Compounds > y 27632

Page last updated: 2024-09-03

y 27632 and Asthma

y 27632 has been researched along with Asthma in 17 studies

Research

Studies (17)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	9 (52.94)	29.6817
2010's	8 (47.06)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hajizadeh, S; Javan, M; Pazhoohan, S; Raoufy, MR	1
Aimbire, F; Castro-Faria-Neto, HC; de Oliveira, AP; Marcondes, P; Silva, M; Silva, VR; Vieira, RP; Villaverde, AB	1
Antunes, MA; dos Santos, AS; Leick, EA; Martins, Mde A; Pigati, PA; Possa, SS; Prado, CM; Righetti, RF; Rocco, PR; Rodrigues, AP; Romanholo, BS; Tibério, Ide F; Xisto, DG	1
Fernandes, LB; Goldie, RG; Henry, PJ	1
Chiba, Y; Hanazaki, M; Kohjitani, A; Misawa, M; Morita, K; Sakai, H; Yokoyama, M	1
George, SC; Jiang, J	1
Cheng, YX; Lai, WY; Li, N; Li, X; Meng, Y; Niu, Y; Shen, B	1
Jiao, Y; Paré, PD; Raqeeb, A; Seow, CY; Syyong, HT	1
Hasegawa, Y; Honjo, H; Kamiya, K; Kume, H; Makino, Y; Oguma, T; Shiraki, A; Sugishita, M	1
Almeida-Reis, R; Charafeddine, HT; da Silva, PA; Leick-Maldonado, EA; Martins, MA; Perini, A; Possa, SS; Prado, CM; Righetti, RF; Saraiva-Romanholo, BM; Tibério, Ide F	1
Aihara, M; Dobashi, K; Iizuka, K; Mori, M; Nakazawa, T	1
Honjo, H; Ito, S; Kamiya, K; Kodama, I; Kume, H; Oguma, T; Shimokata, K; Takeda, N	1
Bos, IS; Meurs, H; Schaafsma, D; Zaagsma, J; Zuidhof, AB	2
Chen, P; Gan, Y; Wu, SJ; Xiang, XD; Xing, XQ; Zhou, R	1
Ahrens, B; Hamelmann, E; Hippenstiel, S; Kube, SM; Rosseau, S; Schmeck, B; Schütte, H; Suttorp, N; Witzenrath, M	1
Ichinose, M; Koarai, A; Koike, K; Shirato, K; Sugiura, H; Yamagata, S	1

Reviews

1 review(s) available for y 27632 and Asthma

Article	Year
Rho kinase as a therapeutic target in the treatment of asthma and chronic obstructive pulmonary disease. Therapeutic advances in respiratory disease, 2007, Volume: 1, Issue:1 Topics: Amides; Animals; Asthma; Enzyme Inhibitors; Humans; Pulmonary Disease, Chronic Obstructive; Pyridines; rho-Associated Kinases	2007

