xylazine has been researched along with Innate Inflammatory Response in 10 studies
Xylazine: An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
xylazine : A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We aimed to investigate the role of oxidative stress, renal inflammation, and apoptosis in the injury of the kidney tissue after ischemic reperfusion, and the protective effect of dose-dependent boric acid administration." | 7.96 | The Role of Oxidative Stress, Renal Inflammation, and Apoptosis in Post Ischemic Reperfusion Injury of Kidney Tissue: the Protective Effect of Dose-Dependent Boric Acid Administration. ( Donmez, DB; Hacioglu, C; Kanbak, G; Kar, F; Senturk, H, 2020) |
| " In the present results, ayanin did not affect xylazine/ketamine-induced anesthesia, suggesting that ayanin has few or no adverse effects, such as nausea, vomiting, and gastric hypersecretion." | 7.76 | Ayanin, a non-selective phosphodiesterase 1-4 inhibitor, effectively suppresses ovalbumin-induced airway hyperresponsiveness without affecting xylazine/ketamine-induced anesthesia. ( Chen, CM; Ko, WC; Lee, FP; Shen, HY; Shih, CM, 2010) |
| " We aimed to investigate the role of oxidative stress, renal inflammation, and apoptosis in the injury of the kidney tissue after ischemic reperfusion, and the protective effect of dose-dependent boric acid administration." | 3.96 | The Role of Oxidative Stress, Renal Inflammation, and Apoptosis in Post Ischemic Reperfusion Injury of Kidney Tissue: the Protective Effect of Dose-Dependent Boric Acid Administration. ( Donmez, DB; Hacioglu, C; Kanbak, G; Kar, F; Senturk, H, 2020) |
| " In contrast to ketamine/xylazine, this represents a more physiological, translatable strategy for suppression of cardiomyocyte (18)F-FDG uptake when targeting myocardial inflammation." | 3.81 | Clinically relevant strategies for lowering cardiomyocyte glucose uptake for 18F-FDG imaging of myocardial inflammation in mice. ( Bankstahl, JP; Bengel, FM; Thackeray, JT; Wang, Y; Wollert, KC, 2015) |
| " We hypothesized that the volatile anesthetic sevoflurane (SEVO) attenuates lung inflammation through activation of lung epithelial GABA(A) receptors." | 3.78 | Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury. ( Fortis, S; Haitsma, JJ; Lu, WY; Mazer, CD; Parotto, M; Slutsky, AS; Spieth, PM; Zhang, H; Zhong, N, 2012) |
| " In the present results, ayanin did not affect xylazine/ketamine-induced anesthesia, suggesting that ayanin has few or no adverse effects, such as nausea, vomiting, and gastric hypersecretion." | 3.76 | Ayanin, a non-selective phosphodiesterase 1-4 inhibitor, effectively suppresses ovalbumin-induced airway hyperresponsiveness without affecting xylazine/ketamine-induced anesthesia. ( Chen, CM; Ko, WC; Lee, FP; Shen, HY; Shih, CM, 2010) |
| " Isoflurane (ISO), ketamine-xylazine (KX), or pentobarbital (PEN) with or without buprenorphine were administered before scald-burn in 72 rats that were euthanized without anesthesia by decapitation after 24 h and compared with unburned shams." | 3.76 | Impact of anesthesia, analgesia, and euthanasia technique on the inflammatory cytokine profile in a rodent model of severe burn injury. ( Al-Mousawi, AM; Branski, LK; Herndon, DN; Jeschke, MG; Kraft, R; Kulp, GA; Mecott, GA; Williams, FN, 2010) |
| "treatment with xylazine or UK14304, two α2-adrenergic agonists, reduced neutrophil migration by 60%." | 1.40 | Prevention of neutrophil extravasation by α2-adrenoceptor-mediated endothelial stabilization. ( Álvarez de La Rosa, D; Arce-Franco, M; Armas-González, E; Barreiro, O; Díaz-González, F; Domínguez-Luis, MJ; Feria, M; Herrera-García, AM; Machado, JD; Pec, MK; Sánchez-Madrid, F, 2014) |
