xylometazoline has been researched along with Rhinitis in 36 studies
xylometazoline: RN given refers to parent cpd; structure
Rhinitis: Inflammation of the NASAL MUCOSA, the mucous membrane lining the NASAL CAVITIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our study is a first in investigating the combined use of large volume low pressure nasal saline and fluticasone propionate in acute pediatric rhinosinusitis, and the results reveal that the combination therapy was effective." | 9.19 | The use of large volume low pressure nasal saline with fluticasone propionate for the treatment of pediatric acute rhinosinusitis. ( Dogan, R; Eren, SB; Meric, A; Ozturan, O; Tugrul, S, 2014) |
| "This randomised, double-blind, multi-centered, verum-controlled tolerance study confirmed that the local sympathomimetics oxymetazoline and xylometazoline are well tolerated in the treatment of acute rhinitis." | 9.10 | [Tolerance and effectiveness of oxymetazoline and xylometazoline in treatment of acute rhinitis]. ( Dorn, M; Hofmann, W; Knick, E, 2003) |
| "The addition of fluticasone to xylometazoline and antimicrobial therapy with cefuroxime improves clinical success rates and accelerates recovery of patients with a history of chronic rhinitis or recurrent sinusitis who present for treatment of acute rhinosinusitis." | 9.09 | Comparison of cefuroxime with or without intranasal fluticasone for the treatment of rhinosinusitis. The CAFFS Trial: a randomized controlled trial. ( Califf, RM; Dolor, RJ; Hellkamp, AS; Simel, DL; Williams, JW; Witsell, DL, 2001) |
| "The relative bioavailability of nicotine from a nasal spray was assessed in 15 smokers suffering a common cold and rhinitis according to generally accepted criteria." | 9.08 | Relative bioavailability of nicotine from a nasal spray in infectious rhinitis and after use of a topical decongestant. ( Andersson, M; Lunell, E; Molander, L, 1995) |
| "this is the first report in the literature of posterior circulation strokes because of chronic xylometazoline abuse." | 7.77 | Xylometazoline abuse induced ischemic stroke in a young adult. ( Leupold, D; Wartenberg, KE, 2011) |
| "Acute Rhinitis is based on an inflammation of the nasal mucous membrane with nasal discharge and obstruction." | 6.71 | [Advance in therapy of acute rhinitis--comparison of efficacy and safety of xylometazoline in combination xylometazoline-dexpanthenol in patients with acute rhinitis]. ( Dethlefsen, U; Kehrl, W; Sonnemann, U, 2003) |
| " The risk of severe side effects with xylometazoline in young children is low if the dosage is adequate." | 5.72 | [Nasal toilet in infants with rhinitis: nasal passage crucial, so treat with xylometazoline]. ( Klok, T; Mensink, MHA; Videler, W; Wieringa, N, 2022) |
| "Our study is a first in investigating the combined use of large volume low pressure nasal saline and fluticasone propionate in acute pediatric rhinosinusitis, and the results reveal that the combination therapy was effective." | 5.19 | The use of large volume low pressure nasal saline with fluticasone propionate for the treatment of pediatric acute rhinosinusitis. ( Dogan, R; Eren, SB; Meric, A; Ozturan, O; Tugrul, S, 2014) |
| "This randomised, double-blind, multi-centered, verum-controlled tolerance study confirmed that the local sympathomimetics oxymetazoline and xylometazoline are well tolerated in the treatment of acute rhinitis." | 5.10 | [Tolerance and effectiveness of oxymetazoline and xylometazoline in treatment of acute rhinitis]. ( Dorn, M; Hofmann, W; Knick, E, 2003) |
| " The result of this controlled clinical study confirms that the combination Xylometazoline-Dexpanthenol is an enlargement and improvement of effective medicinal treatment of rhinitis following nasal operation in comparison to therapy with Xylometazoline alone." | 5.09 | [Improving wound healing after nose surgery by combined administration of xylometazoline and dexpanthenol]. ( Kehrl, W; Sonnemann, U, 2000) |
