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xylometazoline and Common Cold

xylometazoline has been researched along with Common Cold in 12 studies

xylometazoline: RN given refers to parent cpd; structure

Common Cold: A catarrhal disorder of the upper respiratory tract, which may be viral or a mixed infection. It generally involves a runny nose, nasal congestion, and sneezing.

Research Excerpts

ExcerptRelevanceReference
"This randomised, double-blind, multi-centered, verum-controlled tolerance study confirmed that the local sympathomimetics oxymetazoline and xylometazoline are well tolerated in the treatment of acute rhinitis."9.10[Tolerance and effectiveness of oxymetazoline and xylometazoline in treatment of acute rhinitis]. ( Dorn, M; Hofmann, W; Knick, E, 2003)
"The relative bioavailability of nicotine from a nasal spray was assessed in 15 smokers suffering a common cold and rhinitis according to generally accepted criteria."9.08Relative bioavailability of nicotine from a nasal spray in infectious rhinitis and after use of a topical decongestant. ( Andersson, M; Lunell, E; Molander, L, 1995)
"To review the published clinical efficacy and safety of xylometazoline alone and in combination in the management of nasal congestion in patients with common cold."8.86Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common cold. ( Chen, SC; Eccles, R; Martensson, K, 2010)
"This review assesses two widely used intranasal treatments for nasal congestion and rhinorrhea in the common cold: xylometazoline hydrochloride and ipratropium bromide."8.85Efficacy and safety of intranasal xylometazoline and ipratropium in patients with common cold. ( Chen, S; Eccles, R; Graf, P, 2009)
"Combination of xylometazoline and ipratropium in a nasal spray provides fast, effective symptomatic relief of nasal congestion and rhinorrhea in adults with common cold."7.75OTC use of a topical nasal spray solution containing xylometazoline plus ipratropium in patients with common cold. ( Chen, S; Jakobsen, HB; Norgren-Holst, E; Strandell, B; Tran, N, 2009)
"This randomised, double-blind, multi-centered, verum-controlled tolerance study confirmed that the local sympathomimetics oxymetazoline and xylometazoline are well tolerated in the treatment of acute rhinitis."5.10[Tolerance and effectiveness of oxymetazoline and xylometazoline in treatment of acute rhinitis]. ( Dorn, M; Hofmann, W; Knick, E, 2003)
"The relative bioavailability of nicotine from a nasal spray was assessed in 15 smokers suffering a common cold and rhinitis according to generally accepted criteria."5.08Relative bioavailability of nicotine from a nasal spray in infectious rhinitis and after use of a topical decongestant. ( Andersson, M; Lunell, E; Molander, L, 1995)
"Between november 1993 and july 1995 60 patients with a common cold underwent randomized and double-blind testing of 3 commercial nasal sprays-benzydamine, xylometazoline combined with the secretolytic S-carboxymethylcysteine, and phenylephrine combined with the antihistaminic dimethindene maleate."5.08[Decongestant nasal spray. Results of a rhinomanometric double-blind study]. ( Maranta, CA; Simmen, D, 1996)
"To review the published clinical efficacy and safety of xylometazoline alone and in combination in the management of nasal congestion in patients with common cold."4.86Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common cold. ( Chen, SC; Eccles, R; Martensson, K, 2010)
"This review assesses two widely used intranasal treatments for nasal congestion and rhinorrhea in the common cold: xylometazoline hydrochloride and ipratropium bromide."4.85Efficacy and safety of intranasal xylometazoline and ipratropium in patients with common cold. ( Chen, S; Eccles, R; Graf, P, 2009)
"Combination of xylometazoline and ipratropium in a nasal spray provides fast, effective symptomatic relief of nasal congestion and rhinorrhea in adults with common cold."3.75OTC use of a topical nasal spray solution containing xylometazoline plus ipratropium in patients with common cold. ( Chen, S; Jakobsen, HB; Norgren-Holst, E; Strandell, B; Tran, N, 2009)
" The aims of this study were to determine the degree of this asymmetry in healthy subjects and those with acute rhinitis associated with common cold, and to investigate how the administration of a topical nasal decongestant (xylometazoline) influenced the asymmetry in NAR."3.68Nasal airflow asymmetry and the effects of a topical nasal decongestant. ( Eccles, R; Williams, RG, 1992)
"Nasal congestion due to the common cold may be exacerbated in small children because of their small nasal passages."2.69Nasal flow limitation in children. ( Beardsmore, CS; Pickering, DN, 1999)
"Many treatments for the common cold exist and are sold over-the-counter."2.53Nasal decongestants in monotherapy for the common cold. ( De Sutter, AI; Deckx, L; Guo, L; Mir, NA; van Driel, ML, 2016)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's4 (33.33)18.2507
2000's3 (25.00)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deckx, L1
De Sutter, AI1
Guo, L1
Mir, NA1
van Driel, ML1
Graf, P1
Eccles, R3
Chen, S2
Strandell, B1
Norgren-Holst, E1
Tran, N1
Jakobsen, HB1
Martensson, K1
Chen, SC1
SONNTAG, HP1
Dorn, M1
Hofmann, W1
Knick, E1
Hamilton, LH1
Lunell, E1
Molander, L1
Andersson, M1
Maranta, CA1
Simmen, D1
Pickering, DN1
Beardsmore, CS1
Williams, RG1
Zalzstein, E1
Lifshitz, M1

