xylazine has been researched along with Emesis in 21 studies
Xylazine: An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
xylazine : A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The xylazine/ketamine anesthesia test is widely used as a predictor of the emetic potential of pharmacological compounds in rats." | 7.91 | Validation of the xylazine/ketamine anesthesia test as a predictor of the emetic potential of pharmacological compounds in rats. ( Bonassoli, VT; Heckman, PRA; Nelissen, E; Prickaerts, J; Suay, D; van Goethem, NP; van Hagen, BTJ; Wouters, C, 2019) |
| "To determine the effectiveness of xylazine for the induction of emesis in cats that were suspected of ingesting potentially toxic substances or foreign objects." | 7.85 | Retrospective evaluation of the effectiveness of xylazine for inducing emesis in cats: 48 cats (2011-2015). ( Bracker, K; Sinnott, V; Thies, M, 2017) |
| " administration of xylazine hydrochloride and dexmedetomidine hydrochloride for the induction of emesis in cats." | 7.83 | Evaluation and comparison of xylazine hydrochloride and dexmedetomidine hydrochloride for the induction of emesis in cats: 47 cases (2007-2013). ( Clare, MC; Claypool, SP; Julius, TM; Willey, JL, 2016) |
| "To compare the use of dexmedetomidine hydrochloride, xylazine hydrochloride, and hydrogen peroxide for emesis induction in cats." | 7.81 | Assessment of dexmedetomidine and other agents for emesis induction in cats: 43 cases (2009-2014). ( Drobatz, KJ; Thawley, VJ, 2015) |
| "The present study was conducted in order to clarify the anti-emetic effect of oculo-acupuncture (OA) on dogs with xylazine-induced vomiting, and also to compare the anti-emetic effect of OA and body acupuncture (AP)." | 7.74 | Anti-emetic effect of oculo-acupuncture on dogs with xylazine induced vomiting. ( Kim, DH; Lee, JY; Lee, SE; Lee, YT; Liu, J, 2007) |
| " A supplementary experiment revealed that lorazepam suppressed motion sickness at a dose that produced ataxia, but did not suppress xylazine-induced emesis." | 7.67 | 8-OH-DPAT suppresses vomiting in the cat elicited by motion, cisplatin or xylazine. ( Crampton, GH; Lucot, JB, 1989) |
| "The possible role of the alpha-2 adrenoceptors in xylazine-induced vomiting and in motion sickness was investigated." | 7.67 | Xylazine emesis, yohimbine and motion sickness susceptibility in the cat. ( Crampton, GH; Lucot, JB, 1986) |
| "Xylazine is an effective sedative analgesic that induces vomiting in the cat." | 7.66 | Emetic action of xylazine on the chemoreceptor trigger zone for vomiting in cats. ( Borison, HL; Colby, ED; McCarthy, LE, 1981) |
| " Prior treatment with each dosage of metoclopramide significantly reduced the frequency of emetic episodes (P<0." | 5.36 | Effects of metoclopramide on emesis in cats sedated with xylazine hydrochloride. ( Jarolmasjed, S; Kolahian, S, 2010) |
| "Zacopride was also administered before motion testing (0." | 5.28 | Blockade of 5-hydroxytryptamine3 receptors prevents cisplatin-induced but not motion- or xylazine-induced emesis in the cat. ( Lucot, JB, 1989) |
| "Buspirone pretreatment (4." | 5.27 | Buspirone blocks motion sickness and xylazine-induced emesis in the cat. ( Crampton, GH; Lucot, JB, 1987) |
| "The xylazine/ketamine anesthesia test is widely used as a predictor of the emetic potential of pharmacological compounds in rats." | 3.91 | Validation of the xylazine/ketamine anesthesia test as a predictor of the emetic potential of pharmacological compounds in rats. ( Bonassoli, VT; Heckman, PRA; Nelissen, E; Prickaerts, J; Suay, D; van Goethem, NP; van Hagen, BTJ; Wouters, C, 2019) |
| "To determine the effectiveness of xylazine for the induction of emesis in cats that were suspected of ingesting potentially toxic substances or foreign objects." | 3.85 | Retrospective evaluation of the effectiveness of xylazine for inducing emesis in cats: 48 cats (2011-2015). ( Bracker, K; Sinnott, V; Thies, M, 2017) |
| " administration of xylazine hydrochloride and dexmedetomidine hydrochloride for the induction of emesis in cats." | 3.83 | Evaluation and comparison of xylazine hydrochloride and dexmedetomidine hydrochloride for the induction of emesis in cats: 47 cases (2007-2013). ( Clare, MC; Claypool, SP; Julius, TM; Willey, JL, 2016) |
| "To compare the use of dexmedetomidine hydrochloride, xylazine hydrochloride, and hydrogen peroxide for emesis induction in cats." | 3.81 | Assessment of dexmedetomidine and other agents for emesis induction in cats: 43 cases (2009-2014). ( Drobatz, KJ; Thawley, VJ, 2015) |
