xylazine has been researched along with Intraocular Pressure in 22 studies
Xylazine: An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
xylazine : A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effects of intramuscular (IM) administration of medetomidine and xylazine on intraocular pressure (IOP) and pupil size in normal dogs." | 9.20 | Effects of medetomidine and xylazine on intraocular pressure and pupil size in healthy Beagle dogs. ( Furukawa, T; Higashi, K; Iguchi, A; Kanda, T; Kaya, M; Kuramoto, T; Nomura, H; Yamamoto, R; Yoshioka, C, 2015) |
| "Amplitudes of electroretinograms (ERG) are enhanced during acute, moderate elevation of intraocular pressure (IOP) in rats anaesthetised with isoflurane." | 7.85 | Isoflurane and ketamine:xylazine differentially affect intraocular pressure-associated scotopic threshold responses in Sprague-Dawley rats. ( Bizheva, K; Choh, V; Feng, Y; Gurdita, A; Joos, KM; McCulloch, DL; Tan, B, 2017) |
| "To determine the effects of intravenous and intramuscular xylazine-ketamine on intraocular pressure (IOP) in laboratory rabbits, 10 New Zealand white rabbits received xylazine (0." | 7.79 | Effect of sedation with xylazine and ketamine on intraocular pressure in New Zealand white rabbits. ( Gum, GG; Holve, DL; Pritt, SL, 2013) |
| "Melatonin injected into the vortex vein of a rabbit eye produced an increase in intraocular pressure (IOP) which lasted for up to 5 h." | 7.68 | Effects of melatonin and haloperidol given via vortex vein on the intraocular pressure. ( Chiou, GC; Li, BH; Rohde, BH, 1993) |
| "Intraocular pressure was measured with a MacKay-Marg tonometer in eight horses following auriculopalpebral nerve block and topical application of lignocaine." | 5.27 | Effect of xylazine and ketamine on intraocular pressure in horses. ( Colbern, GT; Martin, CL; Trim, CM, 1985) |
| "To compare the effects of both injectable anesthesia (ketamine/dexmedetomidine versus ketamine/xylazine) and inhalant anesthesia (isoflurane) on IOP using continuous, bilateral IOP telemetry in nonhuman primates (NHP)." | 3.91 | Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates. ( Downs, JC; Girkin, CA; Jasien, JV, 2019) |
| "Administration of ketamine/xylazine anesthesia for 120 min did not alter outflow facility or lessen the effect of latanoprost on outflow facility in mice as determined by a new analysis system." | 3.76 | Duration of anesthesia affects intraocular pressure, but not outflow facility in mice. ( Camras, CB; Camras, LJ; Fan, S; Liu, H; Sufficool, KE; Toris, CB, 2010) |
| "Melatonin injected into the vortex vein of a rabbit eye produced an increase in intraocular pressure (IOP) which lasted for up to 5 h." | 3.68 | Effects of melatonin and haloperidol given via vortex vein on the intraocular pressure. ( Chiou, GC; Li, BH; Rohde, BH, 1993) |
| " Acepromazine, ketamine, xylazine, droperidol-fentamyl, and combinations of these drugs were evaluated for effects on blood pressure, intraocular pressure, and restraint of the dog for 4 minutes of Schiotz tonography of each eye." | 3.65 | Tonography in the normal and glaucomatous beagle. ( Gelatt, KN; Gum, GG; Gwin, RM; Peiffer, RL, 1977) |
