xylazine has been researched along with Equine Diseases in 50 studies
Xylazine: An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
xylazine : A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 4 mares suffering from dystocia, general anesthesia was induced with xylazine (1." | 7.69 | A case report on the use of guaifenesin-ketamine-xylazine anesthesia for equine dystocia. ( Harrison, IW; Lin, HC; Robbins, RL; Thurmon, JC; Wallace, SS, 1994) |
| "In principal ponies with airway obstruction, xylazine administration significantly (P < 0." | 6.67 | Effects of xylazine on airway function in ponies with recurrent airway obstruction. ( Broadstone, RV; Derksen, FJ; Gray, PR; Robinson, NE, 1992) |
| " The greatest urine volume, similar to changes in peak glucose concentration, always occurred during the first hour after dosing with xylazine and averaged 1." | 5.27 | Xylazine causes transient dose-related hyperglycemia and increased urine volumes in mares. ( Howland, D; Steffey, EP; Thurmon, JC; Woliner, M; Zinkl, JG, 1984) |
| "Treatment with yohimbine prevented xylazine-induced hypoinsulinemia and hyperglycemia." | 5.27 | Effect of yohimbine on xylazine-induced hypoinsulinemia and hyperglycemia in mares. ( Benson, GJ; Greene, SA; Thurmon, JC; Tranquilli, WJ, 1987) |
| " The lower cell counts of caspase- and calprotectin-positive cells in group X may indicate a beneficial effect of xylazine on ischaemia/reperfusion injury." | 4.02 | Preconditioning with lidocaine and xylazine in experimental equine jejunal ischaemia. ( Kästner, S; König, K; Neudeck, S; Pfarrer, C; Rohn, K; Twele, L; Verhaar, N, 2021) |
| "In 4 mares suffering from dystocia, general anesthesia was induced with xylazine (1." | 3.69 | A case report on the use of guaifenesin-ketamine-xylazine anesthesia for equine dystocia. ( Harrison, IW; Lin, HC; Robbins, RL; Thurmon, JC; Wallace, SS, 1994) |
| "of xylazine was injected IA, and blood samples were taken to assess drug systemic absorption." | 2.79 | A pharmacokinetic/clinical approach to postulate a local action of intra-articular xylazine administration in the horse: a preliminary study. ( Bazzica, C; Cagnardi, P; Della Rocca, G; Di Salvo, A; Giontella, A; Nannarone, S, 2014) |
| "In principal ponies with airway obstruction, xylazine administration significantly (P < 0." | 2.67 | Effects of xylazine on airway function in ponies with recurrent airway obstruction. ( Broadstone, RV; Derksen, FJ; Gray, PR; Robinson, NE, 1992) |
| "Mannitol flux was greater in ischemic tissues than in reperfused tissues." | 1.37 | In vitro and in vivo responses of mucosa from the large colon of horses to ischemia and reperfusion. ( Freeman, DE; Graham, AS; Grosche, A; Morton, AJ; Polyak, MM, 2011) |
| "Xylazine sedation was not associated with changes in pulmonary function but did result in markedly decreased REE in controls." | 1.32 | Energetic cost of breathing, body composition, and pulmonary function in horses with recurrent airway obstruction. ( Bedenice, D; Deveney, EF; DeWitt, S; Hoffman, A; Mazan, MR, 2004) |
| " Although it was possible that the clinical findings in these horses may have resulted from use of an inadequate dosage of carfentanil or xylazine, or both, analysis of the results more likely indicated that domestic and exotic horses may respond differently to carfentanil, and domestic horses may not be a good model for use in studies of carfentanil." | 1.29 | Complications with the use of carfentanil citrate and xylazine hydrochloride to immobilize domestic horses. ( Carpenter, JW; Leith, DE; Shaw, ML, 1995) |