| "The present study was conducted in order to clarify the anti-emetic effect of oculo-acupuncture (OA) on dogs with xylazine-induced vomiting, and also to compare the anti-emetic effect of OA and body acupuncture (AP)." | 3.74 | Anti-emetic effect of oculo-acupuncture on dogs with xylazine induced vomiting. ( Kim, DH; Lee, JY; Lee, SE; Lee, YT; Liu, J, 2007) |
| " Flesinoxan produced a dose-dependent suppression of motion sickness and also reduced xylazine-induced emesis at higher doses." | 3.69 | Antiemetic effects of flesinoxan in cats: comparisons with 8-hydroxy-2-(di-n-propylamino)tetralin. ( Lucot, JB, 1994) |
| ") injection of clonidine, xylazine, adrenaline and methoxamine elicited dose-dependent vomiting in cats in that order of potency." | 3.68 | Central alpha-adrenoceptor subtypes involved in the emetic pathway in cats. ( Akiba, T; Hikasa, Y; Iino, Y; Matsukura, M; Ogasawara, S; Takase, K, 1992) |
| " A supplementary experiment revealed that lorazepam suppressed motion sickness at a dose that produced ataxia, but did not suppress xylazine-induced emesis." | 3.67 | 8-OH-DPAT suppresses vomiting in the cat elicited by motion, cisplatin or xylazine. ( Crampton, GH; Lucot, JB, 1989) |
| "Intramuscular injection of xylazine induced dose-dependent vomiting in cats (ED50 = 0." | 3.67 | Evidence for the involvement of alpha 2-adrenoceptors in the emetic action of xylazine in cats. ( Hikasa, Y; Ogasawara, S; Takase, K, 1989) |
| "The possible role of the alpha-2 adrenoceptors in xylazine-induced vomiting and in motion sickness was investigated." | 3.67 | Xylazine emesis, yohimbine and motion sickness susceptibility in the cat. ( Crampton, GH; Lucot, JB, 1986) |
| "Xylazine is an effective sedative analgesic that induces vomiting in the cat." | 3.66 | Emetic action of xylazine on the chemoreceptor trigger zone for vomiting in cats. ( Borison, HL; Colby, ED; McCarthy, LE, 1981) |
| " Prior treatment with each dosage of metoclopramide significantly reduced the frequency of emetic episodes (P<0." | 1.36 | Effects of metoclopramide on emesis in cats sedated with xylazine hydrochloride. ( Jarolmasjed, S; Kolahian, S, 2010) |
| "Xylazine and ketamine was administered simultaneously via intratesticularly (IT group), intramuscularly (IM group) or intravenously (IV group) at doses of 2 and 10 mg/kg, respectively." | 1.32 | Effect of intratesticular injection of xylazine/ketamine combination on canine castration. ( Jeong, MB; Jeong, SM; Kim, JK; Lee, ES; Nam, TC; Seo, KM; Yi, NY, 2004) |
| "Emesis was characterized by expulsion of solid or liquid material." | 1.29 | Emesis induced in domestic pigs: a new experimental tool for detection of antiemetic drugs and for evaluation of emetogenic potential of new anticancer agents. ( Göthert, M; Herold, H; Szelenyi, I, 1994) |
| "Zacopride was also administered before motion testing (0." | 1.28 | Blockade of 5-hydroxytryptamine3 receptors prevents cisplatin-induced but not motion- or xylazine-induced emesis in the cat. ( Lucot, JB, 1989) |
| "Buspirone pretreatment (4." | 1.27 | Buspirone blocks motion sickness and xylazine-induced emesis in the cat. ( Crampton, GH; Lucot, JB, 1987) |
| "Vomiting was produced by the xylazine in 36 cats." | 1.26 | Clinical observations on xylazine/ketamine anaesthesia in the cat. ( Cullen, LK; Jones, RS, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (42.86) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thies, M | 1 |
| Bracker, K | 1 |
| Sinnott, V | 1 |
| Nelissen, E | 1 |
| van Goethem, NP | 1 |
| Bonassoli, VT | 1 |
| Heckman, PRA | 1 |
| van Hagen, BTJ | 1 |
| Suay, D | 1 |
| Wouters, C | 1 |
| Prickaerts, J | 1 |
| Thawley, VJ | 1 |
| Drobatz, KJ | 1 |
| Willey, JL | 1 |
| Julius, TM | 1 |
| Claypool, SP | 1 |
| Clare, MC | 1 |
| Kolahian, S | 2 |
| Jarolmasjed, S | 1 |
| Jarolmasjed, SH | 1 |
| Kim, JK | 1 |
| Jeong, SM | 1 |
| Yi, NY | 1 |
| Jeong, MB | 1 |
| Lee, ES | 1 |
| Nam, TC | 1 |
| Seo, KM | 1 |
| Liu, J | 1 |
| Lee, YT | 1 |
| Lee, SE | 1 |
| Lee, JY | 1 |
| Kim, DH | 1 |
| Colby, ED | 1 |
| McCarthy, LE | 1 |
| Borison, HL | 1 |
| Szelenyi, I | 1 |
| Herold, H | 1 |
| Göthert, M | 1 |
| Lucot, JB | 5 |
| Ho, CM | 1 |
| Ho, ST | 1 |
| Wang, JJ | 1 |
| Lee, TY | 1 |
| Chai, CY | 1 |
| Cullen, LK | 1 |
| Jones, RS | 1 |
| Klide, AM | 1 |
| Calderwood, HW | 1 |
| Soma, LR | 1 |
| Hikasa, Y | 3 |
| Akiba, T | 1 |
| Iino, Y | 1 |
| Matsukura, M | 1 |
| Takase, K | 3 |
| Ogasawara, S | 3 |
| Crampton, GH | 3 |
| Osada, T | 1 |
| Takamatsu, H | 1 |
21 other studies available for xylazine and Emesis
| Article | Year |
|---|---|
Retrospective evaluation of the effectiveness of xylazine for inducing emesis in cats: 48 cats (2011-2015).