| "Senile glaucoma is a common ophthalmological disease in the elderly." | 1.72 | Explore the molecular mechanism of angle-closure glaucoma in elderly patients induced telomere shortening of retinal ganglion cells through oxidative stress. ( Chen, F; Xia, X; Yan, A; Zhou, J, 2022) |
| "Xylazine is an agent frequently used in combination with ketamine to anesthetize rabbits." | 1.27 | The ocular effects of xylazine in rabbits, cats, and monkeys. ( Burke, JA; Potter, DE, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 10 (45.45) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, J | 1 |
| Chen, F | 1 |
| Yan, A | 1 |
| Xia, X | 1 |
| Jasien, JV | 1 |
| Girkin, CA | 1 |
| Downs, JC | 1 |
| Joyner, RL | 1 |
| Liu, CC | 1 |
| Cremer, J | 1 |
| Carter, RT | 1 |
| Lewin, AC | 1 |
| Chae, JJ | 1 |
| Prausnitz, MR | 1 |
| Ethier, CR | 1 |
| Monk, CS | 1 |
| Brooks, DE | 1 |
| Granone, T | 1 |
| Garcia-Pereira, FL | 1 |
| Melesko, A | 1 |
| Plummer, CE | 1 |
| Choh, V | 1 |
| Gurdita, A | 1 |
| Tan, B | 1 |
| Feng, Y | 1 |
| Bizheva, K | 1 |
| McCulloch, DL | 1 |
| Joos, KM | 1 |
| Gandhi, JK | 1 |
| Roy Chowdhury, U | 1 |
| Manzar, Z | 1 |
| Buck, J | 1 |
| Levin, LR | 1 |
| Fautsch, MP | 1 |
| Marmorstein, AD | 1 |
| Holve, DL | 1 |
| Gum, GG | 3 |
| Pritt, SL | 1 |
| Kanda, T | 1 |
| Iguchi, A | 1 |
| Yoshioka, C | 1 |
| Nomura, H | 1 |
| Higashi, K | 1 |
| Kaya, M | 1 |
| Yamamoto, R | 1 |
| Kuramoto, T | 1 |
| Furukawa, T | 1 |
| Rajaei, SM | 1 |
| Mood, MA | 1 |
| Paryani, MR | 1 |
| Williams, DL | 1 |
| Camras, LJ | 1 |
| Sufficool, KE | 1 |
| Camras, CB | 1 |
| Fan, S | 2 |
| Liu, H | 1 |
| Toris, CB | 2 |
| Ding, C | 1 |
| Wang, P | 1 |
| Tian, N | 1 |
| Cone, FE | 1 |
| Steinhart, MR | 1 |
| Oglesby, EN | 1 |
| Kalesnykas, G | 1 |
| Pease, ME | 1 |
| Quigley, HA | 1 |
| Johnson, TV | 1 |
| van der Woerdt, A | 1 |
| Gilger, BC | 1 |
| Wilkie, DA | 1 |
| Strauch, SM | 1 |
| Rohde, BH | 1 |
| Li, BH | 1 |
| Chiou, GC | 1 |
| Ofri, R | 1 |
| Horowitz, I | 1 |
| Jacobson, S | 1 |
| Kass, PH | 1 |
| Jia, L | 1 |
| Cepurna, WO | 1 |
| Johnson, EC | 1 |
| Morrison, JC | 1 |
| Gelatt, KN | 2 |
| Gwin, RM | 1 |
| Peiffer, RL | 1 |
| McClure, JR | 1 |
| Manning, JP | 1 |
| Burke, JA | 1 |
| Potter, DE | 1 |
| Trim, CM | 1 |
| Colbern, GT | 1 |
| Martin, CL | 1 |
1 trial available for xylazine and Intraocular Pressure
| Article | Year |
|---|---|
Effects of medetomidine and xylazine on intraocular pressure and pupil size in healthy Beagle dogs.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Cross-Over Studies; Dogs; Dose-Response Relationship, | 2015 |
21 other studies available for xylazine and Intraocular Pressure
| Article | Year |
|---|---|
Explore the molecular mechanism of angle-closure glaucoma in elderly patients induced telomere shortening of retinal ganglion cells through oxidative stress.
Topics: Animals; beta-Galactosidase; Disease Models, Animal; Fluorescent Dyes; Glaucoma; Glaucoma, Angle-Clo | 2022 |
Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates.
Topics: Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Dexm | 2019 |
Intraocular pressure following four different intravenous sedation protocols in normal horses.
Topics: Animals; Butorphanol; Eye Diseases; Horse Diseases; Horses; Intraocular Pressure; Tonometry, Ocular; | 2021 |
Effects of General Anesthesia on Intraocular Pressure in Rabbits.
