xylometazoline has been researched along with Nasal Obstruction in 27 studies
xylometazoline: RN given refers to parent cpd; structure
Nasal Obstruction: Any hindrance to the passage of air into and out of the nose. The obstruction may be unilateral or bilateral, and may involve any part of the NASAL CAVITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute Rhinitis is based on an inflammation of the nasal mucous membrane with nasal discharge and obstruction." | 6.71 | [Advance in therapy of acute rhinitis--comparison of efficacy and safety of xylometazoline in combination xylometazoline-dexpanthenol in patients with acute rhinitis]. ( Dethlefsen, U; Kehrl, W; Sonnemann, U, 2003) |
| " The risk of severe side effects with xylometazoline in young children is low if the dosage is adequate." | 5.72 | [Nasal toilet in infants with rhinitis: nasal passage crucial, so treat with xylometazoline]. ( Klok, T; Mensink, MHA; Videler, W; Wieringa, N, 2022) |
| "Nasal blockage is a common complaint in Family Practice." | 2.73 | Effects of an external nasal dilator strip (ENDS) compared to xylometazolin nasal spray. ( Dahle, S; Høyvoll, LR; Li, HS; Lunde, K; Steinsvåg, SK; Wentzel-Larsen, T, 2007) |
| "Acute Rhinitis is based on an inflammation of the nasal mucous membrane with nasal discharge and obstruction." | 2.71 | [Advance in therapy of acute rhinitis--comparison of efficacy and safety of xylometazoline in combination xylometazoline-dexpanthenol in patients with acute rhinitis]. ( Dethlefsen, U; Kehrl, W; Sonnemann, U, 2003) |
| " No clinically relevant adverse events were recorded." | 2.70 | Efficacy and safety of an oral formulation of cetirizine and prolonged-release pseudoephedrine versus xylometazoline nasal spray in nasal congestion. ( Berger, UE; Burtin, B; Horak, F; Marks, B; Stübner, UP; Toth, J, 2001) |
| "Nasal congestion due to the common cold may be exacerbated in small children because of their small nasal passages." | 2.69 | Nasal flow limitation in children. ( Beardsmore, CS; Pickering, DN, 1999) |
| " The risk of severe side effects with xylometazoline in young children is low if the dosage is adequate." | 1.72 | [Nasal toilet in infants with rhinitis: nasal passage crucial, so treat with xylometazoline]. ( Klok, T; Mensink, MHA; Videler, W; Wieringa, N, 2022) |
| "Xylometazoline hydrochloride was applied in each nasal cavity to minimize effects of mucosal variation and the nasal cavity was examined with rhinoscopy." | 1.37 | Can we always trust rhinomanometry? ( Cervin, A; Jessen, M; Thulesius, HL, 2011) |
| "Nasal obstruction is a very common problem associated with common cold and topical nasal decongestant sprays are effective symptomatic treatments causing a decrease in nasal airway resistance (NAR)." | 1.37 | Paradoxical increase in nasal airway resistance following a topical nasal decongestant spray. ( Doddi, NM; Eccles, R, 2011) |
| "Nasal obstruction is caused by rebound swelling when the decongestive effect has disappeared." | 1.33 | [Ultrastructural changes in human nasal mucosa in rhinitis medicamentosa]. ( Bloching, M; Holzhausen, HJ; Knipping, S; Riederer, A, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (33.33) | 18.2507 |
| 2000's | 6 (22.22) | 29.6817 |
| 2010's | 11 (40.74) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Mensink, MHA | 1 |
| Wieringa, N | 1 |
| Videler, W | 1 |
| Klok, T | 1 |
| Thorstensen, WM | 1 |
| Sue-Chu, M | 1 |
| Bugten, V | 1 |
| Steinsvåg, SK | 2 |
| Zicari, AM | 2 |
| Rugiano, A | 2 |
| Ragusa, G | 2 |
| Savastano, V | 1 |
| Bertin, S | 1 |
| Vittori, T | 1 |
| Duse, M | 2 |
| Cingi, C | 1 |
| Birdane, L | 1 |
| Ural, A | 1 |
| Oghan, F | 1 |
| Bal, C | 1 |
| Thulesius, HL | 2 |
| Cervin, A | 2 |
| Jessen, M | 3 |
| Salihoglu, M | 1 |
| Cekin, E | 1 |
| Altundag, A | 1 |
| Cesmeci, E | 1 |
| Tahamiler, R | 1 |
| Alimoglu, Y | 1 |
| Canakcioglu, S | 1 |
| Vogt, K | 1 |
| Wernecke, KD | 1 |
| Behrbohm, H | 1 |
| Gubisch, W | 1 |
| Argale, M | 1 |
| Volk, GF | 1 |
| Pantel, M | 1 |