Reviews

3 reviews available for xylometazoline and Common Cold

ArticleYear
Nasal decongestants in monotherapy for the common cold.
    The Cochrane database of systematic reviews, 2016, Oct-17, Volume: 10

    Topics: Administration, Intranasal; Adult; Child; Common Cold; Humans; Imidazoles; Nasal Decongestants; Oxym

2016
Efficacy and safety of intranasal xylometazoline and ipratropium in patients with common cold.
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:5

    Topics: Administration, Intranasal; Animals; Clinical Trials as Topic; Common Cold; Drug Therapy, Combinatio

2009
Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common cold.
    Current medical research and opinion, 2010, Volume: 26, Issue:4

    Topics: Administration, Intranasal; Bronchodilator Agents; Common Cold; Drug Therapy, Combination; Drug-Rela

2010

Trials

4 trials available for xylometazoline and Common Cold

ArticleYear
[Tolerance and effectiveness of oxymetazoline and xylometazoline in treatment of acute rhinitis].
    HNO, 2003, Volume: 51, Issue:10

    Topics: Acute Disease; Administration, Intranasal; Adult; Aerosols; Benzalkonium Compounds; Common Cold; Dou

2003
Relative bioavailability of nicotine from a nasal spray in infectious rhinitis and after use of a topical decongestant.
    European journal of clinical pharmacology, 1995, Volume: 48, Issue:1

    Topics: Administration, Intranasal; Adult; Biological Availability; Common Cold; Cross-Over Studies; Drug In

1995
[Decongestant nasal spray. Results of a rhinomanometric double-blind study].
    Schweizerische medizinische Wochenschrift, 1996, Nov-02, Volume: 126, Issue:44

    Topics: Administration, Intranasal; Adolescent; Adult; Airway Resistance; Anti-Infective Agents, Local; Carb

1996
Nasal flow limitation in children.
    Pediatric pulmonology, 1999, Volume: 27, Issue:1

    Topics: Administration, Intranasal; Adolescent; Airway Resistance; Child; Child, Preschool; Common Cold; Dil

1999

Other Studies

5 other studies available for xylometazoline and Common Cold

ArticleYear
OTC use of a topical nasal spray solution containing xylometazoline plus ipratropium in patients with common cold.
    International journal of clinical pharmacology and therapeutics, 2009, Volume: 47, Issue:12

    Topics: Administration, Intranasal; Adolescent; Adult; Cholinergic Antagonists; Common Cold; Drug Therapy, C

2009
[Experiences with otriven].
    Deutsches medizinisches Journal, 1959, Nov-20, Volume: 10

    Topics: Common Cold; Hypothermia, Induced; Imidazoles; Sympathomimetics

1959
Effect of xylometazoline nasal spray on nasal conductance in subjects with coryza.
    The Journal of otolaryngology, 1981, Volume: 10, Issue:2

    Topics: Administration, Intranasal; Adolescent; Adult; Airway Resistance; Common Cold; Female; Humans; Imida

1981
Nasal airflow asymmetry and the effects of a topical nasal decongestant.
    Rhinology, 1992, Volume: 30, Issue:4

    Topics: Acute Disease; Adult; Airway Resistance; Common Cold; Humans; Imidazoles; Nasal Cavity; Nasal Decong

1992
[Nasal drops as a cause of severe drug intoxication in infancy].
    Harefuah, 1985, Volume: 109, Issue:7-8

    Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Common Cold; Humans; Imidazoles; Infant, Newb

1985