Page last updated: 2024-11-05

xylazine and Canine Diseases

xylazine has been researched along with Canine Diseases in 20 studies

Xylazine: An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
xylazine : A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.

Research Excerpts

ExcerptRelevanceReference
"Ventricular arryhythmias including ventricular fibrillation were produced with epinephrine in dogs induced to an anesthetic state with thiamylal and maintained with halothane."7.65Effects of xylazine and acetylpromazine upon induced ventricular fibrillation in dogs anesthetized with thiamylal and halothane. ( Hamlin, RL; Muir, WW; Werner, LL, 1975)
"The reproductive and growth hormone status of a group of 12 neutered dogs affected by idiopathic recurrent flank alopecia was investigated at both maximum and minimum photoperiod using the adrenocorticotrophic hormone (ACTH) stimulation test, the xylazine stimulation test and the insulin-like growth factor I (IGF-I) assay."3.69Investigation of the reproductive and growth hormone status of dogs affected by idiopathic recurrent flank alopecia. ( Curtis, CF; Evans, H; Lloyd, DH, 1996)
" Acepromazine, ketamine, xylazine, droperidol-fentamyl, and combinations of these drugs were evaluated for effects on blood pressure, intraocular pressure, and restraint of the dog for 4 minutes of Schiotz tonography of each eye."3.65Tonography in the normal and glaucomatous beagle. ( Gelatt, KN; Gum, GG; Gwin, RM; Peiffer, RL, 1977)
"Ventricular arryhythmias including ventricular fibrillation were produced with epinephrine in dogs induced to an anesthetic state with thiamylal and maintained with halothane."3.65Effects of xylazine and acetylpromazine upon induced ventricular fibrillation in dogs anesthetized with thiamylal and halothane. ( Hamlin, RL; Muir, WW; Werner, LL, 1975)
"Clinical signs, typical of ehrlichiosis, included mucopurulent ocular discharge, lymphadenopathy and malaise with accompanying pyrexia, leukopenia and thrombocytopenia."1.30Experimental transmission of Ehrlichia canis (Rickettsiales: Ehrlichieae) by Dermacentor variabilis (Acari: Ixodidae). ( Barker, RW; Crow, DW; Ewing, SA; Fox, JC; Johnson, EM; Kocan, KM, 1998)
"Before treatment of the hyperadrenocorticism, no significant increase in growth hormone concentration occurred in any of the dogs following the administration of xylazine."1.26Suppression of growth hormone secretion in spontaneous canine hyperadrenocorticism and its reversal after treatment. ( Altszuler, N; Peterson, ME, 1981)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199012 (60.00)18.7374
1990's7 (35.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Herrera Becerra, JR1
Monteiro, ER1
Martins, LG1
Baier, ME1
Santos, EA1
Bianchi, SP1
Berry, AP1
Arbuckle, JB1
Nicol, J1
Short, CE1
Folkers, ER1
Peterson, ME1
Altszuler, N1
Day, TK1
Muir, WW2
Curtis, CF1
Evans, H1
Lloyd, DH1
Johnson, EM1
Ewing, SA1
Barker, RW1
Fox, JC1
Crow, DW1
Kocan, KM1
Redondo, JI1
Gómez-Villamandos, RJ1
Santisteban, JM1
Domínguez, JM1
Ruiz, I1
Avila, I1
Jenkins, WL1
Clark, DR1
Gelatt, KN1
Gwin, RM1
Peiffer, RL1
Gum, GG1
Klide, AM1
Calderwood, HW1
Soma, LR1
Werner, LL1
Hamlin, RL1
Mansell, PD1
Parry, BW1
Frank, LA1
Kunkle, GA2
Beale, KM2
Chalker, L1
Cannon, R1
Hikasa, Y1
Takase, K1
Osada, T1
Takamatsu, H1
Ogasawara, S1
Tranquilli, WJ2
Thurmon, JC2
Benson, GJ2
Kommonen, B1
Raitta, C1
Davis, LE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Dexamedetomidine for Interscalene Brachial Plexus Block on Plasma Cortisol and IL-6 After Rotator Cuff Repair: a Prospective Randomized Study[NCT02766556]50 participants (Actual)Interventional2014-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for xylazine and Canine Diseases

ArticleYear
A review of drugs affecting the heart.
    Journal of the American Veterinary Medical Association, 1977, Jul-01, Volume: 171, Issue:1

    Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Calcium; Catecholamines; Cats; Digitalis Glycosides; Diu

1977

Trials

1 trial available for xylazine and Canine Diseases

ArticleYear
Epidural administration of combinations of ropivacaine, morphine and xylazine in bitches undergoing total unilateral mastectomy: a randomized clinical trial.
    Veterinary anaesthesia and analgesia, 2022, Volume: 49, Issue:1

    Topics: Analgesics, Opioid; Animals; Dog Diseases; Dogs; Mastectomy; Morphine; Pain, Postoperative; Prospect

2022

Other Studies

18 other studies available for xylazine and Canine Diseases

ArticleYear
Cyclonite poisoning in a dog.
    The Veterinary record, 1983, Nov-05, Volume: 113, Issue:19