Other Studies

16 other study(ies) available for y 27632 and Asthma

Article	Year
Effect of Rho-kinase inhibition on complexity of breathing pattern in a guinea pig model of asthma. PloS one, 2017, Volume: 12, Issue:10 Topics: Amides; Animals; Asthma; Disease Models, Animal; Guinea Pigs; Male; Plethysmography, Whole Body; Pyridines; Respiration; Respiratory Physiological Phenomena; rho-Associated Kinases	2017
Low-level laser therapy inhibits bronchoconstriction, Th2 inflammation and airway remodeling in allergic asthma. Respiratory physiology & neurobiology, 2014, Apr-01, Volume: 194 Topics: Airway Remodeling; Amides; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Cytokines; Enzyme Inhibitors; Hypersensitivity; Low-Level Light Therapy; Lung; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth; Ovalbumin; Pneumonia; Pyridines; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; STAT6 Transcription Factor	2014
Y-27632 is associated with corticosteroid-potentiated control of pulmonary remodeling and inflammation in guinea pigs with chronic allergic inflammation. BMC pulmonary medicine, 2015, Aug-12, Volume: 15 Topics: Airway Remodeling; Amides; Animals; Asthma; Chronic Disease; Disease Models, Animal; Drug Synergism; Enzyme Inhibitors; Glucocorticoids; Guinea Pigs; Inflammation; Lung; Pyridines	2015
Y-27632 augments the isoflurane-induced relaxation of bronchial smooth muscle in rats. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2008, Volume: 44, Issue:6 Topics: Acetylcholine; Amides; Anesthetics, Inhalation; Animals; Asthma; Bronchi; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Isoflurane; Male; Muscle Relaxation; Muscle, Smooth; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction	2008
TGF-β2 reduces nitric oxide synthase mRNA through a ROCK-dependent pathway in airway epithelial cells. American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 301, Issue:3 Topics: Amides; Arginase; Arginine; Asthma; Cell Line; Epithelial Cells; Humans; Lung; Nitric Oxide Synthase; Pyridines; rho-Associated Kinases; RNA, Messenger; Transforming Growth Factor beta2	2011
[Activation of Rho-kinase pathway is involved in angiotensin II-induced contraction of human airway smooth muscle cells]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2011, Volume: 31, Issue:8 Topics: Amides; Angiotensin II; Asthma; Biphenyl Compounds; Bronchi; Humans; Irbesartan; Muscle Contraction; Muscle, Smooth; Primary Cell Culture; Pyridines; rho-Associated Kinases; Signal Transduction; Tetrazoles	2011
Regulatable stiffness in relaxed airway smooth muscle: a target for asthma treatment? Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 112, Issue:3 Topics: Amides; Animals; Asthma; Azepines; Calcium; Imidazoles; In Vitro Techniques; Molecular Targeted Therapy; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myosin-Light-Chain Kinase; Naphthalenes; Phosphorylation; Pyridines; rho-Associated Kinases; Sheep; Signal Transduction; Trachea	2012
Role of sphingosine-1-phosphate inβ-adrenoceptor desensitization via Ca(2+) sensitization in airway smooth muscle. Allergology international : official journal of the Japanese Society of Allergology, 2012, Volume: 61, Issue:2 Topics: Adrenergic beta-Agonists; Amides; Animals; Asthma; Calcium Signaling; Cells, Cultured; Guinea Pigs; Humans; Isoproterenol; Lysophospholipids; Myocytes, Smooth Muscle; Pertussis Toxin; Pyridines; Receptors, Adrenergic, beta; rho-Associated Kinases; Sphingosine; Trachea	2012
Rho-kinase inhibition attenuates airway responsiveness, inflammation, matrix remodeling, and oxidative stress activation induced by chronic inflammation. American journal of physiology. Lung cellular and molecular physiology, 2012, Dec-01, Volume: 303, Issue:11 Topics: Airway Remodeling; Airway Resistance; Amides; Animals; Anti-Asthmatic Agents; Asthma; Collagen; Dinoprost; Drug Evaluation, Preclinical; Elastic Tissue; Elasticity; Eosinophils; Extracellular Matrix; Guinea Pigs; Inhalation; Interleukin-2; Lung; Male; Matrix Metalloproteinase 9; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Pyridines; rho-Associated Kinases	2012
Effect of Y-27632 on release of cytokines from peripheral T cells in asthmatic patients and normal subjects. International immunopharmacology, 2004, Volume: 4, Issue:4 Topics: Adult; Amides; Asthma; Cells, Cultured; Concanavalin A; Cytokines; Dose-Response Relationship, Drug; Female; Humans; Interferon-gamma; Interleukin-2; Interleukin-4; Interleukin-5; Intracellular Signaling Peptides and Proteins; Male; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; T-Lymphocytes; Th1 Cells; Th2 Cells	2004
Involvement of reduced sensitivity to Ca in beta-adrenergic action on airway smooth muscle. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:2 Topics: Adrenergic beta-Agonists; Amides; Animals; Asthma; Bucladesine; Calcium; Calcium Channel Blockers; Colforsin; Cyclic AMP Receptor Protein; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Fura-2; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Maleimides; Marine Toxins; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Phosphatase; Oxazoles; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Trachea	2006
Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction. Respiratory research, 2006, Sep-26, Volume: 7 Topics: Administration, Inhalation; Amides; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Enzyme Inhibitors; Guinea Pigs; Intracellular Signaling Peptides and Proteins; Male; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Treatment Outcome	2006
Therapeutic potential of Rho-kinase inhibitors in asthma. Medical hypotheses, 2007, Volume: 68, Issue:3 Topics: Amides; Asthma; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases	2007
Rho-kinase and contractile apparatus proteins in murine airway hyperresponsiveness. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2008, Volume: 60, Issue:1 Topics: Amides; Animals; Asthma; Blotting, Western; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Enzyme Inhibitors; Female; Lung; Mice; Mice, Inbred BALB C; Muscle, Smooth; Myosin Light Chains; Myosin-Light-Chain Kinase; Ovalbumin; Perfusion; Phosphorylation; Pyridines; rho-Associated Kinases	2008
The inhaled Rho kinase inhibitor Y-27632 protects against allergen-induced acute bronchoconstriction, airway hyperresponsiveness, and inflammation. American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 295, Issue:1 Topics: Acute Disease; Allergens; Amides; Animals; Asthma; Disease Models, Animal; Enzyme Inhibitors; Guinea Pigs; Inflammation; Male; Neutrophils; Pyridines; rho-Associated Kinases; Time Factors	2008
Effect of a calcium sensitization modulator, Y-27632, on isolated human bronchus and pulmonary artery. Pulmonary pharmacology & therapeutics, 2000, Volume: 13, Issue:1 Topics: Amides; Analysis of Variance; Asthma; Bronchi; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Muscle Relaxants, Central; Muscle, Smooth; Muscle, Smooth, Vascular; Pulmonary Artery; Pyridines; Vasodilation	2000