| "The addition of fluticasone to xylometazoline and antimicrobial therapy with cefuroxime improves clinical success rates and accelerates recovery of patients with a history of chronic rhinitis or recurrent sinusitis who present for treatment of acute rhinosinusitis." | 5.09 | Comparison of cefuroxime with or without intranasal fluticasone for the treatment of rhinosinusitis. The CAFFS Trial: a randomized controlled trial. ( Califf, RM; Dolor, RJ; Hellkamp, AS; Simel, DL; Williams, JW; Witsell, DL, 2001) |
| "The relative bioavailability of nicotine from a nasal spray was assessed in 15 smokers suffering a common cold and rhinitis according to generally accepted criteria." | 5.08 | Relative bioavailability of nicotine from a nasal spray in infectious rhinitis and after use of a topical decongestant. ( Andersson, M; Lunell, E; Molander, L, 1995) |
| "this is the first report in the literature of posterior circulation strokes because of chronic xylometazoline abuse." | 3.77 | Xylometazoline abuse induced ischemic stroke in a young adult. ( Leupold, D; Wartenberg, KE, 2011) |
| "The aim was to study changes in sales and prescribing of nasal decongestants containing oxymetazoline or xylometazoline, changes in number of physician visits for rhinitis and sinusitis, and changes in public expenditures for physician visits due to the switch of these drugs from prescription to over-the-counter status in Sweden in 1989." | 3.70 | The impact of over-the-counter availability of nasal sprays on sales, prescribing, and physician visits. ( Isacson, D; Lundberg, L, 1999) |
| " The aims of this study were to determine the degree of this asymmetry in healthy subjects and those with acute rhinitis associated with common cold, and to investigate how the administration of a topical nasal decongestant (xylometazoline) influenced the asymmetry in NAR." | 3.68 | Nasal airflow asymmetry and the effects of a topical nasal decongestant. ( Eccles, R; Williams, RG, 1992) |
| "Twenty healthy subjects were treated with xylometazoline 1 mg/ml for six weeks in order to study the occurrence of tachyphylaxis and rhinitis medicamentosa." | 3.66 | Treatment with xylometazoline (Otrivin) nosedrops over a six-week period. ( Petruson, B, 1981) |
| "Whether nasal congestion promotes obstructive sleep apnea is controversial." | 2.73 | Does nasal decongestion improve obstructive sleep apnea? ( Bloch, KE; Clarenbach, CF; Kohler, M; Senn, O; Thurnheer, R, 2008) |
| "Acute Rhinitis is based on an inflammation of the nasal mucous membrane with nasal discharge and obstruction." | 2.71 | [Advance in therapy of acute rhinitis--comparison of efficacy and safety of xylometazoline in combination xylometazoline-dexpanthenol in patients with acute rhinitis]. ( Dethlefsen, U; Kehrl, W; Sonnemann, U, 2003) |
| " The risk of severe side effects with xylometazoline in young children is low if the dosage is adequate." | 1.72 | [Nasal toilet in infants with rhinitis: nasal passage crucial, so treat with xylometazoline]. ( Klok, T; Mensink, MHA; Videler, W; Wieringa, N, 2022) |
| "Nasal obstruction is caused by rebound swelling when the decongestive effect has disappeared." | 1.33 | [Ultrastructural changes in human nasal mucosa in rhinitis medicamentosa]. ( Bloching, M; Holzhausen, HJ; Knipping, S; Riederer, A, 2006) |
| " We conclude that long-term use of xylometazoline nasal spray shortens the decongestive response in healthy volunteers." | 1.29 | Sustained use of xylometazoline nasal spray shortens the decongestive response and induces rebound swelling. ( Graf, P; Juto, JE, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (30.56) | 18.7374 |
| 1990's | 8 (22.22) | 18.2507 |
| 2000's | 8 (22.22) | 29.6817 |
| 2010's | 7 (19.44) | 24.3611 |