| "Hypertension was recorded in 11." | 1.28 | A retrospective survey of anaesthesia in horses with colic. ( Adams, JG; Cowgill, LM; Trim, CM; Ward, SL, 1989) |
| "Changes in respiratory airflow, upper airway obstruction and respiratory noise were noted in the initial 20 mins of sedation, after which respiratory rate fell, tidal volume increased, and minute volume decreased gradually." | 1.28 | Cardiopulmonary effects of xylazine sedation in the foal. ( Carter, SW; Jourdenais, DA; Robertson, SA; Steel, CJ, 1990) |
| "Xylazine was administered into the epidural space of nine horses to facilitate various perineal manipulations (ie rectovaginal laceration repair, replacement of prolapsed rectum and urethral extension)." | 1.28 | Clinical use of epidural xylazine in the horse. ( Caron, JP; LeBlanc, PH, 1990) |
| "Although Horner's syndrome has been reported after perivascular jugular injections these cases illustrate that the syndrome may develop following routine intravenous injections." | 1.27 | Transient Horner's syndrome following routine intravenous injections in two horses. ( Sweeney, CR; Sweeney, RW, 1984) |
| "A xylazine and butorphanol drug combination produced minimal and transient hemodynamic effects and no significant respiratory depression when administered to 6 healthy horses." | 1.27 | A new analgesic drug combination in the horse. ( Muir, WW; Robertson, JT, 1983) |
| " The greatest urine volume, similar to changes in peak glucose concentration, always occurred during the first hour after dosing with xylazine and averaged 1." | 1.27 | Xylazine causes transient dose-related hyperglycemia and increased urine volumes in mares. ( Howland, D; Steffey, EP; Thurmon, JC; Woliner, M; Zinkl, JG, 1984) |
| "Treatment with yohimbine prevented xylazine-induced hypoinsulinemia and hyperglycemia." | 1.27 | Effect of yohimbine on xylazine-induced hypoinsulinemia and hyperglycemia in mares. ( Benson, GJ; Greene, SA; Thurmon, JC; Tranquilli, WJ, 1987) |
| "Unexpected cardiac arrest occurred in two horses during routine surgical anaesthesia." | 1.27 | Cardiac arrest during anaesthesia in two horses. ( Kellagher, RE; Watney, GC, 1986) |
| "Colic was produced by inflating a balloon in the horses' cecum." | 1.27 | Visceral analgesia: effects of xylazine, butorphanol, meperidine, and pentazocine in horses. ( Muir, WW; Robertson, JT, 1985) |
| "Episodes of colic characterized by pawing, anxiety, anorexia, and attempts to lie down during impaction correlated with longer, louder sounds on auscultation and multiple contraction (closely grouped series lasting 3-5 minutes) of greater than 40 mm Hg as interpreted from simultaneous intraluminal pressure recordings." | 1.26 | Equine pelvic flexure impaction. A model used to evaluate motor events and compare drug response. ( Brondum, J; Lowe, JE; Sellers, AF, 1980) |
| "Xylazine was significantly more effective in obtunding deep pain (P less than 0." | 1.26 | Objective tests of analgesic drugs in ponies. ( Lumb, WV; Pippi, NL, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (40.00) | 18.7374 |
| 1990's | 14 (28.00) | 18.2507 |
| 2000's | 8 (16.00) | 29.6817 |
| 2010's | 6 (12.00) | 24.3611 |