| Guntinas-Lichius, O | 1 |
| Wittekindt, C | 1 |
| Doddi, NM | 1 |
| Eccles, R | 1 |
| Magliulo, G | 1 |
| Celani, C | 1 |
| Carbone, MP | 1 |
| Occasi, F | 1 |
| Kehrl, W | 1 |
| Sonnemann, U | 2 |
| Dethlefsen, U | 2 |
| Michel, O | 1 |
| Essers, S | 1 |
| Heppt, WJ | 1 |
| Johannssen, V | 1 |
| Reuter, W | 1 |
| Hommel, G | 1 |
| Knipping, S | 1 |
| Holzhausen, HJ | 1 |
| Riederer, A | 1 |
| Bloching, M | 1 |
| Høyvoll, LR | 1 |
| Lunde, K | 1 |
| Li, HS | 1 |
| Dahle, S | 1 |
| Wentzel-Larsen, T | 1 |
| Tesche, S | 1 |
| Metternich, F | 1 |
| Engelke, JC | 1 |
| Kunkel, M | 3 |
| Hochban, W | 1 |
| Porter, MJ | 1 |
| Williamson, I | 1 |
| Kerridge, D | 1 |
| Maw, R | 1 |
| Graf, P | 1 |
| Ivarsson, A | 1 |
| Malm, L | 1 |
| Wålinder, R | 1 |
| Norbäck, D | 1 |
| Wieslander, G | 1 |
| Smedje, G | 1 |
| Erwall, C | 1 |
| Wahlmann, U | 2 |
| Wagner, W | 2 |
| Pickering, DN | 1 |
| Beardsmore, CS | 1 |
| Stübner, UP | 1 |
| Toth, J | 1 |
| Marks, B | 1 |
| Berger, UE | 1 |
| Burtin, B | 1 |
| Horak, F | 1 |
| Månsson, I | 1 |
| Fredriksson, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Proof of Concept Study to Evaluate if Concomitant Topical Intranasal Steroid Prevents Tolerance and Rebound Congestion Due to Regular Oxymetazoline in Persistent Allergic Rhinitis.[NCT00846326] | Phase 4 | 0 participants (Actual) | Interventional | Withdrawn (stopped due to The suppliers were unable to provide the investigational medicinal product (IMP)) | |||
| A Proof of Concept Study to Evaluate Differential Tachyphylaxis of Alpha 1 and Alpha 2 Adrenoreceptor Mediated Decongestant Response to Oxymetazoline and Its Acute Reversal by Corticosteroid in Healthy Volunteers[NCT00487032] | Phase 4 | 19 participants (Actual) | Interventional | 2008-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 trials available for xylometazoline and Nasal Obstruction
| Article | Year |
|---|---|
Comparison of nasal hyperosmolar xylitol and xylometazoline solutions on quality of life in patients with inferior turbinate hypertrophy secondary to nonallergic rhinitis.
Topics: Adolescent; Adult; Female; Humans; Hypertrophy; Imidazoles; Male; Nasal Obstruction; Pharmaceutical | 2014 |
Prognostic value of anterior rhinomanometry in diode laser turbinoplasty.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Female; Humans; Hyperplasia; Imidazoles; Lasers | 2010 |
The role of rhinomanometry after nasal decongestant test in the assessment of adenoid hypertrophy in children.
Topics: Adenoids; Age Factors; Child; Endoscopy; Female; Humans; Hypertrophy; Imidazoles; Male; Nasal Decong | 2012 |
[Advance in therapy of acute rhinitis--comparison of efficacy and safety of xylometazoline in combination xylometazoline-dexpanthenol in patients with acute rhinitis].
Topics: Acute Disease; Administration, Intranasal; Adult; Double-Blind Method; Drug Combinations; Female; Hu | 2003 |
The value of Ems Mineral Salts in the treatment of rhinosinusitis in children. Prospective study on the efficacy of mineral salts versus xylometazoline in the topical nasal treatment of children.
Topics: Administration, Intranasal; Child; Child, Preschool; Double-Blind Method; Female; Humans; Imidazoles | 2005 |
Effects of an external nasal dilator strip (ENDS) compared to xylometazolin nasal spray.
Topics: Administration, Intranasal; Administration, Topical; Adult; Dilatation; Female; Humans; Imidazoles; | 2007 |
The value of herbal medicines in the treatment of acute non-purulent rhinosinusitis. Results of a double-blind, randomised, controlled trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Imidazoles; Male; Middl | 2008 |
Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity.
Topics: Administration, Intranasal; Adult; Benzalkonium Compounds; Double-Blind Method; Drug Tolerance; Fema | 1996 |
Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity.
Topics: Administration, Intranasal; Adult; Benzalkonium Compounds; Double-Blind Method; Drug Tolerance; Fema | 1996 |
Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity.
