xylazine has been researched along with Substance-Related Disorders in 11 studies
Xylazine: An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
xylazine : A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.
Substance-Related Disorders: Disorders related to substance use or abuse.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Xylazine alone has proven harmful to humans and even more when it is combined with drugs of abuse." | 2.50 | Xylazine intoxication in humans and its importance as an emerging adulterant in abused drugs: A comprehensive review of the literature. ( Chavez-Arias, C; Díaz-Alcalá, JE; Martínez, MA; Ruiz-Colón, K, 2014) |
| "The National Programme on Substance Abuse Deaths (NPSAD) receives reports on drug-related deaths from coroners In England, Wales and Northern Ireland on a voluntary basis." | 1.91 | The first drug-related death associated with xylazine use in the UK and Europe. ( Copeland, CS; Duffy, J; Lawson, AJ; Mellor, A; Rock, KL; Treble, R, 2023) |
| "Xylazine is an emerging adulterant with fentanyl in fatal drug intoxications, which has public health, safety, and criminal investigative implications." | 1.62 | Xylazine, a Veterinary Tranquilizer, Detected in 42 Accidental Fentanyl Intoxication Deaths. ( DeJoseph, ME; Gill, JR; Nunez, J, 2021) |
| "Xylazine has structural similarity to the phenothiazines and pharmacological activity similar to clonidine." | 1.27 | Human overdose with the veterinary tranquilizer xylazine. ( Grimes, MJ; Hall, AH; Honea, BN; Rumack, BH; Spoerke, DG, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Deutsch, SA | 1 |
| De Jong, AR | 1 |
| Rock, KL | 1 |
| Lawson, AJ | 1 |
| Duffy, J | 1 |
| Mellor, A | 1 |
| Treble, R | 1 |
| Copeland, CS | 1 |
| Nunez, J | 1 |
| DeJoseph, ME | 1 |
| Gill, JR | 1 |
| Ruiz-Colón, K | 1 |
| Chavez-Arias, C | 1 |
| Díaz-Alcalá, JE | 1 |
| Martínez, MA | 1 |
| Reyes, JC | 1 |
| Negrón, JL | 1 |
| Colón, HM | 1 |
| Padilla, AM | 1 |
| Millán, MY | 1 |
| Matos, TD | 1 |
| Robles, RR | 1 |
| Elejalde, JI | 1 |
| Louis, CJ | 1 |
| Elcuaz, R | 1 |
| Pinillos, MA | 1 |
| Liu, CM | 1 |
| Chiu, MJ | 1 |
| Fang, CC | 1 |
| Chen, WJ | 1 |
| Rodríguez, N | 1 |
| Vargas Vidot, J | 1 |
| Panelli, J | 1 |
| Colón, H | 1 |
| Ritchie, B | 1 |
| Yamamura, Y | 1 |
| Capraro, AJ | 1 |
| Wiley, JF | 1 |
| Tucker, JR | 1 |
| López Briz, E | 1 |
| Barreda Aznar, A | 1 |
| Guevara Serrano, J | 1 |
| Spoerke, DG | 1 |
| Hall, AH | 1 |
| Grimes, MJ | 1 |
| Honea, BN | 1 |
| Rumack, BH | 1 |
2 reviews available for xylazine and Substance-Related Disorders
| Article | Year |
|---|---|
Xylazine intoxication in humans and its importance as an emerging adulterant in abused drugs: A comprehensive review of the literature.
Topics: Bradycardia; Chromatography; Drug Contamination; Forensic Toxicology; Humans; Hyperglycemia; Hypnoti | 2014 |
Severe intoxication from xylazine inhalation.
Topics: Administration, Inhalation; Adolescent; Adrenergic alpha-Agonists; Coma; Drug Overdose; Humans; Male | 2001 |
9 other studies available for xylazine and Substance-Related Disorders
| Article | Year |
|---|---|
Xylazine Complicating Opioid Ingestions in Young Children.
Topics: Adult; Analgesics, Opioid; Child; Child, Preschool; Drug Overdose; Humans; Naloxone; Respiratory Ins | 2023 |
The first drug-related death associated with xylazine use in the UK and Europe.
Topics: Adult; Analgesics, Opioid; Drug Overdose; Europe; Fentanyl; Heroin; Humans; Illicit Drugs; Male; Pha | 2023 |
Xylazine, a Veterinary Tranquilizer, Detected in 42 Accidental Fentanyl Intoxication Deaths.
Topics: Accidents; Adult; Analgesics, Opioid; Chromatography, Liquid; Connecticut; Coroners and Medical Exam | 2021 |
The emerging of xylazine as a new drug of abuse and its health consequences among drug users in Puerto Rico.
Topics: Administration, Inhalation; Adult; Cocaine; Cross-Sectional Studies; Drug Combinations; Female; Focu | 2012 |
Drug abuse with inhalated xylazine.
Topics: Adolescent; Drug Overdose; Humans; Male; Substance-Related Disorders; Xylazine | 2003 |
Xylazine abuse: a rare cause of syncope.
Topics: Adrenergic alpha-Agonists; Adult; Humans; Hypotension, Orthostatic; Male; Substance-Related Disorder | 2007 |
GC-MS confirmation of xylazine (Rompun), a veterinary sedative, in exchanged needles.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adrenergic alpha-Agonists; Adult; Female; Gas Chroma | 2008 |
[Veterinary drugs: a new source of drug abuse?].
Topics: Buprenorphine; Humans; Substance-Related Disorders; Veterinary Medicine; Xylazine | 1991 |
Human overdose with the veterinary tranquilizer xylazine.
Topics: Adult; Blood Pressure; Central Nervous System; Female; Heart Rate; Humans; Injections, Intramuscular | 1986 |