| 2020's | 2 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Mensink, MHA | 1 |
| Wieringa, N | 1 |
| Videler, W | 1 |
| Klok, T | 1 |
| Pham, H | 1 |
| Gosselin-Lefebvre, S | 1 |
| Pourshahnazari, P | 1 |
| Yip, S | 1 |
| Mösges, R | 1 |
| Shah-Hosseini, K | 1 |
| Hucke, HP | 1 |
| Joisten, MJ | 1 |
| Cingi, C | 1 |
| Birdane, L | 1 |
| Ural, A | 1 |
| Oghan, F | 1 |
| Bal, C | 1 |
| Tugrul, S | 1 |
| Dogan, R | 1 |
| Eren, SB | 1 |
| Meric, A | 1 |
| Ozturan, O | 1 |
| Mishra, AK | 1 |
| Sinha, VR | 1 |
| Nilakantan, A | 1 |
| Singh, DK | 1 |
| Clarenbach, CF | 1 |
| Kohler, M | 1 |
| Senn, O | 1 |
| Thurnheer, R | 1 |
| Bloch, KE | 1 |
| Leupold, D | 1 |
| Wartenberg, KE | 1 |
| Bielenberg, J | 1 |
| Mi, J | 1 |
| Fan, Y | 1 |
| Feng, S | 1 |
| Xia, W | 1 |
| Wang, J | 1 |
| Li, H | 1 |
| Kehrl, W | 2 |
| Sonnemann, U | 2 |
| Dethlefsen, U | 1 |
| CZYSCH, H | 1 |
| KELLER, D | 1 |
| ASCHAN, G | 2 |
| DRETTNER, B | 2 |
| Dorn, M | 1 |
| Hofmann, W | 1 |
| Knick, E | 1 |
| Ammerschläger, H | 1 |
| Klein, P | 1 |
| Weiser, M | 1 |
| Oberbaum, M | 1 |
| Michel, O | 1 |
| Essers, S | 1 |
| Heppt, WJ | 1 |
| Johannssen, V | 1 |
| Reuter, W | 1 |
| Hommel, G | 1 |
| Knipping, S | 1 |
| Holzhausen, HJ | 1 |
| Riederer, A | 1 |
| Bloching, M | 1 |
| Myklebust, G | 1 |
| Sandvik, L | 1 |
| Frostad, AB | 1 |
| Cole, P | 1 |
| Fastag, O | 1 |
| Forsyth, R | 1 |
| Petruson, B | 4 |
| Ekedahl, C | 2 |
| Geterud, A | 2 |
| Aust, R | 2 |
| Odkvist, L | 2 |
| Graf, P | 2 |
| Juto, JE | 1 |
| Lunell, E | 1 |
| Molander, L | 1 |
| Andersson, M | 1 |
| Wilhelmson, B | 1 |
| Lundberg, L | 1 |
| Isacson, D | 1 |
| Dolor, RJ | 1 |
| Witsell, DL | 1 |
| Hellkamp, AS | 1 |
| Williams, JW | 1 |
| Califf, RM | 1 |
| Simel, DL | 1 |
| Williams, RG | 1 |
| Eccles, R | 1 |
| Otten, FW | 1 |
| Grote, JJ | 1 |
| Benammar-Englmaier, M | 1 |
| Hallermeier, JK | 1 |
| Englmaier, B | 1 |
| Finsnes, KA | 1 |
| Albegger, K | 1 |
| Huber, EG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does Nasal Decongestion Improve Obstructive Sleep Apnea ?[NCT00630474] | Phase 4 | 12 participants (Actual) | Interventional | 2004-01-31 | Completed | ||
| A Proof of Concept Study to Evaluate if Concomitant Topical Intranasal Steroid Prevents Tolerance and Rebound Congestion Due to Regular Oxymetazoline in Persistent Allergic Rhinitis.[NCT00846326] | Phase 4 | 0 participants (Actual) | Interventional | Withdrawn (stopped due to The suppliers were unable to provide the investigational medicinal product (IMP)) | |||
| A Proof of Concept Study to Evaluate Differential Tachyphylaxis of Alpha 1 and Alpha 2 Adrenoreceptor Mediated Decongestant Response to Oxymetazoline and Its Acute Reversal by Corticosteroid in Healthy Volunteers[NCT00487032] | Phase 4 | 19 participants (Actual) | Interventional | 2008-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for xylometazoline and Rhinitis
| Article | Year |
|---|---|
[Inflammatory diseases of the nose and nasal sinuses in children].
Topics: Acupuncture Therapy; Administration, Topical; Bacterial Infections; Child; Child, Preschool; Enzyme- | 1985 |
16 trials available for xylometazoline and Rhinitis
| Article | Year |
|---|---|
Dexpanthenol: An Overview of its Contribution to Symptom Relief in Acute Rhinitis Treated with Decongestant Nasal Sprays.
Topics: Administration, Intranasal; Adult; Aerosols; Double-Blind Method; Drug Therapy, Combination; Female; | 2017 |
Comparison of nasal hyperosmolar xylitol and xylometazoline solutions on quality of life in patients with inferior turbinate hypertrophy secondary to nonallergic rhinitis.
Topics: Adolescent; Adult; Female; Humans; Hypertrophy; Imidazoles; Male; Nasal Obstruction; Pharmaceutical | 2014 |
The use of large volume low pressure nasal saline with fluticasone propionate for the treatment of pediatric acute rhinosinusitis.
Topics: Acute Disease; Adolescent; Amoxicillin-Potassium Clavulanate Combination; Androstadienes; Anti-Infla | 2014 |
Does nasal decongestion improve obstructive sleep apnea?
Topics: Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Humans; Imidazoles; Male; Middle A | 2008 |
[Advance in therapy of acute rhinitis--comparison of efficacy and safety of xylometazoline in combination xylometazoline-dexpanthenol in patients with acute rhinitis].
Topics: Acute Disease; Administration, Intranasal; Adult; Double-Blind Method; Drug Combinations; Female; Hu | 2003 |
[Tolerance and effectiveness of oxymetazoline and xylometazoline in treatment of acute rhinitis].
Topics: Acute Disease; Administration, Intranasal; Adult; Aerosols; Benzalkonium Compounds; Common Cold; Dou | 2003 |
[Treatment of inflammatory diseases of the upper respiratory tract -- comparison of a homeopathic complex remedy with xylometazoline].
Topics: Adult; Cohort Studies; Euphorbia; Female; Homeopathy; Humans; Imidazoles; Male; Nasal Decongestants; | 2005 |
The value of Ems Mineral Salts in the treatment of rhinosinusitis in children. Prospective study on the efficacy of mineral salts versus xylometazoline in the topical nasal treatment of children.
Topics: Administration, Intranasal; Child; Child, Preschool; Double-Blind Method; Female; Humans; Imidazoles | 2005 |
[Xylometazoline (Otrivin) in acute rhinitis. A comparative study between pipette- and metered-dose aerosol applications].
Topics: Acute Disease; Administration, Intranasal; Adolescent; Adrenergic alpha-Agonists; Adult; Aerosols; C | 1984 |
A comparative preference study between xylometazoline nasal dose spray (Otrivin) and oxymetazoline single-dose pipettes (Nezeril).
Topics: Adult; Clinical Trials as Topic; Female; Humans; Imidazoles; Male; Nasal Decongestants; Oxymetazolin | 1983 |
[Comparison between xylometazoline in a dosage spray and oxymetazoline in one dose pipettes].
Topics: Adult; Aerosols; Clinical Trials as Topic; Female; Humans; Imidazoles; Male; Middle Aged; Oxymetazol | 1983 |
Relative bioavailability of nicotine from a nasal spray in infectious rhinitis and after use of a topical decongestant.
Topics: Administration, Intranasal; Adult; Biological Availability; Common Cold; Cross-Over Studies; Drug In | 1995 |
Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity.
Topics: Administration, Intranasal; Adult; Benzalkonium Compounds; Double-Blind Method; Drug Tolerance; Fema | 1996 |
Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity.
Topics: Administration, Intranasal; Adult; Benzalkonium Compounds; Double-Blind Method; Drug Tolerance; Fema | 1996 |
Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity.
Topics: Administration, Intranasal; Adult; Benzalkonium Compounds; Double-Blind Method; Drug Tolerance; Fema | 1996 |
Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity.
Topics: Administration, Intranasal; Adult; Benzalkonium Compounds; Double-Blind Method; Drug Tolerance; Fema | 1996 |
[Improving wound healing after nose surgery by combined administration of xylometazoline and dexpanthenol].
Topics: Adrenergic alpha-Agonists; Adult; Aerosols; Drug Therapy, Combination; Female; Humans; Imidazoles; M | 2000 |
Comparison of cefuroxime with or without intranasal fluticasone for the treatment of rhinosinusitis. The CAFFS Trial: a randomized controlled trial.
Topics: Acute Disease; Administration, Intranasal; Adult; Androstadienes; Anti-Inflammatory Agents; Cefuroxi | 2001 |
Otitis media with effusion and chronic upper respiratory tract infection in children: a randomized, placebo-controlled clinical study.
Topics: Amoxicillin; Child; Child, Preschool; Chronic Disease; Combined Modality Therapy; Drainage; Female; | 1990 |
19 other studies available for xylometazoline and Rhinitis
| Article | Year |
|---|---|
[Nasal toilet in infants with rhinitis: nasal passage crucial, so treat with xylometazoline].
Topics: Bathroom Equipment; Child; Child, Preschool; Humans; Imidazoles; Infant; Infant, Newborn; Nasal Deco | 2022 |
Recurrent thunderclap headaches from reversible cerebral vasoconstriction syndrome associated with duloxetine, xylometazoline and rhinitis medicamentosa.
Topics: Computed Tomography Angiography; Duloxetine Hydrochloride; Female; Headache Disorders, Primary; Huma | 2020 |
Rhinosinusitis associated with post-dental extraction chronic oroantral fistula: outcomes of non-surgical management comprising antibiotics and local decongestion therapy.
