y 27632 and Alloxan Diabetes

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cardiomyopathies; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Humans; Mice; Oxidative Stress; Pyridines; Rats; rho-Associated Kinases; Sexual Dysfunction, Physiological; Signal Transduction; Vasodilator Agents

Topics: Aging; Amides; Anesthetics, Inhalation; Animals; Aorta; Chromones; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Isoflurane; Morpholines; Phosphatidylinositol 3-Kinases; Potassium Chloride; Pyridines; Rats, Inbred OLETF; Rats, Wistar; rho-Associated Kinases; Sevoflurane; Vasoconstriction

Topics: Adaptor Proteins, Signal Transducing; Amides; Animals; Cell Cycle Proteins; Chromones; Diabetes Mellitus, Experimental; ErbB Receptors; Fibrosis; Gene Expression Regulation; HEK293 Cells; Humans; Kidney Diseases; Mice; Mice, Knockout; Morpholines; Nitric Oxide Synthase Type III; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Transcription Factors; YAP-Signaling Proteins

Topics: Acetylcholine; Amides; Angiotensin II; Animals; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Male; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyridines; rho-Associated Kinases; Streptozocin; Time Factors

Topics: Amides; Animals; Complement C3; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type III; Pain Threshold; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin; Spinal Cord; Streptozocin; Time Factors

Topics: Amides; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chloride; Carbachol; Cholinergic Agonists; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Nifedipine; Pyridines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Purinergic P2X1; rho-Associated Kinases; RNA, Messenger; Urinary Bladder Diseases

Topics: Albuminuria; Amides; Animals; Diabetes Mellitus, Experimental; Mice; Mice, Knockout; Pyridines; rho-Associated Kinases

Topics: Amides; Animals; Apoptosis; Caspase 3; Diabetes Mellitus, Experimental; Gene Expression Regulation; Intravitreal Injections; Male; Nerve Growth Factor; Nerve Tissue Proteins; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Primary Cell Culture; Protein Kinase Inhibitors; Protein Precursors; Proteolysis; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Growth Factor; Receptors, Nerve Growth Factor; Retinal Degeneration; Retinal Ganglion Cells; rhoA GTP-Binding Protein; Signal Transduction; Streptozocin

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Muscle Relaxation; Penis; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases

Topics: Adenoviridae; Amides; Animals; Blood Glucose; Body Weight; Cyclic GMP; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Erectile Dysfunction; Gene Expression; Intracellular Signaling Peptides and Proteins; Male; Muscle Relaxants, Central; Myosin-Light-Chain Phosphatase; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Penis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Transfection

Topics: Amides; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diuresis; Diuretics; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Intracellular Signaling Peptides and Proteins; Muscle Proteins; Muscle, Smooth; Myosins; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; Urinary Bladder

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Aorta; Cells, Cultured; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glucose; Immunoblotting; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Male; Maleimides; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Up-Regulation

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Amides; Animals; Blotting, Western; Cell Survival; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Echocardiography; Enzyme Activation; Intracellular Signaling Peptides and Proteins; Lim Kinases; Male; Myocardial Contraction; Myocytes, Cardiac; Perfusion; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases

Topics: Alloxan; Amides; Animals; Blotting, Western; Diabetes Mellitus, Experimental; Disease Models, Animal; Erectile Dysfunction; Hypogonadism; Intracellular Signaling Peptides and Proteins; Male; Penis; Protein Serine-Threonine Kinases; Pyridines; Rabbits; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; Streptozocin; Testosterone; Up-Regulation

Topics: Amides; Angiotensin II; Animals; Arterioles; C-Peptide; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Kidney Glomerulus; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Norepinephrine; Potassium Chloride; Pyridines; Rho Factor; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents