y 27632 has been researched along with Aging in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (45.00) | 29.6817 |
| 2010's | 9 (45.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, S; Jin, F; Liu, Y; Qi, F; Yang, S | 1 |
| Fisher, ES; Manley, L; Temple, S; Wang, Y; Zhao, X; Zuloaga, K | 1 |
| Chess-Williams, R; Lim, I; Sellers, D | 1 |
| Cohen, H; Horvath, S; Lu, AT; Raj, K | 1 |
| He, L; Kang, S; Ling, QL; Liu, JG; Liu, WT; Liu, Y; Lu, B | 1 |
| Seawright, JW; Trache, A; Wilson, E; Woodman, CR | 1 |
| Cherasse, Y; Deguchi, Y; Furuyashiki, T; Harada, M; Lazarus, M; Narumiya, S; Sekiguchi, M; Shinohara, R; Urade, Y; Watanabe, D; Yamada, D | 1 |
| Cheung, J; Gossan, N; Hughes, A; McConnell, J; Meng, QJ; Olabi, S; Pekovic-Vaughan, V; Streuli, CH; Wang, P; Williams, J; Yang, N | 1 |
| Engelberts, D; Ivanovska, J; Jankov, RP; Kantores, C; Kavanagh, BP; McNamara, PJ; Xu, EZ | 1 |
| Camello, PJ; Camello-Almaraz, C; Gomez-Pinilla, PJ; Macias, B; Pascua, P; Pozo, MJ; Tresguerres, JA | 1 |
| Hoshino, Y; Ishigami, A; Machii, H; Misaka, T; Miyata, M; Mizukami, H; Saitoh, S; Takeishi, Y; Yamada, S | 1 |
| Jin, L; Linder, AE; Mills, TM; Webb, RC | 1 |
| Fujikawa, A; Katsuura, G; Komai, S; Manabe, T; Niisato, K; Noda, M; Sakaguchi, G; Shintani, T; Watanabe, E | 1 |
| Cogolludo, A; Lodi, F; Moreno, L; Perez-Vizcaino, F; Tamargo, J | 1 |
| Hester, RL; Naik, JS; Xiang, L | 1 |
| Belik, J; Kerc, E; Pato, MD | 1 |
| Bivalacqua, TJ; Burnett, AL; Champion, HC; Jin, L; Lagoda, GA; Liu, T | 1 |
| Blough, ER; Desai, DH; Rice, KM; Wehner, P; Wright, GL | 1 |
| Gao, BH; Liu, YQ; Meng, FW; Shi, BK; Xu, ZS; Zhao, ST | 1 |
| Andersson, KE; Camello, PJ; Gomez, MF; Gomez-Pinilla, PJ; Hedlund, P; Hellstrand, P; Pozo, MJ; Swärd, K | 1 |
1 review(s) available for y 27632 and Aging
| Article | Year |
|---|---|
Inhibition of the tonic contraction in the treatment of erectile dysfunction.
Topics: Adrenergic Agonists; Adult; Aged; Aging; Amides; Angiotensin II; Calcium Signaling; Cyclic AMP; Endothelin-1; Erectile Dysfunction; Forecasting; Humans; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Penis; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasoactive Intestinal Peptide | 2003 |
19 other study(ies) available for y 27632 and Aging
| Article | Year |
|---|---|
Sevoflurane and isoflurane inhibit KCl-induced, Rho kinase-mediated, and PI3K-participated vasoconstriction in aged diabetic rat aortas.
Topics: Aging; Amides; Anesthetics, Inhalation; Animals; Aorta; Chromones; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Isoflurane; Morpholines; Phosphatidylinositol 3-Kinases; Potassium Chloride; Pyridines; Rats, Inbred OLETF; Rats, Wistar; rho-Associated Kinases; Sevoflurane; Vasoconstriction | 2021 |
4D imaging analysis of the aging mouse neural stem cell niche reveals a dramatic loss of progenitor cell dynamism regulated by the RHO-ROCK pathway.
