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xylazine and Heart Failure

xylazine has been researched along with Heart Failure in 4 studies

Xylazine: An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
xylazine : A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"This model can recapitulate stress cardiomyopathy and thereby deepen our understanding of regional cardiac hypo-contractility and prosurvival mechanisms."1.42Immobilization Stress With α2-Adrenergic Stimulation Induces Regional and Transient Reduction of Cardiac Contraction Through Gi Coupling in Rats. ( Kuroda, R; Shintani-Ishida, K; Unuma, K; Yoshida, K, 2015)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Cuijpers, I1
Carai, P1
Mendes-Ferreira, P1
Simmonds, SJ1
Mulder, P1
Miranda-Silva, D1
De Giorgio, D1
Pokreisz, P1
Heymans, S1
Jones, EAV1
Kuroda, R1
Shintani-Ishida, K1
Unuma, K1
Yoshida, K1
Lefkov, SH1
Müssig, D1
Jenkins, WL1
Clark, DR1

Reviews

1 review available for xylazine and Heart Failure

ArticleYear
A review of drugs affecting the heart.
    Journal of the American Veterinary Medical Association, 1977, Jul-01, Volume: 171, Issue:1

    Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Calcium; Catecholamines; Cats; Digitalis Glycosides; Diu

1977

Other Studies

3 other studies available for xylazine and Heart Failure

ArticleYear
The effect of different anaesthetics on echocardiographic evaluation of diastolic dysfunction in a heart failure with preserved ejection fraction model.
    Scientific reports, 2020, 09-24, Volume: 10, Issue:1

    Topics: Anesthetics; Animals; Diastole; Echocardiography; Heart Failure; Heart Rate; Isoflurane; Ketamine; M

2020
Immobilization Stress With α2-Adrenergic Stimulation Induces Regional and Transient Reduction of Cardiac Contraction Through Gi Coupling in Rats.
    International heart journal, 2015, Volume: 56, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; C

2015
Tiletamine-zolazepam and xylazine is a potent cardiodepressive combination: a case report.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2007, Volume: 46, Issue:6

    Topics: Animals; Animals, Laboratory; Anti-Arrhythmia Agents; Body Temperature; Disease Models, Animal; Drug

2007