontaneous arterial tone in deoxycorticosterone acetate-salt hypertension.
Topics: Amides; Animals; Arteries; Calcium; Chromones; Desoxycorticosterone; Enzyme Inhibitors; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Morpholines; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Vasoconstriction | 2004 |
Phosphodiesterase-5 inhibition synergizes rho-kinase antagonism and enhances erectile response in male hypertensive rats.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Amides; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Western; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Electric Stimulation; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Penile Erection; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Serine-Threonine Kinases; Purinones; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; rhoA GTP-Binding Protein; Up-Regulation | 2004 |
Cardioprotective mechanisms of Rho-kinase inhibition associated with eNOS and oxidative stress-LOX-1 pathway in Dahl salt-sensitive hypertensive rats.
Topics: Amides; Animals; Collagen Type I; Collagen Type III; Coronary Vessels; Enzyme Inhibitors; Fibronectins; Hypertension; Intracellular Signaling Peptides and Proteins; Male; NADPH Oxidases; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred Dahl; Receptors, LDL; Receptors, Oxidized LDL; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Scavenger Receptors, Class E; Signal Transduction; Transcription Factor RelA; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Rho-kinase inhibition suppresses bladder hyperactivity in spontaneously hypertensive rats.
Topics: Amides; Animals; Blood Pressure; Enzyme Inhibitors; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; rhoA GTP-Binding Protein; Urinary Bladder; Urinary Incontinence; Urodynamics | 2005 |
Mitogen-activated protein kinase contributes to elevated basal tone in aortic smooth muscle from hypertensive rats.
Topics: Amides; Animals; Aorta, Thoracic; Blood Pressure; Desoxycorticosterone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Hypertension; In Vitro Techniques; Indoles; Male; Maleimides; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth, Vascular; Phosphorylation; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin; Vasoconstriction; Vasodilator Agents; Verapamil | 2005 |
Regulation of vascular tone from spontaneously hypertensive rats by the HMG-CoA reductase inhibitor, simvastatin.
Topics: Amides; Animals; Aorta, Thoracic; Calcium Chloride; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; In Vitro Techniques; Indoles; Male; Mevalonic Acid; Muscle Relaxants, Central; Norepinephrine; Phenylephrine; Potassium Chloride; Pyridines; Rats; Rats, Inbred SHR; Simvastatin; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Relative contribution of Rho kinase and protein kinase C to myogenic tone in rat cerebral arteries in hypertension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amides; Animals; Benzophenanthridines; Blood Pressure; Calcium; Calcium Signaling; Cerebral Arteries; Enzyme Inhibitors; Hypertension; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Muscle Tonus; Muscle, Smooth, Vascular; Phenanthridines; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases | 2005 |
Augmented sphingosylphosphorylcholine-induced Ca2+-sensitization of mesenteric artery contraction in spontaneously hypertensive rat.
Topics: Amides; Animals; Calcium; Flavonoids; Hypertension; Mesenteric Arteries; Mitogen-Activated Protein Kinases; Myosin Light Chains; Naphthalenes; Phosphorylation; Phosphorylcholine; Protein Kinase C; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; Sphingosine; Vasoconstriction | 2006 |
Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats.
Topics: Amides; Angiotensin II; Animals; Aorta; Dose-Response Relationship, Drug; Enzyme Activation; Hypertension; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; NADPH Oxidases; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Vasoconstriction | 2006 |
Ovariectomy augments hypertension through rho-kinase activation in the brain stem in female spontaneously hypertensive rats.
Topics: Amides; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Western; Brain Stem; Enzyme Activation; Estradiol; Female; Heart Rate; Hypertension; Injections, Intraventricular; Intracellular Signaling Peptides and Proteins; Osmolar Concentration; Ovariectomy; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; rho-Associated Kinases; Telemetry | 2006 |
Re-expression of proteins involved in cytokinesis during cardiac hypertrophy.
Topics: Actomyosin; Amides; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; Calpain; Cardiomegaly; Cell Nucleus Division; Cullin Proteins; Cytokinesis; Heart; Hypertension; Intracellular Signaling Peptides and Proteins; Mice; Myocytes, Cardiac; Myofibrils; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred Dahl; rho GTP-Binding Proteins; rho-Associated Kinases; Up-Regulation | 2007 |
Enhanced stretch-induced myogenic tone in the basilar artery of spontaneously hypertensive rats.
Topics: Amides; Animals; Baroreflex; Basilar Artery; Calcium; Disease Models, Animal; Hypertension; Intracellular Signaling Peptides and Proteins; Mechanotransduction, Cellular; Pressoreceptors; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasoconstriction | 2007 |
Increased PDZ-RhoGEF/RhoA/Rho kinase signaling in small mesenteric arteries of angiotensin II-induced hypertensive rats.
Topics: Amides; Angiotensin II; Animals; Base Sequence; Calcium; DNA Primers; Guanine Nucleotide Exchange Factors; Hypertension; Immunoprecipitation; Mesenteric Arteries; Myosin-Light-Chain Phosphatase; Protein Transport; Pyridines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; rhoA GTP-Binding Protein; Signal Transduction | 2007 |
Evidence that Rho-kinase activity contributes to cerebral vascular tone in vivo and is enhanced during chronic hypertension: comparison with protein kinase C.
Topics: Amides; Animals; Basilar Artery; Blood Pressure; Cerebral Arteries; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Intracellular Signaling Peptides and Proteins; Male; NG-Nitroarginine Methyl Ester; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; rho-Associated Kinases; Species Specificity; Vasodilator Agents; Vasomotor System | 2001 |
Enhanced relaxation to the rho-kinase inhibitor Y-27632 in mesenteric arteries from mineralocorticoid hypertensive rats.
Topics: Amides; Animals; Desoxycorticosterone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Mesenteric Arteries; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Serotonin; Vasodilation | 2001 |
Decreased penile erection in DOCA-salt and stroke prone-spontaneously hypertensive rats.
Topics: Amides; Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Electric Stimulation; Ganglia; Genetic Predisposition to Disease; Hypertension; Male; Pelvis; Penile Erection; Penis; Pyridines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Sodium Chloride; Stroke | 2001 |
Long-term effects of benidipine on cerebral vasoreactivity in hypertensive rats.
Topics: Acetylcholine; Amides; Animals; Basilar Artery; Body Weight; Calcium Channel Blockers; Cerebral Arteries; Dihydropyridines; Dose-Response Relationship, Drug; Hypertension; Male; Muscle Relaxants, Central; Nitric Oxide Donors; Nitroprusside; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Vasodilation; Vasodilator Agents | 2002 |
Involvement of Rho-kinase pathway for angiotensin II-induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats.
Topics: Amides; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Body Weight; Hemodynamics; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organ Size; Plasminogen Activator Inhibitor 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Inbred WKY; rho-Associated Kinases; rhoA GTP-Binding Protein; Ribosomal Protein S6 Kinases; RNA, Messenger; Tetrazoles; Ventricular Remodeling | 2002 |
Increased activity of calcium channels and Rho-associated kinase in the basilar artery during chronic hypertension in vivo.
Topics: Acetylcholine; Amides; Animals; Antihypertensive Agents; Basilar Artery; Calcium Channel Blockers; Calcium Channels; Chronic Disease; Enzyme Inhibitors; Hypertension; Intracellular Signaling Peptides and Proteins; NG-Nitroarginine Methyl Ester; Nicardipine; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; Serotonin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2002 |