| 2020's | 2 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Verhaar, N | 1 |
| Pfarrer, C | 1 |
| Neudeck, S | 1 |
| König, K | 1 |
| Rohn, K | 2 |
| Twele, L | 1 |
| Kästner, S | 1 |
| Joyner, RL | 1 |
| Liu, CC | 1 |
| Cremer, J | 1 |
| Carter, RT | 1 |
| Lewin, AC | 1 |
| Aarnes, TK | 1 |
| Lerche, P | 2 |
| Bednarski, RM | 1 |
| Hubbell, JAE | 1 |
| Di Salvo, A | 1 |
| Della Rocca, G | 1 |
| Bazzica, C | 1 |
| Giontella, A | 1 |
| Cagnardi, P | 1 |
| Nannarone, S | 1 |
| Rettig, MJ | 1 |
| Leelamankong, P | 1 |
| Rungsri, P | 1 |
| Lischer, CJ | 1 |
| Hopster, K | 1 |
| Jacobson, B | 1 |
| Hopster-Iversen, C | 1 |
| Kästner, SBR | 1 |
| Graham, AS | 1 |
| Grosche, A | 2 |
| Morton, AJ | 2 |
| Polyak, MM | 1 |
| Freeman, DE | 1 |
| Varney, CR | 1 |
| Ekiri, AB | 1 |
| Duggan, VE | 1 |
| MacAllister, CG | 1 |
| Davis, MS | 1 |
| Mazan, MR | 2 |
| Hoffman, AM | 1 |
| Kuehn, H | 1 |
| Deveney, EF | 2 |
| Wilson, DV | 1 |
| Rondenay, Y | 1 |
| Shance, PU | 1 |
| DeWitt, S | 1 |
| Bedenice, D | 1 |
| Hoffman, A | 1 |
| Brashier, M | 1 |
| Plummer, AE | 1 |
| Rakestraw, PC | 1 |
| Hardy, J | 1 |
| Lee, RM | 1 |
| Tranquilli, WJ | 3 |
| Thurmon, JC | 5 |
| Neff-Davis, CA | 1 |
| Davis, LE | 2 |
| Benson, GJ | 3 |
| Hoffman, W | 1 |
| Lock, TF | 1 |
| Sweeney, RW | 1 |
| Sweeney, CR | 1 |
| Robertson, JT | 3 |
| Muir, WW | 4 |
| Steffey, EP | 1 |
| Zinkl, JG | 1 |
| Woliner, M | 1 |
| Howland, D | 1 |
| Lowe, JE | 3 |
| Sellers, AF | 1 |
| Brondum, J | 1 |
| Shaw, ML | 1 |
| Carpenter, JW | 1 |
| Leith, DE | 1 |
| Matthews, NS | 1 |
| Light, GS | 1 |
| Sanders, EA | 1 |
| Hartsfield, SM | 1 |
| Hustead, DR | 1 |
| Lin, HC | 1 |
| Wallace, SS | 1 |
| Robbins, RL | 1 |
| Harrison, IW | 1 |
| Chopin, JB | 1 |
| Wright, JD | 1 |
| Raidal, SR | 1 |
| Raidal, SL | 1 |
| Richards, RB | 1 |
| Cosgriff, AV | 1 |
| Rose, KJ | 1 |
| Jochle, W | 1 |
| Moore, JN | 1 |
| Brown, J | 1 |
| Baker, GJ | 1 |
| Fubini, S | 1 |
| Reeves, MJ | 1 |
| Watkins, JP | 1 |
| White, NA | 1 |
| Trim, CM | 1 |
| Adams, JG | 1 |
| Cowgill, LM | 1 |
| Ward, SL | 1 |
| Herholz, C | 1 |
| Tschudi, P | 1 |
| Gerber, H | 1 |
| Moens, Y | 1 |
| Straub, R | 1 |
| Grubb, TL | 1 |
| Constable, PD | 1 |
| Foreman, JH | 1 |
| Olson, WO | 1 |
| Branson, KR | 1 |
| Kramer, J | 1 |
| Hubbell, JA | 1 |
| Beard, W | 1 |
| Miller, T | 1 |
| Badgley, B | 1 |
| Bothwell, V | 1 |
| Kohn, CW | 1 |
| Pippi, NL | 1 |
| Lumb, WV | 1 |
| Fuentes, VO | 1 |
| Skarda, RT | 1 |
| Milne, DW | 1 |
| Yoxall, AT | 1 |
| Donawick, WJ | 1 |
| Hall, LW | 2 |
| Nigam, JM | 1 |
| McCashin, FB | 1 |
| Gabel, AA | 1 |
| England, GC | 2 |
| Clarke, KW | 2 |
| Goossens, L | 1 |
| Broadstone, RV | 1 |
| Gray, PR | 1 |
| Robinson, NE | 1 |
| Derksen, FJ | 1 |
| Curtis, MB | 1 |
| Eicker, SW | 1 |
| Archer, RM | 1 |
| Lindsay, WA | 1 |
| Bryant, CE | 1 |
| Willoughby, RA | 1 |
| Ecker, GL | 1 |
| McKee, SL | 1 |
| Riddolls, LJ | 1 |
| Carter, SW | 1 |
| Robertson, SA | 1 |
| Steel, CJ | 1 |
| Jourdenais, DA | 1 |
| LeBlanc, PH | 1 |
| Caron, JP | 1 |
| Groenendyk, J | 1 |
| Greene, SA | 1 |
| Hilfiger, J | 1 |
| Kellagher, RE | 1 |
| Watney, GC | 1 |
2 reviews available for xylazine and Equine Diseases
| Article | Year |
|---|---|
Preparative management of the equine patient with an abdominal crisis.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; | 1979 |
Metabolic management of the horse with an acute abdominal crisis.