| "The pentobarbital effect was significant within 3 days of surgery and persisted through the remainder of the testing period." | 1.37 | Deleterious impact of a γ-aminobutyric acid type A receptor preferring general anesthetic when used in the presence of persistent inflammation. ( Boegel, K; Gold, MS; Gyulai, FE; Moore, KK, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (80.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Kar, F | 1 |
| Hacioglu, C | 1 |
| Senturk, H | 1 |
| Donmez, DB | 1 |
| Kanbak, G | 1 |
| Herrera-García, AM | 1 |
| Domínguez-Luis, MJ | 1 |
| Arce-Franco, M | 1 |
| Armas-González, E | 1 |
| Álvarez de La Rosa, D | 1 |
| Machado, JD | 1 |
| Pec, MK | 1 |
| Feria, M | 1 |
| Barreiro, O | 1 |
| Sánchez-Madrid, F | 1 |
| Díaz-González, F | 1 |
| Thackeray, JT | 1 |
| Bankstahl, JP | 1 |
| Wang, Y | 1 |
| Wollert, KC | 1 |
| Bengel, FM | 1 |
| Lee, FP | 1 |
| Shih, CM | 1 |
| Shen, HY | 1 |
| Chen, CM | 2 |
| Ko, WC | 1 |
| Whitaker, AM | 1 |
| Sulzer, J | 1 |
| Walker, E | 1 |
| Mathis, K | 1 |
| Molina, PE | 1 |
| Al-Mousawi, AM | 1 |
| Kulp, GA | 1 |
| Branski, LK | 1 |
| Kraft, R | 1 |
| Mecott, GA | 1 |
| Williams, FN | 1 |
| Herndon, DN | 1 |
| Jeschke, MG | 1 |
| Boegel, K | 1 |
| Gyulai, FE | 1 |
| Moore, KK | 1 |
| Gold, MS | 1 |
| Fortis, S | 1 |
| Spieth, PM | 1 |
| Lu, WY | 1 |
| Parotto, M | 1 |
| Haitsma, JJ | 1 |
| Slutsky, AS | 1 |
| Zhong, N | 1 |
| Mazer, CD | 1 |
| Zhang, H | 1 |
| Moore, TC | 1 |
10 other studies available for xylazine and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
The Role of Oxidative Stress, Renal Inflammation, and Apoptosis in Post Ischemic Reperfusion Injury of Kidney Tissue: the Protective Effect of Dose-Dependent Boric Acid Administration.
Topics: Animals; Apoptosis; Boric Acids; Dose-Response Relationship, Drug; Female; Inflammation; Injections, | 2020 |
Prevention of neutrophil extravasation by α2-adrenoceptor-mediated endothelial stabilization.
Topics: Adherens Junctions; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Ant | 2014 |
Clinically relevant strategies for lowering cardiomyocyte glucose uptake for 18F-FDG imaging of myocardial inflammation in mice.
Topics: Anesthetics, General; Animals; Anticoagulants; Fasting; Fluorodeoxyglucose F18; Glucose; Heparin; In | 2015 |
Ayanin, a non-selective phosphodiesterase 1-4 inhibitor, effectively suppresses ovalbumin-induced airway hyperresponsiveness without affecting xylazine/ketamine-induced anesthesia.
Topics: Anesthesia; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Female; Flavonoids; Hypersensi | 2010 |
Sympathetic modulation of the host defense response to infectious challenge during recovery from hemorrhage.
Topics: Animals; Disease Models, Animal; Hemorrhage; Immune Tolerance; Immunity, Innate; Inflammation; Ketam | 2010 |
Impact of anesthesia, analgesia, and euthanasia technique on the inflammatory cytokine profile in a rodent model of severe burn injury.
Topics: Acute-Phase Reaction; Analgesia; Analgesics; Anesthesia, General; Anesthetics; Animals; Buprenorphin | 2010 |
Deleterious impact of a γ-aminobutyric acid type A receptor preferring general anesthetic when used in the presence of persistent inflammation.
Topics: Adrenergic alpha-Agonists; Anesthesia, General; Anesthetics, General; Animals; Behavior, Animal; Exc | 2011 |
Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury.
Topics: Acute Lung Injury; Analysis of Variance; Anesthesia; Anesthetics, Dissociative; Anesthetics, General | 2012 |
Anesthesia-associated depression in lymphocyte traffic and its modulation.
Topics: Anesthesia, General; Animals; Barbiturates; Bradykinin; Cyclic GMP; Depression, Chemical; Drainage; | 1984 |