Topics: Anesthesia, General; Animals; Intraocular Pressure; Isoflurane; Rabbits; Tonometry, Ocular; Xylazine | 2021 |
Measurement of intraocular pressure in healthy anesthetized horses during hoisting.
Topics: Anesthesia; Animals; Elective Surgical Procedures; Horses; Intraocular Pressure; Ketamine; Moving an | 2017 |
Isoflurane and ketamine:xylazine differentially affect intraocular pressure-associated scotopic threshold responses in Sprague-Dawley rats.
Topics: Anesthetics, Combined; Anesthetics, Inhalation; Animals; Dark Adaptation; Electroretinography; Injec | 2017 |
Differential Intraocular Pressure Measurements by Tonometry and Direct Cannulation After Treatment with Soluble Adenylyl Cyclase Inhibitors.
Topics: Acepromazine; Adenylyl Cyclase Inhibitors; Anesthetics; Animals; Anterior Chamber; Catheterization; | 2017 |
Effect of sedation with xylazine and ketamine on intraocular pressure in New Zealand white rabbits.
Topics: Animals; Female; Hypnotics and Sedatives; Intraocular Pressure; Ketamine; Rabbits; Xylazine | 2013 |
Effects of diurnal variation and anesthetic agents on intraocular pressure in Syrian hamsters (Mesocricetus auratus).
Topics: Anesthetics; Animals; Circadian Rhythm; Diazepam; Drug Therapy, Combination; Female; Intraocular Pre | 2017 |
Duration of anesthesia affects intraocular pressure, but not outflow facility in mice.
Topics: Analgesics; Anesthesia; Anesthetics, Dissociative; Animals; Antihypertensive Agents; Aqueous Humor; | 2010 |
Effect of general anesthetics on IOP in elevated IOP mouse model.
Topics: Anesthesia, General; Anesthetics, Combined; Anesthetics, General; Animals; Behavior, Animal; Disease | 2011 |
The effects of anesthesia, mouse strain and age on intraocular pressure and an improved murine model of experimental glaucoma.
Topics: Acepromazine; Aging; Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Axons; | 2012 |
Rebound tonometry in conscious, conditioned mice avoids the acute and profound effects of anesthesia on intraocular pressure.
Topics: Anesthesia, General; Anesthetics, Combined; Animals; Cross-Over Studies; Ethanol; Intraocular Pressu | 2008 |
Effect of auriculopalpebral nerve block and intravenous administration of xylazine on intraocular pressure and corneal thickness in horses.
Topics: Animals; Cornea; Female; Horses; Injections, Intravenous; Intraocular Pressure; Male; Nerve Block; X | 1995 |
Effects of melatonin and haloperidol given via vortex vein on the intraocular pressure.
Topics: Analgesics; Animals; Ciliary Body; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Haloper | 1993 |
The effects of anesthesia and gender on intraocular pressure in lions (Panthera leo).
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Anesthesia; Animals; Animals, Zoo; Atropine; Femal | 1998 |
Effect of general anesthetics on IOP in rats with experimental aqueous outflow obstruction.
Topics: Acepromazine; Anesthetics, Combined; Anesthetics, General; Animals; Aqueous Humor; Intraocular Press | 2000 |
Tonography in the normal and glaucomatous beagle.
Topics: Acepromazine; Animals; Aqueous Humor; Atropine; Blood Pressure; Dog Diseases; Dogs; Droperidol; Drug | 1977 |
The effect of parenteral acepromazine and xylazine on intraocular pressure in the horse.
Topics: Acepromazine; Animals; Female; Horses; Intraocular Pressure; Male; Thiazines; Xylazine | 1976 |
The ocular effects of xylazine in rabbits, cats, and monkeys.
Topics: Animals; Cats; Cebus; Clonidine; Female; Intraocular Pressure; Male; Nictitating Membrane; Pupil; Ra | 1986 |
Effect of xylazine and ketamine on intraocular pressure in horses.
Topics: Animals; Horses; Intraocular Pressure; Ketamine; Male; Thiazines; Xylazine | 1985 |