Topics: Aging; Amides; Animals; Cell Movement; Lateral Ventricles; Mice; Mice, Transgenic; Neural Stem Cells; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Stem Cell Niche; Time-Lapse Imaging | 2022 |
Altered ureteral contractility with ageing: Role of the rho-kinase pathway.
Topics: Aging; Amides; Animals; Dose-Response Relationship, Drug; Female; Mice; Muscle Contraction; Phenylephrine; Pyridines; rho-Associated Kinases; Serotonin; Swine; Ureter | 2018 |
Rapamycin retards epigenetic ageing of keratinocytes independently of its effects on replicative senescence, proliferation and differentiation.
Topics: Aging; Amides; Cell Differentiation; Cell Proliferation; Cellular Senescence; Drug Evaluation, Preclinical; Epigenesis, Genetic; Humans; Keratinocytes; Primary Cell Culture; Pyridines; rho-Associated Kinases; Sirolimus; Telomere Homeostasis; TOR Serine-Threonine Kinases | 2019 |
Down-regulation of dorsal striatal RhoA activity and impairment of working memory in middle-aged rats.
Topics: Age Factors; Aging; Amides; Animals; Corpus Striatum; Down-Regulation; Enzyme Inhibitors; Maze Learning; Memory, Short-Term; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2013 |
Short-duration increases in intraluminal pressure improve vasoconstrictor responses in aged skeletal muscle feed arteries.
Topics: Aging; Amides; Angiotensin II; Animals; Arteries; Endothelium, Vascular; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Physical Conditioning, Animal; Pressure; Pyridines; Rats; Rats, Inbred F344; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents | 2016 |
mDia and ROCK Mediate Actin-Dependent Presynaptic Remodeling Regulating Synaptic Efficacy and Anxiety.
Topics: Actin Cytoskeleton; Actins; Aging; Amides; Animals; Anxiety; Behavior, Animal; Brain; Carrier Proteins; Cells, Cultured; Formins; GABAergic Neurons; Mice, Inbred C57BL; Nucleus Accumbens; Optogenetics; Phenotype; Presynaptic Terminals; Pyridines; rho-Associated Kinases; Social Isolation; Ventral Tegmental Area | 2016 |
Cellular mechano-environment regulates the mammary circadian clock.
Topics: Aging; Amides; Animals; Breast; Breast Diseases; Cell Self Renewal; Cellular Microenvironment; Circadian Clocks; Circadian Rhythm; CLOCK Proteins; Epithelial Cells; Epithelium; Extracellular Matrix; Female; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Primary Cell Culture; Pyridines; rho-Associated Kinases; RNA, Small Interfering; Signal Transduction; Spheroids, Cellular; Tissue Culture Techniques; Vinculin | 2017 |
Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Age Factors; Aging; Amides; Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Chronic Disease; Disease Models, Animal; Endothelin-1; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Injections, Subcutaneous; Muscle, Smooth, Vascular; Myocardium; Protein Kinase Inhibitors; Pulmonary Artery; Pyridines; Rats; Receptor, Endothelin A; rho-Associated Kinases; RNA Interference; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling | 2010 |
Aging impairs Ca2+ sensitization pathways in gallbladder smooth muscle.
Topics: Aging; Amides; Analysis of Variance; Animals; Bethanechol; Blotting, Western; Calcium Channels; Calcium Signaling; Cholecystokinin; Female; Gallbladder; Guinea Pigs; Isometric Contraction; Melatonin; Models, Animal; Muscle, Smooth; Oxidative Stress; Phosphorylation; Pyridines; Signal Transduction | 2012 |
Age-related oxidant stress with senescence marker protein-30 deficiency plays a pivotal role in coronary artery spasm.