Topics: Animals; Anti-Bacterial Agents; Bicarbonates; Carbon Dioxide; Colic; Horse Diseases; Horses; Hypopro | 1975 |
6 trials available for xylazine and Equine Diseases
| Article | Year |
|---|---|
A pharmacokinetic/clinical approach to postulate a local action of intra-articular xylazine administration in the horse: a preliminary study.
Topics: Analgesics; Animals; Arthroscopy; Horse Diseases; Horses; Injections, Intra-Articular; Joint Disease | 2014 |
Cardiovascular effects of N-butylscopolammonium bromide and xylazine in horses.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Butylscopolammonium Bromide; Cross-Over Studies; Fema | 2011 |
Effect of aerosolized albuterol sulfate on resting energy expenditure determined by use of open-flow indirect calorimetry in horses with recurrent airway obstruction.
Topics: Aerosols; Albuterol; Animals; Basal Metabolism; Calorimetry, Indirect; Horse Diseases; Horses; Hypno | 2003 |
Comparison of detomidine, butorphanol, flunixin meglumine and xylazine in clinical cases of equine colic.
Topics: Adrenergic alpha-Agonists; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-St | 1989 |
Comparison of four drug combinations for total intravenous anesthesia of horses undergoing surgical removal of an abdominal testis.
Topics: Adrenergic alpha-Agonists; Analgesia; Analgesics; Anesthesia, Intravenous; Anesthetics, Combined; An | 2000 |
Effects of xylazine on airway function in ponies with recurrent airway obstruction.
Topics: Airway Obstruction; Airway Resistance; Animals; Carbon Dioxide; Horse Diseases; Horses; Lung Complia | 1992 |
42 other studies available for xylazine and Equine Diseases
| Article | Year |
|---|---|
Preconditioning with lidocaine and xylazine in experimental equine jejunal ischaemia.
Topics: Animals; Horse Diseases; Horses; Ischemia; Lidocaine; Reperfusion Injury; Xylazine | 2021 |
Intraocular pressure following four different intravenous sedation protocols in normal horses.
Topics: Animals; Butorphanol; Eye Diseases; Horse Diseases; Horses; Intraocular Pressure; Tonometry, Ocular; | 2021 |
Total intravenous anesthesia using a midazolam-ketamine-xylazine infusion in horses: 46 cases (2011-2014).
Topics: Anesthesia, Intravenous; Anesthetics, Dissociative; Animals; Drug Therapy, Combination; Horse Diseas | 2018 |
Effect of sedation on fore- and hindlimb lameness evaluation using body-mounted inertial sensors.
Topics: Accelerometry; Animals; Conscious Sedation; Female; Horse Diseases; Horses; Hypnotics and Sedatives; | 2016 |
Histopathological changes and mRNA expression in lungs of horses after inhalation anaesthesia with different ventilation strategies.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Gene Expression Regulation; Horse Diseases | 2016 |
In vitro and in vivo responses of mucosa from the large colon of horses to ischemia and reperfusion.