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Cats; Female; Foreign Bodies; Male; Poisoning; Retros | 2017 |
Validation of the xylazine/ketamine anesthesia test as a predictor of the emetic potential of pharmacological compounds in rats.
Topics: Anesthesia; Animals; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; | 2019 |
Assessment of dexmedetomidine and other agents for emesis induction in cats: 43 cases (2009-2014).
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Cat Diseases; Cats; Dexmedetomidine; Emetics; Female; | 2015 |
Evaluation and comparison of xylazine hydrochloride and dexmedetomidine hydrochloride for the induction of emesis in cats: 47 cases (2007-2013).
Topics: Animals; Cat Diseases; Cats; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Injections, | 2016 |
Effects of metoclopramide on emesis in cats sedated with xylazine hydrochloride.
Topics: Animals; Antiemetics; Cat Diseases; Cats; Female; Hypnotics and Sedatives; Male; Metoclopramide; Sod | 2010 |
Antiemetic efficacy of promethazine on xylazine-induced emesis in cats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antiemetics; Cat Diseases; Cats; Dose-Response Relati | 2012 |
Effect of intratesticular injection of xylazine/ketamine combination on canine castration.
Topics: Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Body Temperature | 2004 |
Anti-emetic effect of oculo-acupuncture on dogs with xylazine induced vomiting.
Topics: Acupuncture Points; Acupuncture Therapy; Adrenergic alpha-Agonists; Animals; Dogs; Female; Male; Vom | 2007 |
Emetic action of xylazine on the chemoreceptor trigger zone for vomiting in cats.
Topics: Animals; Cats; Female; Injections, Intramuscular; Male; Medulla Oblongata; Thiazines; Vomiting; Xyla | 1981 |
Emesis induced in domestic pigs: a new experimental tool for detection of antiemetic drugs and for evaluation of emetogenic potential of new anticancer agents.
Topics: Animals; Antiemetics; Antineoplastic Agents; Carboplatin; Cisplatin; Cyclophosphamide; Dactinomycin; | 1994 |
Antiemetic effects of flesinoxan in cats: comparisons with 8-hydroxy-2-(di-n-propylamino)tetralin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antiemetics; Behavior, Animal | 1994 |
Effects of dexamethasone on emesis in cats sedated with xylazine hydrochloride.
Topics: Adrenergic alpha-Agonists; Animals; Cats; Dexamethasone; Female; Glucocorticoids; Male; Vomiting; Xy | 2001 |
Clinical observations on xylazine/ketamine anaesthesia in the cat.
Topics: Anesthesia; Animals; Cat Diseases; Cats; Female; Ketamine; Male; Surgical Procedures, Operative; Thi | 1977 |
Cardiopulmonary effects of xylazine in dogs.
Topics: Animals; Aorta; Arrhythmia, Sinus; Atropine; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Ca | 1975 |
Central alpha-adrenoceptor subtypes involved in the emetic pathway in cats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Dose-Response Rel | 1992 |
8-OH-DPAT suppresses vomiting in the cat elicited by motion, cisplatin or xylazine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Cisplatin; Dose-Response Relationship, Drug; | 1989 |
Evidence for the involvement of alpha 2-adrenoceptors in the emetic action of xylazine in cats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Cat Diseases; Cats; Ch | 1989 |
Blockade of 5-hydroxytryptamine3 receptors prevents cisplatin-induced but not motion- or xylazine-induced emesis in the cat.
Topics: Animals; Antiemetics; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic | 1989 |
Xylazine emesis, yohimbine and motion sickness susceptibility in the cat.
Topics: Animals; Apomorphine; Brain; Cats; Disease Susceptibility; Dose-Response Relationship, Drug; Female; | 1986 |
Xylazine-induced vomiting in dogs: elimination by ablation of the area postrema and blockade by yohimbine.
Topics: Animals; Chemoreceptor Cells; Dog Diseases; Dogs; Female; Male; Medulla Oblongata; Thiazines; Vomiti | 1987 |
Buspirone blocks motion sickness and xylazine-induced emesis in the cat.
Topics: Animals; Buspirone; Cats; Female; Motion Sickness; Vomiting; Xylazine | 1987 |