Topics: Administration, Topical; Adult; Aged; Anesthetics, Local; Anti-Bacterial Agents; Chronic Disease; Fe | 2016 |
Xylometazoline abuse induced ischemic stroke in a young adult.
Topics: Adult; Brain Ischemia; Humans; Imidazoles; Male; Nasal Decongestants; Rhinitis; Stroke; Substance-Re | 2011 |
["Of snakes and crocodiles": central side effects of nose drops and facts about rhinitis medicamentosa].
Topics: Administration, Intranasal; Adult; Child, Preschool; Drug Combinations; Female; Hallucinations; Huma | 2011 |
Septoplasty and decongestant improve distribution of nasal spray.
Topics: Adult; Female; Humans; Imidazoles; Male; Methylene Blue; Middle Aged; Nasal Decongestants; Nasal Sep | 2011 |
[Uncontrolled and controlled evaluation of a new medication for decongestion of the nasal mucosa].
Topics: Humans; Imidazoles; Nasal Mucosa; Nasal Polyps; Rhinitis; Sinusitis | 1962 |
[OBJECTIVE TRIAL OF THE MUCOSAL-SWELLING EFFECT OF XYLOMETAZOLINE].
Topics: Edema; Humans; Imidazoles; Mucous Membrane; Nasal Mucosa; Rhinitis; Sympathomimetics | 1964 |
AN OBJECTIVE INVESTIGATION OF THE DECONGESTIVE EFFECT OF XYLOMETAZOLINE.
Topics: Drug Therapy; Ephedrine; Humans; Imidazoles; Nasal Decongestants; Nose; Rhinitis; Vasoconstrictor Ag | 1964 |
[Ultrastructural changes in human nasal mucosa in rhinitis medicamentosa].
Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Capillary Permeability; Chronic Disease; Dose | 2006 |
Variability in nasal resistance measurements.
Topics: Air Pollutants; Airway Obstruction; Airway Resistance; Computers; Humans; Imidazoles; Manometry; Nas | 1980 |
Treatment with xylometazoline (Otrivin) nosedrops over a six-week period.
Topics: Adult; Airway Resistance; Female; Humans; Imidazoles; Male; Middle Aged; Nasal Decongestants; Rhinit | 1981 |
Treatment with xylometazoline (Otrivin) nosedrops over a six-week period.
Topics: Adult; Airway Resistance; Female; Humans; Imidazoles; Male; Middle Aged; Nasal Decongestants; Rhinit | 1981 |
Treatment with xylometazoline (Otrivin) nosedrops over a six-week period.
Topics: Adult; Airway Resistance; Female; Humans; Imidazoles; Male; Middle Aged; Nasal Decongestants; Rhinit | 1981 |
Treatment with xylometazoline (Otrivin) nosedrops over a six-week period.
Topics: Adult; Airway Resistance; Female; Humans; Imidazoles; Male; Middle Aged; Nasal Decongestants; Rhinit | 1981 |
[Long-term treatment with nose drops containing xylometazoline].
Topics: Administration, Intranasal; Adult; Female; Humans; Imidazoles; Male; Middle Aged; Rhinitis | 1981 |
Sustained use of xylometazoline nasal spray shortens the decongestive response and induces rebound swelling.
Topics: Adolescent; Adult; Aerosols; Female; Humans; Imidazoles; Male; Nasal Decongestants; Nasal Mucosa; Rh | 1995 |
[Rhinitis medicamentosa, an increasing problem. Do nose drops adversely affect bacterial infections?].
Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Humans; Imidazoles; Oxymetazoline; Rhinitis | 1994 |
The impact of over-the-counter availability of nasal sprays on sales, prescribing, and physician visits.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Prescriptions; Female; Health Expenditures; H | 1999 |
Nasal airflow asymmetry and the effects of a topical nasal decongestant.
Topics: Acute Disease; Adult; Airway Resistance; Common Cold; Humans; Imidazoles; Nasal Cavity; Nasal Decong | 1992 |
[Alpha-mimetic effects on nasal mucosa in magnetic resonance tomography].
Topics: Administration, Intranasal; Humans; Imidazoles; Magnetic Resonance Imaging; Nasal Decongestants; Nas | 1990 |
[Rhinitis medicamentosa].
Topics: Adult; Aged; Humans; Imidazoles; Male; Nasal Decongestants; Rhinitis | 1987 |