Topics: Analysis of Variance; Anesthetics, Intravenous; Animals; Colon; Diazepam; Electric Impedance; Horse | 2011 |
Xylazine-induced attenuation of dorsal displacement of the soft palate associated with epiglottic dysfunction in a horse.
Topics: Adrenergic alpha-Agonists; Animals; Epiglottis; Female; Horse Diseases; Horses; Palate, Soft; Physic | 2002 |
The cardiopulmonary effects of severe blood loss in anesthetized horses.
Topics: Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Inhalation; Animals; Blood Gas Analysis | 2003 |
Energetic cost of breathing, body composition, and pulmonary function in horses with recurrent airway obstruction.
Topics: Adrenergic alpha-Agonists; Aerosols; Airway Obstruction; Animals; Body Composition; Bronchodilator A | 2004 |
Fluphenazine-induced extrapyramidal side effects in a horse.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Diphenhydramine; Extrapyramidal Tracts; Fluph | 2006 |
Outcome of medical and surgical treatment of cecal impaction in horses: 114 cases (1994-2004).
Topics: Animals; Cecum; Clonixin; Fecal Impaction; Female; Follow-Up Studies; Horse Diseases; Horses; Isoton | 2007 |
Hyperglycemia and hypoinsulinemia during xylazine-ketamine anesthesia in Thoroughbred horses.
Topics: Anesthesia; Animals; Blood Glucose; Catecholamines; Female; Horse Diseases; Horses; Hyperglycemia; I | 1984 |
Transient Horner's syndrome following routine intravenous injections in two horses.
Topics: Adrenergic Fibers; Animals; Horner Syndrome; Horse Diseases; Horses; Injections, Intravenous; Jugula | 1984 |
A new analgesic drug combination in the horse.
Topics: Analgesia; Animals; Butorphanol; Cardiac Output; Drug Combinations; Heart Rate; Horse Diseases; Hors | 1983 |
Xylazine causes transient dose-related hyperglycemia and increased urine volumes in mares.
Topics: Analgesia; Animals; Blood Glucose; Cattle; Female; Horse Diseases; Horses; Hyperglycemia; Thiazines; | 1984 |
Equine pelvic flexure impaction. A model used to evaluate motor events and compare drug response.
Topics: Animals; Clonixin; Colic; Colon; Colonic Diseases; Horse Diseases; Horses; Intestinal Obstruction; R | 1980 |
Complications with the use of carfentanil citrate and xylazine hydrochloride to immobilize domestic horses.
Topics: Analgesics, Opioid; Animals; Animals, Domestic; Fentanyl; Horse Diseases; Horses; Hypertension; Immo | 1995 |
Urticarial response during anesthesia in a horse.
Topics: Anesthesia; Animals; Guaifenesin; Horse Diseases; Horses; Ketamine; Male; Preanesthetic Medication; | 1993 |
A case report on the use of guaifenesin-ketamine-xylazine anesthesia for equine dystocia.
Topics: Anesthesia, General; Anesthesia, Obstetrical; Animals; Dystocia; Extraction, Obstetrical; Female; Gu | 1994 |
Complication after the use of a combination of lignocaine and xylazine for epidural anaesthesia in a mare.
Topics: Anesthesia, Epidural; Anesthetics; Animals; Drug Interactions; Female; Horse Diseases; Horses; Lidoc | 1995 |
Acute paraplegia in a thoroughbred racehorse after general anaesthesia.
Topics: Acute Disease; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, General; Animals; Hemorr | 1997 |
A retrospective survey of anaesthesia in horses with colic.
Topics: Administration, Inhalation; Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthet | 1989 |
Ultrasound spirometry in the horse: a preliminary report on the method and the effects of xylazine and lobeline hydrochloride medication.
Topics: Animals; Bronchiolitis; Chronic Disease; Horse Diseases; Horses; Lobeline; Lung; Reference Values; R | 1997 |
Techniques for evaluation of right ventricular relaxation rate in horses and effects of inhalant anesthetics with and without intravenous administration of calcium gluconate.