Topics: Aging; Amides; Animals; Aorta; Ascorbic Acid; Calcium-Binding Proteins; Coronary Vasospasm; Coronary Vessels; Electrocardiography; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Pyridines; Reactive Oxygen Species; rho-Associated Kinases; Serotonin; Serotonin Receptor Agonists; Sulfhydryl Compounds; Vasoconstriction; Vasodilation | 2013 |
Age-dependent enhancement of hippocampal long-term potentiation and impairment of spatial learning through the Rho-associated kinase pathway in protein tyrosine phosphatase receptor type Z-deficient mice.
Topics: Aging; Amides; Animals; Chondroitin Sulfate Proteoglycans; Enzyme Activation; Excitatory Postsynaptic Potentials; Hippocampus; Intracellular Signaling Peptides and Proteins; Long-Term Potentiation; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Phenotype; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Pyridines; Receptor-Like Protein Tyrosine Phosphatases, Class 5; Receptors, Cell Surface; rho-Associated Kinases; Signal Transduction | 2005 |
Postnatal maturational shift from PKCzeta and voltage-gated K+ channels to RhoA/Rho kinase in pulmonary vasoconstriction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Aging; Amides; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Endothelium, Vascular; In Vitro Techniques; Isoenzymes; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Protein Kinase C; Pulmonary Artery; Pyridines; rhoA GTP-Binding Protein; Signal Transduction; Swine; Thromboxane A2 | 2005 |
Enhanced role for RhoA-associated kinase in adrenergic-mediated vasoconstriction in gracilis arteries from obese Zucker rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic Agents; Aging; Amides; Animals; Arteries; Calcium Signaling; Gene Expression Regulation; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Obesity; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Zucker; rho-Associated Kinases; rhoA GTP-Binding Protein; Thinness; Vasoconstriction | 2006 |
Rat pulmonary arterial smooth muscle myosin light chain kinase and phosphatase activities decrease with age.
Topics: Aging; Amides; Animals; Animals, Newborn; Enzyme Inhibitors; Female; Fetus; Gene Expression Regulation, Developmental; Intracellular Signaling Peptides and Proteins; Muscle Relaxation; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Myosin-Light-Chain Phosphatase; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Protein Subunits; Pulmonary Artery; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases | 2006 |
Elevated RhoA/Rho-kinase activity in the aged rat penis: mechanism for age-associated erectile dysfunction.
Topics: Aging; Amides; Amino Acid Substitution; Animals; Dependovirus; Erectile Dysfunction; Genetic Therapy; Genetic Vectors; Intracellular Signaling Peptides and Proteins; Isoenzymes; Male; Muscle Contraction; Muscle, Smooth, Vascular; Mutation, Missense; Myosin-Light-Chain Phosphatase; Penis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred F344; Recombinant Fusion Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasodilation | 2006 |
Aging alters mechanical and contractile properties of the Fisher 344/Nnia X Norway/Binia rat aorta.
Topics: Aging; Amides; Animals; Aorta; Biomechanical Phenomena; Endothelium, Vascular; Enzyme Inhibitors; Male; Models, Animal; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Heavy Chains; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Potassium; Pyridines; Rats; Rats, Inbred BN; Rats, Inbred F344 | 2007 |
Y-27632 improves the erectile dysfunction with ageing in SD rats through adjusting the imbalance between nNo and the Rho-kinase pathways.
Topics: Aging; Amides; Animals; Erectile Dysfunction; Intracellular Signaling Peptides and Proteins; Male; Models, Molecular; Nitric Oxide Synthase Type I; Penile Erection; Penis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases | 2007 |
Melatonin restores impaired contractility in aged guinea pig urinary bladder.
Topics: Aging; Amides; Animals; Antioxidants; Calcium; Calcium Signaling; Enzyme Inhibitors; Female; Gene Expression Regulation; Guinea Pigs; Indoles; Isometric Contraction; Maleimides; Melatonin; Myosin-Light-Chain Phosphatase; Phosphorylation; Protein Kinase C; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Urinary Bladder; Urinary Bladder Diseases | 2008 |