    Topics: Acepromazine; Animals; Dog Diseases; Dogs; Drug Therapy, Combination; Ketamine; Male; Pentobarbital;

1983
Doxapram for reversing xylazine sedation.
    Journal of the American Veterinary Medical Association, 1984, Feb-01, Volume: 184, Issue:3

    Topics: Anesthesia; Animals; Dog Diseases; Dogs; Doxapram; Thiazines; Xylazine

1984
Xylazine precaution.
    Journal of the American Veterinary Medical Association, 1980, May-15, Volume: 176, Issue:10 Pt 1

    Topics: Aerophagy; Animals; Dog Diseases; Dogs; Humans; Thiazines; Xylazine

1980
Suppression of growth hormone secretion in spontaneous canine hyperadrenocorticism and its reversal after treatment.
    American journal of veterinary research, 1981, Volume: 42, Issue:11

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Animals; Cushing Syndrome; Dog Disea

1981
Alpha 2-adrenergic receptor agonist effects on supraventricular and ventricular automaticity in dogs with complete atrioventricular block.
    American journal of veterinary research, 1993, Volume: 54, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dog Diseases; Dogs; Formaldehyde;

1993
Investigation of the reproductive and growth hormone status of dogs affected by idiopathic recurrent flank alopecia.
    The Journal of small animal practice, 1996, Volume: 37, Issue:9

    Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Alopecia; Androstenedione; Animals; Dog D

1996
Experimental transmission of Ehrlichia canis (Rickettsiales: Ehrlichieae) by Dermacentor variabilis (Acari: Ixodidae).
    Veterinary parasitology, 1998, Jan-31, Volume: 74, Issue:2-4

    Topics: Anesthetics, Dissociative; Animals; Arachnid Vectors; Dermacentor; Dog Diseases; Dogs; Ehrlichia; Eh

1998
Romifidine, medetomidine or xylazine before propofol-halothane-N2O anesthesia in dogs.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1999, Volume: 63, Issue:1

    Topics: Adrenergic alpha-Agonists; Anesthetics; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals;

1999
Tonography in the normal and glaucomatous beagle.
    American journal of veterinary research, 1977, Volume: 38, Issue:4

    Topics: Acepromazine; Animals; Aqueous Humor; Atropine; Blood Pressure; Dog Diseases; Dogs; Droperidol; Drug

1977
Cardiopulmonary effects of xylazine in dogs.
    American journal of veterinary research, 1975, Volume: 36, Issue:7

    Topics: Animals; Aorta; Arrhythmia, Sinus; Atropine; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Ca

1975
Effects of xylazine and acetylpromazine upon induced ventricular fibrillation in dogs anesthetized with thiamylal and halothane.
    American journal of veterinary research, 1975, Volume: 36, Issue:9

    Topics: Anesthesia; Anesthesia, Inhalation; Animals; Blood Pressure; Dog Diseases; Dogs; Epinephrine; Female

1975
Effect of acepromazine, xylazine and thiopentone on factor VIII activity and von Willebrand factor antigen concentration in dogs.
    Australian veterinary journal, 1992, Volume: 69, Issue:8

    Topics: Acepromazine; Animals; Blood Coagulation Factors; Blood Proteins; Dog Diseases; Dogs; Factor VIII; F

1992
Comparison of serum cortisol concentration before and after intradermal testing in sedated and nonsedated dogs.
    Journal of the American Veterinary Medical Association, 1992, Feb-15, Volume: 200, Issue:4

    Topics: Animals; Dog Diseases; Dogs; False Negative Reactions; Female; Hydrocortisone; Intradermal Tests; Ma

1992
Effects of sedation on intradermal skin testing in flea-allergic dogs.
    Journal of the American Veterinary Medical Association, 1990, Oct-01, Volume: 197, Issue:7

    Topics: Acepromazine; Animals; Diazepam; Dog Diseases; Dogs; Drug Combinations; Histamine; Hypersensitivity;

1990
Xylazine-induced vomiting in dogs: elimination by ablation of the area postrema and blockade by yohimbine.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1987, Volume: 34, Issue:2

    Topics: Animals; Chemoreceptor Cells; Dog Diseases; Dogs; Female; Male; Medulla Oblongata; Thiazines; Vomiti

1987
Alterations in epinephrine-induced arrhythmogenesis after xylazine and subsequent yohimbine administration in isoflurane-anesthetized dogs.
    American journal of veterinary research, 1988, Volume: 49, Issue:7

    Topics: Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Blood Pressure; Dog Diseases; Dogs; Epinephri

1988
Electroretinography in Labrador retrievers given ketamine-xylazine anesthesia.
    American journal of veterinary research, 1987, Volume: 48, Issue:9

    Topics: Animals; Dog Diseases; Dogs; Electroretinography; Female; Ketamine; Male; Photic Stimulation; Retina

1987
Alteration in the arrhythmogenic dose of epinephrine (ADE) following xylazine administration to halothane-anesthetized dogs.
    Journal of veterinary pharmacology and therapeutics, 1986, Volume: 9, Issue:2

    Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Blood Pressure; Dog Diseases; Dogs; Dose-Respons

1986