Topics: Anesthetics, Inhalation; Animals; Calcium Gluconate; Female; Halothane; Heart Function Tests; Heart | 1999 |
Anesthesia case of the month. Diaphragmatic hernia making it difficult to ventilate a horse during anesthesia.
Topics: Adrenergic alpha-Agonists; Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; | 2000 |
Objective tests of analgesic drugs in ponies.
Topics: Analgesics; Animals; Disease Models, Animal; Female; Fentanyl; Horse Diseases; Horses; Male; Meperid | 1979 |
Sudden death in a stallion after xylazine medication.
Topics: Animals; Horse Diseases; Horses; Male; Thiazines; Xylazine | 1978 |
Evaluation of xylazine and ketamine hydrochloride for anesthesia in horses.
Topics: Analgesia; Anesthesia, Intravenous; Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Female; | 1977 |
Radiological protection in equine radiography and radiotherapy.
Topics: Anesthesia; Animals; England; Head; Horse Diseases; Horses; Humans; Immobilization; Legislation, Vet | 1977 |
Papers and articles measurement of central venous pressure in horses.
Topics: Acepromazine; Anesthesia; Anesthesia, Inhalation; Animals; Blood Pressure; Catheterization; Central | 1975 |
Evaluation of xylazine as a sedative and preanesthetic agent in horses.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Arginase; Aspartate Aminotransferases; Blo | 1975 |
A comparison of the sedative effects of three alpha 2-adrenoceptor agonists (romifidine, detomidine and xylazine) in the horse.
Topics: Acoustic Stimulation; Adrenergic alpha-Agonists; Animals; Ataxia; Heart Rate; Horse Diseases; Horses | 1992 |
Anesthetic management of an incisional dehiscence in recovery following exploratory laparotomy in a horse.
Topics: Anesthesia, Intravenous; Animals; Blood Gas Analysis; Blood Pressure; Calculi; Carbon Dioxide; Colon | 1992 |
Comparison of the sedative effects of medetomidine and xylazine in horses.
Topics: Animals; Ataxia; Female; Heart Rate; Horse Diseases; Horses; Hypnotics and Sedatives; Imidazoles; Ma | 1991 |
Use of scintigraphy for the determination of mucociliary clearance rates in normal, sedated, diseased and exercised horses.
Topics: Animals; Exercise Test; Horse Diseases; Horses; Hypnotics and Sedatives; Imidazoles; Lung Diseases, | 1991 |
Cardiopulmonary effects of xylazine sedation in the foal.
Topics: Airway Obstruction; Animals; Animals, Newborn; Blood Pressure; Female; Heart Rate; Hemodynamics; Hor | 1990 |
Clinical use of epidural xylazine in the horse.
Topics: Analgesia, Epidural; Animals; Female; Horse Diseases; Horses; Perineum; Rectal Prolapse; Rectum; Thi | 1990 |
Unusual reaction following overdose of xylazine in a mare.
Topics: Animals; Female; Horse Diseases; Horses; Thiazines; Xylazine | 1989 |
Effect of yohimbine on xylazine-induced hypoinsulinemia and hyperglycemia in mares.
Topics: Animals; Blood Glucose; Female; Horse Diseases; Horses; Hyperglycemia; Insulin; Thiazines; Xylazine; | 1987 |
Analgesic and sedative effects of detomidine compared to xylazine in a colic model using i.v. and i.m. routes of administration.
Topics: Analgesics; Animals; Cecal Diseases; Colic; Female; Horse Diseases; Horses; Hypnotics and Sedatives; | 1986 |
Cardiac arrest during anaesthesia in two horses.
Topics: Anesthesia; Animals; Electrocardiography; Heart Arrest; Heart Block; Heart Rate; Horse Diseases; Hor | 1986 |
Visceral analgesia: effects of xylazine, butorphanol, meperidine, and pentazocine in horses.
Topics: Analgesia; Animals; Behavior, Animal; Butorphanol; Colic; Female; Heart; Horse Diseases; Horses; Mal | 1985 |