Topics: Administration, Intranasal; Adult; Benzalkonium Compounds; Double-Blind Method; Drug Tolerance; Fema | 1996 |
Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity.
Topics: Administration, Intranasal; Adult; Benzalkonium Compounds; Double-Blind Method; Drug Tolerance; Fema | 1996 |
Nasal flow limitation in children.
Topics: Administration, Intranasal; Adolescent; Airway Resistance; Child; Child, Preschool; Common Cold; Dil | 1999 |
Efficacy and safety of an oral formulation of cetirizine and prolonged-release pseudoephedrine versus xylometazoline nasal spray in nasal congestion.
Topics: Administration, Intranasal; Administration, Oral; Adult; Blood Pressure; Cetirizine; Cross-Over Stud | 2001 |
[Which nasal spray is preferred by patients?].
Topics: Adolescent; Adult; Aerosols; Aged; Child; Drug Evaluation; Female; Humans; Imidazoles; Male; Middle | 1991 |
16 other studies available for xylometazoline and Nasal Obstruction
| Article | Year |
|---|---|
[Nasal toilet in infants with rhinitis: nasal passage crucial, so treat with xylometazoline].
Topics: Bathroom Equipment; Child; Child, Preschool; Humans; Imidazoles; Infant; Infant, Newborn; Nasal Deco | 2022 |
Nasal flow, volumes, and minimal cross sectional areas in asthmatics.
Topics: Adult; Aged; Anthropometry; Asthma; Case-Control Studies; Female; Humans; Hypersensitivity; Imidazol | 2013 |
The evaluation of adenoid hypertrophy and obstruction grading based on rhinomanometry after nasal decongestant test in children.
Topics: Adenoids; Child; Endoscopy; Female; Fiber Optic Technology; Humans; Hypertrophy; Imidazoles; Male; N | 2013 |
Treatment with a topical glucocorticoid, budesonide, reduced the variability of rhinomanometric nasal airway resistance.
Topics: Airway Resistance; Budesonide; Glucocorticoids; Humans; Imidazoles; Nasal Cavity; Nasal Obstruction; | 2014 |
Examination versus subjective nasal obstruction in the evaluation of the nasal septal deviation.
Topics: Adult; Cohort Studies; Humans; Hypertrophy; Imidazoles; Male; Nasal Decongestants; Nasal Obstruction | 2014 |
The contribution of erectile elements to nasal patency: an examination with nasal sound analysis.
Topics: Adult; Endoscopy; Female; Humans; Hyperostosis; Imidazoles; Male; Nasal Decongestants; Nasal Obstruc | 2015 |
Four-phase rhinomanometry: a multicentric retrospective analysis of 36,563 clinical measurements.
Topics: Adult; Airway Resistance; Humans; Imidazoles; Nasal Decongestants; Nasal Obstruction; Nose; Pain Mea | 2016 |
Can we always trust rhinomanometry?
Topics: Adult; Female; Humans; Imidazoles; Male; Middle Aged; Nasal Decongestants; Nasal Obstruction; Reprod | 2011 |
Paradoxical increase in nasal airway resistance following a topical nasal decongestant spray.
Topics: Adult; Humans; Imidazoles; Male; Nasal Decongestants; Nasal Obstruction | 2011 |
[Ultrastructural changes in human nasal mucosa in rhinitis medicamentosa].
Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Capillary Permeability; Chronic Disease; Dose | 2006 |
Acoustic rhinometry: rationale and perspectives.
Topics: Acoustics; Equipment Design; Female; Humans; Imidazoles; Male; Mandible; Maxilla; Nasal Cavity; Nasa | 1994 |
Manometric rhinometry.
Topics: Adult; Female; Humans; Imidazoles; Male; Manometry; Nasal Decongestants; Nasal Obstruction; Paranasa | 1995 |
Nasal airway resistance after decongestion with a nasal spray or a bellows device.
Topics: Administration, Intranasal; Adult; Airway Resistance; Female; Humans; Imidazoles; Male; Manometry; M | 1996 |
Nasal congestion in relation to low air exchange rate in schools. Evaluation by acoustic rhinometry.
Topics: Acoustic Stimulation; Air Pollution, Indoor; Edema; Humans; Imidazoles; Manometry; Nasal Decongestan | 1997 |
Nasal airway in cleft-palate patients: acoustic rhinometric data.
Topics: Acoustics; Adolescent; Adult; Child; Cleft Lip; Cleft Palate; Follow-Up Studies; Humans; Hypertrophy | 1997 |
Acoustic airway profiles in unilateral cleft palate patients.
Topics: Acoustics; Adolescent; Adult; Biophysics; Cleft Palate; Humans; Imidazoles; Nasal Cavity; Nasal Deco | 1999 |